Karl J. Jepsen - Publications

Affiliations: 
Engineering City University of New York, New York, NY, United States 
Area:
Biomedical Engineering, Biomechanics Biophysics

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Jepsen KJ, Bigelow EMR, Goulet RW, Nolan BT, Casden MA, Kennedy K, Hertz S, Kadur C, Clines GA, Leis AM, Karvonen-Gutierrez CA, Bredbenner TL. Structural differences contributing to sex-specific associations between FN BMD and whole-bone strength for adult White women and men. Jbmr Plus. 8: ziae013. PMID 38523663 DOI: 10.1093/jbmrpl/ziae013  0.376
2023 Loundagin LL, Bredbenner TL, Jepsen KJ, Edwards WB. Correction: Bringing Mechanical Context to Image-Based Measurements of Bone Integrity. Current Osteoporosis Reports. PMID 37837513 DOI: 10.1007/s11914-023-00829-z  0.392
2023 Whitney DG, Caird MS, Raggio CL, Hurvitz EA, Clines GA, Jepsen KJ. Perspective: A multi-trait integrative approach to understanding the structural basis of bone fragility for pediatric conditions associated with abnormal bone development. Bone. 175: 116855. PMID 37481149 DOI: 10.1016/j.bone.2023.116855  0.542
2023 Jepsen KJ, Bigelow EM, Casden MA, Goulet RW, Kennedy K, Hertz S, Kadur C, Nolan BT, Richards-McCullough K, Merillat S, Karvonen-Gutierrez CA, Clines G, Bredbenner TL. Associations Among Hip Structure, Bone Mineral Density, and Strength Vary With External Bone Size in White Women. Jbmr Plus. 7: e10715. PMID 36936363 DOI: 10.1002/jbm4.10715  0.524
2022 Bigelow EMR, Goulet RW, Ciarelli A, Schlecht SH, Kohn DH, Bredbenner TL, Harlow SD, Karvonen-Gutierrez CA, Jepsen KJ. Sex and External Size Specific Limitations in Assessing Bone Health From Adult Hand Radiographs. Jbmr Plus. 6: e10653. PMID 35991534 DOI: 10.1002/jbm4.10653  0.439
2022 Bolger MW, Romanowicz GE, Bigelow EMR, Ward FS, Ciarelli A, Jepsen KJ, Kohn DH. Divergent mechanical properties of older male femora identified by latent profile analysis reveal morphological and compositional traits contributing uniquely to low strength. Bone. 116481. PMID 35817317 DOI: 10.1016/j.bone.2022.116481  0.375
2022 Mandair GS, Bigelow EMR, Viswanathan G, Ward FS, Patton DM, Schlecht SH, Jepsen KJ, Kohn DH. Region-specific associations among tissue-level mechanical properties, porosity, and composition in human male femora. Journal of Biomechanics. 139: 111144. PMID 35623287 DOI: 10.1016/j.jbiomech.2022.111144  0.484
2021 Whitney DG, Caird MS, Clines GA, Hurvitz EA, Jepsen KJ. Clinical bone health among adults with cerebral palsy: moving beyond assessing bone mineral density alone. Developmental Medicine and Child Neurology. PMID 34658010 DOI: 10.1111/dmcn.15093  0.5
2021 Shanas N, Querido W, Oswald J, Jepsen K, Carter E, Raggio C, Pleshko N. Infrared Spectroscopy-Determined Bone Compositional Changes Associated with Anti-Resorptive Treatment of the Mouse Model of Osteogenesis Imperfecta. Applied Spectroscopy. 37028211055477. PMID 34643134 DOI: 10.1177/00037028211055477  0.491
2021 Loundagain LL, Bredbenner TL, Jepsen KJ, Edwards WB. Bringing Mechanical Context to Image-Based Measurements of Bone Integrity. Current Osteoporosis Reports. PMID 34269975 DOI: 10.1007/s11914-021-00700-z  0.5
2021 Patton DM, Ochocki DN, Martin CT, Casden M, Jepsen KJ, Ashton-Miller JA, Wojtys EM, Schlecht SH. State of the mineralized tissue comprising the femoral ACL enthesis in young women with an ACL failure. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 34191360 DOI: 10.1002/jor.25130  0.402
2021 Patton DM, Ochocki DN, Martin CT, Casden M, Jepsen KJ, Ashton-Miller JA, Wojtys EM, Schlecht SH. State of the mineralized tissue comprising the femoral ACL enthesis in young women with an ACL failure. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 34191360 DOI: 10.1002/jor.25130  0.402
2021 Whitney DG, Kalia V, Rajapakse CS, Fedak Romanowski EM, Caird MS, Hurvitz EA, Jepsen KJ. The effect of age when initiating anti-seizure medication therapy on fragility fracture risk for children with epilepsy. Bone. 149: 115996. PMID 33962082 DOI: 10.1016/j.bone.2021.115996  0.327
2020 Bolger MW, Romanowicz GE, Bigelow EMR, Ward FS, Ciarelli A, Jepsen KJ, Kohn DH. External bone size identifies different strength-decline trajectories for the male human femora. Journal of Structural Biology. 107650. PMID 33096230 DOI: 10.1016/j.jsb.2020.107650  0.444
