Meenhard Herlyn - Related publications

Affiliations: 
Bioengineering University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biomedical Engineering, Oncology, Cell Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Praktiknjo SD, Obermayer B, Zhu Q, Fang L, Liu H, Quinn H, Stoeckius M, Kocks C, Birchmeier W, Rajewsky N. Tracing tumorigenesis in a solid tumor model at single-cell resolution. Nature Communications. 11: 991. PMID 32080185 DOI: 10.1038/s41467-020-14777-0   
2020 Zhao J, Guo C, Xiong F, Yu J, Ge J, Wang H, Liao Q, Zhou Y, Gong Q, Xiang B, Zhou M, Li X, Li G, Xiong W, Fang J, et al. Single cell RNA-seq reveals the landscape of tumor and infiltrating immune cells in nasopharyngeal cancer. Cancer Letters. PMID 32061950 DOI: 10.1016/j.canlet.2020.02.010   
2020 Yoon J, Parish CR, Coupland LA. A Rapid and Accurate Bioluminescence-Based Migration Assay Permitting Analysis of Tumor Cell/Stromal Cell Interactions. Methods and Protocols. 3. PMID 31979362 DOI: 10.3390/mps3010010   
2020 Kim BJ, Hannanta-Anan P, Ryd A, Swartz MA, Wu M. Lymphoidal chemokine CCL19 promoted the heterogeneity of the breast tumor cell motility within a 3D microenvironment revealed by a Lévy distribution analysis. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 32055833 DOI: 10.1093/intbio/zyaa001   
2020 Lucchetti D, Ricciardi Tenore C, Colella F, Sgambato A. Extracellular Vesicles and Cancer: A Focus on Metabolism, Cytokines, and Immunity. Cancers. 12. PMID 32015297 DOI: 10.3390/cancers12010171   
2020 Bykov Y, Kim SH, Zamarin D. Preparation of single cells from tumors for single-cell RNA sequencing. Methods in Enzymology. 632: 295-308. PMID 32000902 DOI: 10.1016/bs.mie.2019.05.057   
2020 Liu G, Rui W, Zheng H, Huang D, Yu F, Zhang Y, Dong J, Zhao X, Lin X. CXCR2-modified CAR-T cells have enhanced trafficking ability that improves treatment of hepatocellular carcinoma. European Journal of Immunology. PMID 31981231 DOI: 10.1002/eji.201948457   
2020 Reuben A, Zhang J, Chiou SH, Gittelman RM, Li J, Lee WC, Fujimoto J, Behrens C, Liu X, Wang F, Quek K, Wang C, Kheradmand F, Chen R, Chow CW, et al. Comprehensive T cell repertoire characterization of non-small cell lung cancer. Nature Communications. 11: 603. PMID 32001676 DOI: 10.1038/s41467-019-14273-0   
2020 Suzuki T. [Research on Analysis of Final Diagnosis and Prognostic Factors, and Development of New Therapeutic Drugs for Malignant Tumors (Especially Malignant Pediatric Tumors)]. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 140: 229-271. PMID 32009046 DOI: 10.1248/yakushi.19-00178   
2020 Alghamri MS, Núñez FJ, Kamran N, Carney S, Altshuler D, Lowenstein PR, Castro MG. Functional characterization of tumor antigen-specific T-cells isolated from the tumor microenvironment of sleeping beauty induced murine glioma models. Methods in Enzymology. 631: 91-106. PMID 31948569 DOI: 10.1016/bs.mie.2019.05.032   
2020 Jewett A, Kos J, Kaur K, Safaei T, Sutanto C, Chen W, Wong P, Namagerdi AK, Fang C, Fong Y, Ko MW. Natural Killer Cells: Diverse Functions in Tumor Immunity and Defects in Pre-neoplastic and Neoplastic Stages of Tumorigenesis. Molecular Therapy Oncolytics. 16: 41-52. PMID 31930165 DOI: 10.1016/j.omto.2019.11.002   
