Aleksander Skardal, Ph.D. - Publications

Affiliations: 
2010 Bioengineering University of Utah, Salt Lake City, UT 
Area:
Biomedical Engineering

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dedhia PH, Sivakumar H, Rodriguez MA, Nairon KG, Zent JM, Zheng X, Jones K, Popova LV, Leight JL, Skardal A. A 3D adrenocortical carcinoma tumor platform for preclinical modeling of drug response and matrix metalloproteinase activity. Scientific Reports. 13: 15508. PMID 37726363 DOI: 10.1038/s41598-023-42659-0  0.317
2023 Dedhia PH, Sivakumar H, Rodriguez MA, Nairon KG, Zent JM, Zheng X, Jones K, Popova L, Leight JL, Skardal A. A 3D adrenocortical carcinoma tumor platform for preclinical modeling of drug response and matrix metalloproteinase activity. Biorxiv : the Preprint Server For Biology. PMID 36747748 DOI: 10.1101/2023.01.24.525287  0.328
2022 Nairon KG, DePalma TJ, Zent JM, Leight JL, Skardal A. Tumor cell-conditioned media drives collagen remodeling via fibroblast and pericyte activation in an premetastatic niche model. Iscience. 25: 104645. PMID 35811850 DOI: 10.1016/j.isci.2022.104645  0.309
2022 Baltazar T, Kajave NS, Rodriguez M, Chakraborty S, Jiang B, Skardal A, Kishore V, Pober JS, Albanna MZ. Native human collagen type I provides a viable physiologically relevant alternative to xenogeneic sources for tissue engineering applications: A comparative in vitro and in vivo study. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. PMID 35532208 DOI: 10.1002/jbm.b.35080  0.345
2021 Mazzocchi A, Yoo KM, Nairon K, Kirk LM, Rahbar E, Soker S, Skardal A. Exploiting maleimide-functionalized hyaluronan hydrogels to test cellular responses to physical and biochemical stimuli. Biomedical Materials (Bristol, England). PMID 34937006 DOI: 10.1088/1748-605X/ac45eb  0.323
2021 DePalma TJ, Sivakumar H, Skardal A. Strategies for developing complex multi-component in vitro tumor models: Highlights in glioblastoma. Advanced Drug Delivery Reviews. 180: 114067. PMID 34822927 DOI: 10.1016/j.addr.2021.114067  0.318
2021 Yoo KM, Murphy SV, Skardal A. A Rapid Crosslinkable Maleimide-Modified Hyaluronic Acid and Gelatin Hydrogel Delivery System for Regenerative Applications. Gels (Basel, Switzerland). 7. PMID 33535669 DOI: 10.3390/gels7010013  0.347
2021 Lu Z, Priya Rajan SA, Song Q, Zhao Y, Wan M, Aleman J, Skardal A, Bishop C, Atala A, Lu B. 3D scaffold-free microlivers with drug metabolic function generated by lineage-reprogrammed hepatocytes from human fibroblasts. Biomaterials. 269: 120668. PMID 33461059 DOI: 10.1016/j.biomaterials.2021.120668  0.3
2020 Sivakumar H, Devarasetty M, Kram DE, Strowd RE, Skardal A. Multi-Cell Type Glioblastoma Tumor Spheroids for Evaluating Sub-Population-Specific Drug Response. Frontiers in Bioengineering and Biotechnology. 8: 538663. PMID 33042963 DOI: 10.3389/Fbioe.2020.538663  0.357
2020 Rajan SAP, Skardal A, Hall AR. Multi-Domain Photopatterned 3D Tumor Constructs in a Micro-Physiological System for Analysis, Quantification, and Isolation of Infiltrating Cells. Advanced Biosystems. 4: e1900273. PMID 32293164 DOI: 10.1002/adbi.201900273  0.311
2020 Maloney E, Clark C, Sivakumar H, Yoo K, Aleman J, Rajan SAP, Forsythe S, Mazzocchi A, Laxton AW, Tatter SB, Strowd RE, Votanopoulos KI, Skardal A. Immersion Bioprinting of Tumor Organoids in Multi-Well Plates for Increasing Chemotherapy Screening Throughput. Micromachines. 11. PMID 32085455 DOI: 10.3390/mi11020208  0.311