2020 Zhang H, Zhang Y, Terajima M, Romanowicz G, Liu Y, Omi M, Bigelow E, Joiner DM, Waldorff EI, Zhu P, Raghavan M, Lynch M, Kamiya N, Zhang R, Jepsen KJ, et al. Loss of BMP signaling mediated by BMPR1A in osteoblasts leads to differential bone phenotypes in mice depending on anatomical location of the bones. Bone. 115402. PMID 32360900 DOI: 10.1016/J.Bone.2020.115402  0.622
2019 Mathis NJ, Adaniya EN, Smith LM, Robling AG, Jepsen KJ, Schlecht SH. Differential changes in bone strength of two inbred mouse strains following administration of a sclerostin-neutralizing antibody during growth. Plos One. 14: e0214520. PMID 30947279 DOI: 10.1371/Journal.Pone.0214520  0.541
2019 Shidara K, Mohan G, Evan Lay YA, Jepsen KJ, Yao W, Lane NE. Strain-specific differences in the development of bone loss and incidence of osteonecrosis following glucocorticoid treatment in two different mouse strains. Journal of Orthopaedic Translation. 16: 91-101. PMID 30723686 DOI: 10.1016/J.Jot.2018.07.001  0.45
2019 Bigelow EM, Patton DM, Ward FS, Ciarelli A, Casden M, Clark A, Goulet RW, Morris MD, Schlecht SH, Mandair GS, Bredbenner TL, Kohn DH, Jepsen KJ. External Bone Size Is a Key Determinant of Strength-Decline Trajectories of Aging Male Radii. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. e3661. PMID 30715752 DOI: 10.1002/Jbmr.3661  0.469
2019 Citron K, Yonko E, Khan S, Carter E, Jepsen K, Raggio C. Bone morphology patterns in children with osteogenesis imperfecta Bone Abstracts. DOI: 10.1530/Boneabs.7.P7  0.474
2018 Patton DM, Bigelow EMR, Schlecht SH, Kohn DH, Bredbenner TL, Jepsen KJ. The relationship between whole bone stiffness and strength is age and sex dependent. Journal of Biomechanics. PMID 30527634 DOI: 10.1016/J.Jbiomech.2018.11.030  0.416
2018 Schlecht SH, Ramcharan MA, Yang Y, Smith LM, Bigelow EM, Nolan BT, Moss DE, Devlin MJ, Jepsen KJ. Differential Adaptive Response of Growing Bones From Two Female Inbred Mouse Strains to Voluntary Cage-Wheel Running. Jbmr Plus. 2: 143-153. PMID 30283899 DOI: 10.1002/jbm4.10032  0.794
2018 Xin F, Smith LM, Susiarjo M, Bartolomei MS, Jepsen KJ. Endocrine-disrupting chemicals, epigenetics, and skeletal system dysfunction: exploration of links using bisphenol A as a model system. Environmental Epigenetics. 4: dvy002. PMID 29732168 DOI: 10.1093/Eep/Dvy002  0.492
2017 Ebrahim FH, Ruellas ACO, Paniagua B, Benavides E, Jepsen K, Wolford L, Goncalves JR, Cevidanes LHS. Accuracy of biomarkers obtained from cone beam computed tomography in assessing the internal trabecular structure of the mandibular condyle. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. PMID 29055644 DOI: 10.1016/J.Oooo.2017.08.013  0.441
2017 Citron K, Veneziale C, Marino J, Carter EM, Jepsen KJ, Raggio C. Bone robusticity in two distinct skeletal dysplasias diverges from established patterns. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28186356 DOI: 10.1002/Jor.23543  0.544
2017 Schlecht SH, Smith LM, Ramcharan MA, Bigelow EM, Nolan BT, Mathis NJ, Cathey A, Manley E, Menon R, McEachin RC, Nadeau JH, Jepsen KJ. Canalization leads to similar whole bone mechanical function at maturity in two inbred strains of mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28177139 DOI: 10.1002/Jbmr.3093  0.814
2017 Jepsen KJ, Kozminski A, Bigelow EM, Schlecht SH, Goulet RW, Harlow SD, Cauley JA, Karvonen-Gutierrez C. Femoral Neck External Size but not aBMD Predicts Structural and Mass Changes for Women Transitioning through Menopause. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28084657 DOI: 10.1002/Jbmr.3082  0.575
2016 Gehlot P, Volk SL, Rios HF, Jepsen KJ, Holoshitz J. Spontaneous destructive periodontitis and skeletal bone damage in transgenic mice carrying a human shared epitope-coding HLA-DRB1 allele. Rmd Open. 2: e000349. PMID 27933212 DOI: 10.1136/Rmdopen-2016-000349  0.487
2016 Scheller EL, Doucette CR, Learman BS, Cawthorn WP, Khandaker S, Schell B, Wu B, Ding SY, Bredella MA, Fazeli PK, Khoury B, Jepsen KJ, Pilch PF, Klibanski A, Rosen CJ, et al. Corrigendum: Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues. Nature Communications. 7: 13775. PMID 27929114 DOI: 10.1038/Ncomms13775  0.347
2016 Ramcharan MA, Faillace ME, Guengerich Z, Williams VA, Jepsen KJ. The development of inter-strain variation in cortical and trabecular traits during growth of the mouse lumbar vertebral body. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. PMID 27734101 DOI: 10.1007/S00198-016-3801-6  0.79
