Ronald A. Siegel - Publications

Affiliations: 
Biomedical Engineering University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Biomedical Engineering, Chemical Engineering, Pharmacology

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Siegel RA, Brown L, Edelman ER, Linhardt RJ. B'reshith. Journal of Controlled Release : Official Journal of the Controlled Release Society. 285: 252-257. PMID 30078756 DOI: 10.1016/j.jconrel.2018.07.005  0.52
2017 Kim A, Lee H, Jones CF, Mujumdar SK, Gu Y, Siegel RA. Swelling, Mechanics, and Thermal/Chemical Stability of Hydrogels Containing Phenylboronic Acid Side Chains. Gels (Basel, Switzerland). 4. PMID 30674779 DOI: 10.3390/gels4010004  1
2016 Siegel RA, Kirtane AR, Panyam J. Assessing the benefits of targeted drug delivery by nanocarriers: A partico/pharmacokinetic framework. Ieee Transactions On Bio-Medical Engineering. PMID 27913319 DOI: 10.1109/TBME.2016.2632733  0.56
2016 Wang W, Siegel RA, Wang C. Nanocomposite Polymers with "slimy" Surfaces that Refresh Following Abrasion Acs Biomaterial Science and Engineering. 2: 180-187. DOI: 10.1021/acsbiomaterials.5b00182  1
2015 Siegel RA, Kapoor M, Cheryala N, Georg GI, Cloyd JC. Water-soluble benzodiazepine prodrug/enzyme combinations for intranasal rescue therapies. Epilepsy & Behavior : E&B. PMID 26115606 DOI: 10.1016/j.yebeh.2015.05.004  1
2015 Kirtane AR, Siegel RA, Panyam J. A pharmacokinetic model for quantifying the effect of vascular permeability on the choice of drug carrier: a framework for personalized nanomedicine. Journal of Pharmaceutical Sciences. 104: 1174-86. PMID 25583443 DOI: 10.1002/jps.24302  1
2014 Bhalla AS, Siegel RA. Mechanistic studies of an autonomously pulsing hydrogel/enzyme system for rhythmic hormone delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 196: 261-71. PMID 25450402 DOI: 10.1016/j.jconrel.2014.10.019  1
2014 Siegel RA. Stimuli sensitive polymers and self regulated drug delivery systems: a very partial review. Journal of Controlled Release : Official Journal of the Controlled Release Society. 190: 337-51. PMID 24984012 DOI: 10.1016/j.jconrel.2014.06.035  1
2014 Kapoor M, Winter T, Lis L, Georg GI, Siegel RA. Rapid delivery of diazepam from supersaturated solutions prepared using prodrug/enzyme mixtures: toward intranasal treatment of seizure emergencies. The Aaps Journal. 16: 577-85. PMID 24700272 DOI: 10.1208/s12248-014-9596-5  1
2014 Song SH, Park JH, Chitnis G, Siegel RA, Ziaie B. A wireless chemical sensor featuring iron oxidenanoparticle-embedded hydrogels Sensors and Actuators, B: Chemical. 193: 925-930. DOI: 10.1016/j.snb.2013.12.012  1
2013 Kapoor M, Siegel RA. Prodrug/Enzyme based acceleration of absorption of hydrophobic drugs: an in vitro study. Molecular Pharmaceutics. 10: 3519-24. PMID 23937162 DOI: 10.1021/mp400272m  1
2013 Park JH, Song SH, Chitnis G, Siegel RA, Ziaie B. A wireless chemical sensor using ferroparticles embedded hydrogel 2013 Transducers and Eurosensors Xxvii: the 17th International Conference On Solid-State Sensors, Actuators and Microsystems, Transducers and Eurosensors 2013. 1735-1738. DOI: 10.1109/Transducers.2013.6627122  1
2013 Khandai S, Siegel RA, Jena SS. Probing the microstructure of hydrogels using fluorescence recovery after photobleaching Aip Conference Proceedings. 1512: 134-135. DOI: 10.1063/1.4790947  1
2012 Khushf G, Siegel RA. What is unique about nanomedicine? The significance of the mesoscale. The Journal of Law, Medicine & Ethics : a Journal of the American Society of Law, Medicine & Ethics. 40: 780-94. PMID 23289680 DOI: 10.1111/j.1748-720X.2012.00706.x  1
