Year |
Citation |
Score |
2020 |
Shin DH, Kim M, Kim Y, Jun I, Jung J, Nam JH, Cheng MH, Lee MG. Bicarbonate permeation through anion channels: its role in health and disease. Pflugers Archiv : European Journal of Physiology. PMID 32621085 DOI: 10.1007/S00424-020-02425-X |
0.362 |
|
2020 |
Kim Y, Jun I, Shin DH, Yoon JG, Jung J, Park HW, Cheng MH, Bahar I, Whitcomb DC, Lee MG. Dynamic Regulation of Bicarbonate Permeability through CFTR Channel by WNK1 Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.2348 |
0.348 |
|
2019 |
Kim Y, Jun I, Shin DH, Yoon JG, Piao H, Jung J, Park HW, Cheng MH, Bahar I, Whitcomb DC, Lee MG. Regulation of CFTR Bicarbonate Channel Activity by WNK1: Implications for Pancreatitis and CFTR-related disorders. Cellular and Molecular Gastroenterology and Hepatology. PMID 31561038 DOI: 10.1016/J.Jcmgh.2019.09.003 |
0.321 |
|
2019 |
Cheng MH, Bahar I. Monoamine transporters: structure, intrinsic dynamics and allosteric regulation. Nature Structural & Molecular Biology. 26: 545-556. PMID 31270469 DOI: 10.1038/S41594-019-0253-7 |
0.339 |
|
2019 |
Cheng MH, Ponzoni L, Sorkina T, Lee JY, Zhang S, Sorkin A, Bahar I. Trimerization of dopamine transporter triggered by AIM-100 binding: Molecular mechanism and effect of mutations. Neuropharmacology. 107676. PMID 31228486 DOI: 10.1016/J.Neuropharm.2019.107676 |
0.348 |
|
2018 |
Ponzoni L, Zhang S, Cheng MH, Bahar I. Shared dynamics of LeuT superfamily members and allosteric differentiation by structural irregularities and multimerization. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29735731 DOI: 10.1098/Rstb.2017.0177 |
0.351 |
|
2017 |
Cheng MH, Kaya C, Bahar I. A Quantitative Assessment of the Energetics of Dopamine Translocation by Human Dopamine Transporter. The Journal of Physical Chemistry. B. PMID 29232131 DOI: 10.1021/Acs.Jpcb.7B10340 |
0.346 |
|
2017 |
Gur M, Cheng MH, Zomot E, Bahar I. Effect of Dimerization on the Dynamics of Neurotransmitter: Sodium Symporters. The Journal of Physical Chemistry. B. PMID 28118712 DOI: 10.1021/Acs.Jpcb.6B09876 |
0.325 |
|
2017 |
Kaya C, Cheng MH, Block ER, Sorkin A, Faeder JR, Bahar I. Effect of Spatial Complexity on Dopaminergic Signaling Revealed from Multiscale Simulations Biophysical Journal. 112: 135a. DOI: 10.1016/J.Bpj.2016.11.751 |
0.302 |
|
2015 |
Gur M, Zomot E, Cheng MH, Bahar I. Energy landscape of LeuT from molecular simulations. The Journal of Chemical Physics. 143: 243134. PMID 26723619 DOI: 10.1063/1.4936133 |
0.364 |
|
2015 |
Jun I, Cheng MH, Sim E, Jung J, Suh BL, Kim Y, Son H, Park K, Kim CH, Yoon JH, Whitcomb DC, Bahar I, Lee MG. Pore dilation increases the bicarbonate permeability of CFTR, ANO1, and glycine receptor anion channels. The Journal of Physiology. PMID 26663196 DOI: 10.1113/Jp271311 |
0.367 |
|
2015 |
Cheng MH, Bahar I. Molecular Mechanism of Dopamine Transport by Human Dopamine Transporter. Structure (London, England : 1993). 23: 2171-81. PMID 26481814 DOI: 10.1016/J.Str.2015.09.001 |
0.335 |
|
2015 |
Patel KM, Lin CY, Cheng MH. Effectiveness of Lymphatic Microsurgical Procedures in the Treatment of Primary Lymphedema. Plastic and Reconstructive Surgery. 136: 135-6. PMID 26397662 DOI: 10.1097/01.prs.0000472452.39097.ed |
0.369 |
|
2015 |
