Anthony J. Hickey - Publications

Affiliations: 
Biomedical Engineering Joint Program University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Biomedical

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Maloney SE, Stewart IE, Mecham JB, Gonzalez-Juarrero M, Meibohm B, Hickey AJ. Disposable Dosators Intended for Dry Powder Delivery to Mice. Journal of Visualized Experiments : Jove. PMID 37607097 DOI: 10.3791/65756  0.309
2023 Maloney SE, Alshiraihi IM, Singh A, Stewart IE, Mariner Gonzalez J, Gonzalez-Juarrero M, Meibohm B, Hickey AJ. Spray dried tigecycline dry powder aerosols for the treatment of Nontuberculous mycobacterial pulmonary infections. Tuberculosis (Edinburgh, Scotland). 139: 102306. PMID 36716525 DOI: 10.1016/j.tube.2023.102306  0.306
2021 Garcia-Contreras L, Sethuraman V, Kazantseva M, Hickey A. Efficacy of Combined Rifampicin Formulations Delivered by the Pulmonary Route to Treat Tuberculosis in the Guinea Pig Model. Pharmaceutics. 13. PMID 34452270 DOI: 10.3390/pharmaceutics13081309  0.603
2020 Edwards D, Hickey A, Batycky R, Griel L, Lipp M, Dehaan W, Clarke R, Hava D, Perry J, Laurenzi B, Curran AK, Beddingfield BJ, Roy CJ, Devlin T, Langer R. A New Natural Defense Against Airborne Pathogens. Qrb Discovery. 1: e5. PMID 34192261 DOI: 10.1017/qrd.2020.9  0.307
2020 Hickey AJ. Emerging trends in inhaled drug delivery. Advanced Drug Delivery Reviews. PMID 32663488 DOI: 10.1016/J.Addr.2020.07.006  0.362
2019 Braunstein M, Hickey AJ, Ekins S. Why Wait? The Case for Treating Tuberculosis with Inhaled Drugs. Pharmaceutical Research. 36: 166. PMID 31650321 DOI: 10.1007/S11095-019-2704-6  0.327
2019 Walz A, Lukka PB, Pearce C, Creissen E, Braunstein M, Hickey AJ, Meibohm B, Gonzalez-Juarrero M. Sterilization of Mycobacterium tuberculosis infected samples using methanol preserves anti-tuberculosis drugs for subsequent pharmacological testing studies. Tuberculosis (Edinburgh, Scotland). 117: 52-55. PMID 31378268 DOI: 10.1016/J.Tube.2019.06.002  0.3
2019 Pitner RA, Durham PG, Stewart IE, Reed SG, Cassell GH, Hickey AJ, Carter D. A Spray-dried combination of capreomycin and cpzen-45 for inhaled tuberculosis therapy. Journal of Pharmaceutical Sciences. PMID 31152746 DOI: 10.1016/J.Xphs.2019.05.024  0.449
2019 Rathi C, Lukka PB, Wagh S, Lee RE, Lenaerts AJ, Braunstein M, Hickey A, Gonzalez-Juarrero M, Meibohm B. Comparative pharmacokinetics of spectinamide 1599 after subcutaneous and intrapulmonary aerosol administration in mice. Tuberculosis (Edinburgh, Scotland). 114: 119-122. PMID 30711150 DOI: 10.1016/J.Tube.2018.12.006  0.343
2018 Montgomery SA, Young EF, Durham PG, Zulauf KE, Rank L, Miller BK, Hayden JD, Lin FC, Welch JT, Hickey AJ, Braunstein M. Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis. Plos One. 13: e0204495. PMID 30261007 DOI: 10.1371/Journal.Pone.0204495  0.316
2018 Santos K, Lukka PB, Grzegorzewicz A, Jackson M, Trivedi A, Pavan F, Chorilli M, Braunstein M, Hickey A, Meibohm B, Gonzalez-Juarrero M. Primary Lung Dendritic Cell Cultures to Assess Efficacy of Spectinamide-1599 Against Intracellular . Frontiers in Microbiology. 9: 1895. PMID 30186246 DOI: 10.3389/Fmicb.2018.01895  0.326
2018 Kukut Hatipoglu M, Hickey AJ, Garcia-Contreras L. Pharmacokinetics and pharmacodynamics of high doses of inhaled dry powder drugs. International Journal of Pharmaceutics. 549: 306-316. PMID 30077761 DOI: 10.1016/J.Ijpharm.2018.07.050  0.441
2018 Schroeter JD, Sheth P, Hickey AJ, Asgharian B, Price OT, Holt JT, Conti DS, Saluja B. Effects of Formulation Variables on Lung Dosimetry of Albuterol Sulfate Suspension and Beclomethasone Dipropionate Solution Metered Dose Inhalers. Aaps Pharmscitech. PMID 29858973 DOI: 10.1208/S12249-018-1071-7  0.407
2018 Ferguson GT, Hickey AJ, Dwivedi S. Co-suspension delivery technology in pressurized metered-dose inhalers for multi-drug dosing in the treatment of respiratory diseases. Respiratory Medicine. 134: 16-23. PMID 29413503 DOI: 10.1016/J.Rmed.2017.09.012  0.369
2017 Hickey AJ, Edwards DA. Density and Shape Factor Terms in Stokes' Equation for Aerodynamic Behavior of Aerosols. Journal of Pharmaceutical Sciences. PMID 29154770 DOI: 10.1016/J.Xphs.2017.11.005  0.431
2017 Sheth P, Sandell D, Conti DS, Holt JT, Hickey AJ, Saluja B. Influence of Formulation Factors on the Aerosol Performance of Suspension and Solution Metered Dose Inhalers: A Systematic Approach. The Aaps Journal. PMID 28593514 DOI: 10.1208/S12248-017-0095-3  0.42
2017 Durham PG, Hanif SN, Contreras LG, Young EF, Braunstein MS, Hickey AJ. Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals. Journal of Visualized Experiments : Jove. PMID 28447980 DOI: 10.3791/55356  0.454
