| Year |
Citation |
Score |
| 2024 |
Fotio Y, Mabou Tagne A, Squire E, Lee HL, Phillips CM, Chang K, Ahmed F, Greenberg AS, Villalta SA, Scarfone VM, Spadoni G, Mor M, Piomelli D. NAAA-regulated lipid signaling in monocytes controls the induction of hyperalgesic priming in mice. Nature Communications. 15: 1705. PMID 38402219 DOI: 10.1038/s41467-024-46139-5 |
0.793 |
|
| 2024 |
English A, Uittenbogaard F, Torrens A, Sarroza D, Slaven AVE, Piomelli D, Bruchas MR, Stella N, Land BB. A preclinical model of THC edibles that produces high-dose cannabimimetic responses. Elife. 12. PMID 38214701 DOI: 10.7554/eLife.89867 |
0.485 |
|
| 2023 |
Lee HL, Squire E, Fotio Y, Tagne AM, Lee J, Yoon JJ, Hong Y, Kim LH, Jung KM, Piomelli D. Frequent low-impact exposure to THC during adolescence causes persistent sexually dimorphic alterations in the response to viral infection in mice. Pharmacological Research. 107049. PMID 38159785 DOI: 10.1016/j.phrs.2023.107049 |
0.718 |
|
| 2023 |
Carnevali L, Barbetti M, Fotio Y, Ferlenghi F, Vacondio F, Mor M, Piomelli D, Sgoifo A. Enhancement of peripheral fatty acyl ethanolamide signaling prevents stress-induced social avoidance and anxiety-like behaviors in male rats. Psychopharmacology. PMID 37932554 DOI: 10.1007/s00213-023-06473-w |
0.71 |
|
| 2023 |
Lin L, Jung KM, Lee HL, Le J, Colleluori G, Wood C, Palese F, Squire E, Ramirez J, Su S, Torrens A, Fotio Y, Tang L, Yu C, Yang Q, ... ... Piomelli D, et al. Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood. Cell Metabolism. PMID 37267956 DOI: 10.1016/j.cmet.2023.05.002 |
0.78 |
|
| 2023 |
Fotio Y, Mabou Tagne A, Jung KM, Piomelli D. Fatty acid amide hydrolase inhibition alleviates anxiety-like symptoms in a rat model used to study post-traumatic stress disorder. Psychopharmacology. PMID 37017699 DOI: 10.1007/s00213-023-06358-y |
0.788 |
|
| 2022 |
Mabou Tagne A, Fotio Y, Uppal PS, Piomelli D. Synergistic antinociceptive effects of concomitant NAAA and peripheral FAAH inhibition. Experimental Neurology. 357: 114194. PMID 35932800 DOI: 10.1016/j.expneurol.2022.114194 |
0.801 |
|
| 2022 |
Lee HL, Jung KM, Fotio Y, Squire E, Palese F, Lin L, Torrens A, Ahmed F, Mabou Tagne A, Ramirez J, Su S, Wong CR, Jung DH, Scarfone VM, Nguyen PU, ... ... Piomelli D, et al. Frequent Low-Dose Δ-Tetrahydrocannabinol in Adolescence Disrupts Microglia Homeostasis and Disables Responses to Microbial Infection and Social Stress in Young Adulthood. Biological Psychiatry. PMID 35750512 DOI: 10.1016/j.biopsych.2022.04.017 |
0.765 |
|
| 2022 |
Lin L, Mabou Tagne A, Squire EN, Lee HL, Fotio Y, Ramirez J, Zheng M, Torrens A, Ahmed F, Ramos R, Plikus MV, Piomelli D. Diet-Induced Obesity Disrupts Histamine-Dependent Oleoylethanolamide Signaling in the Mouse Liver. Pharmacology. 1-10. PMID 35691287 DOI: 10.1159/000524753 |
0.781 |
|
| 2022 |
Torrens A, Roy P, Lin L, Vu C, Grimes D, Inshishian VC, Montesinos JS, Ahmed F, Mahler SV, Huestis MA, Das A, Piomelli D. Comparative Pharmacokinetics of Δ-Tetrahydrocannabinol in Adolescent and Adult Male and Female Rats. Cannabis and Cannabinoid Research. PMID 35353551 DOI: 10.1089/can.2021.0205 |
0.303 |
|
| 2021 |
Fotio Y, Jung KM, Palese F, Obenaus A, Tagne AM, Lin L, Rashid TI, Pacheco R, Jullienne A, Ramirez J, Mor M, Spadoni G, Jang C, Hohmann AG, Piomelli D. NAAA-regulated lipid signaling governs the transition from acute to chronic pain. Science Advances. 7: eabi8834. PMID 34678057 DOI: 10.1126/sciadv.abi8834 |
0.728 |
|
| 2021 |
Mabou Tagne A, Fotio Y, Alan Springs Z, Su S, Piomelli D. Frequent Δ- tetrahydrocannabinol exposure during adolescence impairs sociability in adult mice exposed to an aversive painful stimulus. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 53: 19-24. PMID 34358818 DOI: 10.1016/j.euroneuro.2021.07.007 |
0.777 |
|
| 2021 |
Mabou Tagne A, Fotio Y, Ibne Rashid T, Piomelli D. . The Journal of Pharmacology and Experimental Therapeutics. PMID 34183435 DOI: 10.1124/jpet.121.000740 |
0.78 |
|
| 2021 |
Fotio Y, Sasso O, Ciccocioppo R, Piomelli D. . The Journal of Pharmacology and Experimental Therapeutics. PMID 33986036 DOI: 10.1124/jpet.121.000674 |
0.789 |
|
| 2021 |
Tagne AM, Fotio Y, Lin L, Squire E, Ahmed F, Rashid TI, Azari EK, Piomelli D. Palmitoylethanolamide and hemp oil extract exert synergistic anti-nociceptive effects in mouse models of acute and chronic pain. Pharmacological Research. 105545. PMID 33722712 DOI: 10.1016/j.phrs.2021.105545 |
0.737 |
|
| 2021 |
Pai AY, Wenziger C, Streja E, Argueta DA, DiPatrizio NV, Rhee CM, Vaziri ND, Kalantar-Zadeh K, Piomelli D, Moradi H. Impact of Circulating N-Acylethanolamine Levels with Clinical and Laboratory End Points in Hemodialysis Patients. American Journal of Nephrology. 1-10. PMID 33601382 DOI: 10.1159/000513381 |
0.621 |
|
| 2021 |
Jung KM, Lin L, Piomelli D. The endocannabinoid system in the adipose organ. Reviews in Endocrine & Metabolic Disorders. PMID 33387286 DOI: 10.1007/s11154-020-09623-z |
0.371 |
|
| 2020 |
Fotio Y, Ciccocioppo R, Piomelli D. N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats. Psychopharmacology. PMID 33037452 DOI: 10.1007/s00213-020-05678-7 |
0.784 |
|
| 2020 |
Ruiz CM, Torrens A, Castillo E, Perrone CR, Cevallos J, Inshishian VC, Harder EV, Justeson DN, Huestis MA, Swarup V, Piomelli D, Mahler SV. Pharmacokinetic, behavioral, and brain activity effects of Δ-tetrahydrocannabinol in adolescent male and female rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32927465 DOI: 10.1038/S41386-020-00839-W |
0.303 |
|
| 2020 |
Pontis S, Palese F, Summa M, Realini N, Lanfranco M, De Mei C, Piomelli D. N-Acylethanolamine Acid Amidase contributes to disease progression in a mouse model of multiple sclerosis. Pharmacological Research. 160: 105064. PMID 32634582 DOI: 10.1016/j.phrs.2020.105064 |
0.341 |
|
| 2020 |
Ivy D, Palese F, Vozella V, Fotio Y, Yalcin A, Ramirez G, Mears D, Wynn G, Piomelli D. Cannabinoid CB receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32375160 DOI: 10.1038/s41386-020-0696-x |
0.766 |
|
| 2020 |
Torrens A, Vozella V, Huff H, McNeil B, Ahmed F, Ghidini A, Mahler SV, Huestis MA, Das A, Piomelli D. Comparative Pharmacokinetics of Δ-Tetrahydrocannabinol in Adolescent and Adult Male Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 32345621 DOI: 10.1124/Jpet.120.265892 |
0.783 |
|
| 2020 |
Carloni S, Crinelli R, Palma L, Alvarez FJ, Piomelli D, Duranti A, Balduini W, Alonso-Alconada D. The Synthetic Cannabinoid URB447 Reduces Brain Injury and the Associated White Matter Demyelination After Hypoxia-Ischemia in Neonatal Rats. Acs Chemical Neuroscience. PMID 32271539 DOI: 10.1021/Acschemneuro.0C00047 |
0.331 |
|
| 2020 |
Piomelli D, Scalvini L, Fotio Y, Lodola A, Spadoni G, Tarzia G, Mor M. N-acylethanolamine Acid Amidase (NAAA): Structure, Functions and Inhibition. Journal of Medicinal Chemistry. PMID 32191459 DOI: 10.1021/Acs.Jmedchem.0C00191 |
0.756 |
|
| 2020 |
Fotio Y, Palese F, Guaman Tipan P, Ahmed F, Piomelli D. Fatty acid amide hydrolase inhibition in the central nervous system prevents and reverses morphine tolerance in male and female mice. British Journal of Pharmacology. PMID 32077093 DOI: 10.1111/bph.15031 |
0.764 |
|
| 2020 |
Macías-Triana L, Romero-Cordero K, Tatum-Kuri A, Vera-Barrón A, Millán-Aldaco D, Arankowsky-Sandoval G, Piomelli D, Murillo-Rodríguez E. Exposure to the cannabinoid agonist WIN 55, 212-2 in adolescent rats causes sleep alterations that persist until adulthood. European Journal of Pharmacology. 874: 172911. PMID 32045604 DOI: 10.1016/J.Ejphar.2020.172911 |
0.586 |
|
| 2020 |
Moradi H, Park C, Streja E, Argueta DA, DiPatrizio NV, You AS, Rhee CM, Vaziri ND, Kalantar-Zadeh K, Piomelli D. Circulating Endocannabinoids and Mortality in Hemodialysis Patients. American Journal of Nephrology. 1-10. PMID 31935741 DOI: 10.1159/000505444 |
0.603 |
|
| 2019 |
Castelli R, Scalvini L, Vacondio F, Lodola A, Anselmi M, Vezzosi S, Carmi C, Bassi M, Ferlenghi F, Rivara S, Möller IR, Rand KD, Daglian J, Wei D, Dotsey EY, ... ... Piomelli D, et al. Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteines. Journal of Medicinal Chemistry. PMID 31714779 DOI: 10.1021/Acs.Jmedchem.9B01679 |
0.794 |
|
| 2019 |
Palese F, Pontis S, Realini N, Piomelli D. A protective role for N-acylphosphatidylethanolamine phospholipase D in 6-OHDA-induced neurodegeneration. Scientific Reports. 9: 15927. PMID 31685899 DOI: 10.1038/s41598-019-51799-1 |
0.315 |
|
| 2019 |
Greco R, Demartini C, Zanaboni AM, Tumelero E, Reggiani A, Misto A, Piomelli D, Tassorelli C. FAAH inhibition as a preventive treatment for migraine: A pre-clinical study. Neurobiology of Disease. 134: 104624. PMID 31629892 DOI: 10.1016/j.nbd.2019.104624 |
0.365 |
|
| 2019 |
Moradi H, Park C, Igarashi M, Streja E, Argueta DA, Soohoo M, Daglian J, You AS, Rhee CM, Kashyap ML, DiPatrizio NV, Vaziri ND, Kalantar-Zadeh K, Piomelli D. Serum Endocannabinoid Levels in Patients With End-Stage Renal Disease. Journal of the Endocrine Society. 3: 1869-1880. PMID 31583368 DOI: 10.1210/Js.2019-00242 |
0.625 |
|
| 2019 |
Vozella V, Ahmed F, Choobchian P, Merrill CB, Zibardi C, Tarzia G, Mor M, Duranti A, Tontini A, Rivara S, Piomelli D. Pharmacokinetics, pharmacodynamics and safety studies on URB937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats. The Journal of Pharmacy and Pharmacology. PMID 31579946 DOI: 10.1111/Jphp.13166 |
0.343 |
|
| 2019 |
Vozella V, Realini N, Misto A, Piomelli D. Feeding Stimulates Sphingosine-1-Phosphate Mobilization in Mouse Hypothalamus. International Journal of Molecular Sciences. 20. PMID 31426457 DOI: 10.3390/ijms20164008 |
0.307 |
|
| 2019 |
Gómez-Boronat M, Isorna E, Armirotti A, Delgado MJ, Piomelli D, de Pedro N. Diurnal Profiles of -Acylethanolamines in Goldfish Brain and Gastrointestinal Tract: Possible Role of Feeding. Frontiers in Neuroscience. 13: 450. PMID 31133788 DOI: 10.3389/fnins.2019.00450 |
0.344 |
|
| 2018 |
Misto A, Provensi G, Vozella V, Passani MB, Piomelli D. Mast Cell-Derived Histamine Regulates Liver Ketogenesis via Oleoylethanolamide Signaling. Cell Metabolism. PMID 30318340 DOI: 10.1016/j.cmet.2018.09.014 |
0.348 |
|
| 2018 |
Gorelik A, Gebai A, Illes K, Piomelli D, Nagar B. Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proceedings of the National Academy of Sciences of the United States of America. PMID 30301806 DOI: 10.1073/Pnas.1811759115 |
0.352 |
|
| 2018 |
Danandeh A, Vozella V, Lim J, Oveisi F, Ramirez GL, Mears D, Wynn G, Piomelli D. Effects of fatty acid amide hydrolase inhibitor URB597 in a rat model of trauma-induced long-term anxiety. Psychopharmacology. PMID 30251159 DOI: 10.1007/s00213-018-5020-7 |
0.347 |
|
| 2018 |
Spadoni G, Bedini A, Furiassi L, Mari M, Mor M, Scalvini L, Lodola A, Ghidini A, Lucini V, Dugnani S, Scaglione F, Piomelli D, Jung KM, Supuran CT, Lucarini L, et al. Identification of bivalent ligands with melatonin receptor agonist and fatty acid amide hydrolase (FAAH) inhibitory activity that exhibit ocular hypotensive effect in the rabbit. Journal of Medicinal Chemistry. PMID 30126274 DOI: 10.1021/Acs.Jmedchem.8B00893 |
0.364 |
|
| 2018 |
Greco R, Demartini C, Zanaboni AM, Piomelli D, Tassorelli C. Endocannabinoid System and Migraine Pain: An Update. Frontiers in Neuroscience. 12: 172. PMID 29615860 DOI: 10.3389/fnins.2018.00172 |
0.377 |
|
| 2018 |
Koethe D, Pahlisch F, Hellmich M, Rohleder C, Mueller JK, Meyer-Lindenberg A, Torrey EF, Piomelli D, Leweke FM. Familial Abnormalities of Endocannabinoid Signaling in Schizophrenia. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-26. PMID 29521179 DOI: 10.1080/15622975.2018.1449966 |
0.505 |
|
| 2018 |
Goodman MC, Xu S, Rouzer CA, Banerjee S, Ghebreselasie K, Migliore M, Piomelli D, Marnett LJ. Dual cyclooxygenase-fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site. The Journal of Biological Chemistry. PMID 29326169 DOI: 10.1074/jbc.M117.802058 |
0.344 |
|
| 2017 |
Sasso O, Summa M, Armirotti A, Pontis S, De Mei C, Piomelli D. The N-acylethanolamine acid amidase inhibitor ARN077 suppresses inflammation and pruritus in a mouse model of allergic dermatitis. The Journal of Investigative Dermatology. PMID 29054595 DOI: 10.1016/j.jid.2017.07.853 |
0.373 |
|
| 2017 |
Petracca R, Romeo E, Baggelaar MP, Artola M, Pontis S, Ponzano S, Overkleeft HS, van der Stelt M, Piomelli D. Novel activity-based probes for N-acylethanolamine acid amidase. Chemical Communications (Cambridge, England). PMID 29035406 DOI: 10.1039/C7Cc06838G |
