Robert J. Nims

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2010-2016 Biomedical Engineering Columbia University, New York, NY 
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"Robert Nims"
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Savadipour A, Nims RJ, Rashidi N, et al. (2023) Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221958120
Nims RJ, Pferdehirt L, Guilak F. (2021) Mechanogenetics: harnessing mechanobiology for cellular engineering. Current Opinion in Biotechnology. 73: 374-379
Klimak M, Nims RJ, Pferdehirt L, et al. (2021) Immunoengineering the next generation of arthritis therapies. Acta Biomaterialia
Lee W, Nims RJ, Savadipour A, et al. (2021) Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis. Proceedings of the National Academy of Sciences of the United States of America. 118
Nims RJ, Pferdehirt L, Ho NB, et al. (2021) A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues. Science Advances. 7
Savadipour A, Nims RJ, Katz DB, et al. (2021) Regulation of chondrocyte biosynthetic activity by dynamic hydrostatic pressure: the role of TRP channels. Connective Tissue Research. 1-13
Zimmerman B, Nims R, Chen A, et al. (2020) Direct Osmotic Pressure Measurements in Articular Cartilage Demonstrate Non-Ideal and Concentration-Dependent Phenomena. Journal of Biomechanical Engineering
Durney KM, Shaeffer CA, Zimmerman BK, et al. (2020) Immature bovine cartilage wear by fatigue failure and delamination. Journal of Biomechanics. 107: 109852
Guang Y, McGrath TM, Klug N, et al. (2019) Combined Experimental Approach and Finite Element Modeling of Small Molecule Transport Through Joint Synovium to Measure Effective Diffusivity. Journal of Biomechanical Engineering
Guilak F, Pferdehirt L, Ross AK, et al. (2019) Designer stem cells: Genome engineering and the next generation of cell-based therapies. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
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