2012 Fatehi L, Wolf SM, McCullough J, Hall R, Lawrenz F, Kahn JP, Jones C, Campbell SA, Dresser RS, Erdman AG, Haynes CL, Hoerr RA, Hogle LF, Keane MA, Khushf G, ... ... Siegel RA, et al. Recommendations for nanomedicine human subjects research oversight: an evolutionary approach for an emerging field. The Journal of Law, Medicine & Ethics : a Journal of the American Society of Law, Medicine & Ethics. 40: 716-50. PMID 23289677 DOI: 10.1111/j.1748-720X.2012.00703.x  1
2012 Koonar I, Zhou C, Hillmyer MA, Lodge TP, Siegel RA. ABC triblock terpolymers exhibiting both temperature- and pH-sensitive micellar aggregation and gelation in aqueous solution. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 17785-94. PMID 23189918 DOI: 10.1021/la303712b  1
2012 Feldstein MM, Siegel RA. Molecular and nanoscale factors governing pressure-sensitive adhesion strength of viscoelastic polymers Journal of Polymer Science, Part B: Polymer Physics. 50: 739-772. DOI: 10.1002/polb.23065  1
2011 Motion JP, Huynh GH, Szoka FC, Siegel RA. Convection and retro-convection enhanced delivery: some theoretical considerations related to drug targeting. Pharmaceutical Research. 28: 472-9. PMID 20963628 DOI: 10.1007/s11095-010-0296-2  1
2011 Feldstein MM, Bermesheva EV, Jean YC, Misra GP, Siegel RA. Free volume, adhesion, and viscoelastic properties of model nanostructured pressure-sensitive adhesive based on stoichiometric complex of poly(N-vinyl pyrrolidone) and poly(ethylene glycol) of disparate chain lengths Journal of Applied Polymer Science. 119: 2408-2421. DOI: 10.1002/app.32917  1
2010 Siegel RA, Linstad JL. Cooperative binding isotherms for nearest neighbor interacting ligands on platonic solids: a simple model for viral capture nanotherapy. The Journal of Physical Chemistry. B. 114: 14071-6. PMID 20949931 DOI: 10.1021/jp1066378  1
2010 Vermonden T, Jena SS, Barriet D, Censi R, van der Gucht J, Hennink WE, Siegel RA. Macromolecular Diffusion in Self-Assembling Biodegradable Thermosensitive Hydrogels. Macromolecules. 43: 782-789. PMID 20885989 DOI: 10.1021/ma902186e  1
2010 Xie Y, Zeng P, Siegel RA, Wiedmann TS, Hammer BE, Longest PW. Magnetic deposition of aerosols composed of aggregated superparamagnetic nanoparticles. Pharmaceutical Research. 27: 855-65. PMID 20198407 DOI: 10.1007/s11095-010-0078-x  1
2010 Xu F, Liu G, Zhang Q, Siegel RA. A comparative study on two phenylboronic acid based glucose-sensitive hydrogels. Frontiers in Bioscience (Elite Edition). 2: 657-67. PMID 20036909  1
2010 Siegel RA, Gu Y, Lei M, Baldi A, Nuxoll EE, Ziaie B. Hard and soft micro- and nanofabrication: An integrated approach to hydrogel-based biosensing and drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 141: 303-13. PMID 20036310 DOI: 10.1016/j.jconrel.2009.12.012  1
2010 Siegel RA. Oscillatory Systems Created with Polymer Membranes Nonlinear Dynamics With Polymers: Fundamentals, Methods and Applications. 189-217. DOI: 10.1002/9783527632602.ch10  1
2009 Nuxoll EE, Hillmyer MA, Wang R, Leighton C, Siegel RA. Composite block polymer-microfabricated silicon nanoporous membrane. Acs Applied Materials & Interfaces. 1: 888-93. PMID 20160882 DOI: 10.1021/am900013v  1
2009 Siegel RA, Nuxoll EE, Hillmyer MA, Ziaie B. Top-down and bottom-up fabrication techniques for hydrogel based sensing and hormone delivery microdevices. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 232-5. PMID 19963454 DOI: 10.1109/IEMBS.2009.5332511  1
2009 Ivaturi VD, Riss JR, Kriel RL, Siegel RA, Cloyd JC. Bioavailability and tolerability of intranasal diazepam in healthy adult volunteers. Epilepsy Research. 84: 120-6. PMID 19231138 DOI: 10.1016/j.eplepsyres.2009.01.001  1