2016 Jepsen KJ, Bigelow EM, Ramcharan M, Schlecht SH, Karvonen-Gutierrez CA. Moving toward a prevention strategy for osteoporosis by giving a voice to a silent disease. Women's Midlife Health. 2. PMID 27672442 DOI: 10.1186/S40695-016-0016-0  0.812
2016 Aref MW, McNerny EM, Brown D, Jepsen KJ, Allen MR. Zoledronate treatment has different effects in mouse strains with contrasting baseline bone mechanical phenotypes. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. PMID 27439372 DOI: 10.1007/S00198-016-3701-9  0.525
2016 Aslam MN, Jepsen KJ, Khoury B, Graf KH, Varani J. Bone structure and function in male C57BL/6 mice: Effects of a high-fat Western-style diet with or without trace minerals. Bone Reports. 5: 141-149. PMID 27350956 DOI: 10.1016/J.Bonr.2016.05.002  0.427
2015 Scheller EL, Doucette CR, Learman BS, Cawthorn WP, Khandaker S, Schell B, Wu B, Ding SY, Bredella MA, Fazeli PK, Khoury B, Jepsen KJ, Pilch PF, Klibanski A, Rosen CJ, et al. Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues. Nature Communications. 6: 7808. PMID 26245716 DOI: 10.1038/Ncomms8808  0.45
2015 Jepsen KJ, Lane NE, Healey JH, Tosi LL. Editorial Comment: Symposium: Sex Differences in Musculoskeletal Disease and Science. Clinical Orthopaedics and Related Research. 473: 2474-8. PMID 26077610 DOI: 10.1007/S11999-015-4368-9  0.306
2015 Jepsen KJ, Silva MJ, Vashishth D, Guo XE, van der Meulen MC. Establishing biomechanical mechanisms in mouse models: practical guidelines for systematically evaluating phenotypic changes in the diaphyses of long bones. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 951-66. PMID 25917136 DOI: 10.1002/Jbmr.2539  0.627
2015 Schlecht SH, Bigelow EM, Jepsen KJ. How Does Bone Strength Compare Across Sex, Site, and Ethnicity? Clinical Orthopaedics and Related Research. PMID 25739343 DOI: 10.1007/S11999-015-4229-6  0.56
2015 Jepsen KJ, Bigelow EM, Schlecht SH. Women Build Long Bones With Less Cortical Mass Relative to Body Size and Bone Size Compared With Men. Clinical Orthopaedics and Related Research. PMID 25690167 DOI: 10.1007/S11999-015-4184-2  0.544
2015 Khoury BM, Bigelow EM, Smith LM, Schlecht SH, Scheller EL, Andarawis-Puri N, Jepsen KJ. The use of nano-computed tomography to enhance musculoskeletal research. Connective Tissue Research. 56: 106-19. PMID 25646568 DOI: 10.1017/S1431927614005601  0.322
2014 Smith LM, Bigelow EM, Nolan BT, Faillace ME, Nadeau JH, Jepsen KJ. Genetic perturbations that impair functional trait interactions lead to reduced bone strength and increased fragility in mice. Bone. 67: 130-8. PMID 25003813 DOI: 10.1016/J.Bone.2014.06.035  0.562
2014 Schlecht SH, Bigelow EM, Jepsen KJ. Mapping the natural variation in whole bone stiffness and strength across skeletal sites. Bone. 67: 15-22. PMID 24999223 DOI: 10.1016/J.Bone.2014.06.031  0.616
2014 Goldman HM, Hampson NA, Guth JJ, Lin D, Jepsen KJ. Intracortical remodeling parameters are associated with measures of bone robustness. Anatomical Record (Hoboken, N.J. : 2007). 297: 1817-28. PMID 24962664 DOI: 10.1002/Ar.22962  0.606
2014 Jepsen KJ, Schlecht SH, Kozloff KM. Are we taking full advantage of the growing number of pharmacological treatment options for osteoporosis? Current Opinion in Pharmacology. 16: 64-71. PMID 24747363 DOI: 10.1016/J.Coph.2014.03.006  0.385
2014 Jepsen KJ, Schlecht SH. Biomechanical mechanisms: resolving the apparent conundrum of why individuals with type II diabetes show increased fracture incidence despite having normal BMD. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 784-6. PMID 24496824 DOI: 10.1002/Jbmr.2189  0.386
2014 Schlecht SH, Jepsen KJ. Corrigendum to "Functional integration of skeletal traits: An intraskeletal assessment of bone size, mineralization, and volume covariance" [Bone 56 (2013) 127-138] Bone. 62: 69-70. DOI: 10.1016/J.Bone.2014.01.024  0.584
2013 Smith L, Bigelow EM, Jepsen KJ. Systematic evaluation of skeletal mechanical function. Current Protocols in Mouse Biology. 3: 39-67. PMID 24634803 DOI: 10.1002/9780470942390.Mo130027  0.486
2013 Aslam MN, Bergin I, Jepsen K, Kreider JM, Graf KH, Naik M, Goldstein SA, Varani J. Preservation of bone structure and function by Lithothamnion sp. derived minerals. Biological Trace Element Research. 156: 210-20. PMID 24096551 DOI: 10.1007/S12011-013-9820-7  0.595
2013 Schlecht SH, Jepsen KJ. Functional integration of skeletal traits: an intraskeletal assessment of bone size, mineralization, and volume covariance. Bone. 56: 127-38. PMID 23721816 DOI: 10.1016/J.Bone.2013.05.012  0.6
