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Francis C. Szoka, Jr. - Publications

Affiliations: 
Bioengineering University of California, San Francisco, San Francisco, CA 
Area:
Biomedical, Pharmaceutical
Website:
https://cancer.ucsf.edu/people/profiles/szoka_francis.3681

152 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhou G, Chu S, Kohli A, Szoka FC, Gochin M. Biophysical studies of HIV-1 glycoprotein-41 interactions with peptides and small molecules - Effect of lipids and detergents. Biochimica Et Biophysica Acta. General Subjects. 129724. PMID 32889078 DOI: 10.1016/J.Bbagen.2020.129724  0.785
2018 Tang J, Srinivasan S, Yuan W, Ming R, Liu Y, Dai Z, Noble CO, Hayes ME, Zheng N, Jiang W, Szoka FC, Schwendeman A. Development of a flow-through USP 4 apparatus drug release assay for the evaluation of amphotericin B liposome. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 30481559 DOI: 10.1016/J.Ejpb.2018.11.010  0.322
2018 Dolor A, Kierstead P, Dai Z, Szoka FC. Correction: Sterol-modified PEG lipids: alteration of the bilayer anchoring moiety has an unexpected effect on liposome circulation. Chemical Communications (Cambridge, England). PMID 30387791 DOI: 10.1039/C8Cc90487A  0.399
2018 Dolor A, Kierstead P, Dai Z, Szoka FC. Sterol-modified PEG lipids: alteration of the bilayer anchoring moiety has an unexpected effect on liposome circulation. Chemical Communications (Cambridge, England). PMID 30288531 DOI: 10.1039/c8cc05011b  0.322
2018 Dolor A, Szoka FC. Digesting a Path Forward: The Utility of Collagenase Tumor Treatment for Improved Drug Delivery. Molecular Pharmaceutics. PMID 29767984 DOI: 10.1021/Acs.Molpharmaceut.8B00319  0.311
2017 Shaghaghi M, Keyvanloo A, Huang Z, Szoka FC, Thewalt JL. Constrained vs. free cholesterol in DPPC membranes: a comparison of chain ordering ability using deuterium NMR. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 29120186 DOI: 10.1021/Acs.Langmuir.7B03299  0.376
2017 Iman M, Huang Z, Alavizadeh SH, Szoka FC, Jaafari MR. Study of Biodistribution and in vivo Anti-leishmanial Activity of a Distigmasterylhemisuccinoyl-glycero-phosphocholine Liposome-intercalated Amphotericin B. Antimicrobial Agents and Chemotherapy. PMID 28630182 DOI: 10.1128/Aac.02525-16  0.319
2017 Kieler-Ferguson HM, Chan D, Sockolosky J, Finney L, Maxey E, Vogt S, Szoka FC. Encapsulation, controlled release, and antitumor efficacy of cisplatin delivered in liposomes composed of sterol-modified phospholipids. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28263913 DOI: 10.1016/J.Ejps.2017.03.003  0.429
2016 Tiffany M, Szoka FC. Co-localization of Fluorescent Labeled Lipid Nanoparticles with Specifically Tagged Subcellular Compartments by Single Particle Tracking at Low Nanoparticle to Cell Ratios. Journal of Drug Targeting. 1-21. PMID 27600702 DOI: 10.1080/1061186X.2016.1233976  0.801
2016 Yuan W, Kuai R, Dai Z, Yuan Y, Zheng N, Jiang W, Noble C, Hayes M, Szoka FC, Schwendeman A. Development of a Flow-Through USP-4 Apparatus Drug Release Assay to Evaluate Doxorubicin Liposomes. The Aaps Journal. PMID 27485642 DOI: 10.1208/S12248-016-9958-2  0.323
2016 Lee S, Kivimäe S, Dolor A, Szoka FC. Macrophage-based cell therapies: The long and winding road. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27422609 DOI: 10.1016/J.Jconrel.2016.07.018  0.308
2015 Kierstead PH, Okochi H, Venditto VJ, Chuong TC, Kivimae S, Fréchet JM, Szoka FC. The effect of polymer backbone chemistry on the induction of the accelerated blood clearance in polymer modified liposomes. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26093095 DOI: 10.1016/J.Jconrel.2015.06.023  0.676
2015 Sockolosky JT, Szoka FC. The neonatal Fc receptor, FcRn, as a target for drug delivery and therapy. Advanced Drug Delivery Reviews. 91: 109-24. PMID 25703189 DOI: 10.1016/J.Addr.2015.02.005  0.333
2015 Kivimae S, Lee S, Szoka FC. 229. Engineered Macrophage-Based Cell Therapy for Cancer Treatment Molecular Therapy. 23: S90. DOI: 10.1016/S1525-0016(16)33834-5  0.333
2014 Sockolosky JT, Kivimäe S, Szoka FC. Fusion of a short peptide that binds immunoglobulin G to a recombinant protein substantially increases its plasma half-life in mice. Plos One. 9: e102566. PMID 25057984 DOI: 10.1371/Journal.Pone.0102566  0.32
2014 Venditto VJ, Dolor A, Kohli A, Salentinig S, Boyd BJ, Szoka FC. Sulfated quaternary amine lipids: a new class of inverse charge zwitterlipids. Chemical Communications (Cambridge, England). 50: 9109-11. PMID 24984814 DOI: 10.1039/C4Cc02866J  0.8
