Anthony J. Hickey - Publications

Affiliations: 
Biomedical Engineering Joint Program University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Biomedical

144 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Braunstein M, Hickey AJ, Ekins S. Why Wait? The Case for Treating Tuberculosis with Inhaled Drugs. Pharmaceutical Research. 36: 166. PMID 31650321 DOI: 10.1007/s11095-019-2704-6  0.36
2019 Walz A, Lukka PB, Pearce C, Creissen E, Braunstein M, Hickey AJ, Meibohm B, Gonzalez-Juarrero M. Sterilization of Mycobacterium tuberculosis infected samples using methanol preserves anti-tuberculosis drugs for subsequent pharmacological testing studies. Tuberculosis (Edinburgh, Scotland). 117: 52-55. PMID 31378268 DOI: 10.1016/j.tube.2019.06.002  0.36
2019 Stewart IE, Lukka PB, Liu J, Meibohm B, Gonzalez-Juarrero M, Braunstein MS, Lee RE, Hickey AJ. Development and Characterization of a Dry Powder Formulation for Anti-Tuberculosis Drug Spectinamide 1599. Pharmaceutical Research. 36: 136. PMID 31321552 DOI: 10.1007/s11095-019-2666-8  0.44
2018 Montgomery SA, Young EF, Durham PG, Zulauf KE, Rank L, Miller BK, Hayden JD, Lin FC, Welch JT, Hickey AJ, Braunstein M. Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis. Plos One. 13: e0204495. PMID 30261007 DOI: 10.1371/journal.pone.0204495  0.36
2018 Kukut Hatipoglu M, Hickey AJ, Garcia-Contreras L. Pharmacokinetics and pharmacodynamics of high doses of inhaled dry powder drugs. International Journal of Pharmaceutics. 549: 306-316. PMID 30077761 DOI: 10.1016/j.ijpharm.2018.07.050  0.52
2018 Schroeter JD, Sheth P, Hickey AJ, Asgharian B, Price OT, Holt JT, Conti DS, Saluja B. Effects of Formulation Variables on Lung Dosimetry of Albuterol Sulfate Suspension and Beclomethasone Dipropionate Solution Metered Dose Inhalers. Aaps Pharmscitech. PMID 29858973 DOI: 10.1208/s12249-018-1071-7  0.36
2016 Young EF, Perkowski E, Malik S, Hayden JD, Durham PG, Zhong L, Welch JT, Braunstein MS, Hickey AJ. Inhaled Pyrazinoic Acid Esters for the Treatment of Tuberculosis. Pharmaceutical Research. PMID 27351427 DOI: 10.1007/s11095-016-1974-5  1
2016 Durham PG, Young EF, Braunstein MS, Welch JT, Hickey AJ. A dry powder combination of pyrazinoic acid and its n-propyl ester for aerosol administration to animals. International Journal of Pharmaceutics. PMID 27130363 DOI: 10.1016/j.ijpharm.2016.04.063  1
2016 Wood R, Morrow C, Barry CE, Bryden WA, Call CJ, Hickey AJ, Rodes CE, Scriba TJ, Blackburn J, Issarow C, Mulder N, Woodward J, Moosa A, Singh V, Mizrahi V, et al. Real-Time Investigation of Tuberculosis Transmission: Developing the Respiratory Aerosol Sampling Chamber (RASC). Plos One. 11: e0146658. PMID 26807816 DOI: 10.1371/journal.pone.0146658  1
2015 Durham PG, Zhang Y, German N, Mortensen N, Dhillon J, Mitchison DA, Fourie PB, Hickey AJ. Spray Dried Aerosol Particles of Salts for Tuberculosis Therapy. Molecular Pharmaceutics. PMID 26098136 DOI: 10.1021/acs.molpharmaceut.5b00118  1
2015 Ziffels S, Bemelmans NL, Durham PG, Hickey AJ. In vitro dry powder inhaler formulation performance considerations. Journal of Controlled Release : Official Journal of the Controlled Release Society. 199: 45-52. PMID 25497311 DOI: 10.1016/j.jconrel.2014.11.035  1
2015 Garcia Contreras L, Sung J, Ibrahim M, Elbert K, Edwards D, Hickey A. Pharmacokinetics of Inhaled Rifampicin Porous Particles for Tuberculosis Treatment: Insight into Rifampicin Absorption from the Lungs of Guinea Pigs Molecular Pharmaceutics. 12: 2642-2650. DOI: 10.1021/acs.molpharmaceut.5b00046  1
2015 Achkar J, Beverley P, Boom H, Evans T, Hanekom W, Hickey A, Hoft D, Lakhani D, Lin PL, Ramanathan R, Henao-Restrepo AM, Roy C, Schlesinger L, Seder R, Silver R, et al. Developing aerosol vaccines for Mycobacterium tuberculosis: Workshop proceedings. National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA, April 9, 2014. Vaccine. 33: 3038-3046. DOI: 10.1016/j.vaccine.2015.03.060  1
2014 Mortensen NP, Hickey AJ. Targeting inhaled therapy beyond the lungs. Respiration; International Review of Thoracic Diseases. 88: 353-4. PMID 25277464 DOI: 10.1159/000367852  1
2014 Mortensen NP, Durham P, Hickey AJ. The role of particle physico-chemical properties in pulmonary drug delivery for tuberculosis therapy. Journal of Microencapsulation. 31: 785-95. PMID 25090595 DOI: 10.3109/02652048.2014.932029  1