0.32 |
|
| 2017 |
Angelini R, Argueta DA, Piomelli D, DiPatrizio NV. Identification of a Widespread Palmitoylethanolamide Contamination in Standard Laboratory Glassware. Cannabis and Cannabinoid Research. 2: 123-132. PMID 28861512 DOI: 10.1089/can.2017.0019 |
0.584 |
|
| 2017 |
Vozella V, Basit A, Misto A, Piomelli D. Age-dependent changes in nervonic acid-containing sphingolipids in mouse hippocampus. Biochimica Et Biophysica Acta. PMID 28855145 DOI: 10.1016/j.bbalip.2017.08.008 |
0.312 |
|
| 2017 |
Greco R, Demartini C, Zanaboni AM, Berliocchi L, Piomelli D, Tassorelli C. Inhibition of monoacylglycerol lipase: Another signalling pathway for potential therapeutic targets in migraine? Cephalalgia : An International Journal of Headache. 333102417727537. PMID 28816506 DOI: 10.1177/0333102417727537 |
0.37 |
|
| 2017 |
Rock EM, Moreno-Sanz G, Limebeer CL, Petrie GN, Angelini R, Piomelli D, Parker LA. Suppression of acute and anticipatory nausea by peripherally restricted FAAH inhibitor in animal models: Role of PPARα and CB1 receptors. British Journal of Pharmacology. PMID 28805944 DOI: 10.1111/Bph.13980 |
0.38 |
|
| 2017 |
Khurana L, Mackie K, Piomelli D, Kendall DA. Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities. Neuropharmacology. PMID 28527758 DOI: 10.1016/J.Neuropharm.2017.05.018 |
0.541 |
|
| 2017 |
Marrone MC, Morabito A, Giustizieri M, Chiurchiù V, Leuti A, Mattioli M, Marinelli S, Riganti L, Lombardi M, Murana E, Totaro A, Piomelli D, Ragozzino D, Oddi S, Maccarrone M, et al. TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice. Nature Communications. 8: 15292. PMID 28489079 DOI: 10.1038/ncomms15292 |
0.328 |
|
| 2017 |
Mangieri R, Aziz H, Piomelli D, Morrisett R. Inhibition of N-acylethanolamine acid amidase reverses effects of chronic binge ethanol drinking on ventral tegmental area dopamine neuron firing Alcohol. 60: 240. DOI: 10.1016/j.alcohol.2017.02.340 |
0.682 |
|
| 2016 |
Igarashi M, Narayanaswami V, Kimonis V, Galassetti PM, Oveisi F, Jung KM, Piomelli D. Dysfunctional oleoylethanolamide signaling in a mouse model of Prader-Willi syndrome. Pharmacological Research. PMID 28007570 DOI: 10.1016/J.Phrs.2016.12.024 |
0.337 |
|
| 2016 |
Petracca R, Ponzano S, Bertozzi SM, Sasso O, Piomelli D, Bandiera T, Bertozzi F. Progress in the development of β-lactams as N-Acylethanolamine Acid Amidase (NAAA) inhibitors: Synthesis and SAR study of new, potent N-O-substituted derivatives. European Journal of Medicinal Chemistry. 126: 561-575. PMID 27915171 DOI: 10.1016/j.ejmech.2016.11.039 |
0.342 |
|
| 2016 |
Romeo E, Pontis S, Ponzano S, Bonezzi F, Migliore M, Di Martino S, Summa M, Piomelli D. Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase. Journal of Visualized Experiments : Jove. PMID 27911411 DOI: 10.3791/54652 |
0.315 |
|
| 2016 |
Margheritis E, Castellani B, Magotti P, Peruzzi S, Romeo E, Natali F, Mostarda S, Gioiello A, Piomelli D, Garau G. Bile Acid Recognition by NAPE-PLD. Acs Chemical Biology. PMID 27571266 DOI: 10.1021/Acschembio.6B00624 |
0.357 |
|
| 2016 |
Wang W, Trieu BH, Palmer LC, Jia Y, Pham DT, Jung KM, Karsten CA, Merrill CB, Mackie K, Gall CM, Piomelli D, Lynch G. A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation. Eneuro. 3. PMID 27517090 DOI: 10.1523/ENEURO.0160-16.2016 |
0.462 |
|
| 2016 |
Sasso O, Pontis S, Armirotti A, Cardinali G, Kovacs D, Migliore M, Summa M, Moreno-Sanz G, Picardo M, Piomelli D. Endogenous N-acyl taurines regulate skin wound healing. Proceedings of the National Academy of Sciences of the United States of America. PMID 27412859 DOI: 10.1073/pnas.1605578113 |
0.316 |
|
| 2016 |
Migliore M, Pontis S, Fuentes de Arriba AL, Realini N, Torrente E, Armirotti A, Romeo E, Di Martino S, Russo D, Pizzirani D, Summa M, Lanfranco M, Ottonello G, Busquet P, Jung KM, ... ... Piomelli D, et al. Second-Generation Non-Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis. Angewandte Chemie (International Ed. in English). PMID 27404798 DOI: 10.1002/anie.201603746 |
0.337 |
|
| 2016 |
Wang H, Taussig MD, DiPatrizio NV, Bruce K, Piomelli D, Eckel RH. Obesity development in neuron-specific lipoprotein lipase deficient mice is not responsive to increased dietary fat content or change in fat composition. Metabolism: Clinical and Experimental. 65: 987-97. PMID 27282869 DOI: 10.1016/J.Metabol.2016.01.015 |
0.645 |
|
| 2016 |
Jung KM, Piomelli D. Assay of Monoacylglycerol Lipase Activity. Methods in Molecular Biology (Clifton, N.J.). 1412: 157-68. PMID 27245902 DOI: 10.1007/978-1-4939-3539-0_17 |
0.339 |
|
| 2016 |
Jacome-Sosa M, Vacca C, Mangat R, Diane A, Nelson RC, Reaney MJ, Shen J, Curtis JM, Vine DF, Field CJ, Igarashi M, Piomelli D, Banni S, Proctor SD. Vaccenic acid suppresses intestinal inflammation by increasing the endocannabinoid anandamide and non-cannabinoid signaling molecules in a rat model of the metabolic syndrome. Journal of Lipid Research. PMID 26891736 DOI: 10.1194/jlr.M066308 |
0.363 |
|
| 2016 |
Brindisi M, Maramai S, Gemma S, Brogi S, Grillo A, Di Cesare Mannelli L, Gabellieri E, Lamponi S, Saponara S, Gorelli B, Tedesco D, Bonfiglio T, Landry C, Jung KM, Armirotti A, ... ... Piomelli D, et al. Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain. Journal of Medicinal Chemistry. PMID 26888301 DOI: 10.1021/Acs.Jmedchem.5B01812 |
0.332 |
|
| 2016 |
Wei D, Lee D, Li D, Daglian J, Jung KM, Piomelli D. A role for the endocannabinoid 2-arachidonoyl-sn-glycerol for social and high-fat food reward in male mice. Psychopharmacology. PMID 26873082 DOI: 10.1007/s00213-016-4222-0 |
0.326 |
|
| 2016 |
Nuzzi A, Fiasella A, Ortega JA, Pagliuca C, Ponzano S, Pizzirani D, Bertozzi SM, Ottonello G, Tarozzo G, Reggiani A, Bandiera T, Bertozzi F, Piomelli D. Potent α-amino-β-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure-activity relationship (SAR) studies. European Journal of Medicinal Chemistry. 111: 138-159. PMID 26866968 DOI: 10.1016/j.ejmech.2016.01.046 |
0.346 |
|
| 2016 |
Bonezzi F, Sasso O, Pontis S, Realini N, Romeo E, Ponzano S, Nuzzi A, Fiasella A, Bertozzi F, Piomelli D. An Important role for N-Acylethanolamine Acid Amidase in the Complete Freund's Adjuvant Rat Model of Arthritis. The Journal of Pharmacology and Experimental Therapeutics. PMID 26769918 DOI: 10.1124/jpet.115.230516 |
0.369 |
|
| 2016 |
Piomelli D, Diamanti E, Bottegoni G, Goldoni L, Realini N, Pagliuca C, Bertozzi F, Pizzirani D. Pyrazole-Based Acid Ceramidase Inhibitors: Design, Synthesis, and Structure–Activity Relationships Synthesis. 48: 2739-2756. DOI: 10.1055/S-0035-1561456 |
0.323 |
|
| 2015 |
Migliore M, Habrant D, Sasso O, Albani C, Bertozzi SM, Armirotti A, Piomelli D, Scarpelli R. Potent multitarget FAAH-COX inhibitors: Design and structure-activity relationship studies. European Journal of Medicinal Chemistry. 109: 216-237. PMID 26774927 DOI: 10.1016/j.ejmech.2015.12.036 |
0.348 |
|
| 2015 |
Pontis S, Ribeiro A, Sasso O, Piomelli D. Macrophage-derived lipid agonists of PPAR-α as intrinsic controllers of inflammation. Critical Reviews in Biochemistry and Molecular Biology. 1-8. PMID 26585314 DOI: 10.3109/10409238.2015.1092944 |
0.346 |
|
| 2015 |
Bach A, Pizzirani D, Realini N, Vozella V, Russo D, Penna I, Melzig L, Scarpelli R, Piomelli D. Benzoxazolone Carboxamides as Potent Acid Ceramidase Inhibitors: Synthesis and Structure-Activity Relationship (SAR) Studies. Journal of Medicinal Chemistry. PMID 26560855 DOI: 10.1021/acs.jmedchem.5b01188 |
0.365 |
|
| 2015 |
Panlilio LV, Thorndike EB, Nikas SP, Alapafuja SO, Bandiera T, Cravatt BF, Makriyannis A, Piomelli D, Goldberg SR, Justinova Z. Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats. Psychopharmacology. PMID 26558620 DOI: 10.1007/S00213-015-4140-6 |
0.344 |
|
| 2015 |
Realini N, Palese F, Pizzirani D, Pontis S, Basit A, Bach A, Ganesan A, Piomelli D. Acid Ceramidase in Melanoma: Expression, Localization and Effects of Pharmacological Inhibition. The Journal of Biological Chemistry. PMID 26553872 DOI: 10.1074/jbc.M115.666909 |
0.3 |
|
| 2015 |
Wei D, Lee D, Cox CD, Karsten CA, Peñagarikano O, Geschwind DH, Gall CM, Piomelli D. Endocannabinoid signaling mediates oxytocin-driven social reward. Proceedings of the National Academy of Sciences of the United States of America. PMID 26504214 DOI: 10.1073/Pnas.1509795112 |
0.303 |
|
| 2015 |
Scarpelli R, Sasso O, Piomelli D. A Double Whammy: Targeting Both Fatty Acid Amide Hydrolase (FAAH) and Cyclooxygenase (COX) To Treat Pain and Inflammation. Chemmedchem. PMID 26486424 DOI: 10.1002/cmdc.201500395 |
0.341 |
|
| 2015 |
Lim J, Igarashi M, Jung KM, Butini S, Campiani G, Piomelli D. Endocannabinoid Modulation of Predator Stress-Induced Long-Term Anxiety in Rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26361059 DOI: 10.1038/Npp.2015.284 |
0.338 |
|
| 2015 |
DiPatrizio NV, Igarashi M, Narayanaswami V, Murray C, Gancayco J, Russell A, Jung KM, Piomelli D. Fasting stimulates 2-AG biosynthesis in the small intestine: role of cholinergic pathways. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00239.2015. PMID 26290104 DOI: 10.1152/Ajpregu.00239.2015 |
0.677 |
|
| 2015 |
Yu T, Taussig MD, DiPatrizio NV, Astarita G, Piomelli D, Bergman BC, Dell'Acqua ML, Eckel RH, Wang H. Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice. Plos One. 10: e0135113. PMID 26263173 DOI: 10.1371/Journal.Pone.0135113 |
0.674 |
|
| 2015 |
Scalvini L, Piomelli D, Mor M. Monoglyceride lipase: Structure and inhibitors. Chemistry and Physics of Lipids. PMID 26216043 DOI: 10.1016/j.chemphyslip.2015.07.011 |
0.315 |
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| 2015 |
Romeo E, Ponzano S, Armirotti A, Summa M, Bertozzi F, Garau G, Bandiera T, Piomelli D. Activity-Based Probe for N-Acylethanolamine Acid Amidase. Acs Chemical Biology. 10: 2057-64. PMID 26102511 DOI: 10.1021/acschembio.5b00197 |
0.375 |
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| 2015 |
Bilbao A, Serrano A, Cippitelli A, Pavón FJ, Giuffrida A, Suárez J, García-Marchena N, Baixeras E, Gómez de Heras R, Orio L, Alén F, Ciccocioppo R, Cravatt BF, Parsons LH, Piomelli D, et al. Role of the satiety factor oleoylethanolamide in alcoholism. Addiction Biology. PMID 26037332 DOI: 10.1111/Adb.12276 |
0.605 |
|
| 2015 |
Igarashi M, DiPatrizio NV, Narayanaswami V, Piomelli D. Feeding-induced oleoylethanolamide mobilization is disrupted in the gut of diet-induced obese rodents. Biochimica Et Biophysica Acta. 1851: 1218-26. PMID 26024927 DOI: 10.1016/J.Bbalip.2015.05.006 |
0.653 |
|
| 2015 |
Dotsey EY, Jung KM, Basit A, Wei D, Daglian J, Vacondio F, Armirotti A, Mor M, Piomelli D. Peroxide-Dependent MGL Sulfenylation Regulates 2-AG-Mediated Endocannabinoid Signaling in Brain Neurons. Chemistry & Biology. 22: 619-28. PMID 26000748 DOI: 10.1016/J.Chembiol.2015.04.013 |
0.789 |
|
| 2015 |
Sasso O, Wagner K, Morisseau C, Inceoglu B, Hammock BD, Piomelli D. Peripheral FAAH and soluble epoxide hydrolase inhibitors are synergistically antinociceptive. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 97: 7-15. PMID 25882247 DOI: 10.1016/J.Phrs.2015.04.001 |
0.381 |
|
| 2015 |
Ribeiro A, Pontis S, Mengatto L, Armirotti A, Chiurchiù V, Capurro V, Fiasella A, Nuzzi A, Romeo E, Moreno-Sanz G, Maccarrone M, Reggiani A, Tarzia G, Mor M, Bertozzi F, ... ... Piomelli D, et al. A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation. Acs Chemical Biology. PMID 25874594 DOI: 10.1021/Acschembio.5B00114 |
0.371 |
|
| 2015 |
Sasso O, Migliore M, Habrant D, Armirotti A, Albani C, Summa M, Moreno-Sanz G, Scarpelli R, Piomelli D. Multitarget fatty acid amide hydrolase/cyclooxygenase blockade suppresses intestinal inflammation and protects against nonsteroidal anti-inflammatory drug-dependent gastrointestinal damage. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2616-27. PMID 25757568 DOI: 10.1096/fj.15-270637 |
0.326 |
|
| 2015 |
Justinova Z, Panlilio LV, Moreno-Sanz G, Redhi GH, Auber A, Secci ME, Mascia P, Bandiera T, Armirotti A, Bertorelli R, Chefer SI, Barnes C, Yasar S, Piomelli D, Goldberg SR. Effects of Fatty Acid Amide Hydrolase (FAAH) Inhibitors in Non-Human Primate Models of Nicotine Reward and Relapse. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 2185-97. PMID 25754762 DOI: 10.1038/npp.2015.62 |
0.323 |
|
| 2015 |
