Linda L. Demer, M.d., Ph.D. - Publications

Affiliations: 
Bioengineering University of California, Los Angeles, Los Angeles, CA 

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Xian JZ, Lu M, Fong F, Qiao R, Patel NR, Abeydeera D, Iriana S, Demer LL, Tintut Y. Statin Effects on Vascular Calcification: Microarchitectural Changes in Aortic Calcium Deposits in Aged Hyperlipidemic Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120315737. PMID 33472400 DOI: 10.1161/ATVBAHA.120.315737  0.56
2020 Fong F, Xian J, Demer LL, Tintut Y. Serotonin receptor type 2B activation augments TNF-α-induced matrix mineralization in murine valvular interstitial cells. Journal of Cellular Biochemistry. PMID 32901992 DOI: 10.1002/Jcb.29847  0.56
2020 Hsu JJ, Fong F, Patel R, Qiao R, Lo K, Soundia A, Chang CC, Le V, Tseng CH, Demer LL, Tintut Y. Changes in microarchitecture of atherosclerotic calcification assessed by F-NaF PET and CT after a progressive exercise regimen in hyperlipidemic mice. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. PMID 31897996 DOI: 10.1007/S12350-019-02004-3  0.56
2019 Sallam T, Tintut Y, Demer LL. Regulation of calcific vascular and valvular disease by nuclear receptors. Current Opinion in Lipidology. PMID 31369409 DOI: 10.1097/Mol.0000000000000632  0.56
2019 Demer LL, Tintut Y. Interactive and Multifactorial Mechanisms of Calcific Vascular and Valvular Disease. Trends in Endocrinology and Metabolism: Tem. PMID 31279666 DOI: 10.1016/J.Tem.2019.06.001  0.56
2019 Hsu JJ, Vedula V, Baek KI, Chen C, Chen J, Chou MI, Lam J, Subhedar S, Wang J, Ding Y, Chang CC, Lee J, Demer LL, Tintut Y, Marsden AL, et al. Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation. Jci Insight. 5. PMID 30973827 DOI: 10.1172/Jci.Insight.124460  0.56
2018 Tintut Y, Hsu JJ, Demer LL. Lipoproteins in Cardiovascular Calcification: Potential Targets and Challenges. Frontiers in Cardiovascular Medicine. 5: 172. PMID 30533416 DOI: 10.3389/Fcvm.2018.00172  0.56
2018 Ding Y, Ma J, Langenbacher AD, Baek KI, Lee J, Chang CC, Hsu JJ, Kulkarni RP, Belperio J, Shi W, Ranjbarvaziri S, Ardehali R, Tintut Y, Demer LL, Chen JN, et al. Multiscale light-sheet for rapid imaging of cardiopulmonary system. Jci Insight. 3. PMID 30135307 DOI: 10.1172/Jci.Insight.121396  0.56
2018 Demer LL, Hsu JJ, Tintut Y. Steroid Hormone Vitamin D: Implications for Cardiovascular Disease. Circulation Research. 122: 1576-1585. PMID 29798901 DOI: 10.1161/Circresaha.118.311585  0.56
2018 Hsu JJ, Lu J, Umar S, Lee JT, Kulkarni R, Ding Y, Chang CC, Hsiai TK, Hokugo A, Gkouveris I, Tetradis S, Nishimura I, Demer LL, Tintut Y. Effects of teriparatide on morphology of aortic calcification in aged hyperlipidemic mice. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29451816 DOI: 10.1152/Ajpheart.00718.2017  0.56
2017 Demer LL, Tintut Y, Nguyen KL, Hsiai T, Lee JT. Rigor and Reproducibility in Analysis of Vascular Calcification. Circulation Research. 120: 1240-1242. PMID 28408452 DOI: 10.1161/Circresaha.116.310326  0.56
2016 Demer LL, Tintut Y. Evolutionary approach sheds light on the significance of vascular calcification. Trends in Cardiovascular Medicine. PMID 27499040 DOI: 10.1016/J.Tcm.2016.06.001  0.56
2016 Hsu JJ, Lim J, Tintut Y, Demer LL. Cell-matrix mechanics and pattern formation in inflammatory cardiovascular calcification. Heart (British Cardiac Society). PMID 27406839 DOI: 10.1136/Heartjnl-2016-309667  0.56
2016 Lim J, Ehsanipour A, Hsu JJ, Lu J, Pedego T, Wu A, Walthers CM, Demer LL, Seidlits SK, Tintut Y. Inflammation Drives Retraction, Stiffening, and Nodule Formation via Cytoskeletal Machinery in a Three-Dimensional Culture Model of Aortic Stenosis. The American Journal of Pathology. PMID 27392969 DOI: 10.1016/J.Ajpath.2016.05.003  0.56
2016 Tintut Y, Demer LL. COMP-lex Mechanics: Matricrine Signaling. Circulation Research. 119: 184-6. PMID 27390328 DOI: 10.1161/Circresaha.116.309121  0.56