2013 Jepsen KJ, Evans R, Negus CH, Gagnier JJ, Centi A, Erlich T, Hadid A, Yanovich R, Moran DS. Variation in tibial functionality and fracture susceptibility among healthy, young adults arises from the acquisition of biologically distinct sets of traits. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1290-300. PMID 23362125 DOI: 10.1002/Jbmr.1879  0.5
2012 Pathak S, Vachhani SJ, Jepsen KJ, Goldman HM, Kalidindi SR. Assessment of lamellar level properties in mouse bone utilizing a novel spherical nanoindentation data analysis method. Journal of the Mechanical Behavior of Biomedical Materials. 13: 102-17. PMID 22842281 DOI: 10.1016/J.Jmbbm.2012.03.018  0.537
2012 Jepsen KJ, Andarawis-Puri N. The amount of periosteal apposition required to maintain bone strength during aging depends on adult bone morphology and tissue-modulus degradation rate. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1916-26. PMID 22532507 DOI: 10.1002/Jbmr.1643  0.619
2012 Epelboym Y, Gendron RN, Mayer J, Fusco J, Nasser P, Gross G, Ghillani R, Jepsen KJ. The interindividual variation in femoral neck width is associated with the acquisition of predictable sets of morphological and tissue-quality traits and differential bone loss patterns. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1501-10. PMID 22461103 DOI: 10.1002/Jbmr.1614  0.521
2012 Sereysky JB, Andarawis-Puri N, Jepsen KJ, Flatow EL. Structural and mechanical effects of in vivo fatigue damage induction on murine tendon. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 965-72. PMID 22072573 DOI: 10.1002/Jor.22012  0.321
2011 Jepsen KJ, Centi A, Duarte GF, Galloway K, Goldman H, Hampson N, Lappe JM, Cullen DM, Greeves J, Izard R, Nindl BC, Kraemer WJ, Negus CH, Evans RK. Biological constraints that limit compensation of a common skeletal trait variant lead to inequivalence of tibial function among healthy young adults. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2872-85. PMID 21898595 DOI: 10.1002/Jbmr.497  0.625
2011 Grimes R, Jepsen KJ, Fitch JL, Einhorn TA, Gerstenfeld LC. The transcriptome of fracture healing defines mechanisms of coordination of skeletal and vascular development during endochondral bone formation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2597-609. PMID 21826735 DOI: 10.1002/Jbmr.486  0.531
2011 Bhola S, Chen J, Fusco J, Duarte GF, Andarawis-Puri N, Ghillani R, Jepsen KJ. Variation in childhood skeletal robustness is an important determinant of cortical area in young adults. Bone. 49: 799-809. PMID 21810492 DOI: 10.1016/J.Bone.2011.07.018  0.558
2011 Izu Y, Sun M, Zwolanek D, Veit G, Williams V, Cha B, Jepsen KJ, Koch M, Birk DE. Type XII collagen regulates osteoblast polarity and communication during bone formation. The Journal of Cell Biology. 193: 1115-30. PMID 21670218 DOI: 10.1083/Jcb.201010010  0.556
2011 Courtland HW, Elis S, Wu Y, Sun H, Rosen CJ, Jepsen KJ, Yakar S. Serum IGF-1 affects skeletal acquisition in a temporal and compartment-specific manner. Plos One. 6: e14762. PMID 21445249 DOI: 10.1371/Journal.Pone.0014762  0.585
2011 Arteaga-Solis E, Sui-Arteaga L, Kim M, Schaffler MB, Jepsen KJ, Pleshko N, Ramirez F. Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils. Matrix Biology : Journal of the International Society For Matrix Biology. 30: 188-94. PMID 21440062 DOI: 10.1016/J.Matbio.2011.03.004  0.59
2011 Jepsen KJ. Functional interactions among morphologic and tissue quality traits define bone quality. Clinical Orthopaedics and Related Research. 469: 2150-9. PMID 21125361 DOI: 10.1007/S11999-010-1706-9  0.546
2011 Pathak S, Swadener JG, Kalidindi SR, Courtland HW, Jepsen KJ, Goldman HM. Measuring the dynamic mechanical response of hydrated mouse bone by nanoindentation. Journal of the Mechanical Behavior of Biomedical Materials. 4: 34-43. PMID 21094478 DOI: 10.1016/J.Jmbbm.2010.09.002  0.605
2011 Nowlan NC, Jepsen KJ, Morgan EF. Smaller, weaker, and less stiff bones evolve from changes in subsistence strategy. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 22: 1967-80. PMID 20857281 DOI: 10.1007/S00198-010-1390-3  0.59
2011 Hampson NA, Jepsen KJ, Kalidindi SR, Duarte GF, Goldman HM. Regional Variation in Canal Volume of the Human Tibial Cortex The Faseb Journal. 25. DOI: 10.1096/Fasebj.25.1_Supplement.488.8  0.421
2010 Herman BC, Cardoso L, Majeska RJ, Jepsen KJ, Schaffler MB. Activation of bone remodeling after fatigue: Differential response to linear microcracks and diffuse damage Bone. 47: 766-772. PMID 20633708 DOI: 10.1016/J.Bone.2010.07.006  0.448
