Beth A. Winkelstein - Publications

Affiliations: 
Bioengineering University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biomedical Engineering, Biomechanics Biophysics, Neuroscience Biology

161 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kent AR, Weisshaar CL, Venkatesan L, Winkelstein BA. Burst & High-Frequency Spinal Cord Stimulation Differentially Effect Spinal Neuronal Activity After Radiculopathy. Annals of Biomedical Engineering. PMID 31385104 DOI: 10.1007/s10439-019-02336-8  0.44
2019 Barocas VH, Winkelstein BA. Editors' Choice Papers for 2018. Journal of Biomechanical Engineering. PMID 30840049 DOI: 10.1115/1.4043072  0.36
2018 Chan VWL, Tobin WR, Zhang S, Winkelstein BA, Barocas VH, Shephard MS, Picu CR. Image-based multi-scale mechanical analysis of strain amplification in neurons embedded in collagen gel. Computer Methods in Biomechanics and Biomedical Engineering. 1-16. PMID 30450957 DOI: 10.1080/10255842.2018.1538414  0.48
2018 Kartha S, Weisshaar CL, Philips BH, Winkelstein BA. Pre-treatment with Meloxicam Prevents the Spinal Inflammation and Oxidative Stress in DRG Neurons that Accompany Painful Cervical Radiculopathy. Neuroscience. PMID 30086368 DOI: 10.1016/j.neuroscience.2018.07.054  0.44
2018 Kartha S, Bulka BA, Stiansen NS, Troche HR, Winkelstein BA. Repeated High Rate Facet Capsular Stretch at Strains That are Below the Pain Threshold Induces Pain and Spinal Inflammation With Decreased Ligament Strength in the Rat. Journal of Biomechanical Engineering. 140. PMID 30003250 DOI: 10.1115/1.4040023  0.6
2018 Singh S, Kartha S, Bulka BA, Stiansen NS, Winkelstein BA. Physiologic facet capsule stretch can induce pain & upregulate matrix metalloproteinase-3 in the dorsal root ganglia when preceded by a physiological mechanical or nonpainful chemical exposure. Clinical Biomechanics (Bristol, Avon). PMID 29523370 DOI: 10.1016/j.clinbiomech.2018.01.009  0.6
2017 Erdemir A, Hunter PJ, Holzapfel GA, Loew LM, Middleton J, Jacobs CR, Nithiarasu P, Lohner R, Wei G, Winkelstein BA, Barocas VH, Guilak F, Ku J, Hicks JL, Delp S, et al. Perspectives on Sharing Models and Related Resources in Computational Biomechanics Research. Journal of Biomechanical Engineering. PMID 29247253 DOI: 10.1115/1.4038768  0.36
2017 Zarei V, Zhang S, Winkelstein BA, Barocas VH. Tissue loading and microstructure regulate the deformation of embedded nerve fibres: predictions from single-scale and multiscale simulations. Journal of the Royal Society, Interface. 14. PMID 28978743 DOI: 10.1098/rsif.2017.0326  0.48
2017 Zhang S, Zhao E, Winkelstein BA. A Nociceptive Role for Integrin Signaling in Pain After Mechanical Injury to the Spinal Facet Capsular Ligament. Annals of Biomedical Engineering. PMID 28924864 DOI: 10.1007/s10439-017-1917-2  0.48
2017 Zhang S, Zarei V, Winkelstein BA, Barocas VH. Multiscale mechanics of the cervical facet capsular ligament, with particular emphasis on anomalous fiber realignment prior to tissue failure. Biomechanics and Modeling in Mechanobiology. PMID 28821971 DOI: 10.1007/s10237-017-0949-8  0.48
2017 Zhang S, Singh S, Winkelstein BA. Collagen organization regulates stretch-initiated pain-related neuronal signals in vitro: Implications for structure-function relationships in innervated ligaments. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28722281 DOI: 10.1002/jor.23657  0.48
2017 Weisshaar CL, Kras JV, Pall PS, Kartha S, Winkelstein BA. Ablation of IB4 non-peptidergic afferents in the rat facet joint prevents injury-induced pain and thalamic hyperexcitability via supraspinal glutamate transporters. Neuroscience Letters. 655: 82-89. PMID 28689926 DOI: 10.1016/j.neulet.2017.07.006  0.44
2017 Kartha S, Yan L, Weisshaar CL, Ita ME, Shuvaev VV, Muzykantov VR, Tsourkas A, Winkelstein BA, Cheng Z. Superoxide Dismutase-Loaded Porous Polymersomes as Highly Efficient Antioxidants for Treating Neuropathic Pain. Advanced Healthcare Materials. PMID 28671302 DOI: 10.1002/adhm.201700500  0.44
2017 Ita ME, Zhang S, Holsgrove TP, Kartha S, Winkelstein BA. The Physiological Basis of Cervical Facet-Mediated Persistent Pain: Basic Science and Clinical Challenges. The Journal of Orthopaedic and Sports Physical Therapy. 1-36. PMID 28622486 DOI: 10.2519/jospt.2017.7255  0.48
2017 Ban E, Zhang S, Zarei V, Barocas VH, Winkelstein BA, Picu CR. Collagen Organization in Facet Capsular Ligaments Varies with Spinal Region and with Ligament Deformation. Journal of Biomechanical Engineering. PMID 28241270 DOI: 10.1115/1.4036019  0.48
2017 Philips BH, Weisshaar CL, Winkelstein BA. Use of the Rat Grimace Scale to Evaluate Neuropathic Pain in a Model of Cervical Radiculopathy. Comparative Medicine. 67: 34-42. PMID 28222837  0.44
2017 Smith JR, Lee J, Winkelstein BA. Nerve Root Compression Increases Spinal Astrocytic Vimentin in Parallel with Sustained Pain and Endothelial Vimentin in Association with Spinal Vascular Reestablishment. Spine. PMID 28169954 DOI: 10.1097/BRS.0000000000002103  0.48
2017 Smith JR, Winkelstein BA. The role of spinal thrombin through protease-activated receptor 1 in hyperalgesia after neural injury. Journal of Neurosurgery. Spine. 1-10. PMID 28059686 DOI: 10.3171/2016.9.SPINE16501  0.48
