☰

Carl T. Wittwer - Publications

Affiliations: 
Bioengineering University of Utah, Salt Lake City, UT 
Area:
Biomedical Engineering
Website:
https://healthcare.utah.edu/fad/mddetail.php?physicianID=u0029724
Tree Info Similar researchers PubMed Report error

157/235 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Huggett JF, Benes V, Bustin SA, Garson JA, Harris K, Kammel M, Kubista M, McHugh TD, Moran-Gilad J, Nolan T, Pfaffl MW, Salit M, Shipley G, Vallone PM, Vandesompele J, ... Wittwer C, et al. Cautionary note on contamination of reagents used for molecular detection of SARS-CoV-2. Clinical Chemistry. PMID 32894756 DOI: 10.1093/Clinchem/Hvaa214  0.353
2020 Ponnapalli SP, Bradley MW, Devine K, Bowen J, Coppens SE, Leraas KM, Milash BA, Li F, Luo H, Qiu S, Wu K, Yang H, Wittwer CT, Palmer CA, Jensen RL, et al. Retrospective clinical trial experimentally validates glioblastoma genome-wide pattern of DNA copy-number alterations predictor of survival. Apl Bioengineering. 4: 026106. PMID 32478280 DOI: 10.1063/1.5142559  0.65
2020 Rejali NA, Zuiter AM, Quackenbush JF, Wittwer CT. Reverse transcriptase kinetics for one-step RT-PCR. Analytical Biochemistry. 601: 113768. PMID 32416095 DOI: 10.1016/J.Ab.2020.113768  0.373
2019 Ruijter JM, Ruiz-Villalba A, van den Hoff AJJ, Gunst QD, Wittwer CT, van den Hoff MJB. Removal of artifact bias from qPCR results using DNA melting curve analysis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201901604R. PMID 31682470 DOI: 10.1096/Fj.201901604R  0.395
2019 Millington AL, Houskeeper JA, Quackenbush JF, Trauba JM, Wittwer CT. The kinetic requirements of extreme qPCR. Biomolecular Detection and Quantification. 17: 100081. PMID 31285997 DOI: 10.1016/J.Bdq.2019.100081  0.369
2018 Myrick JT, Pryor RJ, Palais RA, Ison SJ, Sanford L, Dwight ZL, Huuskonen JJ, Sundberg SO, Wittwer CT. Integrated Extreme Real-Time PCR and High-Speed Melting Analysis in 52 to 87 Seconds. Clinical Chemistry. PMID 30459167 DOI: 10.1373/Clinchem.2018.296608  0.413
2018 Andini N, Hu A, Zhou L, Cogill S, Wang TH, Wittwer CT, Yang S. A "Culture" Shift: Broad Bacterial Detection, Identification, and Antimicrobial Susceptibility Testing Directly from Whole Blood. Clinical Chemistry. PMID 30087140 DOI: 10.1373/Clinchem.2018.290189  0.31
2018 Rejali NA, Moric E, Wittwer CT. The Effect of Single Mismatches on Primer Extension. Clinical Chemistry. PMID 29444902 DOI: 10.1373/Clinchem.2017.282285  0.386
2017 Li M, Palais RA, Zhou L, Wittwer CT. Quantifying variant differences in DNA melting curves: Effects of length, melting rate, and curve overlay. Analytical Biochemistry. PMID 29061329 DOI: 10.1016/J.Ab.2017.10.015  0.425
2017 Pryor RJ, Myrick JT, Palais RA, Sundberg SO, Paek JY, Wittwer CT, Knight IT. High-speed Melting Analysis: The Effect of Melting Rate on Small Amplicon Microfluidic Genotyping. Clinical Chemistry. PMID 28818830 DOI: 10.1373/Clinchem.2017.276147  0.42
2017 Bustin SA, Wittwer CT. MIQE: A Step Toward More Robust and Reproducible Quantitative PCR. Clinical Chemistry. PMID 28606913 DOI: 10.1373/Clinchem.2016.268953  0.415
2017 Tashi T, Scott Reading N, Wuren T, Zhang X, Moore LG, Hu H, Tang F, Shestakova A, Lorenzo F, Burjanivova T, Koul P, Guchhait P, Wittwer CT, Julian CG, Shah B, et al. Gain-of-function EGLN1 prolyl hydroxylase (PHD2 D4E:C127S) in combination with EPAS1 (HIF-2α) polymorphism lowers hemoglobin concentration in Tibetan highlanders. Journal of Molecular Medicine (Berlin, Germany). PMID 28233034 DOI: 10.1007/S00109-017-1519-3  0.585
2017 Wittwer CT. Democratizing the Real-Time PCR. Clinical Chemistry. PMID 28159801 DOI: 10.1373/Clinchem.2016.263269  0.387
2017 Trauba JM, Wittwer CT. Microfluidic Extreme PCR: <1 Minute DNA Amplification in a Thin Film Disposable Journal of Biomedical Science and Engineering. 10: 219-231. DOI: 10.4236/Jbise.2017.105017  0.365
2016 Wittwer CT. Portable Nanopore Sequencing for Viral Surveillance. Clinical Chemistry. PMID 27638016 DOI: 10.1373/Clinchem.2016.256693  0.353
2015 Zhou L, Palais RA, Paxton CN, Geiersbach KB, Wittwer CT. Copy number assessment by competitive PCR with limiting deoxynucleotide triphosphates and high-resolution melting. Clinical Chemistry. 61: 724-33. PMID 25759466 DOI: 10.1373/Clinchem.2014.236208  0.342
2015 Chiu RW, Lo YM, Wittwer CT. Molecular diagnostics: a revolution in progress. Clinical Chemistry. 61: 1-3. PMID 25550473 DOI: 10.1373/Clinchem.2014.233361  0.342