2020 Rajan SAP, Aleman J, Wan M, Zarandi NP, Nzou G, Murphy S, Bishop CE, Sadri-Ardekani H, Shupe T, Atala A, Hall AR, Skardal A. Probing prodrug metabolism and reciprocal toxicity with an integrated and humanized multi-tissue organ-on-a-chip platform. Acta Biomaterialia. PMID 32068138 DOI: 10.1016/J.Actbio.2020.02.015  0.413
2020 Bedell ML, Melchiorri AJ, Aleman J, Skardal A, Mikos AG. A high-throughput approach to compare the biocompatibility of candidate bioink formulations Bioprinting. 17: e00068. DOI: 10.1016/J.Bprint.2019.E00068  0.411
2019 Mazzocchi A, Soker S, Skardal A. 3D bioprinting for high-throughput screening: Drug screening, disease modeling, and precision medicine applications. Applied Physics Reviews. 6. PMID 33738018 DOI: 10.1063/1.5056188  0.327
2019 Mazzocchi A, Devarasetty M, Herberg S, Petty WJ, Marini F, Miller L, Kucera G, Dukes DK, Ruiz J, Skardal A, Soker S. Pleural Effusion Aspirate for use in 3D Lung Cancer Modeling and Chemotherapy Screening. Acs Biomaterials Science & Engineering. 5: 1937-1943. PMID 31723594 DOI: 10.1021/Acsbiomaterials.8B01356  0.398
2019 Aleman J, George SK, Herberg S, Devarasetty M, Porada CD, Skardal A, Almeida-Porada G. Deconstructed Microfluidic Bone Marrow On-A-Chip to Study Normal and Malignant Hemopoietic Cell-Niche Interactions. Small (Weinheim An Der Bergstrasse, Germany). e1902971. PMID 31464364 DOI: 10.1002/Smll.201902971  0.402
2019 Murphy SV, Skardal A, Nelson RA, Sunnon K, Reid T, Clouse C, Kock ND, Jackson J, Soker S, Atala A. Amnion Membrane Hydrogel and Amnion Membrane Powder Accelerate Wound Healing in a Full Thickness Porcine Skin Wound Model. Stem Cells Translational Medicine. PMID 31328435 DOI: 10.1002/Sctm.19-0101  0.306
2019 Forsythe S, Mehta N, Devarasetty M, Sivakumar H, Gmeiner W, Soker S, Votanopoulos K, Skardal A. Development of a Colorectal Cancer 3D Micro-tumor Construct Platform From Cell Lines and Patient Tumor Biospecimens for Standard-of-Care and Experimental Drug Screening. Annals of Biomedical Engineering. PMID 31020445 DOI: 10.1007/S10439-019-02269-2  0.402
2019 Albanna M, Binder KW, Murphy SV, Kim J, Qasem SA, Zhao W, Tan J, El-Amin IB, Dice DD, Marco J, Green J, Xu T, Skardal A, Holmes JH, Jackson JD, et al. In Situ Bioprinting of Autologous Skin Cells Accelerates Wound Healing of Extensive Excisional Full-Thickness Wounds. Scientific Reports. 9: 1856. PMID 30755653 DOI: 10.1038/S41598-018-38366-W  0.309
2019 Devarasetty M, Herberg S, Dominijanni A, Willey-Shelkey E, Skardal A, Soker S. Biofabricated tumor microenvironments for studying colorectal cancer in vitro and in vivo. Journal of Clinical Oncology. 37: e14689-e14689. DOI: 10.1200/Jco.2019.37.15_Suppl.E14689  0.404
2019 Mazzocchi A, Soker S, Skardal A. 3D bioprinting for high-throughput screening: Drug screening, disease modeling, and precision medicine applications Applied Physics Reviews. 6: 011302. DOI: 10.1063/1.5056188  0.437
2019 Rodriguez C, Aleman J, Almeida-Porada G, Porada C, Nikiforov M, Skardal A. High throughput 3D bioprinting of patient-derived multiple myeloma organoid models for niche recapitulation and chemosensitivity assessment. Clinical Lymphoma Myeloma and Leukemia. 19: e30-e31. DOI: 10.1016/J.Clml.2019.09.045  0.311
2019 Clark CC, Aleman J, Mutkus L, Skardal A. A mechanically robust thixotropic collagen and hyaluronic acid bioink supplemented with gelatin nanoparticles Bioprinting. 16: e00058. DOI: 10.1016/J.Bprint.2019.E00058  0.365