2017 Winkelstein BA, Barocas VH. Thank you to Reviewers. Journal of Biomechanical Engineering. PMID 28056155 DOI: 10.1115/1.4035652  0.36
2017 Winkelstein BA, Barocas VH. Year in Review. Journal of Biomechanical Engineering. PMID 28056154 DOI: 10.1115/1.4035641  0.36
2017 Winkelstein BA, Barocas VH. 2016 Richard Skalak Award. Journal of Biomechanical Engineering. PMID 28056147 DOI: 10.1115/1.4035653  0.36
2017 Winkelstein BA, Barocas VH. Journal of Biomechanical Engineering - Legacy Paper. Journal of Biomechanical Engineering. PMID 28056131 DOI: 10.1115/1.4035642  0.36
2017 Winkelstein BA, Barocas VH. Society Awards. Journal of Biomechanical Engineering. PMID 28056126 DOI: 10.1115/1.4035645  0.36
2017 Winkelstein BA, Barocas VH. Student Paper Awards. Journal of Biomechanical Engineering. PMID 28056113 DOI: 10.1115/1.4035643  0.36
2016 Barr GA, Wang S, Weisshaar CL, Winkelstein BA. Developmental Changes in Pain and Spinal Immune Gene Expression after Radicular Trauma in the Rat. Frontiers in Neurology. 7: 223. PMID 28018284 DOI: 10.3389/fneur.2016.00223  0.44
2016 Ita ME, Crosby ND, Bulka BA, Winkelstein BA. Painful Cervical Facet Joint Injury is Accompianed by Changes in The Number Of Excitatory and Inhibitory Synapses in The Superficial Dorsal Horn that Differentially Relate to Local Tissue Injury Severity. Spine. PMID 27755498 DOI: 10.1097/BRS.0000000000001934  0.96
2016 Zeeman ME, Kartha S, Winkelstein BA. Whole-body vibration induces pain and lumbar spinal inflammation responses in the rat that vary with the vibration profile. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 34: 1439-46. PMID 27571442 DOI: 10.1002/jor.23243  0.48
2016 Barocas VH, Winkelstein BA. 2015 Summer Biomechanics, Bioengineering, and Biotransport Conference Student Paper Competition. Journal of Biomechanical Engineering. 138. PMID 27271149 DOI: 10.1115/1.4032189  0.36
2016 Crosby ND, Winkelstein BA. Spinal Astrocytic Thrombospondin-4 Induced by Excitatory Neuronal Signaling Mediates Pain After Facet Capsule Injury. Annals of Biomedical Engineering. PMID 27160673 DOI: 10.1007/s10439-016-1639-x  1
2016 Zhang S, Bassett DS, Winkelstein BA. Stretch-induced network reconfiguration of collagen fibres in the human facet capsular ligament. Journal of the Royal Society, Interface / the Royal Society. 13. PMID 26819333 DOI: 10.1098/rsif.2015.0883  1
2016 Zeeman ME, Kartha S, Winkelstein BA. Whole-body vibration induces pain and lumbar spinal inflammation responses in the rat that vary with the vibration profile Journal of Orthopaedic Research. DOI: 10.1002/jor.23243  1
2015 Jaumard NV, Leung J, Gokhale AJ, Guarino BB, Welch WC, Winkelstein BA. Relevant Anatomic and Morphological Measurements of the Rat Spine: Considerations for Rodent Models of Human Spine Trauma. Spine. 40: E1084-92. PMID 26731709 DOI: 10.1097/BRS.0000000000001021  1
2015 Smith JR, Galie PA, Slochower DR, Weisshaar CL, Janmey PA, Winkelstein BA. Salmon-derived thrombin inhibits development of chronic pain through an endothelial barrier protective mechanism dependent on APC. Biomaterials. 80: 96-105. PMID 26708087 DOI: 10.1016/j.biomaterials.2015.11.062  1
2015 Zhang S, Cao X, Stablow A, Shenoy V, Winkelstein BA. Tissue Strain Reorganizes Collagen with a Switch-Like Response That Regulates Neuronal ERK Phosphorylation in Vitro: Implications for Ligamentous Injury & Mechanotransduction. Journal of Biomechanical Engineering. PMID 26549105 DOI: 10.1115/1.4031975  1
2015 Kartha S, Zhou T, Granquist EJ, Winkelstein BA. Development of a Rat Model of Mechanically Induced Tunable Pain and Associated Temporomandibular Joint Responses. Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. PMID 26433038 DOI: 10.1016/j.joms.2015.09.005  1
2015 Kras JV, Weisshaar CL, Pall PS, Winkelstein BA. Pain from intra-articular NGF or joint injury in the rat requires contributions from peptidergic joint afferents. Neuroscience Letters. 604: 193-8. PMID 26240991 DOI: 10.1016/j.neulet.2015.07.043  1
2015 Zeeman ME, Kartha S, Jaumard NV, Baig HA, Stablow AM, Lee J, Guarino BB, Winkelstein BA. Whole-body Vibration at Thoracic Resonance Induces Sustained Pain and Widespread Cervical Neuroinflammation in the Rat. Clinical Orthopaedics and Related Research. PMID 25917423 DOI: 10.1007/s11999-015-4315-9  1
2015 Crosby N, Weisshaar C, Smith J, Zeeman M, Goodman-Keiser M, Winkelstein B. Burst & Tonic Spinal Cord Stimulation Differentially Activate GABAergic Mechanisms to Attenuate Pain in a Rat Model of Cervical Radiculopathy. Ieee Transactions On Bio-Medical Engineering. PMID 25667344 DOI: 10.1109/TBME.2015.2399374  1
2015 Crosby ND, Zaucke F, Kras JV, Dong L, Luo ZD, Winkelstein BA. Thrombospondin-4 and excitatory synaptogenesis promote spinal sensitization after painful mechanical joint injury. Experimental Neurology. 264: 111-20. PMID 25483397 DOI: 10.1016/j.expneurol.2014.11.015  1
2015 Crosby ND, Goodman Keiser MD, Smith JR, Zeeman ME, Winkelstein BA. Stimulation parameters define the effectiveness of burst spinal cord stimulation in a rat model of neuropathic pain. Neuromodulation : Journal of the International Neuromodulation Society. 18: 1-8; discussion 8. PMID 25145400 DOI: 10.1111/ner.12221  1