Niki M, Jyotaki M, Yoshida R, Yasumatsu K, Shigemura N, DiPatrizio NV, Piomelli D, Ninomiya Y. Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice. The Journal of Physiology. 593: 2527-45. PMID 25728242 DOI: 10.1113/JP270295 |
0.662 |
|
| 2015 |
Magotti P, Bauer I, Igarashi M, Babagoli M, Marotta R, Piomelli D, Garau G. Structure of human N-acylphosphatidylethanolamine-hydrolyzing phospholipase D: regulation of fatty acid ethanolamide biosynthesis by bile acids. Structure (London, England : 1993). 23: 598-604. PMID 25684574 DOI: 10.1016/j.str.2014.12.018 |
0.355 |
|
| 2015 |
Astarita G, Avanesian A, Grimaldi B, Realini N, Justinova Z, Panlilio LV, Basit A, Goldberg SR, Piomelli D. Methamphetamine accelerates cellular senescence through stimulation of de novo ceramide biosynthesis. Plos One. 10: e0116961. PMID 25671639 DOI: 10.1371/Journal.Pone.0116961 |
0.355 |
|
| 2015 |
DiPatrizio NV, Piomelli D. Intestinal lipid-derived signals that sense dietary fat. The Journal of Clinical Investigation. 125: 891-8. PMID 25642767 DOI: 10.1172/JCI76302 |
0.642 |
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| 2015 |
Greco R, Bandiera T, Mangione A, Demartini C, Siani F, Nappi G, Sandrini G, Guijarro A, Armirotti A, Piomelli D, Tassorelli C. Effects of peripheral FAAH blockade on NTG-induced hyperalgesia-evaluation of URB937 in an animal model of migraine. Cephalalgia : An International Journal of Headache. PMID 25608877 DOI: 10.1177/0333102414566862 |
0.371 |
|
| 2015 |
Pizzirani D, Bach A, Realini N, Armirotti A, Mengatto L, Bauer I, Girotto S, Pagliuca C, De Vivo M, Summa M, Ribeiro A, Piomelli D. Benzoxazolone carboxamides: potent and systemically active inhibitors of intracellular acid ceramidase. Angewandte Chemie (International Ed. in English). 54: 485-9. PMID 25395373 DOI: 10.1002/anie.201410931 |
0.355 |
|
| 2015 |
Colombano G, Albani C, Ottonello G, Ribeiro A, Scarpelli R, Tarozzo G, Daglian J, Jung KM, Piomelli D, Bandiera T. O-(triazolyl)methyl carbamates as a novel and potent class of fatty acid amide hydrolase (FAAH) inhibitors. Chemmedchem. 10: 380-95. PMID 25338703 DOI: 10.1002/cmdc.201402374 |
0.341 |
|
| 2015 |
Igarashi M, DiPatrizio NV, Narayanaswami V, Piomelli D. Feeding-induced oleoylethanolamide mobilization is disrupted in the gut of diet-induced obese rodents Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1851: 1218-1226. DOI: 10.1016/j.bbalip.2015.05.006 |
0.585 |
|
| 2014 |
Piomelli D, Hohmann AG, Seybold V, Hammock BD. A lipid gate for the peripheral control of pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15184-91. PMID 25392487 DOI: 10.1523/Jneurosci.3475-14.2014 |
0.373 |
|
| 2014 |
Ponzano S, Berteotti A, Petracca R, Vitale R, Mengatto L, Bandiera T, Cavalli A, Piomelli D, Bertozzi F, Bottegoni G. Synthesis, biological evaluation, and 3D QSAR study of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters as N-acylethanolamine acid amidase (NAAA) inhibitors. Journal of Medicinal Chemistry. 57: 10101-11. PMID 25380517 DOI: 10.1021/jm501455s |
0.326 |
|
| 2014 |
Moreno-Sanz G, Barrera B, Armirotti A, Bertozzi SM, Scarpelli R, Bandiera T, Prieto JG, Duranti A, Tarzia G, Merino G, Piomelli D. Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 87: 87-93. PMID 24993496 DOI: 10.1016/J.Phrs.2014.06.004 |
0.34 |
|
| 2014 |
Piomelli D. A mighty (ochondrial) fight? Molecular Metabolism. 3: 345-6. PMID 24944892 DOI: 10.1016/j.molmet.2014.04.005 |
0.338 |
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| 2014 |
Tinoco AB, Armirotti A, Isorna E, Delgado MJ, Piomelli D, de Pedro N. Role of oleoylethanolamide as a feeding regulator in goldfish. The Journal of Experimental Biology. 217: 2761-9. PMID 24855680 DOI: 10.1242/jeb.106161 |
0.32 |
|
| 2014 |
Fiasella A, Nuzzi A, Summa M, Armirotti A, Tarozzo G, Tarzia G, Mor M, Bertozzi F, Bandiera T, Piomelli D. 3-Aminoazetidin-2-one derivatives as N-acylethanolamine acid amidase (NAAA) inhibitors suitable for systemic administration. Chemmedchem. 9: 1602-14. PMID 24828120 DOI: 10.1002/Cmdc.201300546 |
0.375 |
|
| 2014 |
Bandiera T, Ponzano S, Piomelli D. Advances in the discovery of N-acylethanolamine acid amidase inhibitors. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 86: 11-7. PMID 24798679 DOI: 10.1016/j.phrs.2014.04.011 |
0.403 |
|
| 2014 |
De Simone A, Ruda GF, Albani C, Tarozzo G, Bandiera T, Piomelli D, Cavalli A, Bottegoni G. Applying a multitarget rational drug design strategy: the first set of modulators with potent and balanced activity toward dopamine D3 receptor and fatty acid amide hydrolase. Chemical Communications (Cambridge, England). 50: 4904-7. PMID 24691497 DOI: 10.1039/c4cc00967c |
0.355 |
|
| 2014 |
Piomelli D. A discount on cannabinoids. Biological Psychiatry. 75: 432-4. PMID 24560432 DOI: 10.1016/j.biopsych.2014.01.010 |
0.311 |
|
| 2014 |
Piomelli D, Sasso O. Peripheral gating of pain signals by endogenous lipid mediators. Nature Neuroscience. 17: 164-74. PMID 24473264 DOI: 10.1038/nn.3612 |
0.328 |
|
| 2014 |
Sahar S, Masubuchi S, Eckel-Mahan K, Vollmer S, Galla L, Ceglia N, Masri S, Barth TK, Grimaldi B, Oluyemi O, Astarita G, Hallows WC, Piomelli D, Imhof A, Baldi P, et al. Circadian control of fatty acid elongation by SIRT1 protein-mediated deacetylation of acetyl-coenzyme A synthetase 1. The Journal of Biological Chemistry. 289: 6091-7. PMID 24425865 DOI: 10.1074/Jbc.M113.537191 |
0.308 |
|
| 2014 |
Vitale R, Ottonello G, Petracca R, Bertozzi SM, Ponzano S, Armirotti A, Berteotti A, Dionisi M, Cavalli A, Piomelli D, Bandiera T, Bertozzi F. Synthesis, structure-activity, and structure-stability relationships of 2-substituted-N-(4-oxo-3-oxetanyl) N-acylethanolamine acid amidase (NAAA) inhibitors. Chemmedchem. 9: 323-36. PMID 24403170 DOI: 10.1002/cmdc.201300416 |
0.346 |
|
| 2014 |
Iorio M, Sasso O, Maffioli SI, Bertorelli R, Monciardini P, Sosio M, Bonezzi F, Summa M, Brunati C, Bordoni R, Corti G, Tarozzo G, Piomelli D, Reggiani A, Donadio S. A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity. Acs Chemical Biology. 9: 398-404. PMID 24191663 DOI: 10.1021/cb400692w |
0.329 |
|
| 2014 |
Piomelli D. More surprises lying ahead. The endocannabinoids keep us guessing. Neuropharmacology. 76: 228-34. PMID 23954677 DOI: 10.1016/j.neuropharm.2013.07.026 |
0.364 |
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| 2014 |
Greco R, Bandiera T, Mangione A, Siani F, Nappi G, Sandrini G, Guijarro A, Armirotti A, Piomelli D, Tassorelli C. EHMTI-0141. URB937 as a potential therapeutic option for migraine: evaluation in animal model of migraine The Journal of Headache and Pain. 15. DOI: 10.1186/1129-2377-15-S1-F27 |
0.345 |
|
| 2014 |
Pizzirani D, Bach A, Realini N, Armirotti A, Mengatto L, Bauer I, Girotto S, Pagliuca C, De Vivo M, Summa M, Ribeiro A, Piomelli D. Innentitelbild: Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase (Angew. Chem. 2/2015) Angewandte Chemie. 127: 374-374. DOI: 10.1002/ange.201410931 |
0.316 |
|
| 2013 |
Palermo G, Campomanes P, Neri M, Piomelli D, Cavalli A, Rothlisberger U, De Vivo M. Wagging the Tail: Essential Role of Substrate Flexibility in FAAH Catalysis. Journal of Chemical Theory and Computation. 9: 1202-13. PMID 26588763 DOI: 10.1021/Ct300611Q |
0.312 |
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| 2013 |
Ponzano S, Bertozzi F, Mengatto L, Dionisi M, Armirotti A, Romeo E, Berteotti A, Fiorelli C, Tarozzo G, Reggiani A, Duranti A, Tarzia G, Mor M, Cavalli A, Piomelli D, et al. Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors. Journal of Medicinal Chemistry. 56: 6917-34. PMID 23991897 DOI: 10.1021/Jm400739U |
0.371 |
|
| 2013 |
O'Brien LD, Limebeer CL, Rock EM, Bottegoni G, Piomelli D, Parker LA. Anandamide transport inhibition by ARN272 attenuates nausea-induced behaviour in rats, and vomiting in shrews (Suncus murinus). British Journal of Pharmacology. 170: 1130-6. PMID 23991698 DOI: 10.1111/Bph.12360 |
0.339 |
|
| 2013 |
Moreno-Sanz G, Duranti A, Melzig L, Fiorelli C, Ruda GF, Colombano G, Mestichelli P, Sanchini S, Tontini A, Mor M, Bandiera T, Scarpelli R, Tarzia G, Piomelli D. Synthesis and structure-activity relationship studies of O-biphenyl-3-yl carbamates as peripherally restricted fatty acid amide hydrolase inhibitors. Journal of Medicinal Chemistry. 56: 5917-30. PMID 23822179 DOI: 10.1021/Jm4007017 |
0.384 |
|
| 2013 |
Pizzirani D, Pagliuca C, Realini N, Branduardi D, Bottegoni G, Mor M, Bertozzi F, Scarpelli R, Piomelli D, Bandiera T. Discovery of a new class of highly potent inhibitors of acid ceramidase: synthesis and structure-activity relationship (SAR). Journal of Medicinal Chemistry. 56: 3518-30. PMID 23614460 DOI: 10.1021/jm301879g |
0.327 |
|
| 2013 |
Piomelli D. A fatty gut feeling. Trends in Endocrinology and Metabolism: Tem. 24: 332-41. PMID 23567058 DOI: 10.1016/j.tem.2013.03.001 |
0.361 |
|
| 2013 |
Lopes JP, Tarozzo G, Reggiani A, Piomelli D, Cavalli A. Galantamine potentiates the neuroprotective effect of memantine against NMDA-induced excitotoxicity. Brain and Behavior. 3: 67-74. PMID 23532860 DOI: 10.1002/brb3.118 |
0.307 |
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| 2013 |
DiPatrizio NV, Joslin A, Jung KM, Piomelli D. Endocannabinoid signaling in the gut mediates preference for dietary unsaturated fats. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2513-20. PMID 23463697 DOI: 10.1096/fj.13-227587 |
0.67 |
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| 2013 |
Lodola A, Capoferri L, Rivara S, Tarzia G, Piomelli D, Mulholland A, Mor M. Quantum mechanics/molecular mechanics modeling of fatty acid amide hydrolase reactivation distinguishes substrate from irreversible covalent inhibitors. Journal of Medicinal Chemistry. 56: 2500-12. PMID 23425199 DOI: 10.1021/Jm301867X |
0.323 |
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| 2013 |
Realini N, Solorzano C, Pagliuca C, Pizzirani D, Armirotti A, Luciani R, Costi MP, Bandiera T, Piomelli D. Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity. Scientific Reports. 3: 1035. PMID 23301156 DOI: 10.1038/Srep01035 |
0.634 |
|
| 2013 |
Bertolacci L, Romeo E, Veronesi M, Magotti P, Albani C, Dionisi M, Lambruschini C, Scarpelli R, Cavalli A, De Vivo M, Piomelli D, Garau G. A binding site for nonsteroidal anti-inflammatory drugs in fatty acid amide hydrolase. Journal of the American Chemical Society. 135: 22-5. PMID 23240907 DOI: 10.1021/ja308733u |
0.33 |
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| 2013 |
Sasso O, Moreno-Sanz G, Martucci C, Realini N, Dionisi M, Mengatto L, Duranti A, Tarozzo G, Tarzia G, Mor M, Bertorelli R, Reggiani A, Piomelli D. Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models. Pain. 154: 350-60. PMID 23218523 DOI: 10.1016/J.Pain.2012.10.018 |
0.412 |
|
| 2013 |
Greco R, Mangione A, De Icco R, Bandiera T, Sandrini G, Nappi G, Piomelli D, Tassorelli C. Effects of URB937 on an animal model of migraine pain The Journal of Headache and Pain. 14. DOI: 10.1186/1129-2377-14-S1-P68 |
0.316 |
|
| 2012 |
Armirotti A, Romeo E, Ponzano S, Mengatto L, Dionisi M, Karacsonyi C, Bertozzi F, Garau G, Tarozzo G, Reggiani A, Bandiera T, Tarzia G, Mor M, Piomelli D. β-Lactones Inhibit N-acylethanolamine Acid Amidase by S-Acylation of the Catalytic N-Terminal Cysteine. Acs Medicinal Chemistry Letters. 3: 422-6. PMID 24900487 DOI: 10.1021/Ml300056Y |
0.308 |
|
| 2012 |
Favia AD, Habrant D, Scarpelli R, Migliore M, Albani C, Bertozzi SM, Dionisi M, Tarozzo G, Piomelli D, Cavalli A, De Vivo M. Identification and characterization of carprofen as a multitarget fatty acid amide hydrolase/cyclooxygenase inhibitor. Journal of Medicinal Chemistry. 55: 8807-26. PMID 23043222 DOI: 10.1021/jm3011146 |
0.313 |
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| 2012 |
Simoni E, Daniele S, Bottegoni G, Pizzirani D, Trincavelli ML, Goldoni L, Tarozzo G, Reggiani A, Martini C, Piomelli D, Melchiorre C, Rosini M, Cavalli A. Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer's disease. Journal of Medicinal Chemistry. 55: 9708-21. PMID 23033965 DOI: 10.1021/Jm3009458 |
0.303 |
|
| 2012 |
Jung KM, Sepers M, Henstridge CM, Lassalle O, Neuhofer D, Martin H, Ginger M, Frick A, DiPatrizio NV, Mackie K, Katona I, Piomelli D, Manzoni OJ. Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. Nature Communications. 3: 1080. PMID 23011134 DOI: 10.1038/Ncomms2045 |
0.705 |
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| 2012 |