2018 Aleman J, Skardal A. A multi-site metastasis-on-a-chip microphysiological system for assessing metastatic preference of cancer cells. Biotechnology and Bioengineering. PMID 30450540 DOI: 10.1002/Bit.26871  0.381
2018 Mazzocchi A, Devarasetty M, Huntwork RC, Soker S, Skardal A. Optimization of collagen type I-hyaluronan hybrid bioink for 3D bioprinted liver microenvironments. Biofabrication. PMID 30270846 DOI: 10.1088/1758-5090/Aae543  0.457
2018 Mazzocchi AR, Rajan SAP, Votanopoulos KI, Hall AR, Skardal A. In vitro patient-derived 3D mesothelioma tumor organoids facilitate patient-centric therapeutic screening. Scientific Reports. 8: 2886. PMID 29440675 DOI: 10.1038/S41598-018-21200-8  0.334
2018 Serban MA, Skardal A. Hyaluronan chemistries for three-dimensional matrix applications. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29438729 DOI: 10.1016/J.Matbio.2018.02.010  0.654
2018 Devarasetty M, Mazzocchi AR, Skardal A. Applications of Bioengineered 3D Tissue and Tumor Organoids in Drug Development and Precision Medicine: Current and Future. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. PMID 29383499 DOI: 10.1007/S40259-017-0258-X  0.481
2018 Shi L, Foster B, Harris K, Skardal A, Kerr BA. Abstract B027: CD117 tyrosine kinase activation drives prostate cancer aggressiveness Cancer Research. 78. DOI: 10.1158/1538-7445.Prca2017-B027  0.308
2018 Skardal A. Perspective: “Universal” bioink technology for advancing extrusion bioprinting-based biomanufacturing Bioprinting. 10: e00026. DOI: 10.1016/J.Bprint.2018.E00026  0.334
2018 Mazzocchi A, Votanopoulos K, Skardal A. Personalizing Cancer Treatments Empirically in the Laboratory: Patient-Specific Tumor Organoids for Optimizing Precision Medicine Current Stem Cell Reports. 4: 97-104. DOI: 10.1007/S40778-018-0122-Z  0.391
2017 Sivakumar H, Strowd R, Skardal A. Exploration of Dynamic Elastic Modulus Changes on Glioblastoma Cell Populations with Aberrant EGFR Expression as a Potential Therapeutic Intervention Using a Tunable Hyaluronic Acid Hydrogel Platform. Gels (Basel, Switzerland). 3. PMID 30920523 DOI: 10.3390/Gels3030028  0.352
2017 Murphy SV, Skardal A, Song L, Sutton K, Haug R, Mack DL, Jackson J, Soker S, Atala A. Solubilized Amnion Membrane Hyaluronic Acid Hydrogel Accelerates Full-Thickness Wound Healing. Stem Cells Translational Medicine. PMID 28941321 DOI: 10.1002/Sctm.17-0053  0.336
2017 Yi H, Forsythe S, He Y, Liu Q, Geng X, Wei S, Li G, Atala A, Skardal A, Zhang Y. Tissue-Specific Extracellular Matrix Promotes Myogenic Differentiation of Human Muscle Progenitor Cells on Gelatin and Heparin Conjugated Alginate Hydrogels. Acta Biomaterialia. PMID 28823716 DOI: 10.1016/J.Actbio.2017.08.022  0.39
2017 Skardal A, Murphy SV, Devarasetty M, Mead I, Kang HW, Seol YJ, Shrike Zhang Y, Shin SR, Zhao L, Aleman J, Hall AR, Shupe TD, Kleensang A, Dokmeci MR, Jin Lee S, et al. Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform. Scientific Reports. 7: 8837. PMID 28821762 DOI: 10.1038/S41598-017-08879-X  0.376
2017 Devarasetty M, Forsythe S, Shupe TD, Soker S, Bishop CE, Atala A, Skardal A. Optical Tracking and Digital Quantification of Beating Behavior in Bioengineered Human Cardiac Organoids. Biosensors. 7. PMID 28644395 DOI: 10.3390/Bios7030024  0.309
