| Year |
Citation |
Score |
| 2020 |
Ruf-Zamojski FM, Zamojski MA, Nudelman G, Ge Y, Mendelev N, Smith GR, Zhou X, Toufaily C, Schang G, Gambino LO, Liu H, Gomez Castanon RG, Moriwaki M, Nair V, Pincas H, ... ... Sealfon SC, et al. SAT-298 Integrative Single-Cell Transcriptomic and Epigenomic Landscape of Mouse Anterior Pituitary Cell Types Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.593 |
0.354 |
|
| 2019 |
Monteagudo PL, Muñoz-Moreno R, Fribourg M, Potla U, Mena I, Marjanovic N, Hartmann BM, Sealfon SC, García-Sastre A, Ramos I, Fernández-Sesma A. Differential modulation of innate immune responses in human primary cells by influenza A viruses carrying human or avian non-structural 1 proteins. Journal of Virology. PMID 31597767 DOI: 10.1128/Jvi.00999-19 |
0.318 |
|
| 2019 |
Ramos I, Smith G, Ruf-Zamojski F, Martinez-Romero C, Fribourg M, Carbajal EA, Hartmann BM, Nair VD, Marjanovic N, Monteagudo PL, DeJesus VA, Mutetwa T, Zamojski M, Tan GS, Jayaprakash C, ... ... Sealfon SC, et al. Innate immune response to influenza virus at single-cell resolution in human epithelial cells revealed paracrine induction of interferon lambda 1. Journal of Virology. PMID 31375585 DOI: 10.1128/Jvi.00559-19 |
0.329 |
|
| 2019 |
Mao W, Zaslavsky E, Hartmann BM, Sealfon SC, Chikina M. Pathway-level information extractor (PLIER) for gene expression data. Nature Methods. 16: 607-610. PMID 31249421 DOI: 10.1038/S41592-019-0456-1 |
0.336 |
|
| 2019 |
Ruf-Zamojski F, Ge Y, Pincas H, Shan J, Song Y, Hines N, Kelley K, Montagna C, Nair P, Toufaily C, Bernard DJ, Mellon PL, Nair V, Turgeon JL, Sealfon SC. Cytogenetic, Genomic, and Functional Characterization of Pituitary Gonadotrope Cell Lines. Journal of the Endocrine Society. 3: 902-920. PMID 31020055 DOI: 10.1210/Js.2019-00064 |
0.306 |
|
| 2018 |
Ruf-Zamojski F, Ge Y, Nair V, Zamojski M, Pincas H, Toufaily C, Tome-Garcia J, Stoeckius M, Stephenson W, Smith GR, Bernard DJ, Tsankova NM, Hartmann BM, Fribourg M, Smibert P, ... ... Sealfon SC, et al. Single-cell stabilization method identifies gonadotrope transcriptional dynamics and pituitary cell type heterogeneity. Nucleic Acids Research. PMID 30357357 DOI: 10.1093/Nar/Gky991 |
0.37 |
|
| 2018 |
Ruf-Zamojski F, Fribourg M, Ge Y, Nair V, Pincas H, Zaslavsky E, Nudelman G, Tuminello SJ, Watanabe H, Turgeon JL, Sealfon SC. Regulatory Architecture of the LβT2 Gonadotrope Cell Underlying the Response to Gonadotropin-Releasing Hormone. Frontiers in Endocrinology. 9: 34. PMID 29487567 DOI: 10.3389/Fendo.2018.00034 |
0.366 |
|
| 2017 |
Stern E, Ruf-Zamojski F, Zalepa-King L, Pincas H, Choi SG, Peskin CS, Fernand H, Turgeon JL, Sealfon SC. Modeling and High-Throughput Experimental Data Uncover the Mechanisms Underlying Fshb Gene Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency. The Journal of Biological Chemistry. PMID 28385888 DOI: 10.1074/Jbc.M117.783886 |
0.321 |
|
| 2016 |
Choi SG, Wang Q, Jia J, Chikina M, Pincas H, Dolios G, Sasaki K, Wang R, Minamino N, Salton SR, Sealfon SC. Characterization of gonadotrope secretoproteome identifies neurosecretory protein VGF-derived peptide suppression of follicle-stimulating hormone gene expression. The Journal of Biological Chemistry. PMID 27466366 DOI: 10.1074/Jbc.M116.740365 |
0.368 |
|
| 2016 |
Nogusa S, Thapa RJ, Dillon CP, Liedmann S, Oguin TH, Ingram JP, Rodriguez DA, Kosoff R, Sharma S, Sturm O, Verbist K, Gough PJ, Bertin J, Hartmann BM, Sealfon SC, et al. RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus. Cell Host & Microbe. PMID 27321907 DOI: 10.1016/J.Chom.2016.05.011 |
0.329 |
|
| 2016 |
Baki L, Fribourg M, Younkin J, Eltit JM, Moreno JL, Park G, Vysotskaya Z, Narahari A, Sealfon SC, Gonzalez-Maeso J, Logothetis DE. Cross-signaling in metabotropic glutamate 2 and serotonin 2A receptor heteromers in mammalian cells. Pflugers Archiv : European Journal of Physiology. PMID 26780666 DOI: 10.1007/S00424-015-1780-7 |
0.386 |
|
| 2015 |
