Jonathan D. Holz, Ph.D.

Affiliations: 
2011 School of Medicine and Dentistry University of Rochester, Rochester, NY 
Area:
Toxicology
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"Jonathan Holz"

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J Edward Puzas grad student 2011 Rochester
 (Reactive Oxygen Species Mediate Lead Effects in the Genesis of Osteoarthritis.)
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Publications

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Tsai CH, Chang CY, Lin BZ, et al. (2020) Up-regulation of cofilin-1 in cell senescence associates with morphological change and p27 -mediated growth delay. Aging Cell. e13288
Beier EE, Holz J, Sheu TJ, et al. (2015) Elevated Lifetime Lead Exposure Impedes Osteoclast Activity and Produces an Increase in Bone Mass in Adolescent Mice. Toxicological Sciences : An Official Journal of the Society of Toxicology
Beier EE, Sheu TJ, Dang D, et al. (2015) Heavy Metal Ion Regulation of Gene Expression: MECHANISMS BY WHICH LEAD INHIBITS OSTEOBLASTIC BONE-FORMING ACTIVITY THROUGH MODULATION OF THE Wnt/β-CATENIN SIGNALING PATHWAY. The Journal of Biological Chemistry. 290: 18216-26
Tang D, Xu G, Yang Z, et al. (2014) Biphasic calcium phosphate nano-composite scaffolds reinforced with bioglass provide a synthetic alternative to autografts in a canine tibiofibula defect model. Chinese Medical Journal. 127: 1334-8
Li XF, Xu H, Zhao YJ, et al. (2013) Icariin Augments Bone Formation and Reverses the Phenotypes of Osteoprotegerin-Deficient Mice through the Activation of Wnt/ β -Catenin-BMP Signaling. Evidence-Based Complementary and Alternative Medicine : Ecam. 2013: 652317
Wang J, Wang X, Holz JD, et al. (2013) Runx1 is critical for PTH-induced onset of mesenchymal progenitor cell chondrogenic differentiation. Plos One. 8: e74255
Mi M, Shi S, Li T, et al. (2012) TIMP2 deficient mice develop accelerated osteoarthritis via promotion of angiogenesis upon destabilization of the medial meniscus. Biochemical and Biophysical Research Communications. 423: 366-72
Holz JD, Beier E, Sheu TJ, et al. (2012) Lead induces an osteoarthritis-like phenotype in articular chondrocytes through disruption of TGF-β signaling. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 1760-6
Tong P, Wu C, Jin H, et al. (2011) Gene expression profile of steroid-induced necrosis of femoral head of rats. Calcified Tissue International. 89: 271-84
Yang F, Tang DZ, Cui XJ, et al. (2011) Classic yin and yang tonic formula for osteopenia: study protocol for a randomized controlled trial. Trials. 12: 187
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