Khasabova IA, Xiong Y, Coicou LG, Piomelli D, Seybold V. Peroxisome proliferator-activated receptor α mediates acute effects of palmitoylethanolamide on sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 12735-43. PMID 22972997 DOI: 10.1523/Jneurosci.0130-12.2012 |
0.332 |
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| 2012 |
Leweke FM, Piomelli D, Pahlisch F, Muhl D, Gerth CW, Hoyer C, Klosterkötter J, Hellmich M, Koethe D. Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. Translational Psychiatry. 2: e94. PMID 22832859 DOI: 10.1038/Tp.2012.15 |
0.546 |
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| 2012 |
Carloni S, Alonso-Alconada D, Girelli S, Duranti A, Tontini A, Piomelli D, Hilario E, Alvarez A, Balduini W. Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats. Pediatric Research. 72: 400-6. PMID 22821058 DOI: 10.1038/pr.2012.91 |
0.31 |
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| 2012 |
Gregg LC, Jung KM, Spradley JM, Nyilas R, Suplita RL, Zimmer A, Watanabe M, Mackie K, Katona I, Piomelli D, Hohmann AG. Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9457-68. PMID 22787031 DOI: 10.1523/Jneurosci.0013-12.2012 |
0.563 |
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| 2012 |
Moreno-Sanz G, Sasso O, Guijarro A, Oluyemi O, Bertorelli R, Reggiani A, Piomelli D. Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier. British Journal of Pharmacology. 167: 1620-8. PMID 22774772 DOI: 10.1111/j.1476-5381.2012.02098.x |
0.317 |
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| 2012 |
Vaidyanathan V, Bastarrachea RA, Higgins PB, Voruganti VS, Kamath S, DiPatrizio NV, Piomelli D, Comuzzie AG, Parks EJ. Selective cannabinoid-1 receptor blockade benefits fatty acid and triglyceride metabolism significantly in weight-stable nonhuman primates. American Journal of Physiology. Endocrinology and Metabolism. 303: E624-34. PMID 22761159 DOI: 10.1152/Ajpendo.00072.2012 |
0.666 |
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| 2012 |
DiPatrizio NV, Piomelli D. The thrifty lipids: endocannabinoids and the neural control of energy conservation. Trends in Neurosciences. 35: 403-11. PMID 22622030 DOI: 10.1016/j.tins.2012.04.006 |
0.643 |
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| 2012 |
Duranti A, Tontini A, Antonietti F, Vacondio F, Fioni A, Silva C, Lodola A, Rivara S, Solorzano C, Piomelli D, Tarzia G, Mor M. N-(2-oxo-3-oxetanyl)carbamic acid esters as N-acylethanolamine acid amidase inhibitors: synthesis and structure-activity and structure-property relationships. Journal of Medicinal Chemistry. 55: 4824-36. PMID 22515328 DOI: 10.1021/Jm300349J |
0.638 |
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| 2012 |
Sasso O, Bertorelli R, Bandiera T, Scarpelli R, Colombano G, Armirotti A, Moreno-Sanz G, Reggiani A, Piomelli D. Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 65: 553-63. PMID 22420940 DOI: 10.1016/j.phrs.2012.02.012 |
0.375 |
|
| 2012 |
Jung KM, Clapper JR, Fu J, D'Agostino G, Guijarro A, Thongkham D, Avanesian A, Astarita G, DiPatrizio NV, Frontini A, Cinti S, Diano S, Piomelli D. 2-arachidonoylglycerol signaling in forebrain regulates systemic energy metabolism. Cell Metabolism. 15: 299-310. PMID 22405068 DOI: 10.1016/J.Cmet.2012.01.021 |
0.794 |
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| 2012 |
Newberry EP, Kennedy SM, Xie Y, Luo J, Crooke RM, Graham MJ, Fu J, Piomelli D, Davidson NO. Decreased body weight and hepatic steatosis with altered fatty acid ethanolamide metabolism in aged L-Fabp -/- mice. Journal of Lipid Research. 53: 744-54. PMID 22327204 DOI: 10.1194/Jlr.M020966 |
0.334 |
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| 2012 |
Snigdha S, Astarita G, Piomelli D, Cotman CW. Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain. Neuroscience. 202: 326-33. PMID 22183056 DOI: 10.1016/j.neuroscience.2011.12.002 |
0.344 |
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| 2012 |
Fu J, Bottegoni G, Sasso O, Bertorelli R, Rocchia W, Masetti M, Guijarro A, Lodola A, Armirotti A, Garau G, Bandiera T, Reggiani A, Mor M, Cavalli A, Piomelli D. A catalytically silent FAAH-1 variant drives anandamide transport in neurons. Nature Neuroscience. 15: 64-9. PMID 22101642 DOI: 10.1038/nn.2986 |
0.351 |
|
| 2012 |
Leweke FM, Koethe D, Pahlisch F, Hellmich M, Rohleder C, Meyer-Lindenberg A, Piomelli D. A TWIN STUDY ON ABNORMALITIES OF ENDOCANNABINOID FUNCTIONING IN SCHIZOPHRENIA AND BIPOLAR DISORDER Schizophrenia Research. 136: S26-S27. DOI: 10.1016/S0920-9964(12)70093-2 |
0.495 |
|
| 2011 |
Cippitelli A, Astarita G, Duranti A, Caprioli G, Ubaldi M, Stopponi S, Kallupi M, Sagratini G, Rodrìguez de Fonseca F, Piomelli D, Ciccocioppo R. Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. Plos One. 6: e28142. PMID 22140525 DOI: 10.1371/Journal.Pone.0028142 |
0.525 |
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| 2011 |
Astarita G, Jung KM, Vasilevko V, Dipatrizio NV, Martin SK, Cribbs DH, Head E, Cotman CW, Piomelli D. Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease. Plos One. 6: e24777. PMID 22046234 DOI: 10.1371/journal.pone.0024777 |
0.643 |
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| 2011 |
Palermo G, Branduardi D, Masetti M, Lodola A, Mor M, Piomelli D, Cavalli A, De Vivo M. Covalent inhibitors of fatty acid amide hydrolase: a rationale for the activity of piperidine and piperazine aryl ureas. Journal of Medicinal Chemistry. 54: 6612-23. PMID 21830831 DOI: 10.1021/Jm2004283 |
0.342 |
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| 2011 |
Vacondio F, Silva C, Lodola A, Carmi C, Rivara S, Duranti A, Tontini A, Sanchini S, Clapper JR, Piomelli D, Tarzia G, Mor M. Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: steric effects of N-alkyl chain on rat plasma and liver stability. European Journal of Medicinal Chemistry. 46: 4466-73. PMID 21820769 DOI: 10.1016/J.Ejmech.2011.07.021 |
0.751 |
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| 2011 |
Moreno-Sanz G, Barrera B, Guijarro A, d'Elia I, Otero JA, Alvarez AI, Bandiera T, Merino G, Piomelli D. The ABC membrane transporter ABCG2 prevents access of FAAH inhibitor URB937 to the central nervous system. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 64: 359-63. PMID 21767647 DOI: 10.1016/j.phrs.2011.07.001 |
0.355 |
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| 2011 |
DiPatrizio NV, Astarita G, Schwartz G, Li X, Piomelli D. Endocannabinoid signal in the gut controls dietary fat intake. Proceedings of the National Academy of Sciences of the United States of America. 108: 12904-8. PMID 21730161 DOI: 10.1073/pnas.1104675108 |
0.662 |
|
| 2011 |
Astarita G, Piomelli D. Towards a whole-body systems [multi-organ] lipidomics in Alzheimer's disease. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 85: 197-203. PMID 21543199 DOI: 10.1016/j.plefa.2011.04.021 |
0.306 |
|
| 2011 |
Fu J, Dipatrizio NV, Guijarro A, Schwartz GJ, Li X, Gaetani S, Astarita G, Piomelli D. Sympathetic activity controls fat-induced oleoylethanolamide signaling in small intestine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 5730-6. PMID 21490214 DOI: 10.1523/JNEUROSCI.5668-10.2011 |
0.668 |
|
| 2011 |
Di Sabatino A, Battista N, Biancheri P, Rapino C, Rovedatti L, Astarita G, Vanoli A, Dainese E, Guerci M, Piomelli D, Pender SL, MacDonald TT, Maccarrone M, Corazza GR. The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease. Mucosal Immunology. 4: 574-83. PMID 21471961 DOI: 10.1038/mi.2011.18 |
0.372 |
|
| 2011 |
Zhu C, Solorzano C, Sahar S, Realini N, Fung E, Sassone-Corsi P, Piomelli D. Proinflammatory stimuli control N-acylphosphatidylethanolamine-specific phospholipase D expression in macrophages. Molecular Pharmacology. 79: 786-92. PMID 21233218 DOI: 10.1124/Mol.110.070201 |
0.691 |
|
| 2011 |
Guindon J, Guijarro A, Piomelli D, Hohmann AG. Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. British Journal of Pharmacology. 163: 1464-78. PMID 21198549 DOI: 10.1111/j.1476-5381.2010.01192.x |
0.383 |
|
| 2011 |
Wang H, Astarita G, Taussig MD, Bharadwaj KG, DiPatrizio NV, Nave KA, Piomelli D, Goldberg IJ, Eckel RH. Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity. Cell Metabolism. 13: 105-13. PMID 21195353 DOI: 10.1016/J.Cmet.2010.12.006 |
0.678 |
|
| 2011 |
Cassano T, Gaetani S, Macheda T, Laconca L, Romano A, Morgese MG, Cimmino CS, Chiarotti F, Bambico FR, Gobbi G, Cuomo V, Piomelli D. Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice. Psychopharmacology. 214: 465-76. PMID 21042794 DOI: 10.1007/S00213-010-2051-0 |
0.318 |
|
| 2011 |
Ludányi A, Hu SS, Yamazaki M, Tanimura A, Piomelli D, Watanabe M, Kano M, Sakimura K, Maglóczky Z, Mackie K, Freund TF, Katona I. Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus. Neuroscience. 174: 50-63. PMID 21035522 DOI: 10.1016/J.Neuroscience.2010.10.062 |
0.516 |
|
| 2011 |
Mascia P, Pistis M, Justinova Z, Panlilio LV, Luchicchi A, Lecca S, Scherma M, Fratta W, Fadda P, Barnes C, Redhi GH, Yasar S, Le Foll B, Tanda G, Piomelli D, et al. Blockade of nicotine reward and reinstatement by activation of alpha-type peroxisome proliferator-activated receptors. Biological Psychiatry. 69: 633-41. PMID 20801430 DOI: 10.1016/J.Biopsych.2010.07.009 |
0.333 |
|
| 2011 |
Ludányi A, Hu SSJ, Yamazaki M, Tanimura A, Piomelli D, Watanabe M, Kano M, Sakimura K, Maglóczky Z, Mackie K, Freund TF, Katona I. Corrigendum to "Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus". [Neuroscience 174 (2011) 50-63]. Neuroscience. 186: 220. DOI: 10.1016/J.Neuroscience.2011.04.072 |
0.452 |
|
| 2011 |
Dipatrizio N, Piomelli D. Intestinal endocannabinoid metabolism mediates the cephalic control of dietary fat intake Appetite. 57: S13. DOI: 10.1016/j.appet.2011.05.159 |
0.623 |
|
| 2011 |
Cippitelli A, Cannella N, Braconi S, Duranti A, Tontini A, Bilbao A, DeFonseca FR, Piomelli D, Ciccocioppo R. Erratum to: Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat Psychopharmacology. 216: 151-151. DOI: 10.1007/S00213-011-2333-1 |
0.494 |
|
| 2010 |
Grimaldi B, Bellet MM, Katada S, Astarita G, Hirayama J, Amin RH, Granneman JG, Piomelli D, Leff T, Sassone-Corsi P. PER2 controls lipid metabolism by direct regulation of PPARγ. Cell Metabolism. 12: 509-20. PMID 21035761 DOI: 10.1016/J.Cmet.2010.10.005 |
0.325 |
|
| 2010 |
Clapper JR, Moreno-Sanz G, Russo R, Guijarro A, Vacondio F, Duranti A, Tontini A, Sanchini S, Sciolino NR, Spradley JM, Hohmann AG, Calignano A, Mor M, Tarzia G, Piomelli D. Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism. Nature Neuroscience. 13: 1265-70. PMID 20852626 DOI: 10.1038/Nn.2632 |
0.774 |
|
| 2010 |
Solorzano C, Antonietti F, Duranti A, Tontini A, Rivara S, Lodola A, Vacondio F, Tarzia G, Piomelli D, Mor M. Synthesis and structure-activity relationships of N-(2-oxo-3-oxetanyl)amides as N-acylethanolamine-hydrolyzing acid amidase inhibitors. Journal of Medicinal Chemistry. 53: 5770-81. PMID 20604568 DOI: 10.1021/Jm100582W |
0.658 |
|
| 2010 |
Gaetani S, Fu J, Cassano T, Dipasquale P, Romano A, Righetti L, Cianci S, Laconca L, Giannini E, Scaccianoce S, Mairesse J, Cuomo V, Piomelli D. The fat-induced satiety factor oleoylethanolamide suppresses feeding through central release of oxytocin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8096-101. PMID 20554860 DOI: 10.1523/JNEUROSCI.0036-10.2010 |
0.376 |
|
| 2010 |
Alkaitis MS, Solorzano C, Landry RP, Piomelli D, DeLeo JA, Romero-Sandoval EA. Evidence for a role of endocannabinoids, astrocytes and p38 phosphorylation in the resolution of postoperative pain. Plos One. 5: e10891. PMID 20531936 DOI: 10.1371/Journal.Pone.0010891 |
0.655 |
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| 2010 |
Eisenstein SA, Clapper JR, Holmes PV, Piomelli D, Hohmann AG. A role for 2-arachidonoylglycerol and endocannabinoid signaling in the locomotor response to novelty induced by olfactory bulbectomy. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 61: 419-29. PMID 20044005 DOI: 10.1016/J.Phrs.2009.12.013 |
0.762 |
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| 2010 |
Touriño C, Oveisi F, Lockney J, Piomelli D, Maldonado R. FAAH deficiency promotes energy storage and enhances the motivation for food. International Journal of Obesity (2005). 34: 557-68. PMID 20029375 DOI: 10.1038/ijo.2009.262 |
0.317 |
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| 2010 |
Dipatrizio N, Astarita G, Shibuya A, Li X, Schwartz G, Piomelli D. Fat intake stimulates endocannabinoid mobilization in the small intestine through a cephalic mechanism Appetite. 54: 644. DOI: 10.1016/j.appet.2010.04.061 |
