Dan Simionescu - Publications

Bioengineering Clemson University, Clemson, SC, United States 
Biomedical Engineering

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Filippi A, Constantin A, Alexandru N, Voicu G, Constantinescu CA, Rebleanu D, Fenyo M, Simionescu D, Simionescu A, Manduteanu I, Georgescu A. Integrins α4β1 and αVβ3 are Reduced in Endothelial Progenitor Cells from Diabetic Dyslipidemic Mice and May Represent New Targets for Therapy in Aortic Valve Disease. Cell Transplantation. 29: 963689720946277. PMID 32841051 DOI: 10.1177/0963689720946277  0.64
2019 Tucureanu MM, Filippi A, Alexandru N, Ana Constantinescu C, Ciortan L, Macarie R, Vadana M, Voicu G, Frunza S, Nistor D, Simionescu A, Simionescu DT, Georgescu A, Manduteanu I. Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis. Diabetes & Vascular Disease Research. 1479164119874469. PMID 31530180 DOI: 10.1177/1479164119874469  0.64
2016 Harpa M, Movileanu I, Sierad L, Cotoi O, Suciu H, Preda T, Nistor D, Sircuta C, Brânzaniuc K, Deac R, Gurzu S, Harceaga L, Olah P, Simionescu D, Dandel M, et al. In Vivo Testing of Xenogeneic Acellular Aortic Valves Seeded with Stem Cells. Revista Romana De Medicina De Laborator. 24: 343-346. PMID 31098341 DOI: 10.1515/rrlm-2016-0031  0.64
2016 Chow JP, Simionescu DT, Carter AL, Simionescu A. Immunomodulatory effects of adipose tissue-derived stem cells on elastin scaffold remodeling in diabetes. Tissue Engineering and Regenerative Medicine. 13: 701-712. PMID 30603451 DOI: 10.1007/s13770-016-0018-x  0.64
2016 Kennamer A, Sierad L, Pascal R, Rierson N, Albers C, Harpa M, Cotoi O, Harceaga L, Olah P, Terezia P, Simionescu A, Simionescu D. Bioreactor Conditioning of Valve Scaffolds Seeded Internally with Adult Stem Cells. Tissue Engineering and Regenerative Medicine. 13: 507-515. PMID 30337944 DOI: 10.1007/s13770-016-9114-1  0.64
2016 Deborde C, Simionescu DT, Wright C, Liao J, Sierad LN, Simionescu A. Stabilized collagen and elastin-based scaffolds for mitral valve tissue engineering. Tissue Engineering. Part A. PMID 27608885 DOI: 10.1089/ten.TEA.2016.0032  0.64
2015 Sierad LN, Shaw EL, Bina A, Brazile B, Rierson N, Patnaik SS, Kennamer A, Odum R, Cotoi O, Terezia P, Branzaniuc K, Smallwood H, Deac R, Egyed I, Pavai Z, ... ... Simionescu DT, et al. Functional Heart Valve Scaffolds Obtained by Complete Decellularization of Porcine Aortic Roots in a Novel Differential Pressure Gradient Perfusion System. Tissue Engineering. Part C, Methods. PMID 26467108 DOI: 10.1089/ten.TEC.2015.0170  1
2015 Olsen TR, Mattix B, Casco M, Herbst A, Williams C, Tarasidis A, Simionescu D, Visconti RP, Alexis F. Manipulation of cellular spheroid composition and the effects on vascular tissue fusion. Acta Biomaterialia. 13: 188-98. PMID 25463485 DOI: 10.1016/j.actbio.2014.11.024  1
2015 Harpa MM, Movileanu I, Sierad LN, Cotoi OS, Suciu H, Sircuta C, Preda T, Nistor D, Branzaniuc K, Deac R, Dandel M, Gurzu S, Harceaga L, Olah P, Simionescu A, ... Simionescu D, et al. Pulmonary heart valve replacement using stabilized acellular xenogeneic scaffolds; effects of seeding with autologous stem cells Revista Romana De Medicina De Laborator. 23: 415-430. DOI: 10.1515/rrlm-2015-0046  1
2014 Pennel T, Fercana G, Bezuidenhout D, Simionescu A, Chuang TH, Zilla P, Simionescu D. The performance of cross-linked acellular arterial scaffolds as vascular grafts; pre-clinical testing in direct and isolation loop circulatory models Biomaterials. 35: 6311-6322. PMID 24816365 DOI: 10.1016/j.biomaterials.2014.04.062  1
