Dimitrios Morikis - Publications

Bioengineering University of California, Riverside, Riverside, CA, United States 
General Biophysics, Pharmacy

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Narkhede YB, Gautam AK, Hsu RV, Rodriguez W, Zewde NT, Harrison RES, Arantes PR, Gaieb Z, Gorham RD, Kieslich C, Morikis D, Sahu A, Palermo G. Role of Electrostatic Hotspots in the Selectivity of Complement Control Proteins Toward Human and Bovine Complement Inhibition. Frontiers in Molecular Biosciences. 8: 618068. PMID 33829039 DOI: 10.3389/fmolb.2021.618068  1
2018 Mohan RR, Wilson M, Gorham RD, Harrison RES, Morikis VA, Kieslich CA, Orr AA, Coley AV, Tamamis P, Morikis D. Virtual Screening of Chemical Compounds for Discovery of Complement C3 Ligands. Acs Omega. 3: 6427-6438. PMID 30221234 DOI: 10.1021/acsomega.8b00606  1
2018 Malik-Chaudhry HK, Gaieb Z, Saavedra A, Reyes M, Kung R, Le F, Morikis D, Liao J. Dissecting Distinct Roles of NEDDylation E1 Ligase Heterodimer APPBP1 and UBA3 Reveals Potential Evolution Process for Activation of Ubiquitin-related Pathways. Scientific Reports. 8: 10108. PMID 29973603 DOI: 10.1038/S41598-018-28214-2  0.68
2018 Zewde N, Morikis D. A computational model for the evaluation of complement system regulation under homeostasis, disease, and drug intervention. Plos One. 13: e0198644. PMID 29874282 DOI: 10.1371/Journal.Pone.0198644  0.68
2017 Harrison RES, Mohan RR, Gorham RD, Kieslich CA, Morikis D. AESOP: A Python Library for Investigating Electrostatics in Protein Interactions. Biophysical Journal. 112: 1761-1766. PMID 28494947 DOI: 10.1016/J.Bpj.2017.04.005  1
2017 Gaieb Z, Morikis D. Conformational heterogeneity in CCR7 undergoes transitions to specific states upon ligand binding. Journal of Molecular Graphics & Modelling. 74: 352-358. PMID 28477575 DOI: 10.1016/J.Jmgm.2017.04.012  0.68
2017 Gaieb Z, Morikis D. Detection of Side Chain Rearrangements Mediating the Motions of Transmembrane Helices in Molecular Dynamics Simulations of G Protein-Coupled Receptors. Computational and Structural Biotechnology Journal. 15: 131-137. PMID 28149485 DOI: 10.1016/J.Csbj.2017.01.001  0.68
2016 Mohan RR, Cabrera AP, Harrison RE, Gorham RD, Johnson LV, Ghosh K, Morikis D. Peptide redesign for inhibition of the complement system: Targeting age-related macular degeneration. Molecular Vision. 22: 1280-1290. PMID 27829783  1
2016 Gaieb Z, Lo DD, Morikis D. Molecular Mechanism of Biased Ligand Conformational Changes in CC Chemokine Receptor 7. Journal of Chemical Information and Modeling. PMID 27529431 DOI: 10.1021/Acs.Jcim.6B00367  0.68
2016 Croker DE, Monk PN, Halai R, Kaeslin G, Schofield Z, Wu MC, Clark RJ, Blaskovich MA, Morikis D, Floudas CA, Cooper MA, Woodruff TM. Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signaling. Immunology and Cell Biology. PMID 27108698 DOI: 10.1038/Icb.2016.43  1
2016 Mohan RR, Huber GA, Morikis D. Electrostatic Steering Accelerates C3d:CR2 Association. The Journal of Physical Chemistry. B. PMID 27092816 DOI: 10.1021/Acs.Jpcb.6B02095  1
2016 Zewde N, Gorham RD, Dorado A, Morikis D. Quantitative Modeling of the Alternative Pathway of the Complement System. Plos One. 11: e0152337. PMID 27031863 DOI: 10.1371/Journal.Pone.0152337  1
2016 Gaieb Z, Lo DD, Morikis D. Ligand-Specific Conformational Changes in CCR7 Coupled to Selecting Different Signaling Pathways upon CCL19 And CCL21 Ligand Binding Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.1947  0.68