2014 Venditto VJ, Wieczorek L, Molnar S, Teque F, Landucci G, Watson DS, Forthal D, Polonis VR, Levy JA, Szoka FC. Chemically modified peptides based on the membrane-proximal external region of the HIV-1 envelope induce high-titer, epitope-specific nonneutralizing antibodies in rabbits. Clinical and Vaccine Immunology : Cvi. 21: 1086-93. PMID 24872518 DOI: 10.1128/Cvi.00320-14  0.685
2014 Kohli AG, Kivimäe S, Tiffany MR, Szoka FC. Improving the distribution of Doxil® in the tumor matrix by depletion of tumor hyaluronan. Journal of Controlled Release : Official Journal of the Controlled Release Society. 191: 105-14. PMID 24852095 DOI: 10.1016/J.Jconrel.2014.05.019  0.765
2014 Kohli AG, Kierstead PH, Venditto VJ, Walsh CL, Szoka FC. Designer lipids for drug delivery: from heads to tails. Journal of Controlled Release : Official Journal of the Controlled Release Society. 190: 274-87. PMID 24816069 DOI: 10.1016/J.Jconrel.2014.04.047  0.804
2014 Kohli AG, Kieler-Ferguson HM, Chan D, Szoka FC. A robust and quantitative method for tracking liposome contents after intravenous administration. Journal of Controlled Release : Official Journal of the Controlled Release Society. 176: 86-93. PMID 24368300 DOI: 10.1016/J.Jconrel.2013.12.014  0.806
2014 Guo X, Gagne L, Chen H, Szoka FC. Novel ortho ester-based, pH-sensitive cationic lipid for gene delivery in vitro and in vivo. Journal of Liposome Research. 24: 90-8. PMID 24188532 DOI: 10.3109/08982104.2013.848886  0.361
2013 Kieler-Ferguson HM, Fréchet JMJ, Szoka FC. Clinical developments of chemotherapeutic nanomedicines: Polymers and liposomes for delivery of camptothecins and platinum (II) drugs Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 5: 130-138. PMID 23335566 DOI: 10.1002/Wnan.1209  0.35
2013 Walsh CL, Nguyen J, Tiffany MR, Szoka FC. Synthesis, characterization, and evaluation of ionizable lysine-based lipids for siRNA delivery. Bioconjugate Chemistry. 24: 36-43. PMID 23176544 DOI: 10.1021/Bc300346H  0.812
2013 Venditto VJ, Watson DS, Motion M, Montefiori D, Szoka FC. Rational design of membrane proximal external region lipopeptides containing chemical modifications for HIV-1 vaccination. Clinical and Vaccine Immunology : Cvi. 20: 39-45. PMID 23114698 DOI: 10.1128/Cvi.00615-12  0.684
2013 Venditto VJ, Szoka FC. Cancer nanomedicines: so many papers and so few drugs! Advanced Drug Delivery Reviews. 65: 80-8. PMID 23036224 DOI: 10.1016/J.Addr.2012.09.038  0.693
2012 Sockolosky JT, Tiffany MR, Szoka FC. Engineering neonatal Fc receptor-mediated recycling and transcytosis in recombinant proteins by short terminal peptide extensions. Proceedings of the National Academy of Sciences of the United States of America. 109: 16095-100. PMID 22991460 DOI: 10.1073/Pnas.1208857109  0.76
2012 Motion JP, Nguyen J, Szoka FC. Phosphatase-triggered fusogenic liposomes for cytoplasmic delivery of cell-impermeable compounds. Angewandte Chemie (International Ed. in English). 51: 9047-51. PMID 22887437 DOI: 10.1002/Anie.201204198  0.704
2012 Nguyen J, Walsh CL, Motion JP, Perttu EK, Szoka F. Controlled nucleation of lipid nanoparticles. Pharmaceutical Research. 29: 2236-48. PMID 22544683 DOI: 10.1007/S11095-012-0752-2  0.79
2012 Walsh CL, Nguyen J, Szoka FC. Synthesis and characterization of novel zwitterionic lipids with pH-responsive biophysical properties. Chemical Communications (Cambridge, England). 48: 5575-7. PMID 22538384 DOI: 10.1039/C2Cc31710A  0.802
2012 Nguyen J, Szoka FC. Nucleic acid delivery: the missing pieces of the puzzle? Accounts of Chemical Research. 45: 1153-62. PMID 22428908 DOI: 10.1021/Ar3000162  0.698
2012 Perttu EK, Kohli AG, Szoka FC. Inverse-phosphocholine lipids: a remix of a common phospholipid. Journal of the American Chemical Society. 134: 4485-8. PMID 22364493 DOI: 10.1021/Ja210989H  0.799
2012 Kohli AG, Walsh CL, Szoka FC. Synthesis and characterization of betaine-like diacyl lipids: zwitterionic lipids with the cationic amine at the bilayer interface. Chemistry and Physics of Lipids. 165: 252-9. PMID 22301334 DOI: 10.1016/J.Chemphyslip.2012.01.005  0.815
2012 Huang Z, Li W, Szoka FC. Asymmetric 1-alkyl-2-acyl phosphatidylcholine: a helper lipid for enhanced non-viral gene delivery. International Journal of Pharmaceutics. 427: 64-70. PMID 21718766 DOI: 10.1016/J.Ijpharm.2011.06.022  0.441
2011 Perttu EK, Szoka FC. Zwitterionic sulfobetaine lipids that form vesicles with salt-dependent thermotropic properties. Chemical Communications (Cambridge, England). 47: 12613-5. PMID 22045250 DOI: 10.1039/C1Cc15804J  0.818