2016 Garcia-Contreras L, Padilla-Carlin DJ, Sung J, VerBerkmoes J, Muttil P, Elbert K, Peloquin C, Edwards D, Hickey A. Pharmacokinetics of Ethionamide Delivered in Spray-Dried Microparticles to the Lungs of Guinea Pigs. Journal of Pharmaceutical Sciences. PMID 27842973 DOI: 10.1016/J.Xphs.2016.09.033  0.446
2016 Sayes CM, Aquino GV, Hickey AJ. Nanomaterial Drug Products: Manufacturing and Analytical Perspectives. The Aaps Journal. PMID 27822601 DOI: 10.1208/S12248-016-0008-X  0.315
2016 Young EF, Perkowski E, Malik S, Hayden JD, Durham PG, Zhong L, Welch JT, Braunstein MS, Hickey AJ. Inhaled Pyrazinoic Acid Esters for the Treatment of Tuberculosis. Pharmaceutical Research. PMID 27351427 DOI: 10.1007/S11095-016-1974-5  0.304
2016 Durham PG, Young EF, Braunstein MS, Welch JT, Hickey AJ. A dry powder combination of pyrazinoic acid and its n-propyl ester for aerosol administration to animals. International Journal of Pharmaceutics. PMID 27130363 DOI: 10.1016/J.Ijpharm.2016.04.063  0.487
2016 Wood R, Morrow C, Barry CE, Bryden WA, Call CJ, Hickey AJ, Rodes CE, Scriba TJ, Blackburn J, Issarow C, Mulder N, Woodward J, Moosa A, Singh V, Mizrahi V, et al. Real-Time Investigation of Tuberculosis Transmission: Developing the Respiratory Aerosol Sampling Chamber (RASC). Plos One. 11: e0146658. PMID 26807816 DOI: 10.1371/Journal.Pone.0146658  0.371
2016 Hastedt JE, Bäckman P, Clark AR, Doub W, Hickey A, Hochhaus G, Kuehl PJ, Lehr C, Mauser P, McConville J, Niven R, Sakagimi M, Weers JG. Scope and relevance of a pulmonary biopharmaceutical classification system AAPS/FDA/USP Workshop March 16-17th, 2015 in Baltimore, MD Aaps Open. 2. DOI: 10.1186/S41120-015-0002-X  0.39
2016 Hickey AJ. Pulmonary Drug Delivery The Biomedical & Life Sciences Collection. 186-206. DOI: 10.1002/9781118833322.Ch10  0.326
2015 Hickey AJ, Durham PG, Dharmadhikari A, Nardell EA. Inhaled drug treatment for tuberculosis: Past progress and future prospects. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26596254 DOI: 10.1016/J.Jconrel.2015.11.018  0.335
2015 Durham PG, Zhang Y, German N, Mortensen N, Dhillon J, Mitchison DA, Fourie PB, Hickey AJ. Correction for Spray Dried Aerosol Particles of Pyrazinoic Acid Salts for Tuberculosis Therapy. Molecular Pharmaceutics. 12: 3782. PMID 26394135 DOI: 10.1021/Acs.Molpharmaceut.5B00673  0.396
2015 Durham PG, Zhang Y, German N, Mortensen N, Dhillon J, Mitchison DA, Fourie PB, Hickey AJ. Spray Dried Aerosol Particles of Salts for Tuberculosis Therapy. Molecular Pharmaceutics. PMID 26098136 DOI: 10.1021/Acs.Molpharmaceut.5B00118  0.481
2015 Garcia Contreras L, Sung J, Ibrahim M, Elbert K, Edwards D, Hickey A. Pharmacokinetics of Inhaled Rifampicin Porous Particles for Tuberculosis Treatment: Insight into Rifampicin Absorption from the Lungs of Guinea Pigs. Molecular Pharmaceutics. 12: 2642-50. PMID 25942002 DOI: 10.1021/Acs.Molpharmaceut.5B00046  0.435
2015 Ziffels S, Bemelmans NL, Durham PG, Hickey AJ. In vitro dry powder inhaler formulation performance considerations. Journal of Controlled Release : Official Journal of the Controlled Release Society. 199: 45-52. PMID 25497311 DOI: 10.1016/J.Jconrel.2014.11.035  0.443
2015 Garcia Contreras L, Sung J, Ibrahim M, Elbert K, Edwards D, Hickey A. Pharmacokinetics of Inhaled Rifampicin Porous Particles for Tuberculosis Treatment: Insight into Rifampicin Absorption from the Lungs of Guinea Pigs Molecular Pharmaceutics. 12: 2642-2650. DOI: 10.1021/acs.molpharmaceut.5b00046  0.31
2015 Achkar J, Beverley P, Boom H, Evans T, Hanekom W, Hickey A, Hoft D, Lakhani D, Lin PL, Ramanathan R, Henao-Restrepo AM, Roy C, Schlesinger L, Seder R, Silver R, et al. Developing aerosol vaccines for Mycobacterium tuberculosis: Workshop proceedings. National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA, April 9, 2014. Vaccine. 33: 3038-3046. DOI: 10.1016/J.Vaccine.2015.03.060  0.303
2014 Mortensen NP, Hickey AJ. Targeting inhaled therapy beyond the lungs. Respiration; International Review of Thoracic Diseases. 88: 353-4. PMID 25277464 DOI: 10.1159/000367852  0.368
2014 Mortensen NP, Durham P, Hickey AJ. The role of particle physico-chemical properties in pulmonary drug delivery for tuberculosis therapy. Journal of Microencapsulation. 31: 785-95. PMID 25090595 DOI: 10.3109/02652048.2014.932029  0.466
2014 Telko MJ, Hickey AJ. Aerodynamic and electrostatic properties of model dry powder aerosols: a comprehensive study of formulation factors. Aaps Pharmscitech. 15: 1378-97. PMID 24938617 DOI: 10.1208/S12249-014-0144-5  0.814
2014 Hickey AJ. Controlled delivery of inhaled therapeutic agents. Journal of Controlled Release : Official Journal of the Controlled Release Society. 190: 182-8. PMID 24907604 DOI: 10.1016/J.Jconrel.2014.05.058  0.363