2015 Gorham RD, Nunez V, Lin JH, Rooijakkers SH, Vullev VI, Morikis D. Discovery of small molecules for fluorescent detection of complement activation product C3d. Journal of Medicinal Chemistry. PMID 26613117 DOI: 10.1021/Acs.Jmedchem.5B01062  1
2015 Zhang C, Brown MQ, van de Ven W, Zhang ZM, Wu B, Young MC, Synek L, Borchardt D, Harrison R, Pan S, Luo N, Huang YM, Ghang YJ, Ung N, Li R, ... ... Morikis D, et al. Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26607451 DOI: 10.1073/Pnas.1521248112  1
2015 Chen CZ, Gorham RD, Gaieb Z, Morikis D. Electrostatic Interactions between Complement Regulator CD46(SCR1-2) and Adenovirus Ad11/Ad21 Fiber Protein Knob. Molecular Biology International. 2015: 967465. PMID 26357573 DOI: 10.1155/2015/967465  1
2015 Bennett KM, Gorham RD, Gusti V, Trinh L, Morikis D, Lo DD. Hybrid flagellin as a T cell independent vaccine scaffold. Bmc Biotechnology. 15: 71. PMID 26265529 DOI: 10.1186/s12896-015-0194-0  1
2015 E S Harrison R, Gorham RD, Morikis D. Energetic evaluation of binding modes in the C3d and Factor H (CCP 19-20) complex. Protein Science : a Publication of the Protein Society. 24: 789-802. PMID 25628052 DOI: 10.1002/Pro.2650  1
2015 Gorham RD, Forest DL, Khoury GA, Smadbeck J, Beecher CN, Healy ED, Tamamis P, Archontis G, Larive CK, Floudas CA, Radeke MJ, Johnson LV, Morikis D. New compstatin peptides containing N-terminal extensions and non-natural amino acids exhibit potent complement inhibition and improved solubility characteristics. Journal of Medicinal Chemistry. 58: 814-26. PMID 25494040 DOI: 10.1021/Jm501345Y  1
2015 Mohan RR, Gorham RD, Morikis D. A theoretical view of the C3d:CR2 binding controversy. Molecular Immunology. 64: 112-22. PMID 25433434 DOI: 10.1016/J.Molimm.2014.11.006  1
2015 Bennett KM, Gorham RD, Gusti V, Trinh L, Morikis D, Lo DD. Hybrid flagellin as a T cell independent vaccine scaffold Bmc Biotechnology. 15. DOI: 10.1186/s12896-015-0194-0  1
2014 Halai R, Bellows-Peterson ML, Branchett W, Smadbeck J, Kieslich CA, Croker DE, Cooper MA, Morikis D, Woodruff TM, Floudas CA, Monk PN. Derivation of ligands for the complement C3a receptor from the C-terminus of C5a. European Journal of Pharmacology. 745: 176-81. PMID 25446428 DOI: 10.1016/J.Ejphar.2014.10.041  1
2014 Tamamis P, Kieslich CA, Nikiforovich GV, Woodruff TM, Morikis D, Archontis G. Insights into the mechanism of C5aR inhibition by PMX53 via implicit solvent molecular dynamics simulations and docking. Bmc Biophysics. 7: 5. PMID 25170421 DOI: 10.1186/2046-1682-7-5  1
2014 Ojha H, Panwar HS, Gorham RD, Morikis D, Sahu A. Viral regulators of complement activation: structure, function and evolution. Molecular Immunology. 61: 89-99. PMID 24976595 DOI: 10.1016/J.Molimm.2014.06.004  1
2014 Liu Y, Kieslich CA, Morikis D, Liao J. Engineering pre-SUMO4 as efficient substrate of SENP2. Protein Engineering, Design & Selection : Peds. 27: 117-26. PMID 24671712 DOI: 10.1093/Protein/Gzu004  1
2014 Gorham RD, Rodriguez W, Morikis D. Molecular analysis of the interaction between staphylococcal virulence factor Sbi-IV and complement C3d. Biophysical Journal. 106: 1164-73. PMID 24606940 DOI: 10.1016/J.Bpj.2014.01.033  1
2013 Gorham RD, Forest DL, Tamamis P, López de Victoria A, Kraszni M, Kieslich CA, Banna CD, Bellows-Peterson ML, Larive CK, Floudas CA, Archontis G, Johnson LV, Morikis D. Novel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures. Experimental Eye Research. 116: 96-108. PMID 23954241 DOI: 10.1016/J.Exer.2013.07.023  1
