William S. Denney, Ph.D. - Publications

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Chemical Engineering, Biomedical Engineering

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kurtz CB, Millet YA, Puurunen MK, Perreault M, Charbonneau MR, Isabella VM, Kotula JW, Antipov E, Dagon Y, Denney WS, Wagner DA, West KA, Degar AJ, Brennan AM, Miller PF. An engineered Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans. Science Translational Medicine. 11. PMID 30651324 DOI: 10.1126/Scitranslmed.Aau7975  0.306
2019 Arroyo S, Tiessen RG, Denney WS, Jin J, van Iersel MP(, Zeitz H, Manning AM, Schipperus MR, Bussel JB. Hyper-Sialylated IgG M254, an Innovative Therapeutic Candidate, Evaluated in Healthy Volunteers and in Patients with Immune Thrombocytopenia Purpura: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Blood. 134: 1090-1090. DOI: 10.1182/Blood-2019-125993  0.333
2015 Nayak S, Lee D, Arkin S, Martin SW, Heatherington AC, Denney WS, Vicini P, Hua F. A Quantitative Systems Pharmacology Model for the Coagulation Network Describes Biomarker Changes Observed in a Clinical Study with FXa Variant and Predicts Age-Associated Biomarker Variations Blood. 126: 3502-3502. DOI: 10.1182/Blood.V126.23.3502.3502  0.333
2014 Sharma R, Litchfield J, Atkinson K, Eng H, Amin NB, Denney WS, Pettersen JC, Goosen TC, Di L, Lee E, Pfefferkorn JA, Dalvie DK, Kalgutkar AS. Metabolites in safety testing assessment in early clinical development: a case study with a glucokinase activator. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 1926-39. PMID 25142735 DOI: 10.1124/Dmd.114.060087  0.315
2012 Reitman ML, Dishy V, Moreau A, Denney WS, Liu C, Kraft WK, Mejia AV, Matson MA, Stoch SA, Wagner JA, Lai E. Pharmacokinetics and pharmacodynamics of MK-5046, a bombesin receptor subtype-3 (BRS-3) agonist, in healthy patients. Journal of Clinical Pharmacology. 52: 1306-16. PMID 22162541 DOI: 10.1177/0091270011419854  0.315
2010 Chatterjee MS, Denney WS, Jing H, Diamond SL. Systems biology of coagulation initiation: kinetics of thrombin generation in resting and activated human blood. Plos Computational Biology. 6. PMID 20941387 DOI: 10.1371/Journal.Pcbi.1000950  0.728
2010 Sinclair SR, Kane SA, Van der Schueren BJ, Xiao A, Willson KJ, Boyle J, de Lepeleire I, Xu Y, Hickey L, Denney WS, Li CC, Palcza J, Vanmolkot FH, Depré M, Van Hecken A, et al. Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974). British Journal of Clinical Pharmacology. 69: 15-22. PMID 20078608 DOI: 10.1111/J.1365-2125.2009.03543.X  0.359
2008 Okorie UM, Denney WS, Chatterjee MS, Neeves KB, Diamond SL. Determination of surface tissue factor thresholds that trigger coagulation at venous and arterial shear rates: amplification of 100 fM circulating tissue factor requires flow. Blood. 111: 3507-13. PMID 18203955 DOI: 10.1182/Blood-2007-08-106229  0.619
2006 Gosalia DN, Denney WS, Salisbury CM, Ellman JA, Diamond SL. Functional phenotyping of human plasma using a 361-fluorogenic substrate biosensing microarray. Biotechnology and Bioengineering. 94: 1099-110. PMID 16575920 DOI: 10.1002/Bit.20927  0.702
2005 Lo K, Denney WS, Diamond SL. Stochastic modeling of blood coagulation initiation. Pathophysiology of Haemostasis and Thrombosis. 34: 80-90. PMID 16432310 DOI: 10.1159/000089929  0.681
2005 Edmondson KE, Denney WS, Diamond SL. Neutrophil-bead collision assay: pharmacologically induced changes in membrane mechanics regulate the PSGL-1/P-selectin adhesion lifetime. Biophysical Journal. 89: 3603-14. PMID 16100264 DOI: 10.1529/Biophysj.105.066134  0.629
2005 Denney WS, Lo K, Diamond SL. Stochastic modeling of extrinsic blood coagulation dynamics Aiche Annual Meeting, Conference Proceedings. 8744.  0.539
2005 Gosalia DN, Denney WS, Salisbury C, Ellman J, Diamond SL. Enzyme assay microarrays for biomarker detection Aiche Annual Meeting, Conference Proceedings. 8959.  0.713
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