2014 Cipolla D, Shekunov B, Blanchard J, Hickey A. Lipid-based carriers for pulmonary products: preclinical development and case studies in humans. Advanced Drug Delivery Reviews. 75: 53-80. PMID 24819218 DOI: 10.1016/J.Addr.2014.05.001  0.339
2014 Grasmeijer F, Lexmond AJ, van den Noort M, Hagedoorn P, Hickey AJ, Frijlink HW, de Boer AH. New mechanisms to explain the effects of added lactose fines on the dispersion performance of adhesive mixtures for inhalation. Plos One. 9: e87825. PMID 24489969 DOI: 10.1371/Journal.Pone.0087825  0.435
2014 Hanif SNM, Hickey AJ, Garcia-Contreras L. Liquid chromatographic determination of CPZEN-45, a novel anti-tubercular drug, in biological samples Journal of Pharmaceutical and Biomedical Analysis. 88: 370-376. PMID 24176740 DOI: 10.1016/J.Jpba.2013.09.014  0.309
2013 Hickey AJ, Misra A, Fourie PB. Dry powder antibiotic aerosol product development: inhaled therapy for tuberculosis. Journal of Pharmaceutical Sciences. 102: 3900-7. PMID 23963705 DOI: 10.1002/Jps.23705  0.323
2013 Salomon JJ, Galeron P, Schulte N, Morow PR, Severynse-Stevens D, Huwer H, Daum N, Lehr CM, Hickey AJ, Ehrhardt C. Biopharmaceutical in vitro characterization of CPZEN-45, a drug candidate for inhalation therapy of tuberculosis. Therapeutic Delivery. 4: 915-23. PMID 23919471 DOI: 10.4155/Tde.13.62  0.308
2013 Dharmadhikari AS, Kabadi M, Gerety B, Hickey AJ, Fourie PB, Nardell E. Phase I, single-dose, dose-escalating study of inhaled dry powder capreomycin: a new approach to therapy of drug-resistant tuberculosis. Antimicrobial Agents and Chemotherapy. 57: 2613-9. PMID 23529740 DOI: 10.1128/Aac.02346-12  0.338
2013 Apiou-Sbirlea G, Newman S, Fleming J, Siekmeier R, Ehrmann S, Scheuch G, Hochhaus G, Hickey A. Bioequivalence of inhaled drugs: fundamentals, challenges and perspectives. Therapeutic Delivery. 4: 343-67. PMID 23442081 DOI: 10.4155/Tde.12.161  0.332
2013 Hickey AJ. Back to the future: inhaled drug products. Journal of Pharmaceutical Sciences. 102: 1165-72. PMID 23381932 DOI: 10.1002/Jps.23465  0.352
2013 Fallon JK, Peyron ID, Hickey AJ. Effects of direct spiking of silicone oil into a model pMDI formulation. Drug Development and Industrial Pharmacy. 39: 681-6. PMID 22630349 DOI: 10.3109/03639045.2012.687380  0.335
2012 Adams WP, Lee SL, Plourde R, Lionberger RA, Bertha CM, Doub WH, Bovet JM, Hickey AJ. Effects of device and formulation on in vitro performance of dry powder inhalers. The Aaps Journal. 14: 400-9. PMID 22476943 DOI: 10.1208/S12248-012-9352-7  0.322
2012 Garcia-Contreras L, Muttil P, Fallon JK, Kabadi M, Gerety R, Hickey AJ. Pharmacokinetics of sequential doses of capreomycin powder for inhalation in guinea pigs. Antimicrobial Agents and Chemotherapy. 56: 2612-8. PMID 22330920 DOI: 10.1128/Aac.06145-11  0.364
2012 Wang SH, Kirwan SM, Abraham SN, Staats HF, Hickey AJ. Stable dry powder formulation for nasal delivery of anthrax vaccine. Journal of Pharmaceutical Sciences. 101: 31-47. PMID 21905034 DOI: 10.1002/Jps.22742  0.583
2012 Wang SH, Thompson AL, Hickey AJ, Staats HF. Dry powder vaccines for mucosal administration: critical factors in manufacture and delivery. Current Topics in Microbiology and Immunology. 354: 121-56. PMID 21822816 DOI: 10.1007/82_2011_167  0.553
2011 Cooney DJ, Hickey AJ. Cellular response to the deposition of diesel exhaust particle aerosols onto human lung cells grown at the air-liquid interface by inertial impaction. Toxicology in Vitro : An International Journal Published in Association With Bibra. 25: 1953-65. PMID 21756993 DOI: 10.1016/J.Tiv.2011.06.019  0.797
2011 Alexander BD, Winkler TP, Shi S, Dodds Ashley ES, Hickey AJ. In vitro characterization of nebulizer delivery of liposomal amphotericin B aerosols. Pharmaceutical Development and Technology. 16: 577-82. PMID 21699390 DOI: 10.3109/10837450.2011.591803  0.567
2011 Alexander BD, Winkler TP, Shi S, Ashley ES, Hickey AJ. Nebulizer delivery of micafungin aerosols. Pharmacotherapy. 31: 52-7. PMID 21182358 DOI: 10.1592/Phco.31.1.52  0.56
2011 Misra A, Hickey AJ, Rossi C, Borchard G, Terada H, Makino K, Fourie PB, Colombo P. Inhaled drug therapy for treatment of tuberculosis. Tuberculosis (Edinburgh, Scotland). 91: 71-81. PMID 20875771 DOI: 10.1016/J.Tube.2010.08.009  0.377
2011 Smyth HDC, Martonen TB, Isaacs KK, Hickey AJ. Estimation of particle deposition in the airways from different inhaler formulations using an in silico model Kona Powder and Particle Journal. 29: 107-117. DOI: 10.14356/Kona.2011013  0.383