2013 Kieslich CA, Shin D, López de Victoria A, González-Rivera G, Morikis D. A predictive model for HIV type 1 coreceptor selectivity. Aids Research and Human Retroviruses. 29: 1386-94. PMID 23808984 DOI: 10.1089/Aid.2012.0173  1
2012 Kieslich CA, Morikis D. The two sides of complement C3d: evolution of electrostatics in a link between innate and adaptive immunity. Plos Computational Biology. 8: e1002840. PMID 23300422 DOI: 10.1371/Journal.Pcbi.1002840  1
2012 López de Victoria A, Tamamis P, Kieslich CA, Morikis D. Insights into the structure, correlated motions, and electrostatic properties of two HIV-1 gp120 V3 loops. Plos One. 7: e49925. PMID 23185486 DOI: 10.1371/Journal.Pone.0049925  1
2012 Bellows-Peterson ML, Fung HK, Floudas CA, Kieslich CA, Zhang L, Morikis D, Wareham KJ, Monk PN, Hawksworth OA, Woodruff TM. De novo peptide design with C3a receptor agonist and antagonist activities: theoretical predictions and experimental validation. Journal of Medicinal Chemistry. 55: 4159-68. PMID 22500977 DOI: 10.1021/Jm201609K  1
2012 López de Victoria A, Kieslich CA, Rizos AK, Krambovitis E, Morikis D. Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties. Bmc Biophysics. 5: 3. PMID 22313935 DOI: 10.1186/2046-1682-5-3  1
2012 Tamamis P, López de Victoria A, Gorham RD, Bellows-Peterson ML, Pierou P, Floudas CA, Morikis D, Archontis G. Molecular dynamics in drug design: new generations of compstatin analogs. Chemical Biology & Drug Design. 79: 703-18. PMID 22233517 DOI: 10.1111/J.1747-0285.2012.01324.X  1
2012 Gorham RD, Kieslich CA, Morikis D. CompleMent Inhibition by Staphylococcus aureus: Electrostatics of C3d-EfbC and C3d-Ehp association Cellular and Molecular Bioengineering. 5: 32-43. DOI: 10.1007/S12195-011-0195-6  1
2011 Hakkoymaz H, Kieslich CA, Jr RD, Gunopulos D, Morikis D. Electrostatic Similarity Determination Using Multiresolution Analysis. Molecular Informatics. 30: 733-46. PMID 27467264 DOI: 10.1002/Minf.201100002  1
2011 Tamamis P, Pierou P, Mytidou C, Floudas CA, Morikis D, Archontis G. Design of a modified mouse protein with ligand binding properties of its human analog by molecular dynamics simulations: the case of C3 inhibition by compstatin. Proteins. 79: 3166-79. PMID 21989937 DOI: 10.1002/Prot.23149  1
2011 El-Assaad AM, Kieslich CA, Gorham RD, Morikis D. Electrostatic exploration of the C3d-FH4 interaction using a computational alanine scan. Molecular Immunology. 48: 1844-50. PMID 21683447 DOI: 10.1016/J.Molimm.2011.05.007  1
2011 Kieslich CA, Vazquez H, Goodman GN, López de Victoria A, Morikis D. The effect of electrostatics on factor H function and related pathologies. Journal of Molecular Graphics & Modelling. 29: 1047-55. PMID 21605993 DOI: 10.1016/J.Jmgm.2011.04.010  1
2011 Gorham RD, Kieslich CA, Nichols A, Sausman NU, Foronda M, Morikis D. An evaluation of Poisson-Boltzmann electrostatic free energy calculations through comparison with experimental mutagenesis data. Biopolymers. 95: 746-54. PMID 21538330 DOI: 10.1002/Bip.21644  1
2011 Kieslich CA, Morikis D, Yang J, Gunopulos D. Automated computational framework for the analysis of electrostatic similarities of proteins. Biotechnology Progress. 27: 316-25. PMID 21485028 DOI: 10.1002/Btpr.541  1