Cheng MH, Lin CY, Patel K. The Groin vs. Submental Vascularized Lymph Node Flaps: A Head-to-Head Comparison of Surgical Outcomes Following Treatment for Upper Limb Lymphedema. Plastic and Reconstructive Surgery. 136: 135. PMID 26397661 DOI: 10.1097/01.prs.0000472451.39097.36 |
0.382 |
|
2015 |
Patel KM, Lin CY, Cheng MH. A Prospective Evaluation of Lymphedema-Specific Quality-of-Life Outcomes Following Vascularized Lymph Node Transfer. Annals of Surgical Oncology. 22: 2424-30. PMID 25515196 DOI: 10.1245/s10434-014-4276-3 |
0.384 |
|
2015 |
Cheng MH, Bahar I. Visualization of Molecular Events from Dopamine-Binding to -Release by Human Dopamine Transporter Biophysical Journal. 108: 462a. DOI: 10.1016/J.Bpj.2014.11.2520 |
0.351 |
|
2014 |
Cheng MH, Bahar I. Complete mapping of substrate translocation highlights the role of LeuT N-terminal segment in regulating transport cycle. Plos Computational Biology. 10: e1003879. PMID 25299050 DOI: 10.1371/Journal.Pcbi.1003879 |
0.35 |
|
2014 |
Cheng MH, Bahar I. Complete Mapping of Substrate Translocation Implicates the Secondary Binding Site and Highlights the Significance of LeuT N-Terminal Segment in Regulating Transport Cycle Biophysical Journal. 106: 364a. DOI: 10.1016/J.Bpj.2013.11.2066 |
0.379 |
|
2013 |
Cheng MH, Bahar I. Coupled global and local changes direct substrate translocation by neurotransmitter-sodium symporter ortholog LeuT. Biophysical Journal. 105: 630-9. PMID 23931311 DOI: 10.1016/J.Bpj.2013.06.032 |
0.321 |
|
2013 |
Mowrey D, Cheng MH, Liu LT, Willenbring D, Lu X, Wymore T, Xu Y, Tang P. Asymmetric ligand binding facilitates conformational transitions in pentameric ligand-gated ion channels. Journal of the American Chemical Society. 135: 2172-80. PMID 23339564 DOI: 10.1021/Ja307275V |
0.395 |
|
2013 |
Tillman T, Cheng MH, Chen Q, Tang P, Xu Y. Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics. The Biochemical Journal. 449: 61-8. PMID 22978431 DOI: 10.1042/Bj20121072 |
0.405 |
|
2013 |
Mowrey DD, Cheng MH, Liu LT, Willenbring D, Lu X, Wymore T, Xu Y, Tang P. Does Symmetry of Ligand Occupancy Matter to Conformational Transitions of Pentameric Ligand Gated Ion Channels? Biophysical Journal. 104: 380a. DOI: 10.1016/J.Bpj.2012.11.2116 |
0.37 |
|
2012 |
Cheng MH, Coalson RD. Energetics and ion permeation characteristics in a glutamate-gated chloride (GluCl) receptor channel. The Journal of Physical Chemistry. B. 116: 13637-43. PMID 23088363 DOI: 10.1021/Jp3074915 |
0.398 |
|
2012 |
Cheng MH, Coalson RD. Molecular dynamics investigation of Cl- and water transport through a eukaryotic CLC transporter. Biophysical Journal. 102: 1363-71. PMID 22455919 DOI: 10.1016/J.Bpj.2012.01.056 |
0.348 |
|
2011 |
Coalson RD, Cheng MH. Discrete-state representation of ion permeation coupled to fast gating in a model of CLC-chloride channels: analytic estimation of the state-to-state rate constants. The Journal of Physical Chemistry. A. 115: 9633-42. PMID 21692490 DOI: 10.1021/Jp200749S |
0.346 |
|
2010 |
Cheng MH, Coalson RD, Tang P. Molecular dynamics and brownian dynamics investigation of ion permeation and anesthetic halothane effects on a proton-gated ion channel. Journal of the American Chemical Society. 132: 16442-9. PMID 20979415 DOI: 10.1021/Ja105001A |
0.4 |
|
2010 |
Chen Q, Cheng MH, Xu Y, Tang P. Anesthetic binding in a pentameric ligand-gated ion channel: GLIC. Biophysical Journal. 99: 1801-9. PMID 20858424 DOI: 10.1016/J.Bpj.2010.07.023 |
0.383 |
|