2011 Xu Z, Mansour HM, Hickey AJ. Particle interactions in dry powder inhaler unit processes: A review Journal of Adhesion Science and Technology. 25: 451-482. DOI: 10.1163/016942410X525669  0.459
2011 Gwinn WM, Kirwan SM, Wang SH, Ashcraft KA, Sparks NL, Doil CR, Tlusty TG, Casey LS, Hollingshead SK, Briles DE, Dondero RS, Hickey AJ, Foster WM, Staats HF. Erratum to “Effective induction of protective systemic immunity with nasally administered vaccines adjuvanted with IL-1” [Vaccine 28 (42) (2010) 6901–6914] Vaccine. 29: 2821. DOI: 10.1016/J.Vaccine.2011.01.096  0.493
2010 Weers JG, Bell J, Chan HK, Cipolla D, Dunbar C, Hickey AJ, Smith IJ. Pulmonary formulations: what remains to be done? Journal of Aerosol Medicine and Pulmonary Drug Delivery. 23: S5-23. PMID 21133800 DOI: 10.1089/Jamp.2010.0838  0.428
2010 Muttil P, Pulliam B, Garcia-Contreras L, Fallon JK, Wang C, Hickey AJ, Edwards DA. Pulmonary immunization of guinea pigs with diphtheria CRM-197 antigen as nanoparticle aggregate dry powders enhance local and systemic immune responses. The Aaps Journal. 12: 699-707. PMID 20878294 DOI: 10.1208/S12248-010-9229-6  0.359
2010 Gwinn WM, Kirwan SM, Wang SH, Ashcraft KA, Sparks NL, Doil CR, Tlusty TG, Casey LS, Hollingshead SK, Briles DE, Dondero RS, Hickey AJ, Foster WM, Staats HF. Effective induction of protective systemic immunity with nasally administered vaccines adjuvanted with IL-1. Vaccine. 28: 6901-14. PMID 20723629 DOI: 10.1016/J.Vaccine.2010.08.006  0.522
2010 Wang C, Hickey AJ. Isoxyl particles for pulmonary delivery: In vitro cytotoxicity and potency. International Journal of Pharmaceutics. 396: 99-104. PMID 20600722 DOI: 10.1016/J.Ijpharm.2010.06.037  0.395
2010 Lu D, Garcia-Contreras L, Muttil P, Padilla D, Xu D, Liu J, Braunstein M, McMurray DN, Hickey AJ. Pulmonary immunization using antigen 85-B polymeric microparticles to boost tuberculosis immunity. The Aaps Journal. 12: 338-47. PMID 20422340 DOI: 10.1208/S12248-010-9193-1  0.568
2010 Muttil P, Prego C, Garcia-Contreras L, Pulliam B, Fallon JK, Wang C, Hickey AJ, Edwards D. Immunization of guinea pigs with novel hepatitis B antigen as nanoparticle aggregate powders administered by the pulmonary route. The Aaps Journal. 12: 330-7. PMID 20419360 DOI: 10.1208/S12248-010-9192-2  0.314
2010 Wang C, Hickey AJ. Isoxyl aerosols for tuberculosis treatment: preparation and characterization of particles. Aaps Pharmscitech. 11: 538-49. PMID 20339959 DOI: 10.1208/S12249-010-9415-Y  0.432
2010 Xu Z, Mansour HM, Mulder T, McLean R, Langridge J, Hickey AJ. Heterogeneous particle deaggregation and its implication for therapeutic aerosol performance. Journal of Pharmaceutical Sciences. 99: 3442-61. PMID 20232454 DOI: 10.1002/Jps.22057  0.435
2010 Mansour HM, Xu Z, Hickey AJ. Dry powder aerosols generated by standardized entrainment tubes from alternative sugar blends: 3. Trehalose dihydrate and D-mannitol carriers. Journal of Pharmaceutical Sciences. 99: 3430-41. PMID 20229601 DOI: 10.1002/Jps.22101  0.428
2010 Xu Z, Mansour HM, Mulder T, McLean R, Langridge J, Hickey AJ. Dry powder aerosols generated by standardized entrainment tubes from drug blends with lactose monohydrate: 2. Ipratropium bromide monohydrate and fluticasone propionate. Journal of Pharmaceutical Sciences. 99: 3415-29. PMID 20222025 DOI: 10.1002/Jps.22100  0.341
2010 Xu Z, Mansour HM, Mulder T, McLean R, Langridge J, Hickey AJ. Dry powder aerosols generated by standardized entrainment tubes from drug blends with lactose monohydrate: 1. Albuterol sulfate and disodium cromoglycate. Journal of Pharmaceutical Sciences. 99: 3398-414. PMID 20198688 DOI: 10.1002/Jps.22107  0.459
2010 Adams WP, Ahrens RC, Chen ML, Christopher D, Chowdhury BA, Conner DP, Dalby R, Fitzgerald K, Hendeles L, Hickey AJ, Hochhaus G, Laube BL, Lucas P, Lee SL, Lyapustina S, et al. Demonstrating Bioequivalence of Locally Acting Orally Inhaled Drug Products (OIPs): Workshop Summary Report. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 23: 1-29. PMID 20131983 DOI: 10.1089/Jamp.2009.0803  0.356
2010 Garcia-Contreras L, Sung JC, Muttil P, Padilla D, Telko M, Verberkmoes JL, Elbert KJ, Hickey AJ, Edwards DA. Dry powder PA-824 aerosols for treatment of tuberculosis in guinea pigs. Antimicrobial Agents and Chemotherapy. 54: 1436-42. PMID 20086154 DOI: 10.1128/Aac.01471-09  0.799
2010 Shi S, Hickey AJ. PLGA microparticles in respirable sizes enhance an in vitro T cell response to recombinant Mycobacterium tuberculosis antigen TB10.4-Ag85B. Pharmaceutical Research. 27: 350-60. PMID 20024670 DOI: 10.1007/S11095-009-0028-7  0.559
2010 Shi S, Yu L, Sun D, Liu J, Hickey AJ. Rational design of multiple TB antigens TB10.4 and TB10.4-Ag85B as subunit vaccine candidates against Mycobacterium tuberculosis. Pharmaceutical Research. 27: 224-34. PMID 19862606 DOI: 10.1007/S11095-009-9995-Y  0.485
