| Year |
Citation |
Score |
| 2019 |
Ardestani A, Li S, Annamalai K, Lupse B, Geravandi S, Dobrowolski A, Yu S, Zhu S, Baguley TD, Surakattula M, Oetjen J, Hauberg-Lotte L, Herranz R, Awal S, Altenhofen D, et al. Neratinib protects pancreatic beta cells in diabetes. Nature Communications. 10: 5015. PMID 31676778 DOI: 10.1038/S41467-019-12880-5 |
0.409 |
|
| 2018 |
Zhong L, Tran T, Baguley TD, Lee SJ, Henke A, To A, Li S, Yu S, Grieco FA, Roland J, Schultz PG, Eizirik DL, Rogers N, Chartterjee AK, Tremblay MS, et al. A Novel Inhibitor of iNOS Dimerization Protects Against Cytokine-Induced Rat β-cell Dysfunction. British Journal of Pharmacology. PMID 29888783 DOI: 10.1111/Bph.14388 |
0.369 |
|
| 2017 |
Tjin CC, Otley KD, Baguley TD, Kurup P, Xu J, Nairn AC, Lombroso PJ, Ellman JA. Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases. Acs Central Science. 3: 1322-1328. PMID 29296673 DOI: 10.1021/Acscentsci.7B00486 |
0.521 |
|
| 2016 |
Xu J, Hartley BJ, Kurup P, Phillips A, Topol A, Xu M, Ononenyi C, Foscue E, Ho SM, Baguley TD, Carty N, Barros CS, Müller U, Gupta S, Gochman P, et al. Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models. Molecular Psychiatry. PMID 27752082 DOI: 10.1038/mp.2016.163 |
0.344 |
|
| 2015 |
Xu J, Kurup P, Baguley TD, Foscue E, Ellman JA, Nairn AC, Lombroso PJ. Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice. Cellular and Molecular Life Sciences : Cmls. PMID 26450419 DOI: 10.1007/S00018-015-2057-1 |
0.528 |
|
| 2015 |
Xu J, Kurup P, Azkona G, Baguley TD, Saavedra A, Nairn AC, Ellman JA, Pérez-Navarro E, Lombroso PJ. Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels. Journal of Neurochemistry. PMID 26316048 DOI: 10.1111/Jnc.13295 |
0.543 |
|
| 2015 |
Azkona G, Saavedra A, Aira Z, Aluja D, Xifró X, Baguley T, Alberch J, Ellman JA, Lombroso PJ, Azkue JJ, Pérez-Navarro E. STEP modulates nociception: evidences from genetic deletion and pharmacological inhibition. Pain. PMID 26270590 DOI: 10.1097/J.Pain.0000000000000329 |
0.511 |
|
| 2015 |
Baguley TD, Nairn AC, Lombroso PJ, Ellman JA. Synthesis of benzopentathiepin analogs and their evaluation as inhibitors of the phosphatase STEP. Bioorganic & Medicinal Chemistry Letters. 25: 1044-6. PMID 25666825 DOI: 10.1016/J.Bmcl.2015.01.020 |
0.677 |
|
| 2014 |
Xu J, Chatterjee M, Baguley TD, Brouillette J, Kurup P, Ghosh D, Kanyo J, Zhang Y, Seyb K, Ononenyi C, Foscue E, Anderson GM, Gresack J, Cuny GD, Glicksman MA, et al. Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease. Plos Biology. 12: e1001923. PMID 25093460 DOI: 10.1371/Journal.Pbio.1001923 |
0.614 |
|
| 2013 |
Baguley TD, Xu HC, Chatterjee M, Nairn AC, Lombroso PJ, Ellman JA. Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase. Journal of Medicinal Chemistry. 56: 7636-50. PMID 24083656 DOI: 10.1021/Jm401037H |
0.704 |
|
| 2011 |
Buesking AW, Baguley TD, Ellman JA. Asymmetric synthesis of amines by the Knochel-type MgCl2-enhanced addition of benzyl zinc reagents to N-tert-butanesulfinyl aldimines. Organic Letters. 13: 964-7. PMID 21306151 DOI: 10.1021/Ol103002T |
0.633 |
|
| 2009 |
Rawls KA, Lang PT, Takeuchi J, Imamura S, Baguley TD, Grundner C, Alber T, Ellman JA. Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA. Bioorganic & Medicinal Chemistry Letters. 19: 6851-4. PMID 19889539 DOI: 10.1016/J.Bmcl.2009.10.090 |
0.689 |
|
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