2015 Farrar JS, Wittwer CT. Extreme PCR: efficient and specific DNA amplification in 15-60 seconds. Clinical Chemistry. 61: 145-53. PMID 25320377 DOI: 10.1373/Clinchem.2014.228304  0.397
2015 Tashi T, Reading NS, Shestakova A, Burjanivova T, Uran T, Lorenzo V FR, Hu H, Huff C, Moore L, Koul P, Wittwer CT, Gordeuk VR, Ge R, Prchal JT. Tibetan Gain-of-Function Variant of Prolyl Hydroxylase 2 (EGLN1) and Selected SNPs of HIF-2-Alpha (EPAS1) Are Associated with Lower Hemoglobin Values in Tibetans Blood. 126: 3332-3332. DOI: 10.1182/Blood.V126.23.3332.3332  0.607
2015 Zhou L, Palais B, Wittwer C. Abstract 4923: Detecting copy number variation using dNTP limited PCR and high-resolution melting Cancer Research. 75: 4923-4923. DOI: 10.1158/1538-7445.Am2015-4923  0.396
2014 Sundberg SO, Wittwer CT, Howell RM, Huuskonen J, Pryor RJ, Farrar JS, Stiles HM, Palais RA, Knight IT. Microfluidic genotyping by rapid serial PCR and high-speed melting analysis. Clinical Chemistry. 60: 1306-13. PMID 25117377 DOI: 10.1373/Clinchem.2014.223768  0.357
2014 Sundberg SO, Wittwer CT, Zhou L, Palais R, Dwight Z, Gale BK. Quasi-digital PCR: Enrichment and quantification of rare DNA variants. Biomedical Microdevices. 16: 639-44. PMID 24781884 DOI: 10.1007/S10544-014-9866-0  0.435
2014 Li M, Zhou L, Palais RA, Wittwer CT. Genotyping accuracy of high-resolution DNA melting instruments. Clinical Chemistry. 60: 864-72. PMID 24718912 DOI: 10.1373/Clinchem.2013.220160  0.413
2014 Montgomery JL, Rejali N, Wittwer CT. The influence of nucleotide sequence and temperature on the activity of thermostable DNA polymerases. The Journal of Molecular Diagnostics : Jmd. 16: 305-13. PMID 24607271 DOI: 10.1016/J.Jmoldx.2014.01.006  0.653
2014 Dwight ZL, Palais R, Kent J, Wittwer CT. Heterozygote PCR product melting curve prediction. Human Mutation. 35: 278-82. PMID 24375593 DOI: 10.1002/Humu.22494  0.342
2014 Sanford LN, Wittwer CT. Fluorescence-based temperature control for polymerase chain reaction. Analytical Biochemistry. 448: 75-81. PMID 24291705 DOI: 10.1016/J.Ab.2013.11.027  0.359
2014 Montgomery JL, Wittwer CT. Influence of PCR reagents on DNA polymerase extension rates measured on real-time PCR instruments. Clinical Chemistry. 60: 334-40. PMID 24081987 DOI: 10.1373/Clinchem.2013.212829  0.685
2014 Shestakova A, Lorenzo F, Tashi T, Lanikova L, Wittwer CT, Prchal JT. Tibetan PHD2D4E High Altitude Adapted Gene Can be Rapidly Detected By High Resolution Melting Assay Blood. 124: 4875-4875. DOI: 10.1182/Blood.V124.21.4875.4875  0.674
2013 Wittwer CT, Herrmann MG, Moss AA, Rasmussen RP. Continuous fluorescence monitoring of rapid cycle DNA amplification. 1997. Biotechniques. 54: 314-20. PMID 23905170 DOI: 10.2144/000114043  0.356
2013 Montgomery JL, Rejali N, Wittwer CT. Stopped-flow DNA polymerase assay by continuous monitoring of dNTP incorporation by fluorescence. Analytical Biochemistry. 441: 133-9. PMID 23872003 DOI: 10.1016/J.Ab.2013.07.008  0.659
2013 Illson ML, Dempsey-Nunez L, Kent J, Huang Q, Brebner A, Raff ML, Watkins D, Gilfix BM, Wittwer CT, Rosenblatt DS. High resolution melting analysis of the MMAB gene in cblB patients and in those with undiagnosed methylmalonic aciduria. Molecular Genetics and Metabolism. 110: 86-9. PMID 23707710 DOI: 10.1016/J.Ymgme.2013.04.020  0.315
2013 Huggett JF, Foy CA, Benes V, Emslie K, Garson JA, Haynes R, Hellemans J, Kubista M, Mueller RD, Nolan T, Pfaffl MW, Shipley GL, Vandesompele J, Wittwer CT, Bustin SA. The digital MIQE guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments. Clinical Chemistry. 59: 892-902. PMID 23570709 DOI: 10.1373/Clinchem.2013.206375  0.302
2013 Zhou L, Palais RA, Ye F, Chen J, Montgomery JL, Wittwer CT. Symmetric snapback primers for scanning and genotyping of the cystic fibrosis transmembrane conductance regulator gene. Clinical Chemistry. 59: 1052-61. PMID 23503723 DOI: 10.1373/Clinchem.2013.202689  0.689
2013 Sanford LN, Wittwer CT. Monitoring temperature with fluorescence during real-time PCR and melting analysis. Analytical Biochemistry. 434: 26-33. PMID 23142429 DOI: 10.1016/J.Ab.2012.10.037  0.341
2012 Dempsey-Nunez L, Illson ML, Kent J, Huang Q, Brebner A, Watkins D, Gilfix BM, Wittwer CT, Rosenblatt DS. High resolution melting analysis of the MMAA gene in patients with cblA and in those with undiagnosed methylmalonic aciduria. Molecular Genetics and Metabolism. 107: 363-7. PMID 23026888 DOI: 10.1016/J.Ymgme.2012.09.012  0.323