2020 Atsou K, Anjuère F, Braud VM, Goudon T. A size and space structured model describing interactions of tumor cells with immune cells reveals cancer persistent equilibrium states in tumorigenesis. Journal of Theoretical Biology. 490: 110163. PMID 31981572 DOI: 10.1016/j.jtbi.2020.110163   
2020 Lim GJ, Kang SJ, Lee JY. Novel invasion indices quantify the feed-forward facilitation of tumor invasion by macrophages. Scientific Reports. 10: 718. PMID 31959808 DOI: 10.1038/s41598-020-57517-6   
2020 Byun WS, Kim S, Shin YH, Kim WK, Oh DC, Lee SK. Antitumor Activity of Ohmyungsamycin A through the Regulation of the Skp2-p27 Axis and MCM4 in Human Colorectal Cancer Cells. Journal of Natural Products. PMID 31894983 DOI: 10.1021/acs.jnatprod.9b00918   
2020 Luo X, Han G, Lu R, Guan S, Wang Y, Ju L, Chen L, Shao J, Bian Z. Transmembrane protein 106C promotes the development of hepatocellular carcinoma. Journal of Cellular Biochemistry. PMID 32037603 DOI: 10.1002/jcb.29678   
2020 Girotti MR, Salatino M, Dalotto-Moreno T, Rabinovich GA. Sweetening the hallmarks of cancer: Galectins as multifunctional mediators of tumor progression. The Journal of Experimental Medicine. 217. PMID 31873723 DOI: 10.1084/jem.20182041   
2020 Yang K, Tang XJ, Xu FF, Liu JH, Tan YQ, Gao L, Sun Q, Ding X, Liu BH, Chen QX. PI3K/mTORC1/2 inhibitor PQR309 inhibits proliferation and induces apoptosis in human glioblastoma cells. Oncology Reports. PMID 32020210 DOI: 10.3892/or.2020.7472   
2020 Xu F, Liu Z, Liu R, Lu C, Wang L, Mao W, Zhu Q, Shou H, Zhang K, Li Y, Chu Y, Gu J, Ge D. Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma. Cell Communication and Signaling : Ccs. 18: 17. PMID 32014008 DOI: 10.1186/s12964-020-0510-8   
2020 Lu Z, Bi J, Wan X. Artemisinin sensitizes tumor cells to NK cell-mediated cytolysis. Biochemical and Biophysical Research Communications. PMID 32007276 DOI: 10.1016/j.bbrc.2020.01.094   
2020 McCall KD, Muccioli M, Benencia F. Toll-Like Receptors Signaling in the Tumor Microenvironment. Advances in Experimental Medicine and Biology. 1223: 81-97. PMID 32030686 DOI: 10.1007/978-3-030-35582-1_5   
2020 Ahmad A, Ahsan H. Ras mediated activation of NF-κB and DNA damage response in carcinogenesis. Cancer Investigation. 1-58. PMID 31971023 DOI: 10.1080/07357907.2020.1721523   
2020 Stampouloglou E, Cheng N, Federico A, Slaby E, Monti S, Szeto GL, Varelas X. Yap suppresses T-cell function and infiltration in the tumor microenvironment. Plos Biology. 18: e3000591. PMID 31929526 DOI: 10.1371/journal.pbio.3000591   
2020 Nisar S, Hashem S, Macha MA, Yadav SK, Muralitharan S, Azeez L, Sageena G, Al-Naemi H, Haris M, Bhat AA. Exploring Dysregulated Signaling Pathways in Cancer. Current Pharmaceutical Design. PMID 31939726 DOI: 10.2174/1381612826666200115095937   
2020 Singh S, Ray LA, Shahi Thakuri P, Tran S, Konopka MC, Luker GD, Tavana H. Organotypic breast tumor model elucidates dynamic remodeling of tumor microenvironment. Biomaterials. 238: 119853. PMID 32062146 DOI: 10.1016/j.biomaterials.2020.119853   
2020 Gutmann DH. The Sociobiology of Brain Tumors. Advances in Experimental Medicine and Biology. 1225: 115-125. PMID 32030651 DOI: 10.1007/978-3-030-35727-6_8   