2010 Bouxsein ML, Boyd SK, Christiansen BA, Guldberg RE, Jepsen KJ, Müller R. Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1468-86. PMID 20533309 DOI: 10.1002/Jbmr.141  0.521
2010 Jepsen KJ, Courtland HW, Nadeau JH. Genetically determined phenotype covariation networks control bone strength. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1581-93. PMID 20200957 DOI: 10.1002/Jbmr.41  0.603
2010 Elis S, Courtland HW, Wu Y, Rosen CJ, Sun H, Jepsen KJ, Majeska RJ, Yakar S. Elevated serum levels of IGF-1 are sufficient to establish normal body size and skeletal properties even in the absence of tissue IGF-1. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1257-66. PMID 20200935 DOI: 10.1002/Jbmr.20  0.343
2010 Gerstenfeld LC, McLean J, Healey DS, Stapleton SN, Silkman LJ, Price C, Jepsen KJ. Genetic variation in the structural pattern of osteoclast activity during post-natal growth of mouse femora. Bone. 46: 1546-54. PMID 20178867 DOI: 10.1016/J.Bone.2010.02.016  0.459
2010 Simonaro CM, Ge Y, Eliyahu E, He X, Jepsen KJ, Schuchman EH. Involvement of the Toll-like receptor 4 pathway and use of TNF-alpha antagonists for treatment of the mucopolysaccharidoses. Proceedings of the National Academy of Sciences of the United States of America. 107: 222-7. PMID 20018674 DOI: 10.1073/Pnas.0912937107  0.369
2010 Fung DT, Wang VM, Andarawis-Puri N, Basta-Pljakic J, Li Y, Laudier DM, Sun HB, Jepsen KJ, Schaffler MB, Flatow EL. Early response to tendon fatigue damage accumulation in a novel in vivo model. Journal of Biomechanics. 43: 274-9. PMID 19939387 DOI: 10.1016/J.Jbiomech.2009.08.039  0.314
2010 Emerton KB, Hu B, Woo AA, Sinofsky A, Hernandez C, Majeska RJ, Jepsen KJ, Schaffler MB. Osteocyte apoptosis and control of bone resorption following ovariectomy in mice. Bone. 46: 577-83. PMID 19925896 DOI: 10.1016/J.Bone.2009.11.006  0.507
2010 Pinto M, Jepsen KJ, Terranova CJ, Buffenstein R. Lack of sexual dimorphism in femora of the eusocial and hypogonadic naked mole-rat: A novel animal model for the study of delayed puberty on the skeletal system Bone. 46: 112-120. PMID 19761882 DOI: 10.1016/J.Bone.2009.08.060  0.482
2009 Jepsen KJ. Systems analysis of bone. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 1: 73-88. PMID 20046860 DOI: 10.1002/Wsbm.15  0.587
2009 Pandey N, Bhola S, Goldstone A, Chen F, Chrzanowski J, Terranova CJ, Ghillani R, Jepsen KJ. Interindividual variation in functionally adapted trait sets is established during postnatal growth and predictable based on bone robustness. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 1969-80. PMID 20001599 DOI: 10.1359/Jbmr.090525  0.47
2009 Yakar S, Canalis E, Sun H, Mejia W, Kawashima Y, Nasser P, Courtland HW, Williams V, Bouxsein M, Rosen C, Jepsen KJ. Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 1481-92. PMID 19257833 DOI: 10.1359/Jbmr.090226  0.554
2009 Kawashima Y, Fritton JC, Yakar S, Epstein S, Schaffler MB, Jepsen KJ, LeRoith D. Type 2 diabetic mice demonstrate slender long bones with increased fragility secondary to increased osteoclastogenesis. Bone. 44: 648-55. PMID 19150422 DOI: 10.1016/J.Bone.2008.12.012  0.574
2009 Lichtblau S, Gallina J, Nasser P, Munyoki M, Jepsen K. A biomechanical comparison of two patterns of screw insertion. Bulletin of the Nyu Hospital For Joint Diseases. 66: 269-71. PMID 19093901  0.367
2009 Jepsen KJ, Hu B, Tommasini SM, Courtland HW, Price C, Cordova M, Nadeau JH. Phenotypic integration of skeletal traits during growth buffers genetic variants affecting the slenderness of femora in inbred mouse strains. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 21-33. PMID 19082857 DOI: 10.1007/S00335-008-9158-1  0.731
2009 Tommasini SM, Hu B, Nadeau JH, Jepsen KJ. Phenotypic integration among trabecular and cortical bone traits establishes mechanical functionality of inbred mouse vertebrae. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 606-20. PMID 19063678 DOI: 10.1359/Jbmr.081224  0.781
2009 Yakar S, Rosen CJ, Bouxsein ML, Sun H, Mejia W, Kawashima Y, Wu Y, Emerton K, Williams V, Jepsen K, Schaffler MB, Majeska RJ, Gavrilova O, Gutierrez M, Hwang D, et al. Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 709-19. PMID 18952711 DOI: 10.1096/Fj.08-118976  0.366