2014 Fercana G, Bowser D, Portilla M, Langan EM, Carsten CG, Cull DL, Sierad LN, Simionescu DT. Platform technologies for decellularization, tunic-specific cell seeding, and in vitro conditioning of extended length, small diameter vascular grafts. Tissue Engineering. Part C, Methods. 20: 1016-27. PMID 24749889 DOI: 10.1089/ten.TEC.2014.0047  1
2014 Mattix BM, Olsen TR, Casco M, Reese L, Poole JT, Zhang J, Visconti RP, Simionescu A, Simionescu DT, Alexis F. Janus magnetic cellular spheroids for vascular tissue engineering. Biomaterials. 35: 949-60. PMID 24183699 DOI: 10.1016/j.biomaterials.2013.10.036  1
2014 Mattix B, Olsen TR, Gu Y, Casco M, Herbst A, Simionescu DT, Visconti RP, Kornev KG, Alexis F. Biological magnetic cellular spheroids as building blocks for tissue engineering. Acta Biomaterialia. 10: 623-9. PMID 24176725 DOI: 10.1016/j.actbio.2013.10.021  1
2014 Olsen TR, Mattix B, Casco M, Herbst A, Williams C, Tarasidis A, Evans G, Jenkins L, McMahan CL, Simionescu D, Visconti RP, Alexis F. Processing cellular spheroids for histological examination Journal of Histotechnology. 37: 138-142. DOI: 10.1179/2046023614Y.0000000047  1
2014 Mercuri J, Addington C, Pascal R, Gill S, Simionescu D. Development and initial characterization of a chemically stabilized elastin-glycosaminoglycan-collagen composite shape-memory hydrogel for nucleus pulposus regeneration Journal of Biomedical Materials Research - Part A. 102: 4380-4393. DOI: 10.1002/jbm.a.35104  1
2014 Mattix B, Olsen TR, Moore T, Casco M, Simionescu D, Visconti RP, Alexis F. Accelerated iron oxide nanoparticle degradation mediated by polyester encapsulation within cellular spheroids Advanced Functional Materials. 24: 800-807. DOI: 10.1002/adfm.201301736  1
2013 Schulte JB, Simionescu A, Simionescu DT. The acellular myocardial flap: a novel extracellular matrix scaffold enriched with patent microvascular networks and biocompatible cell niches. Tissue Engineering. Part C, Methods. 19: 518-30. PMID 23151037 DOI: 10.1089/ten.TEC.2012.0536  1
2013 Mercuri JJ, Patnaik S, Dion G, Gill SS, Liao J, Simionescu DT. Regenerative potential of decellularized porcine nucleus pulposus hydrogel scaffolds: stem cell differentiation, matrix remodeling, and biocompatibility studies. Tissue Engineering. Part A. 19: 952-66. PMID 23140227 DOI: 10.1089/ten.TEA.2012.0088  1
2013 Chow JP, Simionescu DT, Warner H, Wang B, Patnaik SS, Liao J, Simionescu A. Mitigation of diabetes-related complications in implanted collagen and elastin scaffolds using matrix-binding polyphenol. Biomaterials. 34: 685-95. PMID 23103157 DOI: 10.1016/j.biomaterials.2012.09.081  1
2012 Simionescu DT, Chen J, Jaeggli M, Wang B, Liao J. Form Follows Function: Advances in Trilayered Structure Replication for Aortic Heart Valve Tissue Engineering. Journal of Healthcare Engineering. 3: 179-202. PMID 23355946 DOI: 10.1260/2040-2295.3.2.179  1
2012 Wang B, Tedder ME, Perez CE, Wang G, de Jongh Curry AL, To F, Elder SH, Williams LN, Simionescu DT, Liao J. Structural and biomechanical characterizations of porcine myocardial extracellular matrix. Journal of Materials Science. Materials in Medicine. 23: 1835-47. PMID 22584822 DOI: 10.1007/s10856-012-4660-0  1
2012 Mercuri JJ, Simionescu DT. Advances in tissue engineering approaches to treatment of intervertebral disc degeneration: Cells and polymeric scaffolds for nucleus pulposus regeneration Advances in Polymer Science. 247: 201-231. DOI: 10.1007/12_2011_149  1
2011 Simionescu A, Tedder ME, Chuang TH, Simionescu DT. Lectin and antibody-based histochemical techniques for cardiovascular tissue engineering. Journal of Histotechnology. 34: 20-28. PMID 25620822 DOI: 10.1179/014788811X12949268296040  1