2011 Foglia F, Barlow DJ, Szoka FC, Huang Z, Rogers SE, Lawrence MJ. Structural studies of the monolayers and bilayers formed by a novel cholesterol-phospholipid chimera. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 8275-81. PMID 21634402 DOI: 10.1021/La200739Y  0.389
2011 Riviere K, Kieler-Ferguson HM, Jerger K, Szoka FC. Anti-tumor activity of liposome encapsulated fluoroorotic acid as a single agent and in combination with liposome irinotecan. Journal of Controlled Release : Official Journal of the Controlled Release Society. 153: 288-96. PMID 21600250 DOI: 10.1016/J.Jconrel.2011.05.005  0.795
2011 Iman M, Huang Z, Szoka FC, Jaafari MR. Characterization of the colloidal properties, in vitro antifungal activity, antileishmanial activity and toxicity in mice of a di-stigma-steryl-hemi-succinoyl-glycero-phosphocholine liposome-intercalated amphotericin B. International Journal of Pharmaceutics. 408: 163-72. PMID 21277963 DOI: 10.1016/J.Ijpharm.2011.01.044  0.346
2011 Watson DS, Platt VM, Cao L, Venditto VJ, Szoka FC. Antibody response to polyhistidine-tagged peptide and protein antigens attached to liposomes via lipid-linked nitrilotriacetic acid in mice. Clinical and Vaccine Immunology : Cvi. 18: 289-97. PMID 21159923 DOI: 10.1128/Cvi.00425-10  0.772
2011 Floyd WC, Datta GK, Imamura S, Kieler-Ferguson HM, Jerger K, Patterson AW, Fox ME, Szoka FC, Fréchet JM, Ellman JA. Chemotherapeutic evaluation of a synthetic tubulysin analogue-dendrimer conjugate in c26 tumor bearing mice. Chemmedchem. 6: 49-53. PMID 20973119 DOI: 10.1002/Cmdc.201000377  0.326
2011 Riviere K, Huang Z, Jerger K, Macaraeg N, Szoka FC. Antitumor effect of folate-targeted liposomal doxorubicin in KB tumor-bearing mice after intravenous administration. Journal of Drug Targeting. 19: 14-24. PMID 20353291 DOI: 10.3109/10611861003733953  0.785
2010 Platt V, Huang Z, Cao L, Tiffany M, Riviere K, Szoka FC. Influence of multivalent nitrilotriacetic acid lipid-ligand affinity on the circulation half-life in mice of a liposome-attached His6-protein. Bioconjugate Chemistry. 21: 892-902. PMID 20384362 DOI: 10.1021/Bc900448F  0.769
2010 Van Der Poll DG, Kieler-Ferguson HM, Floyd WC, Guillaudeu SJ, Jerger K, Szoka FC, Fréchet JM. Design, synthesis, and biological evaluation of a robust, biodegradable dendrimer Bioconjugate Chemistry. 21: 764-773. PMID 20353169 DOI: 10.1021/Bc900553N  0.335
2009 Huang Z, Hwang P, Watson DS, Cao L, Szoka FC. Tris-nitrilotriacetic acids of subnanomolar affinity toward hexahistidine tagged molecules. Bioconjugate Chemistry. 20: 1667-72. PMID 19650657 DOI: 10.1021/Bc900309N  0.306
2009 Watson DS, Huang Z, Szoka FC. All-trans retinoic acid potentiates the antibody response in mice to a lipopeptide antigen adjuvanted with liposomal lipid A. Immunology and Cell Biology. 87: 630-3. PMID 19597529 DOI: 10.1038/Icb.2009.48  0.345
2009 Fox ME, Guillaudeu S, Fréchet JM, Jerger K, Macaraeg N, Szoka FC. Synthesis and in vivo antitumor efficacy of PEGylated poly(l-lysine) dendrimer-camptothecin conjugates. Molecular Pharmaceutics. 6: 1562-72. PMID 19588994 DOI: 10.1021/Mp9001206  0.312
2009 Fox ME, Szoka FC, Fréchet JM. Soluble polymer carriers for the treatment of cancer: the importance of molecular architecture. Accounts of Chemical Research. 42: 1141-51. PMID 19555070 DOI: 10.1021/Ar900035F  0.315
2009 Watson DS, Szoka FC. Role of lipid structure in the humoral immune response in mice to covalent lipid-peptides from the membrane proximal region of HIV-1 gp41. Vaccine. 27: 4672-83. PMID 19520200 DOI: 10.1016/J.Vaccine.2009.05.059  0.36
2009 Huang Z, Jaafari MR, Szoka FC. Disterolphospholipids: nonexchangeable lipids and their application to liposomal drug delivery. Angewandte Chemie (International Ed. in English). 48: 4146-9. PMID 19425026 DOI: 10.1002/Anie.200900111  0.427
2009 Park JI, Cao L, Platt VM, Huang Z, Stull RA, Dy EE, Sperinde JJ, Yokoyama JS, Szoka FC. Antitumor therapy mediated by 5-fluorocytosine and a recombinant fusion protein containing TSG-6 hyaluronan binding domain and yeast cytosine deaminase. Molecular Pharmaceutics. 6: 801-12. PMID 19265397 DOI: 10.1021/Mp800013C  0.776
2009 Cohen RN, van der Aa MA, Macaraeg N, Lee AP, Szoka FC. Quantification of plasmid DNA copies in the nucleus after lipoplex and polyplex transfection. Journal of Controlled Release : Official Journal of the Controlled Release Society. 135: 166-74. PMID 19211029 DOI: 10.1016/J.Jconrel.2008.12.016  0.6
2009 Cohen RN, van der Aa MAEM, Macaraeg N, Lee AP, Szoka FC. Corrigendum to "Quantification of plasmid DNA copies in the nucleus after lipoplex and polyplex transfection". [J. Control. Release 135 (2009) 166-174] (DOI:10.1016/j.jconrel.2008.12.016) Journal of Controlled Release. 138: 185. DOI: 10.1016/J.Jconrel.2009.05.014  0.582