2012 Dwight ZL, Palais R, Wittwer CT. uAnalyze: web-based high-resolution DNA melting analysis with comparison to thermodynamic predictions. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 9: 1805-11. PMID 22889837 DOI: 10.1109/Tcbb.2012.112  0.379
2012 Stasia MJ, van Leeuwen K, de Boer M, Martel C, Mollin M, Thuret I, Michel G, Hanson C, Augustine NH, Coutton C, Satre V, Wittwer CT, Hill H, Roos D. Rare duplication or deletion of exons 6, 7 and 8 in CYBB leading to X-linked chronic granulomatous disease in two patients from different families. Journal of Clinical Immunology. 32: 653-62. PMID 22382877 DOI: 10.1007/S10875-012-9667-2  0.3
2011 Smith GD, Zhou L, Rowe LR, Jarboe EA, Collins BT, Bentz JS, Wittwer CT, Chadwick BE. Allele-specific PCR with competitive probe blocking for sensitive and specific detection of BRAF V600E in thyroid fine-needle aspiration specimens. Acta Cytologica. 55: 576-83. PMID 22156469 DOI: 10.1159/000333453  0.326
2011 von Ahsen N, Wittwer CT, Schütz E. Monovalent and divalent salt correction algorithms for Tm prediction--recommendations for Primer3 usage. Briefings in Bioinformatics. 12: 514-7. PMID 21949267 DOI: 10.1093/Bib/Bbq081  0.302
2011 von Kanel T, Gerber D, Wittwer CT, Hermann M, Gallati S. Detecting and resolving position-dependent temperature effects in real-time quantitative polymerase chain reaction. Analytical Biochemistry. 419: 161-7. PMID 21925477 DOI: 10.1016/J.Ab.2011.08.041  0.363
2011 Farrar JS, Palais RA, Wittwer CT. Snapback primer genotyping of the Gilbert syndrome UGT1A1 (TA)(n) promoter polymorphism by high-resolution melting. Clinical Chemistry. 57: 1303-10. PMID 21771946 DOI: 10.1373/Clinchem.2011.166306  0.334
2011 Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley GL, Vandesompele J, Wittwer CT. Primer sequence disclosure: a clarification of the MIQE guidelines. Clinical Chemistry. 57: 919-21. PMID 21421813 DOI: 10.1373/Clinchem.2011.162958  0.322
2011 Dwight Z, Palais R, Wittwer CT. uMELT: prediction of high-resolution melting curves and dynamic melting profiles of PCR products in a rich web application. Bioinformatics (Oxford, England). 27: 1019-20. PMID 21300699 DOI: 10.1093/Bioinformatics/Btr065  0.34
2011 Seipp MT, Wittwer CT. Detecting rare thrombophilia variants by high-resolution melting. Clinical Chemistry. 57: 639-41. PMID 21292852 DOI: 10.1373/Clinchem.2010.159160  0.423
2011 Zhou L, Wang Y, Wittwer CT. Rare allele enrichment and detection by allele-specific PCR, competitive probe blocking, and melting analysis Biotechniques. 50: 311-318. DOI: 10.2144/000114510  0.395
2011 Zhou L, Wittwer C. Abstract A23: Rare allele enrichment by DNA melting analysis Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-A23  0.476
2010 Seipp MT, Herrmann M, Wittwer CT. Automated DNA extraction, quantification, dilution, and PCR preparation for genotyping by high-resolution melting. Journal of Biomolecular Techniques : Jbt. 21: 163-6. PMID 21119928  0.343
2010 Liew M, Wittwer CT, Voelkerding KV. Nucleotide extension genotyping by high-resolution melting. The Journal of Molecular Diagnostics. 12: 731-738. PMID 20847280 DOI: 10.2353/Jmoldx.2010.090149  0.399
2010 Wittwer CT. Making DNA melting useful. Clinical Chemistry. 56: 1500-1. PMID 20581082 DOI: 10.1373/Clinchem.2010.146175  0.435
2010 Zhou L, Palais RA, Smith GD, Anderson D, Rowe LR, Wittwer CT. Enrichment and detection of rare alleles by means of snapback primers and rapid-cycle PCR. Clinical Chemistry. 56: 814-22. PMID 20299678 DOI: 10.1373/Clinchem.2009.142034  0.373
2010 Hill HR, Augustine NH, Pryor RJ, Reed GH, Bagnato JD, Tebo AE, Bender JM, Pasi BM, Chinen J, Hanson IC, de Boer M, Roos D, Wittwer CT. Rapid genetic analysis of x-linked chronic granulomatous disease by high-resolution melting. The Journal of Molecular Diagnostics : Jmd. 12: 368-76. PMID 20228266 DOI: 10.2353/Jmoldx.2010.090147  0.401
2010 Montgomery JL, Sanford LN, Wittwer CT. High-resolution DNA melting analysis in clinical research and diagnostics. Expert Review of Molecular Diagnostics. 10: 219-40. PMID 20214540 DOI: 10.1586/Erm.09.84  0.676
2010 Kumánovics A, Wittwer CT, Pryor RJ, Augustine NH, Leppert MF, Carey JC, Ochs HD, Wedgwood RJ, Faville RJ, Quie PG, Hill HR. Rapid molecular analysis of the STAT3 gene in Job syndrome of hyper-IgE and recurrent infectious diseases. The Journal of Molecular Diagnostics : Jmd. 12: 213-9. PMID 20093388 DOI: 10.2353/Jmoldx.2010.090080  0.354