2009 Courtland HW, Spevak M, Boskey AL, Jepsen KJ. Genetic variation in mouse femoral tissue-level mineral content underlies differences in whole bone mechanical properties. Cells, Tissues, Organs. 189: 237-40. PMID 18703864 DOI: 10.1159/000151381  0.482
2009 Fung DT, Wang VM, Laudier DM, Shine JH, Basta-Pljakic J, Jepsen KJ, Schaffler MB, Flatow EL. Subrupture tendon fatigue damage. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 27: 264-73. PMID 18683881 DOI: 10.1002/Jor.20722  0.308
2009 Bhola S, Pandey N, Ghillani R, Jepsen KJ. Inter-individual variation in skeletal growth patterns is predictable based on bone robusticity Bone. 45. DOI: 10.1016/J.Bone.2009.04.154  0.49
2009 Greene EL, Jepsen KJ, Gordish-Dressman H, Brandoli C, Hoffman EP, Devaney JM, Tosi LL. Sexual dimorphism and variations in mechanical loading influence humeral bone volume in the young adult skeleton Bone. 45. DOI: 10.1016/J.Bone.2009.04.030  0.47
2008 Shao H, Burrage LC, Sinasac DS, Hill AE, Ernest SR, O'Brien W, Courtland HW, Jepsen KJ, Kirby A, Kulbokas EJ, Daly MJ, Broman KW, Lander ES, Nadeau JH. Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 19910-4. PMID 19066216 DOI: 10.1073/Pnas.0810388105  0.361
2008 Courtland HW, Nasser P, Goldstone AB, Spevak L, Boskey AL, Jepsen KJ. Fourier transform infrared imaging microspectroscopy and tissue-level mechanical testing reveal intraspecies variation in mouse bone mineral and matrix composition. Calcified Tissue International. 83: 342-53. PMID 18855037 DOI: 10.1007/S00223-008-9176-8  0.578
2008 Wiren KM, Semirale AA, Zhang XW, Woo A, Tommasini SM, Price C, Schaffler MB, Jepsen KJ. Targeting of androgen receptor in bone reveals a lack of androgen anabolic action and inhibition of osteogenesis: a model for compartment-specific androgen action in the skeleton. Bone. 43: 440-51. PMID 18595795 DOI: 10.1016/J.Bone.2008.04.026  0.779
2008 Jepsen KJ, Price C, Silkman LJ, Nicholls FH, Nasser P, Hu B, Hadi N, Alapatt M, Stapleton SN, Kakar S, Einhorn TA, Gerstenfeld LC. Genetic variation in the patterns of skeletal progenitor cell differentiation and progression during endochondral bone formation affects the rate of fracture healing. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 1204-16. PMID 18348700 DOI: 10.1359/Jbmr.080317  0.441
2008 Tommasini SM, Wearne SL, Hof PR, Jepsen KJ. Percolation theory relates corticocancellous architecture to mechanical function in vertebrae of inbred mouse strains. Bone. 42: 743-50. PMID 18258502 DOI: 10.1016/J.Bone.2007.12.009  0.748
2008 Tommasini SM, Nasser P, Hu B, Jepsen KJ. Biological co-adaptation of morphological and composition traits contributes to mechanical functionality and skeletal fragility. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 236-46. PMID 17922614 DOI: 10.1359/Jbmr.071014  0.787
2008 Hankenson KD, Shitaye H, Tommasini SM, Wang M, Jepsen KJ. Thrombospondins influence endocortical bone mass by regulating the pool of available marrow osteoprogenitors Bone. 42: S23. DOI: 10.1016/J.Bone.2007.12.024  0.75
2007 Jepsen KJ, Hu B, Tommasini SM, Courtland HW, Price C, Terranova CJ, Nadeau JH. Genetic randomization reveals functional relationships among morphologic and tissue-quality traits that contribute to bone strength and fragility. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 492-507. PMID 17557179 DOI: 10.1007/S00335-007-9017-5  0.776
2007 Joo W, Jepsen KJ, Davy DT. The effect of recovery time and test conditions on viscoelastic measures of tensile damage in cortical bone. Journal of Biomechanics. 40: 2731-7. PMID 17412349 DOI: 10.1016/J.Jbiomech.2007.01.005  0.387
2007 Tommasini SM, Nasser P, Jepsen KJ. Sexual dimorphism affects tibia size and shape but not tissue-level mechanical properties. Bone. 40: 498-505. PMID 17035111 DOI: 10.1016/J.Bone.2006.08.012  0.707
2007 Jepsen K, Hu B, Tommasini S, Courtland H, Price C, Terranova C, Nadeau J. Path analysis using data derived from genetically randomized inbred mouse strains reveals biological controls affecting bone growth and adult fragility Bone. 40: S53. DOI: 10.1016/J.Bone.2007.04.064  0.705
2006 Gerstenfeld LC, Alkhiary YM, Krall EA, Nicholls FH, Stapleton SN, Fitch JL, Bauer M, Kayal R, Graves DT, Jepsen KJ, Einhorn TA. Three-dimensional reconstruction of fracture callus morphogenesis. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 54: 1215-28. PMID 16864894 DOI: 10.1369/Jhc.6A6959.2006  0.509
2006 Li CY, Jepsen KJ, Majeska RJ, Zhang J, Ni R, Gelb BD, Schaffler MB. Mice lacking cathepsin K maintain bone remodeling but develop bone fragility despite high bone mass. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 865-75. PMID 16753017 DOI: 10.1359/Jbmr.060313  0.602
