| Year |
Citation |
Score |
| 2024 |
Giancotti LA, Lauro F, Olayide I, Zhang J, Arnatt CK, Salvemini D. 12-(S)-Hydroxyeicosatetraenoic acid and GPR31 signaling in spinal cord in neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics. PMID 38278551 DOI: 10.1124/jpet.123.001853 |
0.351 |
|
| 2023 |
Jacobson KA, Salvemini D. Editorial: Small molecules and biologics for future purinergic therapeutics. Purinergic Signalling. 19: 465-466. PMID 37676356 DOI: 10.1007/s11302-023-09964-9 |
0.365 |
|
| 2023 |
Wen Z, Pramanik A, Lewicki SA, Jung YH, Gao ZG, Randle JCR, Cronin C, Chen Z, Giancotti LA, Whitehead GS, Liang BT, Breton S, Salvemini D, Cook DN, Jacobson KA. Alicyclic Ring Size Variation of 4-Phenyl-2-naphthoic Acid Derivatives as P2Y Receptor Antagonists. Journal of Medicinal Chemistry. PMID 37382926 DOI: 10.1021/acs.jmedchem.3c00664 |
0.424 |
|
| 2022 |
Salvemini D, Doyle TM. Targeting neuroinflammation in neuropathic pain and opioid use. The Journal of Experimental Medicine. 220. PMID 36562735 DOI: 10.1084/jem.20221244 |
0.335 |
|
| 2022 |
Sgambellone S, Marri S, Catarinicchia S, Pini A, Tosh DK, Jacobson KA, Masini E, Salvemini D, Lucarini L. Adenosine A Receptor (AAR) Agonist for the Treatment of Bleomycin-Induced Lung Fibrosis in Mice. International Journal of Molecular Sciences. 23. PMID 36362112 DOI: 10.3390/ijms232113300 |
0.377 |
|
| 2022 |
Wen Z, Salmaso V, Jung YH, Phung NB, Gopinatth V, Shah Q, Patterson AT, Randle JCR, Chen Z, Salvemini D, Lieberman DI, Whitehead GS, Karcz TP, Cook DN, Jacobson KA. Bridged Piperidine Analogues of a High Affinity Naphthalene-Based P2YR Antagonist. Journal of Medicinal Chemistry. PMID 35113556 DOI: 10.1021/acs.jmedchem.1c01964 |
0.36 |
|
| 2022 |
Singh AK, Mahalingam R, Squillace S, Jacobson KA, Tosh DK, Dharmaraj S, Farr SA, Kavelaars A, Salvemini D, Heijnen CJ. Targeting the A adenosine receptor to prevent and reverse chemotherapy-induced neurotoxicities in mice. Acta Neuropathologica Communications. 10: 11. PMID 35093182 DOI: 10.1186/s40478-022-01315-w |
0.442 |
|
| 2022 |
Braden K, Stratton HJ, Salvemini D, Khanna R. Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces and prevents pain chronification in a mouse model of oxaliplatin-induced neuropathic pain. Neurobiology of Pain (Cambridge, Mass.). 11: 100082. PMID 35024498 DOI: 10.1016/j.ynpai.2021.100082 |
0.325 |
|
| 2021 |
Ilari S, Lauro F, Giancotti LA, Malafoglia V, Dagostino C, Gliozzi M, Condemi A, Maiuolo J, Oppedisano F, Palma E, Tomino C, Salvemini D, Mollace V, Muscoli C. The Protective Effect of Bergamot Polyphenolic Fraction (BPF) on Chemotherapy-Induced Neuropathic Pain. Pharmaceuticals (Basel, Switzerland). 14. PMID 34681199 DOI: 10.3390/ph14100975 |
0.332 |
|
| 2021 |
Coppi E, Cherchi F, Lucarini E, Ghelardini C, Pedata F, Jacobson KA, Di Cesare Mannelli L, Pugliese AM, Salvemini D. Uncovering the Mechanisms of Adenosine Receptor-Mediated Pain Control: Focus on the A Receptor Subtype. International Journal of Molecular Sciences. 22. PMID 34360719 DOI: 10.3390/ijms22157952 |
0.529 |
|
| 2021 |
Leduc-Pessah H, Xu C, Fan CY, Dalgarno R, Kohro Y, Sparanese S, Burke NN, Jacobson KA, Altier C, Salvemini D, Trang T. Spinal A adenosine receptor activation acutely restores morphine antinociception in opioid tolerant male rats. Journal of Neuroscience Research. PMID 34075613 DOI: 10.1002/jnr.24869 |
0.417 |
|
| 2021 |
Luongo L, Guida F, Maione S, Jacobson KA, Salvemini D. Adenosine Metabotropic Receptors in Chronic Pain Management. Frontiers in Pharmacology. 12: 651038. PMID 33935761 DOI: 10.3389/fphar.2021.651038 |
0.46 |
|
| 2021 |
Jung YH, Salmaso V, Wen Z, Bennett JM, Phung NB, Lieberman DI, Gopinatth V, Randle JCR, Chen Z, Salvemini D, Karcz TP, Cook DN, Jacobson KA. Structure-Activity Relationship of Heterocyclic P2Y Receptor Antagonists: Removal of the Zwitterionic Character with Piperidine Bioisosteres. Journal of Medicinal Chemistry. PMID 33787273 DOI: 10.1021/acs.jmedchem.1c00164 |
0.402 |
|
| 2021 |
Durante M, Squillace S, Lauro F, Giancotti LA, Coppi E, Cherchi F, Di Cesare Mannelli L, Ghelardini C, Kolar G, Wahlman C, Opejin A, Xiao C, Reitman ML, Tosh DK, Hawiger D, ... ... Salvemini D, et al. Adenosine A3 agonists reverse neuropathic pain via T cell-mediated production of IL-10. The Journal of Clinical Investigation. PMID 33621215 DOI: 10.1172/JCI139299 |
0.405 |
|
| 2020 |
Ilari S, Dagostino C, Malafoglia V, Lauro F, Giancotti LA, Spila A, Proietti S, Ventrice D, Rizzo M, Gliozzi M, Palma E, Guadagni F, Salvemini D, Mollace V, Muscoli C. Protective Effect of Antioxidants in Nitric Oxide/COX-2 Interaction during Inflammatory Pain: The Role of Nitration. Antioxidants (Basel, Switzerland). 9. PMID 33339104 DOI: 10.3390/antiox9121284 |
0.317 |
|
| 2020 |
Ilari S, Giancotti LA, Lauro F, Gliozzi M, Malafoglia V, Palma E, Tafani M, Russo MA, Tomino C, Fini M, Salvemini D, Mollace V, Muscoli C. Natural Antioxidant Control of Neuropathic Pain-Exploring the Role of Mitochondrial SIRT3 Pathway. Antioxidants (Basel, Switzerland). 9. PMID 33182469 DOI: 10.3390/antiox9111103 |
0.317 |
|
| 2020 |
Doyle TM, Hutchinson MR, Braden K, Janes K, Staikopoulos V, Chen Z, Neumann WL, Spiegel S, Salvemini D. Sphingosine-1-phosphate receptor subtype 1 activation in the central nervous system contributes to morphine withdrawal in rodents. Journal of Neuroinflammation. 17: 314. PMID 33092620 DOI: 10.1186/s12974-020-01975-2 |
0.606 |
|
| 2020 |
Squillace S, Spiegel S, Salvemini D. Targeting the Sphingosine-1-Phosphate Axis for Developing Non-narcotic Pain Therapeutics. Trends in Pharmacological Sciences. PMID 33010954 DOI: 10.1016/j.tips.2020.09.006 |
0.316 |
|
| 2020 |
Braden K, Giancotti LA, Chen Z, DeLeon C, Latzo N, Boehm T, D'Cunha N, Thompson BM, Doyle TM, McDonald JG, Walker JK, Kolar GR, Arnatt CK, Salvemini D. GPR183-oxysterol axis in spinal cord contributes to neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics. PMID 32913007 DOI: 10.1124/Jpet.120.000105 |
0.453 |
|
| 2020 |
Jung YH, Yu J, Wen Z, Salmaso V, Karcz TP, Phung NB, Chen Z, Duca S, Bennett JM, Dudas S, Salvemini D, Gao ZG, Cook DN, Jacobson KA. Exploration of Alternative Scaffolds for P2Y Receptor Antagonists Containing a Biaryl Core. Journal of Medicinal Chemistry. PMID 32787142 DOI: 10.1021/Acs.Jmedchem.0C00745 |
0.499 |
|
| 2020 |
Suresh RR, Jain S, Chen Z, Tosh DK, Ma Y, Podszun MC, Rotman Y, Salvemini D, Jacobson KA. Design and in vivo activity of A adenosine receptor agonist prodrugs. Purinergic Signalling. PMID 32720036 DOI: 10.1007/S11302-020-09715-0 |
0.481 |
|
| 2020 |
Mufti F, Jung YH, Giancotti LA, Yu J, Chen Z, Phung NB, Jacobson KA, Salvemini D. P2Y Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model. Acs Medicinal Chemistry Letters. 11: 1281-1286. PMID 32551012 DOI: 10.1021/Acsmedchemlett.0C00115 |
0.564 |
|
| 2020 |
Doyle TM, Largent-Milnes TM, Chen Z, Staikopoulos V, Esposito E, Delgarno R, Fan C, Tosh DK, Cuzzocrea S, Jacobson KA, Trang T, Hutchinson MR, Bennett GJ, Vanderah TW, Salvemini D.
