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David A. Brafman, Ph.D. - Publications

Affiliations: 
2009 Bioengineering University of California, San Diego, La Jolla, CA 
Area:
Biomedical
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45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Frisch C, Kostes WW, Galyon B, Whitman B, Tekel SJ, Standage-Beier K, Srinivasan G, Wang X, Brafman DA. PINE-TREE enables highly efficient genetic modification of human cell lines. Molecular Therapy. Nucleic Acids. 33: 483-492. PMID 37588683 DOI: 10.1016/j.omtn.2023.07.007  0.353
2022 Knittel J, Srinivasan G, Frisch C, Brookhouser N, Raman S, Essuman A, Brafman DA. A microcarrier-based protocol for scalable generation and purification of human induced pluripotent stem cell-derived neurons and astrocytes. Star Protocols. 3: 101632. PMID 36035791 DOI: 10.1016/j.xpro.2022.101632  0.42
2021 Cook M, Richey A, Brafman DA, Frow EK. Weighing up the evidence used by direct-to-consumer stem cell businesses. Stem Cell Reports. PMID 34767748 DOI: 10.1016/j.stemcr.2021.10.007  0.429
2021 Cutts J, Kostes W, Brafman DA. Generation of 3X FLAG-tagged human embryonic stem cell (hESC) line to study WNT-induced β-catenin DNA interactions (HVRDe009-A-2). Stem Cell Research. 57: 102586. PMID 34736039 DOI: 10.1016/j.scr.2021.102586  0.455
2021 Tekel SJ, Brookhouser N, Standage-Beier K, Wang X, Brafman DA. Cytosine and adenosine base editing in human pluripotent stem cells using transient reporters for editing enrichment. Nature Protocols. PMID 34172975 DOI: 10.1038/s41596-021-00552-y  0.371
2020 Veldhuizen J, Cutts J, Brafman DA, Migrino RQ, Nikkhah M. Engineering anisotropic human stem cell-derived three-dimensional cardiac tissue on-a-chip. Biomaterials. 256: 120195. PMID 32623207 DOI: 10.1016/J.Biomaterials.2020.120195  0.421
2020 Raman S, Srinivasan G, Brookhouser N, Nguyen T, Henson T, Morgan D, Cutts J, Brafman DA. A Defined and Scalable Peptide-Based Platform for the Generation of Human Pluripotent Stem Cell-Derived Astrocytes. Acs Biomaterials Science & Engineering. 6: 3477-3490. PMID 32550261 DOI: 10.1021/Acsbiomaterials.0C00067  0.49
2020 Raman S, Brookhouser N, Brafman DA. Using human induced pluripotent stem cells (hiPSCs) to investigate the mechanisms by which Apolipoprotein E (APOE) contributes to Alzheimer's disease (AD) risk. Neurobiology of Disease. 104788. PMID 32032733 DOI: 10.1016/J.Nbd.2020.104788  0.328
2020 Brookhouser N, Tekel SJ, Standage-Beier K, Nguyen T, Schwarz G, Wang X, Brafman DA. BIG-TREE: Base-Edited Isogenic hPSC Line Generation Using a Transient Reporter for Editing Enrichment. Stem Cell Reports. PMID 32004495 DOI: 10.1016/J.Stemcr.2019.12.013  0.412
2020 Standage-Beier K, Tekel SJ, Brookhouser N, Schwarz G, Nguyen T, Wang X, Brafman DA. A transient reporter for editing enrichment (TREE) in human cells. Nucleic Acids Research. PMID 31943066 DOI: 10.1093/nar/gkaa027  0.323
2019 Standage-Beier K, Tekel SJ, Brookhouser N, Schwarz G, Nguyen T, Wang X, Brafman DA. A transient reporter for editing enrichment (TREE) in human cells. Nucleic Acids Research. PMID 31428784 DOI: 10.1093/Nar/Gkz713  0.449
2019 Frow EK, Brafman DA, Muldoon A, Krum L, Williams P, Becker B, Nelson JP, Pritchett A. Characterizing Direct-to-Consumer Stem Cell Businesses in the Southwest United States. Stem Cell Reports. PMID 31378670 DOI: 10.1016/J.Stemcr.2019.07.001  0.491
2018 Brookhouser N, Zhang P, Caselli R, Kim JJ, Brafman DA. Generation and characterization of two human induced pluripotent stem cell (hiPSC) lines homozygous for the Apolipoprotein e4 (APOE4) risk variant-Alzheimer's disease (ASUi005-A) and healthy non-demented control (ASUi006-A). Stem Cell Research. 32: 145-149. PMID 30296667 DOI: 10.1016/J.Scr.2018.09.007  0.445
2018 Srinivasan G, Morgan D, Varun D, Brookhouser N, Brafman DA. An integrated biomanufacturing platform for the large-scale expansion and neuronal differentiation of human pluripotent stem cell-derived neural progenitor cells. Acta Biomaterialia. PMID 29775730 DOI: 10.1016/J.Actbio.2018.05.008  0.506