2010 Erali M, Wittwer CT. High resolution melting analysis for gene scanning. Methods (San Diego, Calif.). 50: 250-61. PMID 20085814 DOI: 10.1016/J.Ymeth.2010.01.013  0.463
2010 Sundberg SO, Wittwer CT, Gao C, Gale BK. Spinning disk platform for microfluidic digital polymerase chain reaction. Analytical Chemistry. 82: 1546-50. PMID 20085301 DOI: 10.1021/Ac902398C  0.363
2010 Zhou L, Smith D, Wittwer C. Abstract 2118: Rare allele enrichment by ARMS combined with probe base genotyping techniques Cancer Research. 70: 2118-2118. DOI: 10.1158/1538-7445.Am10-2118  0.402
2010 McKinney JT, Nay LM, De Koeyer D, Reed GH, Wall M, Palais RA, Jarret RL, Wittwer CT. Mutation Scanning and Genotyping in Plants by High-Resolution DNA Melting The Handbook of Plant Mutation Screening: Mining of Natural and Induced Alleles. 149-165. DOI: 10.1002/9783527629398.ch9  0.366
2009 Parant JM, George SA, Pryor R, Wittwer CT, Yost HJ. A rapid and efficient method of genotyping zebrafish mutants. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 3168-74. PMID 19890916 DOI: 10.1002/Dvdy.22143  0.349
2009 Margraf RL, Calderon FR, Mao R, Wittwer CT. RET mutation scanning update: exon 15. Clinical Chemistry. 55: 2059-61. PMID 19745057 DOI: 10.1373/Clinchem.2009.132209  0.388
2009 Seipp MT, Durtschi JD, Voelkerding KV, Wittwer CT. Multiplex amplicon genotyping by high-resolution melting. Journal of Biomolecular Techniques : Jbt. 20: 160-4. PMID 19568454  0.331
2009 Wittwer CT. High-resolution DNA melting analysis: advancements and limitations. Human Mutation. 30: 857-9. PMID 19479960 DOI: 10.1002/Humu.20951  0.478
2009 Crews N, Wittwer CT, Montgomery J, Pryor R, Gale B. Spatial DNA melting analysis for genotyping and variant scanning. Analytical Chemistry. 81: 2053-8. PMID 19228012 DOI: 10.1021/Ac801495W  0.693
2009 Palais R, Wittwer CT. Mathematical algorithms for high-resolution DNA melting analysis. Methods in Enzymology. 454: 323-43. PMID 19216933 DOI: 10.1016/S0076-6879(08)03813-5  0.438
2009 Lyon E, Wittwer CT. LightCycler technology in molecular diagnostics. The Journal of Molecular Diagnostics : Jmd. 11: 93-101. PMID 19196999 DOI: 10.2353/Jmoldx.2009.080094  0.409
2009 Farrar JS, Reed GH, Wittwer CT. High-Resolution Melting Curve Analysis for Molecular Diagnostics Molecular Diagnostics: Second Edition. 229-245. DOI: 10.1016/B978-0-12-374537-8.00015-8  0.345
2008 Erali M, Palais R, Wittwer C. SNP genotyping by unlabeled probe melting analysis. Methods in Molecular Biology (Clifton, N.J.). 429: 199-206. PMID 18695968 DOI: 10.1007/978-1-60327-040-3_14  0.456
2008 Zhou L, Errigo RJ, Lu H, Poritz MA, Seipp MT, Wittwer CT. Snapback primer genotyping with saturating DNA dye and melting analysis. Clinical Chemistry. 54: 1648-56. PMID 18676584 DOI: 10.1373/Clinchem.2008.107615  0.409
2008 Erali M, Voelkerding KV, Wittwer CT. High resolution melting applications for clinical laboratory medicine. Experimental and Molecular Pathology. 85: 50-8. PMID 18502416 DOI: 10.1016/J.Yexmp.2008.03.012  0.48
2008 Crews N, Wittwer C, Palais R, Gale B. Product differentiation during continuous-flow thermal gradient PCR. Lab On a Chip. 8: 919-24. PMID 18497912 DOI: 10.1039/B716437H  0.422
2008 Elenitoba-Johnson O, David D, Crews N, Wittwer CT. Plastic versus glass capillaries for rapid-cycle PCR. Biotechniques. 44: 487-8, 490, 492. PMID 18476813 DOI: 10.2144/000112722  0.354
2008 Gundry CN, Dobrowolski SF, Martin YR, Robbins TC, Nay LM, Boyd N, Coyne T, Wall MD, Wittwer CT, Teng DH. Base-pair neutral homozygotes can be discriminated by calibrated high-resolution melting of small amplicons. Nucleic Acids Research. 36: 3401-8. PMID 18448472 DOI: 10.1093/Nar/Gkn204  0.306
2008 Margraf RL, Mao R, Wittwer CT. Rapid diagnosis of MEN2B using unlabeled probe melting analysis and the LightCycler 480 instrument. The Journal of Molecular Diagnostics : Jmd. 10: 123-8. PMID 18258924 DOI: 10.2353/Jmoldx.2008.070111  0.416
2008 Seipp MT, Pattison D, Durtschi JD, Jama M, Voelkerding KV, Wittwer CT. Quadruplex genotyping of F5, F2, and MTHFR variants in a single closed tube by high-resolution amplicon melting. Clinical Chemistry. 54: 108-15. PMID 17981920 DOI: 10.1373/Clinchem.2007.097121  0.404
2008 Crews N, Wittwer C, Gale B. Continuous-flow thermal gradient PCR. Biomedical Microdevices. 10: 187-95. PMID 17874300 DOI: 10.1007/S10544-007-9124-9  0.355
2007 Montgomery J, Wittwer CT, Kent JO, Zhou L. Scanning the cystic fibrosis transmembrane conductance regulator gene using high-resolution DNA melting analysis. Clinical Chemistry. 53: 1891-8. PMID 17890437 DOI: 10.1373/Clinchem.2007.092361  0.652