2011 López de Victoria A, Gorham RD, Bellows-Peterson ML, Ling J, Lo DD, Floudas CA, Morikis D. A new generation of potent complement inhibitors of the Compstatin family. Chemical Biology & Drug Design. 77: 431-40. PMID 21352502 DOI: 10.1111/J.1747-0285.2011.01111.X  1
2011 Gorham RD, Kieslich CA, Morikis D. Electrostatic clustering and free energy calculations provide a foundation for protein design and optimization. Annals of Biomedical Engineering. 39: 1252-63. PMID 21140293 DOI: 10.1007/S10439-010-0226-9  1
2011 Qureshi NN, Morikis D, Schiller NL. Contribution of specific amino acid changes in penicillin binding protein 1 to amoxicillin resistance in clinical Helicobacter pylori isolates. Antimicrobial Agents and Chemotherapy. 55: 101-9. PMID 20956585 DOI: 10.1128/Aac.00545-10  1
2011 Kieslich CA, Gorham RD, Morikis D. Is the rigid-body assumption reasonable?: Insights into the effects of dynamics on the electrostatic analysis of barnase-barstar Journal of Non-Crystalline Solids. 357: 707-716. DOI: 10.1016/J.Jnoncrysol.2010.05.087  1
2011 Hakkoymaz H, Kieslich CA, Gorham RD, Gunopulos D, Morikis D. Electrostatic similarity determination using multiresolution analysis Molecular Informatics. 30: 733-746. DOI: 10.1002/minf.201100002  1
2010 Chae K, Gonong BJ, Kim SC, Kieslich CA, Morikis D, Balasubramanian S, Lord EM. A multifaceted study of stigma/style cysteine-rich adhesin (SCA)-like Arabidopsis lipid transfer proteins (LTPs) suggests diversified roles for these LTPs in plant growth and reproduction. Journal of Experimental Botany. 61: 4277-90. PMID 20667964 DOI: 10.1093/Jxb/Erq228  1
2010 Tamamis P, Morikis D, Floudas CA, Archontis G. Species specificity of the complement inhibitor compstatin investigated by all-atom molecular dynamics simulations. Proteins. 78: 2655-67. PMID 20589629 DOI: 10.1002/Prot.22780  1
2010 Bellows ML, Fung HK, Taylor MS, Floudas CA, López de Victoria A, Morikis D. New compstatin variants through two de novo protein design frameworks. Biophysical Journal. 98: 2337-46. PMID 20483343 DOI: 10.1016/J.Bpj.2010.01.057  1
2010 Zhao H, Hakala M, Lappalainen P. ADF/cofilin binds phosphoinositides in a multivalent manner to act as a PIP(2)-density sensor. Biophysical Journal. 98: 2327-36. PMID 20483342 DOI: 10.1016/j.bpj.2010.01.046  1
2010 Cheung AS, Kieslich CA, Yang J, Morikis D. Solvation effects in calculated electrostatic association free energies for the C3d-CR2 complex and comparison with experimental data. Biopolymers. 93: 509-19. PMID 20091675 DOI: 10.1002/Bip.21388  1
2010 Pyaram K, Kieslich CA, Yadav VN, Morikis D, Sahu A. Influence of electrostatics on the complement regulatory functions of Kaposica, the complement inhibitor of Kaposi's sarcoma-associated herpesvirus. Journal of Immunology (Baltimore, Md. : 1950). 184: 1956-67. PMID 20089702 DOI: 10.4049/Jimmunol.0903261  1
2009 Chae K, Kieslich CA, Morikis D, Kim SC, Lord EM. A gain-of-function mutation of Arabidopsis lipid transfer protein 5 disturbs pollen tube tip growth and fertilization. The Plant Cell. 21: 3902-14. PMID 20044438 DOI: 10.1105/Tpc.109.070854  1
2009 Galanakis PA, Kandias NG, Rizos AK, Morikis D, Krambovitis E, Spyroulias GA. NMR evidence of charge-dependent interaction between various PND V3 and CCR5 N-terminal peptides. Biopolymers. 92: 94-109. PMID 19117029 DOI: 10.1002/Bip.21127  1
2008 Zhang L, Mallik B, Morikis D. Structural study of Ac-Phe-[Orn-Pro-dCha-Trp-Arg], a potent C5a receptor antagonist, by NMR. Biopolymers. 90: 803-15. PMID 18846566 DOI: 10.1002/Bip.21099  1