2006 Wang VM, Banack TM, Tsai CW, Flatow EL, Jepsen KJ. Variability in tendon and knee joint biomechanics among inbred mouse strains. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 24: 1200-7. PMID 16705702 DOI: 10.1002/Jor.20167  0.4
2005 Li CY, Schaffler MB, Wolde-Semait HT, Hernandez CJ, Jepsen KJ. Genetic background influences cortical bone response to ovariectomy. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 2150-8. PMID 16294268 DOI: 10.1359/Jbmr.050819  0.582
2005 Price C, Herman BC, Lufkin T, Goldman HM, Jepsen KJ. Genetic variation in bone growth patterns defines adult mouse bone fragility. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1983-91. PMID 16234972 DOI: 10.1359/Jbmr.050707  0.603
2005 Tommasini SM, Nasser P, Schaffler MB, Jepsen KJ. Relationship between bone morphology and bone quality in male tibias: implications for stress fracture risk. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1372-80. PMID 16007335 DOI: 10.1359/Jbmr.050326  0.764
2005 Tommasini SM, Morgan TG, van der Meulen MCh, Jepsen KJ. Genetic variation in structure-function relationships for the inbred mouse lumbar vertebral body. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 817-27. PMID 15824855 DOI: 10.1359/Jbmr.041234  0.791
2005 Li CY, Price C, Delisser K, Nasser P, Laudier D, Clement M, Jepsen KJ, Schaffler MB. Long-term disuse osteoporosis seems less sensitive to bisphosphonate treatment than other osteoporosis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 117-24. PMID 15619677 DOI: 10.1359/Jbmr.041010  0.59
2004 Tanck E, Van Donkelaar CC, Jepsen KJ, Goldstein SA, Weinans H, Burger EH, Huiskes R. The mechanical consequences of mineralization in embryonic bone Bone. 35: 186-190. PMID 15207755 DOI: 10.1016/J.Bone.2004.02.015  0.527
2004 Wiren KM, Zhang XW, Toombs AR, Kasparcova V, Gentile MA, Harada S, Jepsen KJ. Targeted overexpression of androgen receptor in osteoblasts: unexpected complex bone phenotype in growing animals. Endocrinology. 145: 3507-22. PMID 15131013 DOI: 10.1210/En.2003-1016  0.459
2004 Jepsen KJ, Nadeau J. How is Bone Fragility Inherited? The Effects of Gender and Parental Genotype Bmc News and Views. 4. DOI: 10.1186/2048-4623-4-S2-Op008  0.473
2003 Dean D, Topham NS, Meneghetti SC, Wolfe MS, Jepsen K, He S, Chen JE, Fisher JP, Cooke M, Rimnac C, Mikos AG. Poly(propylene fumarate) and poly(DL-lactic-co-glycolic acid) as scaffold materials for solid and foam-coated composite tissue-engineered constructs for cranial reconstruction. Tissue Engineering. 9: 495-504. PMID 12857417 DOI: 10.1089/107632703322066679  0.496
2003 Akkus O, Knott DF, Jepsen KJ, Davy DT, Rimnac CM. Relationship between damage accumulation and mechanical property degradation in cortical bone: microcrack orientation is important. Journal of Biomedical Materials Research. Part A. 65: 482-8. PMID 12761839 DOI: 10.1002/Jbm.A.10567  0.394
2003 Angele P, Yoo JU, Smith C, Mansour J, Jepsen KJ, Nerlich M, Johnstone B. Cyclic hydrostatic pressure enhances the chondrogenic phenotype of human mesenchymal progenitor cells differentiated in vitro. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 21: 451-7. PMID 12706017 DOI: 10.1016/S0736-0266(02)00230-9  0.36
2003 Jepsen KJ, Akkus OJ, Majeska RJ, Nadeau JH. Hierarchical relationship between bone traits and mechanical properties in inbred mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 97-104. PMID 12584605 DOI: 10.1007/S00335-002-3045-Y  0.601
2002 Jepsen KJ, Wu F, Peragallo JH, Paul J, Roberts L, Ezura Y, Oldberg A, Birk DE, Chakravarti S. A syndrome of joint laxity and impaired tendon integrity in lumican- and fibromodulin-deficient mice Journal of Biological Chemistry. 277: 35532-35540. PMID 12089156 DOI: 10.1074/Jbc.M205398200  0.315
2002 Ameye L, Aria D, Jepsen K, Oldberg AKE, Xu T, Young MF. Abnormal collagen fibrils in tendons of biglycan/fibromodulin-deficient mice lead to gait impairment, ectopic ossification, and osteoarthritis Faseb Journal. 16: 673-680. PMID 11978731 DOI: 10.1096/Fj.01-0848Com  0.375
2001 Jepsen KJ, Pennington DE, Lee YL, Warman M, Nadeau J. Bone brittleness varies with genetic background in A/J and C57BL/6J inbred mice Journal of Bone and Mineral Research. 16: 1854-1862. PMID 11585350 DOI: 10.1359/Jbmr.2001.16.10.1854  0.627