Thakar J, Hartmann BM, Marjanovic N, Sealfon SC, Kleinstein SH. Comparative analysis of anti-viral transcriptomics reveals novel effects of influenza immune antagonism. Bmc Immunology. 16: 46. PMID 26272204 DOI: 10.1186/S12865-015-0107-Y |
0.317 |
|
| 2015 |
Patil S, Fribourg M, Ge Y, Batish M, Tyagi S, Hayot F, Sealfon SC. Single-cell analysis shows that paracrine signaling by first responder cells shapes the interferon-β response to viral infection. Science Signaling. 8: ra16. PMID 25670204 DOI: 10.1126/Scisignal.2005728 |
0.37 |
|
| 2015 |
Chikina M, Zaslavsky E, Sealfon SC. CellCODE: a robust latent variable approach to differential expression analysis for heterogeneous cell populations. Bioinformatics (Oxford, England). 31: 1584-91. PMID 25583121 DOI: 10.1093/Bioinformatics/Btv015 |
0.318 |
|
| 2014 |
Choi SG, Wang Q, Jia J, Pincas H, Turgeon JL, Sealfon SC. Growth differentiation factor 9 (GDF9) forms an incoherent feed-forward loop modulating follicle-stimulating hormone β-subunit (FSHβ) gene expression. The Journal of Biological Chemistry. 289: 16164-75. PMID 24778184 DOI: 10.1074/Jbc.M113.537696 |
0.378 |
|
| 2014 |
Hartmann BM, Marjanovic N, Nudelman G, Moran TM, Sealfon SC. Combinatorial cytokine code generates anti-viral state in dendritic cells. Frontiers in Immunology. 5: 73. PMID 24616721 DOI: 10.3389/Fimmu.2014.00073 |
0.346 |
|
| 2014 |
Wang Q, Chikina MD, Pincas H, Sealfon SC. Homer1 alternative splicing is regulated by gonadotropin-releasing hormone and modulates gonadotropin gene expression. Molecular and Cellular Biology. 34: 1747-56. PMID 24591653 DOI: 10.1128/Mcb.01401-13 |
0.361 |
|
| 2014 |
Pincas H, Choi SG, Wang Q, Jia J, Turgeon JL, Sealfon SC. Outside the box signaling: secreted factors modulate GnRH receptor-mediated gonadotropin regulation. Molecular and Cellular Endocrinology. 385: 56-61. PMID 23994024 DOI: 10.1016/J.Mce.2013.08.015 |
0.41 |
|
| 2013 |
Tabbaa OP, Nudelman G, Sealfon SC, Hayot F, Jayaprakash C. Noise propagation through extracellular signaling leads to fluctuations in gene expression. Bmc Systems Biology. 7: 94. PMID 24067165 DOI: 10.1186/1752-0509-7-94 |
0.367 |
|
| 2013 |
Moreno JL, Holloway T, Rayannavar V, Sealfon SC, González-Maeso J. Chronic treatment with LY341495 decreases 5-HT(2A) receptor binding and hallucinogenic effects of LSD in mice. Neuroscience Letters. 536: 69-73. PMID 23333599 DOI: 10.1016/J.Neulet.2012.12.053 |
0.314 |
|
| 2013 |
Braun DA, Fribourg M, Sealfon SC. Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activation. The Journal of Biological Chemistry. 288: 2986-93. PMID 23166328 DOI: 10.1074/Jbc.M112.386573 |
0.523 |
|
| 2013 |
Baki L, Eltit JM, Fribourg M, Younkin J, Park G, Vysotskaya Z, Sealfon SC, Liapakis G, Gonzalez-Maeso J, Logothetis DE. Functional Crosstalk between mGluR2 and 5-HT2A Depends on their Expression Ratios Biophysical Journal. 104: 116a. DOI: 10.1016/J.Bpj.2012.11.671 |
0.389 |
|
| 2013 |
Tabbaa OP, Nudelman G, Sealfon SC, Jayaprakash C. Noise Propagation through Cytokine Signaling Leads to Fluctuations in Interferon-Induced Genes Biophysical Journal. 104: 493a. DOI: 10.1016/J.Bpj.2012.11.2719 |
0.363 |
|
| 2012 |
Moreno JL, Muguruza C, Umali A, Mortillo S, Holloway T, Pilar-Cuéllar F, Mocci G, Seto J, Callado LF, Neve RL, Milligan G, Sealfon SC, López-Giménez JF, Meana JJ, Benson DL, et al. Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A·mGlu2) receptor heteromerization and its psychoactive behavioral function. The Journal of Biological Chemistry. 287: 44301-19. PMID 23129762 DOI: 10.1074/Jbc.M112.413161 |
0.331 |
|
| 2012 |
Nair VD, Ge Y, Balasubramaniyan N, Kim J, Okawa Y, Chikina M, Troyanskaya O, Sealfon SC. Involvement of histone demethylase LSD1 in short-time-scale gene expression changes during cell cycle progression in embryonic stem cells. Molecular and Cellular Biology. 32: 4861-76. PMID 23028048 DOI: 10.1128/Mcb.00816-12 |
0.333 |
|
| 2012 |
González-Maeso J, Sealfon SC. Functional selectivity in GPCR heterocomplexes. Mini Reviews in Medicinal Chemistry. 12: 851-5. PMID 22681249 DOI: 10.2174/138955712800959152 |
0.349 |
|
| 2012 |