2017 Devarasetty M, Wang E, Soker S, Skardal A. Mesenchymal stem cells support growth and organization of host-liver colorectal-tumor organoids and possibly resistance to chemotherapy. Biofabrication. 9: 021002. PMID 28589925 DOI: 10.1088/1758-5090/Aa7484  0.419
2017 Zhang YS, Aleman J, Shin SR, Kilic T, Kim D, Mousavi Shaegh SA, Massa S, Riahi R, Chae S, Hu N, Avci H, Zhang W, Silvestri A, Sanati Nezhad A, Manbohi A, ... ... Skardal A, et al. Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors. Proceedings of the National Academy of Sciences of the United States of America. PMID 28265064 DOI: 10.1073/Pnas.1612906114  0.361
2017 Harris K, Shi L, Peak T, Sanders S, Skardal A, Kerr B. Abstract 1983: CD117 expression and activation induce prostate cancer metastasis Cancer Research. 77: 1983-1983. DOI: 10.1158/1538-7445.Am2017-1983  0.314
2016 Skardal A, Shupe T, Atala A. Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling. Drug Discovery Today. PMID 27422270 DOI: 10.1016/J.Drudis.2016.07.003  0.377
2016 Skardal A, Murphy SV, Crowell K, Mack D, Atala A, Soker S. A tunable hydrogel system for long-term release of cell-secreted cytokines and bioprinted in situ wound cell delivery. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. PMID 27351939 DOI: 10.1002/Jbm.B.33736  0.386
2016 Skardal A, Devarasetty M, Kang HW, Seol YJ, Forsythe SD, Bishop C, Shupe T, Soker S, Atala A. Bioprinting Cellularized Constructs Using a Tissue-specific Hydrogel Bioink. Journal of Visualized Experiments : Jove. PMID 27166839 DOI: 10.3791/53606  0.455
2016 Skardal A, Devarasetty M, Forsythe S, Atala A, Soker S. A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening. Biotechnology and Bioengineering. PMID 26888480 DOI: 10.1002/Bit.25950  0.417
2015 Deegan DB, Zimmerman C, Skardal A, Atala A, Shupe TD. Stiffness of hyaluronic acid gels containing liver extracellular matrix supports human hepatocyte function and alters cell morphology. Journal of the Mechanical Behavior of Biomedical Materials. 55: 87-103. PMID 26569044 DOI: 10.1016/J.Jmbbm.2015.10.016  0.393
2015 Skardal A, Devarasetty M, Soker S, Hall AR. In situ patterned micro 3D liver constructs for parallel toxicology testing in a fluidic device. Biofabrication. 7: 031001. PMID 26355538 DOI: 10.1088/1758-5090/7/3/031001  0.436
2015 Skardal A, Devarasetty M, Kang HW, Mead I, Bishop C, Shupe T, Lee SJ, Jackson J, Yoo J, Soker S, Atala A. A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs. Acta Biomaterialia. PMID 26210285 DOI: 10.1016/J.Actbio.2015.07.030  0.458
2015 Skardal A, Devarasetty M, Rodman C, Atala A, Soker S. Liver-Tumor Hybrid Organoids for Modeling Tumor Growth and Drug Response In Vitro. Annals of Biomedical Engineering. 43: 2361-73. PMID 25777294 DOI: 10.1007/S10439-015-1298-3  0.427
2015 Skardal A, Atala A. Biomaterials for integration with 3-D bioprinting. Annals of Biomedical Engineering. 43: 730-46. PMID 25476164 DOI: 10.1007/S10439-014-1207-1  0.421
2015 Skardal A. Bioprinting essentials of cell and protein viability Essentials of 3d Biofabrication and Translation. 1-17. DOI: 10.1016/B978-0-12-800972-7.00001-3  0.337
2014 Niu G, Choi JS, Wang Z, Skardal A, Giegengack M, Soker S. Heparin-modified gelatin scaffolds for human corneal endothelial cell transplantation. Biomaterials. 35: 4005-14. PMID 24508079 DOI: 10.1016/J.Biomaterials.2014.01.033  0.394