2016 Packard RR, Zhang X, Luo Y, Ma T, Jen N, Ma J, Demer LL, Zhou Q, Sayre JW, Li R, Tai YC, Hsiai TK. Two-Point Stretchable Electrode Array for Endoluminal Electrochemical Impedance Spectroscopy Measurements of Lipid-Laden Atherosclerotic Plaques. Annals of Biomedical Engineering. PMID 26857007 DOI: 10.1007/S10439-016-1559-9  0.56
2015 Lim JJ, Li X, Lu J, Pedego TM, Demer L, Tintut Y. Protective Role of Smad6 in Inflammation-Induced Valvular Cell Calcification. Journal of Cellular Biochemistry. PMID 25864564 DOI: 10.1002/Jcb.25186  0.56
2015 Tintut Y, Demer LL. Exosomes: nanosized cellular messages. Circulation Research. 116: 1281-3. PMID 25858057 DOI: 10.1161/Circresaha.115.306324  0.56
2015 Demer LL, Tintut Y. The leading edge of vascular calcification. Trends in Cardiovascular Medicine. 25: 275-7. PMID 25572012 DOI: 10.1016/J.Tcm.2014.11.010  0.56
2015 Demer LL, Boström KI. Conflicting forces of warfarin and matrix gla protein in the artery wall. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 9-10. PMID 25520520 DOI: 10.1161/Atvbaha.114.304793  0.56
2014 Yutzey KE, Demer LL, Body SC, Huggins GS, Towler DA, Giachelli CM, Hofmann-Bowman MA, Mortlock DP, Rogers MB, Sadeghi MM, Aikawa E. Calcific aortic valve disease: a consensus summary from the Alliance of Investigators on Calcific Aortic Valve Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2387-93. PMID 25189570 DOI: 10.1161/Atvbaha.114.302523  0.56
2014 Demer LL, Tintut Y. Inflammatory, metabolic, and genetic mechanisms of vascular calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 715-23. PMID 24665125 DOI: 10.1161/Atvbaha.113.302070  0.56
2014 van Venrooij NA, Pereira RC, Tintut Y, Fishbein MC, Tumber N, Demer LL, Salusky IB, Wesseling-Perry K. FGF23 protein expression in coronary arteries is associated with impaired kidney function. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 29: 1525-32. PMID 24459137 DOI: 10.1093/Ndt/Gft523  0.56
2014 Tintut Y, Demer LL. Effects of bioactive lipids and lipoproteins on bone. Trends in Endocrinology and Metabolism: Tem. 25: 53-9. PMID 24183940 DOI: 10.1016/J.Tem.2013.10.001  0.56
2014 Li X, Garcia J, Lu J, Iriana S, Kalajzic I, Rowe D, Demer LL, Tintut Y. Roles of parathyroid hormone (PTH) receptor and reactive oxygen species in hyperlipidemia-induced PTH resistance in preosteoblasts. Journal of Cellular Biochemistry. 115: 179-88. PMID 24038594 DOI: 10.1002/Jcb.24648  0.56
2013 Heistad DD, Shanahan C, Demer LL. Introduction to the Compendium on calcific aortic valve disease. Circulation Research. 113: 176-8. PMID 23833291 DOI: 10.1161/Circresaha.113.301833  0.56
2013 Lu J, Cheng H, Atti E, Shih DM, Demer LL, Tintut Y. Role of paraoxonase-1 in bone anabolic effects of parathyroid hormone in hyperlipidemic mice. Biochemical and Biophysical Research Communications. 431: 19-24. PMID 23291186 DOI: 10.1016/J.Bbrc.2012.12.114  0.56
2013 Sallam T, Cheng H, Demer LL, Tintut Y. Regulatory circuits controlling vascular cell calcification. Cellular and Molecular Life Sciences : Cmls. 70: 3187-97. PMID 23269436 DOI: 10.1007/S00018-012-1231-Y  0.56
2012 Wong MN, Nguyen TP, Chen TH, Hsu JJ, Zeng X, Saw A, Demer EM, Zhao X, Tintut Y, Demer LL. Preferred mitotic orientation in pattern formation by vascular mesenchymal cells. American Journal of Physiology. Heart and Circulatory Physiology. 303: H1411-7. PMID 23064835 DOI: 10.1152/Ajpheart.00625.2012  0.56
2012 Morony S, Sage AP, Corbin T, Lu J, Tintut Y, Demer LL. Enhanced mineralization potential of vascular cells from SM2α-rankltg mice Calcified Tissue International. 91: 379-386. PMID 23052229 DOI: 10.1007/S00223-012-9655-9  0.56
2012 Chen TH, Zhu X, Pan L, Zeng X, Garfinkel A, Tintut Y, Demer LL, Zhao X, Ho CM. Directing tissue morphogenesis via self-assembly of vascular mesenchymal cells. Biomaterials. 33: 9019-26. PMID 23010575 DOI: 10.1016/J.Biomaterials.2012.08.067  0.56
2012 Cheng H, Reddy A, Sage A, Lu J, Garfinkel A, Tintut Y, Demer LL. Focal high cell density generates a gradient of patterns in self-organizing vascular mesenchymal cells. Journal of Vascular Research. 49: 441-6. PMID 22797747 DOI: 10.1159/000339568  0.56