2020 Bhaduri A, Di Lullo E, Jung D, Müller S, Crouch EE, Espinosa CS, Ozawa T, Alvarado B, Spatazza J, Cadwell CR, Wilkins G, Velmeshev D, Liu SJ, Malatesta M, Andrews MG, et al. Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma. Cell Stem Cell. 26: 48-63.e6. PMID 31901251 DOI: 10.1016/j.stem.2019.11.015   
2020 Jeong YK, Oh JY, Yoo JK, Lim SH, Kim EH. The Biofunctional Effects of Mesima as a Radiosensitizer for Hepatocellular Carcinoma. International Journal of Molecular Sciences. 21. PMID 32013255 DOI: 10.3390/ijms21030871   
2020 Dong Y, Wang Z, Shi Q. Liquid Biopsy-Based Single-Cell Transcriptome Profiling Characterizes Heterogeneity of Disseminated Tumor Cells from Lung Adenocarcinoma. Proteomics. e1900224. PMID 31960581 DOI: 10.1002/pmic.201900224   
2020 Wang X, Chang H, Gao G, Su B, Deng Q, Zhou H, Wang Q, Lin Y, Ding Y. Silencing of PRDM5 increases cell proliferation and inhibits cell apoptosis in Glioma. The International Journal of Neuroscience. 1-19. PMID 32083978 DOI: 10.1080/00207454.2020.1733563   
2020 Luo Y, Yang J, Yu J, Liu X, Yu C, Hu J, Shi H, Ma X. Long Non-coding RNAs: Emerging Roles in the Immunosuppressive Tumor Microenvironment. Frontiers in Oncology. 10: 48. PMID 32083005 DOI: 10.3389/fonc.2020.00048   
2020 Ergul M, Aktan F, Yildiz MT, Tutar Y. Perturbation of HSP Network in MCF-7 Breast Cancer Cell Line Triggers Inducible HSP70 Expression and Leads to Tumor Suppression. Anti-Cancer Agents in Medicinal Chemistry. PMID 32053081 DOI: 10.2174/1871520620666200213102210   
2020 Foote JB, Sarvesh S, Emens LA. Cytokine profiling of tumor-infiltrating T lymphocytes by flow cytometry. Methods in Enzymology. 631: 1-20. PMID 31948543 DOI: 10.1016/bs.mie.2019.08.015   
2020 Egen JG, Ouyang W, Wu LC. Human Anti-tumor Immunity: Insights from Immunotherapy Clinical Trials. Immunity. 52: 36-54. PMID 31940272 DOI: 10.1016/j.immuni.2019.12.010   
2020 Durante MA, Rodriguez DA, Kurtenbach S, Kuznetsov JN, Sanchez MI, Decatur CL, Snyder H, Feun LG, Livingstone AS, Harbour JW. Single-cell analysis reveals new evolutionary complexity in uveal melanoma. Nature Communications. 11: 496. PMID 31980621 DOI: 10.1038/s41467-019-14256-1   
2020 Feng J, Mo J, Zhang A, Liu D, Zhou L, Hang T, Yang C, Wu Q, Xia D, Wen R, Yang J, Feng Y, Huang Y, Hu N, He G, et al. Antibody-free isolation and regulation of adherent cancer cells via hybrid branched microtube-sandwiched hydrodynamic system. Nanoscale. PMID 32068774 DOI: 10.1039/d0nr00153h   
2020 Ou X, Lv W. Metabolic changes and interaction of tumor cell, myeloid-derived suppressor cell and T cell in hypoxic microenvironment. Future Oncology (London, England). PMID 32067476 DOI: 10.2217/fon-2019-0692   
2020 Roussel M, Lhomme F, Roe CE, Bartkowiak T, Gravelle P, Laurent C, Fest T, Irish JM. Mass cytometry defines distinct immune profile in germinal center B-cell lymphomas. Cancer Immunology, Immunotherapy : Cii. PMID 31919622 DOI: 10.1007/s00262-019-02464-z   
2020 Wang J, Shen F, Yao Y, Wang LL, Zhu Y, Hu J. Adoptive Cell Therapy: A Novel and Potential Immunotherapy for Glioblastoma. Frontiers in Oncology. 10: 59. PMID 32083009 DOI: 10.3389/fonc.2020.00059   