2015 Kras JV, Kartha S, Winkelstein BA. Intra-articular nerve growth factor regulates development, but not maintenance, of injury-induced facet joint pain & spinal neuronal hypersensitivity Osteoarthritis and Cartilage. 23: 1999-2008. DOI: 10.1016/j.joca.2015.06.012  1
2015 Crosby ND, Smith JR, Winkelstein BA. Pain biomechanics Accidental Injury: Biomechanics and Prevention. 549-580. DOI: 10.1007/978-1-4939-1732-7_19  1
2014 Baig HA, Dorman DB, Bulka BA, Shivers BL, Chancey VC, Winkelstein BA. Characterization of the frequency and muscle responses of the lumbar and thoracic spines of seated volunteers during sinusoidal whole body vibration. Journal of Biomechanical Engineering. 136: 101002. PMID 25010637 DOI: 10.1115/1.4027998  1
2014 Crosby ND, Gilliland TM, Winkelstein BA. Early afferent activity from the facet joint after painful trauma to its capsule potentiates neuronal excitability and glutamate signaling in the spinal cord. Pain. 155: 1878-87. PMID 24978827 DOI: 10.1016/j.pain.2014.06.019  1
2014 Kartha S, Zeeman ME, Baig HA, Guarino BB, Winkelstein BA. Upregulation of BDNF and NGF in cervical intervertebral discs exposed to painful whole-body vibration Spine. 39: 1542-1548. PMID 24921856 DOI: 10.1097/BRS.0000000000000457  1
2014 Syré PP, Weisshaar CL, Winkelstein BA. Sustained neuronal hyperexcitability is evident in the thalamus after a transient cervical radicular injury. Spine. 39: E870-7. PMID 24827526 DOI: 10.1097/BRS.0000000000000392  1
2014 Nicholson KJ, Zhang S, Gilliland TM, Winkelstein BA. Riluzole effects on behavioral sensitivity and the development of axonal damage and spinal modifications that occur after painful nerve root compression. Journal of Neurosurgery. Spine. 20: 751-62. PMID 24678596 DOI: 10.3171/2014.2.SPINE13672  1
2014 Jaumard NV, Udupa JK, Welch WC, Winkelstein BA. Kinematic magnetic resonance imaging to define the cervical facet joint space for the spine in neutral and torsion. Spine. 39: 664-72. PMID 24430715 DOI: 10.1097/BRS.0000000000000206  1
2014 Weisshaar CL, Winkelstein BA. Ablating spinal NK1-bearing neurons eliminates the development of pain and reduces spinal neuronal hyperexcitability and inflammation from mechanical joint injury in the rat. The Journal of Pain : Official Journal of the American Pain Society. 15: 378-86. PMID 24389017 DOI: 10.1016/j.jpain.2013.12.003  1
2014 Kras JV, Dong L, Winkelstein BA. Increased interleukin-1α and prostaglandin E2 expression in the spinal cord at 1 day after painful facet joint injury: evidence of early spinal inflammation. Spine. 39: 207-12. PMID 24253784 DOI: 10.1097/BRS.0000000000000107  1
2014 Nicholson KJ, Gilliland TM, Winkelstein BA. Upregulation of GLT-1 by treatment with ceftriaxone alleviates radicular pain by reducing spinal astrocyte activation and neuronal hyperexcitability. Journal of Neuroscience Research. 92: 116-29. PMID 24123246 DOI: 10.1002/jnr.23295  1
2014 Winkelstein BA, Allen KD, Setton LA. Intervertebral disc herniation: Pathophysiology and emerging therapies The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease. 305-326. DOI: 10.1007/978-3-7091-1535-0_19  1
2013 Zhang S, Nicholson KJ, Smith JR, Gilliland TM, Syré PP, Winkelstein BA. The roles of mechanical compression and chemical irritation in regulating spinal neuronal signaling in painful cervical nerve root injury. Stapp Car Crash Journal. 57: 219-42. PMID 24435733  1
2013 Smith JR, Syre PP, Oake SA, Nicholson KJ, Weisshaar CL, Cruz K, Bucki R, Baumann BC, Janmey PA, Winkelstein BA. Salmon and human thrombin differentially regulate radicular pain, glial-induced inflammation and spinal neuronal excitability through protease-activated receptor-1. Plos One. 8: e80006. PMID 24278231 DOI: 10.1371/journal.pone.0080006  1
2013 Dong L, Crosby ND, Winkelstein BA. Gabapentin alleviates facet-mediated pain in the rat through reduced neuronal hyperexcitability and astrocytic activation in the spinal cord. The Journal of Pain : Official Journal of the American Pain Society. 14: 1564-72. PMID 24094695 DOI: 10.1016/j.jpain.2013.07.016  1
2013 Jaumard NV, Udupa JK, Siegler S, Schuster JM, Hilibrand AS, Hirsch BE, Borthakur A, Winkelstein BA. Three-dimensional kinematic stress magnetic resonance image analysis shows promise for detecting altered anatomical relationships of tissues in the cervical spine associated with painful radiculopathy Medical Hypotheses. 81: 738-744. PMID 23942030 DOI: 10.1016/j.mehy.2013.07.043  1
2013 Kras JV, Weisshaar CL, Quindlen J, Winkelstein BA. Brain-derived neurotrophic factor is upregulated in the cervical dorsal root ganglia and spinal cord and contributes to the maintenance of pain from facet joint injury in the rat. Journal of Neuroscience Research. 91: 1312-21. PMID 23918351 DOI: 10.1002/jnr.23254  1
2013 Baig HA, Guarino BB, Lipschutz D, Winkelstein BA. Whole body vibration induces forepaw and hind paw behavioral sensitivity in the rat Journal of Orthopaedic Research. 31: 1739-1744. PMID 23832376 DOI: 10.1002/jor.22432  1
2013 Crosby ND, Weisshaar CL, Winkelstein BA. Spinal neuronal plasticity is evident within 1 day after a painful cervical facet joint injury. Neuroscience Letters. 542: 102-6. PMID 23523644 DOI: 10.1016/j.neulet.2013.03.019  1