2007 Dames S, Pattison DC, Bromley LK, Wittwer CT, Voelkerding KV. Unlabeled probes for the detection and typing of herpes simplex virus. Clinical Chemistry. 53: 1847-54. PMID 17720894 DOI: 10.1373/Clinchem.2007.090761  0.398
2007 Poulson MD, Wittwer CT. Closed-tube genotyping of apolipoprotein E by isolated-probe PCR with multiple unlabeled probes and high-resolution DNA melting analysis. Biotechniques. 43: 87-91. PMID 17695257 DOI: 10.2144/000112459  0.464
2007 Dames S, Margraf RL, Pattison DC, Wittwer CT, Voelkerding KV. Characterization of aberrant melting peaks in unlabeled probe assays. The Journal of Molecular Diagnostics : Jmd. 9: 290-6. PMID 17591927 DOI: 10.2353/Jmoldx.2007.060139  0.416
2007 Seipp MT, Durtschi JD, Liew MA, Williams J, Damjanovich K, Pont-Kingdon G, Lyon E, Voelkerding KV, Wittwer CT. Unlabeled oligonucleotides as internal temperature controls for genotyping by amplicon melting. The Journal of Molecular Diagnostics : Jmd. 9: 284-9. PMID 17591926 DOI: 10.2353/Jmoldx.2007.060136  0.419
2007 Reed GH, Kent JO, Wittwer CT. High-resolution DNA melting analysis for simple and efficient molecular diagnostics. Pharmacogenomics. 8: 597-608. PMID 17559349 DOI: 10.2217/14622416.8.6.597  0.474
2007 Herrmann MG, Durtschi JD, Wittwer CT, Voelkerding KV. Expanded instrument comparison of amplicon DNA melting analysis for mutation scanning and genotyping. Clinical Chemistry. 53: 1544-8. PMID 17556647 DOI: 10.1373/Clinchem.2007.088120  0.402
2007 Vandersteen JG, Bayrak-Toydemir P, Palais RA, Wittwer CT. Identifying common genetic variants by high-resolution melting. Clinical Chemistry. 53: 1191-8. PMID 17525106 DOI: 10.1373/Clinchem.2007.085407  0.319
2007 Montgomery J, Wittwer CT, Palais R, Zhou L. Simultaneous mutation scanning and genotyping by high-resolution DNA melting analysis. Nature Protocols. 2: 59-66. PMID 17401339 DOI: 10.1038/Nprot.2007.10  0.716
2007 Margraf RL, Mao R, Highsmith WE, Holtegaard LM, Wittwer CT. RET proto-oncogene genotyping using unlabeled probes, the masking technique, and amplicon high-resolution melting analysis. The Journal of Molecular Diagnostics : Jmd. 9: 184-96. PMID 17384210 DOI: 10.2353/Jmoldx.2007.060091  0.447
2007 Liew M, Seipp M, Durtschi J, Margraf RL, Dames S, Erali M, Voelkerding K, Wittwer C. Closed-tube SNP genotyping without labeled probes/a comparison between unlabeled probe and amplicon melting. American Journal of Clinical Pathology. 127: 341-8. PMID 17276934 DOI: 10.1309/N7Rarxh3623Avkdv  0.419
2007 Herrmann MG, Durtschi JD, Bromley LK, Wittwer CT, Voelkerding KV. Instrument comparison for heterozygote scanning of single and double heterozygotes: a correction and extension of Herrmann et al., Clin Chem 2006;52:494-503. Clinical Chemistry. 53: 150-2. PMID 17202505 DOI: 10.1373/Clinchem.2006.081240  0.358
2007 Sundberg SO, Wittwer CT, Greer J, Pryor RJ, Elenitoba-Johnson O, Gale BK. Solution-phase DNA mutation scanning and SNP genotyping by nanoliter melting analysis. Biomedical Microdevices. 9: 159-66. PMID 17165128 DOI: 10.1007/S10544-006-9017-3  0.482
2007 Greer J, Sundberg SO, Wittwer CT, Gale BK. Comparison of glass etching to xurography prototyping of microfluidic channels for DNA melting analysis Journal of Micromechanics and Microengineering. 17: 2407-2413. DOI: 10.1088/0960-1317/17/12/003  0.371
2007 Zhou L, Lu H, Myers A, Taylor M, Fuller T, Eccles D, Wittwer C. 31-OR: HLA matching by high-resolution DNA melting analysis for living related transplantation Human Immunology. 68: S116. DOI: 10.1016/J.Humimm.2007.08.224  0.322
2006 Pryor RJ, Wittwer CT. Real-time polymerase chain reaction and melting curve analysis. Methods in Molecular Biology (Clifton, N.J.). 336: 19-32. PMID 16916250 DOI: 10.1385/1-59745-074-X:19  0.445
2006 Erali M, Pounder JI, Woods GL, Petti CA, Wittwer CT. Multiplex single-color PCR with amplicon melting analysis for identification of Aspergillus species. Clinical Chemistry. 52: 1443-5. PMID 16798978 DOI: 10.1373/Clinchem.2006.068510  0.376
2006 Liew M, Nelson L, Margraf R, Mitchell S, Erali M, Mao R, Lyon E, Wittwer C. Genotyping of human platelet antigens 1 to 6 and 15 by high-resolution amplicon melting and conventional hybridization probes. The Journal of Molecular Diagnostics : Jmd. 8: 97-104. PMID 16436640 DOI: 10.2353/Jmoldx.2006.050053  0.418
