Shannon M. Conley, Ph.D. - Publications

Affiliations: 
2006 University of Arizona, Tucson, AZ 
Area:
Biomedical, Physiology, Ophthalmology

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kakakhel M, Tebbe L, Makia MS, Conley SM, Sherry DM, Al-Ubaidi MR, Naash MI. Syntaxin 3 is essential for photoreceptor outer segment protein trafficking and survival. Proceedings of the National Academy of Sciences of the United States of America. PMID 32778589 DOI: 10.1073/pnas.2010751117  1
2020 Strayve D, Makia MM, Kakakhel M, Sakthivel H, Conley SM, Al-Ubaidi MR, Naash MI. ROM1 contributes to phenotypic heterogeneity in PRPH2-associated retinal disease. Human Molecular Genetics. PMID 32716032 DOI: 10.1093/hmg/ddaa160  1
2020 Genc AM, Makia MS, Sinha T, Conley SM, Al-Ubaidi MR, Naash MI. Elimination of a Retinal Riboflavin Binding Protein Exacerbates Degeneration in a Model of Cone-Rod Dystrophy. Investigative Ophthalmology & Visual Science. 61: 17. PMID 32516403 DOI: 10.1167/iovs.61.6.17  1
2020 Chakraborty D, Strayve DG, Makia MS, Conley SM, Kakahel M, Al-Ubaidi MR, Naash MI. Novel molecular mechanisms for Prph2-associated pattern dystrophy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 1211-1230. PMID 31914632 DOI: 10.1096/fj.201901888R  1
2019 Conley SM, Al-Ubaidi MR, Naash MI. The Role of the Prph2 C-Terminus in Outer Segment Morphogenesis. Advances in Experimental Medicine and Biology. 1185: 495-499. PMID 31884660 DOI: 10.1007/978-3-030-27378-1_81  1
2018 Conley SM, Stuck MW, Watson JN, Zulliger R, Burnett JL, Naash MI. Prph2 initiates outer segment morphogenesis but maturation requires Prph2/Rom1 oligomerization. Human Molecular Genetics. PMID 30307502 DOI: 10.1093/hmg/ddy359  1
2018 Agbaga MG, Merriman DK, Brush RS, Lydic TA, Conley SM, Naash MI, Jackson S, Woods AS, Reid GE, Busik JV, Anderson RE. Differential Composition of DHA and Very Long Chain PUFAs in Rod and Cone Photoreceptors. Journal of Lipid Research. PMID 29986998 DOI: 10.1194/jlr.M082495  1
2018 Zulliger R, Conley SM, Mwoyosvi ML, Al-Ubaidi MR, Naash MI. Oligomerization of Prph2 and Rom1 is essential for photoreceptor outer segment formation. Human Molecular Genetics. PMID 29961824 DOI: 10.1093/hmg/ddy240  1
2018 Kelley RA, Conley SM, Makkia R, Watson JN, Han Z, Cooper MJ, Naash MI. DNA nanoparticles are safe and nontoxic in non-human primate eyes. International Journal of Nanomedicine. 13: 1361-1379. PMID 29563793 DOI: 10.2147/IJN.S157000  1
2017 Conley SM, Stuck MW, Watson JN, Naash MI. Rom1 converts Y141C-Prph2-associated pattern dystrophy to retinitis pigmentosa. Human Molecular Genetics. PMID 28053051 DOI: 10.1093/hmg/ddw408  1
2016 Chakraborty D, Conley SM, Zulliger R, Naash MI. The K153Del PRPH2 mutation differentially impacts photoreceptor structure and function. Human Molecular Genetics. PMID 27365499 DOI: 10.1093/hmg/ddw193  1
2016 Chakraborty D, Conley SM, Pittler SJ, Naash MI. Role of RDS and Rhodopsin in Cngb1-Related Retinal Degeneration. Investigative Ophthalmology & Visual Science. 57: 787-97. PMID 26934134 DOI: 10.1167/iovs.15-18516  1