2014 Telko MJ, Hickey AJ. Aerodynamic and electrostatic properties of model dry powder aerosols: a comprehensive study of formulation factors. Aaps Pharmscitech. 15: 1378-97. PMID 24938617 DOI: 10.1208/s12249-014-0144-5  1
2014 Sayes CM, Staats H, Hickey AJ. Scale of health: indices of safety and efficacy in the evolving environment of large biological datasets. Pharmaceutical Research. 31: 2256-65. PMID 24919930 DOI: 10.1007/s11095-014-1415-2  1
2014 Hickey AJ. Controlled delivery of inhaled therapeutic agents. Journal of Controlled Release : Official Journal of the Controlled Release Society. 190: 182-8. PMID 24907604 DOI: 10.1016/j.jconrel.2014.05.058  1
2014 Cipolla D, Shekunov B, Blanchard J, Hickey A. Lipid-based carriers for pulmonary products: preclinical development and case studies in humans. Advanced Drug Delivery Reviews. 75: 53-80. PMID 24819218 DOI: 10.1016/j.addr.2014.05.001  1
2014 Grasmeijer F, Lexmond AJ, van den Noort M, Hagedoorn P, Hickey AJ, Frijlink HW, de Boer AH. New mechanisms to explain the effects of added lactose fines on the dispersion performance of adhesive mixtures for inhalation. Plos One. 9: e87825. PMID 24489969 DOI: 10.1371/journal.pone.0087825  1
2014 Hanif SNM, Hickey AJ, Garcia-Contreras L. Liquid chromatographic determination of CPZEN-45, a novel anti-tubercular drug, in biological samples Journal of Pharmaceutical and Biomedical Analysis. 88: 370-376. PMID 24176740 DOI: 10.1016/j.jpba.2013.09.014  1
2014 Hickey AJ, Holt J. Surface interactions in propellant driven metered dose inhaler product design Colloid and Interface Science in Pharmaceutical Research and Development. 79-102. DOI: 10.1016/B978-0-444-62614-1.00004-1  1
2014 Hickey AJ, Staats H, Roy CJ, Powell KG, Sullivan V, Rothrock G, Sayes CM. Nasal dry powder vaccine delivery technology Molecular Vaccines: From Prophylaxis to Therapy - Volume 2. 717-726. DOI: 10.1007/978-3-319-00978-0_18  1
2013 Hickey AJ, Misra A, Fourie PB. Dry powder antibiotic aerosol product development: inhaled therapy for tuberculosis. Journal of Pharmaceutical Sciences. 102: 3900-7. PMID 23963705 DOI: 10.1002/jps.23705  1
2013 Salomon JJ, Galeron P, Schulte N, Morow PR, Severynse-Stevens D, Huwer H, Daum N, Lehr CM, Hickey AJ, Ehrhardt C. Biopharmaceutical in vitro characterization of CPZEN-45, a drug candidate for inhalation therapy of tuberculosis. Therapeutic Delivery. 4: 915-23. PMID 23919471 DOI: 10.4155/tde.13.62  1
2013 Dharmadhikari AS, Kabadi M, Gerety B, Hickey AJ, Fourie PB, Nardell E. Phase I, single-dose, dose-escalating study of inhaled dry powder capreomycin: a new approach to therapy of drug-resistant tuberculosis. Antimicrobial Agents and Chemotherapy. 57: 2613-9. PMID 23529740 DOI: 10.1128/AAC.02346-12  1
2013 Apiou-Sbirlea G, Newman S, Fleming J, Siekmeier R, Ehrmann S, Scheuch G, Hochhaus G, Hickey A. Bioequivalence of inhaled drugs: fundamentals, challenges and perspectives. Therapeutic Delivery. 4: 343-67. PMID 23442081 DOI: 10.4155/tde.12.161  1
2013 Hickey AJ. Back to the future: inhaled drug products. Journal of Pharmaceutical Sciences. 102: 1165-72. PMID 23381932 DOI: 10.1002/jps.23465  1
2013 Fallon JK, Peyron ID, Hickey AJ. Effects of direct spiking of silicone oil into a model pMDI formulation. Drug Development and Industrial Pharmacy. 39: 681-6. PMID 22630349 DOI: 10.3109/03639045.2012.687380  1
2013 Hickey AJ, Mitchell J, Curry P, Suggett J, Poochikian G, Destefano AJ, Shah VP, Zaidi K. Responses to public comments about the introduction of general chapter Inhalation and Nasal Drug Products-General Information and Product Quality Tests <5> and revisions to general chapter Aerosols, Nasal Sprays, Metered-Dose Inhalers, and Dry Powder Inhalers <601> Pharmacopeial Forum. 39.  1
2012 Delong RK, Risor A, Kanomata M, Laymon A, Jones B, Zimmerman SD, Williams J, Witkowski C, Warner M, Ruff M, Garrad R, Fallon JK, Hickey AJ, Sedaghat-Herati R. Characterization of biomolecular nanoconjugates by high-throughput delivery and spectroscopic difference. Nanomedicine (London, England). 7: 1851-62. PMID 22943129 DOI: 10.2217/nnm.12.70  1
2012 Adams WP, Lee SL, Plourde R, Lionberger RA, Bertha CM, Doub WH, Bovet JM, Hickey AJ. Effects of device and formulation on in vitro performance of dry powder inhalers. The Aaps Journal. 14: 400-9. PMID 22476943 DOI: 10.1208/s12248-012-9352-7  1
2012 Garcia-Contreras L, Muttil P, Fallon JK, Kabadi M, Gerety R, Hickey AJ. Pharmacokinetics of sequential doses of capreomycin powder for inhalation in guinea pigs. Antimicrobial Agents and Chemotherapy. 56: 2612-8. PMID 22330920 DOI: 10.1128/AAC.06145-11  1