2013 Kras JV, Tanaka K, Gilliland TM, Winkelstein BA. An anatomical and immunohistochemical characterization of afferents innervating the C6-C7 facet joint after painful joint loading in the rat. Spine. 38: E325-31. PMID 23324931 DOI: 10.1097/BRS.0b013e318285b5bb  1
2013 Jaumard NV, Bauman JA, Guarino BB, Gokhale AJ, Lipschutz DE, Weisshaar CL, Welch WC, Winkelstein BA. ProDisc cervical arthroplasty does not alter facet joint contact pressure during lateral bending or axial torsion. Spine. 38: E84-93. PMID 23132537 DOI: 10.1097/BRS.0b013e31827b8a2d  1
2013 Dong L, Smith JR, Winkelstein BA. Ketorolac reduces spinal astrocytic activation and PAR1 expression associated with attenuation of pain after facet joint injury. Journal of Neurotrauma. 30: 818-25. PMID 23126437 DOI: 10.1089/neu.2012.2600  1
2013 Kras JV, Dong L, Winkelstein BA. The prostaglandin E2 receptor, EP2, is upregulated in the dorsal root ganglion after painful cervical facet joint injury in the rat. Spine. 38: 217-22. PMID 22789984 DOI: 10.1097/BRS.0b013e3182685ba1  1
2013 Jaumard NV, Baig HA, Guarino BB, Winkelstein BA. A three degree of freedom lumped parameter model of whole body vibration along the spine in the rat Asme 2013 Summer Bioengineering Conference, Sbc 2013. 1. DOI: 10.1115/SBC2013-14111  1
2013 Nicholson KJ, Gilliland TM, Winkelstein BA. Duration of nerve root compressive trauma modulates the subsequent thermal hyperalgesia and spinal expression of the glutamate transporter, GLT1 Asme 2013 Summer Bioengineering Conference, Sbc 2013. 1. DOI: 10.1115/SBC2013-14110  1
2013 Baig HA, Dorman DB, Shivers BL, Breaux-Waltz A, Chancey VC, Winkelstein BA. Characterization of the frequency and muscle response in the lumbar and thoracic spines during sinusoidal vertical whole body vibration Asme 2013 Summer Bioengineering Conference, Sbc 2013. 1. DOI: 10.1115/SBC2013-14055  1
2012 Bauman JA, Jaumard NV, Guarino BB, Weisshaar CL, Lipschutz DE, Welch WC, Winkelstein BA. Facet joint contact pressure is not significantly affected by ProDisc cervical disc arthroplasty in sagittal bending: A single-level cadaveric study Spine Journal. 12: 949-959. PMID 22975463 DOI: 10.1016/j.spinee.2012.08.013  1
2012 Lee DJ, Winkelstein BA. The failure response of the human cervical facet capsular ligament during facet joint retraction. Journal of Biomechanics. 45: 2325-9. PMID 22840489 DOI: 10.1016/j.jbiomech.2012.07.015  1
2012 Dong L, Quindlen JC, Lipschutz DE, Winkelstein BA. Whiplash-like facet joint loading initiates glutamatergic responses in the DRG and spinal cord associated with behavioral hypersensitivity. Brain Research. 1461: 51-63. PMID 22578356 DOI: 10.1016/j.brainres.2012.04.026  1
2012 Nicholson KJ, Guarino BB, Winkelstein BA. Transient nerve root compression load and duration differentially mediate behavioral sensitivity and associated spinal astrocyte activation and mGLuR5 expression Neuroscience. 209: 187-195. PMID 22387561 DOI: 10.1016/j.neuroscience.2012.02.027  1
2012 Crosby ND, Dong L, Winkelstein BA. Transient tensile facet capsular ligament loading above the mechanical threshold to induce pain also regulates spinal neuronal hyperexcitability Asme 2012 Summer Bioengineering Conference, Sbc 2012. 279-280. DOI: 10.1115/SBC2012-80592  1
2012 Weisshaar CL, Kras JV, Tanaka K, Winkelstein BA. Pain subsequent to mechanical loading of the facet capsular ligament depends on encoding by afferents in the spinal facet joint Asme 2012 Summer Bioengineering Conference, Sbc 2012. 653-654. DOI: 10.1115/SBC2012-80456  1
2012 Claeson AA, Yeh YJ, Akkin T, Winkelstein BA, Nuckley DJ, Barocas VH. OCT detects collagen fiber alignment in human cadaveric lumbar facet capsular ligament during mechanical loading Asme 2012 Summer Bioengineering Conference, Sbc 2012. 1285-1286. DOI: 10.1115/SBC2012-80296  1
2012 Gokhale AJ, Guarino BB, Winkelstein BA. The rat as a viable model for human cervical biomechanics: A quantitative anatomy study 2012 38th Annual Northeast Bioengineering Conference, Nebec 2012. 404-405. DOI: 10.1109/NEBC.2012.6207135  1
2012 Baig HA, Guarino BB, Jaumard NV, Winkelstein BA. The transmissibility response of the rat during whole body vibration along its long-axis 2012 38th Annual Northeast Bioengineering Conference, Nebec 2012. 402-403. DOI: 10.1109/NEBC.2012.6207134  1
2012 Guarino BB, Baig HA, Branconi JL, Winkelstein BA. Repeated whole-body vibration exposure induces prolonged mechanical hyperalgesia & increased spinal COX-2: A novel rat model 2012 38th Annual Northeast Bioengineering Conference, Nebec 2012. 400-401. DOI: 10.1109/NEBC.2012.6207133  1
2012 Freedman BR, Baig HA, Guarino BB, Winkelstein BA. Biomechanical effects of whole body vibration on spinal ligaments: A potential mechanism of tissue damage 2012 38th Annual Northeast Bioengineering Conference, Nebec 2012. 398-399. DOI: 10.1109/NEBC.2012.6207132  1
2012 Branconi JL, Guarino BB, Baig HA, Winkelstein BA. Painful whole body vibration increases NGF & BDNF in cervical intervertebral discs in the rat 2012 38th Annual Northeast Bioengineering Conference, Nebec 2012. 396-397. DOI: 10.1109/NEBC.2012.6207131  1