The Journal of Pharmacology and Experimental Therapeutics. PMID 32434943 DOI: 10.1124/Jpet.120.000004 |
0.56 |
|
| 2020 |
Ilari S, Giancotti LA, Lauro F, Dagostino C, Gliozzi M, Malafoglia V, Sansone L, Palma E, Tafani M, Russo MA, Tomino C, Fini M, Salvemini D, Mollace V, Muscoli C. Antioxidant modulation of sirtuin 3 during acute inflammatory pain: The ROS control. Pharmacological Research. 157: 104851. PMID 32423865 DOI: 10.1016/J.Phrs.2020.104851 |
0.401 |
|
| 2020 |
Lucarini E, Coppi E, Micheli L, Parisio C, Vona A, Cherchi F, Pugliese AM, Pedata F, Failli P, Palomino S, Wahl J, Largent-Milnes TM, Vanderah TW, Tosh DK, Jacobson KA, ... Salvemini D, et al. Acute visceral pain relief mediated by A3AR agonists in rats: involvement of N-type voltage-gated calcium channels. Pain. PMID 32379223 DOI: 10.1097/J.Pain.0000000000001905 |
0.559 |
|
| 2020 |
Doyle TM, Janes K, Chen Z, Grace PM, Esposito E, Cuzzocrea S, Largent-Milnes TM, Neumann WL, Watkins LR, Spiegel S, Vanderah TW, Salvemini D. Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents. Pain. PMID 32301840 DOI: 10.1097/J.Pain.0000000000001888 |
0.667 |
|
| 2020 |
Jacobson KA, Giancotti LA, Lauro F, Mufti F, Salvemini D. Treatment of chronic neuropathic pain: purine receptor modulation. Pain. PMID 32187120 DOI: 10.1097/J.Pain.0000000000001857 |
0.582 |
|
| 2020 |
Yosten GL, Harada CM, Haddock CJ, Giancotti LA, Kolar GR, Patel R, Guo C, Chen Z, Zhang J, Doyle TM, Dickenson AH, Samson WK, Salvemini D. GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents. The Journal of Clinical Investigation. PMID 31999650 DOI: 10.1172/Jci133270 |
0.428 |
|
| 2020 |
Latzo NG, Braden K, Giancotti L, Chen Z, DeLeon C, Boehm T, D’Cunha N, Luongo L, Doyle T, Kolar G, Walker J, Arnatt C, Salvemini D. Development of GPR183 Antagonists to Treat Neuropathic Pain The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09724 |
0.427 |
|
| 2019 |
Stockstill K, Wahlman C, Braden K, Chen Z, Yosten GL, Tosh DK, Jacobson KA, Doyle TM, Samson WK, Salvemini D. Sexually dimorphic therapeutic response in bortezomib-induced neuropathic pain reveals altered pain physiology in female rodents. Pain. PMID 31490328 DOI: 10.1097/J.Pain.0000000000001697 |
0.549 |
|
| 2019 |
Gliozzi M, Scicchitano M, Bosco F, Musolino V, Carresi C, Scarano F, Maiuolo J, Nucera S, Maretta A, Paone S, Mollace R, Ruga S, Zito MC, Macrì R, Oppedisano F, ... ... Salvemini D, et al. Modulation of Nitric Oxide Synthases by Oxidized LDLs: Role in Vascular Inflammation and Atherosclerosis Development. International Journal of Molecular Sciences. 20. PMID 31277498 DOI: 10.3390/Ijms20133294 |
0.324 |
|
| 2019 |
Chen Z, Doyle TM, Luongo L, Largent-Milnes TM, Giancotti LA, Kolar G, Squillace S, Boccella S, Walker JK, Pendleton A, Spiegel S, Neumann WL, Vanderah TW, Salvemini D. Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain. Proceedings of the National Academy of Sciences of the United States of America. PMID 31068460 DOI: 10.1073/Pnas.1820466116 |
0.374 |
|
| 2019 |
Coppi E, Cherchi F, Fusco I, Failli P, Vona A, Dettori I, Gaviano L, Lucarini E, Jacobson KA, Tosh DK, Salvemini D, Ghelardini C, Pedata F, Di Cesare Mannelli L, Pugliese AM. Adenosine A3 receptor activation inhibits pronociceptive N-type Ca2+ currents and cell excitability in dorsal root ganglion neurons. Pain. 160: 1103-1118. PMID 31008816 DOI: 10.1097/J.Pain.0000000000001488 |
0.5 |
|
| 2019 |
Coppi E, Cherchi F, Fusco I, Failli P, Vona A, Dettori I, Gaviano L, Lucarini E, Jacobson KA, Tosh DK, Salvemini D, Ghelardini C, Pedata F, Di Cesare Mannelli L, Pugliese AM. Title: Adenosine A3 receptor activation inhibits pro-nociceptive N-type Ca2+ currents and cell excitability in dorsal root ganglion neurons. Pain. PMID 30938716 DOI: 10.1097/j.pain.0000000000001488 |
0.431 |
|
| 2018 |
Stockstill K, Doyle TM, Yan X, Chen Z, Janes K, Little JW, Braden K, Lauro F, Giancotti LA, Harada CM, Yadav R, Xiao WH, Lionberger JM, Neumann WL, Bennett GJ, ... ... Salvemini D, et al. Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain. The Journal of Experimental Medicine. PMID 29703731 DOI: 10.1084/Jem.20170584 |
0.732 |
|
| 2018 |
Luongo L, Salvemini D. Targeting metabotropic adenosine receptors for neuropathic pain: focus on A2A. Brain, Behavior, and Immunity. PMID 29499304 DOI: 10.1016/J.Bbi.2018.02.014 |
0.416 |
|
| 2018 |
Touchette JC, Little JW, Wilken GH, Salvemini D, Macarthur H. The neurotoxin DSP-4 induces hyperalgesia in rats that is accompanied by spinal oxidative stress and cytokine production. Neuroscience. PMID 29421433 DOI: 10.1016/J.Neuroscience.2018.01.058 |
0.601 |
|
| 2018 |
Wahlman C, Doyle TM, Little JW, Luongo L, Janes K, Chen Z, Esposito E, Tosh DK, Cuzzocrea S, Jacobson KA, Salvemini D. Chemotherapy-induced pain is promoted by enhanced spinal adenosine kinase levels via astrocyte-dependent mechanisms. Pain. PMID 29419652 DOI: 10.1097/J.Pain.0000000000001177 |
0.757 |
|
| 2018 |
Squillace S, Durante M, Opejin A, Hawiger D, Tosh D, Jacobson K, Salvemini D. CD4 + T cells and IL-10 are required for the beneficial effects exerted by A 3 AR agonists in neuropathic pain The Journal of Pain. 19: S81-S82. DOI: 10.1016/J.Jpain.2017.12.197 |
0.507 |
|
| 2017 |
Salvemini D, Jacobson KA. Highly selective A3 adenosine receptor agonists relieve chronic neuropathic pain. Expert Opinion On Therapeutic Patents. PMID 28604241 DOI: 10.1080/13543776.2017.1341018 |
0.553 |
|
| 2017 |
Grenald SA, Doyle TM, Zhang H, Slosky LM, Chen Z, Largent-Milnes TM, Spiegel S, Vanderah TW, Salvemini D. Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation. Pain. PMID 28570482 DOI: 10.1097/J.Pain.0000000000000965 |
0.392 |
|
| 2017 |
Petrelli R, Scortichini M, Kachler S, Boccella S, Cerchia C, Torquati I, Del Bello F, Salvemini D, Novellino E, Luongo L, Maione S, Jacobson KA, Lavecchia A, Klotz KN, Cappellacci L. Exploring the role of N(6)-substituents in potent dual acting 5'-C-ethyl-tetrazolyl-adenosine derivatives: synthesis, binding, functional assays and antinociceptive effects in mice. Journal of Medicinal Chemistry. PMID 28447789 DOI: 10.1021/Acs.Jmedchem.7B00291 |
0.517 |
|
| 2017 |
Tosh DK, Janowsky A, Eshleman AJ, Warnick E, Gao ZG, Chen Z, Gizewski E, Auchampach JA, Salvemini D, Jacobson KA. Scaffold Repurposing of Nucleosides (Adenosine Receptor Agonists): Enhanced Activity at the Human Dopamine and Norepinephrine Sodium Symporters. Journal of Medicinal Chemistry. PMID 28319392 DOI: 10.1021/Acs.Jmedchem.7B00141 |