0.617 |
|
| 2009 |
Solorzano C, Zhu C, Battista N, Astarita G, Lodola A, Rivara S, Mor M, Russo R, Maccarrone M, Antonietti F, Duranti A, Tontini A, Cuzzocrea S, Tarzia G, Piomelli D. Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation. Proceedings of the National Academy of Sciences of the United States of America. 106: 20966-71. PMID 19926854 DOI: 10.1073/Pnas.0907417106 |
0.717 |
|
| 2009 |
King AR, Dotsey EY, Lodola A, Jung KM, Ghomian A, Qiu Y, Fu J, Mor M, Piomelli D. Discovery of potent and reversible monoacylglycerol lipase inhibitors. Chemistry & Biology. 16: 1045-52. PMID 19875078 DOI: 10.1016/J.Chembiol.2009.09.012 |
0.785 |
|
| 2009 |
Clapper JR, Vacondio F, King AR, Duranti A, Tontini A, Silva C, Sanchini S, Tarzia G, Mor M, Piomelli D. A second generation of carbamate-based fatty acid amide hydrolase inhibitors with improved activity in vivo. Chemmedchem. 4: 1505-13. PMID 19637155 DOI: 10.1002/Cmdc.200900210 |
0.808 |
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| 2009 |
Gaetani S, Dipasquale P, Romano A, Righetti L, Cassano T, Piomelli D, Cuomo V. The endocannabinoid system as a target for novel anxiolytic and antidepressant drugs. International Review of Neurobiology. 85: 57-72. PMID 19607961 DOI: 10.1016/S0074-7742(09)85005-8 |
0.428 |
|
| 2009 |
Astarita G, Geaga J, Ahmed F, Piomelli D. Targeted lipidomics as a tool to investigate endocannabinoid function. International Review of Neurobiology. 85: 35-55. PMID 19607960 DOI: 10.1016/S0074-7742(09)85004-6 |
0.328 |
|
| 2009 |
Vacondio F, Silva C, Lodola A, Fioni A, Rivara S, Duranti A, Tontini A, Sanchini S, Clapper JR, Piomelli D, Mor M, Tarzia G. Structure-property relationships of a class of carbamate-based fatty acid amide hydrolase (FAAH) inhibitors: chemical and biological stability. Chemmedchem. 4: 1495-504. PMID 19554599 DOI: 10.1002/Cmdc.200900120 |
0.755 |
|
| 2009 |
King AR, Lodola A, Carmi C, Fu J, Mor M, Piomelli D. A critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone-based enzyme inhibitors. British Journal of Pharmacology. 157: 974-83. PMID 19486005 DOI: 10.1111/j.1476-5381.2009.00276.x |
0.546 |
|
| 2009 |
Campolongo P, Roozendaal B, Trezza V, Cuomo V, Astarita G, Fu J, McGaugh JL, Piomelli D. Fat-induced satiety factor oleoylethanolamide enhances memory consolidation. Proceedings of the National Academy of Sciences of the United States of America. 106: 8027-31. PMID 19416833 DOI: 10.1073/Pnas.0903038106 |
0.314 |
|
| 2009 |
D'Agostino G, La Rana G, Russo R, Sasso O, Iacono A, Esposito E, Mattace Raso G, Cuzzocrea S, Loverme J, Piomelli D, Meli R, Calignano A. Central administration of palmitoylethanolamide reduces hyperalgesia in mice via inhibition of NF-kappaB nuclear signalling in dorsal root ganglia. European Journal of Pharmacology. 613: 54-9. PMID 19386271 DOI: 10.1016/J.Ejphar.2009.04.022 |
0.79 |
|
| 2009 |
Mangieri RA, Hong KI, Piomelli D, Sinha R. An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. Psychopharmacology. 205: 63-72. PMID 19343330 DOI: 10.1007/s00213-009-1518-3 |
0.678 |
|
| 2009 |
Koethe D, Giuffrida A, Schreiber D, Hellmich M, Schultze-Lutter F, Ruhrmann S, Klosterkötter J, Piomelli D, Leweke FM. Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. The British Journal of Psychiatry : the Journal of Mental Science. 194: 371-2. PMID 19336792 DOI: 10.1192/Bjp.Bp.108.053843 |
0.64 |
|
| 2009 |
Parker LA, Limebeer CL, Rock EM, Litt DL, Kwiatkowska M, Piomelli D. The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew). Physiology & Behavior. 97: 121-4. PMID 19239915 DOI: 10.1016/J.Physbeh.2009.02.014 |
0.302 |
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| 2009 |
Astarita G, Piomelli D. Lipidomic analysis of endocannabinoid metabolism in biological samples. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 2755-67. PMID 19171504 DOI: 10.1016/j.jchromb.2009.01.008 |
0.323 |
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| 2009 |
Fehrenbacher JC, Loverme J, Clarke W, Hargreaves KM, Piomelli D, Taylor BK. Rapid pain modulation with nuclear receptor ligands. Brain Research Reviews. 60: 114-24. PMID 19162071 DOI: 10.1016/J.Brainresrev.2008.12.019 |
0.798 |
|
| 2009 |
Cluny NL, Keenan CM, Lutz B, Piomelli D, Sharkey KA. The identification of peroxisome proliferator-activated receptor alpha-independent effects of oleoylethanolamide on intestinal transit in mice. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 21: 420-9. PMID 19140957 DOI: 10.1016/S0016-5085(08)61141-5 |
0.365 |
|
| 2009 |
Koethe D, Schreiber D, Giuffrida A, Mauss C, Faulhaber J, Heydenreich B, Hellmich M, Graf R, Klosterkötter J, Piomelli D, Leweke FM. Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid. Journal of Neural Transmission (Vienna, Austria : 1996). 116: 301-5. PMID 19137236 DOI: 10.1007/S00702-008-0169-6 |
0.64 |
|
| 2009 |
LoVerme J, Duranti A, Tontini A, Spadoni G, Mor M, Rivara S, Stella N, Xu C, Tarzia G, Piomelli D. Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice. Bioorganic & Medicinal Chemistry Letters. 19: 639-43. PMID 19128970 DOI: 10.1016/J.Bmcl.2008.12.059 |
0.791 |
|
| 2009 |
Clapper JR, Mangieri RA, Piomelli D. The endocannabinoid system as a target for the treatment of cannabis dependence. Neuropharmacology. 56: 235-43. PMID 18691603 DOI: 10.1016/J.Neuropharm.2008.07.018 |
0.808 |
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| 2009 |
Leweke F, Giuffrida A, Pahlisch F, Kranaster L, Hoyer C, Jöpen C, Hellmich M, Klosterkötter J, Piomelli D, Koethe D. Functional Sspects of the Endocannabinoid System in Schizophrenia European Psychiatry. 24: 1-1. DOI: 10.1016/S0924-9338(09)70265-2 |
0.315 |
|
| 2009 |
Vacondio F, Silva C, Lodola A, Fioni A, Rivara S, Duranti A, Tontini A, Sanchini S, Clapper JR, Piomelli D, Mor M, Tarzia G, King A. Cover Picture: Structure-Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability / A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo (ChemMedChem 9/2009) Chemmedchem. 4: 1385-1385. DOI: 10.1002/Cmdc.200990041 |
0.789 |
|
| 2008 |
Gaetani S, Kaye WH, Cuomo V, Piomelli D. Role of endocannabinoids and their analogues in obesity and eating disorders. Eating and Weight Disorders : Ewd. 13: e42-8. PMID 19011363 DOI: 10.1007/Bf03327526 |
0.386 |
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| 2008 |
Duncan M, Thomas AD, Cluny NL, Patel A, Patel KD, Lutz B, Piomelli D, Alexander SP, Sharkey KA. Distribution and function of monoacylglycerol lipase in the gastrointestinal tract. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G1255-65. PMID 18948437 DOI: 10.1152/Ajpgi.90500.2008 |
0.32 |
|
| 2008 |
Schwartz GJ, Fu J, Astarita G, Li X, Gaetani S, Campolongo P, Cuomo V, Piomelli D. The lipid messenger OEA links dietary fat intake to satiety. Cell Metabolism. 8: 281-8. PMID 18840358 DOI: 10.1016/j.cmet.2008.08.005 |
0.33 |
|
| 2008 |
Justinova Z, Mangieri RA, Bortolato M, Chefer SI, Mukhin AG, Clapper JR, King AR, Redhi GH, Yasar S, Piomelli D, Goldberg SR. Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates. Biological Psychiatry. 64: 930-7. PMID 18814866 DOI: 10.1016/J.Biopsych.2008.08.008 |
0.793 |
|
| 2008 |
Scherma M, Panlilio LV, Fadda P, Fattore L, Gamaleddin I, Le Foll B, Justinová Z, Mikics E, Haller J, Medalie J, Stroik J, Barnes C, Yasar S, Tanda G, Piomelli D, et al. Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in rats. The Journal of Pharmacology and Experimental Therapeutics. 327: 482-90. PMID 18725543 DOI: 10.1124/Jpet.108.142224 |
0.349 |
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| 2008 |
Moise AM, Eisenstein SA, Astarita G, Piomelli D, Hohmann AG. An endocannabinoid signaling system modulates anxiety-like behavior in male Syrian hamsters. Psychopharmacology. 200: 333-46. PMID 18545985 DOI: 10.1007/S00213-008-1209-5 |
0.379 |
|
| 2008 |
Mor M, Lodola A, Rivara S, Vacondio F, Duranti A, Tontini A, Sanchini S, Piersanti G, Clapper JR, King AR, Tarzia G, Piomelli D. Synthesis and quantitative structure-activity relationship of fatty acid amide hydrolase inhibitors: modulation at the N-portion of biphenyl-3-yl alkylcarbamates. Journal of Medicinal Chemistry. 51: 3487-98. PMID 18507372 DOI: 10.1021/JM801482Q |
0.791 |
|
| 2008 |
Koethe D, Bortolato M, Piomelli D, Leweke FM. Improvement of general symptoms in a chronic psychotic patient treated with finasteride: case report. Pharmacopsychiatry. 41: 115-6. PMID 18484553 DOI: 10.1055/S-2008-1058110 |
0.5 |
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| 2008 |
Cippitelli A, Cannella N, Braconi S, Duranti A, Tontini A, Bilbao A, Defonseca FR, Piomelli D, Ciccocioppo R. Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat. Psychopharmacology. 198: 449-60. PMID 18446329 DOI: 10.1007/S00213-008-1104-0 |
0.512 |
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| 2008 |
Fu J, Kim J, Oveisi F, Astarita G, Piomelli D. Targeted enhancement of oleoylethanolamide production in proximal small intestine induces across-meal satiety in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R45-50. PMID 18434444 DOI: 10.1152/ajpregu.00126.2008 |
0.314 |
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| 2008 |
Solinas M, Goldberg SR, Piomelli D. The endocannabinoid system in brain reward processes. British Journal of Pharmacology. 154: 369-83. PMID 18414385 DOI: 10.1038/Bjp.2008.130 |
0.327 |
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| 2008 |
La Rana G, Russo R, D'Agostino G, Sasso O, Raso GM, Iacono A, Meli R, Piomelli D, Calignano A. AM404, an anandamide transport inhibitor, reduces plasma extravasation in a model of neuropathic pain in rat: role for cannabinoid receptors. Neuropharmacology. 54: 521-9. PMID 18093621 DOI: 10.1016/j.neuropharm.2007.10.021 |
0.329 |
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| 2008 |
Rock EM, Limebeer CL, Mechoulam R, Piomelli D, Parker LA. The effect of cannabidiol and URB597 on conditioned gaping (a model of nausea) elicited by a lithium-paired context in the rat. Psychopharmacology. 196: 389-95. PMID 17992520 DOI: 10.1007/S00213-007-0970-1 |
0.3 |
|
| 2008 |
Astarita G, Ahmed F, Piomelli D. Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain. Journal of Lipid Research. 49: 48-57. PMID 17957091 DOI: 10.1194/jlr.M700354-JLR200 |
0.312 |
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| 2008 |
Scherma M, Medalie J, Fratta W, Vadivel SK, Makriyannis A, Piomelli D, Mikics E, Haller J, Yasar S, Tanda G, Goldberg SR. The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition. Neuropharmacology. 54: 129-40. PMID 17904589 DOI: 10.1016/J.Neuropharm.2007.08.011 |
0.368 |
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| 2008 |
Bortolato M, Piomelli D. Chapter 4.5 The endocannabinoid system and anxiety responses Handbook of Behavioral Neuroscience. 17: 303-324. DOI: 10.1016/S1569-7339(07)00014-8 |
0.317 |
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| 2008 |
Koethe D, Giuffrida A, Schreiber D, Hellmich M, Schultze-Lutter F, Ruhrmann S, Klosterkoetter J, Piomelli D, Leweke F. P.3.f.001 Does anandamide elevation in cerebrospinal fluid protect against transition into frank psychosis? European Neuropsychopharmacology. 18: S474. DOI: 10.1016/S0924-977X(08)70706-5 |
0.449 |
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| 2007 |
King AR, Duranti A, Tontini A, Rivara S, Rosengarth A, Clapper JR, Astarita G, Geaga JA, Luecke H, Mor M, Tarzia G, Piomelli D. URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. Chemistry & Biology. 14: 1357-65. PMID 18096504 DOI: 10.1016/J.Chembiol.2007.10.017 |
0.803 |
|
| 2007 |
Tarzia G, Antonietti F, Duranti A, Tontini A, Mor M, Rivara S, Traldi P, Astarita G, King A, Clapper JR, Piomelli D. Identification of a bioactive impurity in a commercial sample of 6-methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754). Annali Di Chimica. 97: 887-94. PMID 17970304 DOI: 10.1002/Adic.200790073 |
0.775 |
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| 2007 |
Mangieri RA, Piomelli D. Enhancement of endocannabinoid signaling and the pharmacotherapy of depression. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 56: 360-6. PMID 17945507 DOI: 10.1016/j.phrs.2007.09.003 |
0.706 |
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| 2007 |