2012 Wang C, Garcia-Contreras L, Muttil P, Hickey AJ. Isoxyl assays in plasma. Journal of Pharmaceutical and Biomedical Analysis. 60: 1-6. PMID 22119164 DOI: 10.1016/j.jpba.2011.10.029  1
2012 Wang SH, Kirwan SM, Abraham SN, Staats HF, Hickey AJ. Stable dry powder formulation for nasal delivery of anthrax vaccine. Journal of Pharmaceutical Sciences. 101: 31-47. PMID 21905034 DOI: 10.1002/jps.22742  1
2012 Wang SH, Thompson AL, Hickey AJ, Staats HF. Dry powder vaccines for mucosal administration: critical factors in manufacture and delivery. Current Topics in Microbiology and Immunology. 354: 121-56. PMID 21822816 DOI: 10.1007/82_2011_167  1
2012 Xu Z, Hickey AJ. A comparison of aerosol performance using standardized entrainment tubes vs. dry powder inhaler devices Kona Powder and Particle Journal. 30: 201-210.  1
2011 Cooney DJ, Hickey AJ. Cellular response to the deposition of diesel exhaust particle aerosols onto human lung cells grown at the air-liquid interface by inertial impaction. Toxicology in Vitro : An International Journal Published in Association With Bibra. 25: 1953-65. PMID 21756993 DOI: 10.1016/j.tiv.2011.06.019  1
2011 Alexander BD, Winkler TP, Shi S, Dodds Ashley ES, Hickey AJ. In vitro characterization of nebulizer delivery of liposomal amphotericin B aerosols. Pharmaceutical Development and Technology. 16: 577-82. PMID 21699390 DOI: 10.3109/10837450.2011.591803  1
2011 Gibbons A, Padilla-Carlin D, Kelly C, Hickey AJ, Taggart C, McElvaney NG, Cryan SA. The effect of liposome encapsulation on the pharmacokinetics of recombinant secretory leukocyte protease inhibitor (rSLPI) therapy after local delivery to a guinea pig asthma model. Pharmaceutical Research. 28: 2233-45. PMID 21647791 DOI: 10.1007/s11095-011-0454-1  1
2011 Hickey AJ. Guinea pig model of infectious disease - viral infections. Current Drug Targets. 12: 1018-23. PMID 21366517  1
2011 Alexander BD, Winkler TP, Shi S, Ashley ES, Hickey AJ. Nebulizer delivery of micafungin aerosols. Pharmacotherapy. 31: 52-7. PMID 21182358 DOI: 10.1592/phco.31.1.52  1
2011 Hickey AJ, Misra A, Robertson BD. Optimisation of inhaled tuberculosis therapies and implications for host-pathogen interactions. Tuberculosis (Edinburgh, Scotland). 91: 64. PMID 21112251 DOI: 10.1016/j.tube.2010.10.002  1
2011 Misra A, Hickey AJ, Rossi C, Borchard G, Terada H, Makino K, Fourie PB, Colombo P. Inhaled drug therapy for treatment of tuberculosis. Tuberculosis (Edinburgh, Scotland). 91: 71-81. PMID 20875771 DOI: 10.1016/j.tube.2010.08.009  1
2011 Xu Z, Mansour HM, Hickey AJ. Particle interactions in dry powder inhaler unit processes: A review Journal of Adhesion Science and Technology. 25: 451-482. DOI: 10.1163/016942410X525669  1
2011 Hickey AJ, Swift D. Measurement of Pharmaceutical and Diagnostic Inhalation Aerosols Aerosol Measurement: Principles, Techniques, and Applications: Third Edition. 805-820. DOI: 10.1002/9781118001684.ch39  1
2011 Smyth HDC, Martonen TB, Isaacs KK, Hickey AJ. Estimation of particle deposition in the airways from different inhaler formulations using an in silico model Kona Powder and Particle Journal. 29: 107-117.  1
2011 Mitchell JP, Poochikian G, Hickey AJ, Suggett J, Curry PD, Tougas TP, Zaidi K. In vitro assessment of spacers and valved holding chambers used with pressurized metered-dose inhalers: The need for a USP chapter with clinically relevant test methods Pharmacopeial Forum. 37.  1
2010 Weers JG, Bell J, Chan HK, Cipolla D, Dunbar C, Hickey AJ, Smith IJ. Pulmonary formulations: what remains to be done? Journal of Aerosol Medicine and Pulmonary Drug Delivery. 23: S5-23. PMID 21133800 DOI: 10.1089/jamp.2010.0838  1
2010 Muttil P, Pulliam B, Garcia-Contreras L, Fallon JK, Wang C, Hickey AJ, Edwards DA. Pulmonary immunization of guinea pigs with diphtheria CRM-197 antigen as nanoparticle aggregate dry powders enhance local and systemic immune responses. The Aaps Journal. 12: 699-707. PMID 20878294 DOI: 10.1208/s12248-010-9229-6  1
2010 Gwinn WM, Kirwan SM, Wang SH, Ashcraft KA, Sparks NL, Doil CR, Tlusty TG, Casey LS, Hollingshead SK, Briles DE, Dondero RS, Hickey AJ, Foster WM, Staats HF. Effective induction of protective systemic immunity with nasally administered vaccines adjuvanted with IL-1. Vaccine. 28: 6901-14. PMID 20723629 DOI: 10.1016/j.vaccine.2010.08.006  1