Choi SG, Jia J, Pfeffer RL, Sealfon SC. G proteins and autocrine signaling differentially regulate gonadotropin subunit expression in pituitary gonadotrope. The Journal of Biological Chemistry. 287: 21550-60. PMID 22549790 DOI: 10.1074/Jbc.M112.348607 |
0.368 |
|
| 2012 |
Yuen T, Choi SG, Pincas H, Waring DW, Sealfon SC, Turgeon JL. Optimized amplification and single-cell analysis identify GnRH-mediated activation of Rap1b in primary rat gonadotropes. Molecular and Cellular Endocrinology. 350: 10-9. PMID 22127306 DOI: 10.1016/J.Mce.2011.11.017 |
0.379 |
|
| 2011 |
Shimoni Y, Nudelman G, Hayot F, Sealfon SC. Multi-scale stochastic simulation of diffusion-coupled agents and its application to cell culture simulation. Plos One. 6: e29298. PMID 22216238 DOI: 10.1371/Journal.Pone.0029298 |
0.301 |
|
| 2011 |
Fribourg M, Moreno JL, Holloway T, Provasi D, Baki L, Mahajan R, Park G, Adney SK, Hatcher C, Eltit JM, Ruta JD, Albizu L, Li Z, Umali A, Shim J, ... ... Sealfon SC, et al. Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs. Cell. 147: 1011-23. PMID 22118459 DOI: 10.1016/J.Cell.2011.09.055 |
0.325 |
|
| 2011 |
Bowles R, Patil S, Pincas H, Sealfon SC. Optimized protocol for efficient transfection of dendritic cells without cell maturation. Journal of Visualized Experiments : Jove. e2766. PMID 21775957 DOI: 10.3791/2766 |
0.342 |
|
| 2011 |
Choi SG, Ruf-Zamojski F, Pincas H, Roysam B, Sealfon SC. Characterization of a MAPK scaffolding protein logic gate in gonadotropes. Molecular Endocrinology (Baltimore, Md.). 25: 1027-39. PMID 21436256 DOI: 10.1210/Me.2010-0387 |
0.364 |
|
| 2011 |
Hu J, Nudelman G, Shimoni Y, Kumar M, Ding Y, López C, Hayot F, Wetmur JG, Sealfon SC. Role of cell-to-cell variability in activating a positive feedback antiviral response in human dendritic cells. Plos One. 6: e16614. PMID 21347441 DOI: 10.1371/Journal.Pone.0016614 |
0.365 |
|
| 2011 |
Moreno JL, Holloway T, Albizu L, Sealfon SC, González-Maeso J. Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists. Neuroscience Letters. 493: 76-9. PMID 21276828 DOI: 10.1016/J.Neulet.2011.01.046 |
0.322 |
|
| 2011 |
Sealfon SC. Synthesis, Internalization, Recycling, and Regulation of Peptide Hormone Receptors Comprehensive Physiology. 23-38. DOI: 10.1002/Cphy.Cp070102 |
0.341 |
|
| 2010 |
Patil S, Pincas H, Seto J, Nudelman G, Nudelman I, Sealfon SC. Signaling network of dendritic cells in response to pathogens: a community-input supported knowledgebase. Bmc Systems Biology. 4: 137. PMID 20929569 DOI: 10.1186/1752-0509-4-137 |
0.316 |
|
| 2010 |
Bowles R, Patil S, Pincas H, Sealfon SC. Validation of efficient high-throughput plasmid and siRNA transfection of human monocyte-derived dendritic cells without cell maturation. Journal of Immunological Methods. 363: 21-8. PMID 20875421 DOI: 10.1016/J.Jim.2010.09.028 |
0.355 |
|
| 2010 |
Seto J, Qiao L, Guenzel CA, Xiao S, Shaw ML, Hayot F, Sealfon SC. Novel Nipah virus immune-antagonism strategy revealed by experimental and computational study. Journal of Virology. 84: 10965-73. PMID 20739535 DOI: 10.1128/Jvi.01335-10 |
0.32 |
|
| 2010 |
Albizu L, Moreno JL, González-Maeso J, Sealfon SC. Heteromerization of G protein-coupled receptors: relevance to neurological disorders and neurotherapeutics. Cns & Neurological Disorders Drug Targets. 9: 636-50. PMID 20632964 DOI: 10.2174/187152710793361586 |
0.352 |
|
| 2010 |
Fink MY, Pincas H, Choi SG, Nudelman G, Sealfon SC. Research resource: Gonadotropin-releasing hormone receptor-mediated signaling network in LbetaT2 cells: a pathway-based web-accessible knowledgebase. Molecular Endocrinology (Baltimore, Md.). 24: 1863-71. PMID 20592162 DOI: 10.1210/Me.2009-0530 |
0.375 |
|
| 2010 |
Shimoni Y, Fink MY, Choi SG, Sealfon SC. Plato's cave algorithm: inferring functional signaling networks from early gene expression shadows. Plos Computational Biology. 6: e1000828. PMID 20585619 DOI: 10.1371/Journal.Pcbi.1000828 |
0.313 |
|
| 2010 |