Cippitelli A, Bilbao A, Gorriti MA, Navarro M, Massi M, Piomelli D, Ciccocioppo R, RodrÃguez de Fonseca F. The anandamide transport inhibitor AM404 reduces ethanol self-administration. The European Journal of Neuroscience. 26: 476-86. PMID 17650118 DOI: 10.1111/J.1460-9568.2007.05665.X |
0.515 |
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| 2007 |
Vila A, Rosengarth A, Piomelli D, Cravatt B, Marnett LJ. Hydrolysis of prostaglandin glycerol esters by the endocannabinoid-hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase. Biochemistry. 46: 9578-85. PMID 17649977 DOI: 10.1021/Bi7005898 |
0.347 |
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| 2007 |
Jung KM, Astarita G, Zhu C, Wallace M, Mackie K, Piomelli D. A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization. Molecular Pharmacology. 72: 612-21. PMID 17584991 DOI: 10.1124/Mol.107.037796 |
0.618 |
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| 2007 |
Leweke FM, Giuffrida A, Koethe D, Schreiber D, Nolden BM, Kranaster L, Neatby MA, Schneider M, Gerth CW, Hellmich M, Klosterkötter J, Piomelli D. Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use. Schizophrenia Research. 94: 29-36. PMID 17566707 DOI: 10.1016/J.Schres.2007.04.025 |
0.638 |
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| 2007 |
D'Agostino G, La Rana G, Russo R, Sasso O, Iacono A, Esposito E, Raso GM, Cuzzocrea S, Lo Verme J, Piomelli D, Meli R, Calignano A. Acute intracerebroventricular administration of palmitoylethanolamide, an endogenous peroxisome proliferator-activated receptor-alpha agonist, modulates carrageenan-induced paw edema in mice. The Journal of Pharmacology and Experimental Therapeutics. 322: 1137-43. PMID 17565008 DOI: 10.1124/jpet.107.123265 |
0.331 |
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| 2007 |
Guindon J, LoVerme J, Piomelli D, Beaulieu P. The antinociceptive effects of local injections of propofol in rats are mediated in part by cannabinoid CB1 and CB2 receptors. Anesthesia and Analgesia. 104: 1563-9, table of con. PMID 17513659 DOI: 10.1213/01.Ane.0000263278.05423.A3 |
0.806 |
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| 2007 |
Bortolato M, Mangieri RA, Fu J, Kim JH, Arguello O, Duranti A, Tontini A, Mor M, Tarzia G, Piomelli D. Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress. Biological Psychiatry. 62: 1103-10. PMID 17511970 DOI: 10.1016/J.Biopsych.2006.12.001 |
0.737 |
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| 2007 |
Russo R, LoVerme J, La Rana G, D'Agostino G, Sasso O, Calignano A, Piomelli D. Synergistic antinociception by the cannabinoid receptor agonist anandamide and the PPAR-alpha receptor agonist GW7647. European Journal of Pharmacology. 566: 117-9. PMID 17434479 DOI: 10.1016/J.Ejphar.2007.03.007 |
0.795 |
|
| 2007 |
Russo R, Loverme J, La Rana G, Compton TR, Parrott J, Duranti A, Tontini A, Mor M, Tarzia G, Calignano A, Piomelli D. The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice. The Journal of Pharmacology and Experimental Therapeutics. 322: 236-42. PMID 17412883 DOI: 10.1124/Jpet.107.119941 |
0.814 |
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| 2007 |
Ferrer B, Bermúdez-Silva FJ, Bilbao A, Alvarez-Jaimes L, Sanchez-Vera I, Giuffrida A, Serrano A, Baixeras E, Khaturia S, Navarro M, Parsons LH, Piomelli D, RodrÃguez de Fonseca F. Regulation of brain anandamide by acute administration of ethanol. The Biochemical Journal. 404: 97-104. PMID 17302558 DOI: 10.1042/Bj20061898 |
0.522 |
|
| 2007 |
Solinas M, Tanda G, Justinova Z, Wertheim CE, Yasar S, Piomelli D, Vadivel SK, Makriyannis A, Goldberg SR. The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport. The Journal of Pharmacology and Experimental Therapeutics. 321: 370-80. PMID 17210800 DOI: 10.1124/Jpet.106.114124 |
0.387 |
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| 2007 |
Schreiber D, Harlfinger S, Nolden BM, Gerth CW, Jaehde U, Schömig E, Klosterkötter J, Giuffrida A, Astarita G, Piomelli D, Markus Leweke F. Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry. Analytical Biochemistry. 361: 162-8. PMID 17196922 DOI: 10.1016/J.Ab.2006.11.027 |
0.5 |
|
| 2007 |
Fu J, Astarita G, Gaetani S, Kim J, Cravatt BF, Mackie K, Piomelli D. Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine. The Journal of Biological Chemistry. 282: 1518-28. PMID 17121838 DOI: 10.1074/Jbc.M607809200 |
0.549 |
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| 2007 |
Cross-Mellor SK, Ossenkopp KP, Piomelli D, Parker LA. Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. Psychopharmacology. 190: 135-43. PMID 17111174 DOI: 10.1007/S00213-006-0589-7 |
0.337 |
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| 2007 |
Justinova Z, Bortolato M, Mangieri R, Mukhin AG, Chefer SI, Piomelli D, Goldberg SR. Lack of abuse liability of the FAAH inhibitor URB597 in squirrel monkeys The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A409-C |
0.69 |
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| 2007 |
Makara JK, Mor M, Fegley D, Szabó SI, Kathuria S, Astarita G, Duranti A, Tontini A, Tarzia G, Rivara S, Freund TF, Piomelli D. Erratum: Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus Nature Neuroscience. 10: 134-134. DOI: 10.1038/Nn0107-134A |
0.767 |
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| 2006 |
Guindon J, LoVerme J, De Léan A, Piomelli D, Beaulieu P. Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides? European Journal of Pharmacology. 550: 68-77. PMID 17027744 DOI: 10.1016/J.Ejphar.2006.08.045 |
0.802 |
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| 2006 |
LoVerme J, Russo R, La Rana G, Fu J, Farthing J, Mattace-Raso G, Meli R, Hohmann A, Calignano A, Piomelli D. Rapid broad-spectrum analgesia through activation of peroxisome proliferator-activated receptor-alpha. The Journal of Pharmacology and Experimental Therapeutics. 319: 1051-61. PMID 16997973 DOI: 10.1124/Jpet.106.111385 |
0.794 |
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| 2006 |
Clapper JR, Duranti A, Tontini A, Mor M, Tarzia G, Piomelli D. The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 54: 341-4. PMID 16935521 DOI: 10.1016/J.Phrs.2006.06.008 |
0.772 |
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| 2006 |
Pintor A, Tebano MT, Martire A, Grieco R, Galluzzo M, Scattoni ML, Pèzzola A, Coccurello R, Felici F, Cuomo V, Piomelli D, Calamandrei G, Popoli P. The cannabinoid receptor agonist WIN 55,212-2 attenuates the effects induced by quinolinic acid in the rat striatum. Neuropharmacology. 51: 1004-12. PMID 16895732 DOI: 10.1016/j.neuropharm.2006.06.013 |
0.366 |
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| 2006 |
Tarzia G, Duranti A, Gatti G, Piersanti G, Tontini A, Rivara S, Lodola A, Plazzi PV, Mor M, Kathuria S, Piomelli D. Synthesis and structure-activity relationships of FAAH inhibitors: cyclohexylcarbamic acid biphenyl esters with chemical modulation at the proximal phenyl ring. Chemmedchem. 1: 130-9. PMID 16892344 DOI: 10.1002/Cmdc.200500017 |
0.321 |
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| 2006 |
Piomelli D, Tarzia G, Duranti A, Tontini A, Mor M, Compton TR, Dasse O, Monaghan EP, Parrott JA, Putman D. Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597). Cns Drug Reviews. 12: 21-38. PMID 16834756 DOI: 10.1111/J.1527-3458.2006.00021.X |
0.403 |
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| 2006 |
LoVerme J, Guzmán M, Gaetani S, Piomelli D. Cold exposure stimulates synthesis of the bioactive lipid oleoylethanolamide in rat adipose tissue. The Journal of Biological Chemistry. 281: 22815-8. PMID 16785227 DOI: 10.1074/Jbc.M604751200 |
0.802 |
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| 2006 |
Katona I, Urbán GM, Wallace M, Ledent C, Jung KM, Piomelli D, Mackie K, Freund TF. Molecular composition of the endocannabinoid system at glutamatergic synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5628-37. PMID 16723519 DOI: 10.1523/Jneurosci.0309-06.2006 |
0.502 |
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| 2006 |
Astarita G, Di Giacomo B, Gaetani S, Oveisi F, Compton TR, Rivara S, Tarzia G, Mor M, Piomelli D. Pharmacological characterization of hydrolysis-resistant analogs of oleoylethanolamide with potent anorexiant properties. The Journal of Pharmacology and Experimental Therapeutics. 318: 563-70. PMID 16702440 DOI: 10.1124/Jpet.106.105221 |
0.353 |
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| 2006 |
Bortolato M, Campolongo P, Mangieri RA, Scattoni ML, Frau R, Trezza V, La Rana G, Russo R, Calignano A, Gessa GL, Cuomo V, Piomelli D. Anxiolytic-like properties of the anandamide transport inhibitor AM404. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2652-9. PMID 16541083 DOI: 10.1038/Sj.Npp.1301061 |
0.734 |
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| 2006 |
La Rana G, Russo R, Campolongo P, Bortolato M, Mangieri RA, Cuomo V, Iacono A, Raso GM, Meli R, Piomelli D, Calignano A. Modulation of neuropathic and inflammatory pain by the endocannabinoid transport inhibitor AM404 [N-(4-hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide]. The Journal of Pharmacology and Experimental Therapeutics. 317: 1365-71. PMID 16510698 DOI: 10.1124/Jpet.105.100792 |
0.726 |
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| 2006 |
Connell K, Bolton N, Olsen D, Piomelli D, Hohmann AG. Role of the basolateral nucleus of the amygdala in endocannabinoid-mediated stress-induced analgesia. Neuroscience Letters. 397: 180-4. PMID 16378681 DOI: 10.1016/j.neulet.2005.12.008 |
0.363 |
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| 2006 |
Astarita G, Rourke BC, Andersen JB, Fu J, Kim JH, Bennett AF, Hicks JW, Piomelli D. Postprandial increase of oleoylethanolamide mobilization in small intestine of the Burmese python (Python molurus). American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 290: R1407-12. PMID 16373434 DOI: 10.1152/Ajpregu.00664.2005 |
0.359 |
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| 2006 |
Suplita RL, Gutierrez T, Fegley D, Piomelli D, Hohmann AG. Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia. Neuropharmacology. 50: 372-9. PMID 16316669 DOI: 10.1016/J.Neuropharm.2005.10.007 |
0.789 |
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| 2006 |
Gobbi G, Bambico FR, Mangieri R, Bortolato M, Campolongo P, Solinas M, Cassano T, Morgese MG, Debonnel G, Duranti A, Tontini A, Tarzia G, Mor M, Trezza V, Goldberg SR, ... ... Piomelli D, et al. Erratum: Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis (Proceedings of the National Academy of Sciences of the United States of America (December 20, 2005) 102, 51 (18620-18625) DOI: 10.1073/pnas.0509591102) Proceedings of the National Academy of Sciences of the United States of America. 103: 2465. DOI: 10.1073/Pnas.0511247103 |
0.683 |
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| 2005 |
Gobbi G, Bambico FR, Mangieri R, Bortolato M, Campolongo P, Solinas M, Cassano T, Morgese MG, Debonnel G, Duranti A, Tontini A, Tarzia G, Mor M, Trezza V, Goldberg SR, ... ... Piomelli D, et al. Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 102: 18620-5. PMID 16352709 DOI: 10.1073/Pnas.0509591102 |
0.754 |
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| 2005 |
Van Sickle MD, Duncan M, Kingsley PJ, Mouihate A, Urbani P, Mackie K, Stella N, Makriyannis A, Piomelli D, Davison JS, Marnett LJ, Di Marzo V, Pittman QJ, Patel KD, Sharkey KA. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science (New York, N.Y.). 310: 329-32. PMID 16224028 DOI: 10.1126/Science.1115740 |
0.659 |
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| 2005 |
Lodola A, Mor M, Hermann JC, Tarzia G, Piomelli D, Mulholland AJ. QM/MM modelling of oleamide hydrolysis in fatty acid amide hydrolase (FAAH) reveals a new mechanism of nucleophile activation. Chemical Communications (Cambridge, England). 4399-401. PMID 16136230 DOI: 10.1039/B503887A |
0.331 |
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| 2005 |
Makara JK, Mor M, Fegley D, Szabó SI, Kathuria S, Astarita G, Duranti A, Tontini A, Tarzia G, Rivara S, Freund TF, Piomelli D. Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus. Nature Neuroscience. 8: 1139-41. PMID 16116451 DOI: 10.1038/Nn1521 |
0.788 |
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| 2005 |
Piomelli D. The challenge of brain lipidomics. Prostaglandins & Other Lipid Mediators. 77: 23-34. PMID 16099388 DOI: 10.1016/j.prostaglandins.2004.09.006 |
0.319 |
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| 2005 |