2009 Nuxoll EE, Siegel RA. BioMEMS devices for drug delivery. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 28: 31-9. PMID 19150769 DOI: 10.1109/MEMB.2008.931014  1
2009 Lei M, Baldi A, Nuxoll E, Siegel RA, Ziaie B. Hydrogel-based microsensors for wireless chemical monitoring. Biomedical Microdevices. 11: 529-38. PMID 18335316 DOI: 10.1007/s10544-008-9168-5  1
2009 Gu Y, Dhanarajan AP, Hruby SL, Baldi A, Ziaie B, Siegel RA. An interpenetrating glass-thermosensitive hydrogel construct. Gated flow control and thermofluidic oscillations Sensors and Actuators, B: Chemical. 138: 631-636. DOI: 10.1016/j.snb.2009.02.044  1
2009 Siegel RA. Autonomous rhythmic drug delivery systems based on chemical and biochemomechanical oscillators Nato Science For Peace and Security Series a: Chemistry and Biology. 175-201. DOI: 10.1007/978-90-481-2993-5-7  1
2008 Mujumdar SK, Siegel RA. Introduction of pH-Sensitivity into Mechanically Strong Nanoclay Composite Hydrogels Based on N-Isopropylacrylamide. Journal of Polymer Science. Part a, Polymer Chemistry. 46: 6630-6640. PMID 19802380 DOI: 10.1002/pola.22973  1
2008 Varigonda S, Georgiou TT, Siegel RA, Daoutidis P. Optimal periodic control of a drug delivery system Computers and Chemical Engineering. 32: 2256-2262. DOI: 10.1016/j.compchemeng.2007.11.003  1
2008 Bayramov DF, Singh P, Cleary GW, Siegel RA, Chalykh AE, Feldstein MM. Non-covalently crosslinked hydrogels displaying a unique combination of water-absorbing, elastic and adhesive properties Polymer International. 57: 785-790. DOI: 10.1002/pi.2417  1
2008 Bhalla AS, Mujumdar S, Siegel RA. Factors governing glucose-driven pH oscillations in a hydrogel-enzyme- marble reactor American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. 49: 769-770.  1
2007 Lei M, Ziaie B, Nuxoll E, Iván K, Noszticzius Z, Siegel RA. Integration of hydrogels with hard and soft microstructures. Journal of Nanoscience and Nanotechnology. 7: 780-9. PMID 17450833 DOI: 10.1166/jnn.2007.513  1
2007 Siegel RA. Investigation of a cellular pharmacodynamic model exhibiting sharp response sensitivity and tolerance. Journal of Pharmacokinetics and Pharmacodynamics. 34: 87-101. PMID 17160695 DOI: 10.1007/s10928-006-9042-0  1
2007 Mujumdar SK, Bhalla AS, Siegel RA. Novel hydrogels for rhythmic pulsatile drug delivery Macromolecular Symposia. 254: 338-344. DOI: 10.1002/masy.200750849  1
2006 Liang W, Siegel RA. Theoretical and experimental exploration of rules for combining transport parameters in laminar membranes. The Journal of Chemical Physics. 125: 44707. PMID 16942174 DOI: 10.1063/1.2216691  1
2006 Carlson JC, Jena SS, Flenniken M, Chou TF, Siegel RA, Wagner CR. Chemically controlled self-assembly of protein nanorings. Journal of the American Chemical Society. 128: 7630-8. PMID 16756320 DOI: 10.1021/ja060631e  1
2006 Hou H, Siegel RA. Enhanced permeation of diazepam through artificial membranes from supersaturated solutions. Journal of Pharmaceutical Sciences. 95: 896-905. PMID 16493587 DOI: 10.1002/jps.20600  1
2006 Lei M, Baldi A, Nuxoll E, Siegel RA, Ziaie B. A hydrogel-based implantable micromachined transponder for wireless glucose measurement. Diabetes Technology & Therapeutics. 8: 112-22. PMID 16472058 DOI: 10.1089/dia.2006.8.112  1
2006 Baldi A, Lei M, Gu Y, Siegel RA, Ziaie B. A microstructured silicon membrane with entrapped hydrogels for environmentally sensitive fluid gating Sensors and Actuators, B: Chemical. 114: 9-18. DOI: 10.1016/j.snb.2005.04.020  1
2005 Siegel RA, Ramanathan M. Commentary: stochastic phenomena in pharmacokinetic, pharmacodynamic and pharmacogenomic models. The Aaps Journal. 7: E141-2. PMID 16493838 DOI: 10.1208/aapsj070114  1