2011 Nicholson KJ, Quindlen JC, Winkelstein BA. Development of a duration threshold for modulating evoked neuronal responses after nerve root compression injury. Stapp Car Crash Journal. 55: 1-24. PMID 22869302  1
2011 Winkelstein BA. How can animal models inform on the transition to chronic symptoms in whiplash? Spine. 36: S218-25. PMID 22020616 DOI: 10.1097/BRS.0b013e3182387f96  1
2011 Curatolo M, Bogduk N, Ivancic PC, McLean SA, Siegmund GP, Winkelstein BA. The role of tissue damage in whiplash-associated disorders: discussion paper 1. Spine. 36: S309-15. PMID 22020601 DOI: 10.1097/BRS.0b013e318238842a  1
2011 Weisshaar CL, Winer JP, Guarino BB, Janmey PA, Winkelstein BA. The potential for salmon fibrin and thrombin to mitigate pain subsequent to cervical nerve root injury Biomaterials. 32: 9738-9746. PMID 21944723 DOI: 10.1016/j.biomaterials.2011.09.021  1
2011 Jaumard NV, Welch WC, Winkelstein BA. Spinal facet joint biomechanics and mechanotransduction in normal, injury and degenerative conditions. Journal of Biomechanical Engineering. 133: 071010. PMID 21823749 DOI: 10.1115/1.4004493  1
2011 Jaumard NV, Bauman JA, Weisshaar CL, Guarino BB, Welch WC, Winkelstein BA. Contact pressure in the facet joint during sagittal bending of the cadaveric cervical spine. Journal of Biomechanical Engineering. 133: 071004. PMID 21823743 DOI: 10.1115/1.4004409  0.64
2011 Dong L, Guarino BB, Jordan-Sciutto KL, Winkelstein BA. Activating transcription factor 4, a mediator of the integrated stress response, is increased in the dorsal root ganglia following painful facet joint distraction. Neuroscience. 193: 377-86. PMID 21821103 DOI: 10.1016/j.neuroscience.2011.07.059  1
2011 Chang YW, Winkelstein BA. Schwann cell proliferation and macrophage infiltration are evident at day 14 after painful cervical nerve root compression in the rat. Journal of Neurotrauma. 28: 2429-38. PMID 21787151 DOI: 10.1089/neu.2011.1918  1
2011 Quinn KP, Winkelstein BA. Preconditioning is correlated with altered collagen fiber alignment in ligament. Journal of Biomechanical Engineering. 133: 064506. PMID 21744935 DOI: 10.1115/1.4004205  1
2011 Quinn KP, Winkelstein BA. Detection of altered collagen fiber alignment in the cervical facet capsule after whiplash-like joint retraction. Annals of Biomedical Engineering. 39: 2163-73. PMID 21538155 DOI: 10.1007/s10439-011-0316-3  1
2011 Thorek DL, Weisshaar CL, Czupryna JC, Winkelstein BA, Tsourkas A. Superparamagnetic iron oxide-enhanced magnetic resonance imaging of neuroinflammation in a rat model of radicular pain. Molecular Imaging. 10: 206-14. PMID 21496449 DOI: 10.2310/7290.2010.00042  1
2011 Dunk NM, Nicholson KJ, Winkelstein BA. Impaired performance on the angle board test is induced in a model of painful whiplash injury but is only transient in a model of cervical radiculopathy. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 562-6. PMID 21337396 DOI: 10.1002/jor.21272  1
2011 Jaumard NV, Bauman JA, Welch WC, Winkelstein BA. Pressure measurement in the cervical spinal facet joint: considerations for maintaining joint anatomy and an intact capsule. Spine. 36: 1197-203. PMID 21224762 DOI: 10.1097/BRS.0b013e3181ee7de2  1
2011 Rothman SM, Ma LH, Whiteside GT, Winkelstein BA. Inflammatory cytokine and chemokine expression is differentially modulated acutely in the dorsal root ganglion in response to different nerve root compressions. Spine. 36: 197-202. PMID 20714281 DOI: 10.1097/BRS.0b013e3181ce4f4d  1
2011 Smith JR, Rothman SM, Janmey PA, Winkelstein BA. Spinal PAR1 RNA levels are regulated by mechanical & inflammatory cues in painful nerve root compression Asme 2011 Summer Bioengineering Conference, Sbc 2011. 983-984. DOI: 10.1115/SBC2011-53084  1
2011 Nicholson KJ, Winkelstein BA. The duration of a nerve root compression modulates evoked neuronal responses in a rat model of painful injury Asme 2011 Summer Bioengineering Conference, Sbc 2011. 75-76. DOI: 10.1115/SBC2011-53082  1
2011 Jaumard NV, Bauman JA, Weisshaar CL, Guarino BB, Welch WC, Winkelstein BA. Contact pressure in the facet joint during sagittal bending of the cadaveric cervical spine Journal of Biomechanical Engineering. 133. DOI: 10.1115/1.4004409  1
2010 Weisshaar CL, Dong L, Bowman AS, Perez FM, Guarino BB, Sweitzer SM, Winkelstein BA. Metabotropic glutamate receptor-5 and protein kinase C-epsilon increase in dorsal root ganglion neurons and spinal glial activation in an adolescent rat model of painful neck injury. Journal of Neurotrauma. 27: 2261-71. PMID 20925479 DOI: 10.1089/neu.2010.1460  1
2010 Quinn KP, Dong L, Golder FJ, Winkelstein BA. Neuronal hyperexcitability in the dorsal horn after painful facet joint injury. Pain. 151: 414-21. PMID 20739124 DOI: 10.1016/j.pain.2010.07.034  1
2010 Nicoll SB, Hee CK, Davis MB, Winkelstein BA. A rat model of temporomandibular joint pain with histopathologic modifications. Journal of Orofacial Pain. 24: 298-304. PMID 20664832  1
2010 Winkelstein BA, Kras JV. Is there an antinociceptive role for peripheral brain-derived neurotrophic factor? The Spine Journal : Official Journal of the North American Spine Society. 10: 733-5. PMID 20650413 DOI: 10.1016/j.spinee.2010.06.004  1