2017 Brookhouser N, Zhang P, Caselli R, Kim JJ, Brafman DA. Generation and characterization of human induced pluripotent stem cell (hiPSC) lines from an Alzheimer's disease (ASUi003-A) and non-demented control (ASUi004-A) patient homozygous for the Apolipoprotein e4 (APOE4) risk variant. Stem Cell Research. 25: 266-269. PMID 29246571 DOI: 10.1016/J.Scr.2017.07.003  0.441
2017 Huggins IJ, Bos T, Gaylord O, Jessen C, Lonquich B, Puranen A, Richter J, Rossdam C, Brafman D, Gaasterland T, Willert K. The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells. Nature Communications. 8: 1034. PMID 29044119 DOI: 10.1038/S41467-017-01203-1  0.714
2017 Brookhouser N, Zhang P, Caselli R, Kim JJ, Brafman DA. Generation and characterization of human induced pluripotent stem cell (hiPSC) lines from an Alzheimer's disease (ASUi001-A) and non-demented control (ASUi002-A) patient homozygous for the Apolipoprotein e4 (APOE4) risk variant. Stem Cell Research. 24: 160-163. PMID 29034886 DOI: 10.1016/J.Scr.2017.06.003  0.441
2017 Brafman D, Willert K. Wnt/β-catenin signaling during early vertebrate neural development. Developmental Neurobiology. PMID 28799266 DOI: 10.1002/Dneu.22517  0.712
2017 Brookhouser N, Raman S, Potts C, Brafman DA. May I Cut in? Gene Editing Approaches in Human Induced Pluripotent Stem Cells. Cells. 6. PMID 28178187 DOI: 10.3390/Cells6010005  0.454
2016 Varun D, Rajaram Srinivasan G, Tsai YH, Kim HJ, Cutts J, Petty F, Merkley R, Stephanopoulos N, Dolezalova D, Marsala M, Brafman DA. A robust vitronectin-derived peptide for the scalable long-term expansion and neuronal differentiation of human pluripotent stem cell (hPSC)-derived neural progenitor cells (hNPCs). Acta Biomaterialia. PMID 27989923 DOI: 10.1016/J.Actbio.2016.10.037  0.524
2016 Daer R, Cutts JP, Brafman DA, Haynes KA. The impact of chromatin dynamics on Cas9-mediated genome editing in human cells. Acs Synthetic Biology. PMID 27783893 DOI: 10.1021/Acssynbio.5B00299  0.316
2016 Huggins IJ, Brafman D, Willert K. Methods to Manipulate and Monitor Wnt Signaling in Human Pluripotent Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 1481: 161-81. PMID 27590161 DOI: 10.1007/978-1-4939-6393-5_16  0.76
2016 Kharaziha M, Memic A, Akbari M, Brafman DA, Nikkhah M. Tissue Engineering: Nano-Enabled Approaches for Stem Cell-Based Cardiac Tissue Engineering(Adv. Healthcare Mater. 13/2016). Advanced Healthcare Materials. 5: 1532. PMID 27384932 DOI: 10.1002/Adhm.201670066  0.379
2016 Lou CH, Dumdie J, Goetz A, Shum EY, Brafman D, Liao X, Mora-Castilla S, Ramaiah M, Cook-Andersen H, Laurent L, Wilkinson MF. Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate. Stem Cell Reports. 6: 844-857. PMID 27304915 DOI: 10.1016/J.Stemcr.2016.05.008  0.529
2016 Kharaziha M, Memic A, Akbari M, Brafman DA, Nikkhah M. Nano-Enabled Approaches for Stem Cell-Based Cardiac Tissue Engineering. Advanced Healthcare Materials. PMID 27199266 DOI: 10.1002/Adhm.201600088  0.473
2016 Cutts J, Brookhouser N, Brafman DA. Generation of Regionally Specific Neural Progenitor Cells (NPCs) and Neurons from Human Pluripotent Stem Cells (hPSCs). Methods in Molecular Biology (Clifton, N.J.). PMID 27106497 DOI: 10.1007/7651_2016_357  0.552
2015 Navaei A, Truong D, Heffernan J, Cutts J, Brafman D, Sirianni RW, Vernon B, Nikkhah M. PNIPAAm-based biohybrid injectable hydrogel for cardiac tissue engineering. Acta Biomaterialia. PMID 26689467 DOI: 10.1016/J.Actbio.2015.12.019  0.401
2015 Kumar N, Richter J, Cutts J, Bush KT, Trujillo C, Nigam SK, Gaasterland T, Brafman D, Willert K. Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells. Elife. 4. PMID 26554899 DOI: 10.7554/Elife.08413  0.746
2015 Brafman D, Campbell S, Lam AQ, Kim JJ, Nikkhah M, Stabenfeldt S. Stem Cell Biology. Biomarker Insights. 10: 133-7. PMID 26339185 DOI: 10.4137/Bmi.S31471  0.567