Nudelman G, Ge Y, Hu J, Kumar M, Seto J, Duke JL, Kleinstein SH, Hayot F, Sealfon SC, Wetmur JG. Coregulation mapping based on individual phenotypic variation in response to virus infection. Immunome Research. 6: 2. PMID 20298589 DOI: 10.1186/1745-7580-6-2 |
0.303 |
|
| 2010 |
Zaslavsky E, Hershberg U, Seto J, Pham AM, Marquez S, Duke JL, Wetmur JG, Tenoever BR, Sealfon SC, Kleinstein SH. Antiviral response dictated by choreographed cascade of transcription factors. Journal of Immunology (Baltimore, Md. : 1950). 184: 2908-17. PMID 20164420 DOI: 10.4049/Jimmunol.0903453 |
0.347 |
|
| 2010 |
Qiao L, Phipps-Yonas H, Hartmann B, Moran TM, Sealfon SC, Hayot F. Immune response modeling of interferon beta-pretreated influenza virus-infected human dendritic cells. Biophysical Journal. 98: 505-14. PMID 20159146 DOI: 10.1016/J.Bpj.2009.10.049 |
0.323 |
|
| 2009 |
Hu J, Iyer-Biswas S, Sealfon SC, Wetmur J, Jayaprakash C, Hayot F. Power-laws in interferon-B mRNA distribution in virus-infected dendritic cells. Biophysical Journal. 97: 1984-9. PMID 19804729 DOI: 10.1016/J.Bpj.2009.05.067 |
0.347 |
|
| 2009 |
González-Maeso J, Sealfon SC. Agonist-trafficking and hallucinogens. Current Medicinal Chemistry. 16: 1017-27. PMID 19275609 DOI: 10.2174/092986709787581851 |
0.371 |
|
| 2009 |
Biswas SI, Hayot F, Jayaprakash C, Hu J, Wetmur J, Sealfon S. A Powerful Response to Viral Infection Biophysical Journal. 96: 567a. DOI: 10.1016/J.Bpj.2008.12.3718 |
0.317 |
|
| 2009 |
Fribourg-Casajuana M, González-Maeso J, Sealfon SC, Logothetis DE. Functional Evidence for Gi-Gq crosstalk through G protein-coupled Receptor Heterocomplexes Biophysical Journal. 96: 674a-675a. DOI: 10.1016/J.Bpj.2008.12.3565 |
0.382 |
|
| 2008 |
Phipps-Yonas H, Seto J, Sealfon SC, Moran TM, Fernandez-Sesma A. Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus. Plos Pathogens. 4: e1000193. PMID 18974865 DOI: 10.1371/Journal.Ppat.1000193 |
0.303 |
|
| 2008 |
Phipps-Yonas H, Jiang K, Hartmann BM, Ge Y, Sealfon SC, Moran TM. A comprehensive evaluation of human plasmacytoid dendritic cells using small volumes of human blood. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 28: 501-7. PMID 18729740 DOI: 10.1089/Jir.2008.0014 |
0.308 |
|
| 2008 |
Sealfon SC, González-Maeso J. Receptor pair for schizophrenia. Pediatric Research. 64: 1. PMID 18574404 DOI: 10.1203/Pdr.0B013E318180052A |
0.325 |
|
| 2008 |
Berezhkovskii AM, Coppey M, Sealfon SC, Shvartsman S. Cell-to-cell communication: time and length scales of ligand internalization in cultures of suspended cells. The Journal of Chemical Physics. 128: 225102. PMID 18554059 DOI: 10.1063/1.2936845 |
0.324 |
|
| 2008 |
Viswanathan GA, Seto J, Patil S, Nudelman G, Sealfon SC. Getting started in biological pathway construction and analysis. Plos Computational Biology. 4: e16. PMID 18463709 DOI: 10.1371/Journal.Pcbi.0040016 |
0.308 |
|
| 2008 |
Arsov I, Li X, Matthews G, Coradin J, Hartmann B, Simon AK, Sealfon SC, Yue Z. BAC-mediated transgenic expression of fluorescent autophagic protein Beclin 1 reveals a role for Beclin 1 in lymphocyte development. Cell Death and Differentiation. 15: 1385-95. PMID 18451870 DOI: 10.1038/Cdd.2008.59 |
0.306 |
|
| 2008 |
González-Maeso J, Ang RL, Yuen T, Chan P, Weisstaub NV, López-Giménez JF, Zhou M, Okawa Y, Callado LF, Milligan G, Gingrich JA, Filizola M, Meana JJ, Sealfon SC. Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature. 452: 93-7. PMID 18297054 DOI: 10.1038/Nature06612 |
0.313 |
|
| 2007 |
Ruf F, Hayot F, Park MJ, Ge Y, Lin G, Roysam B, Sealfon SC. Noise propagation and scaling in regulation of gonadotrope biosynthesis. Biophysical Journal. 93: 4474-80. PMID 17720728 DOI: 10.1529/Biophysj.107.115170 |
0.662 |
|
| 2007 |
Hu J, Sealfon SC, Hayot F, Jayaprakash C, Kumar M, Pendleton AC, Ganee A, Fernandez-Sesma A, Moran TM, Wetmur JG. Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells. Nucleic Acids Research. 35: 5232-41. PMID 17675303 DOI: 10.1093/Nar/Gkm557 |
0.332 |
|
| 2007 |