2012 Chen TH, Guo C, Zhao X, Yao Y, Boström KI, Wong MN, Tintut Y, Demer LL, Ho CM, Garfinkel A. Patterns of periodic holes created by increased cell motility. Interface Focus. 2: 457-64. PMID 22649581 DOI: 10.1098/Rsfs.2012.0001  0.56
2012 Chen TH, Hsu JJ, Zhao X, Guo C, Wong MN, Huang Y, Li Z, Garfinkel A, Ho CM, Tintut Y, Demer LL. Left-right symmetry breaking in tissue morphogenesis via cytoskeletal mechanics. Circulation Research. 110: 551-9. PMID 22223355 DOI: 10.1161/Circresaha.111.255927  0.56
2012 Li R, Mittelstein D, Lee J, Fang K, Majumdar R, Tintut Y, Demer LL, Hsiai TK. A dynamic model of calcific nodule destabilization in response to monocyte- and oxidized lipid-induced matrix metalloproteinases. American Journal of Physiology. Cell Physiology. 302: C658-65. PMID 22031601 DOI: 10.1152/Ajpcell.00313.2011  0.56
2012 Pirih F, Lu J, Ye F, Bezouglaia O, Atti E, Ascenzi MG, Tetradis S, Demer L, Aghaloo T, Tintut Y. Adverse effects of hyperlipidemia on bone regeneration and strength Journal of Bone and Mineral Research. 27: 309-318. PMID 21987408 DOI: 10.1002/Jbmr.541  0.56
2012 Chen TH, Wong M, Tintut Y, Demer LL, Ho CM. Cell pattern formation controlled by microscale interfaces Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 933-936. DOI: 10.1109/MEMSYS.2012.6170339  0.56
2012 Demer L, Tintut Y. Chapter 106 – Vascular Calcification Musclefundamental Biology and Mechanisms of Disease. 1383-1389. DOI: 10.1016/B978-0-12-381510-1.00106-X  0.56
2011 Rajamannan NM, Evans FJ, Aikawa E, Grande-Allen KJ, Demer LL, Heistad DD, Simmons CA, Masters KS, Mathieu P, O'Brien KD, Schoen FJ, Towler DA, Yoganathan AP, Otto CM. Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update. Circulation. 124: 1783-91. PMID 22007101 DOI: 10.1161/Circulationaha.110.006767  0.56
2011 Geng Y, Hsu JJ, Lu J, Ting TC, Miyazaki M, Demer LL, Tintut Y. Role of cellular cholesterol metabolism in vascular cell calcification. The Journal of Biological Chemistry. 286: 33701-6. PMID 21835914 DOI: 10.1074/Jbc.M111.269639  0.56
2011 Demer L, Tintut Y. The roles of lipid oxidation products and receptor activator of nuclear factor-κb signaling in atherosclerotic calcification Circulation Research. 108: 1482-1493. PMID 21659652 DOI: 10.1161/Circresaha.110.234245  0.56
2011 Towler DA, Demer LL. Thematic series on the pathobiology of vascular calcification: an introduction. Circulation Research. 108: 1378-80. PMID 21617134 DOI: 10.1161/Circresaha.110.234419  0.56
2011 Sage AP, Lu J, Atti E, Tetradis S, Ascenzi MG, Adams DJ, Demer LL, Tintut Y. Hyperlipidemia induces resistance to PTH bone anabolism in mice via oxidized lipids. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1197-206. PMID 21611962 DOI: 10.1002/Jbmr.312  0.56
2011 Ting TC, Miyazaki-Anzai S, Masuda M, Levi M, Demer LL, Tintut Y, Miyazaki M. Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cells. The Journal of Biological Chemistry. 286: 23938-49. PMID 21596756 DOI: 10.1074/Jbc.M111.237065  0.56
2011 Tintut Y, Demer L. Editorial: The hemosteoblast: Friend or foe? Circulation Research. 108: 1038-1039. PMID 21527740 DOI: 10.1161/Circresaha.111.244665  0.56
2011 Byon CH, Sun Y, Chen J, Yuan K, Mao X, Heath JM, Anderson PG, Tintut Y, Demer LL, Wang D, Chen Y. Runx2-upregulated receptor activator of nuclear factor κB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1387-96. PMID 21454810 DOI: 10.1161/Atvbaha.110.222547  0.56
2011 Sage AP, Lu J, Tintut Y, Demer LL. Hyperphosphatemia-induced nanocrystals upregulate the expression of bone morphogenetic protein-2 and osteopontin genes in mouse smooth muscle cells in vitro. Kidney International. 79: 414-22. PMID 20944546 DOI: 10.1038/Ki.2010.390  0.56
2011 Sage AP, Tintut Y, Demer LL. The authors reply: Kidney International. 79: 921. DOI: 10.1038/Ki.2010.562  0.56