2020 Millar DG, Ramjiawan RR, Kawaguchi K, Gupta N, Chen J, Zhang S, Nojiri T, Ho WW, Aoki S, Jung K, Chen I, Shi F, Heather JM, Shigeta K, Morton LT, et al. Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy. Nature Biotechnology. PMID 32042168 DOI: 10.1038/s41587-019-0404-8   
2020 Garcia-Fabiani MB, Comba A, Kadiyala P, Haase S, Núñez FJ, Altshuler D, Lowenstein PR, Castro MG. Isolation and characterization of immune cells from the tumor microenvironment of genetically engineered pediatric high-grade glioma models using the sleeping beauty transposon system. Methods in Enzymology. 632: 369-388. PMID 32000905 DOI: 10.1016/bs.mie.2019.05.023   
2020 Amschler K, Schön MP. Modulating Tumor Cell Functions by Tunable Nanopatterned Ligand Presentation. Nanomaterials (Basel, Switzerland). 10. PMID 31991896 DOI: 10.3390/nano10020212   
2020 Decamps C, Privé F, Bacher R, Jost D, Waguet A, , Houseman EA, Lurie E, Lutsik P, Milosavljevic A, Scherer M, Blum MGB, Richard M. Guidelines for cell-type heterogeneity quantification based on a comparative analysis of reference-free DNA methylation deconvolution software. Bmc Bioinformatics. 21: 16. PMID 31931698 DOI: 10.1186/s12859-019-3307-2   
2020 Liu A, Curran MA. Tumor hypermetabolism confers resistance to immunotherapy. Seminars in Cancer Biology. PMID 31982512 DOI: 10.1016/j.semcancer.2020.01.009   
2020 Rabé M, Dumont S, Álvarez-Arenas A, Janati H, Belmonte-Beitia J, Calvo GF, Thibault-Carpentier C, Séry Q, Chauvin C, Joalland N, Briand F, Blandin S, Scotet E, Pecqueur C, Clairambault J, et al. Identification of a transient state during the acquisition of temozolomide resistance in glioblastoma. Cell Death & Disease. 11: 19. PMID 31907355 DOI: 10.1038/s41419-019-2200-2   
2020 Khan MA, Zubair H, Anand S, Srivastava SK, Singh S, Singh AP. Dysregulation Of Metabolic Enzymes In Tumor And Stromal Cells: Role In Oncogenesis And Therapeutic Opportunities. Cancer Letters. PMID 31923436 DOI: 10.1016/j.canlet.2020.01.003   
2020 Zhang W, Hu X, Liang J, Zhu Y, Zeng B, Feng L, Zhao C, Liu S, Liu B, Zhang K. oHSV2 Can Target Murine Colon Carcinoma by Altering the Immune Status of the Tumor Microenvironment and Inducing Antitumor Immunity. Molecular Therapy Oncolytics. 16: 158-171. PMID 32055679 DOI: 10.1016/j.omto.2019.12.012   
2020 Carter KP, Segall JE, Cox D. Microscopic Methods for Analysis of Macrophage-Induced Tunneling Nanotubes. Methods in Molecular Biology (Clifton, N.J.). 2108: 273-279. PMID 31939188 DOI: 10.1007/978-1-0716-0247-8_23   
2020 Kang R, Zeh H, Lotze M, Tang D. The Multifaceted Effects of Autophagy on the Tumor Microenvironment. Advances in Experimental Medicine and Biology. 1225: 99-114. PMID 32030650 DOI: 10.1007/978-3-030-35727-6_7   
2020 Woźniak M, Pawelak A, Makuch S, Martuszewski A, Winograd K, Ziółkowski P, Agrawal S. Osteopontin is differentially expressed in renal cell tumors. Journal of Histotechnology. 1-7. PMID 31914887 DOI: 10.1080/01478885.2019.1710041   
2020 Wu J, Wang Y, Jiang Z. TNFSF9 Is a Prognostic Biomarker and Correlated with Immune Infiltrates in Pancreatic Cancer. Journal of Gastrointestinal Cancer. PMID 32077004 DOI: 10.1007/s12029-020-00371-6