2008 Mallik B, Zhang L, Koide S, Morikis D. pH dependence of stability of the 10th human fibronectin type III domain: a computational study. Biotechnology Progress. 24: 48-55. PMID 17935345 DOI: 10.1021/Bp0700915  1
2008 Huynh N, Mallik B, Zhang L, Martins-Green M, Morikis D. Computational studies of CXCR1, the receptor of IL-8/CXCL8, using molecular dynamics and electrostatics. Biopolymers. 89: 52-61. PMID 17876799 DOI: 10.1002/Bip.20851  1
2008 Fung HK, Floudas CA, Taylor MS, Zhang L, Morikis D. Toward full-sequence de novo protein design with flexible templates for human beta-defensin-2. Biophysical Journal. 94: 584-99. PMID 17827237 DOI: 10.1529/Biophysj.107.110627  1
2008 Pyaram K, Kieslich C, Yadav VN, Morikis D, Sahu A. Influence of electrostatic potential on the complement regulatory functions of Kaposica, the complement inhibitor of Kaposi's sarcoma-associated herpesvirus Molecular Immunology. 45: 4167-4168. DOI: 10.1016/J.Molimm.2008.08.217  0.36
2007 Zhang L, Morikis D. Solution structure of a bent alpha-helix. Biochemistry. 46: 12959-67. PMID 17941649 DOI: 10.1021/Bi701252N  1
2007 Chae K, Zhang K, Zhang L, Morikis D, Kim ST, Mollet JC, de la Rosa N, Tan K, Lord EM. Two SCA (stigma/style cysteine-rich adhesin) isoforms show structural differences that correlate with their levels of in vitro pollen tube adhesion activity. The Journal of Biological Chemistry. 282: 33845-58. PMID 17878166 DOI: 10.1074/Jbc.M703997200  1
2007 Tamamis P, Skourtis SS, Morikis D, Lambris JD, Archontis G. Conformational analysis of compstatin analogues with molecular dynamics simulations in explicit water. Journal of Molecular Graphics & Modelling. 26: 571-80. PMID 17498990 DOI: 10.1016/J.Jmgm.2007.03.014  1
2007 Zhang L, Mallik B, Morikis D. Immunophysical exploration of C3d-CR2(CCP1-2) interaction using molecular dynamics and electrostatics. Journal of Molecular Biology. 369: 567-83. PMID 17434528 DOI: 10.1016/J.Jmb.2007.02.101  1
2007 Morikis D, Rizos AK, Spandidos DA, Krambovitis E. Electrostatic modeling of peptides derived from the V3-loop of HIV-1 gp120: implications of the interaction with chemokine receptor CCR5. International Journal of Molecular Medicine. 19: 343-51. PMID 17273779 DOI: 10.3892/Ijmm.19.3.343  1
2006 Zhang L, Morikis D. Immunophysical properties and prediction of activities for vaccinia virus complement control protein and smallpox inhibitor of complement enzymes using molecular dynamics and electrostatics. Biophysical Journal. 90: 3106-19. PMID 16473914 DOI: 10.1529/Biophysj.105.068130  1
2006 Mallik B, Morikis D. Applications of molecular dynamics simulations in immunology: A useful computational method in aiding vaccine design Current Proteomics. 3: 259-270. DOI: 10.2174/157016406780655568  1
2006 Rizos AK, Tsikalas I, Morikis D, Galanakis P, Spyroulias GA, Krambovitis E. Characterization of the interaction between peptides derived from the gp120/V3 domain of HIV-1 and the amino terminal of the chemokine receptor CCR5 by NMR spectroscopy and light scattering Journal of Non-Crystalline Solids. 352: 4451-4458. DOI: 10.1016/J.Jnoncrysol.2006.01.137  1
2006 Morikis D, Zhang L. An immunophysical study of the complement system: Examples for the pH dependence of protein binding and stability Journal of Non-Crystalline Solids. 352: 4445-4450. DOI: 10.1016/J.Jnoncrysol.2006.01.104  1