Lee KB, Khivansara V, Santos MM, Lamba P, Yuen T, Sealfon SC, Bernard DJ. Bone morphogenetic protein 2 and activin A synergistically stimulate follicle-stimulating hormone beta subunit transcription. Journal of Molecular Endocrinology. 38: 315-30. PMID 17293449 DOI: 10.1677/Jme.1.02196 |
0.398 |
|
| 2007 |
González-Maeso J, Weisstaub NV, Zhou M, Chan P, Ivic L, Ang R, Lira A, Bradley-Moore M, Ge Y, Zhou Q, Sealfon SC, Gingrich JA. Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior. Neuron. 53: 439-52. PMID 17270739 DOI: 10.1016/J.Neuron.2007.01.008 |
0.343 |
|
| 2006 |
Ruf F, Park MJ, Hayot F, Lin G, Roysam B, Ge Y, Sealfon SC. Mixed analog/digital gonadotrope biosynthetic response to gonadotropin-releasing hormone. The Journal of Biological Chemistry. 281: 30967-78. PMID 16916798 DOI: 10.1074/Jbc.M606486200 |
0.656 |
|
| 2006 |
Grisotto MG, Garin A, Martin AP, Jensen KK, Chan P, Sealfon SC, Lira SA. The human herpesvirus 8 chemokine receptor vGPCR triggers autonomous proliferation of endothelial cells. The Journal of Clinical Investigation. 116: 1264-73. PMID 16604194 DOI: 10.1172/Jci26666 |
0.355 |
|
| 2005 |
Xie J, Bliss SP, Nett TM, Ebersole BJ, Sealfon SC, Roberson MS. Transcript profiling of immediate early genes reveals a unique role for activating transcription factor 3 in mediating activation of the glycoprotein hormone alpha-subunit promoter by gonadotropin-releasing hormone. Molecular Endocrinology (Baltimore, Md.). 19: 2624-38. PMID 15961508 DOI: 10.1210/Me.2005-0056 |
0.36 |
|
| 2005 |
Sealfon SC. Teaching resources. G-protein-coupled receptors. Science's Stke : Signal Transduction Knowledge Environment. 2005: tr11. PMID 15827322 DOI: 10.1126/Stke.2792005Tr11 |
0.326 |
|
| 2005 |
Omari KM, John GR, Sealfon SC, Raine CS. CXC chemokine receptors on human oligodendrocytes: implications for multiple sclerosis. Brain : a Journal of Neurology. 128: 1003-15. PMID 15774504 DOI: 10.1093/Brain/Awh479 |
0.311 |
|
| 2004 |
Ruf F, Sealfon SC. Genomics view of gonadotrope signaling circuits. Trends in Endocrinology and Metabolism: Tem. 15: 331-8. PMID 15350605 DOI: 10.1016/J.Tem.2004.07.008 |
0.373 |
|
| 2004 |
Mobbs CV, Yen K, Mastaitis J, Nguyen H, Watson E, Wurmbach E, Sealfon SC, Brooks A, Salton SR. Mining microarrays for metabolic meaning: nutritional regulation of hypothalamic gene expression. Neurochemical Research. 29: 1093-103. PMID 15176466 DOI: 10.1023/B:Nere.0000023596.49140.E0 |
0.315 |
|
| 2003 |
Ruf F, Fink MY, Sealfon SC. Structure of the GnRH receptor-stimulated signaling network: insights from genomics. Frontiers in Neuroendocrinology. 24: 181-99. PMID 14596811 DOI: 10.1016/S0091-3022(03)00027-X |
0.373 |
|
| 2003 |
Nair VD, Sealfon SC. Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor. The Journal of Biological Chemistry. 278: 47053-61. PMID 12970364 DOI: 10.1074/Jbc.M303364200 |
0.341 |
|
| 2003 |
Nair VD, Olanow CW, Sealfon SC. Activation of phosphoinositide 3-kinase by D2 receptor prevents apoptosis in dopaminergic cell lines. The Biochemical Journal. 373: 25-32. PMID 12683952 DOI: 10.1042/Bj20030017 |
0.376 |
|
| 2003 |
Ebersole BJ, Visiers I, Weinstein H, Sealfon SC. Molecular basis of partial agonism: orientation of indoleamine ligands in the binding pocket of the human serotonin 5-HT2A receptor determines relative efficacy. Molecular Pharmacology. 63: 36-43. PMID 12488534 DOI: 10.1124/Mol.63.1.36 |
0.336 |
|
| 2003 |
González-Maeso J, Yuen T, Ebersole BJ, Wurmbach E, Lira A, Zhou M, Weisstaub N, Hen R, Gingrich JA, Sealfon SC. Transcriptome Fingerprints Distinguish Hallucinogenic and Nonhallucinogenic 5-Hydroxytryptamine 2A Receptor Agonist Effects in Mouse Somatosensory Cortex The Journal of Neuroscience. 23: 8836-8843. DOI: 10.1523/Jneurosci.23-26-08836.2003 |
0.393 |
|
| 2002 |
Wurmbach E, González-Maeso J, Yuen T, Ebersole BJ, Mastaitis JW, Mobbs CV, Sealfon SC. Validated genomic approach to study differentially expressed genes in complex tissues. Neurochemical Research. 27: 1027-33. PMID 12462402 DOI: 10.1023/A:1020900720328 |
0.347 |
|
| 2002 |
