Gao Zhang, Ph.D. - Related publications

Affiliations: 
2012 Bioengineering University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biomedical Engineering, Oncology, Cell Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Qin S, Jiang J, Lu Y, Nice EC, Huang C, Zhang J, He W. Emerging role of tumor cell plasticity in modifying therapeutic response. Signal Transduction and Targeted Therapy. 5: 228. PMID 33028808 DOI: 10.1038/s41392-020-00313-5   
2020 Hager S, Fittler FJ, Wagner E, Bros M. Nucleic Acid-Based Approaches for Tumor Therapy. Cells. 9. PMID 32917034 DOI: 10.3390/cells9092061   
2020 Zhuang X, Maione F, Robinson J, Bentley M, Kaul B, Whitworth K, Jumbu N, Jinks E, Bystrom J, Gabriele P, Garibaldi E, Delmastro E, Nagy Z, Gilham D, Giraudo E, et al. CAR T cells targeting tumor endothelial marker CLEC14A inhibit tumor growth. Jci Insight. 5. PMID 33004686 DOI: 10.1172/jci.insight.138808   
2020 Zhuang X, Maione F, Robinson J, Bentley M, Kaul B, Whitworth K, Jumbu N, Jinks E, Bystrom J, Gabriele P, Garibaldi E, Delmastro E, Nagy Z, Gilham D, Giraudo E, et al. CAR T cells targeting tumor endothelial marker CLEC14A inhibit tumor growth. Jci Insight. 5. PMID 33004686 DOI: 10.1172/jci.insight.138808   
2020 Metz EP, Wuebben EL, Wilder PJ, Cox JL, Datta K, Coulter D, Rizzino A. Tumor quiescence: elevating SOX2 in diverse tumor cell types downregulates a broad spectrum of the cell cycle machinery and inhibits tumor growth. Bmc Cancer. 20: 941. PMID 32998722 DOI: 10.1186/s12885-020-07370-7   
2020 Ward AB, Keeton AB, Chen X, Mattox TE, Coley AB, Maxuitenko YY, Buchsbaum DJ, Randall TD, Zhou G, Piazza GA. Enhancing anticancer activity of checkpoint immunotherapy by targeting RAS. Medcomm. 1: 121-128. PMID 33073260 DOI: 10.1002/mco2.10   
2020 Espinosa-Sánchez A, Suárez-Martínez E, Sánchez-Díaz L, Carnero A. Therapeutic Targeting of Signaling Pathways Related to Cancer Stemness. Frontiers in Oncology. 10: 1533. PMID 32984007 DOI: 10.3389/fonc.2020.01533   
2020 Guan Y, Lin M, Yin J, Zhuang Y, Wang Y. [Progress on the role of integrin in tumor immunity: Review]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 36: 750-754. PMID 32958132   
2020 Wolf-Dennen K, Kleinerman ES. Exosomes: Dynamic Mediators of Extracellular Communication in the Tumor Microenvironment. Advances in Experimental Medicine and Biology. 1258: 189-197. PMID 32767243 DOI: 10.1007/978-3-030-43085-6_13   
2020 Zhang J. Targeting mTOR by CZ415 Suppresses Cell Proliferation and Promotes Apoptosis via Lipin-1 in Cervical Cancer In Vitro and In Vivo. Reproductive Sciences (Thousand Oaks, Calif.). PMID 32944878 DOI: 10.1007/s43032-020-00313-4   
2020 Chen Z, Zhou L, Liu L, Hou Y, Xiong M, Yang Y, Hu J, Chen K. Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma. Nature Communications. 11: 5077. PMID 33033240 DOI: 10.1038/s41467-020-18916-5   
2020 Richard V, Kumar TRS, Pillai RM. Transitional dynamics of cancer stem cells in invasion and metastasis. Translational Oncology. 14: 100909. PMID 33049522 DOI: 10.1016/j.tranon.2020.100909   
2020 Bandari SK, Tripathi K, Rangarajan S, Sanderson RD. Therapy-induced chemoexosomes: Sinister small extracellular vesicles that support tumor survival and progression. Cancer Letters. PMID 32858103 DOI: 10.1016/j.canlet.2020.08.022   