2005 Siegel RA. Characterization of relaxation to steady state in membranes with binding and reaction Journal of Membrane Science. 251: 91-99. DOI: 10.1016/j.memsci.2004.10.039  1
2005 Nuxoll EE, Siegel RA, Cussler EL. Layered reactive barrier films Journal of Membrane Science. 252: 29-36. DOI: 10.1016/j.memsci.2004.06.063  1
2005 Dhanarajan AP, Siege RA. Time-dependent permeabilities of hydrophobic, pH-sensitive hydrogels exposed to pH gradients Macromolecular Symposia. 227: 105-114. DOI: 10.1002/masy.200550910  1
2005 Lei M, Choi W, Siegel RA, Ziaie B. An ultrasensitive chemical microsensor based on self-aligned dry-patterned environmentally sensitive hydrogels Digest of Technical Papers - International Conference On Solid State Sensors and Actuators and Microsystems, Transducers '05. 2: 1824-1827.  1
2005 Kawabata K, Tuji S, Siegel RA, Kawaguchi H. Preparation of hairy particle having PHEMA hear and their characterization Polymer Preprints, Japan. 54: 1033.  1
2005 Kawabat K, Tsuji S, Siegel RA, Kawaguchi H. Preparation of hairy particles by graft polymerization of HEMA and colloidal properties of resulting hairy particles Polymer Preprints, Japan. 54: 3824-3825.  1
2004 Ziaie B, Siegel RA. Hydrogel-Based BioMEMS platforms for smart drug delivery. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 4: 2670. PMID 17511110  0.64
2004 Lei M, Gu Y, Baldi A, Siegel RA, Ziaie B. High-resolution technique for fabricating environmentally sensitive hydrogel microstructures. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 8947-51. PMID 15461469 DOI: 10.1021/la048719y  1
2004 Ziaie B, Baldi A, Lei M, Gu Y, Siegel RA. Hard and soft micromachining for BioMEMS: review of techniques and examples of applications in microfluidics and drug delivery. Advanced Drug Delivery Reviews. 56: 145-72. PMID 14741113 DOI: 10.1016/j.addr.2003.09.001  1
2004 Siegel RA, Ziaie B. Biosensing and drug delivery at the microscale. Advanced Drug Delivery Reviews. 56: 121-3. PMID 14741111 DOI: 10.1016/j.addr.2003.10.001  1
2004 Siegel RA, Cussler EL. Reactive barrier membranes: Some theoretical observations regarding the time lag and breakthrough curves Journal of Membrane Science. 229: 33-41. DOI: 10.1016/j.memsci.2003.10.013  1
2004 Siegel RA, Gu Y, Baldi A, Ziaie B. Novel swelling/shrinking behaviors of glucose-binding hydrogels and their potential use in a microfluidic insulin delivery system Macromolecular Symposia. 207: 249-256. DOI: 10.1002/masy.200450322  1
2004 Siegel RA, Licea-Claveríe A, Grosberg A. Fundamentals and applications of polymer gels: PPF-7 microsymposium, Oaxaca City, Mexico December 5-7, 2001. Preface Macromolecular Symposia. 207.  1
2004 Dhanarajan AP, Urban J, Siegel RA. A model for a hydrogel-enzyme chemomechanical oscillator Acs Symposium Series. 869: 44-57.  1
2004 Lei M, Salim A, Siegel RA, Ziaie B. A hydrogel-actuated microvalve for smart flow control Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 26: 2041-2044.  1
2004 Lei M, Gu Y, Baldi A, Siegel RA, Ziaie B. Soft mold-dry etch: A novel hydrogel patterning technique for biomedical applications Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 26: 1983-1986.  1
2004 Lei M, Baldi A, Pan T, Gu Y, Siegel RA, Ziaie B. A hydrogel-based wireless chemical sensor Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 391-394.  1
2003 Rosner BI, Siegel RA, Grosberg A, Tranquillo RT. Rational design of contact guiding, neurotrophic matrices for peripheral nerve regeneration. Annals of Biomedical Engineering. 31: 1383-401. PMID 14758929 DOI: 10.1114/1.1626118  1