2010 Wang C, Hickey AJ. Isoxyl particles for pulmonary delivery: In vitro cytotoxicity and potency. International Journal of Pharmaceutics. 396: 99-104. PMID 20600722 DOI: 10.1016/j.ijpharm.2010.06.037  1
2010 Lu D, Garcia-Contreras L, Muttil P, Padilla D, Xu D, Liu J, Braunstein M, McMurray DN, Hickey AJ. Pulmonary immunization using antigen 85-B polymeric microparticles to boost tuberculosis immunity. The Aaps Journal. 12: 338-47. PMID 20422340 DOI: 10.1208/s12248-010-9193-1  1
2010 Muttil P, Prego C, Garcia-Contreras L, Pulliam B, Fallon JK, Wang C, Hickey AJ, Edwards D. Immunization of guinea pigs with novel hepatitis B antigen as nanoparticle aggregate powders administered by the pulmonary route. The Aaps Journal. 12: 330-7. PMID 20419360 DOI: 10.1208/s12248-010-9192-2  1
2010 Wang C, Hickey AJ. Isoxyl aerosols for tuberculosis treatment: preparation and characterization of particles. Aaps Pharmscitech. 11: 538-49. PMID 20339959 DOI: 10.1208/s12249-010-9415-y  1
2010 Xu Z, Mansour HM, Mulder T, McLean R, Langridge J, Hickey AJ. Heterogeneous particle deaggregation and its implication for therapeutic aerosol performance. Journal of Pharmaceutical Sciences. 99: 3442-61. PMID 20232454 DOI: 10.1002/jps.22057  1
2010 Mansour HM, Xu Z, Hickey AJ. Dry powder aerosols generated by standardized entrainment tubes from alternative sugar blends: 3. Trehalose dihydrate and D-mannitol carriers. Journal of Pharmaceutical Sciences. 99: 3430-41. PMID 20229601 DOI: 10.1002/jps.22101  1
2010 Xu Z, Mansour HM, Mulder T, McLean R, Langridge J, Hickey AJ. Dry powder aerosols generated by standardized entrainment tubes from drug blends with lactose monohydrate: 2. Ipratropium bromide monohydrate and fluticasone propionate. Journal of Pharmaceutical Sciences. 99: 3415-29. PMID 20222025 DOI: 10.1002/jps.22100  1
2010 Xu Z, Mansour HM, Mulder T, McLean R, Langridge J, Hickey AJ. Dry powder aerosols generated by standardized entrainment tubes from drug blends with lactose monohydrate: 1. Albuterol sulfate and disodium cromoglycate. Journal of Pharmaceutical Sciences. 99: 3398-414. PMID 20198688 DOI: 10.1002/jps.22107  1
2010 Adams WP, Ahrens RC, Chen ML, Christopher D, Chowdhury BA, Conner DP, Dalby R, Fitzgerald K, Hendeles L, Hickey AJ, Hochhaus G, Laube BL, Lucas P, Lee SL, Lyapustina S, et al. Demonstrating Bioequivalence of Locally Acting Orally Inhaled Drug Products (OIPs): Workshop Summary Report. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 23: 1-29. PMID 20131983 DOI: 10.1089/jamp.2009.0803  1
2010 Garcia-Contreras L, Sung JC, Muttil P, Padilla D, Telko M, Verberkmoes JL, Elbert KJ, Hickey AJ, Edwards DA. Dry powder PA-824 aerosols for treatment of tuberculosis in guinea pigs. Antimicrobial Agents and Chemotherapy. 54: 1436-42. PMID 20086154 DOI: 10.1128/AAC.01471-09  1
2010 Shi S, Hickey AJ. PLGA microparticles in respirable sizes enhance an in vitro T cell response to recombinant Mycobacterium tuberculosis antigen TB10.4-Ag85B. Pharmaceutical Research. 27: 350-60. PMID 20024670 DOI: 10.1007/s11095-009-0028-7  1
2010 Shi S, Yu L, Sun D, Liu J, Hickey AJ. Rational design of multiple TB antigens TB10.4 and TB10.4-Ag85B as subunit vaccine candidates against Mycobacterium tuberculosis. Pharmaceutical Research. 27: 224-34. PMID 19862606 DOI: 10.1007/s11095-009-9995-y  1
2009 Muttil P, Wang C, Hickey AJ. Inhaled drug delivery for tuberculosis therapy. Pharmaceutical Research. 26: 2401-16. PMID 20183916 DOI: 10.1007/s11095-009-9957-4  1
2009 Shi S, Hickey AJ. Multivariate data analysis as a semi-quantitative tool for interpretive evaluation of comparability or equivalence of aerodynamic particle size distribution profiles. Aaps Pharmscitech. 10: 1113-20. PMID 19763839 DOI: 10.1208/s12249-009-9303-5  1
2009 DeLong RK, Akhtar U, Sallee M, Parker B, Barber S, Zhang J, Craig M, Garrad R, Hickey AJ, Engstrom E. Characterization and performance of nucleic acid nanoparticles combined with protamine and gold. Biomaterials. 30: 6451-9. PMID 19726081 DOI: 10.1016/j.biomaterials.2009.07.067  1
2009 Hickey AJ, Garmise RJ. Dry powder nasal vaccines as an alternative to needle-based delivery. Critical Reviews in Therapeutic Drug Carrier Systems. 26: 1-27. PMID 19496746  1
2009 Sung JC, Padilla DJ, Garcia-Contreras L, Verberkmoes JL, Durbin D, Peloquin CA, Elbert KJ, Hickey AJ, Edwards DA. Formulation and pharmacokinetics of self-assembled rifampicin nanoparticle systems for pulmonary delivery. Pharmaceutical Research. 26: 1847-55. PMID 19407933 DOI: 10.1007/s11095-009-9894-2  1