2015 Cutts J, Nikkhah M, Brafman DA. Biomaterial Approaches for Stem Cell-Based Myocardial Tissue Engineering. Biomarker Insights. 10: 77-90. PMID 26052226 DOI: 10.4137/Bmi.S20313  0.545
2015 Tsai Y, Cutts J, Kimura A, Varun D, Brafman DA. A chemically defined substrate for the expansion and neuronal differentiation of human pluripotent stem cell-derived neural progenitor cells. Stem Cell Research. 15: 75-87. PMID 26002631 DOI: 10.1016/J.Scr.2015.05.002  0.595
2015 Brafman DA. Generation, Expansion, and Differentiation of Human Pluripotent Stem Cell (hPSC) Derived Neural Progenitor Cells (NPCs). Methods in Molecular Biology (Clifton, N.J.). 1212: 87-102. PMID 25063499 DOI: 10.1007/7651_2014_90  0.596
2015 Kumar N, Richter J, Cutts J, Bush KT, Trujillo C, Nigam SK, Gaasterland T, Brafman D, Willert K. Author response: Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells Elife. DOI: 10.7554/Elife.08413.029  0.736
2015 Tsai Y, Cutts J, Kimura A, Varun D, Brafman DA. A chemically defined substrate for the expansion and neuronal differentiation of human pluripotent stem cell-derived neural progenitor cells Stem Cell Research. 15: 75-87. DOI: 10.1016/j.scr.2015.05.002  0.489
2014 Ross J, Busch J, Mintz E, Ng D, Stanley A, Brafman D, Sutton VR, Van den Veyver I, Willert K. A rare human syndrome provides genetic evidence that WNT signaling is required for reprogramming of fibroblasts to induced pluripotent stem cells. Cell Reports. 9: 1770-80. PMID 25464842 DOI: 10.1016/J.Celrep.2014.10.049  0.698
2014 Moya N, Cutts J, Gaasterland T, Willert K, Brafman DA. Endogenous WNT signaling regulates hPSC-derived neural progenitor cell heterogeneity and specifies their regional identity. Stem Cell Reports. 3: 1015-28. PMID 25458891 DOI: 10.1016/J.Stemcr.2014.10.004  0.698
2014 Fernandez A, Huggins IJ, Perna L, Brafman D, Lu D, Yao S, Gaasterland T, Carson DA, Willert K. The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 1409-14. PMID 24474766 DOI: 10.1073/Pnas.1323697111  0.744
2013 Brafman DA, Moya N, Allen-Soltero S, Fellner T, Robinson M, McMillen ZL, Gaasterland T, Willert K. Analysis of SOX2-expressing cell populations derived from human pluripotent stem cells. Stem Cell Reports. 1: 464-78. PMID 24286033 DOI: 10.1016/J.Stemcr.2013.09.005  0.745
2013 Brafman DA. Constructing stem cell microenvironments using bioengineering approaches. Physiological Genomics. 45: 1123-35. PMID 24064536 DOI: 10.1152/Physiolgenomics.00099.2013  0.587
2013 Brafman DA, Phung C, Kumar N, Willert K. Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions. Cell Death and Differentiation. 20: 369-81. PMID 23154389 DOI: 10.1038/Cdd.2012.138  0.764
2012 Brafman DA, Chien S, Willert K. Arrayed cellular microenvironments for identifying culture and differentiation conditions for stem, primary and rare cell populations. Nature Protocols. 7: 703-17. PMID 22422316 DOI: 10.1038/Nprot.2012.017  0.747
2010 Brafman DA, Chang CW, Fernandez A, Willert K, Varghese S, Chien S. Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces. Biomaterials. 31: 9135-44. PMID 20817292 DOI: 10.1016/J.Biomaterials.2010.08.007  0.699
2009 Brafman DA, de Minicis S, Seki E, Shah KD, Teng D, Brenner D, Willert K, Chien S. Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 513-24. PMID 20023766 DOI: 10.1039/B912926J  0.68
2009 Brafman DA, Shah KD, Fellner T, Chien S, Willert K. Defining long-term maintenance conditions of human embryonic stem cells with arrayed cellular microenvironment technology. Stem Cells and Development. 18: 1141-54. PMID 19327010 DOI: 10.1089/Scd.2008.0410  0.735
2008 De Minicis S, Brafman D, Marzioni M, Seki E, Willert K, Chien S, Benedetti A, Brenner DA. Extracellular matrix combinations differentially modulate hepatic stellate cell biology Digestive and Liver Disease. 40: A132-A133. DOI: 10.1016/J.Dld.2008.07.164  0.666
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