2006 Herrmann MG, Durtschi JD, Bromley LK, Wittwer CT, Voelkerding KV. Amplicon DNA melting analysis for mutation scanning and genotyping: cross-platform comparison of instruments and dyes. Clinical Chemistry. 52: 494-503. PMID 16423901 DOI: 10.1373/Clinchem.2005.063438  0.428
2006 Margraf RL, Mao R, Wittwer CT. Masking selected sequence variation by incorporating mismatches into melting analysis probes. Human Mutation. 27: 269-78. PMID 16411177 DOI: 10.1002/Humu.20290  0.409
2006 Margraf RL, Mao R, Highsmith WE, Holtegaard LM, Wittwer CT. Mutation scanning of the RET protooncogene using high-resolution melting analysis. Clinical Chemistry. 52: 138-41. PMID 16391329 DOI: 10.1373/Clinchem.2005.052951  0.316
2006 Herrmann MG, Durtschi JD, Voelkerding KV, Wittwer CT. Instrument Comparison for DNA Genotyping by Amplicon Melting Jala - Journal of the Association For Laboratory Automation. 11: 273-277. DOI: 10.1016/J.Jala.2006.04.003  0.463
2005 Chou LS, Meadows C, Wittwer CT, Lyon E. Unlabeled oligonucleotide probes modified with locked nucleic acids for improved mismatch discrimination in genotyping by melting analysis. Biotechniques. 39: 644, 646, 648 passim. PMID 16312213 DOI: 10.2144/000112050  0.382
2005 Chou LS, Lyon E, Wittwer CT. A comparison of high-resolution melting analysis with denaturing high-performance liquid chromatography for mutation scanning: cystic fibrosis transmembrane conductance regulator gene as a model. American Journal of Clinical Pathology. 124: 330-8. PMID 16191501 DOI: 10.1309/Bf3M-Ljn8-J527-Mwqy  0.403
2005 Zhou L, Wang L, Palais R, Pryor R, Wittwer CT. High-resolution DNA melting analysis for simultaneous mutation scanning and genotyping in solution. Clinical Chemistry. 51: 1770-7. PMID 16189378 DOI: 10.1373/Clinchem.2005.054924  0.443
2005 Palais RA, Liew MA, Wittwer CT. Quantitative heteroduplex analysis for single nucleotide polymorphism genotyping. Analytical Biochemistry. 346: 167-75. PMID 16188219 DOI: 10.1016/J.Ab.2005.08.010  0.456
2005 Graham R, Liew M, Meadows C, Lyon E, Wittwer CT. Distinguishing different DNA heterozygotes by high-resolution melting. Clinical Chemistry. 51: 1295-8. PMID 15905310 DOI: 10.1373/Clinchem.2005.051516  0.463
2005 Odell ID, Cloud JL, Seipp M, Wittwer CT. Rapid species identification within the Mycobacterium chelonae-abscessus group by high-resolution melting analysis of hsp65 PCR products. American Journal of Clinical Pathology. 123: 96-101. PMID 15762284 DOI: 10.1309/Wdr082X9Ffjbqqgb  0.347
2005 Gingeras TR, Higuchi R, Kricka LJ, Lo YM, Wittwer CT. Fifty years of molecular (DNA/RNA) diagnostics. Clinical Chemistry. 51: 661-71. PMID 15650028 DOI: 10.1373/Clinchem.2004.045336  0.356
2005 Seipp MT, Erali M, Wies RL, Wittwer C. HLA-B27 typing: evaluation of an allele-specific PCR melting assay and two flow cytometric antigen assays. Cytometry Part B-Clinical Cytometry. 63: 10-15. PMID 15624199 DOI: 10.1002/Cyto.B.20039  0.346
2005 Wittwer CT. DNA from A to Z. Daniel H. Farkas. Washington, DC: AACC Press, 2004, 144 pp., $25.00 ($20.00 AACC members), softcover. ISBN 1-59425-002-2. Clinical Chemistry. 51: 1320-1321. DOI: 10.1373/Clinchem.2004.040535  0.341
2005 Chou L, Lyon E, Wittwer CT. A Comparison of High-Resolution Melting Analysis With Denaturing High-Performance Liquid Chromatography for Mutation Scanning American Journal of Clinical Pathology. 124: 330-338. DOI: 10.1309/Bf3Mljn8J527Mwqy  0.402
2004 Margraf RL, Erali M, Liew M, Wittwer CT. Genotyping hepatitis C virus by heteroduplex mobility analysis using temperature gradient capillary electrophoresis. Journal of Clinical Microbiology. 42: 4545-51. PMID 15472307 DOI: 10.1128/Jcm.42.10.4545-4551.2004  0.309
2004 Willmore C, Holden JA, Zhou L, Tripp S, Wittwer CT, Layfield LJ. Detection of c-kit-activating mutations in gastrointestinal stromal tumors by high-resolution amplicon melting analysis. American Journal of Clinical Pathology. 122: 206-16. PMID 15323137 DOI: 10.1309/4E6Uyby62N2Fca6N  0.381
2004 Margraf RL, Page S, Erali M, Wittwer CT. Single-tube method for nucleic acid extraction, amplification, purification, and sequencing. Clinical Chemistry. 50: 1755-61. PMID 15308595 DOI: 10.1373/Clinchem.2004.035808  0.302
2004 Reed GH, Wittwer CT. Sensitivity and specificity of single-nucleotide polymorphism scanning by high-resolution melting analysis. Clinical Chemistry. 50: 1748-54. PMID 15308590 DOI: 10.1373/Clinchem.2003.029751  0.404
2004 Zhou L, Vandersteen J, Wang L, Fuller T, Taylor M, Palais B, Wittwer CT. High-resolution DNA melting curve analysis to establish HLA genotypic identity Tissue Antigens. 64: 156-164. PMID 15245370 DOI: 10.1111/J.1399-0039.2004.00248.X  0.412