2016 Stuck MW, Conley SM, Naash MI. PRPH2/RDS and ROM-1: Historical context, current views and future considerations. Progress in Retinal and Eye Research. PMID 26773759 DOI: 10.1016/j.preteyeres.2015.12.002  1
2016 Conley SM, Whalen P, Lewin AS, Naash MI. Characterization of Ribozymes Targeting a Congenital Night Blindness Mutation in Rhodopsin Mutation. Advances in Experimental Medicine and Biology. 854: 509-15. PMID 26427453 DOI: 10.1007/978-3-319-17121-0_68  1
2016 Mitra RN, Conley SM, Naash MI. Therapeutic Approach of Nanotechnology for Oxidative Stress Induced Ocular Neurodegenerative Diseases. Advances in Experimental Medicine and Biology. 854: 463-9. PMID 26427447 DOI: 10.1007/978-3-319-17121-0_62  1
2016 Stuck MW, Conley SM, Naash MI. RDS Functional Domains and Dysfunction in Disease. Advances in Experimental Medicine and Biology. 854: 217-22. PMID 26427414 DOI: 10.1007/978-3-319-17121-0_29  1
2015 Chakraborty D, Conley SM, DeRamus ML, Pittler SJ, Naash MI. Varying the GARP2-to-RDS Ratio Leads to Defects in Rim Formation and Rod and Cone Function. Investigative Ophthalmology & Visual Science. 56: 8187-98. PMID 26720471 DOI: 10.1167/iovs.15-17785  1
2015 Zulliger R, Conley SM, Naash MI. Non-viral therapeutic approaches to ocular diseases: An overview and future directions. Journal of Controlled Release : Official Journal of the Controlled Release Society. 219: 471-87. PMID 26439665 DOI: 10.1016/j.jconrel.2015.10.007  1
2015 Stuck MW, Conley SM, Naash MI. Retinal Degeneration Slow (RDS) Glycosylation Plays a Role in Cone Function and in the Regulation of RDS·ROM-1 Protein Complex Formation. The Journal of Biological Chemistry. 290: 27901-13. PMID 26420485 DOI: 10.1074/jbc.M115.683698  1
2015 Zulliger R, Conley SM, Mwoyosvi ML, Stuck MW, Azadi S, Naash MI. SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting. Plos One. 10: e0138508. PMID 26406599 DOI: 10.1371/journal.pone.0138508  1
2015 Han Z, Banworth MJ, Makkia R, Conley SM, Al-Ubaidi MR, Cooper MJ, Naash MI. Genomic DNA nanoparticles rescue rhodopsin-associated retinitis pigmentosa phenotype. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2535-44. PMID 25713057 DOI: 10.1096/fj.15-270363  1
2014 Conley SM, Naash MI. Gene therapy for PRPH2-associated ocular disease: challenges and prospects. Cold Spring Harbor Perspectives in Medicine. 4: a017376. PMID 25167981 DOI: 10.1101/cshperspect.a017376  1
2014 Mitra RN, Merwin MJ, Han Z, Conley SM, Al-Ubaidi MR, Naash MI. Yttrium oxide nanoparticles prevent photoreceptor death in a light-damage model of retinal degeneration. Free Radical Biology & Medicine. 75: 140-8. PMID 25066531 DOI: 10.1016/j.freeradbiomed.2014.07.013  1
2014 Stuck MW, Conley SM, Naash MI. The Y141C knockin mutation in RDS leads to complex phenotypes in the mouse. Human Molecular Genetics. 23: 6260-74. PMID 25001182 DOI: 10.1093/hmg/ddu345  1
2014 Chakraborty D, Conley SM, Al-Ubaidi MR, Naash MI. Initiation of rod outer segment disc formation requires RDS. Plos One. 9: e98939. PMID 24897172 DOI: 10.1371/journal.pone.0098939  1
2014 Conley SM, Al-Ubaidi MR, Han Z, Naash MI. Rim formation is not a prerequisite for distribution of cone photoreceptor outer segment proteins. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 3468-79. PMID 24736412 DOI: 10.1096/fj.14-251397  1