2020 Areeb Z, Stuart SF, West AJ, Gomez J, Nguyen HPT, Paradiso L, Zulkifli A, Jones J, Kaye AH, Morokoff AP, Luwor RB. Reduced EGFR and increased miR-221 is associated with increased resistance to temozolomide and radiotherapy in glioblastoma. Scientific Reports. 10: 17768. PMID 33082482 DOI: 10.1038/s41598-020-74746-x   
2020 Costa MS, Gonçalves YG, Borges BC, Silva MJB, Amstalden MK, Costa TR, Antunes LMG, Rodrigues RS, Rodrigues VM, de Faria Franca E, Zoia MAP, de Araújo TG, Goulart LR, Von Poelhsitz G, Yoneyama KAG. Ruthenium (II) complex cis-[Ru(ŋ-OCCHO)(dppm)]PF-hmxbato induces ROS-mediated apoptosis in lung tumor cells producing selective cytotoxicity. Scientific Reports. 10: 15410. PMID 32958783 DOI: 10.1038/s41598-020-72420-w   
2020 Zhang LN, Zhang DD, Yang L, Gu YX, Zuo QP, Wang HY, Xu J, Liu DX. Roles of cell fusion between mesenchymal stromal/stem cells and malignant cells in tumor growth and metastasis. The Febs Journal. PMID 33070450 DOI: 10.1111/febs.15483   
2020 Chang TC, Matossian MD, Elliott S, Burks HE, Sabol RA, Ucar DA, Wathieu H, Zabaleta J, Valle L, Gill S, Martin E, Riker AI, Miele L, Bunnell BA, Burow ME, et al. Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor. Plos One. 15: e0226464. PMID 33035223 DOI: 10.1371/journal.pone.0226464   
2020 Wang F, Luo R, Xin H, Zhang Y, Córdova Wong BJ, Wang W, Lei J. Hypoxia-stimulated tumor therapy associated with the inhibition of cancer cell stemness. Biomaterials. 263: 120330. PMID 32942127 DOI: 10.1016/j.biomaterials.2020.120330   
2020 Ernst A, Hennel R, Krombach J, Kapfhammer H, Brix N, Zuchtriegel G, Uhl B, Reichel CA, Frey B, Gaipl US, Winssinger N, Shirasawa S, Sasazuki T, Sperandio M, Belka C, et al. Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90. Frontiers in Oncology. 10: 1668. PMID 32984042 DOI: 10.3389/fonc.2020.01668   
2020 Wang Y, Zhang JJ, Huang XY. Anti-Metastasis Fascin Inhibitors Decrease the Growth of Specific Subtypes of Cancers. Cancers. 12. PMID 32824026 DOI: 10.3390/cancers12082287   
2020 Wu F, Fan J, Fang J, Dalvi PS, Odenthal M, Fang N. Single Cell Sequencing: A New Dimension in Cancer Diagnosis and Treatment. Advances in Experimental Medicine and Biology. 1255: 109-121. PMID 32949394 DOI: 10.1007/978-981-15-4494-1_9   
2020 Tan Y, Lu X, Cheng Z, Pan G, Liu S, Apiziaji P, Wang H, Zhang J, Abulimiti Y. miR-148a Regulates the Stem Cell-Like Side Populations Distribution by Affecting the Expression of ACVR1 in Esophageal Squamous Cell Carcinoma. Oncotargets and Therapy. 13: 8079-8094. PMID 32904700 DOI: 10.2147/OTT.S248925   
2020 Le X, Mu J, Peng W, Tang J, Xiang Q, Tian S, Feng Y, He S, Qiu Z, Ren G, Huang A, Lin Y, Tao Q, Xiang T. DNA methylation downregulated ZDHHC1 suppresses tumor growth by altering cellular metabolism and inducing oxidative/ER stress-mediated apoptosis and pyroptosis. Theranostics. 10: 9495-9511. PMID 32863941 DOI: 10.7150/thno.45631   
2020 Pang W, Li Y, Guo W, Shen H. Cyclin E: a potential treatment target to reverse cancer chemoresistance by regulating the cell cycle. American Journal of Translational Research. 12: 5170-5187. PMID 33042412   
2020 Hong S, Bi M, Yu H, Yan Z, Wang H. Radiation therapy enhanced therapeutic efficacy of anti-PD1 against gastric cancer. Journal of Radiation Research. PMID 32960261 DOI: 10.1093/jrr/rraa077   