Prioleau C, Visiers I, Ebersole BJ, Weinstein H, Sealfon SC. Conserved helix 7 tyrosine acts as a multistate conformational switch in the 5HT2C receptor. Identification of a novel "locked-on" phenotype and double revertant mutations. The Journal of Biological Chemistry. 277: 36577-84. PMID 12145300 DOI: 10.1074/Jbc.M206223200 |
0.358 |
|
| 2002 |
Yuen T, Wurmbach E, Ebersole BJ, Ruf F, Pfeffer RL, Sealfon SC. Coupling of GnRH concentration and the GnRH receptor-activated gene program. Molecular Endocrinology (Baltimore, Md.). 16: 1145-53. PMID 12040003 DOI: 10.1210/Mend.16.6.0853 |
0.368 |
|
| 2002 |
Yuen T, Zhang W, Ebersole BJ, Sealfon SC. Monitoring G-protein-coupled receptor signaling with DNA microarrays and real-time polymerase chain reaction. Methods in Enzymology. 345: 556-69. PMID 11665639 DOI: 10.1016/S0076-6879(02)45047-1 |
0.405 |
|
| 2002 |
Ebersole BJ, Sealfon SC. Strategies for mapping the binding site of the serotonin 5-HT2A receptor. Methods in Enzymology. 343: 123-36. PMID 11665561 DOI: 10.1016/S0076-6879(02)43130-8 |
0.338 |
|
| 2002 |
KRAKAUER DC, PAGE KM, SEALFON S. Module Dynamics of the GnRH Signal Transduction Network Journal of Theoretical Biology. 218: 457-470. DOI: 10.1006/Jtbi.2002.3092 |
0.321 |
|
| 2002 |
Visiers I, Ebersole BJ, Dracheva S, Ballesteros J, Sealfon SC, Weinstein H. Structural motifs as functional microdomains in G-protein-coupled receptors: Energetic considerations in the mechanism of activation of the serotonin 5-HT2A receptor by disruption of the ionic lock of the arginine cage International Journal of Quantum Chemistry. 88: 65-75. DOI: 10.1002/Qua.10078 |
0.355 |
|
| 2001 |
Wurmbach E, Yuen T, Ebersole BJ, Sealfon SC. Gonadotropin-releasing Hormone Receptor-coupled Gene Network Organization Journal of Biological Chemistry. 276: 47195-47201. PMID 11581274 DOI: 10.1074/Jbc.M108716200 |
0.367 |
|
| 2001 |
Sealfon SC. Polymorphisms 'r us Clinical Autonomic Research. 11: 59-60. PMID 11570602 DOI: 10.1007/Bf02322045 |
0.328 |
|
| 2001 |
Kitanovic S, Yuen T, Flanagan CA, Ebersole BJ, Sealfon SC. Insertional mutagenesis of the arginine cage domain of the gonadotropin-releasing hormone receptor. Molecular Endocrinology (Baltimore, Md.). 15: 390-7. PMID 11222740 DOI: 10.1210/Mend.15.3.0611 |
0.346 |
|
| 2001 |
Sun YM, Flanagan CA, Illing N, Ott TR, Sellar R, Fromme BJ, Hapgood J, Sharp P, Sealfon SC, Millar RP. A chicken gonadotropin-releasing hormone receptor that confers agonist activity to mammalian antagonists. Identification of D-Lys(6) in the ligand and extracellular loop two of the receptor as determinants. The Journal of Biological Chemistry. 276: 7754-61. PMID 11112780 DOI: 10.1074/Jbc.M009020200 |
0.376 |
|
| 2000 |
Rosendorff A, Ebersole BJ, Sealfon SC. Conserved helix 7 tyrosine functions as an activation relay in the serotonin 5HT(2C) receptor Molecular Brain Research. 84: 90-96. PMID 11113535 DOI: 10.1016/S0169-328X(00)00227-8 |
0.354 |
|
| 2000 |
Sealfon SC, Olanow CW. Dopamine receptors: From structure to behavior Trends in Neurosciences. 23: S34-S40. PMID 11052218 DOI: 10.1016/S1471-1931(00)00025-2 |
0.397 |
|
| 2000 |
Flanagan CA, Rodic V, Konvicka K, Yuen T, Chi L, Rivier JE, Millar RP, Weinstein H, Sealfon SC. Multiple interactions of the Asp(2.61(98)) side chain of the gonadotropin-releasing hormone receptor contribute differentially to ligand interaction. Biochemistry. 39: 8133-41. PMID 10889019 DOI: 10.1021/Bi000085G |
0.315 |
|
| 2000 |
Klein C, Gurvich N, Sena-Esteves M, Bressman S, Brin MF, Ebersole BJ, Fink S, Forsgren L, Friedman J, Grimes D, Holmgren G, Kyllerman M, Lang AE, de Leon D, Leung J, ... ... Sealfon SC, et al. Evaluation of the role of the D2 dopamine receptor in myoclonus dystonia. Annals of Neurology. 47: 369-73. PMID 10716258 DOI: 10.1002/1531-8249(200003)47:3<369::Aid-Ana14>3.0.Co;2-9 |
0.313 |
|
| 1999 |
Flanagan CA, Zhou W, Chi L, Yuen T, Rodic V, Robertson D, Johnson M, Holland P, Millar RP, Weinstein H, Mitchell R, Sealfon SC. The functional microdomain in transmembrane helices 2 and 7 regulates expression, activation, and coupling pathways of the gonadotropin-releasing hormone receptor. The Journal of Biological Chemistry. 274: 28880-6. PMID 10506131 DOI: 10.1074/Jbc.274.41.28880 |