0.446 |
|
| 2017 |
Durante M, Squillace S, Stockstill K, Wahlman C, Masini E, Tosh D, Jacobson K, Salvemini D. (193) Contribution of IL-10 and T cells in beneficial effects exerted by A 3 adenosine receptor agonists in blocking and reversing neuropathic pain The Journal of Pain. 18: S24. DOI: 10.1016/J.Jpain.2017.02.100 |
0.55 |
|
| 2017 |
Zhang H, Doyle T, Grenald S, Jacobson K, Salvemini D, Vanderah T. (192) Targeting A3 adenosine receptor in HIV-1 gp120-induced neuropathic pain The Journal of Pain. 18: S24. DOI: 10.1016/J.Jpain.2017.02.099 |
0.447 |
|
| 2017 |
Harada C, Chen Z, Stockstill L, Wahlman C, Kolar G, Smason W, Yosten G, Salvemini D. (187) Identification of spinal GPR160 as a novel protein promoting chronic neuropathic pain states The Journal of Pain. 18: S23. DOI: 10.1016/J.Jpain.2017.02.094 |
0.38 |
|
| 2017 |
Doyle T, Chen Z, Salvemini D. (182) Sphingosine 1-phosphate receptor subtype 1: a neuroinflammatory rheostat of the spinal cord in the development of chronic pain The Journal of Pain. 18: S21-S22. DOI: 10.1016/J.Jpain.2017.02.089 |
0.393 |
|
| 2016 |
Grace PM, Gaudet AD, Staikopoulos V, Maier SF, Hutchinson MR, Salvemini D, Watkins LR. Nitroxidative Signaling Mechanisms in Pathological Pain. Trends in Neurosciences. PMID 27842920 DOI: 10.1016/J.Tins.2016.10.003 |
0.415 |
|
| 2016 |
Romero-Reyes M, Salvemini D. Cancer and orofacial pain. Medicina Oral, Patologia Oral Y Cirugia Bucal. 21: e665-e671. PMID 27694791 DOI: 10.4317/Medoral.21515 |
0.314 |
|
| 2016 |
Malafoglia V, Traversetti L, Del Grosso F, Scalici M, Lauro F, Russo V, Persichini T, Salvemini D, Mollace V, Fini M, Raffaeli W, Muscoli C, Colasanti M. Transient Receptor Potential Melastatin-3 (TRPM3) Mediates Nociceptive-Like Responses in Hydra vulgaris. Plos One. 11: e0151386. PMID 26974325 DOI: 10.1371/Journal.Pone.0151386 |
0.359 |
|
| 2016 |
Tosh DK, Ciancetta A, Warnick E, O'Connor R, Chen Z, Gizewski E, Crane S, Gao ZG, Auchampach JA, Salvemini D, Jacobson KA. Purine (N)-Methanocarba Nucleoside Derivatives Lacking an Exocyclic Amine as Selective A3 Adenosine Receptor Agonists. Journal of Medicinal Chemistry. PMID 26890707 DOI: 10.1021/Acs.Jmedchem.5B01998 |
0.459 |
|
| 2016 |
Janes K, Symons-Liguori AM, Jacobson KA, Salvemini D. Identification of A3 adenosine receptor agonists as novel non-narcotic analgesics. British Journal of Pharmacology. PMID 26804983 DOI: 10.1111/Bph.13446 |
0.704 |
|
| 2015 |
Carlin JL, Tosh DK, Xiao C, Pinol RA, Chen Z, Salvemini D, Gavrilova O, Jacobson KA, Reitman ML. Peripheral Adenosine A3 Receptor Activation Causes Regulated Hypothermia in Mice that is Dependent on Central Histamine H1 Receptors. The Journal of Pharmacology and Experimental Therapeutics. PMID 26606937 DOI: 10.1124/Jpet.115.229872 |
0.514 |
|
| 2015 |
Trang T, Al-Hasani R, Salvemini D, Salter MW, Gutstein H, Cahill CM. Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13879-88. PMID 26468188 DOI: 10.1523/Jneurosci.2711-15.2015 |
0.423 |
|
| 2015 |
Tosh DK, Paoletta S, Chen Z, Crane S, Lloyd J, Gao ZG, Gizewski ET, Auchampach JA, Salvemini D, Jacobson KA. Structure-Based Design, Synthesis by Click Chemistry and in Vivo Activity of Highly Selective A3 Adenosine Receptor Agonists. Medchemcomm. 6: 555-563. PMID 26236460 DOI: 10.1039/C4Md00571F |
0.531 |
|
| 2015 |
Tosh DK, Crane S, Chen Z, Paoletta S, Gao ZG, Gizewski E, Auchampach JA, Salvemini D, Jacobson KA. Rigidified A3 Adenosine Receptor Agonists: 1-Deazaadenine Modification Maintains High in Vivo Efficacy. Acs Medicinal Chemistry Letters. 6: 804-8. PMID 26191370 DOI: 10.1021/Acsmedchemlett.5B00150 |
0.507 |
|
| 2015 |
Tosh DK, Padia J, Salvemini D, Jacobson KA. Efficient, large-scale synthesis and preclinical studies of MRS5698, a highly selective A3 adenosine receptor agonist that protects against chronic neuropathic pain. Purinergic Signalling. PMID 26111639 DOI: 10.1007/S11302-015-9459-2 |
0.547 |
|
| 2015 |
Luongo L, Malcangio M, Salvemini D, Starowicz K. Chronic pain: new insights in molecular and cellular mechanisms. Biomed Research International. 2015: 676725. PMID 25879035 DOI: 10.1155/2015/676725 |
0.401 |
|
| 2015 |
Ford A, Castonguay A, Cottet M, Little JW, Chen Z, Symons-Liguori AM, Doyle T, Egan TM, Vanderah TW, De Konnick Y, Tosh DK, Jacobson KA, Salvemini D. Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6057-67. PMID 25878279 DOI: 10.1523/Jneurosci.4495-14.2015 |
0.678 |
|
| 2015 |
Little JW, Ford A, Symons-Liguori AM, Chen Z, Janes K, Doyle T, Xie J, Luongo L, Tosh DK, Maione S, Bannister K, Dickenson AH, Vanderah TW, Porreca F, Jacobson KA, ... Salvemini D, et al. Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states. Brain : a Journal of Neurology. 138: 28-35. PMID 25414036 DOI: 10.1093/Brain/Awu330 |
0.783 |
|
| 2015 |
Janes K, Wahlman C, Little JW, Doyle T, Tosh DK, Jacobson KA, Salvemini D. Spinal neuroimmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy. Brain, Behavior, and Immunity. 44: 91-9. PMID 25220279 DOI: 10.1016/J.Bbi.2014.08.010 |
0.774 |
|
| 2015 |
Tosh DK, Paoletta S, Chen Z, Crane S, Lloyd J, Gao ZG, Gizewski ET, Auchampach JA, Salvemini D, Jacobson KA. Structure-based design, synthesis by click chemistry and in vivo activity of highly selective A3 adenosine receptor agonists Medchemcomm. 6: 555-563. DOI: 10.1039/c4md00571f |
0.393 |
|
| 2015 |
Lauro F, Ilari S, Giancotti LA, Morabito C, Malafoglia V, Gliozzi M, Palma E, Salvemini D, Muscoli C. The protective role of bergamot polyphenolic fraction on several animal models of pain Pharmanutrition. DOI: 10.1016/J.Phanu.2016.04.001 |
0.411 |
|
| 2015 |
Little J, Janes K, Chen Z, Wahlman C, Tosh D, Jacobson K, Salvemini D. (326) Supraspinal adenosine A3 receptor (A3AR) activation reverses chemotherapy-induced neuropathic pain through an IL-10 dependent mechanism The Journal of Pain. 16: S57. DOI: 10.1016/J.Jpain.2015.01.244 |
0.766 |
|
| 2015 |
Tosh DK, Padia J, Salvemini D, Jacobson KA. Efficient, large-scale synthesis and preclinical studies of MRS5698, a highly selective A3 adenosine receptor agonist that protects against chronic neuropathic pain Purinergic Signalling. DOI: 10.1007/s11302-015-9459-2 |
