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Nilsson Holguin, Ph.D. - Publications

Affiliations: 
2010 Biomedical Engineering Stony Brook University, Stony Brook, NY, United States 
Area:
Biomedical Engineering, Biomechanics Biophysics, Aerospace Engineering
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22/28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Silva MJ, Holguin N. Aging aggravates intervertebral disc degeneration by regulating transcription factors toward chondrogenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 31909538 DOI: 10.1096/Fj.201902109R  0.535
2018 Holguin N, Silva MJ. In-Vivo Nucleus Pulposus-Specific Regulation of Adult Murine Intervertebral Disc Degeneration via Wnt/Beta-Catenin Signaling. Scientific Reports. 8: 11191. PMID 30046041 DOI: 10.1038/S41598-018-29352-3  0.526
2017 Sun D, Brodt MD, Zannit HM, Holguin N, Silva MJ. Evaluation of loading parameters for murine axial tibial loading: Stimulating cortical bone formation while reducing loading duration. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28888055 DOI: 10.1002/Jor.23727  0.597
2017 Duan X, Sandell LJ, Chinzei N, Holguin N, Silva MJ, Schiavinato A, Rai MF. Therapeutic efficacy of intra-articular hyaluronan derivative and platelet-rich plasma in mice following axial tibial loading. Plos One. 12: e0175682. PMID 28406954 DOI: 10.1371/Journal.Pone.0175682  0.525
2017 Rai MF, Duan X, Quirk JD, Holguin N, Schmidt EJ, Chinzei N, Silva MJ, Sandell LJ. Post-Traumatic Osteoarthritis in Mice Following Mechanical Injury to the Synovial Joint. Scientific Reports. 7: 45223. PMID 28345597 DOI: 10.1038/Srep45223  0.578
2016 Yan H, Duan X, Pan H, Holguin N, Rai MF, Akk A, Springer LE, Wickline SA, Sandell LJ, Pham CT. Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 27681622 DOI: 10.1073/Pnas.1608245113  0.311
2016 Xin D, Farooq Rai M, Holguin N, Silva MJ, Patra D, Liao W, Sandell LJ. Early changes in the knee of healer and non-healer mice following non-invasive mechanical injury. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 27591401 DOI: 10.1002/Jor.23413  0.567
2016 Holguin N, Brodt MD, Silva MJ. Activation of Wnt Signaling By Mechanical Loading Is Impaired in the Bone of Old Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27357062 DOI: 10.1002/Jbmr.2900  0.595
2015 Chen J, Holguin N, Shi Y, Silva MJ, Long F. mTORC2 signaling promotes skeletal growth and bone formation in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 369-78. PMID 25196701 DOI: 10.1002/Jbmr.2348  0.577
2015 Rai M, Duan X, Holguin N, Quirk J, Silva M, Sandell L. Early response to impact knee injury in genetic strains of mice reveals similarity in cartilage but differences in synovium Osteoarthritis and Cartilage. 23: A193. DOI: 10.1016/J.Joca.2015.02.979  0.528
2014 Holguin N, Brodt MD, Sanchez ME, Silva MJ. Aging diminishes lamellar and woven bone formation induced by tibial compression in adult C57BL/6. Bone. 65: 83-91. PMID 24836737 DOI: 10.1016/J.Bone.2014.05.006  0.595
2014 Holguin N, Aguilar R, Harland RA, Bomar BA, Silva MJ. The aging mouse partially models the aging human spine: lumbar and coccygeal disc height, composition, mechanical properties, and Wnt signaling in young and old mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 116: 1551-60. PMID 24790018 DOI: 10.1152/Japplphysiol.01322.2013  0.571
2014 Wu P, Holguin N, Silva MJ, Fu M, Liao W, Sandell LJ. Early response of mouse joint tissue to noninvasive knee injury suggests treatment targets Arthritis and Rheumatology. 66: 1256-1265. PMID 24470303 DOI: 10.1002/Art.38375  0.574
2013 Holguin N, Brodt MD, Sanchez ME, Kotiya AA, Silva MJ. Adaptation of tibial structure and strength to axial compression depends on loading history in both C57BL/6 and BALB/c mice. Calcified Tissue International. 93: 211-21. PMID 23708853 DOI: 10.1007/S00223-013-9744-4  0.598