2010 Sage AP, Tintut Y, Demer LL. Regulatory mechanisms in vascular calcification. Nature Reviews. Cardiology. 7: 528-36. PMID 20664518 DOI: 10.1615/Critreveukargeneexpr.V10.I2.40  0.56
2010 Tseng W, Graham LS, Geng Y, Reddy A, Lu J, Effros RB, Demer L, Tintut Y. PKA-induced receptor activator of NF-κB ligand (RANKL) expression in vascular cells mediates osteoclastogenesis but not matrix calcification Journal of Biological Chemistry. 285: 29925-29931. PMID 20663885 DOI: 10.1074/Jbc.M110.117366  0.56
2010 Demer L, Tintut Y. The bone-vascular axis in chronic kidney disease Current Opinion in Nephrology and Hypertension. 19: 349-353. PMID 20508522 DOI: 10.1097/Mnh.0B013E32833A3D67  0.56
2010 Tseng W, Lu J, Bishop GA, Watson AD, Sage AP, Demer L, Tintut Y. Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids. Journal of Lipid Research. 51: 1010-6. PMID 19965598 DOI: 10.1194/Jlr.M001099  0.56
2009 Sage A, Tintut Y, Garfinkel A, Demer L. Systems biology of vascular calcification. Trends in Cardiovascular Medicine. 19: 118-23. PMID 19818947 DOI: 10.1016/J.Tcm.2009.07.002  0.56
2009 Graham LS, Parhami F, Tintut Y, Kitchen CM, Demer LL, Effros RB. Oxidized lipids enhance RANKL production by T lymphocytes: implications for lipid-induced bone loss. Clinical Immunology (Orlando, Fla.). 133: 265-75. PMID 19699688 DOI: 10.1016/J.Clim.2009.07.011  0.56
2009 Demer LL, Tintut Y. Mechanisms linking osteoporosis with cardiovascular calcification. Current Osteoporosis Reports. 7: 42-6. PMID 19631027 DOI: 10.1007/S11914-009-0008-1  0.56
2009 Hoshino T, Chow LA, Hsu JJ, Perlowski AA, Abedin M, Tobis J, Tintut Y, Mal AK, Klug WS, Demer LL. Mechanical stress analysis of a rigid inclusion in distensible material: a model of atherosclerotic calcification and plaque vulnerability. American Journal of Physiology. Heart and Circulatory Physiology. 297: H802-10. PMID 19542489 DOI: 10.1152/Ajpheart.00318.2009  0.56
2009 Hsu JJ, Lu J, Huang MS, Geng Y, Sage AP, Bradley MN, Tontonoz P, Demer LL, Tintut Y. T0901317, an LXR agonist, augments PKA-induced vascular cell calcification. Febs Letters. 583: 1344-8. PMID 19327357 DOI: 10.1016/J.Febslet.2009.03.039  0.56
2008 Demer LL, Sage AP, Tintut Y. Nanoscale architecture in atherosclerotic calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1882-4. PMID 18946051 DOI: 10.1161/Atvbaha.108.175711  0.56
2008 Huang MS, Sage AP, Lu J, Demer LL, Tintut Y. Phosphate and pyrophosphate mediate PKA-induced vascular cell calcification. Biochemical and Biophysical Research Communications. 374: 553-8. PMID 18655772 DOI: 10.1016/J.Bbrc.2008.07.062  0.56
2008 Hsu JJ, Tintut Y, Demer LL. Vitamin D and osteogenic differentiation in the artery wall. Clinical Journal of the American Society of Nephrology : Cjasn. 3: 1542-7. PMID 18562594 DOI: 10.2215/Cjn.01220308  0.56
2008 Demer LL, Tintut Y. Vascular calcification: pathobiology of a multifaceted disease. Circulation. 117: 2938-48. PMID 18519861 DOI: 10.1161/Circulationaha.107.743161  0.56
2008 Huang MS, Lu J, Ivanov Y, Sage AP, Tseng W, Demer LL, Tintut Y. Hyperlipidemia impairs osteoanabolic effects of PTH. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 1672-9. PMID 18505371 DOI: 10.1359/Jbmr.080513  0.56
2008 Hsu JJ, Tintut Y, Demer LL. Murine models of atherosclerotic calcification. Current Drug Targets. 9: 224-8. PMID 18336241 DOI: 10.2174/138945008783755539  0.56
2008 Morony S, Tintut Y, Zhang Z, Cattley RC, Van G, Dwyer D, Stolina M, Kostenuik PJ, Demer LL. Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr(-/-) mice. Circulation. 117: 411-20. PMID 18172035 DOI: 10.1161/Circulationaha.107.707380  0.56
2008 Demer LL, Tintut Y. A matter of degree: a commentary on "Influence of oxidized low-density lipoproteins (LDL) on the viability of osteoblastic cells". Free Radical Biology & Medicine. 44: 504-5. PMID 18005672 DOI: 10.1016/J.Freeradbiomed.2007.10.039  0.56
2008 Morony S, Dwyer D, Stolina M, Kostenuik PJ, Tintut Y, Zhang Z, Demer LL, Cattley RC, Van G. Response to letter regarding article, "Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr (-'-) mice" Circulation. 118: e19. DOI: 10.1161/Circulationaha.108.782649  0.56