2013 Markert CD, Guo X, Skardal A, Wang Z, Bharadwaj S, Zhang Y, Bonin K, Guthold M. Characterizing the micro-scale elastic modulus of hydrogels for use in regenerative medicine. Journal of the Mechanical Behavior of Biomedical Materials. 27: 115-27. PMID 23916408 DOI: 10.1016/J.Jmbbm.2013.07.008  0.349
2013 Park AH, Hoyt D, Britt D, Chase S, Tansavatdi K, Hunter L, McGill L, Sheng X, Skardal A, Prestwich GD. Cross-linked hydrogel and polyester resorbable ventilation tubes in a Chinchilla model. The Laryngoscope. 123: 1043-8. PMID 23512811 DOI: 10.1002/Lary.23712  0.436
2013 Skardal A, Mack D, Atala A, Soker S. Substrate elasticity controls cell proliferation, surface marker expression and motile phenotype in amniotic fluid-derived stem cells. Journal of the Mechanical Behavior of Biomedical Materials. 17: 307-16. PMID 23122714 DOI: 10.1016/J.Jmbbm.2012.10.001  0.376
2013 Murphy SV, Skardal A, Atala A. Evaluation of hydrogels for bio-printing applications. Journal of Biomedical Materials Research. Part A. 101: 272-84. PMID 22941807 DOI: 10.1002/Jbm.A.34326  0.379
2012 Skardal A, Mack D, Kapetanovic E, Atala A, Jackson JD, Yoo J, Soker S. Bioprinted amniotic fluid-derived stem cells accelerate healing of large skin wounds. Stem Cells Translational Medicine. 1: 792-802. PMID 23197691 DOI: 10.5966/Sctm.2012-0088  0.386
2012 Skardal A, Smith L, Bharadwaj S, Atala A, Soker S, Zhang Y. Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function. Biomaterials. 33: 4565-75. PMID 22475531 DOI: 10.1016/J.Biomaterials.2012.03.034  0.396
2011 Oottamasathien S, Jia W, McCoard L, Slack S, Zhang J, Skardal A, Job K, Kennedy TP, Dull RO, Prestwich GD. A murine model of inflammatory bladder disease: cathelicidin peptide induced bladder inflammation and treatment with sulfated polysaccharides. The Journal of Urology. 186: 1684-92. PMID 21855919 DOI: 10.1016/J.Juro.2011.03.099  0.454
2010 Skardal A, Zhang J, McCoard L, Oottamasathien S, Prestwich GD. Dynamically crosslinked gold nanoparticle - hyaluronan hydrogels. Advanced Materials (Deerfield Beach, Fla.). 22: 4736-40. PMID 20730818 DOI: 10.1002/Adma.201001436  0.395
2010 Skardal A, Sarker SF, Crabbé A, Nickerson CA, Prestwich GD. The generation of 3-D tissue models based on hyaluronan hydrogel-coated microcarriers within a rotating wall vessel bioreactor. Biomaterials. 31: 8426-35. PMID 20692703 DOI: 10.1016/J.Biomaterials.2010.07.047  0.585
2010 Skardal A, Zhang J, Prestwich GD. Bioprinting vessel-like constructs using hyaluronan hydrogels crosslinked with tetrahedral polyethylene glycol tetracrylates. Biomaterials. 31: 6173-81. PMID 20546891 DOI: 10.1016/J.Biomaterials.2010.04.045  0.561
2010 Skardal A, Zhang J, McCoard L, Xu X, Oottamasathien S, Prestwich GD. Photocrosslinkable hyaluronan-gelatin hydrogels for two-step bioprinting. Tissue Engineering. Part A. 16: 2675-85. PMID 20387987 DOI: 10.1089/Ten.Tea.2009.0798  0.571
2008 Zhang J, Skardal A, Prestwich GD. Engineered extracellular matrices with cleavable crosslinkers for cell expansion and easy cell recovery. Biomaterials. 29: 4521-31. PMID 18768219 DOI: 10.1016/J.Biomaterials.2008.08.008  0.54
2008 Liu Y, Skardal A, Shu XZ, Prestwich GD. Prevention of peritendinous adhesions using a hyaluronan-derived hydrogel film following partial-thickness flexor tendon injury. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 562-9. PMID 17985390 DOI: 10.1002/Jor.20499  0.424
Show low-probability matches.