2009 Wang C, Muttil P, Lu D, Beltran-Torres AA, Garcia-Contreras L, Hickey AJ. Screening for potential adjuvants administered by the pulmonary route for tuberculosis vaccines. The Aaps Journal. 11: 139-47. PMID 19277872 DOI: 10.1208/s12248-009-9089-0  1
2009 Shi S, Ashley ES, Alexander BD, Hickey AJ. Initial characterization of micafungin pulmonary delivery via two different nebulizers and multivariate data analysis of aerosol mass distribution profiles. Aaps Pharmscitech. 10: 129-37. PMID 19189220 DOI: 10.1208/s12249-009-9185-6  1
2009 Sung JC, Garcia-Contreras L, Verberkmoes JL, Peloquin CA, Elbert KJ, Hickey AJ, Edwards DA. Dry powder nitroimidazopyran antibiotic PA-824 aerosol for inhalation. Antimicrobial Agents and Chemotherapy. 53: 1338-43. PMID 19139288 DOI: 10.1128/AAC.01389-08  1
2008 Cooney DJ, Hickey AJ. The generation of diesel exhaust particle aerosols from a bulk source in an aerodynamic size range similar to atmospheric particles. International Journal of Nanomedicine. 3: 435-49. PMID 19337412  1
2008 Padilla-Carlin DJ, McMurray DN, Hickey AJ. The guinea pig as a model of infectious diseases. Comparative Medicine. 58: 324-40. PMID 18724774  1
2008 Sivadas N, O'Rourke D, Tobin A, Buckley V, Ramtoola Z, Kelly JG, Hickey AJ, Cryan SA. A comparative study of a range of polymeric microspheres as potential carriers for the inhalation of proteins. International Journal of Pharmaceutics. 358: 159-67. PMID 18448288 DOI: 10.1016/j.ijpharm.2008.03.024  1
2008 Garcia-Contreras L, Wong YL, Muttil P, Padilla D, Sadoff J, Derousse J, Germishuizen WA, Goonesekera S, Elbert K, Bloom BR, Miller R, Fourie PB, Hickey A, Edwards D. Immunization by a bacterial aerosol. Proceedings of the National Academy of Sciences of the United States of America. 105: 4656-60. PMID 18344320 DOI: 10.1073/pnas.0800043105  1
2008 Garmise RJ, Hickey AJ. Calibration of the Andersen cascade impactor for the characterization of nasal products. Journal of Pharmaceutical Sciences. 97: 3462-6. PMID 18081008 DOI: 10.1002/jps.21267  1
2008 Fiegel J, Garcia-Contreras L, Thomas M, VerBerkmoes J, Elbert K, Hickey A, Edwards D. Preparation and in vivo evaluation of a dry powder for inhalation of capreomycin. Pharmaceutical Research. 25: 805-11. PMID 17657592 DOI: 10.1007/s11095-007-9381-6  1
2008 Gray VA, Hickey AJ, Balmer P, Davies NM, Dunbar C, Foster TS, Olsson BL, Sakagami M, Shah VP, Smurthwaite MJ, Veranth JM, Zaidi K. The Inhalation Ad Hoc Advisory Panel for the USP performance tests of inhalation dosage forms Pharmacopeial Forum. 34: 1068-1074.  1
2007 Mansour HM, Hickey AJ. Raman characterization and chemical imaging of biocolloidal self-assemblies, drug delivery systems, and pulmonary inhalation aerosols: a review. Aaps Pharmscitech. 8: E99. PMID 18181559 DOI: 10.1208/pt0804099  1
2007 Garmise RJ, Staats HF, Hickey AJ. Novel dry powder preparations of whole inactivated influenza virus for nasal vaccination. Aaps Pharmscitech. 8: E81. PMID 18181542 DOI: 10.1208/pt0804081  1
2007 Lu D, Garcia-Contreras L, Xu D, Kurtz SL, Liu J, Braunstein M, McMurray DN, Hickey AJ. Poly (lactide-co-glycolide) microspheres in respirable sizes enhance an in vitro T cell response to recombinant Mycobacterium tuberculosis antigen 85B. Pharmaceutical Research. 24: 1834-43. PMID 17657598 DOI: 10.1007/s11095-007-9302-8  1
2007 Telko MJ, Hickey AJ. Critical assessment of inverse gas chromatography as means of assessing surface free energy and acid-base interaction of pharmaceutical powders. Journal of Pharmaceutical Sciences. 96: 2647-54. PMID 17518355 DOI: 10.1002/jps.20897  1
2007 Garcia-Contreras L, Fiegel J, Telko MJ, Elbert K, Hawi A, Thomas M, VerBerkmoes J, Germishuizen WA, Fourie PB, Hickey AJ, Edwards D. Inhaled large porous particles of capreomycin for treatment of tuberculosis in a guinea pig model. Antimicrobial Agents and Chemotherapy. 51: 2830-6. PMID 17517845 DOI: 10.1128/AAC.01164-06  1
2007 Hickey AJ, Mansour HM, Telko MJ, Xu Z, Smyth HD, Mulder T, McLean R, Langridge J, Papadopoulos D. Physical characterization of component particles included in dry powder inhalers. II. Dynamic characteristics. Journal of Pharmaceutical Sciences. 96: 1302-19. PMID 17455364 DOI: 10.1002/jps.20943  1
2007 Hickey AJ, Mansour HM, Telko MJ, Xu Z, Smyth HD, Mulder T, McLean R, Langridge J, Papadopoulos D. Physical characterization of component particles included in dry powder inhalers. I. Strategy review and static characteristics. Journal of Pharmaceutical Sciences. 96: 1282-301. PMID 17455324 DOI: 10.1002/jps.20916  1