2008 Yochelis A, Tintut Y, Demer LL, Garfinkel A. The formation of labyrinths, spots and stripe patterns in a biochemical approach to cardiovascular calcification New Journal of Physics. 10. DOI: 10.1088/1367-2630/10/5/055002  0.56
2007 Huang MS, Morony S, Lu J, Zhang Z, Bezouglaia O, Tseng W, Tetradis S, Demer LL, Tintut Y. Atherogenic phospholipids attenuate osteogenic signaling by BMP-2 and parathyroid hormone in osteoblasts. The Journal of Biological Chemistry. 282: 21237-43. PMID 17522049 DOI: 10.1074/Jbc.M701341200  0.56
2007 Jaffe IZ, Tintut Y, Newfell BG, Demer LL, Mendelsohn ME. Mineralocorticoid receptor activation promotes vascular cell calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 799-805. PMID 17234727 DOI: 10.1161/01.Atv.0000258414.59393.89  0.56
2006 Tintut Y, Demer L. Role of osteoprotegerin and its ligands and competing receptors in atherosclerotic calcification Journal of Investigative Medicine. 54: 395-401. PMID 17169261 DOI: 10.2310/6650.2006.06019  0.56
2006 Lin TC, Tintut Y, Lyman A, Mack W, Demer LL, Hsiai TK. Mechanical response of a calcified plaque model to fluid shear force. Annals of Biomedical Engineering. 34: 1535-41. PMID 17006755 DOI: 10.1007/S10439-006-9182-9  0.56
2006 Demer LL, Tintut Y. Pitting phosphate transport inhibitors against vascular calcification. Circulation Research. 98: 857-9. PMID 16614308 DOI: 10.1161/01.Res.0000219673.71778.Df  0.56
2006 Abedin M, Lim J, Tang TB, Park D, Demer LL, Tintut Y. N-3 fatty acids inhibit vascular calcification via the p38-mitogen-activated protein kinase and peroxisome proliferator-activated receptor-gamma pathways. Circulation Research. 98: 727-9. PMID 16514067 DOI: 10.1161/01.Res.0000216009.68958.E6  0.56
2005 Demer LL, Tintut Y. Return to ectopia: stem cells in the artery wall. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1307-8. PMID 15980267 DOI: 10.1161/01.Atv.0000172633.74942.E6  0.56
2005 Tintut Y, Abedin M, Cho J, Choe A, Lim J, Demer LL. Regulation of RANKL-induced osteoclastic differentiation by vascular cells. Journal of Molecular and Cellular Cardiology. 39: 389-93. PMID 15893766 DOI: 10.1016/J.Yjmcc.2005.03.019  0.56
2005 Radcliff K, Tang TB, Lim J, Zhang Z, Abedin M, Demer LL, Tintut Y. Insulin-like growth factor-I regulates proliferation and osteoblastic differentiation of calcifying vascular cells via extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase pathways. Circulation Research. 96: 398-400. PMID 15692088 DOI: 10.1161/01.Res.0000157671.47477.71  0.56
2004 Demer LL, Abedin M. Skeleton key to vascular disease. Journal of the American College of Cardiology. 44: 1977-9. PMID 15542279 DOI: 10.1016/J.Jacc.2004.08.032  0.56
2004 Abedin M, Tintut Y, Demer LL. Mesenchymal stem cells and the artery wall. Circulation Research. 95: 671-6. PMID 15459088 DOI: 10.1161/01.Res.0000143421.27684.12  0.56
2004 Garfinkel A, Tintut Y, Petrasek D, Boström K, Demer LL. Pattern formation by vascular mesenchymal cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 9247-50. PMID 15197273 DOI: 10.1073/Pnas.0308436101  0.56
2004 Abedin M, Tintut Y, Demer LL. Vascular calcification: mechanisms and clinical ramifications. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1161-70. PMID 15155384 DOI: 10.1161/01.Atv.0000133194.94939.42  0.56
2004 Hsiai TK, Cho SK, Wong PK, Ing MH, Salazar A, Hama S, Navab M, Demer LL, Ho CM. Micro sensors: linking real-time oscillatory shear stress with vascular inflammatory responses. Annals of Biomedical Engineering. 32: 189-201. PMID 15008367 DOI: 10.1023/B:Abme.0000012739.88554.01  0.56
2004 Tintut Y, Morony S, Demer LL. Hyperlipidemia promotes osteoclastic potential of bone marrow cells ex vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: e6-10. PMID 14670933 DOI: 10.1161/01.Atv.0000112023.62695.7F  0.56