2010 Quinn KP, Winkelstein BA. Full field strain measurements of collagenous tissue by tracking fiber alignment through vector correlation. Journal of Biomechanics. 43: 2637-40. PMID 20494363 DOI: 10.1016/j.jbiomech.2010.05.008  1
2010 Quinn KP, Bauman JA, Crosby ND, Winkelstein BA. Anomalous fiber realignment during tensile loading of the rat facet capsular ligament identifies mechanically induced damage and physiological dysfunction. Journal of Biomechanics. 43: 1870-5. PMID 20381048 DOI: 10.1016/j.jbiomech.2010.03.032  1
2010 Rothman SM, Winkelstein BA. Cytokine antagonism reduces pain and modulates spinal astrocytic reactivity after cervical nerve root compression. Annals of Biomedical Engineering. 38: 2563-76. PMID 20309734 DOI: 10.1007/s10439-010-0012-8  1
2010 Rothman SM, Nicholson KJ, Winkelstein BA. Time-dependent mechanics and measures of glial activation and behavioral sensitivity in a rodent model of radiculopathy. Journal of Neurotrauma. 27: 803-14. PMID 20121422 DOI: 10.1089/neu.2009.1045  1
2010 Dong L, Winkelstein BA. Simulated whiplash modulates expression of the glutamatergic system in the spinal cord suggesting spinal plasticity is associated with painful dynamic cervical facet loading. Journal of Neurotrauma. 27: 163-74. PMID 19772459 DOI: 10.1089/neu.2009.0999  1
2010 Jaumard NV, Bauman JA, Welch WC, Winkelstein BA. Biomechanical comparison of contact pressure in the cervical facet joint during bending using a probe & pressure-sensitive paper Asme 2010 Summer Bioengineering Conference, Sbc 2010. 495-496. DOI: 10.1115/SBC2010-19498  1
2010 Sander EA, Quinn KP, Winkelstein BA, Barocas VH. Localizing damage in the cervical facet capsular ligament with imagebased mulitiscale models Asme 2010 Summer Bioengineering Conference, Sbc 2010. 469-470. DOI: 10.1115/SBC2010-19271  1
2010 Crosby ND, Quinn KP, Winkelstein BA. Microstructural modeling of fiber kinematics and biomechanics of the human facet capsular ligament during subfailure loading Asme 2010 Summer Bioengineering Conference, Sbc 2010. 709-710. DOI: 10.1115/SBC2010-19236  1
2009 Quinn KP, Winkelstein BA. Vector correlation technique for pixel-wise detection of collagen fiber realignment during injurious tensile loading. Journal of Biomedical Optics. 14: 054010. PMID 19895112 DOI: 10.1117/1.3227037  1
2009 Rothman SM, Guarino BB, Winkelstein BA. Spinal microglial proliferation is evident in a rat model of painful disc herniation both in the presence of behavioral hypersensitivity and following minocycline treatment sufficient to attenuate allodynia. Journal of Neuroscience Research. 87: 2709-17. PMID 19382225 DOI: 10.1002/jnr.22090  1
2009 Siegmund GP, Winkelstein BA, Ivancic PC, Svensson MY, Vasavada A. The anatomy and biomechanics of acute and chronic whiplash injury. Traffic Injury Prevention. 10: 101-12. PMID 19333822 DOI: 10.1080/15389580802593269  1
2009 Lee KE, Winkelstein BA. Joint distraction magnitude is associated with different behavioral outcomes and substance P levels for cervical facet joint loading in the rat. The Journal of Pain : Official Journal of the American Pain Society. 10: 436-45. PMID 19327645 DOI: 10.1016/j.jpain.2008.11.009  1
2009 Rothman SM, Huang Z, Lee KE, Weisshaar CL, Winkelstein BA. Cytokine mRNA expression in painful radiculopathy. The Journal of Pain : Official Journal of the American Pain Society. 10: 90-9. PMID 18848809 DOI: 10.1016/j.jpain.2008.07.008  1
2009 Hubbard RD, Martínez JJ, Burdick JA, Winkelstein BA. Controlled release of GDNF reduces nerve root-mediated behavioral hypersensitivity. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 27: 120-7. PMID 18634009 DOI: 10.1002/jor.20710  1
2009 Hirsch BE, Udupa JK, Siegler S, Winkelstein BA. The application of 3D image processing to studies of the musculoskeletal system Proceedings of Spie - the International Society For Optical Engineering. 7497. DOI: 10.1117/12.851181  1
2009 Craig KM, Quinn KP, Winkelstein BA. Force at damage and failure decreases with age in the human cadaveric facet capsular ligament during tension Proceedings of the Asme Summer Bioengineering Conference 2009, Sbc2009. 749-750. DOI: 10.1115/SBC2009-206135  1
2009 Quinn KP, Luck JF, Nightingale RW, Winkelstein BA. The onset of structural yield during tensile loading increases with age in the pediatric PMHS cervical spine Proceedings of the Asme Summer Bioengineering Conference 2009, Sbc2009. 217-218. DOI: 10.1115/SBC2009-204771  1
2009 Quinn KP, Lee KE, Winkelstein BA. Joint distractions sufficient to produce pain increase collagen fiber undulation in the cervical facet capsular ligament in the rat Proceedings of the Asme Summer Bioengineering Conference, Sbc2008. 919-920.  1
2009 Dong L, Odeleye AO, Akay C, Jordan-Sciutto KL, Winkelstein BA. The stress response in injured afferents of the capsular ligament depends on tensile loading applied to the facet joint Proceedings of the Asme Summer Bioengineering Conference, Sbc2008. 995-996.  1
2008 Hubbard RD, Quinn KP, Martínez JJ, Winkelstein BA. The role of graded nerve root compression on axonal damage, neuropeptide changes, and pain-related behaviors. Stapp Car Crash Journal. 52: 33-58. PMID 19085157  1