2009 Platt VM, Szoka FC. Exploiting the Hyaluronan-CD44 Interaction for Cancer Therapy Hyaluronan in Cancer Biology. 379-403. DOI: 10.1016/B978-012374178-3.10020-1  0.772
2008 Huang Z, Szoka FC. Sterol-modified phospholipids: cholesterol and phospholipid chimeras with improved biomembrane properties. Journal of the American Chemical Society. 130: 15702-12. PMID 18950160 DOI: 10.1021/Ja8065557  0.423
2008 Platt VM, Szoka FC. Anticancer therapeutics: targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor. Molecular Pharmaceutics. 5: 474-86. PMID 18547053 DOI: 10.1021/Mp800024G  0.779
2008 MacKay JA, Li W, Huang Z, Dy EE, Huynh G, Tihan T, Collins R, Deen DF, Szoka FC. HIV TAT peptide modifies the distribution of DNA nanolipoparticles following convection-enhanced delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 893-900. PMID 18388927 DOI: 10.1038/Mt.2008.36  0.626
2008 Guillaudeu SJ, Fox ME, Haidar YM, Dy EE, Szoka FC, Fréchet JM. PEGylated dendrimers with core functionality for biological applications. Bioconjugate Chemistry. 19: 461-9. PMID 18173227 DOI: 10.1021/Bc700264G  0.35
2007 Chen H, Zhang H, McCallum CM, Szoka FC, Guo X. Unsaturated cationic ortho esters for endosome permeation in gene delivery. Journal of Medicinal Chemistry. 50: 4269-78. PMID 17691717 DOI: 10.1021/Jm060128C  0.434
2007 Li W, Szoka FC. Lipid-based nanoparticles for nucleic acid delivery. Pharmaceutical Research. 24: 438-49. PMID 17252188 DOI: 10.1007/S11095-006-9180-5  0.395
2006 Li W, Szoka FC. Bioresponsive targeted charge neutral lipid vesicles for systemic gene delivery. Csh Protocols. 2006. PMID 22485781 DOI: 10.1101/Pdb.Prot4450  0.435
2006 Huang Z, Park JI, Watson DS, Hwang P, Szoka FC. Facile synthesis of multivalent nitrilotriacetic acid (NTA) and NTA conjugates for analytical and drug delivery applications. Bioconjugate Chemistry. 17: 1592-600. PMID 17105240 DOI: 10.1021/Bc0602228  0.375
2006 Lee CC, Gillies ER, Fox ME, Guillaudeu SJ, Fréchet JM, Dy EE, Szoka FC. A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas. Proceedings of the National Academy of Sciences of the United States of America. 103: 16649-54. PMID 17075050 DOI: 10.1073/Pnas.0607705103  0.323
2006 Lee CC, Cramer AT, Szoka FC, Fréchet JM. An intramolecular cyclization reaction is responsible for the in vivo inefficacy and apparent pH insensitive hydrolysis kinetics of hydrazone carboxylate derivatives of doxorubicin. Bioconjugate Chemistry. 17: 1364-8. PMID 16984149 DOI: 10.1021/Bc060117Y  0.305
2006 Ruhela D, Riviere K, Szoka FC. Efficient synthesis of an aldehyde functionalized hyaluronic acid and its application in the preparation of hyaluronan-lipid conjugates. Bioconjugate Chemistry. 17: 1360-3. PMID 16984148 DOI: 10.1021/Bc0600721  0.796
2006 Huang Z, Guo X, Li W, MacKay JA, Szoka FC. Acid-triggered transformation of diortho ester phosphocholine liposome. Journal of the American Chemical Society. 128: 60-1. PMID 16390121 DOI: 10.1021/Ja057024W  0.631
2006 Huynh GH, Deen DF, Szoka FC. Barriers to carrier mediated drug and gene delivery to brain tumors. Journal of Controlled Release : Official Journal of the Controlled Release Society. 110: 236-59. PMID 16318895 DOI: 10.1016/J.Jconrel.2005.09.053  0.322
2005 Cohen RN, Rashkin MJ, Wen X, Szoka FC. Molecular motors as drug delivery vehicles. Drug Discovery Today. Technologies. 2: 111-8. PMID 24981763 DOI: 10.1016/J.Ddtec.2005.04.003  0.592
2005 Lee CC, MacKay JA, Fréchet JM, Szoka FC. Designing dendrimers for biological applications. Nature Biotechnology. 23: 1517-26. PMID 16333296 DOI: 10.1038/Nbt1171  0.566
2005 Huang Z, Li W, MacKay JA, Szoka FC. Thiocholesterol-based lipids for ordered assembly of bioresponsive gene carriers. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 409-17. PMID 15727937 DOI: 10.1016/J.Ymthe.2004.10.013  0.633
2005 MacKay JA, Deen DF, Szoka FC. Distribution in brain of liposomes after convection enhanced delivery; modulation by particle charge, particle diameter, and presence of steric coating. Brain Research. 1035: 139-53. PMID 15722054 DOI: 10.1016/J.Brainres.2004.12.007  0.641
2005 Li W, Huang Z, MacKay JA, Grube S, Szoka FC. Low-pH-sensitive poly(ethylene glycol) (PEG)-stabilized plasmid nanolipoparticles: effects of PEG chain length, lipid composition and assembly conditions on gene delivery. The Journal of Gene Medicine. 7: 67-79. PMID 15515149 DOI: 10.1002/Jgm.634  0.64
2004 Guo X, Huang Z, Szoka FC. Improved preparation of PEG-diortho ester-diacyl glycerol conjugates. Methods in Enzymology. 387: 147-52. PMID 15172162 DOI: 10.1016/S0076-6879(04)87009-5  0.302