2003 Baldi A, Gu Y, Loftness PE, Siegel RA, Ziaie B. A hydrogel-actuated environmentally sensitive microvalve for active flow control Journal of Microelectromechanical Systems. 12: 613-621. DOI: 10.1109/JMEMS.2003.818070  1
2003 Baldi A, Lei M, Gu Y, Siegel RA, Ziaie B. An environmentally responsive microflow controller with double side tethered structure for the entrapment of hydrogel Proceedings of the Ieee Micro Electro Mechanical Systems (Mems). 84-87.  1
2002 Misra GP, Siegel RA. Ionizable drugs and pH oscillators: buffering effects. Journal of Pharmaceutical Sciences. 91: 2003-15. PMID 12210047 DOI: 10.1002/jps.10189  1
2002 Misra GP, Siegel RA. New mode of drug delivery: long term autonomous rhythmic hormone release across a hydrogel membrane. Journal of Controlled Release : Official Journal of the Controlled Release Society. 81: 1-6. PMID 11992673 DOI: 10.1016/S0168-3659(02)00043-3  1
2002 Misra GP, Siegel RA. Multipulse drug permeation across a membrane driven by a chemical pH-oscillator. Journal of Controlled Release : Official Journal of the Controlled Release Society. 79: 293-7. PMID 11853939 DOI: 10.1016/S0168-3659(01)00523-5  1
2002 Gu Y, Baldi A, Ziaie B, Siegel RA. Modulation of drug delivery rate by hydrogel-incorporating MEMS devices 2nd Annual International Ieee-Embs Special Topic Conference On Microtechnologies in Medicine and Biology - Proceedings. 406-409. DOI: 10.1109/MMB.2002.1002356  1
2002 Dhanarajan AP, Misra GP, Siegel RA. Autonomous chemomechanical oscillations in a hydrogel/enzyme system driven by glucose Journal of Physical Chemistry A. 106: 8835-8838. DOI: 10.1021/jp026086v  1
2002 Bairamov DF, Chalykh AE, Feldstein MM, Siegel RA. Impact of molecular weight on miscibility and interdiffusion between poly(N-vinyl pyrrolidone) and poly(ethylene glycol) Macromolecular Chemistry and Physics. 203: 2674-2685. DOI: 10.1002/macp.200290050  1
2002 Bairamov DF, Chalykh AE, Feldstein MM, Siegel RA, Plate NA. Dissolution and mutual diffusion of poly(N-vinyl pyrrolidone) in short-chain poly(ethylene glycol) as observed by optical wedge microinterferometry Journal of Applied Polymer Science. 85: 1128-1136. DOI: 10.1002/app.10635  1
2002 Baldi A, Gu Y, Loftness PE, Siegel RA, Ziaie B. A hydrogel-actuated smart microvalve with a porous diffusion barrier back-plate for active flow control Proceedings of the Ieee Micro Electro Mechanical Systems (Mems). 105-108.  1
2000 Li B, Siegel RA. Global analysis of a model pulsing drug delivery oscillator based on chemomechanical feedback with hysteresis. Chaos (Woodbury, N.Y.). 10: 682-690. PMID 12779418 DOI: 10.1063/1.1286998  1
2000 Siegel RA. Theoretical analysis of inward hemispheric release above and below drug solubility Journal of Controlled Release. 69: 109-126. PMID 11018550 DOI: 10.1016/S0168-3659(00)00292-3  1
2000 Stanley GB, Poolla K, Siegel RA. Threshold modeling of autonomic control of heart rate variability. Ieee Transactions On Bio-Medical Engineering. 47: 1147-53. PMID 11008415 DOI: 10.1109/10.867918  1
2000 Siegel RA, Misra GP. Pulsing gels for episodic drug delivery: Autonomous chemomechanical feedback oscillations in a gel/enzyme system American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. 41: 705-706.  1
1999 Leroux JC, Siegel RA. Autonomous gel/enzyme oscillator fueled by glucose: Preliminary evidence for oscillations. Chaos (Woodbury, N.Y.). 9: 267-275. PMID 12779824 DOI: 10.1063/1.166403  1
1999 Leroux JC, Siegel RA. pH-Hysteresis of Glucose Permeability in Acid-Doped LCST Hydrogels: A Basis for Pulsatile Oscillatory Drug Release Acs Symposium Series. 728: 98-111.  1