2003 Tintut Y, Alfonso Z, Saini T, Radcliff K, Watson K, Boström K, Demer LL. Multilineage potential of cells from the artery wall. Circulation. 108: 2505-10. PMID 14581408 DOI: 10.1161/01.Cir.0000096485.64373.C5  0.56
2003 Hsiai TK, Cho SK, Wong PK, Ing M, Salazar A, Sevanian A, Navab M, Demer LL, Ho CM. Monocyte recruitment to endothelial cells in response to oscillatory shear stress. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1648-57. PMID 12958171 DOI: 10.1096/Fj.02-1064Com  0.56
2003 Demer LL, Tintut Y. Mineral exploration: search for the mechanism of vascular calcification and beyond: the 2003 Jeffrey M. Hoeg Award lecture. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1739-43. PMID 12958041 DOI: 10.1161/01.Atv.0000093547.63630.0F  0.56
2003 Mody N, Tintut Y, Radcliff K, Demer LL. Vascular calcification and its relation to bone calcification: possible underlying mechanisms. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 10: 177-83. PMID 12673183 DOI: 10.1067/Mnc.2003.0012  0.56
2002 Parhami F, Mody N, Gharavi N, Ballard AJ, Tintut Y, Demer LL. Role of the cholesterol biosynthetic pathway in osteoblastic differentiation of marrow stromal cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 1997-2003. PMID 12412807 DOI: 10.1359/Jbmr.2002.17.11.1997  0.56
2002 Parhami F, Basseri B, Hwang J, Tintut Y, Demer LL. High-density lipoprotein regulates calcification of vascular cells. Circulation Research. 91: 570-6. PMID 12364384 DOI: 10.1161/01.Res.0000036607.05037.Da  0.56
2002 Demer LL. Vascular calcification and osteoporosis: inflammatory responses to oxidized lipids. International Journal of Epidemiology. 31: 737-41. PMID 12177011 DOI: 10.1093/Ije/31.4.737  0.56
2002 Hsiai TK, Cho SK, Honda HM, Hama S, Navab M, Demer LL, Ho CM. Endothelial cell dynamics under pulsating flows: significance of high versus low shear stress slew rates (d(tau)/dt). Annals of Biomedical Engineering. 30: 646-56. PMID 12108839 DOI: 10.1114/1.1484222  0.56
2002 Demer LL, Tintut Y, Parhami F. Novel mechanisms in accelerated vascular calcification in renal disease patients. Current Opinion in Nephrology and Hypertension. 11: 437-43. PMID 12105395 DOI: 10.1097/00041552-200207000-00011  0.56
2002 Demer LL. Adipose rex: fat and fats that rule differentiation. Circulation Research. 90: 241-3. PMID 11861408 DOI: 10.1161/Res.90.3.241  0.56
2002 Tintut Y, Parhami F, Tsingotjidou A, Tetradis S, Territo M, Demer LL. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway. The Journal of Biological Chemistry. 277: 14221-6. PMID 11827970 DOI: 10.1074/Jbc.M111551200  0.56
2002 Tintut Y, Patel J, Territo M, Saini T, Parhami F, Demer LL. Monocyte/macrophage regulation of vascular calcification in vitro. Circulation. 105: 650-5. PMID 11827934 DOI: 10.1161/Hc0502.102969  0.56
2002 Hsiai TK, Cho SK, Wong PK, Ing M, Navab M, Reddy S, Demer LL, Ho CM. Bio-MEMS sensors for real-time shear stress on endothelial cell dynamics Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 3: 1828-1829.  0.56
2001 Hsiai TK, Cho SK, Reddy S, Hama S, Navab M, Demer LL, Honda HM, Ho CM. Pulsatile flow regulates monocyte adhesion to oxidized lipid-induced endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1770-6. PMID 11701464 DOI: 10.1161/Hq1001.097104  0.56
2001 Demer LL. Cholesterol in vascular and valvular calcification Circulation. 104: 1881-1883. PMID 11602487 DOI: 10.1161/Circ.104.16.1881  0.56
2001 Demer LL. Boning up (or down) on statins Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1565-1566. PMID 11597926 DOI: 10.1161/Atvb.21.10.1565  0.56
2001 Honda HM, Hsiai T, Wortham CM, Chen M, Lin H, Navab M, Demer LL. A complex flow pattern of low shear stress and flow reversal promotes monocyte binding to endothelial cells Atherosclerosis. 158: 385-390. PMID 11583717 DOI: 10.1016/S0021-9150(01)00462-2  0.56
2001 Tintut Y, Demer LL. Recent advances in multifactorial regulation of vascular calcification Current Opinion in Lipidology. 12: 555-560. PMID 11561176 DOI: 10.1097/00041433-200110000-00012  0.56