2010 |
Coalson RD, Cheng MH. Discrete-state representation of ion permeation coupled to fast gating in a model of ClC chloride channels: comparison to multi-ion continuous space Brownian dynamics simulations. The Journal of Physical Chemistry. B. 114: 1424-33. PMID 20050590 DOI: 10.1021/Jp907965B |
0.358 |
|
2010 |
Cheng MH, Xu Y, Coalson RD, Tang∗ P. Molecular Dynamics Investigation of Anesthetic Halothane Interactions with the Proton-Gated Ion Channel GLIC Biophysical Journal. 98: 703a. DOI: 10.1016/J.Bpj.2009.12.3857 |
0.414 |
|
2010 |
Chen Q, Cheng MH, Stevenson H, Xu Y, Tang P. Multisite Binding of Anesthetics to GLIC, a Pentameric Ligand-Gated Ion Channel Biophysical Journal. 98: 702a-703a. DOI: 10.1016/J.Bpj.2009.12.3855 |
0.345 |
|
2009 |
Cheng MH, Xu Y, Tang P. Anionic lipid and cholesterol interactions with alpha4beta2 nAChR: insights from MD simulations. The Journal of Physical Chemistry. B. 113: 6964-70. PMID 19419220 DOI: 10.1021/Jp900714B |
0.347 |
|
2009 |
Yu AS, Cheng MH, Angelow S, Günzel D, Kanzawa SA, Schneeberger EE, Fromm M, Coalson RD. Molecular basis for cation selectivity in claudin-2-based paracellular pores: identification of an electrostatic interaction site. The Journal of General Physiology. 133: 111-27. PMID 19114638 DOI: 10.1083/Jcb1841Oia3 |
0.325 |
|
2009 |
Cheng MH, Haddadian E, Xu Y, Tang P. Interactions between POPA and a4b2 nAChR: Insight from MD Simulations Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.3225 |
0.379 |
|
2008 |
Haddadian EJ, Cheng MH, Coalson RD, Xu Y, Tang P. In silico models for the human alpha4beta2 nicotinic acetylcholine receptor. The Journal of Physical Chemistry. B. 112: 13981-90. PMID 18847252 DOI: 10.1021/Jp804868S |
0.376 |
|
2008 |
Cheng MH, Coalson RD, Cascio M, Kurnikova M. Computational prediction of ion permeation characteristics in the glycine receptor modified by photo-sensitive compounds. Journal of Computer-Aided Molecular Design. 22: 563-70. PMID 18368498 DOI: 10.1007/S10822-008-9200-0 |
0.335 |
|
2008 |
Cheng MH, Coalson RD, Cascio M. Molecular dynamics simulations of ethanol binding to the transmembrane domain of the glycine receptor: implications for the channel potentiation mechanism. Proteins. 71: 972-81. PMID 18004757 DOI: 10.1002/Prot.21784 |
0.314 |
|
2007 |
Cheng MH, Mamonov AB, Dukes JW, Coalson RD. Modeling the fast gating mechanism in the ClC-0 chloride channel. The Journal of Physical Chemistry. B. 111: 5956-65. PMID 17487993 DOI: 10.1021/Jp063993H |
0.395 |
|
2007 |
Cheng MH, Cascio M, Coalson RD. Homology modeling and molecular dynamics simulations of the alpha1 glycine receptor reveals different states of the channel. Proteins. 68: 581-93. PMID 17469203 DOI: 10.1002/Prot.21435 |
0.328 |
|
2005 |
Cheng MH, Coalson RD. An accurate and efficient empirical approach for calculating the dielectric self-energy and ion-ion pair potential in continuum models of biological ion channels. The Journal of Physical Chemistry. B. 109: 488-98. PMID 16851040 DOI: 10.1021/Jp047438W |
0.335 |
|
2005 |
Cheng MH, Cascio M, Coalson RD. Theoretical studies of the M2 transmembrane segment of the glycine receptor: models of the open pore structure and current-voltage characteristics. Biophysical Journal. 89: 1669-80. PMID 15951389 DOI: 10.1529/Biophysj.105.060368 |
0.388 |
|
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