0.476 |
|
| 2014 |
Tosh DK, Finley A, Paoletta S, Moss SM, Gao ZG, Gizewski ET, Auchampach JA, Salvemini D, Jacobson KA. In vivo phenotypic screening for treating chronic neuropathic pain: modification of C2-arylethynyl group of conformationally constrained A3 adenosine receptor agonists. Journal of Medicinal Chemistry. 57: 9901-14. PMID 25422861 DOI: 10.1021/Jm501021N |
0.549 |
|
| 2014 |
Janes K, Esposito E, Doyle T, Cuzzocrea S, Tosh DK, Jacobson KA, Salvemini D. A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways. Pain. 155: 2560-7. PMID 25242567 DOI: 10.1016/J.Pain.2014.09.016 |
0.744 |
|
| 2014 |
Mollace V, Muscoli C, Dagostino C, Giancotti LA, Gliozzi M, Sacco I, Visalli V, Gratteri S, Palma E, Malara N, Musolino V, Carresi C, Muscoli S, Vitale C, Salvemini D, et al. The effect of peroxynitrite decomposition catalyst MnTBAP on aldehyde dehydrogenase-2 nitration by organic nitrates: role in nitrate tolerance. Pharmacological Research. 89: 29-35. PMID 25174989 DOI: 10.1016/J.Phrs.2014.07.007 |
0.351 |
|
| 2014 |
Tosh DK, Paoletta S, Chen Z, Moss SM, Gao ZG, Salvemini D, Jacobson KA. Extended N(6) substitution of rigid C2-arylethynyl nucleosides for exploring the role of extracellular loops in ligand recognition at the A3 adenosine receptor. Bioorganic & Medicinal Chemistry Letters. 24: 3302-6. PMID 24969016 DOI: 10.1016/J.Bmcl.2014.06.006 |
0.505 |
|
| 2014 |
Janes K, Little JW, Li C, Bryant L, Chen C, Chen Z, Kamocki K, Doyle T, Snider A, Esposito E, Cuzzocrea S, Bieberich E, Obeid L, Petrache I, Nicol G, ... ... Salvemini D, et al. The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. The Journal of Biological Chemistry. 289: 21082-97. PMID 24876379 DOI: 10.1074/Jbc.M114.569574 |
0.762 |
|
| 2014 |
Rajagopalan P, Tracey H, Chen Z, Bandyopadhyaya A, Veeraraghavan S, Rajagopalan DR, Salvemini D, McPhee I, Viswanadha S, Rajagopalan R. DDD-028: a potent potential non-opioid, non-cannabinoid analgesic for neuropathic and inflammatory pain. Bioorganic & Medicinal Chemistry Letters. 24: 3088-91. PMID 24863744 DOI: 10.1016/J.Bmcl.2014.05.016 |
0.475 |
|
| 2014 |
Paoletta S, Tosh DK, Salvemini D, Jacobson KA. Structural probing of off-target G protein-coupled receptor activities within a series of adenosine/adenine congeners. Plos One. 9: e97858. PMID 24859150 DOI: 10.1371/Journal.Pone.0097858 |
0.449 |
|
| 2014 |
Doyle T, Li C, Nicol G, Neumann W, Salvemini D. (341) Sphingosine 1-phosphate receptor 1 antagonism prevents morphine-induced antinociceptive tolerance and hyperalgesia The Journal of Pain. 15: S61. DOI: 10.1016/J.Jpain.2014.01.251 |
0.35 |
|
| 2014 |
Ilari S, Lauro F, Montagna C, Di Giacomo G, Rizza S, Cardaci S, Allegri M, De Gregori M, Dagostino C, Gliozzi M, Filomeni G, Salvemini D, Mollace V, Muscoli C. (339) Spontaneous pain response in S-nitrosoglutathione reductase (GSNOR) deficient mice: the role of S-nitrosylation The Journal of Pain. 15: S60. DOI: 10.1016/J.Jpain.2014.01.249 |
0.338 |
|
| 2014 |
Janes K, Doyle T, Cuzzocrea S, Bennett G, Salvemini D. (338) The role of peroxynitrite in peripheral nerve sensory axon mitotoxicity during chemotherapy-induced neuropathic pain The Journal of Pain. 15: S60. DOI: 10.1016/J.Jpain.2014.01.248 |
0.61 |
|
| 2014 |
Stockstill K, Janes K, Xiao W, Li C, Bryant L, Nicol G, Bennett G, Salvemini D. (337) Bortezomib-induced neuropathic pain is blocked and reversed by blocking the S1P/S1PR1 axis The Journal of Pain. 15: S60. DOI: 10.1016/J.Jpain.2014.01.247 |
0.651 |
|
| 2014 |
Maloy C, Janes K, Bryant L, Tosh D, Jacobson K, Salvemini D. (336) A3 adenosine receptor agonists reverse established oxaliplatin-induced neuropathic pain through an IL-10 mediated mechanism of action in spinal cord The Journal of Pain. 15: S60. DOI: 10.1016/J.Jpain.2014.01.246 |
0.712 |
|
| 2014 |
Little J, Chen Z, Ford A, Janes K, Doyle T, Tosh D, Jacobson K, Salvemini D. (297) Central adenosine A3 receptor (A3AR) activation reverses neuropathic pain The Journal of Pain. 15: S50. DOI: 10.1016/J.Jpain.2014.01.207 |
0.762 |
|
| 2013 |
Janes K, Doyle T, Bryant L, Esposito E, Cuzzocrea S, Ryerse J, Bennett GJ, Salvemini D. Bioenergetic deficits in peripheral nerve sensory axons during chemotherapy-induced neuropathic pain resulting from peroxynitrite-mediated post-translational nitration of mitochondrial superoxide dismutase. Pain. 154: 2432-40. PMID 23891899 DOI: 10.1016/J.Pain.2013.07.032 |
0.637 |
|
| 2013 |
Muscoli C, Dagostino C, Ilari S, Lauro F, Gliozzi M, Bardhi E, Palma E, Mollace V, Salvemini D. Posttranslational nitration of tyrosine residues modulates glutamate transmission and contributes to N-methyl-D-aspartate-mediated thermal hyperalgesia. Mediators of Inflammation. 2013: 950947. PMID 23864769 DOI: 10.1155/2013/950947 |
0.338 |
|
| 2013 |
Paoletta S, Tosh DK, Finley A, Gizewski ET, Moss SM, Gao ZG, Auchampach JA, Salvemini D, Jacobson KA. Rational design of sulfonated A3 adenosine receptor-selective nucleosides as pharmacological tools to study chronic neuropathic pain. Journal of Medicinal Chemistry. 56: 5949-63. PMID 23789857 DOI: 10.1021/Jm4007966 |
0.515 |
|
| 2013 |
Little JW, Cuzzocrea S, Bryant L, Esposito E, Doyle T, Rausaria S, Neumann WL, Salvemini D. Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance. Pain. 154: 978-86. PMID 23590939 DOI: 10.1016/J.Pain.2013.02.018 |
0.623 |
|
| 2013 |
Doyle T, Esposito E, Bryant L, Cuzzocrea S, Salvemini D. NADPH-oxidase 2 activation promotes opioid-induced antinociceptive tolerance in mice. Neuroscience. 241: 1-9. PMID 23454539 DOI: 10.1016/J.Neuroscience.2013.02.042 |
0.354 |
|
| 2013 |
Salvemini D, Kim SF, Mollace V. Reciprocal regulation of the nitric oxide and cyclooxygenase pathway in pathophysiology: relevance and clinical implications. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 304: R473-87. PMID 23389111 DOI: 10.1152/Ajpregu.00355.2012 |
0.354 |
|
| 2013 |
Finley A, Chen Z, Esposito E, Cuzzocrea S, Sabbadini R, Salvemini D. Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism. Plos One. 8: e55255. PMID 23372844 DOI: 10.1371/Journal.Pone.0055255 |
0.38 |
|
| 2013 |
Salvemini D, Doyle T, Kress M, Nicol G. Therapeutic targeting of the ceramide-to-sphingosine 1-phosphate pathway in pain. Trends in Pharmacological Sciences. 34: 110-8. PMID 23318139 DOI: 10.1016/J.Tips.2012.12.001 |
0.427 |
|