2014 Han Z, Conley SM, Naash MI. Gene therapy for Stargardt disease associated with ABCA4 gene. Advances in Experimental Medicine and Biology. 801: 719-24. PMID 24664763 DOI: 10.1007/978-1-4614-3209-8_90  1
2014 Koirala A, Conley SM, Naash MI. Episomal maintenance of S/MAR-containing non-viral vectors for RPE-based diseases. Advances in Experimental Medicine and Biology. 801: 703-9. PMID 24664761 DOI: 10.1007/978-1-4614-3209-8_88  1
2014 Stuck MW, Conley SM, Shaw RA, Wolf R, Naash MI. Electrophysiological characterization of rod and cone responses in the baboon nonhuman primate model. Advances in Experimental Medicine and Biology. 801: 67-73. PMID 24664682 DOI: 10.1007/978-1-4614-3209-8_9  1
2014 Conley SM, Stuck MW, Burnett JL, Chakraborty D, Azadi S, Fliesler SJ, Naash MI. Insights into the mechanisms of macular degeneration associated with the R172W mutation in RDS. Human Molecular Genetics. 23: 3102-14. PMID 24463884 DOI: 10.1093/hmg/ddu014  1
2014 Mitra RN, Han Z, Merwin M, Al Taai M, Conley SM, Naash MI. Synthesis and characterization of glycol chitosan DNA nanoparticles for retinal gene delivery. Chemmedchem. 9: 189-96. PMID 24203490 DOI: 10.1002/cmdc.201300371  1
2013 Al-Ubaidi MR, Naash MI, Conley SM. A perspective on the role of the extracellular matrix in progressive retinal degenerative disorders. Investigative Ophthalmology & Visual Science. 54: 8119-24. PMID 24346621 DOI: 10.1167/iovs.13-13536  1
2013 Koirala A, Conley SM, Makkia R, Liu Z, Cooper MJ, Sparrow JR, Naash MI. Persistence of non-viral vector mediated RPE65 expression: case for viability as a gene transfer therapy for RPE-based diseases. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 745-52. PMID 24035979 DOI: 10.1016/j.jconrel.2013.08.299  1
2013 Koirala A, Conley SM, Naash MI. A review of therapeutic prospects of non-viral gene therapy in the retinal pigment epithelium. Biomaterials. 34: 7158-67. PMID 23796578 DOI: 10.1016/j.biomaterials.2013.06.002  1
2013 Chakraborty D, Conley SM, Naash MI. Overexpression of retinal degeneration slow (RDS) protein adversely affects rods in the rd7 model of enhanced S-cone syndrome. Plos One. 8: e63321. PMID 23650562 DOI: 10.1371/journal.pone.0063321  1
2013 Koirala A, Makkia RS, Conley SM, Cooper MJ, Naash MI. S/MAR-containing DNA nanoparticles promote persistent RPE gene expression and improvement in RPE65-associated LCA. Human Molecular Genetics. 22: 1632-42. PMID 23335596 DOI: 10.1093/hmg/ddt013  1
2013 Han Z, Guo J, Conley SM, Naash MI. Retinal angiogenesis in the Ins2(Akita) mouse model of diabetic retinopathy. Investigative Ophthalmology & Visual Science. 54: 574-84. PMID 23221078 DOI: 10.1167/iovs.12-10959  1
2013 Chakraborty D, Rodgers KK, Conley SM, Naash MI. Structural characterization of the second intra-discal loop of the photoreceptor tetraspanin RDS. The Febs Journal. 280: 127-38. PMID 23121719 DOI: 10.1111/febs.12055  1
2012 Han Z, Conley SM, Makkia R, Guo J, Cooper MJ, Naash MI. Comparative analysis of DNA nanoparticles and AAVs for ocular gene delivery. Plos One. 7: e52189. PMID 23272225 DOI: 10.1371/journal.pone.0052189  1