2011 Simionescu A, Schulte JB, Fercana G, Simionescu DT. Inflammation in cardiovascular tissue engineering: the challenge to a promise: a minireview. International Journal of Inflammation. 2011: 958247. PMID 21755031 DOI: 10.4061/2011/958247  0.64
2011 Mercuri JJ, Gill SS, Simionescu DT. Novel tissue-derived biomimetic scaffold for regenerating the human nucleus pulposus. Journal of Biomedical Materials Research. Part A. 96: 422-35. PMID 21171162 DOI: 10.1002/jbm.a.33001  1
2011 Ariganello MB, Simionescu DT, Labow RS, Lee JM. Macrophage differentiation and polarization on a decellularized pericardial biomaterial. Biomaterials. 32: 439-49. PMID 20933269 DOI: 10.1016/j.biomaterials.2010.09.004  1
2011 Tedder ME, Simionescu A, Chen J, Liao J, Simionescu DT. Assembly and testing of stem cell-seeded layered collagen constructs for heart valve tissue engineering. Tissue Engineering. Part A. 17: 25-36. PMID 20673028 DOI: 10.1089/ten.TEA.2010.0138  1
2010 Sierad LN, Simionescu A, Albers C, Chen J, Maivelett J, Tedder ME, Liao J, Simionescu DT. Design and Testing of a Pulsatile Conditioning System for Dynamic Endothelialization of Polyphenol-Stabilized Tissue Engineered Heart Valves. Cardiovascular Engineering and Technology. 1: 138-153. PMID 21340043 DOI: 10.1007/s13239-010-0014-6  1
2010 Wang B, Borazjani A, Tahai M, Curry AL, Simionescu DT, Guan J, To F, Elder SH, Liao J. Fabrication of cardiac patch with decellularized porcine myocardial scaffold and bone marrow mononuclear cells. Journal of Biomedical Materials Research. Part A. 94: 1100-10. PMID 20694977 DOI: 10.1002/jbm.a.32781  1
2010 Luszczyn J, Plonska-Brzezinska ME, Palkar A, Dubis AT, Simionescu A, Simionescu DT, Kalska-Szostko B, Winkler K, Echegoyen L. Small noncytotoxic carbon nano-onions: first covalent functionalization with biomolecules. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 4870-80. PMID 20340115 DOI: 10.1002/chem.200903277  1
2009 Chuang TH, Stabler C, Simionescu A, Simionescu DT. Polyphenol-stabilized tubular elastin scaffolds for tissue engineered vascular grafts. Tissue Engineering. Part A. 15: 2837-51. PMID 19254115 DOI: 10.1089/ten.TEA.2008.0394  1
2009 Tedder ME, Liao J, Weed B, Stabler C, Zhang H, Simionescu A, Simionescu DT. Stabilized collagen scaffolds for heart valve tissue engineering. Tissue Engineering. Part A. 15: 1257-68. PMID 18928400 DOI: 10.1089/ten.tea.2008.0263  1
2008 Yuan YY, Kostenuik PJ, Ominsky MS, Morony S, Adamu S, Simionescu DT, Basalyga DM, Asuncion FJ, Bateman TA. Skeletal deterioration induced by RANKL infusion: a model for high-turnover bone disease. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 19: 625-35. PMID 18038244 DOI: 10.1007/s00198-007-0509-7  1
2008 Sierad LN, Simionescu D. In vitro testing of living aortic heart valves using a pulsatile bioreactor 2008 Proceedings of the 3rd Frontiers in Biomedical Devices Conference and Exhibition. 89-90.  1
2007 Simionescu A, Simionescu DT, Vyavahare NR. Osteogenic responses in fibroblasts activated by elastin degradation products and transforming growth factor-beta1: role of myofibroblasts in vascular calcification. The American Journal of Pathology. 171: 116-23. PMID 17591959 DOI: 10.2353/ajpath.2007.060930  1
2007 Isenburg JC, Simionescu DT, Starcher BC, Vyavahare NR. Elastin stabilization for treatment of abdominal aortic aneurysms. Circulation. 115: 1729-37. PMID 17372168 DOI: 10.1161/CIRCULATIONAHA.106.672873  1