2004 Li W, Nicol F, Szoka FC. GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery. Advanced Drug Delivery Reviews. 56: 967-85. PMID 15066755 DOI: 10.1016/J.Addr.2003.10.041  0.385
2004 Eliaz RE, Nir S, Marty C, Szoka FC. Determination and modeling of kinetics of cancer cell killing by doxorubicin and doxorubicin encapsulated in targeted liposomes. Cancer Research. 64: 711-8. PMID 14744789 DOI: 10.1158/0008-5472.Can-03-0654  0.327
2003 Mackay JA, Szoka FC. HIV TAT Protein Transduction Domain Mediated Cell Binding and Intracellular Delivery of Nanoparticles. Journal of Dispersion Science and Technology. 24: 465-473. PMID 20808712 DOI: 10.1081/Dis-120021802  0.608
2003 Guo X, Szoka FC. Chemical approaches to triggerable lipid vesicles for drug and gene delivery. Accounts of Chemical Research. 36: 335-41. PMID 12755643 DOI: 10.1021/ar9703241  0.307
2003 Choi JS, MacKay JA, Szoka FC. Low-pH-sensitive PEG-stabilized plasmid-lipid nanoparticles: preparation and characterization. Bioconjugate Chemistry. 14: 420-9. PMID 12643753 DOI: 10.1021/Bc025625W  0.619
2003 Guo X, MacKay JA, Szoka FC. Mechanism of pH-triggered collapse of phosphatidylethanolamine liposomes stabilized by an ortho ester polyethyleneglycol lipid. Biophysical Journal. 84: 1784-95. PMID 12609880 DOI: 10.1016/S0006-3495(03)74986-8  0.652
2002 Bronich TK, Ouyang M, Kabanov VA, Eisenberg A, Szoka FC, Kabanov AV. Synthesis of vesicles on polymer template. Journal of the American Chemical Society. 124: 11872-3. PMID 12358530 DOI: 10.1021/Ja020509P  0.337
2002 Padilla De Jesús OL, Ihre HR, Gagne L, Fréchet JM, Szoka FC. Polyester dendritic systems for drug delivery applications: in vitro and in vivo evaluation. Bioconjugate Chemistry. 13: 453-61. PMID 12009933 DOI: 10.1021/Bc010103M  0.346
2002 Ihre HR, Padilla De Jesús OL, Szoka FC, Fréchet JM. Polyester dendritic systems for drug delivery applications: design, synthesis, and characterization. Bioconjugate Chemistry. 13: 443-52. PMID 12009932 DOI: 10.1021/Bc010102U  0.35
2000 Urtti A, Polansky J, Lui GM, Szoka FC. Gene delivery and expression in human retinal pigment epithelial cells: Effects of synthetic carriers, serum, extracellular matrix and viral promoters Journal of Drug Targeting. 7: 413-421. PMID 10758912 DOI: 10.3109/10611860009102216  0.325
2000 Nicol F, Nir S, Szoka FC. Effect of phospholipid composition on an amphipathic peptide-mediated pore formation in bilayer vesicles Biophysical Journal. 78: 818-829. PMID 10653794 DOI: 10.1016/S0006-3495(00)76639-2  0.378
2000 Ouyang M, Remy JS, Szoka FC. Controlled template-assisted assembly of plasmid DNA into nanometric particles with high DNA concentration. Bioconjugate Chemistry. 11: 104-12. PMID 10639092 DOI: 10.1021/Bc990101Q  0.308
1999 Hirota S, De Ilarduya CT, Barron LG, Szoka FC. Simple mixing device to reproducibly prepare cationic lipid-DNA complexes (lipoplexes) Biotechniques. 27: 286-290. PMID 10457833 DOI: 10.2144/99272Bm16  0.325
1999 Barron LG, Gagné L, Szoka FC. Lipoplex-mediated gene delivery to the lung occurs within 60 minutes of intravenous administration Human Gene Therapy. 10: 1683-1694. PMID 10428213 DOI: 10.1089/10430349950017680  0.343
1999 Xu Y, Hui SW, Frederik P, Szoka FC. Physicochemical characterization and purification of cationic lipoplexes Biophysical Journal. 77: 341-353. PMID 10388762 DOI: 10.1016/S0006-3495(99)76894-3  0.626
1999 Nir S, Nicol F, Szoka FC. Surface aggregation and membrane penetration by peptides: Relation to pore formation and fusion Molecular Membrane Biology. 16: 95-101. PMID 10332743 DOI: 10.1080/096876899294814  0.325
1999 Nicol F, Nir S, Szoka FC. Orientation of the pore-forming peptide GALA in POPC vesicles determined by a BODIPY-avidin/biotin binding assay Biophysical Journal. 76: 2121-2141. PMID 10096907 DOI: 10.1016/S0006-3495(99)77368-6  0.343
1998 Peschka R, Dennehy C, Szoka FC. A simple in vitro model to study the release kinetics of liposome encapsulated material Journal of Controlled Release. 56: 41-51. PMID 9801428 DOI: 10.1016/S0168-3659(98)00067-4  0.333
1998 Wang J, Guo X, Xu Y, Barron L, Szoka FC. Synthesis and characterization of long chain alkyl acyl carnitine esters. Potentially biodegradable cationic lipids for use in gene delivery Journal of Medicinal Chemistry. 41: 2207-2215. PMID 9632353 DOI: 10.1021/Jm950802I  0.619
1998 Barron GL, Meyer KB, Szoka FC. Effects of complement depletion on the pharmacokinetics and gene delivery mediated by cationic lipid-DNA complexes Human Gene Therapy. 9: 315-323. PMID 9508049 DOI: 10.1089/Hum.1998.9.3-315  0.343