2006 Wu J, Morikis D. Molecular thermodynamics for charged biomacromolecules Fluid Phase Equilibria. 241: 317-333. DOI: 10.1016/J.Fluid.2005.12.044  1
2005 Sfyroera G, Katragadda M, Morikis D, Isaacs SN, Lambris JD. Electrostatic modeling predicts the activities of orthopoxvirus complement control proteins. Journal of Immunology (Baltimore, Md. : 1950). 174: 2143-51. PMID 15699145 DOI: 10.4049/Jimmunol.174.4.2143  1
2005 Mallik B, Katragadda M, Spruce LA, Carafides C, Tsokos CG, Morikis D, Lambris JD. Design and NMR characterization of active analogues of compstatin containing non-natural amino acids. Journal of Medicinal Chemistry. 48: 274-86. PMID 15634022 DOI: 10.1021/Jm0495531  1
2005 Morikis D, Floudas CA, Lambris JD. Structure-based integrative computational and experimental approach for the optimization of drug design Lecture Notes in Computer Science. 3515: 680-688.  1
2004 Holland MC, Morikis D, Lambris JD. Synthetic small-molecule complement inhibitors. Current Opinion in Investigational Drugs (London, England : 2000). 5: 1164-73. PMID 15573867  1
2004 Morikis D, Lambris JD. Physical methods for structure, dynamics and binding in immunological research. Trends in Immunology. 25: 700-7. PMID 15530842 DOI: 10.1016/J.It.2004.09.009  1
2004 Katragadda M, Morikis D, Lambris JD. Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin. The Journal of Biological Chemistry. 279: 54987-95. PMID 15489226 DOI: 10.1074/Jbc.M409963200  1
2004 Morikis D, Lambris JD. The electrostatic nature of C3d-complement receptor 2 association. Journal of Immunology (Baltimore, Md. : 1950). 172: 7537-47. PMID 15187133 DOI: 10.4049/Jimmunol.172.12.7537  1
2004 Mastellos D, Morikis D, Strey C, Holland MC, Lambris JD. From atoms to systems: A cross-disciplinary approach to complement-mediated functions Molecular Immunology. 41: 153-164. PMID 15159061 DOI: 10.1016/J.Molimm.2004.03.016  1
2004 Morikis D, Soulika AM, Mallik B, Klepeis JL, Floudas CA, Lambris JD. Improvement of the anti-C3 activity of compstatin using rational and combinatorial approaches. Biochemical Society Transactions. 32: 28-32. PMID 14748706 DOI: 10.1042/Bst0320028  1
2004 Kim JH, Stephens JP, Morikis D, Ozkan M. Hybrid inorganic-organic molecular beacons Sensor Letters. 2: 85-90. DOI: 10.1166/s1.2004.042  1
2004 Kim JH, Morikis D, Ozkan M. Adaptation of inorganic quantum dots for stable molecular beacons Sensors and Actuators, B: Chemical. 102: 315-319. DOI: 10.1016/J.Snb.2004.04.107  1
2004 Klepeis JL, Floudas CA, Morikis D, Tsokos CG, Lambris JD. Design of peptide analogues with improved activity using a novel de novo protein design approach Industrial and Engineering Chemistry Research. 43: 3817-3826.  1
2003 Morikis D, Elcock AH, Jennings PA, McCammon JA. The pH dependence of stability of the activation helix and the catalytic site of GART. Biophysical Chemistry. 105: 279-91. PMID 14499900 DOI: 10.1016/S0301-4622(03)00079-6  1
2003 Mallik B, Lambris JD, Morikis D. Conformational interconversion in compstatin probed with molecular dynamics simulations. Proteins. 53: 130-41. PMID 12945056 DOI: 10.1002/Prot.10491  1
2003 Soulika AM, Morikis D, Sarrias MR, Roy M, Spruce LA, Sahu A, Lambris JD. Studies of structure-activity relations of complement inhibitor compstatin. Journal of Immunology (Baltimore, Md. : 1950). 171: 1881-90. PMID 12902490 DOI: 10.4049/Jimmunol.171.4.1881  1