0.381 |
|
| 1999 |
Millar R, Conklin D, Lofton-Day C, Hutchinson E, Troskie B, Illing N, Sealfon SC, Hapgood J. A novel human GnRH receptor homolog gene: Abundant and wide tissue distribution of the antisense transcript Journal of Endocrinology. 162: 117-126. PMID 10396028 DOI: 10.1677/Joe.0.1620117 |
0.381 |
|
| 1999 |
Dracheva S, Xu M, Kelley KA, Haroutunian V, Holstein GR, Haun S, Silverstein JH, Sealfon SC. Paradoxical locomotor behavior of dopamine D1 receptor transgenic mice. Experimental Neurology. 157: 169-79. PMID 10222120 DOI: 10.1006/Exnr.1999.7037 |
0.322 |
|
| 1998 |
Ballesteros J, Kitanovic S, Guarnieri F, Davies P, Fromme BJ, Konvicka K, Chi L, Millar RP, Davidson JS, Weinstein H, Sealfon SC. Functional microdomains in G-protein-coupled receptors: The conserved arginine-cage motif in the gonadotropin-releasing hormone receptor Journal of Biological Chemistry. 273: 10445-10453. PMID 9553103 DOI: 10.1074/Jbc.273.17.10445 |
0.369 |
|
| 1998 |
Mitchell R, McCulloch D, Lutz E, Johnson M, MacKenzie C, Fennell M, Fink G, Zhou W, Sealfon SC. Rhodopsin-family receptors associate with small G proteins to activate phospholipase D Nature. 392: 411-414. PMID 9537328 DOI: 10.1038/32937 |
0.367 |
|
| 1997 |
Sealfon SC, Weinstein H, Millar RP. Molecular mechanisms of ligand interaction with the gonadotropin- releasing hormone receptor Endocrine Reviews. 18: 180-205. PMID 9101136 DOI: 10.1210/Edrv.18.2.0295 |
0.34 |
|
| 1996 |
Almaula N, Ebersole BJ, Zhang D, Weinstein H, Sealfon SC. Mapping the binding site pocket of the serotonin 5-hydroxytryptamine2A receptor: Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin Journal of Biological Chemistry. 271: 14672-14675. PMID 8663249 DOI: 10.1074/Jbc.271.25.14672 |
0.323 |
|
| 1996 |
Sealfon SC, Zhou W, Almaula N, Rodic V. [12] Cloning and site-directed mutagenesis studies of gonadotropin-releasing hormone receptor Methods in Neurosciences. 29: 143-169. DOI: 10.1016/S1043-9471(96)80048-6 |
0.371 |
|
| 1995 |
Sealfon SC, Millar RP. The gonadotrophin-releasing hormone receptor: Structural determinants and regulatory control Human Reproduction Update. 1: 216-230. PMID 9187940 DOI: 10.1093/Humupd/1.3.216 |
0.325 |
|
| 1995 |
Tsutsumi M, Laws SC, Rodic V, Sealfon SC. Translational regulation of the gonadotropin-releasing hormone receptor in αT3-1 cells Endocrinology. 136: 1128-1136. PMID 7867566 DOI: 10.1210/Endo.136.3.7867566 |
0.398 |
|
| 1995 |
Davidson JS, Flanagan CA, Zhou W, Becker II, Elario R, Emeran W, Sealfon SC, Millar RP. Identification of N-glycosylation sites in the gonadotropin-releasing hormone receptor: role in receptor expression but not ligand binding. Molecular and Cellular Endocrinology. 107: 241-5. PMID 7768336 DOI: 10.1016/0303-7207(94)03449-4 |
0.374 |
|
| 1995 |
Sealfon SC, Millar RP. Functional domains of the gonadotropin-releasing hormone receptor Cellular and Molecular Neurobiology. 15: 25-42. PMID 7648608 DOI: 10.1007/Bf02069557 |
0.362 |
|
| 1995 |
Zhou W, Rodic V, Kitanovic S, Flanagan CA, Chi L, Weinstein H, Maayani S, Millar RP, Sealfon SC. A locus of the gonadotropin-releasing hormone receptor that differentiates agonist and antagonist binding sites. The Journal of Biological Chemistry. 270: 18853-7. PMID 7642539 DOI: 10.1074/Jbc.270.32.18853 |
0.353 |
|
| 1995 |
Sealfon SC, Chi L, Ebersole BJ, Rodic V, Zhang D, Ballesteros JA, Weinstein H. Related contribution of specific helix 2 and 7 residues to conformational activation of the serotonin 5-HT2A receptor Journal of Biological Chemistry. 270: 16683-16688. PMID 7622478 DOI: 10.1074/Jbc.270.28.16683 |
0.343 |
|
| 1995 |
Sealfon SC. [1] Approaches to receptor cloning Methods in Neurosciences. 25: 3-8. DOI: 10.1016/S1043-9471(05)80031-X |
0.342 |
|
| 1994 |
Wu JC, Sealfon SC, Miller WL. Gonadal hormones and gonadotropin-releasing hormone (GnRH) alter messenger ribonucleic acid levels for GnRH receptors in sheep Endocrinology. 134: 1846-1850. PMID 8137751 DOI: 10.1210/Endo.134.4.8137751 |