2012 Han Z, Conley SM, Makkia RS, Cooper MJ, Naash MI. DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice. The Journal of Clinical Investigation. 122: 3221-6. PMID 22886305 DOI: 10.1172/JCI64833  1
2012 Stuck MW, Conley SM, Naash MI. Defects in the outer limiting membrane are associated with rosette development in the Nrl-/- retina. Plos One. 7: e32484. PMID 22427845 DOI: 10.1371/journal.pone.0032484  1
2012 Vuong L, Conley SM, Al-Ubaidi MR. Expression and role of p53 in the retina. Investigative Ophthalmology & Visual Science. 53: 1362-71. PMID 22427613 DOI: 10.1167/iovs.11-8909  1
2012 Conley SM, Chakraborty D, Naash MI. Mislocalization of oligomerization-incompetent RDS is associated with mislocalization of cone opsins and cone transducin. Advances in Experimental Medicine and Biology. 723: 657-62. PMID 22183390 DOI: 10.1007/978-1-4614-0631-0_83  1
2012 Chakraborty D, Conley SM, Nash Z, Ding XQ, Naash MI. Overexpression of ROM-1 in the cone-dominant retina. Advances in Experimental Medicine and Biology. 723: 633-9. PMID 22183387 DOI: 10.1007/978-1-4614-0631-0_80  1
2012 Conley SM, Cai X, Makkia R, Wu Y, Sparrow JR, Naash MI. Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy. Biochimica Et Biophysica Acta. 1822: 1169-79. PMID 22033104 DOI: 10.1016/j.bbadis.2011.10.007  1
2012 Conley SM, Stuck MW, Naash MI. Structural and functional relationships between photoreceptor tetraspanins and other superfamily members. Cellular and Molecular Life Sciences : Cmls. 69: 1035-47. PMID 21655915 DOI: 10.1007/s00018-011-0736-0  1
2011 Han Z, Conley SM, Naash MI. AAV and compacted DNA nanoparticles for the treatment of retinal disorders: challenges and future prospects. Investigative Ophthalmology & Visual Science. 52: 3051-9. PMID 21558483 DOI: 10.1167/iovs.10-6916  1
2010 Chakraborty D, Conley SM, Stuck MW, Naash MI. Differences in RDS trafficking, assembly and function in cones versus rods: insights from studies of C150S-RDS. Human Molecular Genetics. 19: 4799-812. PMID 20858597 DOI: 10.1093/hmg/ddq410  1
2010 Conley SM, Naash MI. Nanoparticles for retinal gene therapy. Progress in Retinal and Eye Research. 29: 376-97. PMID 20452457 DOI: 10.1016/j.preteyeres.2010.04.004  1
2010 Cai X, Conley SM, Cheng T, Al-Ubaidi MR, Naash MI. A 350 bp region of the proximal promoter of Rds drives cell-type specific gene expression. Experimental Eye Research. 91: 186-94. PMID 20447394 DOI: 10.1016/j.exer.2010.04.017  1
2010 Cai X, Conley SM, Naash MI. Gene therapy in the Retinal Degeneration Slow model of retinitis pigmentosa. Advances in Experimental Medicine and Biology. 664: 611-9. PMID 20238065 DOI: 10.1007/978-1-4419-1399-9_70  1
2010 Conley SM, Ding XQ, Naash MI. RDS in cones does not interact with the beta subunit of the cyclic nucleotide gated channel. Advances in Experimental Medicine and Biology. 664: 63-70. PMID 20238003 DOI: 10.1007/978-1-4419-1399-9_8  1
2010 Chakraborty D, Conley SM, Fliesler SJ, Naash MI. The function of oligomerization-incompetent RDS in rods. Advances in Experimental Medicine and Biology. 664: 39-46. PMID 20238000 DOI: 10.1007/978-1-4419-1399-9_5  1