2003 Banky P, Roy M, Newlon MG, Morikis D, Haste NM, Taylor SS, Jennings PA. Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform. Journal of Molecular Biology. 330: 1117-29. PMID 12860132 DOI: 10.1016/S0022-2836(03)00552-7  1
2003 Mastellos D, Morikis D, Isaacs SN, Holland MC, Strey CW, Lambris JD. Complement: structure, functions, evolution, and viral molecular mimicry. Immunologic Research. 27: 367-86. PMID 12857982 DOI: 10.1385/Ir:27:2-3:367  1
2003 Klepeis JL, Floudas CA, Morikis D, Tsokos CG, Argyropoulos E, Spruce L, Lambris JD. Integrated computational and experimental approach for lead optimization and design of compstatin variants with improved activity. Journal of the American Chemical Society. 125: 8422-3. PMID 12848533 DOI: 10.1021/Ja034846P  1
2003 Sahu A, Morikis D, Lambris JD. Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3. Molecular Immunology. 39: 557-66. PMID 12431389 DOI: 10.1016/S0161-5890(02)00212-2  1
2002 Morikis D, Lambris JD. Structural aspects and design of low-molecular-mass complement inhibitors Biochemical Society Transactions. 30: 1026-1036. PMID 12440966 DOI: 10.1042/Bst0301026  1
2002 Morikis D, Roy M, Newlon MG, Scott JD, Jennings PA. Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIalpha. European Journal of Biochemistry / Febs. 269: 2040-51. PMID 11985580 DOI: 10.1046/J.1432-1033.2002.02852.X  1
2002 Morikis D, Roy M, Sahu A, Troganis A, Jennings PA, Tsokos GC, Lambris JD. The structural basis of compstatin activity examined by structure-function-based design of peptide analogs and NMR. The Journal of Biological Chemistry. 277: 14942-53. PMID 11847226 DOI: 10.1074/Jbc.M200021200  1
2001 Morikis D, Elcock AH, Jennings PA, McCammon JA. Proton transfer dynamics of GART: the pH-dependent catalytic mechanism examined by electrostatic calculations. Protein Science : a Publication of the Protein Society. 10: 2379-92. PMID 11604543 DOI: 10.1110/Ps.17301  1
2001 Morikis D, Elcock AH, Jennings PA, McCammon JA. Native-state conformational dynamics of GART: a regulatory pH-dependent coil-helix transition examined by electrostatic calculations. Protein Science : a Publication of the Protein Society. 10: 2363-78. PMID 11604542 DOI: 10.1110/Ps.17201  1
2001 Newlon MG, Roy M, Morikis D, Carr DW, Westphal R, Scott JD, Jennings PA. A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes. The Embo Journal. 20: 1651-62. PMID 11285229 DOI: 10.1093/Emboj/20.7.1651  1
2000 Sahu A, Soulika AM, Morikis D, Spruce L, Moore WT, Lambris JD. Binding kinetics, structure-activity relationship, and biotransformation of the complement inhibitor Compstatin Journal of Immunology. 165: 2491-2499. PMID 10946275 DOI: 10.4049/Jimmunol.165.5.2491  1
2000 Sahu A, Soulika A, Morikis D, Spruce L, Moore WT, Lambris JD. Kinetics and proposed mechanism of binding of the complement inhibitor compstatin Immunopharmacology. 49: 53. DOI: 10.1016/S0162-3109(00)80155-1  0.36
1999 Newlon MG, Roy M, Morikis D, Hausken ZE, Coghlan V, Scott JD, Jennings PA. The molecular basis for protein kinase A anchoring revealed by solution NMR. Nature Structural Biology. 6: 222-7. PMID 10074940 DOI: 10.1038/6663  1
1999 Klepeis JL, Floudas CA, Morikis D, Lambris JD. Predicting peptide structures using NMR data and deterministic global optimization Journal of Computational Chemistry. 20: 1354-1370.  1
1998 Morikis D, Assa-Munt N, Sahu A, Lambris JD. Solution structure of Compstatin, a potent complement inhibitor Protein Science. 7: 619-627. PMID 9541394 DOI: 10.1002/Pro.5560070311  1