2009 Muttil P, Wang C, Hickey AJ. Inhaled drug delivery for tuberculosis therapy. Pharmaceutical Research. 26: 2401-16. PMID 20183916 DOI: 10.1007/S11095-009-9957-4  0.326
2009 Shi S, Hickey AJ. Multivariate data analysis as a semi-quantitative tool for interpretive evaluation of comparability or equivalence of aerodynamic particle size distribution profiles. Aaps Pharmscitech. 10: 1113-20. PMID 19763839 DOI: 10.1208/S12249-009-9303-5  0.541
2009 Hickey AJ, Garmise RJ. Dry powder nasal vaccines as an alternative to needle-based delivery. Critical Reviews in Therapeutic Drug Carrier Systems. 26: 1-27. PMID 19496746 DOI: 10.1615/Critrevtherdrugcarriersyst.V26.I1.10  0.798
2009 Sung JC, Padilla DJ, Garcia-Contreras L, Verberkmoes JL, Durbin D, Peloquin CA, Elbert KJ, Hickey AJ, Edwards DA. Formulation and pharmacokinetics of self-assembled rifampicin nanoparticle systems for pulmonary delivery. Pharmaceutical Research. 26: 1847-55. PMID 19407933 DOI: 10.1007/S11095-009-9894-2  0.385
2009 Wang C, Muttil P, Lu D, Beltran-Torres AA, Garcia-Contreras L, Hickey AJ. Screening for potential adjuvants administered by the pulmonary route for tuberculosis vaccines. The Aaps Journal. 11: 139-47. PMID 19277872 DOI: 10.1208/S12248-009-9089-0  0.587
2009 Shi S, Ashley ES, Alexander BD, Hickey AJ. Initial characterization of micafungin pulmonary delivery via two different nebulizers and multivariate data analysis of aerosol mass distribution profiles. Aaps Pharmscitech. 10: 129-37. PMID 19189220 DOI: 10.1208/S12249-009-9185-6  0.579
2009 Sung JC, Garcia-Contreras L, Verberkmoes JL, Peloquin CA, Elbert KJ, Hickey AJ, Edwards DA. Dry powder nitroimidazopyran antibiotic PA-824 aerosol for inhalation. Antimicrobial Agents and Chemotherapy. 53: 1338-43. PMID 19139288 DOI: 10.1128/Aac.01389-08  0.439
2008 Cooney DJ, Hickey AJ. The generation of diesel exhaust particle aerosols from a bulk source in an aerodynamic size range similar to atmospheric particles. International Journal of Nanomedicine. 3: 435-49. PMID 19337412 DOI: 10.2147/Ijn.S1193  0.822
2008 Sivadas N, O'Rourke D, Tobin A, Buckley V, Ramtoola Z, Kelly JG, Hickey AJ, Cryan SA. A comparative study of a range of polymeric microspheres as potential carriers for the inhalation of proteins. International Journal of Pharmaceutics. 358: 159-67. PMID 18448288 DOI: 10.1016/J.Ijpharm.2008.03.024  0.385
2008 Garcia-Contreras L, Wong YL, Muttil P, Padilla D, Sadoff J, Derousse J, Germishuizen WA, Goonesekera S, Elbert K, Bloom BR, Miller R, Fourie PB, Hickey A, Edwards D. Immunization by a bacterial aerosol. Proceedings of the National Academy of Sciences of the United States of America. 105: 4656-60. PMID 18344320 DOI: 10.1073/Pnas.0800043105  0.486
2008 Garmise RJ, Hickey AJ. Calibration of the Andersen cascade impactor for the characterization of nasal products. Journal of Pharmaceutical Sciences. 97: 3462-6. PMID 18081008 DOI: 10.1002/Jps.21267  0.815
2008 Fiegel J, Garcia-Contreras L, Thomas M, VerBerkmoes J, Elbert K, Hickey A, Edwards D. Preparation and in vivo evaluation of a dry powder for inhalation of capreomycin. Pharmaceutical Research. 25: 805-11. PMID 17657592 DOI: 10.1007/S11095-007-9381-6  0.393
2007 Mansour HM, Hickey AJ. Raman characterization and chemical imaging of biocolloidal self-assemblies, drug delivery systems, and pulmonary inhalation aerosols: a review. Aaps Pharmscitech. 8: E99. PMID 18181559 DOI: 10.1208/Pt0804099  0.381
2007 Garmise RJ, Staats HF, Hickey AJ. Novel dry powder preparations of whole inactivated influenza virus for nasal vaccination. Aaps Pharmscitech. 8: E81. PMID 18181542 DOI: 10.1208/Pt0804081  0.801
2007 Lu D, Garcia-Contreras L, Xu D, Kurtz SL, Liu J, Braunstein M, McMurray DN, Hickey AJ. Poly (lactide-co-glycolide) microspheres in respirable sizes enhance an in vitro T cell response to recombinant Mycobacterium tuberculosis antigen 85B. Pharmaceutical Research. 24: 1834-43. PMID 17657598 DOI: 10.1007/S11095-007-9302-8  0.601
2007 Telko MJ, Hickey AJ. Critical assessment of inverse gas chromatography as means of assessing surface free energy and acid-base interaction of pharmaceutical powders. Journal of Pharmaceutical Sciences. 96: 2647-54. PMID 17518355 DOI: 10.1002/Jps.20897  0.762
2007 Garcia-Contreras L, Fiegel J, Telko MJ, Elbert K, Hawi A, Thomas M, VerBerkmoes J, Germishuizen WA, Fourie PB, Hickey AJ, Edwards D. Inhaled large porous particles of capreomycin for treatment of tuberculosis in a guinea pig model. Antimicrobial Agents and Chemotherapy. 51: 2830-6. PMID 17517845 DOI: 10.1128/Aac.01164-06  0.822