2007 Kurane A, Simionescu DT, Vyavahare NR. In vivo cellular repopulation of tubular elastin scaffolds mediated by basic fibroblast growth factor. Biomaterials. 28: 2830-8. PMID 17368531 DOI: 10.1016/j.biomaterials.2007.02.031  1
2007 Raghavan D, Simionescu DT, Vyavahare NR. Neomycin prevents enzyme-mediated glycosaminoglycan degradation in bioprosthetic heart valves. Biomaterials. 28: 2861-8. PMID 17353047 DOI: 10.1016/j.biomaterials.2007.02.017  1
2007 Simpson CL, Lindley S, Eisenberg C, Basalyga DM, Starcher BC, Simionescu DT, Vyavahare NR. Toward cell therapy for vascular calcification: osteoclast-mediated demineralization of calcified elastin. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 16: 29-37. PMID 17218212 DOI: 10.1016/j.carpath.2006.07.001  1
2007 Mercuri JJ, Lovekamp JJ, Simionescu DT, Vyavahare NR. Glycosaminoglycan-targeted fixation for improved bioprosthetic heart valve stabilization. Biomaterials. 28: 496-503. PMID 17030363 DOI: 10.1016/j.biomaterials.2006.09.005  1
2006 Isenburg JC, Karamchandani NV, Simionescu DT, Vyavahare NR. Structural requirements for stabilization of vascular elastin by polyphenolic tannins. Biomaterials. 27: 3645-51. PMID 16527345 DOI: 10.1016/j.biomaterials.2006.02.016  1
2006 Lee JS, Basalyga DM, Simionescu A, Isenburg JC, Simionescu DT, Vyavahare NR. Elastin calcification in the rat subdermal model is accompanied by up-regulation of degradative and osteogenic cellular responses. The American Journal of Pathology. 168: 490-8. PMID 16436663 DOI: 10.2353/ajpath.2006.050338  1
2006 Lovekamp JJ, Simionescu DT, Mercuri JJ, Zubiate B, Sacks MS, Vyavahare NR. Stability and function of glycosaminoglycans in porcine bioprosthetic heart valves. Biomaterials. 27: 1507-18. PMID 16144707 DOI: 10.1016/j.biomaterials.2005.08.003  1
2006 Kasyanov V, Isenburg J, Draughn RA, Hazard S, Hodde J, Ozolanta I, Murovska M, Halkes SB, Vrasidas I, Liskamp RM, Pieters RJ, Simionescu D, Markwald RR, Mironov V. Tannic acid mimicking dendrimers as small intestine submucosa stabilizing nanomordants. Biomaterials. 27: 745-51. PMID 16102811 DOI: 10.1016/j.biomaterials.2005.06.022  1
2006 Simionescu DT, Lu Q, Song Y, Lee JS, Rosenbalm TN, Kelley C, Vyavahare NR. Biocompatibility and remodeling potential of pure arterial elastin and collagen scaffolds. Biomaterials. 27: 702-13. PMID 16048731 DOI: 10.1016/j.biomaterials.2005.06.013  1
2005 Isenburg JC, Simionescu DT, Vyavahare NR. Tannic acid treatment enhances biostability and reduces calcification of glutaraldehyde fixed aortic wall. Biomaterials. 26: 1237-45. PMID 15475053 DOI: 10.1016/j.biomaterials.2004.04.034  1
2004 Simionescu DT. Prevention of calcification in bioprosthetic heart valves: challenges and perspectives. Expert Opinion On Biological Therapy. 4: 1971-85. PMID 15571459 DOI: 10.1517/14712598.4.12.1971  1
2004 Basalyga DM, Simionescu DT, Xiong W, Baxter BT, Starcher BC, Vyavahare NR. Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinases. Circulation. 110: 3480-7. PMID 15545515 DOI: 10.1161/01.CIR.0000148367.08413.E9  1
2004 Lu Q, Ganesan K, Simionescu DT, Vyavahare NR. Novel porous aortic elastin and collagen scaffolds for tissue engineering. Biomaterials. 25: 5227-37. PMID 15110474 DOI: 10.1016/j.biomaterials.2003.12.019  1
2004 Bailey M, Pillarisetti S, Jones P, Xiao H, Simionescu D, Vyavahare N. Involvement of matrix metalloproteinases and tenascin-C in elastin calcification. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 13: 146-55. PMID 15081471 DOI: 10.1016/S1054-8807(04)00009-2  1
2004 Isenburg JC, Simionescu DT, Vyavahare NR. Elastin stabilization in cardiovascular implants: improved resistance to enzymatic degradation by treatment with tannic acid. Biomaterials. 25: 3293-302. PMID 14980424 DOI: 10.1016/j.biomaterials.2003.10.001  1