2020 Lu YB, Sun TJ, Chen YT, Cai ZY, Zhao JY, Miao F, Yang YN, Wang SX. Targeting the Epithelial-to-Mesenchymal Transition in Cancer Stem Cells for a Better Clinical Outcome of Glioma. Technology in Cancer Research & Treatment. 19: 1533033820948053. PMID 33089751 DOI: 10.1177/1533033820948053   
2020 Brock RM, Beitel-White N, Davalos RV, Allen IC. Starting a Fire Without Flame: The Induction of Cell Death and Inflammation in Electroporation-Based Tumor Ablation Strategies. Frontiers in Oncology. 10: 1235. PMID 32850371 DOI: 10.3389/fonc.2020.01235   
2020 Smalley M, Natarajan SK, Mondal J, Goldman D, Shanthappa B, Pellowe M, Dash C, Saha T, Khiste S, Ramadurai N, Eton EO, Smalley JL, Brown A, Thayakumar A, Rahman M, et al. Nano-Engineered Disruption of Heat shock protein 90 (Hsp90) Targets Drug-Induced Resistance and Relieves Natural Killer Cell Suppression in Breast Cancer. Cancer Research. PMID 33077554 DOI: 10.1158/0008-5472.CAN-19-4036   
2020 Meršaková S, Lasabová Z, Strnádel J, Kalman M, Gabonova E, Sabaka P, Ciccocioppo R, Rodrigo L, Kruzliak P, Mikolajčík P. Genomic profile and immune contexture in colorectal cancer-relevance for prognosis and immunotherapy. Clinical and Experimental Medicine. PMID 32720224 DOI: 10.1007/s10238-020-00649-w   
2020 Gestermann N, Saugy D, Martignier C, Tillé L, Fuertes Marraco SA, Zettl M, Tirapu I, Speiser DE, Verdeil G. LAG-3 and PD-1+LAG-3 inhibition promote anti-tumor immune responses in human autologous melanoma/T cell co-cultures. Oncoimmunology. 9: 1736792. PMID 32850194 DOI: 10.1080/2162402X.2020.1736792   
2020 Wen W, Han ES, Dellinger TH, Lu LX, Wu J, Jove R, Yim JH. Synergistic Anti-Tumor Activity by Targeting Multiple Signaling Pathways in Ovarian Cancer. Cancers. 12. PMID 32927828 DOI: 10.3390/cancers12092586   
2020 Klampatsa A, Albelda SM. Current Advances in CAR T Cell Therapy for Malignant Mesothelioma. Journal of Cellular Immunology. 2: 192-200. PMID 32914147 DOI: 10.33696/immunology.2.042   
2020 Lee WS, Yang H, Chon HJ, Kim C. Combination of anti-angiogenic therapy and immune checkpoint blockade normalizes vascular-immune crosstalk to potentiate cancer immunity. Experimental & Molecular Medicine. PMID 32913278 DOI: 10.1038/s12276-020-00500-y   
2020 Lei X, Ma N, Du L, Liang Y, Zhang P, Han Y, Qu B. PP2A and tumor radiotherapy. Hereditas. 157: 36. PMID 32847617 DOI: 10.1186/s41065-020-00149-7   
2020 Xiong W, Liao Y, Qin JY, Li WH, Tang ZY. Adverse effects of chemoradiotherapy on invasion and metastasis of tumor cells. Genes & Diseases. 7: 351-358. PMID 32884989 DOI: 10.1016/j.gendis.2020.04.004   
2020 Sanz-Ortega L, Rojas JM, Barber DF. Improving Tumor Retention of Effector Cells in Adoptive Cell Transfer Therapies by Magnetic Targeting. Pharmaceutics. 12. PMID 32867162 DOI: 10.3390/pharmaceutics12090812   
2020 Si W, Zhou B, Xie W, Li H, Li K, Li S, Deng W, Shi P, Yuan C, Ke T, Ren X, Tu X, Zeng X, Weigelt B, Rubin BP, et al. Angiogenic factor AGGF1 acts as a tumor suppressor by modulating p53 post-transcriptional modifications and stability via MDM2. Cancer Letters. PMID 33069768 DOI: 10.1016/j.canlet.2020.10.014   