2007 Hickey AJ, Mansour HM, Telko MJ, Xu Z, Smyth HD, Mulder T, McLean R, Langridge J, Papadopoulos D. Physical characterization of component particles included in dry powder inhalers. II. Dynamic characteristics. Journal of Pharmaceutical Sciences. 96: 1302-19. PMID 17455364 DOI: 10.1002/Jps.20943  0.821
2007 Hickey AJ, Mansour HM, Telko MJ, Xu Z, Smyth HD, Mulder T, McLean R, Langridge J, Papadopoulos D. Physical characterization of component particles included in dry powder inhalers. I. Strategy review and static characteristics. Journal of Pharmaceutical Sciences. 96: 1282-301. PMID 17455324 DOI: 10.1002/Jps.20916  0.811
2007 Lu D, Hickey AJ. Pulmonary vaccine delivery. Expert Review of Vaccines. 6: 213-26. PMID 17408371 DOI: 10.1586/14760584.6.2.213  0.582
2007 Telko MJ, Kujanpää J, Hickey AJ. Investigation of triboelectric charging in dry powder inhalers using electrical low pressure impactor (ELPI). International Journal of Pharmaceutics. 336: 352-60. PMID 17218072 DOI: 10.1016/J.Ijpharm.2006.12.018  0.779
2006 Garmise RJ, Mar K, Crowder TM, Hwang CR, Ferriter M, Huang J, Mikszta JA, Sullivan VJ, Hickey AJ. Formulation of a dry powder influenza vaccine for nasal delivery. Aaps Pharmscitech. 7: E131-E137. PMID 28290034 DOI: 10.1208/Pt070119  0.814
2006 Smyth H, Hickey AJ, Brace G, Barbour T, Gallion J, Grove J. Spray pattern analysis for metered dose inhalers I: Orifice size, particle size, and droplet motion correlations. Drug Development and Industrial Pharmacy. 32: 1033-41. PMID 17012116 DOI: 10.1080/03639040600637598  0.412
2006 Garcia-Contreras L, Sethuraman V, Kazantseva M, Godfrey V, Hickey AJ. Evaluation of dosing regimen of respirable rifampicin biodegradable microspheres in the treatment of tuberculosis in the guinea pig Journal of Antimicrobial Chemotherapy. 58: 980-986. PMID 16971416 DOI: 10.1093/Jac/Dkl369  0.645
2006 Crowder T, Hickey A. Powder specific active dispersion for generation of pharmaceutical aerosols International Journal of Pharmaceutics. 327: 65-72. PMID 16930884 DOI: 10.1016/J.Ijpharm.2006.07.050  0.36
2006 Taylor MK, Hickey AJ, VanOort M. Manufacture, characterization, and pharmacodynamic evaluation of engineered ipratropium bromide particles. Pharmaceutical Development and Technology. 11: 321-36. PMID 16895843 DOI: 10.1080/10837450600769637  0.424
2006 Smyth H, Brace G, Barbour T, Gallion J, Grove J, Hickey AJ. Spray pattern analysis for metered dose inhalers: effect of actuator design. Pharmaceutical Research. 23: 1591-6. PMID 16783475 DOI: 10.1007/S11095-006-0280-Z  0.373
2006 Garmise RJ, Mar K, Crowder TM, Hwang CR, Ferriter M, Huang J, Mikszta JA, Sullivan VJ, Hickey AJ. Formulation of a dry powder influenza vaccine for nasal delivery. Aaps Pharmscitech. 7: E19. PMID 16584149 DOI: 10.1208/pt070119  0.816
2006 Hickey AJ, Lu D, Ashley ED, Stout J. Inhaled azithromycin therapy. Journal of Aerosol Medicine : the Official Journal of the International Society For Aerosols in Medicine. 19: 54-60. PMID 16551215 DOI: 10.1089/Jam.2006.19.54  0.642
2006 Louey MD, Van Oort M, Hickey AJ. Standardized entrainment tubes for the evaluation of pharmaceutical dry powder dispersion Journal of Aerosol Science. 37: 1520-1531. DOI: 10.1016/J.Jaerosci.2006.04.002  0.354
2005 Lu D, Hickey AJ. Liposomal dry powders as aerosols for pulmonary delivery of proteins. Aaps Pharmscitech. 6: E641-8. PMID 16408866 DOI: 10.1208/Pt060480  0.632
2005 Telko MJ, Hickey AJ. Dry powder inhaler formulation. Respiratory Care. 50: 1209-27. PMID 16122404  0.832
2005 Smyth HDC, Hickey AJ. Carriers in drug powder delivery: Implications for inhalation system design American Journal of Drug Delivery. 3: 117-132. DOI: 10.2165/00137696-200503020-00004  0.413
2004 Burgess DJ, Duffy E, Etzler F, Hickey AJ. Particle size analysis: AAPS workshop report, cosponsored by the Food and Drug Administration and the United States Pharmacopeia. The Aaps Journal. 6: e20. PMID 15760105 DOI: 10.1208/Aapsj060320  0.458
2004 Cooney D, Kazantseva M, Hickey AJ. Development of a size-dependent aerosol deposition model utilising human airway epithelial cells for evaluating aerosol drug delivery. Alternatives to Laboratory Animals : Atla. 32: 581-90. PMID 15757496 DOI: 10.1177/026119290403200609  0.8
2004 Huang J, Garmise RJ, Crowder TM, Mar K, Hwang CR, Hickey AJ, Mikszta JA, Sullivan VJ. A novel dry powder influenza vaccine and intranasal delivery technology: induction of systemic and mucosal immune responses in rats. Vaccine. 23: 794-801. PMID 15542204 DOI: 10.1016/J.Vaccine.2004.06.049  0.761
