Christopher R. Jacobs

Biomedical Engineering Columbia University, New York, NY 
Biomedical Engineering, Cell Biology, Medicine and Surgery
"Christopher Jacobs"


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Dennis R. Carter grad student 1994 Stanford (Physics Tree)
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Sutton MM, Duffy MP, Verbruggen SW, et al. (2023) Osteoclastogenesis requires primary cilia disassembly and can be inhibited by promoting primary cilia formation pharmacologically. Cells, Tissues, Organs
Spasic M, Duffy MP, Jacobs CR. (2022) Fenoldopam sensitizes primary cilia-mediated mechanosensing to promote osteogenic intercellular signaling and whole bone adaptation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research
Moore ER, Chen JC, Jacobs CR. (2019) Prx1-Expressing Progenitor Primary Cilia Mediate Bone Formation in response to Mechanical Loading in Mice. Stem Cells International. 2019: 3094154
Moore ER, Yang Y, Jacobs CR. (2018) Primary cilia are necessary for Prx1-expressing cells to contribute to postnatal skeletogenesis. Journal of Cell Science
Moore ER, Zhu YX, Ryu HS, et al. (2018) Periosteal progenitors contribute to load-induced bone formation in adult mice and require primary cilia to sense mechanical stimulation. Stem Cell Research & Therapy. 9: 190
Moore ER, Jacobs CR. (2017) The primary cilium as a signaling nexus for growth plate function and subsequent skeletal development. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Spasic M, Jacobs CR. (2017) Primary cilia: Cell and molecular mechanosensors directing whole tissue function. Seminars in Cell & Developmental Biology
Spasic M, Jacobs CR. (2017) Lengthening primary cilia enhances cellular mechanosensitivity. European Cells & Materials. 33: 158-168
Chen JC, Hoey DA, Chua M, et al. (2015) Mechanical signals promote osteogenic fate through a primary cilia-mediated mechanism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Nguyen AM, Young YN, Jacobs CR. (2015) The primary cilium is a self-adaptable, integrating nexus for mechanical stimuli and cellular signaling. Biology Open
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