2003 Simionescu DT, Lovekamp JJ, Vyavahare NR. Extracellular matrix degrading enzymes are active in porcine stentless aortic bioprosthetic heart valves. Journal of Biomedical Materials Research. Part A. 66: 755-63. PMID 12926026 DOI: 10.1002/jbm.a.10066  1
2003 Simionescu DT, Lovekamp JJ, Vyavahare NR. Degeneration of bioprosthetic heart valve cusp and wall tissues is initiated during tissue preparation: an ultrastructural study. The Journal of Heart Valve Disease. 12: 226-34. PMID 12701796  1
2003 Simionescu DT, Lovekamp JJ, Vyavahare NR. Glycosaminoglycan-degrading enzymes in porcine aortic heart valves: implications for bioprosthetic heart valve degeneration. The Journal of Heart Valve Disease. 12: 217-25. PMID 12701795  1
2001 Bracher M, Simionescu D, Simionescu A, Davies N, Human P, Zilla P. Matrix metalloproteinases and tissue valve degeneration Journal of Long-Term Effects of Medical Implants. 11: 221-230. PMID 11921665  1
1996 Simionescu A, Simionescu D, Deac R. Biochemical pathways of tissue degeneration in bioprosthetic cardiac valves: The role of matrix metalloproteinases Asaio Journal. 42. PMID 8944942  1
1996 Simionescu A, Simionescu DT, Deac RFP. Matrix metalloproteinases in the pathology of natural and bioprosthetic cardiac valves Cardiovascular Pathology. 5: 323-332. DOI: 10.1016/S1054-8807(96)00043-9  1
1995 Deac RFP, Simionescu D, Deac D. New evolution in mitral physiology and surgery: Mitral stentless pericardial valve The Annals of Thoracic Surgery. 60. PMID 7646203 DOI: 10.1016/0003-4975(95)00303-3  1
1994 Simionescu DT, Deac R, Simionescu A. Inhibition of extracellular-matrix degrading proteases in pericardial-derived cardiovascular bioprostheses Journal of Materials Science: Materials in Medicine. 5: 748-751. DOI: 10.1007/BF00120369  1
1993 Simionescu D, Simionescu A, Deac R. Detection of remnant proteolytic activities in unimplanted glutaraldehyde- treated bovine pericardium and explanted cardiac bioprostheses Journal of Biomedical Materials Research. 27: 821-829. PMID 8408112 DOI: 10.1002/jbm.820270615  1
1993 Simionescu D, Simionescu A, Deac R. Mapping of glutaraldehyde-treated bovine pericardium and tissue selection for bioprosthetic heart valves Journal of Biomedical Materials Research. 27: 697-704. PMID 8408100 DOI: 10.1002/jbm.820270602  1
1991 Simionescu DT, Kefalides NA. The biosynthesis of proteoglycans and interstitial collagens by bovine pericardial fibroblasts Experimental Cell Research. 195: 171-176. PMID 2055265 DOI: 10.1016/0014-4827(91)90513-T  1
1991 Simionescu A, Simionescu D, Deac R. Lysine-enhanced glutaraldehyde crosslinking of collagenous biomaterials Journal of Biomedical Materials Research. 25: 1495-1506. PMID 1794997  1
1989 Simionescu D, Iozzo RV, Kefalides NA. Bovine pericardial proteoglycan: Biochemical, immunochemical and ultrastructural studies Matrix. 9: 301-310. PMID 2677626  1
1988 Simionescu D, Alper R, Kefalides NA. Partial characterization of low molecular weight proteoglycan isolated from bovine parietal pericardium Biochemical and Biophysical Research Communications. 151: 480-486. PMID 3348789 DOI: 10.1016/0006-291X(88)90618-3  1
1983 Simionescu D, Simionescu M. Differentiated distribution of the cell surface charge on the alveolar-capillary unit. Characteristic paucity of anionic sites on the air-blood barrier Microvascular Research. 25: 85-100. PMID 6835101 DOI: 10.1016/0026-2862(83)90045-6  1
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