2004 Louey MD, Van Oort M, Hickey AJ. Aerosol dispersion of respirable particles in narrow size distributions using drug-alone and lactose-blend formulations. Pharmaceutical Research. 21: 1207-13. PMID 15290861 DOI: 10.1023/B:Pham.0000032991.74736.3E  0.465
2004 Louey MD, Van Oort M, Hickey AJ. Aerosol dispersion of respirable particles in narrow size distributions produced by jet-milling and spray-drying techniques. Pharmaceutical Research. 21: 1200-6. PMID 15290860 DOI: 10.1023/B:Pham.0000033007.27278.60  0.452
2004 Smyth HD, Beck VP, Williams D, Hickey AJ. The influence of formulation and spacer device on the in vitro performance of solution chlorofluorocarbon-free propellant-driven metered dose inhalers. Aaps Pharmscitech. 5: E7. PMID 15198528 DOI: 10.1208/Pt050107  0.435
2003 Sommerville ML, Hickey AJ. Aerosol generation by metered-dose inhalers containing dimethyl ether/propane inverse microemulsions. Aaps Pharmscitech. 4: E58. PMID 15198553 DOI: 10.1208/Pt040458  0.792
2003 Smyth HD, Hickey AJ. Multimodal particle size distributions emitted from HFA-134a solution pressurized metered-dose inhalers. Aaps Pharmscitech. 4: E38. PMID 14621970 DOI: 10.1208/pt040338  0.337
2003 Cooney DJ, Hickey AJ. Preparation of disodium fluorescein powders in association with lauric and capric acids. Journal of Pharmaceutical Sciences. 92: 2341-4. PMID 14603518 DOI: 10.1002/Jps.10488  0.755
2003 Garcia-Contreras L, Morçöl T, Bell SJ, Hickey AJ. Evaluation of novel particles as pulmonary delivery systems for insulin in rats. Aaps Pharmsci. 5: E9. PMID 12866936 DOI: 10.1208/Ps050209  0.339
2002 Sethuraman VV, Hickey AJ. Powder properties and their influence on dry powder inhaler delivery of an antitubercular drug. Aaps Pharmscitech. 3: E28. PMID 12916922 DOI: 10.1208/Pt030428  0.68
2002 Zhang Z, Kleinstreuer C, Kim CS, Hickey AJ. Aerosol transport and deposition in a triple bifurcation bronchial airway model with local tumors Inhalation Toxicology. 14: 1111-1133. PMID 12454794 DOI: 10.1080/08958370290084809  0.346
2002 Sommerville ML, Johnson CS, Cain JB, Rypacek F, Hickey AJ. Lecithin microemulsions in dimethyl ether and propane for the generation of pharmaceutical aerosols containing polar solutes. Pharmaceutical Development and Technology. 7: 273-88. PMID 12229259 DOI: 10.1081/Pdt-120005724  0.78
2002 Musante CJ, Schroeter JD, Rosati JA, Crowder TM, Hickey AJ, Martonen TB. Factors affecting the deposition of inhaled porous drug particles. Journal of Pharmaceutical Sciences. 91: 1590-600. PMID 12115821 DOI: 10.1002/Jps.10152  0.811
2002 Deaton AT, Jones LD, Dunbar CA, Hickey AJ, Williams DM. Generation of gelatin aerosol particles from nebulized solutions as model drug carrier systems. Pharmaceutical Development and Technology. 7: 147-53. PMID 12066570 DOI: 10.1081/Pdt-120003483  0.399
2002 Crowder TM, Rosati JA, Schroeter JD, Hickey AJ, Martonen TB. Fundamental effects of particle morphology on lung delivery: predictions of Stokes' law and the particular relevance to dry powder inhaler formulation and development. Pharmaceutical Research. 19: 239-45. PMID 11934228 DOI: 10.1023/A:1014426530935  0.806
2001 Sethuraman VV, Hickey AJ. Evaluation of preseparator performance for the 8-stage nonviable andersen impactor. Aaps Pharmscitech. 2: E4. PMID 14727889 DOI: 10.1208/Pt020104  0.694
2001 Suarez S, O'Hara P, Kazantseva M, Newcomer CE, Hopfer R, McMurray DN, Hickey AJ. Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis: Screening in an infectious disease model Pharmaceutical Research. 18: 1315-1319. PMID 11683246 DOI: 10.1023/A:1013094112861  0.348
2001 Hickey AJ, Garcia-Contreras L. Immunological and toxicological implications of short-term studies in animals of pharmaceutical aerosol delivery to the lungs: Relevance to humans Critical Reviews in Therapeutic Drug Carrier Systems. 18: 387-431. PMID 11605897 DOI: 10.1615/Critrevtherdrugcarriersyst.V18.I4.20  0.371
2001 Suarez S, O'Hara P, Kazantseva M, Newcomer CE, Hopfer R, McMurray DN, Hickey AJ. Airways delivery of rifampicin microparticles for the treatment of tuberculosis Journal of Antimicrobial Chemotherapy. 48: 431-434. PMID 11533012 DOI: 10.1093/Jac/48.3.431  0.317
2001 Suarez S, Kazantseva M, Bhat M, Costa D, Hickey AJ. The influence of suspension nebulization or instillation on particle uptake by guinea pig alveolar macrophages Inhalation Toxicology. 13: 773-788. PMID 11498805 DOI: 10.1080/089583701316941302  0.473
2001 Sethuraman VV, Hickey AJ. Evaluation preseparator performance for the 8-stage nonviable Andersen impactor Aaps Pharmscitech. 2.  0.665
2001 Crowder TM, Louey MD, Sethuraman VV, Smyth HDC, Hickey AJ. 2001: An odyssey in inhaler formulation and design Pharmaceutical Technology. 25: 99-113.  0.771