2004 Liew M, Pryor R, Palais R, Meadows C, Erali M, Lyon E, Wittwer C. Genotyping of single-nucleotide polymorphisms by high-resolution melting of small amplicons. Clinical Chemistry. 50: 1156-64. PMID 15229148 DOI: 10.1373/Clinchem.2004.032136  0.427
2004 Zhou L, Myers AN, Vandersteen JG, Wang L, Wittwer CT. Closed-tube genotyping with unlabeled oligonucleotide probes and a saturating DNA dye. Clinical Chemistry. 50: 1328-35. PMID 15166111 DOI: 10.1373/Clinchem.2004.034322  0.442
2004 Liew M, Erali M, Page S, Hillyard D, Wittwer C. Hepatitis C genotyping by denaturing high-performance liquid chromatography. Journal of Clinical Microbiology. 42: 158-63. PMID 14715747 DOI: 10.1128/Jcm.42.1.158-163.2004  0.325
2004 Herrmann MG, Dobrowolski SF, Wittwer CT. Erratum: Rapid β-globin genotyping by multiplexing probe melting temperature and color (Clinical Chemistry (2000) 46 (425-428)) Clinical Chemistry. 50. DOI: 10.1373/Clinchem.2004.033985  0.317
2003 Millson A, Suli A, Hartung L, Kunitake S, Bennett A, Nordberg MC, Hanna W, Wittwer CT, Seth A, Lyon E. Comparison of two quantitative polymerase chain reaction methods for detecting HER2/neu amplification. The Journal of Molecular Diagnostics : Jmd. 5: 184-90. PMID 12876209 DOI: 10.1016/S1525-1578(10)60471-0  0.366
2003 Wittwer CT, Reed GH, Gundry CN, Vandersteen JG, Pryor RJ. High-resolution genotyping by amplicon melting analysis using LCGreen. Clinical Chemistry. 49: 853-60. PMID 12765979 DOI: 10.1373/49.6.853  0.381
2003 Erali M, Schmidt B, Lyon E, Wittwer C. Evaluation of Electronic Microarrays for Genotyping Factor V, Factor II, and MTHFR Clinical Chemistry. 49: 732-739. PMID 12709363 DOI: 10.1373/49.5.732  0.368
2003 Gundry CN, Vandersteen JG, Reed GH, Pryor RJ, Chen J, Wittwer CT. Amplicon melting analysis with labeled primers: a closed-tube method for differentiating homozygotes and heterozygotes. Clinical Chemistry. 49: 396-406. PMID 12600951 DOI: 10.1373/49.3.396  0.401
2003 Wittwer CT. RT-PCR Protocols. Methods in Molecular Biology, Vol. 193. Joe O’Connell, ed. Totowa, NJ: Humana Press, 2002, 378 pp., $99.50, hardcover. ISBN 0-89603-875-0. Clinical Chemistry. 49: 345-345. DOI: 10.1373/49.2.345  0.319
2002 Millward H, Samowitz W, Wittwer CT, Bernard PS. Homogeneous amplification and mutation scanning of the p53 gene using fluorescent melting curves. Clinical Chemistry. 48: 1321-8. PMID 12142390 DOI: 10.1093/Clinchem/48.8.1321  0.302
2001 Wittwer CT, Herrmann MG, Gundry CN, Elenitoba-Johnson KSJ. Real-time multiplex PCR assays Methods. 25: 430-442. PMID 11846612 DOI: 10.1006/Meth.2001.1265  0.382
2001 Lyon E, Millson A, Lowery MC, Woods R, Wittwer CT. Quantification of HER2/neu gene amplification by competitive PCR using fluorescent melting curve analysis Clinical Chemistry. 47: 844-851. PMID 11325887 DOI: 10.1093/Clinchem/47.5.844  0.421
2001 Crockett AO, Wittwer CT. Fluorescein-labeled oligonucleotides for real-time PCR: Using the inherent quenching of deoxyguanosine nucleotides Analytical Biochemistry. 290: 89-97. PMID 11180941 DOI: 10.1006/Abio.2000.4957  0.39
2001 Elenitoba-Johnson KSJ, Bohling SD, Wittwer CT, King TC. Multiplex PCR by multicolor fluorimetry and fluorescence melting curve analysis Nature Medicine. 7: 249-253. PMID 11175859 DOI: 10.1038/84708  0.358
2001 Heap DM, Herrmann MG, Wittwer CT. PCR amplification using electrolytic resistance for heating and temperature monitoring. Biotechniques. 29: 1006-12. PMID 11084862 DOI: 10.2144/00295St01  0.312
2000 Millson AS, Spangler FL, Wittwer CT, Lyon E. Comparison of automated short tandem repeat and manual variable number of tandem repeat analysis of chimerism in bone marrow transplant patients Diagnostic Molecular Pathology. 9: 91-97. PMID 10850545 DOI: 10.1097/00019606-200006000-00005  0.402
2000 De Silva D, Wittwer CT. Monitoring hybridization during polymerase chain reaction Journal of Chromatography B: Biomedical Sciences and Applications. 741: 3-13. PMID 10839126 DOI: 10.1016/S0378-4347(00)00055-4  0.46
2000 Herrmann MG, Dobrowolski SF, Wittwer CT. Rapid β-globin genotyping by multiplexing probe melting temperature and color Clinical Chemistry. 46: 425-428. PMID 10702535 DOI: 10.1093/Clinchem/46.3.425  0.414
2000 Bernard PS, Wittwer CT. Homogeneous amplification and variant detection by fluorescent hybridization probes Clinical Chemistry. 46: 147-148. PMID 10657368 DOI: 10.1093/Clinchem/46.2.147  0.44