| 2013 |
Doyle T, Bryant L, Chen Z, Cuzzocrea S, Salvemini D. Morphine-induced antinociceptive tolerance and hyperalgesia is mediated through sphingosine 1-phosphate receptor 1-dependent p38 and neuroinflammatory mechanisms The Journal of Pain. 14: S42. DOI: 10.1016/J.Jpain.2013.01.503 |
0.353 |
|
| 2012 |
Little JW, Chen Z, Doyle T, Porreca F, Ghaffari M, Bryant L, Neumann WL, Salvemini D. Supraspinal peroxynitrite modulates pain signaling by suppressing the endogenous opioid pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10797-808. PMID 22875915 DOI: 10.1523/Jneurosci.6345-11.2012 |
0.644 |
|
| 2012 |
Doyle T, Chen Z, Muscoli C, Bryant L, Esposito E, Cuzzocrea S, Dagostino C, Ryerse J, Rausaria S, Kamadulski A, Neumann WL, Salvemini D. Targeting the overproduction of peroxynitrite for the prevention and reversal of paclitaxel-induced neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6149-60. PMID 22553021 DOI: 10.1523/Jneurosci.6343-11.2012 |
0.468 |
|
| 2012 |
Chen Z, Janes K, Chen C, Doyle T, Bryant L, Tosh DK, Jacobson KA, Salvemini D. Controlling murine and rat chronic pain through A3 adenosine receptor activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1855-65. PMID 22345405 DOI: 10.1096/Fj.11-201541 |
0.73 |
|
| 2012 |
Janes K, Neumann WL, Salvemini D. Anti-superoxide and anti-peroxynitrite strategies in pain suppression. Biochimica Et Biophysica Acta. 1822: 815-21. PMID 22200449 DOI: 10.1016/J.Bbadis.2011.12.008 |
0.659 |
|
| 2012 |
Little JW, Doyle T, Salvemini D. Reactive nitroxidative species and nociceptive processing: determining the roles for nitric oxide, superoxide, and peroxynitrite in pain. Amino Acids. 42: 75-94. PMID 20552384 DOI: 10.1007/S00726-010-0633-0 |
0.637 |
|
| 2011 |
Rausaria S, Ghaffari MM, Kamadulski A, Rodgers K, Bryant L, Chen Z, Doyle T, Shaw MJ, Salvemini D, Neumann WL. Retooling manganese(III) porphyrin-based peroxynitrite decomposition catalysts for selectivity and oral activity: a potential new strategy for treating chronic pain. Journal of Medicinal Chemistry. 54: 8658-69. PMID 22082008 DOI: 10.1021/Jm201233R |
0.373 |
|
| 2011 |
Doyle T, Chen Z, Obeid LM, Salvemini D. Sphingosine-1-phosphate acting via the S1P₁ receptor is a downstream signaling pathway in ceramide-induced hyperalgesia. Neuroscience Letters. 499: 4-8. PMID 21605625 DOI: 10.1016/J.Neulet.2011.05.018 |
0.373 |
|
| 2011 |
Samlowski WE, Kondapaneni M, Tharkar S, McGregor JR, Laubach VE, Salvemini D. Endothelial nitric oxide synthase is a key mediator of interleukin-2-induced hypotension and vascular leak syndrome. Journal of Immunotherapy (Hagerstown, Md. : 1997). 34: 419-27. PMID 21577143 DOI: 10.1097/Cji.0B013E31821Dcb50 |
0.323 |
|
| 2011 |
Doyle T, Chen Z, Muscoli C, Obeid LM, Salvemini D. Intraplantar-injected ceramide in rats induces hyperalgesia through an NF-κB- and p38 kinase-dependent cyclooxygenase 2/prostaglandin E2 pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2782-91. PMID 21551240 DOI: 10.1096/Fj.10-178095 |
0.345 |
|
| 2011 |
Salvemini D, Little JW, Doyle T, Neumann WL. Roles of reactive oxygen and nitrogen species in pain. Free Radical Biology & Medicine. 51: 951-66. PMID 21277369 DOI: 10.1016/J.Freeradbiomed.2011.01.026 |
0.623 |
|
| 2011 |
Doyle T, Finley A, Chen Z, Salvemini D. Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats. Pain. 152: 643-8. PMID 21239112 DOI: 10.1016/J.Pain.2010.12.011 |
0.405 |
|
| 2011 |
Nicol G, Langeslag M, Geisslinger G, Salvemini D, Kress M. 42 SPHINGOSINE 1-PHOSPHATE: REGULATOR OF INFLAMMATION AND PAIN European Journal of Pain Supplements. 5: 10-11. DOI: 10.1016/S1754-3207(11)70032-3 |
0.407 |
|
| 2011 |
Doyle T, Chen Z, Salvemini D. Peroxynitrite decomposition catalyst blocks paclitaxel-induced neuropathic pain: microarray analysis of spinal cord gene expression The Journal of Pain. 12: P37. DOI: 10.1016/J.Jpain.2011.02.148 |
0.356 |
|
| 2011 |
Little J, Chen Z, Doyle T, Porreca F, Salvemini D. Supraspinal descending facilitation of central sensitization depends on peroxynitrite regulation of opioid signaling The Journal of Pain. 12: P36. DOI: 10.1016/J.Jpain.2011.02.145 |
0.537 |
|
| 2010 |
Muscoli C, Doyle T, Dagostino C, Bryant L, Chen Z, Watkins LR, Ryerse J, Bieberich E, Neumman W, Salvemini D. Counter-regulation of opioid analgesia by glial-derived bioactive sphingolipids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15400-8. PMID 21084596 DOI: 10.1523/Jneurosci.2391-10.2010 |
0.409 |
|
| 2010 |
Doyle T, Bryant L, Muscoli C, Cuzzocrea S, Esposito E, Chen Z, Salvemini D. Spinal NADPH oxidase is a source of superoxide in the development of morphine-induced hyperalgesia and antinociceptive tolerance. Neuroscience Letters. 483: 85-9. PMID 20637262 DOI: 10.1016/J.Neulet.2010.07.013 |
0.384 |
|
| 2010 |
Chen Z, Muscoli C, Doyle T, Bryant L, Cuzzocrea S, Mollace V, Mastroianni R, Masini E, Salvemini D. NMDA-receptor activation and nitroxidative regulation of the glutamatergic pathway during nociceptive processing. Pain. 149: 100-6. PMID 20167432 DOI: 10.1016/J.Pain.2010.01.015 |
0.36 |
|
| 2010 |
Salvemini D, Neumann W. Targeting peroxynitrite driven nitroxidative stress with synzymes: A novel therapeutic approach in chronic pain management. Life Sciences. 86: 604-14. PMID 19576230 DOI: 10.1016/J.Lfs.2009.06.011 |
0.431 |
|
| 2009 |
Bryant L, Doyle T, Chen Z, Cuzzocrea S, Masini E, Vinci MC, Esposito E, Mazzon E, Petrusca DN, Petrache I, Salvemini D. Spinal ceramide and neuronal apoptosis in morphine antinociceptive tolerance. Neuroscience Letters. 463: 49-53. PMID 19631718 DOI: 10.1016/J.Neulet.2009.07.051 |
0.402 |
|
| 2009 |
Doyle T, Bryant L, Batinic-Haberle I, Little J, Cuzzocrea S, Masini E, Spasojevic I, Salvemini D. Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance Neuroscience. 164: 702-710. PMID 19607887 DOI: 10.1016/J.Neuroscience.2009.07.019 |
0.623 |
|
| 2009 |
Salvemini D, Neumann WL. Peroxynitrite: a strategic linchpin of opioid analgesic tolerance. Trends in Pharmacological Sciences. 30: 194-202. PMID 19261337 DOI: 10.1016/J.Tips.2008.12.005 |
0.419 |
|
| 2009 |
Ndengele MM, Cuzzocrea S, Masini E, Vinci MC, Esposito E, Muscoli C, Petrusca DN, Mollace V, Mazzon E, Li D, Petrache I, Matuschak GM, Salvemini D. Spinal ceramide modulates the development of morphine antinociceptive tolerance via peroxynitrite-mediated nitroxidative stress and neuroimmune activation. The Journal of Pharmacology and Experimental Therapeutics. 329: 64-75. PMID 19033555 DOI: 10.1124/Jpet.108.146290 |