2007 Lu D, Hickey AJ. Pulmonary vaccine delivery. Expert Review of Vaccines. 6: 213-26. PMID 17408371 DOI: 10.1586/14760584.6.2.213  1
2007 Telko MJ, Kujanpää J, Hickey AJ. Investigation of triboelectric charging in dry powder inhalers using electrical low pressure impactor (ELPI). International Journal of Pharmaceutics. 336: 352-60. PMID 17218072 DOI: 10.1016/j.ijpharm.2006.12.018  1
2006 Garmise RJ, Mar K, Crowder TM, Hwang CR, Ferriter M, Huang J, Mikszta JA, Sullivan VJ, Hickey AJ. Formulation of a dry powder influenza vaccine for nasal delivery. Aaps Pharmscitech. 7: E131-E137. PMID 28290034 DOI: 10.1208/pt070119  0.92
2006 Smyth H, Hickey AJ, Brace G, Barbour T, Gallion J, Grove J. Spray pattern analysis for metered dose inhalers I: Orifice size, particle size, and droplet motion correlations. Drug Development and Industrial Pharmacy. 32: 1033-41. PMID 17012116 DOI: 10.1080/03639040600637598  1
2006 Garcia-Contreras L, Sethuraman V, Kazantseva M, Godfrey V, Hickey AJ. Evaluation of dosing regimen of respirable rifampicin biodegradable microspheres in the treatment of tuberculosis in the guinea pig Journal of Antimicrobial Chemotherapy. 58: 980-986. PMID 16971416 DOI: 10.1093/jac/dkl369  1
2006 Crowder T, Hickey A. Powder specific active dispersion for generation of pharmaceutical aerosols International Journal of Pharmaceutics. 327: 65-72. PMID 16930884 DOI: 10.1016/j.ijpharm.2006.07.050  1
2006 Taylor MK, Hickey AJ, VanOort M. Manufacture, characterization, and pharmacodynamic evaluation of engineered ipratropium bromide particles. Pharmaceutical Development and Technology. 11: 321-36. PMID 16895843 DOI: 10.1080/10837450600769637  1
2006 Smyth H, Brace G, Barbour T, Gallion J, Grove J, Hickey AJ. Spray pattern analysis for metered dose inhalers: effect of actuator design. Pharmaceutical Research. 23: 1591-6. PMID 16783475 DOI: 10.1007/s11095-006-0280-z  1
2006 Garmise RJ, Mar K, Crowder TM, Hwang CR, Ferriter M, Huang J, Mikszta JA, Sullivan VJ, Hickey AJ. Formulation of a dry powder influenza vaccine for nasal delivery. Aaps Pharmscitech. 7: E19. PMID 16584149 DOI: 10.1208/pt070119  1
2006 Cryan SA, Devocelle M, Moran PJ, Hickey AJ, Kelly JG. Increased intracellular targeting to airway cells using octaarginine-coated liposomes: in vitro assessment of their suitability for inhalation. Molecular Pharmaceutics. 3: 104-12. PMID 16579639 DOI: 10.1021/mp050070i  1
2006 Hickey AJ, Lu D, Ashley ED, Stout J. Inhaled azithromycin therapy. Journal of Aerosol Medicine : the Official Journal of the International Society For Aerosols in Medicine. 19: 54-60. PMID 16551215 DOI: 10.1089/jam.2006.19.54  1
2006 Louey MD, Van Oort M, Hickey AJ. Standardized entrainment tubes for the evaluation of pharmaceutical dry powder dispersion Journal of Aerosol Science. 37: 1520-1531. DOI: 10.1016/j.jaerosci.2006.04.002  1
2005 Lu D, Hickey AJ. Liposomal dry powders as aerosols for pulmonary delivery of proteins. Aaps Pharmscitech. 6: E641-8. PMID 16408866 DOI: 10.1208/pt060480  1
2005 Gopalakrishnan M, Suarez S, Hickey AJ, Gobburu JV. Population pharmacokinetic-pharmacodynamic modeling of subcutaneous and pulmonary insulin in rats. Journal of Pharmacokinetics and Pharmacodynamics. 32: 485-500. PMID 16284921 DOI: 10.1007/s10928-005-0008-4  1
2005 Telko MJ, Hickey AJ. Dry powder inhaler formulation. Respiratory Care. 50: 1209-27. PMID 16122404  1
2005 Smyth HDC, Hickey AJ. Carriers in drug powder delivery: Implications for inhalation system design American Journal of Drug Delivery. 3: 117-132. DOI: 10.2165/00137696-200503020-00004  1
2005 Hickey AJ. Pulmonary Drug Delivery: Pharmaceutical Chemistry and Aerosol Technology Drug Delivery: Principles and Applications. 341-361. DOI: 10.1002/0471475734.ch16  1
2005 Fiegel J, Garcia-Contreras L, Elbert K, Hickey A, Edwards D. Dry powder aerosols for multi-drug resistant tuberculosis (Mdr-Tb) treatment Aiche Annual Meeting, Conference Proceedings. 8568.  1
2004 Burgess DJ, Duffy E, Etzler F, Hickey AJ. Particle size analysis: AAPS workshop report, cosponsored by the Food and Drug Administration and the United States Pharmacopeia. The Aaps Journal. 6: e20. PMID 15760105 DOI: 10.1208/aapsj060320  1
2004 Cooney D, Kazantseva M, Hickey AJ. Development of a size-dependent aerosol deposition model utilising human airway epithelial cells for evaluating aerosol drug delivery. Alternatives to Laboratory Animals : Atla. 32: 581-90. PMID 15757496  1