2008 Lee KE, Davis MB, Winkelstein BA. Capsular ligament involvement in the development of mechanical hyperalgesia after facet joint loading: behavioral and inflammatory outcomes in a rodent model of pain. Journal of Neurotrauma. 25: 1383-93. PMID 19061382 DOI: 10.1089/neu.2008.0700  1
2008 Quinn KP, Winkelstein BA. Altered collagen fiber kinematics define the onset of localized ligament damage during loading. Journal of Applied Physiology (Bethesda, Md. : 1985). 105: 1881-8. PMID 18845780 DOI: 10.1152/japplphysiol.90792.2008  1
2008 Liu J, Udupa JK, Saha PK, Odhner D, Hirsch BE, Siegler S, Simon S, Winkelstein BA. Rigid model-based 3D segmentation of the bones of joints in MR and CT images for motion analysis. Medical Physics. 35: 3637-49. PMID 18777924 DOI: 10.1118/1.2953567  1
2008 Dong L, Odeleye AO, Jordan-Sciutto KL, Winkelstein BA. Painful facet joint injury induces neuronal stress activation in the DRG: implications for cellular mechanisms of pain. Neuroscience Letters. 443: 90-4. PMID 18675314 DOI: 10.1016/j.neulet.2008.07.059  1
2008 Siegmund GP, Davis MB, Quinn KP, Hines E, Myers BS, Ejima S, Ono K, Kamiji K, Yasuki T, Winkelstein BA. Head-turned postures increase the risk of cervical facet capsule injury during whiplash. Spine. 33: 1643-9. PMID 18594456 DOI: 10.1097/BRS.0b013e31817b5bcf  1
2008 Hubbard RD, Winkelstein BA. Dorsal root compression produces myelinated axonal degeneration near the biomechanical thresholds for mechanical behavioral hypersensitivity. Experimental Neurology. 212: 482-9. PMID 18572166 DOI: 10.1016/j.expneurol.2008.04.042  1
2008 Winkelstein BA, Santos DG. An intact facet capsular ligament modulates behavioral sensitivity and spinal glial activation produced by cervical facet joint tension. Spine. 33: 856-62. PMID 18404104 DOI: 10.1097/BRS.0b013e31816b4710  1
2008 Hubbard RD, Chen Z, Winkelstein BA. Transient cervical nerve root compression modulates pain: load thresholds for allodynia and sustained changes in spinal neuropeptide expression. Journal of Biomechanics. 41: 677-85. PMID 17976629 DOI: 10.1016/j.jbiomech.2007.09.026  1
2007 Quinn KP, Lee KE, Ahaghotu CC, Winkelstein BA. Structural changes in the cervical facet capsular ligament: potential contributions to pain following subfailure loading. Stapp Car Crash Journal. 51: 169-87. PMID 18278597  1
2007 Rothman SM, Winkelstein BA. Chemical and mechanical nerve root insults induce differential behavioral sensitivity and glial activation that are enhanced in combination. Brain Research. 1181: 30-43. PMID 17920051 DOI: 10.1016/j.brainres.2007.08.064  1
2007 Quinn KP, Winkelstein BA. Cervical facet capsular ligament yield defines the threshold for injury and persistent joint-mediated neck pain. Journal of Biomechanics. 40: 2299-306. PMID 17141249 DOI: 10.1016/j.jbiomech.2006.10.015  1
2007 Lee KE, Winkelstein BA. Collagen fiber organization in the cervical facet capsular ligament following painful facet joint distraction in the rat Proceedings of the Asme Summer Bioengineering Conference 2007, Sbc 2007. 593-594.  1
2007 Dong L, Lee KE, Winkelstein BA. Dynamic distraction of the cervical facet joint produces higher mechanical allodynia than quasistatic distraction: Implications of displacement thresholds for pain in whiplash loading Proceedings of the Asme Summer Bioengineering Conference 2007, Sbc 2007. 609-610.  1
2007 Nicoll SB, Hee CK, Davis MB, Winkelstein BA. A rat model of osteoarthritic temporomandibular joint pain: Mechanically-induced behavioral hypersensitivity and histologic modifications Proceedings of the Asme Summer Bioengineering Conference 2007, Sbc 2007. 651-652.  1
2006 Lee KE, Franklin AN, Davis MB, Winkelstein BA. Tensile cervical facet capsule ligament mechanics: failure and subfailure responses in the rat. Journal of Biomechanics. 39: 1256-64. PMID 15899488 DOI: 10.1016/j.jbiomech.2005.03.018  1
2005 Rothman SM, Kreider RA, Winkelstein BA. Spinal neuropeptide responses in persistent and transient pain following cervical nerve root injury. Spine. 30: 2491-6. PMID 16284585 DOI: 10.1097/01.brs.0000186316.38111.4b  1
2005 Hubbard RD, Winkelstein BA. Transient cervical nerve root compression in the rat induces bilateral forepaw allodynia and spinal glial activation: mechanical factors in painful neck injuries. Spine. 30: 1924-32. PMID 16135981 DOI: 10.1097/01.brs.0000176239.72928.00  1
2005 Liu J, Udupa JK, Saha PK, Odhner D, Hirsch BE, Siegler S, Simon S, Winkelstein BA. Model-based 3D segmentation of the bones of joints in medical images Progress in Biomedical Optics and Imaging - Proceedings of Spie. 5747: 1793-1803. DOI: 10.1117/12.595425  1
2004 Lee KE, Davis MB, Mejilla RM, Winkelstein BA. In vivo cervical facet capsule distraction: mechanical implications for whiplash and neck pain. Stapp Car Crash Journal. 48: 373-95. PMID 17230274  0.76
2004 Lee KE, Thinnes JH, Gokhin DS, Winkelstein BA. A novel rodent neck pain model of facet-mediated behavioral hypersensitivity: implications for persistent pain and whiplash injury. Journal of Neuroscience Methods. 137: 151-9. PMID 15262055 DOI: 10.1016/j.jneumeth.2004.02.021  1
2004 Winkelstein BA, DeLeo JA. Mechanical thresholds for initiation and persistence of pain following nerve root injury: mechanical and chemical contributions at injury. Journal of Biomechanical Engineering. 126: 258-63. PMID 15179857 DOI: 10.1115/1.1695571  1