2001 Mody N, Parhami F, Sarafian TA, Demer LL. Oxidative stress modulates osteoblastic differentiation of vascular and bone cells. Free Radical Biology & Medicine. 31: 509-19. PMID 11498284 DOI: 10.1016/S0891-5849(01)00610-4  0.56
2001 Poggi SH, Bostrom KI, Demer LL, Skinner HC, Koos BJ. Placental calcification: A metastatic process? Placenta. 22: 591-596. PMID 11440548 DOI: 10.1053/Plac.2001.0688  0.56
2001 Parhami F, Tintut Y, Patel JK, Mody N, Hemmat A, Demer LL. Regulation of vascular calcification in atherosclerosis. Zeitschrift FüR Kardiologie. 90: 27-30. PMID 11374029 DOI: 10.1007/S003920170038  0.56
2001 Parhami F, Tintut Y, Ballard A, Fogelman AM, Demer LL. Leptin enhances the calcification of vascular cells artery wall as a target of leptin Circulation Research. 88: 954-960. PMID 11349006 DOI: 10.1161/Hh0901.090975  0.56
2001 Boström K, Tsao D, Shen S, Wang Y, Demer LL. Matrix GLA protein modulates differentiation induced by bone morphogenetic protein-2 in C3H10T1/2 cells. The Journal of Biological Chemistry. 276: 14044-52. PMID 11278388 DOI: 10.1074/Jbc.M008103200  0.56
2001 Parhami F, Tintut Y, Beamer WG, Gharavi N, Goodman W, Demer LL. Atherogenic high-fat diet reduces bone mineralization in mice Journal of Bone and Mineral Research. 16: 182-188. PMID 11149483 DOI: 10.1359/Jbmr.2001.16.1.182  0.56
2000 Tintut Y, Patel J, Parhami F, Demer LL. Tumor necrosis factor-α promotes in vitro calcification of vascular cells via the cAMP pathway Circulation. 102: 2636-2642. PMID 11085968 DOI: 10.1161/01.Cir.102.21.2636  0.56
2000 Parhami F, Garfinkel A, Demer LL. Role of lipids in osteoporosis Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2346-2348. PMID 11073836 DOI: 10.1161/01.Atv.20.11.2346  0.56
2000 Boström K, Tintut Y, Kao SC, Stanford WP, Demer LL. HOXB7 overexpression promotes differentiation of C3H10T1/2 cells to smooth muscle cells Journal of Cellular Biochemistry. 78: 210-221. PMID 10842316 DOI: 10.1002/(Sici)1097-4644(20000801)78:2<210::Aid-Jcb4>3.0.Co;2-Z  0.56
2000 Jackson SM, Demer LL. Peroxisome proliferator-activated receptor activators modulate the osteoblastic maturation of MC3T3-E1 preosteoblasts. Febs Letters. 471: 119-24. PMID 10760525 DOI: 10.1016/S0014-5793(00)01372-7  0.56
2000 Law RE, Goetze S, Xi XP, Jackson S, Kawano Y, Demer L, Fishbein MC, Meehan WP, Hsueh WA. Expression and function of PPARγ in rat and human vascular smooth muscle cells Circulation. 101: 1311-1318. PMID 10725292 DOI: 10.1161/01.Cir.101.11.1311  0.56
2000 Port S, Demer L, Jennrich R, Walter D, Garfinkel A. Systolic blood pressure and mortality. Lancet (London, England). 355: 175-80. PMID 10675116 DOI: 10.1016/S0140-6736(99)07051-8  0.56
2000 Hsiai T, Cho S, Hama S, Linda J, Honda H, Demer L, Navab M, Ho CM. Pulsatile vs. oscillatory flow profiles induce opposite effects on monocyte adhesion to endothelialized glass surface Annals of Biomedical Engineering. 28: S-120.  0.56
1999 Parhami F, Jackson SM, Tintut Y, Le V, Balucan JP, Territo M, Demer LL. Atherogenic diet and minimally oxidized low density lipoprotein inhibit osteogenic and promote adipogenic differentiation of marrow stromal cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 14: 2067-78. PMID 10620066 DOI: 10.1359/Jbmr.1999.14.12.2067  0.56
1999 Tintut Y, Parhami F, Le V, Karsenty G, Demer LL. Inhibition of osteoblast-specific transcription factor Cbfa1 by the cAMP pathway in osteoblastic cells. Ubiquitin/proteasome-dependent regulation. Journal of Biological Chemistry. 274: 28875-28879. PMID 10506130 DOI: 10.1074/Jbc.274.41.28875  0.56
1999 Jackson SM, Parhami F, Xi XP, Berliner JA, Hsueh WA, Law RE, Demer LL. Peroxisome proliferator-activated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction. Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 2094-104. PMID 10479650 DOI: 10.1161/01.Atv.19.9.2094  0.56
1998 Tintut Y, Parhami F, Boström K, Jackson SM, Demer LL. cAMP stimulates osteoblast-like differentiation of calcifying vascular cells. Potential signaling pathway for vascular calcification. The Journal of Biological Chemistry. 273: 7547-53. PMID 9516456 DOI: 10.1074/Jbc.273.13.7547  0.56