2004 Tian Y, Klegerman ME, Hickey AJ. Evaluation of microparticles containing doxorubicin suitable for aerosol delivery to the lungs. Pda Journal of Pharmaceutical Science and Technology / Pda. 58: 266-75. PMID 15568648  1
2004 Huang J, Garmise RJ, Crowder TM, Mar K, Hwang CR, Hickey AJ, Mikszta JA, Sullivan VJ. A novel dry powder influenza vaccine and intranasal delivery technology: induction of systemic and mucosal immune responses in rats. Vaccine. 23: 794-801. PMID 15542204 DOI: 10.1016/j.vaccine.2004.06.049  1
2004 Pettis RJ, Knowles MR, Olivier KN, Kazantseva M, Hickey AJ. Ionic interaction of amiloride and uridine 5'-triphosphate in nebulizer solutions. Journal of Pharmaceutical Sciences. 93: 2399-406. PMID 15295799 DOI: 10.1002/jps.20142  1
2004 Louey MD, Van Oort M, Hickey AJ. Aerosol dispersion of respirable particles in narrow size distributions using drug-alone and lactose-blend formulations. Pharmaceutical Research. 21: 1207-13. PMID 15290861 DOI: 10.1023/B:PHAM.0000032991.74736.3e  1
2004 Louey MD, Van Oort M, Hickey AJ. Aerosol dispersion of respirable particles in narrow size distributions produced by jet-milling and spray-drying techniques. Pharmaceutical Research. 21: 1200-6. PMID 15290860 DOI: 10.1023/B:PHAM.0000033007.27278.60  1
2004 Smyth HD, Beck VP, Williams D, Hickey AJ. The influence of formulation and spacer device on the in vitro performance of solution chlorofluorocarbon-free propellant-driven metered dose inhalers. Aaps Pharmscitech. 5: E7. PMID 15198528 DOI: 10.1208/pt050107  1
2003 Sommerville ML, Hickey AJ. Aerosol generation by metered-dose inhalers containing dimethyl ether/propane inverse microemulsions. Aaps Pharmscitech. 4: E58. PMID 15198553 DOI: 10.1208/pt040458  1
2003 Garcia-Contreras L, Hickey AJ. Aerosol treatment of cystic fibrosis. Critical Reviews in Therapeutic Drug Carrier Systems. 20: 317-56. PMID 14959788 DOI: 10.1615/CritRevTherDrugCarrierSyst.v20.i5.10  1
2003 Smyth HD, Hickey AJ. Multimodal particle size distributions emitted from HFA-134a solution pressurized metered-dose inhalers. Aaps Pharmscitech. 4: E38. PMID 14621970 DOI: 10.1208/pt040338  1
2003 Cooney DJ, Hickey AJ. Preparation of disodium fluorescein powders in association with lauric and capric acids. Journal of Pharmaceutical Sciences. 92: 2341-4. PMID 14603518 DOI: 10.1002/jps.10488  1
2003 Garcia-Contreras L, Morçöl T, Bell SJ, Hickey AJ. Evaluation of novel particles as pulmonary delivery systems for insulin in rats. Aaps Pharmsci. 5: E9. PMID 12866936 DOI: 10.1208/ps050209  1
2003 Hickey AJ. Aerosol delivery and asthma therapy Advanced Drug Delivery Reviews. 55: 777. DOI: 10.1016/S0169-409X(03)00076-0  1
2003 Hickey AJ. Pharmaceutical inhalation aerosol powder dispersion - An unbalancing act American Pharmaceutical Review. 6: 106-110.  1
2002 Sethuraman VV, Hickey AJ. Powder properties and their influence on dry powder inhaler delivery of an antitubercular drug. Aaps Pharmscitech. 3: E28. PMID 12916922 DOI: 10.1208/pt030428  1
2002 Garcia-Contreras L, Hickey AJ. Pharmaceutical and biotechnological aerosols for cystic fibrosis therapy. Advanced Drug Delivery Reviews. 54: 1491-504. PMID 12458157 DOI: 10.1016/S0169-409X(02)00159-X  1
2002 Zhang Z, Kleinstreuer C, Kim CS, Hickey AJ. Aerosol transport and deposition in a triple bifurcation bronchial airway model with local tumors Inhalation Toxicology. 14: 1111-1133. PMID 12454794 DOI: 10.1080/08958370290084809  1
2002 Sommerville ML, Johnson CS, Cain JB, Rypacek F, Hickey AJ. Lecithin microemulsions in dimethyl ether and propane for the generation of pharmaceutical aerosols containing polar solutes. Pharmaceutical Development and Technology. 7: 273-88. PMID 12229259 DOI: 10.1081/PDT-120005724  1
2002 Musante CJ, Schroeter JD, Rosati JA, Crowder TM, Hickey AJ, Martonen TB. Factors affecting the deposition of inhaled porous drug particles. Journal of Pharmaceutical Sciences. 91: 1590-600. PMID 12115821 DOI: 10.1002/jps.10152  1
2002 Deaton AT, Jones LD, Dunbar CA, Hickey AJ, Williams DM. Generation of gelatin aerosol particles from nebulized solutions as model drug carrier systems. Pharmaceutical Development and Technology. 7: 147-53. PMID 12066570 DOI: 10.1081/PDT-120003483  1