0.307 |
|
| 1994 |
Davidson JS, Flanagan CA, Becker II, Illing N, Sealfon SC, Millar RP. Molecular function of the gonadotropin-releasing hormone receptor: insights from site-directed mutagenesis. Molecular and Cellular Endocrinology. 100: 9-14. PMID 8056165 DOI: 10.1016/0303-7207(94)90271-2 |
0.322 |
|
| 1994 |
Zhou W, Sealfon SC. Structure of the mouse gonadotropin-releasing hormone receptor gene: Variant transcripts generated by alternative processing Dna and Cell Biology. 13: 605-614. PMID 8024703 DOI: 10.1089/Dna.1994.13.605 |
0.376 |
|
| 1993 |
Chi L, Zhou W, Prikhozhan A, Flanagan C, Davidson JS, Golembo M, Illing N, Millar RP, Sealfon SC. Cloning and characterization of the human GnRH receptor Molecular and Cellular Endocrinology. 91: R1-R6. PMID 8386108 DOI: 10.1016/0303-7207(93)90278-R |
0.391 |
|
| 1993 |
Tsutsumi M, Laws SC, Sealfon SC. Homologous up-regulation of the gonadotropin-releasing hormone receptor in αT3-1 cells is associated with unchanged receptor messenger RNA (mRNA) levels and altered mRNA activity Molecular Endocrinology. 7: 1625-1633. PMID 8145768 DOI: 10.1210/Mend.7.12.8145768 |
0.411 |
|
| 1993 |
Illing N, Jacobs GF, Becker II, Flanagan CA, Davidson JS, Eales A, Zhou W, Sealfon SC, Millar RP. Comparative sequence analysis and functional characterization of the cloned sheep gonadotropin-releasing hormone receptor reveal differences in primary structure and ligand specificity among mammalian receptors. Biochemical and Biophysical Research Communications. 196: 745-51. PMID 7694577 DOI: 10.1006/Bbrc.1993.2312 |
0.39 |
|
| 1992 |
Huntley GW, Morrison JH, Prikhozhan A, Sealfon SC. Localization of multiple dopamine receptor subtype mRNAs in human and monkey motor cortex and striatum. Brain Research. Molecular Brain Research. 15: 181-8. PMID 1331674 DOI: 10.1016/0169-328X(92)90107-M |
0.311 |
|
| 1992 |
Tsutsumi M, Zhou W, Millar RP, Mellon PL, Roberts JL, Flanagan CA, Dong K, Gillo B, Sealfon SC. Cloning and functional expression of a mouse gonadotropin-releasing hormone receptor. Molecular Endocrinology (Baltimore, Md.). 6: 1163-9. PMID 1324422 DOI: 10.1210/Mend.6.7.1324422 |
0.409 |
|
| 1992 |
Probst WC, Snyder LA, Schuster DI, Brosius J, Sealfon SC. Sequence alignment of the G-protein coupled receptor superfamily. Dna and Cell Biology. 11: 1-20. PMID 1310857 DOI: 10.1089/Dna.1992.11.1 |
0.331 |
|
| 1991 |
Snyder LA, Roberts JL, Sealfon SC. Alternative transcripts of the rat and human dopamine D3 receptor. Biochemical and Biophysical Research Communications. 180: 1031-5. PMID 1953708 DOI: 10.1016/S0006-291X(05)81169-6 |
0.327 |
|
| 1991 |
McChesney R, Sealfon SC, Tsutsumi M, Dong KW, Roberts JL, Bancroft C. Either isoform of the dopamine D2 receptor can mediate dopaminergic repression of the rat prolactin promoter. Molecular and Cellular Endocrinology. 79: R1-7. PMID 1834494 DOI: 10.1016/0303-7207(91)90110-E |
0.375 |
|
| 1990 |
Sealfon SC, Gillo B, Mundamattom S, Mellon PL, Windle JJ, Landau E, Roberts JL. Gonadotropin-releasing hormone receptor expression in Xenopus oocytes. Molecular Endocrinology (Baltimore, Md.). 4: 119-24. PMID 2157973 DOI: 10.1210/Mend-4-1-119 |
0.32 |
|
| 1990 |
Sealfon SC, Laws SC, Wu JC, Gillo B, Miller WL. Hormonal regulation of gonadotropin-releasing hormone receptors and messenger RNA activity in ovine pituitary culture Molecular Endocrinology. 4: 1980-1987. PMID 1964491 DOI: 10.1210/Mend-4-12-1980 |
0.38 |
|
| 1989 |
Landau EM, Moriarty TM, Roberts JL, Gillo B, Sealfon S, Iyengar R. Expression of brain cholecystokinin receptors in frog oocytes Biological Psychiatry. 25: A130-A131. DOI: 10.1016/0006-3223(89)91749-6 |
0.319 |
|
| 1988 |
Moriarty TM, Gillo B, Sealfon S, Roberts JL, Blitzer RD, Landau EM. Functional expression of brain cholecystokinin and bombesin receptors in Xenopus oocytes. Brain Research. 464: 75-9. PMID 2902910 DOI: 10.1016/0169-328X(88)90021-6 |
0.337 |
|
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