Kento Onishi, Ph.D.

Affiliations: 
2014 Biomedical Engineering University of Toronto, Toronto, ON, Canada 
Area:
Biomedical Engineering, Molecular Biology, Cell Biology
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"Kento Onishi"

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Peter W. Zandstra grad student 2014 University of Toronto
 (Dissecting the Role of the Stem Cell Niche in Driving Conversion Between Pluripotent States.)
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Publications

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Yachie-Kinoshita A, Onishi K, Ostblom J, et al. (2018) Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions. Molecular Systems Biology. 14: e7952
Curtis A, Li DJ, DeVeale B, et al. (2016) Patterning of sharp cellular interfaces with a reconfigurable elastic substrate. Integrative Biology : Quantitative Biosciences From Nano to Macro
Onishi K, Zandstra PW. (2015) LIF signaling in stem cells and development. Development (Cambridge, England). 142: 2230-6
Onishi K, Tonge PD, Nagy A, et al. (2014) Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency. Stem Cell Reports. 3: 156-68
DeVeale B, Brokhman I, Mohseni P, et al. (2013) Oct4 is required ~E7.5 for proliferation in the primitive streak. Plos Genetics. 9: e1003957
Onishi K, Tonge PD, Nagy A, et al. (2012) Microenvironment-mediated reversion of epiblast stem cells by reactivation of repressed JAK-STAT signaling. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 1367-76
Moledina F, Clarke G, Oskooei A, et al. (2012) Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 3264-9
Hewel JA, Liu J, Onishi K, et al. (2010) Synthetic peptide arrays for pathway-level protein monitoring by liquid chromatography-tandem mass spectrometry. Molecular & Cellular Proteomics : McP. 9: 2460-73
Peerani R, Onishi K, Mahdavi A, et al. (2009) Manipulation of signaling thresholds in "engineered stem cell niches" identifies design criteria for pluripotent stem cell screens. Plos One. 4: e6438
Alberti K, Davey RE, Onishi K, et al. (2008) Functional immobilization of signaling proteins enables control of stem cell fate. Nature Methods. 5: 645-50
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