1997 Parhami F, Morrow AD, Balucan J, Leitinger N, Watson AD, Tintut Y, Berliner JA, Demer LL. Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation: A possible explanation for the paradox of arterial calcification in osteoporotic patients Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 680-687. PMID 9108780 DOI: 10.1161/01.Atv.17.4.680  0.56
1996 Navab M, Berliner JA, Watson AD, Hama SY, Territo MC, Lusis AJ, Shih DM, Van Lenten BJ, Frank JS, Demer LL, Edwards PA, Fogelman AM. The Yin and Yang of oxidation in the development of the fatty streak. A review based on the 1994 George Lyman Duff Memorial Lecture. Arteriosclerosis, Thrombosis, and Vascular Biology. 16: 831-42. PMID 8673557 DOI: 10.1161/01.Atv.16.7.831  0.56
1996 Uyemura K, Demer LL, Castle SC, Jullien D, Berliner JA, Gately MK, Warrier RR, Pham N, Fogelman AM, Modlin RL. Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis. The Journal of Clinical Investigation. 97: 2130-8. PMID 8621803 DOI: 10.1172/Jci118650  0.56
1995 Berliner JA, Navab M, Fogelman AM, Frank JS, Demer LL, Edwards PA, Watson AD, Lusis AJ. Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics. Circulation. 91: 2488-96. PMID 7729036 DOI: 10.1161/01.Cir.91.9.2488  0.56
1995 Navab M, Fogelman AM, Berliner JA, Territo MC, Demer LL, Frank JS, Watson AD, Edwards PA, Lusis AJ. Pathogenesis of atherosclerosis. The American Journal of Cardiology. 76: 18C-23C. PMID 7572682 DOI: 10.1016/S0002-9149(99)80466-4  0.56
1995 Qiao JH, Fishbein MC, Demer LL, Lusis AJ. Genetic determination of cartilaginous metaplasia in mouse aorta Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 2265-2272. PMID 7489252 DOI: 10.1161/01.Atv.15.12.2265  0.56
1994 Chang GJ, Woo P, Honda HM, Ignarro LJ, Young L, Berliner JA, Demer LL. Oxidation of LDL to a biologically active form by derivatives of nitric oxide and nitrite in the absence of superoxide: Dependence on pH and oxygen Arteriosclerosis, Thrombosis, and Vascular Biology. 14: 1808-1814. PMID 7947607 DOI: 10.1161/01.Atv.14.11.1808  0.56
1993 Bennett RL, Navab M, Demer LL, Fogelman AM. A new anti-inflammatory leucine derivative, NPC-15669, inhibits growth of cultured human aortic smooth muscle cells. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 13: 360-6. PMID 8443139 DOI: 10.1161/01.Atv.13.3.360  0.56
1991 Mehrabian M, Demer LL, Lusis AJ. Differential accumulation of intimal monocyte-macrophages relative to lipoproteins and lipofuscin corresponds to hemodynamic forces on cardiac valves in mice Arteriosclerosis, Thrombosis, and Vascular Biology. 11: 947-957. PMID 2065045 DOI: 10.1161/01.Atv.11.4.947  0.56
1991 Liao F, Berliner JA, Mehrabian M, Navab M, Demer LL, Lusis AJ, Fogelman AM. Minimally modified low density lipoprotein Is biologically active in vivo in mice Journal of Clinical Investigation. 87: 2253-2257. PMID 2040705 DOI: 10.1172/Jci115261  0.56
1989 Demer LL, Gould KL, Goldstein RA, Kirkeeide RL, Mullani NA, Smalling RW, Nishikawa A, Merhige ME. Assessment of coronary artery disease severity by positron emission tomography. Comparison with quantitative arteriography in 193 patients. Circulation. 79: 825-35. PMID 2784361 DOI: 10.1161/01.Cir.79.4.825  0.56
1988 Demer L, Gould KL, Kirkeeide R. Assessing stenosis severity: Coronary flow reserve, collateral function, quantitative coronary arteriography, positron imaging, and digital subtraction angiography. A review and analysis Progress in Cardiovascular Diseases. 30: 307-322. PMID 3279459 DOI: 10.1016/0033-0620(88)90001-1  0.56
1987 Goldstein RA, Kirkeeide RL, Demer LL, Merhige M, Nishikawa A, Smalling RW, Mullani NA, Gould KL. Relation between geometric dimensions of coronary artery stenoses and myocardial perfusion reserve in man. The Journal of Clinical Investigation. 79: 1473-8. PMID 3494749 DOI: 10.1172/Jci112976  0.56
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