Jung KM, Mangieri R, Stapleton C, Kim J, Fegley D, Wallace M, Mackie K, Piomelli D. Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors. Molecular Pharmacology. 68: 1196-202. PMID 16051747 DOI: 10.1124/Mol.105.013961 |
0.793 |
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| 2005 |
Solbrig MV, Adrian R, Baratta J, Piomelli D, Giuffrida A. A role for endocannabinoids in viral-induced dyskinetic and convulsive phenomena. Experimental Neurology. 194: 355-62. PMID 16022863 DOI: 10.1016/J.Expneurol.2005.02.017 |
0.502 |
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| 2005 |
Hohmann AG, Suplita RL, Bolton NM, Neely MH, Fegley D, Mangieri R, Krey JF, Walker JM, Holmes PV, Crystal JD, Duranti A, Tontini A, Mor M, Tarzia G, Piomelli D. An endocannabinoid mechanism for stress-induced analgesia. Nature. 435: 1108-12. PMID 15973410 DOI: 10.1038/Nature03658 |
0.79 |
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| 2005 |
LoVerme J, La Rana G, Russo R, Calignano A, Piomelli D. The search for the palmitoylethanolamide receptor. Life Sciences. 77: 1685-98. PMID 15963531 DOI: 10.1016/J.Lfs.2005.05.012 |
0.8 |
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| 2005 |
Fu J, Oveisi F, Gaetani S, Lin E, Piomelli D. Oleoylethanolamide, an endogenous PPAR-alpha agonist, lowers body weight and hyperlipidemia in obese rats. Neuropharmacology. 48: 1147-53. PMID 15910890 DOI: 10.1016/j.neuropharm.2005.02.013 |
0.35 |
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| 2005 |
Makriyannis A, Mechoulam R, Piomelli D. Therapeutic opportunities through modulation of the endocannabinoid system. Neuropharmacology. 48: 1068-71. PMID 15885714 DOI: 10.1016/j.neuropharm.2005.03.012 |
0.337 |
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| 2005 |
Lo Verme J, Gaetani S, Fu J, Oveisi F, Burton K, Piomelli D. Regulation of food intake by oleoylethanolamide. Cellular and Molecular Life Sciences : Cmls. 62: 708-16. PMID 15770421 DOI: 10.1007/s00018-004-4494-0 |
0.331 |
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| 2005 |
Fegley D, Gaetani S, Duranti A, Tontini A, Mor M, Tarzia G, Piomelli D. Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation. The Journal of Pharmacology and Experimental Therapeutics. 313: 352-8. PMID 15579492 DOI: 10.1124/Jpet.104.078980 |
0.811 |
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| 2005 |
Lo Verme J, Fu J, Astarita G, La Rana G, Russo R, Calignano A, Piomelli D. The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide. Molecular Pharmacology. 67: 15-9. PMID 15465922 DOI: 10.1124/mol.104.006353 |
0.314 |
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| 2005 |
Leweke F, Giuffrida A, Koethe D, Nolden B, Gerth C, Schreiber D, Gross S, Juelicher A, Klosterkötter J, Piomelli D. The role of the endogenous cannabinoid system in schizophrenia Pharmacopsychiatry. 38. DOI: 10.1055/s-2005-918765 |
0.452 |
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| 2004 |
Piomelli D. The endogenous cannabinoid system and the treatment of marijuana dependence. Neuropharmacology. 47: 359-67. PMID 15464150 DOI: 10.1016/j.neuropharm.2004.07.018 |
0.372 |
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| 2004 |
Mor M, Rivara S, Lodola A, Plazzi PV, Tarzia G, Duranti A, Tontini A, Piersanti G, Kathuria S, Piomelli D. Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies. Journal of Medicinal Chemistry. 47: 4998-5008. PMID 15456244 DOI: 10.1021/Jm031140X |
0.336 |
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| 2004 |
Giuffrida A, Leweke FM, Gerth CW, Schreiber D, Koethe D, Faulhaber J, Klosterkötter J, Piomelli D. Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 2108-14. PMID 15354183 DOI: 10.1038/Sj.Npp.1300558 |
0.655 |
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| 2004 |
Dinh TP, Kathuria S, Piomelli D. RNA interference suggests a primary role for monoacylglycerol lipase in the degradation of the endocannabinoid 2-arachidonoylglycerol. Molecular Pharmacology. 66: 1260-4. PMID 15272052 DOI: 10.1124/Mol.104.002071 |
0.689 |
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| 2004 |
Gulyas AI, Cravatt BF, Bracey MH, Dinh TP, Piomelli D, Boscia F, Freund TF. Segregation of two endocannabinoid-hydrolyzing enzymes into pre- and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala. The European Journal of Neuroscience. 20: 441-58. PMID 15233753 DOI: 10.1111/J.1460-9568.2004.03428.X |
0.677 |
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| 2004 |
Hájos N, Kathuria S, Dinh T, Piomelli D, Freund TF. Endocannabinoid transport tightly controls 2-arachidonoyl glycerol actions in the hippocampus: effects of low temperature and the transport inhibitor AM404. The European Journal of Neuroscience. 19: 2991-6. PMID 15182306 DOI: 10.1111/J.0953-816X.2004.03433.X |
0.678 |
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| 2004 |
Fegley D, Kathuria S, Mercier R, Li C, Goutopoulos A, Makriyannis A, Piomelli D. Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. Proceedings of the National Academy of Sciences of the United States of America. 101: 8756-61. PMID 15138300 DOI: 10.1073/Pnas.0400997101 |
0.805 |
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| 2004 |
Guzmán M, Lo Verme J, Fu J, Oveisi F, Blázquez C, Piomelli D. Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha). The Journal of Biological Chemistry. 279: 27849-54. PMID 15123613 DOI: 10.1074/jbc.M404087200 |
0.344 |
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| 2004 |
Oveisi F, Gaetani S, Eng KT, Piomelli D. Oleoylethanolamide inhibits food intake in free-feeding rats after oral administration. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 49: 461-6. PMID 14998556 DOI: 10.1016/j.phrs.2003.12.006 |
0.303 |
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| 2004 |
Leweke F, Giuffrida A, Koethe D, Schreiber D, Gerth C, Piomelli D, Klosterkötter J. P.2.143 Does cannabis use affect endogenouscannabinoids in schizophrenia? European Neuropsychopharmacology. 14: S295. DOI: 10.1016/S0924-977X(04)80363-8 |
0.452 |
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| 2003 |
Murillo-Rodriguez E, Blanco-Centurion C, Sanchez C, Piomelli D, Shiromani PJ. Anandamide enhances extracellular levels of adenosine and induces sleep: an in vivo microdialysis study. Sleep. 26: 943-7. PMID 14746372 DOI: 10.1093/Sleep/26.8.943 |
0.699 |
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| 2003 |
Sparling PB, Giuffrida A, Piomelli D, Rosskopf L, Dietrich A. Exercise activates the endocannabinoid system. Neuroreport. 14: 2209-11. PMID 14625449 DOI: 10.1097/00001756-200312020-00015 |
0.457 |
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| 2003 |
Gaetani S, Cuomo V, Piomelli D. Anandamide hydrolysis: a new target for anti-anxiety drugs? Trends in Molecular Medicine. 9: 474-8. PMID 14604824 DOI: 10.1016/J.Molmed.2003.09.005 |
0.385 |
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| 2003 |
Piomelli D. The molecular logic of endocannabinoid signalling. Nature Reviews. Neuroscience. 4: 873-84. PMID 14595399 DOI: 10.1038/nrn1247 |
0.339 |
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| 2003 |
Ferrer B, Asbrock N, Kathuria S, Piomelli D, Giuffrida A. Effects of levodopa on endocannabinoid levels in rat basal ganglia: implications for the treatment of levodopa-induced dyskinesias. The European Journal of Neuroscience. 18: 1607-14. PMID 14511339 DOI: 10.1046/J.1460-9568.2003.02896.X |
0.542 |
|
| 2003 |
Fu J, Gaetani S, Oveisi F, Lo Verme J, Serrano A, RodrÃguez De Fonseca F, Rosengarth A, Luecke H, Di Giacomo B, Tarzia G, Piomelli D. Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha. Nature. 425: 90-3. PMID 12955147 DOI: 10.1038/Nature01921 |
0.319 |
|
| 2003 |
Tarzia G, Duranti A, Tontini A, Spadoni G, Mor M, Rivara S, Vincenzo Plazzi P, Kathuria S, Piomelli D. Synthesis and structure-activity relationships of a series of pyrrole cannabinoid receptor agonists. Bioorganic & Medicinal Chemistry. 11: 3965-73. PMID 12927857 DOI: 10.1016/S0968-0896(03)00413-9 |
0.307 |
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| 2003 |
Chen K, Ratzliff A, Hilgenberg L, Gulyás A, Freund TF, Smith M, Dinh TP, Piomelli D, Mackie K, Soltesz I. Long-term plasticity of endocannabinoid signaling induced by developmental febrile seizures. Neuron. 39: 599-611. PMID 12925275 DOI: 10.1016/S0896-6273(03)00499-9 |
0.725 |
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| 2003 |
Freund TF, Katona I, Piomelli D. Role of endogenous cannabinoids in synaptic signaling. Physiological Reviews. 83: 1017-66. PMID 12843414 DOI: 10.1152/Physrev.00004.2003 |
0.359 |
|
| 2003 |
Tarzia G, Duranti A, Tontini A, Piersanti G, Mor M, Rivara S, Plazzi PV, Park C, Kathuria S, Piomelli D. Design, synthesis, and structure-activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors. Journal of Medicinal Chemistry. 46: 2352-60. PMID 12773040 DOI: 10.1021/Jm021119G |
0.345 |
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| 2003 |
Kathuria S, Gaetani S, Fegley D, Valiño F, Duranti A, Tontini A, Mor M, Tarzia G, La Rana G, Calignano A, Giustino A, Tattoli M, Palmery M, Cuomo V, Piomelli D. Modulation of anxiety through blockade of anandamide hydrolysis. Nature Medicine. 9: 76-81. PMID 12461523 DOI: 10.1038/nm803 |
0.812 |
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| 2003 |
Leweke F, Giuffrida A, Gerth C, Klosterko¨tter J, Piomelli D. Evidence for a role of endogenous cannabinoids in schizophrenia Schizophrenia Research. 60: 101. DOI: 10.1016/S0920-9964(03)80828-9 |
0.456 |
|
| 2002 |
Schuel H, Burkman LJ, Lippes J, Crickard K, Forester E, Piomelli D, Giuffrida A. N-Acylethanolamines in human reproductive fluids. Chemistry and Physics of Lipids. 121: 211-27. PMID 12505702 DOI: 10.1016/S0009-3084(02)00158-5 |
0.539 |
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| 2002 |
Dinh TP, Freund TF, Piomelli D. A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation. Chemistry and Physics of Lipids. 121: 149-58. PMID 12505697 DOI: 10.1016/S0009-3084(02)00150-0 |
0.709 |
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| 2002 |
Gómez R, Navarro M, Ferrer B, Trigo JM, Bilbao A, Del Arco I, Cippitelli A, Nava F, Piomelli D, RodrÃguez de Fonseca F. A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9612-7. PMID 12417686 DOI: 10.1523/Jneurosci.22-21-09612.2002 |
0.351 |
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| 2002 |
Del Arco I, Navarro M, Bilbao A, Ferrer B, Piomelli D, RodrÃguez De Fonseca F. Attenuation of spontaneous opiate withdrawal in mice by the anandamide transport inhibitor AM404. European Journal of Pharmacology. 454: 103-4. PMID 12409011 DOI: 10.1016/S0014-2999(02)02483-4 |
0.308 |
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| 2002 |
Schäbitz WR, Giuffrida A, Berger C, Aschoff A, Schwaninger M, Schwab S, Piomelli D. Release of fatty acid amides in a patient with hemispheric stroke: a microdialysis study. Stroke; a Journal of Cerebral Circulation. 33: 2112-4. PMID 12154273 DOI: 10.1161/01.Str.0000023491.63693.18 |
0.493 |
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| 2002 |
Dinh TP, Carpenter D, Leslie FM, Freund TF, Katona I, Sensi SL, Kathuria S, Piomelli D. Brain monoglyceride lipase participating in endocannabinoid inactivation. Proceedings of the National Academy of Sciences of the United States of America. 99: 10819-24. PMID 12136125 DOI: 10.1073/Pnas.152334899 |
0.715 |
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| 2002 |
Leweke F, Giuffrida A, Gerth C, Faulhaber J, Klosterkötter K, Piomelli D. Endocannabinoids in schizophrenia and other psychiatric disorders European Psychiatry. 17: 156. DOI: 10.1016/S0924-9338(02)80679-4 |
0.443 |
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| 2001 |
Rodríguez De Fonseca F, Gorriti MA, Bilbao A, Escuredo L, García-Segura LM, Piomelli D, Navarro M. Role of the endogenous cannabinoid system as a modulator of dopamine transmission: implications for Parkinson's disease and schizophrenia. Neurotoxicity Research. 3: 23-35. PMID 15111259 DOI: 10.1007/Bf03033228 |
0.326 |
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| 2001 |
RodrÃguez de Fonseca F, Navarro M, Gómez R, Escuredo L, Nava F, Fu J, Murillo-RodrÃguez E, Giuffrida A, LoVerme J, Gaetani S, Kathuria S, Gall C, Piomelli D. An anorexic lipid mediator regulated by feeding. Nature. 414: 209-12. PMID 11700558 DOI: 10.1038/35102582 |