1996 Morikis D, Wright PE. Hydrogen exchange in the carbon monoxide complex of soybean leghemoglobin European Journal of Biochemistry. 237: 212-220. PMID 8620875 DOI: 10.1111/J.1432-1033.1996.0212N.X  1
1995 Brüschweiler R, Morikis D, Wright PE. Hydration of the partially folded peptide RN-24 studied by multidimensional NMR Journal of Biomolecular Nmr. 5: 353-356. PMID 7647554 DOI: 10.1007/Bf00182277  1
1994 Morikis D, Lepre CA, Wright PE. 1H resonance assignments and secondary structure of the carbon monoxide complex of soybean leghemoglobin determined by homonuclear two-dimensional and three-dimensional NMR spectroscopy European Journal of Biochemistry. 219: 611-626. PMID 8307026 DOI: 10.1111/J.1432-1033.1994.Tb19977.X  1
1993 Morikis D, Brüschweiler R, Wright PE. Determination of local ligand conformations in slowly tumbling proteins by homonuclear 2D and 3D NMR: Application to heme propionates in leghemoglobin Journal of the American Chemical Society. 115: 6238-6246.  1
1992 Sage JT, Morikis D, Li P, Champion PM. Low pH myoglobin photoproducts Biophysical Journal. 61: 1041-1044. PMID 1581497 DOI: 10.1016/S0006-3495(92)81912-4  1
1992 Zhu L, Sage JT, Rigos AA, Morikis D, Champion PM. Conformational interconversion in protein crystals Journal of Molecular Biology. 224: 207-215. PMID 1548699 DOI: 10.1016/0022-2836(92)90584-7  1
1991 Sage JT, Morikis D, Champion PM. Spectroscopic studies of myoglobin at low pH: Heme structure and ligation Biochemistry. 30: 1227-1237. PMID 1991102 DOI: 10.1021/Bi00219A010  1
1991 Morikis D, Li P, Bangcharoenpaurpong O, Sage JT, Champion PM. Resonance Raman scattering as a probe of electron-nuclear coupling: Applications to heme proteins Journal of Physical Chemistry. 95: 3391-3398. DOI: 10.1021/J100161A077  1
1991 Wells AV, Timothy Sage J, Morikis D, Champion PM, Chiu ML, Sligar SG. The iron-histidine mode of myoglobin revisited: resonance raman studies of isotopically labeled Escherichia coli expressed myoglobin Journal of the American Chemical Society. 113: 9655-9660.  1
1990 Morikis D, Champion PM, Springer BA, Egeberg KD, Sligar SG. Resonance Raman studies of iron spin and axial coordination in distal pocket mutants of ferric myoglobin Journal of Biological Chemistry. 265: 12143-12145. PMID 2373683  1
1990 Egeberg KD, Springer BA, Martinis SA, Sligar SG, Morikis D, Champion PM. Alteration of sperm whale myoglobin heme axial ligation by site-directed mutagenesis Biochemistry. 29: 9783-9791. PMID 2176857 DOI: 10.1021/Bi00494A004  1
1989 Morikis D, Champion PM, Springer BA, Sligar SG. Resonance Raman investigations of site-directed mutants of myoglobin: Effects of distal histidine replacement Biochemistry. 28: 4791-4800. PMID 2765511 DOI: 10.1021/Bi00437A041  1
1989 Sage JT, Morikis D, Champion PM. Resonance Raman studies of oriented chromophores: Metmyoglobin single crystals The Journal of Chemical Physics. 90: 3015-3032. DOI: 10.1063/1.455904  1
1988 Morikis D, Sage JT, Rizos AK, Champion PM. Resonance Raman studies of myoglobin single crystals Journal of the American Chemical Society. 110: 6341-6342. DOI: 10.1021/Ja00227A011  1
1987 Sligar SG, Egeberg KD, Sage JT, Morikis D, Champion PM. Alteration of heme axial ligands by site-directed mutagenesis: A cytochrome becomes a catalytic demethylase Journal of the American Chemical Society. 109: 7896-7897.  1
Show low-probability matches.