1998 Zelphati O, Uyechi LS, Barron LG, Szoka FC. Effect of serum components on the physico-chemical properties of cationic lipid/oligonucleotide complexes and on their interactions with cells Biochimica Et Biophysica Acta - Lipids and Lipid Metabolism. 1390: 119-133. PMID 9507083 DOI: 10.1016/S0005-2760(97)00169-0  0.407
1998 Szoka FC. Commentary: Rantosomes and ravosomes Journal of Liposome Research. 8: vii-ix. DOI: 10.3109/08982109809035536  0.388
1997 Wyman TB, Nicol F, Zelphati O, Scaria PV, Plank C, Szoka FC. Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers Biochemistry. 36: 3008-3017. PMID 9062132 DOI: 10.1021/Bi9618474  0.352
1997 Zelphati O, Szoka FC. Cationic liposomes as an oligonucleotide carrier: Mechanism of action Journal of Liposome Research. 7: 31-49. DOI: 10.3109/08982109709035480  0.447
1997 Davis SC, Szoka FC. Conditionally stable liposomes for drug delivery Polymeric Materials Science and Engineering, Proceedings of the Acs Division of Polymeric Materials Science and Engineering. 76: 503.  0.336
1996 Nicol F, Nir S, Szoka FC. Effect of cholesterol and charge on pore formation in bilayer vesicles by a pH-sensitive peptide Biophysical Journal. 71: 3288-3301. PMID 8968598 DOI: 10.1016/S0006-3495(96)79521-8  0.381
1996 Tang MX, Redemann CT, Szoka FC. In vitro gene delivery by degraded polyamidoamine dendrimers Bioconjugate Chemistry. 7: 703-714. PMID 8950489 DOI: 10.1021/Bc9600630  0.304
1996 Zelphati O, Szoka FC. Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids Pharmaceutical Research. 13: 1367-1372. PMID 8893276 DOI: 10.1023/A:1016026101195  0.413
1996 Zelphati O, Szoka FC. Mechanism of oligonucleotide release from cationic liposomes Proceedings of the National Academy of Sciences of the United States of America. 93: 11493-11498. PMID 8876163 DOI: 10.1073/Pnas.93.21.11493  0.442
1996 Plank C, Mechtler K, Szoka FC, Wagner E. Activation of the complement system by synthetic DNA complexes: A potential barrier for intravenous gene delivery Human Gene Therapy. 7: 1437-1446. PMID 8844203 DOI: 10.1089/Hum.1996.7.12-1437  0.332
1996 Xu Y, Szoka FC. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection Biochemistry. 35: 5616-5623. PMID 8639519 DOI: 10.1021/Bi9602019  0.614
1996 Szoka FC, Xu Y, Zelphati O. How are nucleic acids released in cells from cationic lipid-nucleic acid complexes? Journal of Liposome Research. 6: 567-587. DOI: 10.3109/08982109609031137  0.636
1996 Zelphati O, Szoka FC. Liposomes as a carrier for intracellular delivery of antisense oligonucleotides: A real or magic bullet? Journal of Controlled Release. 41: 99-119. DOI: 10.1016/0168-3659(96)01361-2  0.394
1995 Stull RA, Szoka FC. Antigene, ribozyme and aptamer nucleic acid drugs: progress and prospects. Pharmaceutical Research. 12: 465-483. PMID 7596980 DOI: 10.1023/A:1016281324761  0.344
1994 Fattal E, Nir S, Parente RA, Szoka FC. Pore-forming peptides induce rapid phospholipid flip-flop in membranes Biochemistry®. 6721-6731. PMID 8204607 DOI: 10.1021/Bi00187A044  0.349
1994 Chu CJ, Szoka FC. Ph-sensitive liposomes Journal of Liposome Research. 4: 361-395. DOI: 10.3109/08982109409037050  0.419
1993 Haensler J, Szoka FC. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture Bioconjugate Chemistry. 4: 372-379. PMID 8274523 DOI: 10.1021/Bc00023A012  0.343
1993 Legendre JY, Szoka FC. Cyclic amphipathic peptide-DNA complexes mediate high-efficiency transfection of adherent mammalian cells Proceedings of the National Academy of Sciences of the United States of America. 90: 893-897. PMID 7679217 DOI: 10.1073/Pnas.90.3.893  0.325
1993 Szoka FC, Tang M. Amphotericin b formulated in liposomes and lipid based systems: A review Journal of Liposome Research. 3: 363-375. DOI: 10.3109/08982109309150726  0.444
1992 Woodle MC, Storm G, Newman MS, Jekot JJ, Collins LR, Martin FJ, Szoka FC. Prolonged systemic delivery of peptide drugs by long-circulating liposomes: illustration with vasopressin in the Brattleboro rat. Pharmaceutical Research. 9: 260-5. PMID 1553352 DOI: 10.1023/A:1018953810705  0.35
1992 Kim A, Szoka FC. Amino Acid Side-Chain Contributions to Free Energy of Transfer of Tripeptides from Water to Octanol Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 9: 504-514. PMID 1495896 DOI: 10.1023/A:1015892313856  0.303
1992 Legendre JY, Szoka FC. Delivery of Plasmid DNA into Mammalian Cell Lines Using pH-Sensitive Liposomes: Comparison with Cationic Liposomes Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 9: 1235-1242. PMID 1448419 DOI: 10.1023/A:1015836829670  0.355