2010 Conley SM, Stricker HM, Naash MI. Biochemical analysis of phenotypic diversity associated with mutations in codon 244 of the retinal degeneration slow gene. Biochemistry. 49: 905-11. PMID 20055437 DOI: 10.1021/bi901622w  1
2010 Cai X, Conley SM, Nash Z, Fliesler SJ, Cooper MJ, Naash MI. Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1178-91. PMID 19952284 DOI: 10.1096/fj.09-139147  1
2009 Ding XQ, Quiambao AB, Fitzgerald JB, Cooper MJ, Conley SM, Naash MI. Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina. Plos One. 4: e7410. PMID 19823583 DOI: 10.1371/journal.pone.0007410  1
2009 Cai X, Nash Z, Conley SM, Fliesler SJ, Cooper MJ, Naash MI. A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles. Plos One. 4: e5290. PMID 19390689 DOI: 10.1371/journal.pone.0005290  1
2009 Cai X, Conley SM, Naash MI. RPE65: role in the visual cycle, human retinal disease, and gene therapy. Ophthalmic Genetics. 30: 57-62. PMID 19373675 DOI: 10.1080/13816810802626399  1
2009 Conley SM, Naash MI. Focus on molecules: RDS. Experimental Eye Research. 89: 278-9. PMID 19366620 DOI: 10.1016/j.exer.2009.03.023  1
2009 Chakraborty D, Ding XQ, Conley SM, Fliesler SJ, Naash MI. Differential requirements for retinal degeneration slow intermolecular disulfide-linked oligomerization in rods versus cones. Human Molecular Genetics. 18: 797-808. PMID 19050038 DOI: 10.1093/hmg/ddn406  1
2008 Conley SM, Cai X, Naash MI. Nonviral ocular gene therapy: assessment and future directions. Current Opinion in Molecular Therapeutics. 10: 456-63. PMID 18830921  1
2008 Stamer WD, Chan DW, Conley SM, Coons S, Ethier CR. Aquaporin-1 expression and conventional aqueous outflow in human eyes. Experimental Eye Research. 87: 349-55. PMID 18657536 DOI: 10.1016/j.exer.2008.06.018  1
2008 Cai X, Conley S, Naash M. Nanoparticle applications in ocular gene therapy. Vision Research. 48: 319-24. PMID 17825344 DOI: 10.1016/j.visres.2007.07.012  1
2007 Conley S, Nour M, Fliesler SJ, Naash MI. Late-onset cone photoreceptor degeneration induced by R172W mutation in Rds and partial rescue by gene supplementation. Investigative Ophthalmology & Visual Science. 48: 5397-407. PMID 18055786 DOI: 10.1167/iovs.07-0663  1
2006 Conley SM, McKay BS, Gandolfi AJ, Stamer WD. Alterations in human trabecular meshwork cell homeostasis by selenium. Experimental Eye Research. 82: 637-47. PMID 16289047 DOI: 10.1016/j.exer.2005.08.024  1
2005 Hoffman EA, Conley SM, Stamer WD, McKay BS. Barriers to productive transfection of trabecular meshwork cells. Molecular Vision. 11: 869-75. PMID 16270026  1
2004 Burgess JL, Fierro MA, Lantz RC, Hysong TA, Fleming JE, Gerkin R, Hnizdo E, Conley SM, Klimecki W. Longitudinal decline in lung function: evaluation of interleukin-10 genetic polymorphisms in firefighters. Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine. 46: 1013-22. PMID 15602175 DOI: 10.1097/01.jom.0000141668.70006.52  1
2004 Conley SM, Bruhn RL, Morgan PV, Stamer WD. Selenium's effects on MMP-2 and TIMP-1 secretion by human trabecular meshwork cells. Investigative Ophthalmology & Visual Science. 45: 473-9. PMID 14744887 DOI: 10.1167/iovs.03-0767  1
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