2002 Crowder TM, Rosati JA, Schroeter JD, Hickey AJ, Martonen TB. Fundamental effects of particle morphology on lung delivery: predictions of Stokes' law and the particular relevance to dry powder inhaler formulation and development. Pharmaceutical Research. 19: 239-45. PMID 11934228 DOI: 10.1023/A:1014426530935  1
2001 Sethuraman VV, Hickey AJ. Evaluation of preseparator performance for the 8-stage nonviable andersen impactor. Aaps Pharmscitech. 2: E4. PMID 14727889 DOI: 10.1208/pt020104  1
2001 Garcia-Contreras L, Sarubbi D, Flanders E, O'Toole D, Smart J, Newcomer C, Hickey AJ. Immediate and short-term cellular and biochemical responses to pulmonary single-dose studies of insulin and H-MAP Pharmaceutical Research. 18: 1685-1693. PMID 11785687 DOI: 10.1023/A:1013314311619  1
2001 Suarez S, Garcia-Contreras L, Sarubbi D, Flanders E, O'Toole D, Smart J, Hickey AJ. Facilitation of pulmonary insulin absorption by H-MAP: Pharmacokinetics and pharmacodynamics in rats Pharmaceutical Research. 18: 1677-1684. PMID 11785686 DOI: 10.1023/A:1013362227548  1
2001 Suarez S, O'Hara P, Kazantseva M, Newcomer CE, Hopfer R, McMurray DN, Hickey AJ. Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis: Screening in an infectious disease model Pharmaceutical Research. 18: 1315-1319. PMID 11683246 DOI: 10.1023/A:1013094112861  1
2001 Hickey AJ, Garcia-Contreras L. Immunological and toxicological implications of short-term studies in animals of pharmaceutical aerosol delivery to the lungs: Relevance to humans Critical Reviews in Therapeutic Drug Carrier Systems. 18: 387-431. PMID 11605897  1
2001 Suarez S, O'Hara P, Kazantseva M, Newcomer CE, Hopfer R, McMurray DN, Hickey AJ. Airways delivery of rifampicin microparticles for the treatment of tuberculosis Journal of Antimicrobial Chemotherapy. 48: 431-434. PMID 11533012  1
2001 Suarez S, Kazantseva M, Bhat M, Costa D, Hickey AJ. The influence of suspension nebulization or instillation on particle uptake by guinea pig alveolar macrophages Inhalation Toxicology. 13: 773-788. PMID 11498805  1
2001 Sethuraman VV, Hickey AJ. Evaluation preseparator performance for the 8-stage nonviable Andersen impactor Aaps Pharmscitech. 2.  1
2001 Crowder TM, Louey MD, Sethuraman VV, Smyth HDC, Hickey AJ. 2001: An odyssey in inhaler formulation and design Pharmaceutical Technology. 25: 99-113.  1
2000 Pettis RJ, Hall I, Costa D, Hickey AJ. Aerosol delivery of muramyl dipeptide to rodent lungs Aaps Pharmsci [Electronic Resource]. 2: E25. PMID 11741241 DOI: 10.1208/ps020325  1
2000 Dunbar CA, Morgan B, Van Oort M, Hickey AJ. A comparison of dry powder inhaler dose delivery characteristics using a power criterion Pda Journal of Pharmaceutical Science and Technology. 54: 478-484. PMID 11107840  1
2000 O'Hara P, Hickey AJ. Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis: Manufacture and characterization Pharmaceutical Research. 17: 955-961. PMID 11028941 DOI: 10.1023/A:1007527204887  1
2000 Suarez S, Hickey AJ. Drug properties affecting aerosol behavior Respiratory Care. 45: 652-666. PMID 10894458  1
2000 Sommerville ML, Cain JB, Johnson CS, Hickey AJ. Lecithin inverse microemulsions for the pulmonary delivery of polar compounds utilizing dimethylether and propane as propellants. Pharmaceutical Development and Technology. 5: 219-30. PMID 10810752 DOI: 10.1081/PDT-100100537  1
2000 Bhat M, Hickey AJ. Effect of chloroquine on phagolysosomal fusion in cultured guinea pig alveolar macrophages: Implications in drug delivery Aaps Pharmsci. 2: 1-7. DOI: 10.1208/ps020434  1
2000 Dunbar CA, Hickey AJ. Evaluation of probability density functions to approximate particle size distributions of representative pharmaceutical aerosols Journal of Aerosol Science. 31: 813-831. DOI: 10.1016/S0021-8502(99)00557-1  1
2000 Taylor MK, Ginsburg J, Hickey AJ, Gheyas F. Composite method to quantify powder flow as a screening method in early tablet or capsule formulation development Aaps Pharmscitech. 1.  1
2000 Dolovich MB, Macintyre NR, Anderson PJ, Camargo JA, Chew N, Cole CH, Dhand R, Fink JB, Gross NJ, Hess DR, Hickey AJ, Kim CS, Martonen TB, Pierson DJ, Rubin BK, et al. Consensus statement: Aerosols and delivery devices Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung. 13: 291-300.  1
2000 Dolovich MB, Macintyre NR, Anderson PJ, Camargo JA, Chew N, Cole CH, Dhand R, Fink JB, Gross NJ, Hess DR, Hickey AJ, Kim CS, Martonen TB, Pierson DJ, Rubin BK, et al. Consensus statement: Aerosols and delivery devices Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung. 13: 291-300.  1
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