0.432 |
|
| 2009 |
Salvemini D. Peroxynitrite and opiate antinociceptive tolerance: a painful reality. Archives of Biochemistry and Biophysics. 484: 238-44. PMID 19017525 DOI: 10.1016/J.Abb.2008.11.005 |
0.405 |
|
| 2009 |
Batinić-Haberle I, Cuzzocrea S, Rebouças JS, Ferrer-Sueta G, Mazzon E, Di Paola R, Radi R, Spasojević I, Benov L, Salvemini D. Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy. Free Radical Biology & Medicine. 46: 192-201. PMID 19007878 DOI: 10.1016/J.Freeradbiomed.2008.09.042 |
0.308 |
|
| 2009 |
Batinić-Haberle I, Ndengele MM, Cuzzocrea S, Rebouças JS, Spasojević I, Salvemini D. Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways. Free Radical Biology & Medicine. 46: 212-9. PMID 18983908 DOI: 10.1016/J.Freeradbiomed.2008.09.037 |
0.406 |
|
| 2009 |
Cuzzocrea S, Deigner HP, Genovese T, Mazzon E, Esposito E, Crisafulli C, Di Paola R, Bramanti P, Matuschak G, Salvemini D. Inhibition of ceramide biosynthesis ameliorates pathological consequences of spinal cord injury. Shock (Augusta, Ga.). 31: 634-44. PMID 18838947 DOI: 10.1097/Shk.0B013E3181891396 |
0.303 |
|
| 2008 |
Cuzzocrea S, Di Paola R, Genovese T, Mazzon E, Esposito E, Crisafulli C, Bramanti P, Salvemini D. Anti-inflammatory and anti-apoptotic effects of fumonisin B1, an inhibitor of ceramide synthase, in a rodent model of splanchnic ischemia and reperfusion injury. The Journal of Pharmacology and Experimental Therapeutics. 327: 45-57. PMID 18612046 DOI: 10.1124/Jpet.108.139808 |
0.306 |
|
| 2008 |
Ndengele MM, Cuzzocrea S, Esposito E, Mazzon E, Di Paola R, Matuschak GM, Salvemini D. Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3154-64. PMID 18497304 DOI: 10.1096/Fj.08-108159 |
0.432 |
|
| 2008 |
Kondapaneni M, McGregor JR, Salvemini D, Laubach VE, Samlowski WE. Inducible nitric oxide synthase (iNOS) is not required for IL-2-induced hypotension and vascular leak syndrome in mice. Journal of Immunotherapy (Hagerstown, Md. : 1997). 31: 325-33. PMID 18391763 DOI: 10.1097/Cji.0B013E31816112E8 |
0.308 |
|
| 2008 |
Masini E, Giannini L, Nistri S, Cinci L, Mastroianni R, Xu W, Comhair SA, Li D, Cuzzocrea S, Matuschak GM, Salvemini D. Ceramide: a key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation. The Journal of Pharmacology and Experimental Therapeutics. 324: 548-57. PMID 18042827 DOI: 10.1124/Jpet.107.131565 |
0.316 |
|
| 2007 |
Muscoli C, Cuzzocrea S, Ndengele MM, Mollace V, Porreca F, Fabrizi F, Esposito E, Masini E, Matuschak GM, Salvemini D. Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice. The Journal of Clinical Investigation. 117: 3530-9. PMID 17975673 DOI: 10.1172/Jci32420 |
0.422 |
|
| 2007 |
Cuzzocrea S, Salvemini D. Molecular mechanisms involved in the reciprocal regulation of cyclooxygenase and nitric oxide synthase enzymes Kidney International. 71: 290-297. PMID 17200681 DOI: 10.1038/Sj.Ki.5002058 |
0.332 |
|
| 2006 |
Salvemini D, Doyle TM, Cuzzocrea S. Superoxide, peroxynitrite and oxidative/nitrative stress in inflammation Biochemical Society Transactions. 34: 965-970. PMID 17052238 DOI: 10.1042/Bst0340965 |
0.33 |
|
| 2006 |
Cuzzocrea S, Mazzon E, Di Paola R, Esposito E, Macarthur H, Matuschak GM, Salvemini D. A role for nitric oxide-mediated peroxynitrite formation in a model of endotoxin-induced shock. The Journal of Pharmacology and Experimental Therapeutics. 319: 73-81. PMID 16815867 DOI: 10.1124/Jpet.106.108100 |
0.317 |
|
| 2005 |
Mollace V, Muscoli C, Masini E, Cuzzocrea S, Salvemini D. Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors. Pharmacological Reviews. 57: 217-52. PMID 15914468 DOI: 10.1124/Pr.57.2.1 |
0.361 |
|
| 2005 |
Ndengele MM, Muscoli C, Wang ZQ, Doyle TM, Matuschak GM, Salvemini D. Superoxide potentiates NF-kappaB activation and modulates endotoxin-induced cytokine production in alveolar macrophages. Shock (Augusta, Ga.). 23: 186-93. PMID 15665736 DOI: 10.1097/01.Shk.0000144130.36771.D6 |
0.307 |
|
| 2004 |
Muscoli C, Mollace V, Wheatley J, Masini E, Ndengele M, Wang ZQ, Salvemini D. Superoxide-mediated nitration of spinal manganese superoxide dismutase: a novel pathway in N-methyl-D-aspartate-mediated hyperalgesia. Pain. 111: 96-103. PMID 15327813 DOI: 10.1016/J.Pain.2004.06.004 |
0.393 |
|
| 2004 |
Muscoli C, Sacco I, Alecce W, Palma E, Nisticò R, Costa N, Clementi F, Rotiroti D, Romeo F, Salvemini D, Mehta JL, Mollace V. The protective effect of superoxide dismutase mimetic M40401 on balloon injury-related neointima formation: role of the lectin-like oxidized low-density lipoprotein receptor-1. The Journal of Pharmacology and Experimental Therapeutics. 311: 44-50. PMID 15220383 DOI: 10.1124/Jpet.104.068205 |
0.315 |
|
| 2004 |
Cuzzocrea S, Thiemermann C, Salvemini D. Potential therapeutic effect of antioxidant therapy in shock and inflammation. Current Medicinal Chemistry. 11: 1147-62. PMID 15134512 DOI: 10.2174/0929867043365396 |
0.347 |
|
| 2004 |
Wang ZQ, Porreca F, Cuzzocrea S, Galen K, Lightfoot R, Masini E, Muscoli C, Mollace V, Ndengele M, Ischiropoulos H, Salvemini D. A newly identified role for superoxide in inflammatory pain. The Journal of Pharmacology and Experimental Therapeutics. 309: 869-78. PMID 14988418 DOI: 10.1124/Jpet.103.064154 |
0.458 |
|
| 2004 |
Cuzzocrea S, Mazzon E, Dugo L, Di Paola R, Caputi AP, Salvemini D. Superoxide: A key player in hypertension Faseb Journal. 18: 94-101. PMID 14718390 DOI: 10.1096/Fj.03-0428Com |
0.312 |
|
| 2003 |
Muscoli C, Cuzzocrea S, Riley DP, Zweier JL, Thiemermann C, Wang ZQ, Salvemini D. On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies. British Journal of Pharmacology. 140: 445-60. PMID 14522841 DOI: 10.1038/Sj.Bjp.0705430 |
0.302 |
|
| 2003 |
Fries DM, Paxinou E, Themistocleous M, Swanberg E, Griendling KK, Salvemini D, Slot JW, Heijnen HF, Hazen SL, Ischiropoulos H. Expression of inducible nitric-oxide synthase and intracellular protein tyrosine nitration in vascular smooth muscle cells: role of reactive oxygen species. The Journal of Biological Chemistry. 278: 22901-7. PMID 12690103 DOI: 10.1074/Jbc.M210806200 |
0.314 |
|
| 2003 |