2001 Van der Meulen MCH, Jepsen KJ, Miki B. Understanding bone strength: Size isn't everything Bone. 29: 101-104. PMID 11502469 DOI: 10.1016/S8756-3282(01)00491-4  0.556
2000 Akkus O, Jepsen KJ, Rimnac CM. Microstructural aspects of the fracture process in human cortical bone Journal of Materials Science. 35: 6065-6074. DOI: 10.1023/A:1026719531300  0.355
2000 Schaffler MB, Jepsen KJ. Fatigue and repair in bone International Journal of Fatigue. 22: 839-846. DOI: 10.1016/S0142-1123(00)00053-0  0.568
1999 Dean D, Topham NS, Rimnac C, Mikos AG, Goldberg DP, Jepsen K, Redtfeldt R, Liu Q, Pennington D, Ratcheson R. Osseointegration of preformed polymethylmethacrylate craniofacial prostheses coated with bone marrow-impregnated poly (DL-lactic-co-glycolic acid) foam. Plastic and Reconstructive Surgery. 104: 705-12. PMID 10456522 DOI: 10.1097/00006534-199909030-00014  0.499
1999 Jepsen KJ, Davy DT, Krzypow DJ. The role of the lamellar interface during torsional yielding of human cortical bone Journal of Biomechanics. 32: 303-310. PMID 10093030 DOI: 10.1016/S0021-9290(98)00179-1  0.459
1999 Jepsen KJ, Pizzuto TM. Differences in bone brittleness between two genetically distinct inbred mouse strains American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 42: 401-402.  0.367
1999 Nicolella DP, Moravits DE, Siller-Jackson AJ, Railsback RJ, Timmons SF, Jepsen KJ, Davy DT, Lankford J. Ultrastructural characterization of damaged cortical bone using atomic force microscopy American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 42: 319-320.  0.337
1997 Jepsen KJ, Schaffler MB, Kuhn JL, Goulet RW, Bonadio J, Goldstein SA. Type I collagen mutation alters the strength and fatigue behavior of Mov13 cortical tissue Journal of Biomechanics. 30: 1141-1147. PMID 9456382 DOI: 10.1016/S0021-9290(97)00088-2  0.477
1997 Jepsen KJ, Davy DT. Comparison of damage accumulation measures in human cortical bone Journal of Biomechanics. 30: 891-894. PMID 9302611 DOI: 10.1016/S0021-9290(97)00036-5  0.562
1997 Jepsen KJ, Krzypow DJ, Davy DT. Physical and mechanical evidence of shear damage accumulation in human cortical bone American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 35: 307-308.  0.418
1997 Nicolella DP, Lankford J, Jepsen KJ, Davy DT. Correlation of physical damage development with microstructure and strain localization in bone American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 35: 311-312.  0.422
1996 Jepsen KJ, Goldstein SA, Kuhn JL, Schaffler MB, Bonadio J. Type-I collagen mutation compromises the post-yield behavior of Mov13 long bone Journal of Orthopaedic Research. 14: 493-499. PMID 8676263 DOI: 10.1002/Jor.1100140320  0.573
1996 Jepsen KJ, Davy DT. The effects of prior damage on the rate-dependent torsional strength of human cortical bone American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 33: 313-314.  0.468
1993 Bonadio J, Jepsen KJ, Mansoura MK, Jaenisch R, Kuhn JL, Goldstein SA. A murine skeletal adaptation that significantly increases cortical bone mechanical properties implications for human skeletal fragility Journal of Clinical Investigation. 92: 1697-1705. PMID 8408623 DOI: 10.1172/Jci116756  0.565
1993 Lewis DB, Liggitt HD, Effmann EL, Motley ST, Teitelbaum SL, Jepsen KJ, Goldstein SA, Bonadio J, Carpenter J, Perlmutter RM. Osteoporosis induced in mice by overproduction of interleukin 4 Proceedings of the National Academy of Sciences of the United States of America. 90: 11618-11622. PMID 8265598 DOI: 10.1073/Pnas.90.24.11618  0.507
1991 Hollister SJ, Fyhrie DP, Jepsen KJ, Goldstein SA. Application of homogenization theory to the study of trabecular bone mechanics Journal of Biomechanics. 24: 825-839. PMID 1752867 DOI: 10.1016/0021-9290(91)90308-A  0.566
1990 Fyhrie D, Hollister S, Jepsen K. Approximating the microstructural prediction of cancellous bone strength using the Tsai-Wu failure criterion Journal of Biomechanics. 23: 714. DOI: 10.1016/0021-9290(90)90183-4  0.498
1989 Hollister SJ, Fyhrie DP, Jepsen KJ, Goldstein SA. Analysis of trabecuar bone micro-mechanics using homogenization theory with comparison to experimental results Journal of Biomechanics. 22: 1025. DOI: 10.1016/0021-9290(89)90284-4  0.404
1989 Fyhrie DP, Jepsen KJ, Hollister SJ, Goldstein SA. Predicting trabecular bone strength and micro-strain using homogenization theory Journal of Biomechanics. 22: 1014. DOI: 10.1016/0021-9290(89)90251-0  0.452
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