1999 Zou X, Siegel RA. Modeling of oscillatory dynamics of a simple enzyme-diffusion system with hysteresis. The case of lumped permeabilities Journal of Chemical Physics. 110: 2267-2279.  1
1999 Chalykh AE, Chalykh AA, Feldstein MM, Siegel RA. Isotherms of water sorption with the blends of poly(N-vinyl pyrrolidone) - poly(ethylene glycol) Proceedings of the Controlled Release Society. 389-390.  1
1999 Feldstein MM, Chalykh AE, Chalykh AA, Fleischer G, Siegel RA, Plate NA. Fundamentals of tailoring adhesive and transport properties of polymer materials for controlled drug delivery Proceedings of the Controlled Release Society. 180-181.  1
1998 Siegel RA. A lesson from secretory granules Nature. 394: 427-428. PMID 9697762 DOI: 10.1038/28756  1
1998 Siegel RA, Zahn JL. Drug buffering effects on pulsed delivery based on chemical pH-oscillatorsS. Modeling studies Proceedings of the Controlled Release Society. 192-193.  1
1997 Shafikhani S, Siegel RA, Ferrari E, Schellenberger V. Generation of large libraries of random mutants in Bacillus subtills by PCR-based plasmid multimerization Biotechniques. 23: 304-310. PMID 9266088  1
1997 Lindfors L, Siegel RA. Osmotic swelling and deswelling of dextran gels Proceedings of the Controlled Release Society. 173-174.  1
1997 Zou X, Leroux JC, Baker JP, Siegel RA. pH-hysteresis of glucose permeability in acid-doped LCST hydrogels - a basis for pulsatile, oscillatory drug release Polymeric Materials Science and Engineering, Proceedings of the Acs Division of Polymeric Materials Science and Engineering. 76: 444-445.  1
1997 Stanley G, Verotta D, Craft N, Siegel RA, Schwartz JB. Age effects on interrelationships between lung volume and heart rate during standing American Journal of Physiology - Heart and Circulatory Physiology. 42.  1
1997 Stanley G, Verotta D, Craft N, Siegel RA, Schwartz JB. Age effects on interrelationships between lung volume and heart rate during standing American Journal of Physiology - Heart and Circulatory Physiology. 42: H2128-H2134.  1
1996 Stanley G, Verotta D, Craft N, Siegel RA, Schwartz JB. Age and autonomic effects on interrelationships between lung volume and heart rate. The American Journal of Physiology. 270: H1833-40. PMID 8928893  1
1996 Cornejo-Bravo JM, Siegel RA. Water vapour sorption behaviour of copolymers of N,N-diethylaminoethyl methacrylate and methyl methacrylate Biomaterials. 17: 1187-1193. PMID 8799503 DOI: 10.1016/0142-9612(96)84939-8  1
1996 Orkisz MJ, Siegel RA. Direct Method for Measuring Shear Modulus in Gels Polymer Gels and Networks. 4: 241-252. DOI: 10.1016/0966-7822(96)00009-3  1
1996 Siegel RA. Equations for inward hemispheric release below drug solubility Proceedings of the Controlled Release Society. 117-118.  1
1996 Prevysh VA, Siegel RA. Swelling behavior of polyhydroxyethyl methacrylate gels in sodium salicylate solutions Proceedings of the Controlled Release Society. 725-726.  1
1996 Baker JP, Siegel RA. Hysteresis in the glucose permeability versus pH characteristic for a responsive hydrogel membrane Macromolecular Rapid Communications. 17: 409-415.  1
1996 Siegel RA, Zou X, Baker JP. Periodic pulsatile delivery based on membrane hysteresis: Theory Proceedings of the Controlled Release Society. 115-116.  1
1995 Cornejo-Bravo JM, Arias-Sanchez V, Alvarez-Anguiano A, Siegel RA. Kinetics of drug release from hydrophobic polybasic gels: effect of buffer acidity Journal of Controlled Release. 33: 223-229. DOI: 10.1016/0168-3659(94)00086-A  1
1995 Siegel RA, Pitt CG. A strategy for oscillatory drug release general scheme and simplified theory Journal of Controlled Release. 33: 173-188. DOI: 10.1016/0168-3659(94)00082-6  1