0.797 |
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| 2001 |
Stella N, Piomelli D. Receptor-dependent formation of endogenous cannabinoids in cortical neurons. European Journal of Pharmacology. 425: 189-96. PMID 11513837 DOI: 10.1016/S0014-2999(01)01182-7 |
0.584 |
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| 2001 |
Calignano A, La Rana G, Piomelli D. Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide. European Journal of Pharmacology. 419: 191-8. PMID 11426841 DOI: 10.1016/S0014-2999(01)00988-8 |
0.391 |
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| 2001 |
Giuffrida A, Beltramo M, Piomelli D. Mechanisms of endocannabinoid inactivation: biochemistry and pharmacology. The Journal of Pharmacology and Experimental Therapeutics. 298: 7-14. PMID 11408519 |
0.526 |
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| 2001 |
Piomelli D. The ligand that came from within. Trends in Pharmacological Sciences. 22: 17-9. PMID 11165666 DOI: 10.1016/S0165-6147(00)01602-3 |
0.364 |
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| 2001 |
Burkman L, Schuel H, Lippes J, Makriyannis A, Giuffrida A, Piomelli D. Endocannabinoids: Discovery of a unique signaling system for regulating sperm function and fertilization. Fertility and Sterility. 76: S202-S203. DOI: 10.1016/S0015-0282(01)02602-4 |
0.409 |
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| 2000 |
Giuffrida A, Piomelli D. The endocannabinoid system: a physiological perspective on its role in psychomotor control. Chemistry and Physics of Lipids. 108: 151-8. PMID 11106788 DOI: 10.1016/S0009-3084(00)00193-6 |
0.54 |
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| 2000 |
Calignano A, La Rana G, Loubet-Lescoulié P, Piomelli D. A role for the endogenous cannabinoid system in the peripheral control of pain initiation. Progress in Brain Research. 129: 471-82. PMID 11098711 DOI: 10.1016/S0079-6123(00)29034-1 |
0.361 |
|
| 2000 |
Calignano A, Kátona I, Désarnaud F, Giuffrida A, La Rana G, Mackie K, Freund TF, Piomelli D. Bidirectional control of airway responsiveness by endogenous cannabinoids. Nature. 408: 96-101. PMID 11081515 DOI: 10.1038/35040576 |
0.64 |
|
| 2000 |
Giuffrida A, Rodriguez de Fonseca F, Nava F, Loubet-Lescoulié P, Piomelli D. Elevated circulating levels of anandamide after administration of the transport inhibitor, AM404. European Journal of Pharmacology. 408: 161-8. PMID 11080522 DOI: 10.1016/S0014-2999(00)00786-X |
0.542 |
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| 2000 |
Piomelli D, Giuffrida A, Calignano A, RodrÃguez de Fonseca F. The endocannabinoid system as a target for therapeutic drugs. Trends in Pharmacological Sciences. 21: 218-24. PMID 10838609 DOI: 10.1016/S0165-6147(00)01482-6 |
0.555 |
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| 2000 |
Giuffrida A, RodrÃguez de Fonseca F, Piomelli D. Quantification of bioactive acylethanolamides in rat plasma by electrospray mass spectrometry. Analytical Biochemistry. 280: 87-93. PMID 10805525 DOI: 10.1006/Abio.2000.4509 |
0.483 |
|
| 2000 |
Giuffrida A, Désarnaud F, Piomelli D. Endogenous cannabinoid signaling and psychomotor disorders. Prostaglandins & Other Lipid Mediators. 61: 63-70. PMID 10785542 DOI: 10.1016/S0090-6980(00)00055-1 |
0.523 |
|
| 2000 |
Beltramo M, de Fonseca FR, Navarro M, Calignano A, Gorriti MA, Grammatikopoulos G, Sadile AG, Giuffrida A, Piomelli D. Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3401-7. PMID 10777802 DOI: 10.1523/Jneurosci.20-09-03401.2000 |
0.562 |
|
| 2000 |
La Rana G, Lobello R, Piomelli D, Calignano A. Endocannabinoids and Peripheral Pain Pharmacy and Pharmacology Communications. 6: 259-262. DOI: 10.1211/146080800128736042 |
0.329 |
|
| 2000 |
Piomelli D, Giuffrida A. Reply: cannabinoid paths to anti-diarrheal drugs Trends in Pharmacological Sciences. 21: 373. DOI: 10.1016/S0165-6147(00)01539-X |
0.532 |
|
| 1999 |
Straiker A, Stella N, Piomelli D, Mackie K, Karten HJ, Maguire G. Cannabinoid CB1 receptors and ligands in vertebrate retina: localization and function of an endogenous signaling system. Proceedings of the National Academy of Sciences of the United States of America. 96: 14565-70. PMID 10588745 DOI: 10.1073/Pnas.96.25.14565 |
0.718 |
|
| 1999 |
Leweke FM, Giuffrida A, Wurster U, Emrich HM, Piomelli D. Elevated endogenous cannabinoids in schizophrenia. Neuroreport. 10: 1665-9. PMID 10501554 DOI: 10.1097/00001756-199906030-00008 |
0.643 |
|
| 1999 |
Giuffrida A, Parsons LH, Kerr TM, RodrÃguez de Fonseca F, Navarro M, Piomelli D. Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. Nature Neuroscience. 2: 358-63. PMID 10204543 DOI: 10.1016/S0090-6980(99)90286-1 |
0.521 |
|
| 1999 |
Beltramo M, Piomelli D. Anandamide transport inhibition by the vanilloid agonist olvanil. European Journal of Pharmacology. 364: 75-8. PMID 9920187 DOI: 10.1016/S0014-2999(98)00821-8 |
0.307 |
|
| 1999 |
Maguire G, Straiker A, Chauder D, Haamedi SN, Piomelli D, Stella N, Lu QJ. Neural circuitry and plasticity in the adult vertebrate inner retina Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 1606: 65-72. DOI: 10.1007/BFb0098161 |
0.591 |
|
| 1998 |
Piomelli D, Beltramo M, Giuffrida A, Stella N. Endogenous cannabinoid signaling. Neurobiology of Disease. 5: 462-73. PMID 9974178 DOI: 10.1006/Nbdi.1998.0221 |
0.625 |
|
| 1998 |
Calignano A, La Rana G, Giuffrida A, Piomelli D. Control of pain initiation by endogenous cannabinoids. Nature. 394: 277-81. PMID 9685157 DOI: 10.1038/28393 |
0.554 |
|
| 1998 |
Giuffrida A, Piomelli D. Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma. Febs Letters. 422: 373-6. PMID 9498819 DOI: 10.1016/S0014-5793(98)00046-5 |
0.497 |
|
| 1997 |
Di Tomaso E, Cadas H, Gaillet S, Beltramo M, Desarnaud F, Venance L, Piomelli D. Endogenous lipids that activate cannabinoid receptors. Formation and inactivation. Advances in Experimental Medicine and Biology. 407: 335-40. PMID 9321973 DOI: 10.1007/978-1-4899-1813-0_50 |
0.351 |
|
| 1997 |
Stella N, Schweitzer P, Piomelli D. A second endogenous cannabinoid that modulates long-term potentiation. Nature. 388: 773-8. PMID 9285589 DOI: 10.1038/42015 |
0.581 |
|
| 1997 |
Beltramo M, Stella N, Calignano A, Lin SY, Makriyannis A, Piomelli D. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. Science (New York, N.Y.). 277: 1094-7. PMID 9262477 DOI: 10.1126/Science.277.5329.1094 |
0.585 |
|
| 1997 |
Stella N, Estellés A, Siciliano J, Tencé M, Desagher S, Piomelli D, Glowinski J, Prémont J. Interleukin-1 enhances the ATP-evoked release of arachidonic acid from mouse astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2939-46. PMID 9096130 DOI: 10.1523/Jneurosci.17-09-02939.1997 |
0.623 |
|
| 1997 |
Beltramo M, di Tomaso E, Piomelli D. Inhibition of anandamide hydrolysis in rat brain tissue by (E)-6-(bromomethylene) tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one. Febs Letters. 403: 263-7. PMID 9091314 DOI: 10.1016/S0014-5793(97)00061-6 |
0.336 |
|
| 1997 |
Cadas H, di Tomaso E, Piomelli D. Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1226-42. PMID 9006968 DOI: 10.1523/Jneurosci.17-04-01226.1997 |
0.313 |
|
| 1996 |
Cadas H, Gaillet S, Beltramo M, Venance L, Piomelli D. Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 3934-42. PMID 8656287 DOI: 10.1523/Jneurosci.16-12-03934.1996 |
0.324 |
|
| 1996 |
Lammers CH, Schweitzer P, Facchinetti P, Arrang JM, Madamba SG, Siggins GR, Piomelli D. Arachidonate 5-lipoxygenase and its activating protein: prominent hippocampal expression and role in somatostatin signaling. Journal of Neurochemistry. 66: 147-52. PMID 8522947 DOI: 10.1046/J.1471-4159.1996.66010147.X |
0.356 |
|
| 1996 |
Piomelli D, Beltramo M, Cadas H, Di Tomaso E, Stella N. Release and inactivation of endogenous cannabinoid substances Biological Psychiatry. 39: 615-616. DOI: 10.1016/0006-3223(96)84337-X |
0.504 |
|
| 1995 |
Vial D, Piomelli D. Dopamine D2 receptors potentiate arachidonate release via activation of cytosolic, arachidonate-specific phospholipase A2. Journal of Neurochemistry. 64: 2765-72. PMID 7760057 DOI: 10.1046/J.1471-4159.1995.64062765.X |
0.333 |
|
| 1995 |
Venance L, Piomelli D, Glowinski J, Giaume C. Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes. Nature. 376: 590-4. PMID 7637807 DOI: 10.1038/376590a0 |
0.424 |
|
| 1994 |
Di Marzo V, Fontana A, Cadas H, Schinelli S, Cimino G, Schwartz JC, Piomelli D. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. Nature. 372: 686-91. PMID 7990962 DOI: 10.1038/372686a0 |
0.333 |
|
| 1993 |
Di Marzo V, Vial D, Sokoloff P, Schwartz JC, Piomelli D. Selection of alternative G-mediated signaling pathways at the dopamine D2 receptor by protein kinase C. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 4846-53. PMID 7693893 DOI: 10.1523/Jneurosci.13-11-04846.1993 |
0.357 |
|
| 1993 |
Sihra TS, Piomelli D, Nichols RA. Barium evokes glutamate release from rat brain synaptosomes by membrane depolarization: involvement of K+, Na+, and Ca2+ channels. Journal of Neurochemistry. 61: 1220-30. PMID 7690845 DOI: 10.1111/J.1471-4159.1993.Tb13612.X |
0.698 |
|
| 1993 |
Piomelli D. Arachidonic acid in cell signaling. Current Opinion in Cell Biology. 5: 274-80. PMID 7685181 DOI: 10.1016/0955-0674(93)90116-8 |
0.357 |
|
| 1992 |
Di Marzo V, Piomelli D. Participation of prostaglandin E2 in dopamine D2 receptor-dependent potentiation of arachidonic acid release. Journal of Neurochemistry. 59: 379-82. PMID 1351931 DOI: 10.1111/J.1471-4159.1992.Tb08915.X |
0.302 |
|
| 1992 |
Traiffort E, Ruat M, Arrang JM, Leurs R, Piomelli D, Schwartz JC. Expression of a cloned rat histamine H2 receptor mediating inhibition of arachidonate release and activation of cAMP accumulation. Proceedings of the National Academy of Sciences of the United States of America. 89: 2649-53. PMID 1313563 DOI: 10.1073/Pnas.89.7.2649 |
0.338 |
|
| 1991 |
Piomelli D. Metabolism of arachidonic acid in nervous system of marine mollusk Aplysia californica. The American Journal of Physiology. 260: R844-8. PMID 1903603 DOI: 10.1152/Ajpregu.1991.260.5.R844 |
0.314 |
|
| 1991 |
Piomelli D, Greengard P. Bidirectional control of phospholipase A2 activity by Ca2+/calmodulin-dependent protein kinase II, cAMP-dependent protein kinase, and casein kinase II. Proceedings of the National Academy of Sciences of the United States of America. 88: 6770-4. PMID 1650481 DOI: 10.1073/PNAS.88.15.6770 |
0.438 |
|
| 1990 |
Piomelli D, Greengard P. Lipoxygenase metabolites of arachidonic acid in neuronal transmembrane signalling. Trends in Pharmacological Sciences. 11: 367-73. PMID 2122564 DOI: 10.1016/0165-6147(90)90182-8 |
0.497 |
|
| 1989 |
Piomelli D, Feinmark SJ, Shapiro E, Schwartz JH. 12-keto-eicosatetraenoic acid. A biologically active eicosanoid in the nervous system of Aplysia. Annals of the New York Academy of Sciences. 559: 208-18. PMID 2774398 DOI: 10.1111/J.1749-6632.1989.Tb22610.X |
0.328 |
|
| 1989 |
Piomelli D, Wang JK, Sihra TS, Nairn AC, Czernik AJ, Greengard P. Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites. Proceedings of the National Academy of Sciences of the United States of America. 86: 8550-4. PMID 2554319 DOI: 10.1073/PNAS.86.21.8550 |
0.721 |
|
| 1989 |
Piomelli D, Shapiro E, Zipkin R, Schwartz JH, Feinmark SJ. Formation and action of 8-hydroxy-11,12-epoxy-5,9,14-icosatrienoic acid in Aplysia: a possible second messenger in neurons. Proceedings of the National Academy of Sciences of the United States of America. 86: 1721-5. PMID 2493649 DOI: 10.1073/Pnas.86.5.1721 |
0.304 |
|
| 1988 |
Shapiro E, Piomelli D, Feinmark S, Vogel S, Chin G, Schwartz JH. The role of arachidonic acid metabolites in signal transduction in an identified neural network mediating presynaptic inhibition in Aplysia. Cold Spring Harbor Symposia On Quantitative Biology. 53: 425-33. PMID 3151176 DOI: 10.1101/Sqb.1988.053.01.050 |
0.305 |
|
| 1987 |
Piomelli D, Shapiro E, Feinmark SJ, Schwartz JH. Metabolites of arachidonic acid in the nervous system of Aplysia: possible mediators of synaptic modulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 3675-86. PMID 3119791 DOI: 10.1523/Jneurosci.07-11-03675.1987 |
0.342 |
|
| 1987 |
Piomelli D, Volterra A, Dale N, Siegelbaum SA, Kandel ER, Schwartz JH, Belardetti F. Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells. Nature. 328: 38-43. PMID 2439918 DOI: 10.1038/328038A0 |
0.732 |
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