Tuder RM, Zhen L, Cho CY, Taraseviciene-Stewart L, Kasahara Y, Salvemini D, Voelkel NF, Flores SC. Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. American Journal of Respiratory Cell and Molecular Biology. 29: 88-97. PMID 12600822 DOI: 10.1165/Rcmb.2002-0228Oc |
0.311 |
|
| 2003 |
Salvemini D, Cuzzocrea S. Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine. Critical Care Medicine. 31: S29-38. PMID 12544974 DOI: 10.1097/00003246-200301001-00005 |
0.322 |
|
| 2003 |
Mollace V, Iannone M, Muscoli C, Palma E, Granato T, Rispoli V, Nisticò R, Rotiroti D, Salvemini D. The role of oxidative stress in paraquat-induced neurotoxicity in rats: protection by non peptidyl superoxide dismutase mimetic. Neuroscience Letters. 335: 163-6. PMID 12531458 DOI: 10.1016/S0304-3940(02)01168-0 |
0.318 |
|
| 2002 |
Salvemini D, Cuzzocrea S. Oxidative stress in septic shock and disseminated intravascular coagulation. Free Radical Biology & Medicine. 33: 1173-85. PMID 12398925 DOI: 10.1016/S0891-5849(02)00961-9 |
0.315 |
|
| 2002 |
Cuzzocrea S, Mazzon E, Dugo L, Serraino I, Di Paola R, Britti D, De Sarro A, Pierpaoli S, Caputi A, Masini E, Salvemini D. A role for superoxide in gentamicin-mediated nephropathy in rats. European Journal of Pharmacology. 450: 67-76. PMID 12176111 DOI: 10.1016/S0014-2999(02)01749-1 |
0.306 |
|
| 2002 |
Mollace V, Muscoli C, Iannone M, Palma E, Rotiroti D, Romeo F, Nisticò R, Salvemini D. Dexamethasone inhibits the inducible bioconversion of glyceryl trinitrate to nitric oxide. Journal of Cardiovascular Pharmacology. 39: 544-51. PMID 11904528 DOI: 10.1097/00005344-200204000-00010 |
0.336 |
|
| 2001 |
Cuzzocrea S, Mazzon E, Dugo L, Caputi AP, Riley DP, Salvemini D. Protective effects of M40403, a superoxide dismutase mimetic, in a rodent model of colitis European Journal of Pharmacology. 432: 79-89. PMID 11734191 DOI: 10.1016/S0014-2999(01)01427-3 |
0.305 |
|
| 2001 |
Salvemini D, Mazzon E, Dugo L, Riley DP, Serraino I, Caputi AP, Cuzzocrea S. Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403 British Journal of Pharmacology. 132: 815-827. PMID 11181422 DOI: 10.1038/Sj.Bjp.0703841 |
0.326 |
|
| 1999 |
Salvemini D, Riley DP, Lennon PJ, Wang ZQ, Currie MG, Macarthur H, Misko TP. Protective effects of a superoxide dismutase mimetic and peroxynitrite decomposition catalysts in endotoxin-induced intestinal damage. British Journal of Pharmacology. 127: 685-92. PMID 10401559 DOI: 10.1038/Sj.Bjp.0702604 |
0.309 |
|
| 1998 |
Salvemini D, Marino MH. Inducible nitric oxide synthase and inflammation Expert Opinion On Investigational Drugs. 7: 65-75. DOI: 10.1517/13543784.7.1.65 |
0.326 |
|
| 1997 |
Salvemini D. Regulation of cyclooxygenase enzymes by nitric oxide Cellular and Molecular Life Sciences. 53: 576-582. PMID 9312403 DOI: 10.1007/S000180050074 |
0.327 |
|
| 1996 |
Salvemini D, Wang ZQ, Bourdon DM, Stern MK, Currie MG, Manning PT. Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema European Journal of Pharmacology. 303: 217-220. PMID 8813572 DOI: 10.1016/0014-2999(96)00140-9 |
0.348 |
|
| 1996 |
Salvemini D, Wang ZQ, Wyatt PS, Bourdon DM, Marino MH, Manning PT, Currie MG. Nitric oxide: A key mediator in the early and late phase of carrageenan-induced rat paw inflammation British Journal of Pharmacology. 118: 829-838. PMID 8799551 DOI: 10.1111/J.1476-5381.1996.Tb15475.X |
0.341 |
|
| 1996 |
Salvemini D, Masferrer JL. Interactions of nitric oxide with cyclooxygenase: In vitro, ex vivo, and in vivo studies Methods in Enzymology. 269: 12-25. PMID 8791633 DOI: 10.1016/S0076-6879(96)69005-3 |
0.352 |
|
| 1996 |
Salvemini D, Currie MG, Mollace V. Nitric oxide-mediated cyclooxygenase activation. A key event in the antiplatelet effects of nitrovasodilators Journal of Clinical Investigation. 97: 2562-2568. PMID 8647949 DOI: 10.1172/Jci118704 |
0.365 |
|
| 1995 |
Salvemini D, Seibert K, Masferrer JL, Settle SL, Currie MG, Needleman P. Nitric Oxide Activates the Cyclooxygenase Pathway in Inflammation. American Journal of Therapeutics. 2: 616-619. PMID 11854836 DOI: 10.1097/00045391-199509000-00007 |
0.309 |
|
| 1995 |
Masferrer JL, Zweifel BS, Colburn SM, Ornberg RL, Salvemini D, Isakson P, Seibert K. The Role of Cyclooxygenase-2 in Inflammation. American Journal of Therapeutics. 2: 607-610. PMID 11854834 DOI: 10.1097/00045391-199509000-00005 |
0.308 |
|
| 1995 |
Salvemini D, Settle SL, Masferrer JL, Seibert K, Currie MG, Needleman P. Regulation of prostaglandin production by nitric oxide; an in vivo analysis. British Journal of Pharmacology. 114: 1171-8. PMID 7542531 DOI: 10.1111/J.1476-5381.1995.Tb13330.X |
0.32 |
|
| 1995 |
Salvemini D, Manning PT, Zweifel BS, Seibert K, Connor J, Currie MG, Needleman P, Masferrer JL. Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors. The Journal of Clinical Investigation. 96: 301-8. PMID 7542281 DOI: 10.1172/Jci118035 |
0.348 |
|
| 1994 |
Pistelli A, Mollace V, Nistico G, Salvemini D, Vane J. Nitroblue tetrazolium inhibits oxidation of glyceryl trinitrate to nitric oxide in bovine aortic smooth muscle cells Biochemical Pharmacology. 47: 1737-1742. PMID 8204090 DOI: 10.1016/0006-2952(94)90300-X |
0.522 |
|
| 1994 |
Salvemini D, Seibert K, Masferrer JL, Misko TP, Currie MG, Needleman P. Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. The Journal of Clinical Investigation. 93: 1940-7. PMID 7514189 DOI: 10.1172/Jci117185 |
0.337 |
|
| 1993 |
Salvemini D, Pistelli A, Vane J. Conversion of glyceryl trinitrate to nitric oxide in tolerant and non-tolerant smooth muscle and endothelial cells British Journal of Pharmacology. 108: 162-169. PMID 8381319 DOI: 10.1111/J.1476-5381.1993.Tb13457.X |
0.542 |
|
| 1993 |
Salvemini D, Pistelli A, Mollace V. Release of nitric oxide from glyceryl trinitrate by captopril but not enalaprilat: In vitro and in vivo studies British Journal of Pharmacology. 109: 430-436. PMID 8358544 DOI: 10.1111/J.1476-5381.1993.Tb13587.X |
0.347 |
|
| 1993 |
Salvemini D, Pistelli A, Anggard E. Vascular and anti-platelet actions of 1,2- and 1,3-glyceryl dinitrate British Journal of Pharmacology. 110: 937-942. PMID 8298817 DOI: 10.1111/J.1476-5381.1993.Tb13903.X |
0.329 |
|
| 1993 |
Salvemini D, Misko TP, Masferrer JL, Seibert K, Currie MG, Needleman P. Nitric oxide activates cyclooxygenase enzymes. Proceedings of the National Academy of Sciences of the United States of America. 90: 7240-4. PMID 7688473 DOI: 10.1073/Pnas.90.15.7240 |