2000 Pettis RJ, Hall I, Costa D, Hickey AJ. Aerosol delivery of muramyl dipeptide to rodent lungs Aaps Pharmsci [Electronic Resource]. 2: E25. PMID 11741241 DOI: 10.1208/Ps020325  0.338
2000 O'Hara P, Hickey AJ. Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis: Manufacture and characterization Pharmaceutical Research. 17: 955-961. PMID 11028941 DOI: 10.1023/A:1007527204887  0.484
2000 Suarez S, Hickey AJ. Drug properties affecting aerosol behavior Respiratory Care. 45: 652-666. PMID 10894458  0.301
2000 Sommerville ML, Cain JB, Johnson CS, Hickey AJ. Lecithin inverse microemulsions for the pulmonary delivery of polar compounds utilizing dimethylether and propane as propellants. Pharmaceutical Development and Technology. 5: 219-30. PMID 10810752 DOI: 10.1081/Pdt-100100537  0.784
2000 Dunbar CA, Hickey AJ. Evaluation of probability density functions to approximate particle size distributions of representative pharmaceutical aerosols Journal of Aerosol Science. 31: 813-831. DOI: 10.1016/S0021-8502(99)00557-1  0.338
1999 Dunbar CA, Hickey AJ. Selected parameters affecting characterization of nebulized aqueous solutions by inertial impaction and comparison with phase-Doppler analysis. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 48: 171-7. PMID 10469935 DOI: 10.1016/S0939-6411(99)00031-4  0.342
1999 Concessio NM, VanOort MM, Knowles MR, Hickey AJ. Pharmaceutical dry powder aerosols: correlation of powder properties with dose delivery and implications for pharmacodynamic effect. Pharmaceutical Research. 16: 828-34. PMID 10397601 DOI: 10.1023/A:1018865717374  0.391
1999 Dunbar CA, Concessio NM, Hickey AJ. Evaluation of atomizer performance in production of respirable spray-dried particles. Pharmaceutical Development and Technology. 3: 433-41. PMID 9834945 DOI: 10.3109/10837459809028624  0.401
1999 Crowder TM, Sethuraman V, Fields TB, Hickey AJ. Signal processing and analysis applied to powder behavior in a rotating drum Particle and Particle Systems Characterization. 16: 191-196. DOI: 10.1002/(Sici)1521-4117(199908)16:4<191::Aid-Ppsc191>3.0.Co;2-0  0.767
1999 Crowder TM, Hickey AJ. An Instrument for Rapid Powder Flow Measurement and Temporal Fractal Analysis Particle & Particle Systems Characterization. 16: 32-34. DOI: 10.1002/(Sici)1521-4117(199905)16:1<32::Aid-Ppsc32>3.0.Co;2-8  0.739
1998 Dunber CA, Hickey AJ, Holzner P. Dispersion and Characterization of Pharmaceutical Dry Powder Aerosols Kona Powder and Particle Journal. 16: 7-45. DOI: 10.14356/Kona.1998007  0.403
1997 Concessio N, Hickey A. Descriptors of irregular particle morphology and powder properties Advanced Drug Delivery Reviews. 26: 29-40. PMID 10837530 DOI: 10.1016/S0169-409X(97)00508-5  0.465
1997 Fults KA, Miller IF, Hickey AJ. Effect of particle morphology on emitted dose of fatty acid-treated disodium cromoglycate powder aerosols. Pharmaceutical Development and Technology. 2: 67-79. PMID 9552432 DOI: 10.3109/10837459709022610  0.362
1997 Hickey AJ, Martonen TB, Yang Y. Theoretical relationship of lung deposition to the fine particle fraction of inhalation aerosols. Pharmaceutica Acta Helvetiae. 71: 185-90. PMID 8818308 DOI: 10.1016/0031-6865(96)00014-3  0.458
1997 Hickey AJ, Lalor CB, Fu D, Zopf D. Nebulizer Delivery Of Oligosaccharide Solution Aerosols Particulate Science and Technology. 15: 203-216. DOI: 10.1080/02726359708906768  0.401
1997 CONCESSIO NM, JÄGER-WALDAU R, HICKEY AJ. AEROSOL DELIVERY FROM AN ACTIVE EMISSION MULTI-SINGLE DOSE DRY POWDER INHALER Particulate Science and Technology. 15: 51-63. DOI: 10.1080/02726359708906709  0.372
1994 Pillai RS, Yeates DB, Eljamal M, Miller IF, Hickey AJ. Generation of concentrated aerosols for inhalation studies Journal of Aerosol Science. 25: 187-197. DOI: 10.1016/0021-8502(94)90190-2  0.31
1994 Hickey AJ, Concessio NM. Flow Properties of Selected Pharmaceutical Powders from a Vibrating Spatula Particle & Particle Systems Characterization. 11: 457-462. DOI: 10.1002/Ppsc.19940110609  0.324
1993 Hickey AJ, Martonen TB. Behavior of hygroscopic pharmaceutical aerosols and the influence of hydrophobic additives. Pharmaceutical Research. 10: 1-7. PMID 8430044 DOI: 10.1023/A:1018952425107  0.332
1993 Martonen TB, Katz I, Fults K, Hickey AJ. Use of analytically defined estimates of aerosol respirable fraction to predict lung deposition patterns. Pharmaceutical Research. 9: 1634-9. PMID 1488409 DOI: 10.1023/A:1015880828704  0.348
1988 Hickey AJ, Dalby RN, Byron PR. Effects of surfactants on aerosol powders in suspension. Implications for airborne particle size International Journal of Pharmaceutics. 42: 267-270. DOI: 10.1016/0378-5173(88)90186-X  0.364
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