1995 Siegel RA. Membrane-based oscillatory drug delivery-Models Proceedings of the Controlled Release Society. 109-110.  1
1995 Siegel RA. Comments on time lags and dynamic delays in diffusion/reaction systems Journal of Physical Chemistry. 99: 17294-17296.  1
1995 Baker JP, Siegel RA. Poly(N-isopropylacrylamide) hydrogel membranes for pulsatile drug delivery Proceedings of the Controlled Release Society. 340-341.  1
1995 Orkisz MJ, Siegel RA. Direct method for measuring the shear modulus in gels Proceedings of the Controlled Release Society. 356-357.  1
1994 Firestone BA, Siegel RA. pH, salt, and buffer dependent swelling in ionizable copolymer gels: Tests of the ideal Donnan equilibrium theory Journal of Biomaterials Science, Polymer Edition. 5: 433-450. PMID 8038138 DOI: 10.1163/156856294X00130  1
1994 Oh SY, Siegel RA. Study of the dilute solution properties of poly(acrylamide-co-methyl methacrylate) Journal of Macromolecular Science, Part A. 31: 231-247. DOI: 10.1080/10601329409349730  1
1994 Cornejo-Bravo JM, Alvarez-Anguiano A, Arias-Sanchez V, Siegel RA. Buffer effect on drug release from hydrophobic polybasis gels Proceedings of the Controlled Release Society. 762-763.  1
1993 Schellenberger V, Siegel RA, Rutter WJ. Analysis of enzyme specificity by multiple substrate kinetics. Biochemistry. 32: 4344-8. PMID 8476864  1
1993 Siegel RA. Hydrophobic weak polyelectrolyte gels: Studies of swelling equilibria and kinetics Advances in Polymer Science. 109: 233-267.  1
1993 Siegel RA, Pitt CG. Strategy for sustained periodic drug delivery Proceedings of the Controlled Release Society. 49-50.  1
1992 Siegel RA, Johannes I, Hunt CA, Firestone BA. Buffer Effects on Swelling Kinetics in Polybasic Gels Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 9: 76-81. PMID 1589413 DOI: 10.1023/A:1018983828027  1
1992 Siegel RA. Commentary on "neural networks in pharmacodynamic modeling. Is current modeling practice of complex kinetic systems at a dead end?" Journal of Pharmacokinetics and Biopharmaceutics. 20: 413-416. DOI: 10.1007/BF01062466  1
1992 Sassi AP, Beltrán S, Hooper HH, Blanch HW, Prausnitz J, Siegel RA. Monte Carlo simulations of hydrophobic weak polyelectrolytes: Titration properties and pH-induced structural transitions for polymers containing weak electrolytes The Journal of Chemical Physics. 97: 8767-8774.  1
1991 Siegel RA, MacGregor RD, Hunt CA. Comparison and critique of two models for regional drug delivery Journal of Pharmacokinetics and Biopharmaceutics. 19: 363-373. PMID 1875288 DOI: 10.1007/BF03036257  1
1991 Pamela De Moor C, Doh L, Siegel RA. Long-term structural changes in pH-sensitive hydrogels Biomaterials. 12: 836-840. PMID 1764554 DOI: 10.1016/0142-9612(91)90071-H  1
1991 Firestone BA, Siegel RA. Kinetics and mechanisms of water sorption in hydrophobic, ionizable copolymer gels Journal of Applied Polymer Science. 43: 901-914. DOI: 10.1002/app.1991.070430507  1
1991 Siegel RA. Algebraic, differential, and integral relations for membranes in series and other multilaminar media: Permeabilities, solute consumption, lag times, and mean first passage times Journal of Physical Chemistry. 95: 2556-2565.  1
1990 Siegel RA, Langer R. Mechanistic studies of macromolecular drug release from macroporous polymers. II. Models for the slow kinetics of drug release Journal of Controlled Release. 14: 153-167. DOI: 10.1016/0168-3659(90)90152-J  1
1990 Siegel RA, Firestone BA. Mechanochemical approaches to self-regulating insulin pump design Journal of Controlled Release. 11: 181-192. DOI: 10.1016/0168-3659(90)90131-C  1