0.345 |
|
| 1992 |
Salvemini D, Pistelli A, Mollace V, Änggård E, Vane J. The metabolism of glyceryl trinitrate to nitric oxide in the macrophage cell line J774 and its induction by Escherichia coli lipopolysaccharide Biochemical Pharmacology. 44: 17-24. PMID 1378739 DOI: 10.1016/0006-2952(92)90032-E |
0.511 |
|
| 1992 |
Salvemini D, Mollace V, Pistelli A, Anggard E, Vane J. Cultured astrocytoma cells generate a nitric oxide-like factor from endogenous L-arginine and glyceryl trinitrate: Effect of E. coli lipopolysaccharide British Journal of Pharmacology. 106: 931-936. PMID 1327394 DOI: 10.1111/J.1476-5381.1992.Tb14437.X |
0.503 |
|
| 1992 |
Gryglewski RJ, Zembowicz A, Salvemini D, Taylor GW, Vane JR. Modulation of the pharmacological actions of nitrovasodilators by methylene blue and pyocyanin British Journal of Pharmacology. 106: 838-845. PMID 1327388 DOI: 10.1111/J.1476-5381.1992.Tb14422.X |
0.511 |
|
| 1992 |
Salvemini D, Mollace V, Pistelli A, Anggard E, Vane J. Metabolism of glyceryl trinitrate to nitric oxide by endothelial cells and smooth muscle cells and its induction by Escherichia coli lipopolysaccharide Proceedings of the National Academy of Sciences of the United States of America. 89: 982-986. PMID 1310543 DOI: 10.1073/Pnas.89.3.982 |
0.512 |
|
| 1992 |
Salvemini D, Pistelli A, Mollace V, Anggard E, Vane J. J774 Cells metabolise glyceryl trinitrate by an enzymic pathway which can be induced by E. colt lipopolysaccharide Pharmacological Research. 26: 229. DOI: 10.1016/1043-6618(92)91167-F |
0.468 |
|
| 1991 |
Mollace V, Salvemini D, Vane J. Studies on the importance of the proposed release of nitric oxide from platelets Thrombosis Research. 65: 533-542. PMID 1725563 DOI: 10.1016/S0049-3848(05)80002-7 |
0.5 |
|
| 1991 |
Mollace V, Salvemini D, Anggard E, Vane J. Nitric oxide from vascular smooth muscle cells: Regulation of platelet reactivity and smooth muscle cell guanylate cyclase British Journal of Pharmacology. 104: 633-638. PMID 1724627 DOI: 10.1111/J.1476-5381.1991.Tb12481.X |
0.521 |
|
| 1991 |
Masini E, Salvemini D, Pistelli A, Mannaioni PF, Vane JR. Rat mast cells synthesize a nitric oxide like-factor which modulates the release of histamine Agents and Actions. 33: 61-63. PMID 1716838 DOI: 10.1007/Bf01993127 |
0.528 |
|
| 1991 |
Salvemini D, Radziszewski W, Mollace V, Moore A, Willoughby D, Vane J. Diphenylene iodonium, an inhibitor of free radical formation, inhibits platelet aggregation European Journal of Pharmacology. 199: 15-18. PMID 1716574 DOI: 10.1016/0014-2999(91)90631-Y |
0.489 |
|
| 1991 |
Masini E, Mannaioni PF, Pistelli A, Salvemini D, Vane J. Impairment of the L-arginine-nitric oxide pathway in mast cells from spontaneously hypertensive rats Biochemical and Biophysical Research Communications. 177: 1178-1182. PMID 1711845 DOI: 10.1016/0006-291X(91)90664-S |
0.525 |
|
| 1991 |
Mannaioni PF, Masini E, Pistelli A, Salvemini D, Viale JR. Rat mast cells inhibit platelet aggregation by releasing a nitric oxide-like factor: Influence of histamine release Agents and Actions. 33: 423-428. PMID 1711277 DOI: 10.1007/978-3-0348-7309-3_33 |
0.32 |
|
| 1991 |
Salvemini D, De Nucci G, Vane JR. Superoxide dismutase cooperates with prostacyclin to inhibit platelet aggregation: a comparative study in washed platelets and platelet rich plasma Thrombosis and Haemostasis. 65: 421-424. PMID 1647553 |
0.412 |
|
| 1991 |
Salvemini D, Masini E, Pistelli A, Mannaioni PF, Vane J. Nitric Oxide: A Regulatory Mediator of Mast Cell Reactivity Journal of Cardiovascular Pharmacology. 17. DOI: 10.1097/00005344-199100001-00046 |
0.521 |
|
| 1991 |
Salvemini D, Masini E, Pistelli A, Mannaioni PF, Vane J. Nitric oxide: A regulatory mediator of mast cell reactivity Journal of Cardiovascular Pharmacology. 17. |
0.481 |
|
| 1990 |
Mollace V, Salvemini D, Änggård E, Vane J. Cultured astrocytoma cells inhibit platelet aggregation by releasing a nitric oxide-like factor Biochemical and Biophysical Research Communications. 172: 564-569. PMID 2241954 DOI: 10.1016/0006-291X(90)90710-5 |
0.516 |
|
| 1990 |
Salvemini D, Korbut R, Änggård E, Vane J. Immediate release of a nitric oxide-like factor from bovine aortic endothelial cells by Escherichia coli lipopolysaccharide Proceedings of the National Academy of Sciences of the United States of America. 87: 2593-2597. PMID 2181441 DOI: 10.1073/Pnas.87.7.2593 |
0.523 |
|
| 1990 |
Salvemini D, Masini E, Anggard E, Mannaioni PF, Vane J. Synthesis of a nitric oxide-like factor from L-arginine by rat serosal mast cells: Stimulation of guanylate cyclase and inhibition of platelet aggregation Biochemical and Biophysical Research Communications. 169: 596-601. PMID 1972620 DOI: 10.1016/0006-291X(90)90372-T |
0.525 |
|
| 1990 |
Salvemini D, Radziszewski W, Korbut R, Vane J. The use of oxyhaemoglobin to explore the events underlying inhibition of platelet aggregation induced by NO or NO-donors British Journal of Pharmacology. 101: 991-995. PMID 1707709 DOI: 10.1111/J.1476-5381.1990.Tb14194.X |
0.505 |
|
| 1990 |
Mollace V, Salvemini D, Änggard E, Nisticò G, Vane J. Cultured astrocytoma cells release a nitric oxide-like factor Pharmacological Research. 22: 338. DOI: 10.1016/S1043-6618(09)80358-7 |
0.475 |
|
| 1990 |
Mannaioni PF, Masini E, Salvemini D, Pistelli A, Korbut R, Vane JR. Mast cell derived relaxing factor and the effect of nitric oxide generators on mast cell histamine release European Journal of Pharmacology. 183: 711. DOI: 10.1016/0014-2999(90)92505-D |
0.489 |
|
| 1989 |
Salvemini D, De Nucci G, Sneddon JM, Vane JR. Superoxide anions enhance platelet adhesion and aggregation British Journal of Pharmacology. 97: 1145-1150. PMID 2551440 DOI: 10.1111/J.1476-5381.1989.Tb12572.X |
0.477 |
|
| 1989 |
Salvemini D, De Nucci G, Gryglewski RJ, Vane JR. Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor Proceedings of the National Academy of Sciences of the United States of America. 86: 6328-6332. PMID 2548208 DOI: 10.1073/Pnas.86.16.6328 |
0.517 |
|
| 1989 |
Salvemini D, Korbut R, Änggård E, Vane JR. Lipopolysaccharide increases release of a nitric oxide-like factor from endothelial cells European Journal of Pharmacology. 171: 135-136. PMID 2515068 DOI: 10.1016/0014-2999(89)90437-8 |
0.447 |
|
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