2020 Corso CR, Stipp MC, Radulski DR, Mariott M, da Silva LM, de Souza Ramos EA, Klassen G, Queiroz Telles JE, Oliveira CS, Stefanello MÉA, Verhoeven AJ, Oude Elferink RPJ, Acco A. Fruticuline A, a chemically-defined diterpene, exerts antineoplastic effects in vitro and in vivo by multiple mechanisms. Scientific Reports. 10: 16477. PMID 33020521 DOI: 10.1038/s41598-020-73432-2   
2020 Lombardo ME, Zito G, Pavia FC, Pizzolanti G, Giordano C, Brucato V, La Carrubba V. 3D polymeric supports promote the growth and progression of anaplastic thyroid carcinoma. Biochemical and Biophysical Research Communications. 531: 223-227. PMID 32798016 DOI: 10.1016/j.bbrc.2020.07.062   
2020 Dhodapkar MV, Dhodapkar KM. Tissue-resident memory-like T cells in tumor immunity: Clinical implications. Seminars in Immunology. 101415. PMID 33011063 DOI: 10.1016/j.smim.2020.101415   
2020 Lee Y, Park SH, Lee JH, Ryu HW, Jang HJ, Kim WJ, Hwang E, Kim SJ, Jun HS, Ha UH. The Anti-Tumor Effects of Extract Are Mediated by Inhibition of Glycolysis and Cellular Respiration in Cancer Cells. Nutrition and Cancer. 1-11. PMID 32964733 DOI: 10.1080/01635581.2020.1824000   
2020 Arkhypov I, Lasser S, Petrova V, Weber R, Groth C, Utikal J, Altevogt P, Umansky V. Myeloid Cell Modulation by Tumor-Derived Extracellular Vesicles. International Journal of Molecular Sciences. 21. PMID 32878277 DOI: 10.3390/ijms21176319   
2020 Huang X, Cai W, Liu L, Yuan W. Low mutation burden and differential tumor-infiltrating immune cells correlate with lymph node metastasis in colorectal cancer. International Journal of Clinical and Experimental Pathology. 13: 2259-2269. PMID 33042330   
2020 Zhang H, Wang Y, Liu X, Li Y. Progress of long noncoding RNAs in anti-tumor resistance. Pathology, Research and Practice. 216: 153215. PMID 32979688 DOI: 10.1016/j.prp.2020.153215   
2020 Chang S, Huang J, Niu H, Wang J, Si Y, Bai Z, Cheng S, Ding W. Epigenetic regulation of osteopontin splicing isoform c defines its role as a microenvironmental factor to promote the survival of colon cancer cells from 5-FU treatment. Cancer Cell International. 20: 452. PMID 32944000 DOI: 10.1186/s12935-020-01541-z   
2020 Suresh D, Ghoshdastidar S, Gangula A, Mukherjee S, Upendran A, Kannan R. Magnetic Iron Nanocubes Effectively Capture Epithelial and Mesenchymal Cancer Cells. Acs Omega. 5: 23724-23735. PMID 32984691 DOI: 10.1021/acsomega.0c02699   
2020 Lee HJ, Kim KJ, Sung JH, Nam M, Suh KJ, Kim JW, Kim SH, Kim JW, Kim YJ, Lee KW, Lee JS, Kim JH. PI3K p110α Blockade Enhances Anti-Tumor Efficacy of Abemaciclib in Human Colorectal Cancer Cells. Cancers. 12. PMID 32899250 DOI: 10.3390/cancers12092500   
2020 Kikuchi M, Yamashita D, Hara S, Takebayashi S, Hamaguchi K, Mizuno K, Omori K, Shinohara S. Clinical significance of tumor-associated immune cells in patients with oral squamous cell carcinoma. Head & Neck. PMID 33029887 DOI: 10.1002/hed.26498   
2020 Macașoi I, Pavel IZ, Moacă AE, Avram Ș, David VL, Coricovac D, Mioc A, Spandidos DA, Tsatsakis A, Șoica C, Dumitrașcu V, Dehelean C. Mechanistic investigations of antitumor activity of a Rhodamine B‑oleanolic acid derivative bioconjugate. Oncology Reports. 44: 1169-1183. PMID 32705265 DOI: 10.3892/or.2020.7666   
2020 Wang B, Sun L, Zhao J, An J, Jin Y, Yang X, Li H, Zhang H, Zhang Z, Youmei A. Limiting tumor cells comprehensively at micro and macro levels to improve the therapeutic effect of chemotherapy. Nanotechnology. 32: 015301. PMID 33078716 DOI: 10.1088/1361-6528/abb48f