1990 Siegel RA, Firestone BA, Johannes I, Cornejo J. Weak ionic hydrogels. Effects of pH, ionic strength, and buffer composition on swelling equilibria, kinetics, and solute release American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. 31: 231-232.  1
1989 Siegel RA, Colburn HS. Binaural processing of noisy stimuli: internal/external noise ratios for diotic and dichotic stimuli. The Journal of the Acoustical Society of America. 86: 2122-8. PMID 2600302 DOI: 10.1121/1.398472  1
1989 Siegel RA, Kost J, Langer R. Mechanistic studies of macromolecular drug release from macroporous polymers. I. Experiments and preliminary theory concerning completeness of drug release Journal of Controlled Release. 8: 223-236. DOI: 10.1016/0168-3659(89)90044-8  1
1988 Siegel RA. Commentary to "linear and nonlinear system approaches in pharmacokinetics. How much do they have to offer? I. General considerations" Journal of Pharmacokinetics and Biopharmaceutics. 16: 667-672. PMID 3251035 DOI: 10.1007/BF01062017  1
1988 Veng-Pedersen P, Siegel RA, Boxenbaum H, Metzler CM. Linear and nonlinear system approaches in pharmacokinetics: How much do they have to offer? II. The response mapping operator (RMO) approach Journal of Pharmacokinetics and Biopharmaceutics. 16: 543-571. PMID 3199318 DOI: 10.1007/BF01062384  1
1988 Siegel RA, Falamarzian M, Firestone BA, Moxley BC. pH-Controlled release from hydrophobic/polyelectrolyte copolymer hydrogels Journal of Controlled Release. 8: 179-182. DOI: 10.1016/0168-3659(88)90044-2  1
1987 Siegel RA, Schoenwald RD. Note on "a general relationship between concentration, time and the total mass transport through a membrane" Journal of Controlled Release. 5: 193-195. DOI: 10.1016/0168-3659(87)90011-3  1
1986 Siegel RA. Pharmacokinetic transfer functions and generalized clearances Journal of Pharmacokinetics and Biopharmaceutics. 14: 511-521. PMID 3806373 DOI: 10.1007/BF01059658  1
1986 Siegel RA. The urinary elimination 'time lag': Determination of the mean residence time from drug accumulation in the urine during infusion Journal of Pharmaceutical Sciences. 75: 627-628. PMID 3735112  1
1986 Hunt CA, MacGregor RD, Siegel RA. Engineering Targeted In Vivo Drug Delivery. I. The Physiological and Physicochemical Principles Governing Opportunities and Limitations Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 3: 333-344. DOI: 10.1023/A:1016332023234  1
1986 Siegel RA. A laplace transform technique for calculating diffusion time lags Journal of Membrane Science. 26: 251-262. DOI: 10.1016/S0376-7388(00)82110-9  1
1986 Siegel RA, Langert R. A new Monte Carlo approach to diffusion in constricted porous geometries Journal of Colloid and Interface Science. 109: 426-440. DOI: 10.1016/0021-9797(86)90320-6  1
1985 Balazs AC, Calef DF, Deutch JM, Siegel RA, Langer R. The role of polymer matrix structure and interparticle interactions in diffusion-limited drug release. Biophysical Journal. 47: 97-104. PMID 3978194 DOI: 10.1016/S0006-3495(85)83881-9  1
1984 Cohen J, Siegel RA, Langer R. Sintering technique for the preparation of polymer matrices for the controlled release of macromolecules Journal of Pharmaceutical Sciences. 73: 1034-1037. PMID 6491905  1
1984 Siegel RA, Langer R. Controlled Release of Polypeptides and Other Macromolecules Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 1: 2-10. DOI: 10.1023/A:1016318423563  1
1983 Siegel RA, Colburn HS. Internal and external noise in binaural detection. Hearing Research. 11: 117-23. PMID 6619000 DOI: 10.1016/0378-5955(83)90074-6  1
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