2004 Winkelstein BA. Mechanisms of central sensitization, neuroimmunology & injury biomechanics in persistent pain: implications for musculoskeletal disorders. Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology. 14: 87-93. PMID 14759754 DOI: 10.1016/j.jelekin.2003.09.017  1
2003 Winkelstein BA, Hubbard RD, DeLeo JA. Biomechanics and painful injuries: Tissue & CNS responses for nerve root mechanical injuries American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 55: 195-196. DOI: 10.1115/IMECE2003-43117  1
2003 Winkelstein BA. Changes in spontaneous behaviour in rats exposed to experimental disc herniation are produced by selective TNF-Alpha inhibition: Point of view Spine. 28: 1642. DOI: 10.1097/00007632-200308010-00003  1
2002 Winkelstein BA, DeLeo JA. Nerve root injury severity differentially modulates spinal glial activation in a rat lumbar radiculopathy model: considerations for persistent pain. Brain Research. 956: 294-301. PMID 12445698 DOI: 10.1016/S0006-8993(02)03560-6  1
2002 DeLeo JA, Winkelstein BA. Physiology of chronic spinal pain syndromes: from animal models to biomechanics. Spine. 27: 2526-37. PMID 12435988 DOI: 10.1097/01.BRS.0000032126.97065.FE  1
2002 Winkelstein BA, Myers BS. Importance of nonlinear and multivariable flexibility coefficients in the prediction of human cervical spine motion. Journal of Biomechanical Engineering. 124: 504-11. PMID 12405592 DOI: 10.1115/1.1504098  1
2002 Rutkowski MD, Winkelstein BA, Hickey WF, Pahl JL, DeLeo JA. Lumbar nerve root injury induces central nervous system neuroimmune activation and neuroinflammation in the rat: relationship to painful radiculopathy. Spine. 27: 1604-13. PMID 12163719 DOI: 10.1097/00007632-200208010-00003  1
2002 Nightingale RW, Winkelstein BA, Knaub KE, Richardson WJ, Luck JF, Myers BS. Comparative strengths and structural properties of the upper and lower cervical spine in flexion and extension. Journal of Biomechanics. 35: 725-32. PMID 12020991 DOI: 10.1016/S0021-9290(02)00037-4  1
2002 Winkelstein BA, Weinstein JN, DeLeo JA. The role of mechanical deformation in lumbar radiculopathy: an in vivo model. Spine. 27: 27-33. PMID 11805632 DOI: 10.1097/00007632-200201010-00009  1
2001 Siegmund GP, Myers BS, Davis MB, Bohnet HF, Winkelstein BA. Mechanical evidence of cervical facet capsule injury during whiplash: a cadaveric study using combined shear, compression, and extension loading. Spine. 26: 2095-101. PMID 11698885 DOI: 10.1097/00007632-200110010-00010  1
2001 Hunt JL, Winkelstein BA, Rutkowski MD, Weinstein JN, DeLeo JA. Repeated injury to the lumbar nerve roots produces enhanced mechanical allodynia and persistent spinal neuroinflammation. Spine. 26: 2073-9. PMID 11698881 DOI: 10.1097/00007632-200110010-00005  1
2001 Winkelstein BA, Rutkowski MD, Sweitzer SM, Pahl JL, DeLeo JA. Nerve injury proximal or distal to the DRG induces similar spinal glial activation and selective cytokine expression but differential behavioral responses to pharmacologic treatment. The Journal of Comparative Neurology. 439: 127-39. PMID 11596043 DOI: 10.1002/cne.2000  1
2001 Winkelstein BA, Rutkowski MD, Weinstein JN, DeLeo JA. Quantification of neural tissue injury in a rat radiculopathy model: comparison of local deformation, behavioral outcomes, and spinal cytokine mRNA for two surgeons. Journal of Neuroscience Methods. 111: 49-57. PMID 11574119  1
2001 Winkelstein BA, McLendon RE, Barbir A, Myers BS. An anatomical investigation of the human cervical facet capsule, quantifying muscle insertion area. Journal of Anatomy. 198: 455-61. PMID 11327207 DOI: 10.1017/S0021878201007518  1
2001 Winkelstein BA. Point of view Spine. 26: 944-945. DOI: 10.1097/00007632-200104150-00019  1
2000 Winkelstein BA, Nightingale RW, Richardson WJ, Myers BS. The cervical facet capsule and its role in whiplash injury: A biomechanical investigation Spine. 25: 1238-1246. PMID 10806500 DOI: 10.1097/00007632-200005150-00007  1
1999 Winkelstein BA, Richardson WJ, Myers BS. Mechanical investigation of the role of the cervical facet capsule in whiplash injury American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 42: 169-170.  1
1997 Winkelstein BA, Myers BS. The biomechanics of cervical spine injury and implications for injury prevention Medicine and Science in Sports and Exercise. 29: S246-S255. PMID 9247922  1
1997 Nightingale RW, McElhaney JH, Camacho DL, Kleinberger M, Winkelstein BA, Myers BS. The dynamic responses of the cervical spine: Buckling, end conditions, and tolerance in compressive impacts Sae Technical Papers. DOI: 10.4271/973344  1
1996 Myers BS, Winkelstein BA. Epidemiology, classification, mechanism, and tolerance of human cervical spine injuries Critical Reviews in Biomedical Engineering. 23: 307-409. PMID 9017344  1
1994 Meaney DF, Ross DT, Winkelstein BA, Brasko J, Goldstein D, Bilston LB, Thibault LE, Gennarelli TA. Modification of the cortical impact model to produce axonal injury in the rat cerebral cortex. Journal of Neurotrauma. 11: 599-612. PMID 7861451  1
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