1992 Chu CJ, Szoka FC. Antiviral activity and pharmacokinetics of liposome-encapsulated phosphonoformate in rauscher murine leukemia virus-infected mice Journal of Liposome Research. 2: 67-92. DOI: 10.3109/08982109209039902  0.323
1991 Goormaghtigh E, De Meutter J, Szoka F, Cabiaux V, Parente RA, Ruysschaert JM. Secondary structure and orientation of the amphipathic peptide GALA in lipid structures. An infrared-spectroscopic approach. European Journal of Biochemistry / Febs. 195: 421-9. PMID 1997324 DOI: 10.1111/J.1432-1033.1991.Tb15721.X  0.343
1991 Green PG, Hinz RS, Kim A, Szoka FC, Guy RH. lontophoretic Delivery of a Series of Tripeptides Across the Skin in Vitro Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 8: 1121-1127. PMID 1788157 DOI: 10.1023/A:1015846100305  0.316
1990 Parente RA, Nir S, Szoka FC. Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA Biochemistry. 29: 8720-8728. PMID 2271552 DOI: 10.1021/Bi00489A031  0.374
1990 Parente RA, Nadasdi L, Subbarao NK, Szoka FC. Association of a pH-sensitive peptide with membrane vesicles: Role of amino acid sequence Biochemistry. 29: 8713-8719. PMID 2271551 DOI: 10.1021/Bi00489A030  0.348
1990 Chu CJ, Dijkstra J, Lai MZ, Hong K, Szoka FC. Efficiency of cytoplasmic delivery by pH-sensitive liposomes to cells in culture. Pharmaceutical Research. 7: 824-34. PMID 2172955 DOI: 10.1023/A:1015908831507  0.346
1990 Chin DJ, Green GA, Zon G, Szoka FC, Straubinger RM. Rapid nuclear accumulation of injected oligodeoxyribonucleotides New Biologist. 2: 1091-1100. PMID 1708281  0.511
1990 Knepp VM, Szoka FC, Guy RH. Controlled drug release from a novel liposomal delivery system. II. Transdermal delivery characteristics Journal of Controlled Release. 12: 25-30. DOI: 10.1016/0168-3659(90)90179-W  0.422
1989 Roe JN, Szoka FC, Verkman AS. Optical measurement of aqueous potassium concentration by a hydrophobic indicator in lipid vesicles Biophysical Chemistry. 33: 295-302. PMID 2804247 DOI: 10.1016/0301-4622(89)80031-6  0.306
1989 Szoka FC, Jacobson K, Papahadjopoulos D. The use of aqueous space markers to determine the mechanism of interaction between phospholipid vesicles and cells Bba - Biomembranes. 551: 295-303. DOI: 10.1016/0005-2736(89)90007-2  0.587
1988 Subbarao NK, Fielding CJ, Hamilton RL, Szoka FC. Lecithin:cholesterol acyltransferase activation by synthetic amphipathic peptides. Proteins. 3: 187-98. PMID 3255105 DOI: 10.1002/Prot.340030307  0.384
1988 Dijkstra J, Larrick JW, Ryan JL, Szoka FC. Incorporation of LPS in liposomes diminishes its ability to induce tumoricidal activity and tumor necrosis factor secretion in murine macrophages Journal of Leukocyte Biology. 43: 436-444. PMID 3131472 DOI: 10.1002/Jlb.43.5.436  0.306
1988 Szoka FC, Chun-Jung Chu. Increased efficacy of phosphonoformate and phosphonoacetate inhibition of herpes simplex virus type 2 replication by encapsulation in liposomes Antimicrobial Agents and Chemotherapy. 32: 858-864. PMID 2843083 DOI: 10.1128/Aac.32.6.858  0.419
1988 Knepp VM, Hinz RS, Szoka FC, Guy RH. Controlled drug release from a novel liposomal delivery system. I. Investigation of transdermal potential Journal of Controlled Release. 5: 211-221. DOI: 10.1016/0168-3659(88)90020-X  0.383
1987 Bentz J, Ellens H, Szoka FC. Destabilization of phosphatidylethanolamine-containing liposomes: Hexagonal phase and asymmetric membranes Biochemistry. 26: 2105-2116. PMID 3620441 DOI: 10.1021/Bi00382A008  0.397
1987 Szoka FC, Milholland D, Barza M. Effect of lipid composition and liposome size on toxicity and in vitro fungicidal activity of liposome-intercalated amphotericin B Antimicrobial Agents and Chemotherapy. 31: 421-429. PMID 3579259 DOI: 10.1128/Aac.31.3.421  0.428
1987 Dijkstra J, Mellors JW, Ryan JL, Szoka FC. Modulation of the biological activity of bacterial endotoxin by incorporation into liposomes Journal of Immunology. 138: 2663-2670. PMID 3494081  0.327
1987 Szoka FC, Jones CS. [14] Uptake of liposome-encapsulated agents Methods in Enzymology. 149: 143-147. PMID 3121982 DOI: 10.1016/0076-6879(87)49052-6  0.357
1987 Subbarao NK, Parente RA, Szoka FC, Nadasdi L, Pongracz K. pH-dependent bilayer destabilization by an amphipathic peptide. Biochemistry. 26: 2964-72. PMID 2886149 DOI: 10.1021/Bi00385A002  0.334
1986 Ellens H, Bentz J, Szoka FC. Destabilization of phosphatidylethanolamine liposomes at the hexagonal phase transition temperature Biochemistry. 25: 285-294. PMID 3954998 DOI: 10.1021/Bi00350A001  0.349
1986 Ellens H, Bentz J, Szoka FC. Fusion of phosphatidylethanolamine-containing liposomes and mechanism of the Lα-HII phase transition Biochemistry. 25: 4141-4147. PMID 3741846 DOI: 10.1021/Bi00362A023  0.372