2013 Holguin N, Martin JT, Elliott DM, Judex S. Low-intensity vibrations partially maintain intervertebral disc mechanics and spinal muscle area during deconditioning. The Spine Journal : Official Journal of the North American Spine Society. 13: 428-36. PMID 23507530 DOI: 10.1016/J.Spinee.2013.01.046  0.619
2013 Wu P, Holguin N, Silva M, Liao W, Sandell L. Early responses of joint tissues to noninvasive mouse knee injury provide potential targets for therapy Osteoarthritis and Cartilage. 21: S64-S65. DOI: 10.1016/J.Joca.2013.02.143  0.517
2011 Holguin N, Uzer G, Chiang FP, Rubin C, Judex S. Brief daily exposure to low-intensity vibration mitigates the degradation of the intervertebral disc in a frequency-specific manner. Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 1846-53. PMID 21960658 DOI: 10.1152/Japplphysiol.00846.2011  0.706
2010 Holguin N, Judex S. Rat intervertebral disc health during hindlimb unloading: brief ambulation with or without vibration. Aviation, Space, and Environmental Medicine. 81: 1078-84. PMID 21197851 DOI: 10.3357/Asem.2818.2010  0.616
2010 Holguin N, Muir J, Rubin C, Judex S. Reply Spine Journal. 10: 364-365. DOI: 10.1016/j.spinee.2010.02.012  0.447
2009 Holguin N, Muir J, Rubin C, Judex S. Short applications of very low-magnitude vibrations attenuate expansion of the intervertebral disc during extended bed rest. The Spine Journal : Official Journal of the North American Spine Society. 9: 470-7. PMID 19356986 DOI: 10.1016/J.Spinee.2009.02.009  0.712
2007 Holguin N, Muir J, Evans HJ, Qin YX, Rubin C, Wagshul M, Judex S. Mechanical vibrations reduce the intervertebral disc swelling and muscle atrophy from bed rest Bioengineering, Proceedings of the Northeast Conference. 25-26. DOI: 10.1109/NEBC.2007.4413262  0.708
2007 Muir J, Xia Y, Holguin N, Judex S, Qin YX, Jeka J, Evans H, Lang T, Rubin C. Retention of bone density and postural status with a non-invasive extremely low level mechanical signal: A ground based evaluation of efficacy Bioengineering, Proceedings of the Northeast Conference. 1-2. DOI: 10.1109/NEBC.2007.4413250  0.697
Low-probability matches (unlikely to be authored by this person)
2022 Kroon T, Bhadouria N, Niziolek P, Edwards D, Choi R, Clinkenbeard EL, Robling A, Holguin N. Suppression of Sost/Sclerostin and Dickkopf-1 Augment Intervertebral Disc Structure in Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 35278242 DOI: 10.1002/jbmr.4546  0.264
2023 Wang D, Lai A, Gansau J, Seifert AC, Munitz J, Zaheer K, Bhadouria N, Lee Y, Nasser P, Laudier DM, Holguin N, Hecht AC, Iatridis JC. Lumbar endplate microfracture injury induces Modic-like changes, intervertebral disc degeneration and spinal cord sensitization - An In Vivo Rat Model. Biorxiv : the Preprint Server For Biology. PMID 36778423 DOI: 10.1101/2023.01.27.525924  0.212
2016 Holguin N. CORR Insights(®): The NLRP3/Caspase-1/Interleukin-1β Axis Is Active in Human Lumbar Cartilaginous Endplate Degeneration. Clinical Orthopaedics and Related Research. PMID 27245769 DOI: 10.1007/S11999-016-4912-2  0.209
2022 Bhadouria N, Berman AG, Wallace JM, Holguin N. Raloxifene Stimulates Estrogen Signaling to Protect Against Age- and Sex-Related Intervertebral Disc Degeneration in Mice. Frontiers in Bioengineering and Biotechnology. 10: 924918. PMID 36032728 DOI: 10.3389/fbioe.2022.924918  0.207
2016 Holguin N. CORR Insights(®): Does Sclerostin Depletion Stimulate Fracture Healing in a Mouse Model? Clinical Orthopaedics and Related Research. PMID 26758443 DOI: 10.1007/S11999-016-4697-3  0.199
2023 Wang D, Lai A, Gansau J, Seifert AC, Munitz J, Zaheer K, Bhadouria N, Lee Y, Nasser P, Laudier DM, Holguin N, Hecht AC, Iatridis JC. Lumbar endplate microfracture injury induces Modic-like changes, intervertebral disc degeneration and spinal cord sensitization - An In Vivo Rat Model. The Spine Journal : Official Journal of the North American Spine Society. PMID 37086976 DOI: 10.1016/j.spinee.2023.04.012  0.164
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