1985 Ellens H, Bentz J, Szoka FC. H+- and Ca2+-induced fusion and destabilization of liposomes Biochemistry. 24: 3099-3106. PMID 4027232 DOI: 10.1021/Bi00334A005  0.36
1985 Lai MZ, Vail WJ, Szoka FC. Acid- and calcium-induced structural changes in phosphatidylethanolamine membranes stabilized by cholesteryl hemisuccinate Biochemistry. 24: 1654-1661. PMID 4005220 DOI: 10.1021/Bi00328A013  0.346
1985 Bentz J, Ellens H, Lai MZ, Szoka FC. On the correlation between HII phase and the contact-induced destabilization of phosphatidylethanolamine-containing membranes Proceedings of the National Academy of Sciences of the United States of America. 82: 5742-5745. PMID 3862092 DOI: 10.1073/Pnas.82.17.5742  0.369
1985 Lai MZ, Duzgunes N, Szoka FC. Effects of replacement of the hydroxyl group of cholesterol and tocopherol on the thermotropic behavior of phospholipid membranes Biochemistry. 24: 1646-1653. PMID 3839132 DOI: 10.1021/Bi00328A012  0.383
1984 Ellens H, Bentz J, Szoka FC. PH-Induced destabilization of phosphatidylethanolamine-containing liposomes: Role of bilayer contact Biochemistry. 23: 1532-1538. PMID 6722105 DOI: 10.1021/Bi00302A029  0.388
1984 Tremblay C, Barza M, Fiore C, Szoka F. Efficacy of liposome-intercalated amphotericin B in the treatment of systemic candidiasis in mice Antimicrobial Agents and Chemotherapy. 26: 170-173. PMID 6385839 DOI: 10.1128/Aac.26.2.170  0.304
1984 Larwood DJ, Szoka FC. Synthesis, characterization, and in vivo disposition of iodinatable polyethylene glycol derivatives: Differences in vivo as a function of chain length Journal of Labelled Compounds and Radiopharmaceuticals. 21: 603-614. DOI: 10.1002/Jlcr.2580210703  0.302
1983 Szoka FC, Mayhew E. Alteration of liposome disposition in vivo by bilayer situated carbohydrates Biochemical and Biophysical Research Communications. 110: 140-146. PMID 6687678 DOI: 10.1016/0006-291X(83)91271-8  0.348
1982 Olson F, Mayhew E, Maslow D, Rustum Y, Szoka F. Characterization, toxicity and therapeutic efficacy of adriamycin encapsulated in liposomes. European Journal of Cancer and Clinical Oncology. 18: 167-176. PMID 7201392 DOI: 10.1016/0277-5379(82)90060-8  0.38
1981 Rustum YM, Mayhew E, Szoka F, Campbell J. Inability of liposome encapsulated 1-β-d-arabinofuranosylcytosine nucleotides to overcome drug resistance in L1210 cells European Journal of Cancer and Clinical Oncology. 17: 809-817. PMID 7199474 DOI: 10.1016/0014-2964(81)90237-1  0.331
1981 Szoka F, Magnusson K, Wojcieszyn J, Hou Y, Derzko Z, Jacobson K. Use of lectins and polyethylene glycol for fusion of glycolipid-containing liposomes with eukaryotic cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 1685-1689. PMID 6940182 DOI: 10.1073/Pnas.78.3.1685  0.383
1980 Szoka F, Jacobson K, Derzko Z, Papahadjopoulos D. Fluorescence studies on the mechanism of liposome-cell interactions in vitro. Biochimica Et Biophysica Acta. 600: 1-18. PMID 7397162 DOI: 10.1016/0005-2736(80)90406-X  0.607
1980 Szoka F, Olson F, Heath T, Vail W, Mayhew E, Papahadjopoulos D. Preparation of unilamellar liposomes of intermediate size (0.1-0.2 mumol) by a combination of reverse phase evaporation and extrusion through polycarbonate membranes. Biochimica Et Biophysica Acta. 601: 559-71. PMID 6251878 DOI: 10.1016/0005-2736(80)90558-1  0.623
1979 Saffran M, Franco-Saenz R, Kong A, Papahadjopoulos D, Szoka F. A model for the study of the oral administration of peptide hormones. Canadian Journal of Biochemistry. 57: 548-53. PMID 314322 DOI: 10.1139/O79-069  0.518
1979 Near JA, Szoka FC, Olsen R, Ettinger MJ. Photoaffinity labeling of three renal cyclic 3',5'-adenosine monophosphate-binding proteins. Biochimica Et Biophysica Acta. 587: 522-39. PMID 228750 DOI: 10.1016/0304-4165(79)90006-0  0.683
1979 Olson F, Hunt CA, Szoka FC, Vail WJ, Papahadjopoulos D. Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes Bba - Biomembranes. 557: 9-23. PMID 95096 DOI: 10.1016/0005-2736(79)90085-3  0.585
1978 Szoka F, Papahadjopoulos D. Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation Proceedings of the National Academy of Sciences of the United States of America. 75: 4194-4198. PMID 279908 DOI: 10.1073/Pnas.75.9.4194  0.632
1978 Szoka FC, Ettinger MJ. Adenosine 3':5'-monophosphate-dependent phosphorylations of renal subcellular fractions. Differences between cortical and medullary membrane preparations Journal of Biological Chemistry. 253: 6536-6543. PMID 210188  0.652
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