1999 Gundry CN, Bernard PS, Herrmann MG, Reed GH, Wittwer CT. Rapid F508del and F508C assay using fluorescent hybridization probes Genetic Testing. 3: 365-370. PMID 10627945 DOI: 10.1089/Gte.1999.3.365  0.412
1999 Bernard PS, Pritham GH, Wittwer CT. Color multiplexing hybridization probes using the apolipoprotein E locus as a model system for genotyping Analytical Biochemistry. 273: 221-228. PMID 10469493 DOI: 10.1006/Abio.1999.4217  0.394
1999 Hussey CE, Lyon E, Millson A, Lay MJ, Wittwer CT, Segal GH. A rapid practical RT-PCR-based approach for the detection of the PML/RARalpha fusion transcript in acute promyelocytic leukemia American Journal of Clinical Pathology. 112: 256-262. PMID 10439807 DOI: 10.1093/Ajcp/112.2.256  0.354
1999 Bohling SD, Wittwer CT, King TC, Elenitoba-Johnson KSJ. Fluorescence melting curve analysis for the detection of the bcl-1/JH translocation in mantle cell lymphoma Laboratory Investigation. 79: 337-345. PMID 10092070  0.305
1999 Bohling SD, King TC, Wittwer CT, Elenitoba-Johnson KSJ. Rapid simultaneous amplification and detection of the MBR/JH chromosomal translocation by fluorescence melting curve analysis American Journal of Pathology. 154: 97-103. PMID 9916923 DOI: 10.1016/S0002-9440(10)65255-8  0.421
1998 Bernard PS, Ajioka RS, Kushner JP, Wittwer CT. Homogeneous multiplex genotyping of hemochromatosis mutations with fluorescent hybridization probes American Journal of Pathology. 153: 1055-1061. PMID 9777937 DOI: 10.1016/S0002-9440(10)65650-7  0.406
1998 Bernard PS, Lay MJ, Wittwer CT. Integrated amplification and detection of the C677T point mutation in the methylenetetrahydrofolate reductase gene by fluorescence resonance energy transfer and probe melting curves Analytical Biochemistry. 255: 101-107. PMID 9448847 DOI: 10.1006/Abio.1997.2427  0.426
1998 Lyon E, Millson A, Phan T, Wittwer CT. Detection and identification of base alterations within the region of factor V leiden by fluorescent melting curves Molecular Diagnosis. 3: 203-210. DOI: 10.1016/S1084-8592(98)80041-6  0.373
1997 Lay MJ, Wittwer CT. Real-time fluorescence genotyping of factor V leiden during rapid-cycle PCR Clinical Chemistry. 43: 2262-2267. PMID 9439442 DOI: 10.1093/Clinchem/43.12.2262  0.397
1997 Mouritsen CL, Wittwer CT, Reed G, Khan TM, Martins TB, Jaskowski TD, Litwin CM, Hill HR. Detection of Epstein-Barr viral DNA in serum using rapid-cycle PCR Biochemical and Molecular Medicine. 60: 161-168. PMID 9169098 DOI: 10.1006/Bmme.1997.2571  0.332
1997 Swerdlow H, Jones BJ, Wittwer CT. Fully automated DNA reaction and analysis in a fluidic capillary instrument. Analytical Chemistry. 69: 848-55. PMID 9068272 DOI: 10.1021/Ac961104O  0.37
1997 Ririe KM, Rasmussen RP, Wittwer CT. Product differentiation by analysis of DNA melting curves during the polymerase chain reaction Analytical Biochemistry. 245: 154-160. PMID 9056205 DOI: 10.1006/Abio.1996.9916  0.408
1997 Wittwer CT, Ririe KM, Andrew RV, David DA, Gundry RA, Balis UJ. The LightCycler(TM): A microvolume multisample fluorimeter with rapid temperature control Biotechniques. 22: 176-181. PMID 8994665 DOI: 10.2144/97221Pf02  0.374
1996 Mouritsen CL, Wittwer CT, Litwin CM, Yang L, Weis JJ, Martins TB, Jaskowski TD, Hill HR. Polymerase chain reaction detection of Lyme disease: Correlation with clinical manifestations and serologic responses American Journal of Clinical Pathology. 105: 647-654. PMID 8623775 DOI: 10.1093/Ajcp/105.5.647  0.37
1995 Adleberg JM, Wittwer C. Use of the polymerase chain reaction in the diagnosis of ocular disease. Current Opinion in Ophthalmology. 6: 80-85. PMID 10150875 DOI: 10.1097/00055735-199506000-00014  0.303
1995 Lim LC, Segal GH, Wittwer CT. Detection of bcl-1 gene rearrangement and B-cell clonality in mantle cell lymphoma using formalin-fixed, paraffin-embedded tissues American Journal of Clinical Pathology. 104: 689-695. PMID 8526214 DOI: 10.1093/Ajcp/104.6.689  0.315
1993 Albro J, Bauer KD, Hitchcock CL, Wittwer CT. Improved DNA content histograms from formalin-fixed, paraffin-embedded liver tissue by proteinase K digestion Cytometry. 14: 673-678. PMID 8404374 DOI: 10.1002/Cyto.990140612  0.325
1993 Wittwer CT, Marshall BC, Reed GH, Cherry JL. Rapid cycle allele-specific amplification: studies with the cystic fibrosis delta F508 locus. Clinical Chemistry. 39: 804-809. DOI: 10.1093/Clinchem/39.5.804  0.378
1992 Hopfenbeck JA, Holden JA, Wittwer CT, Kjeldsberg CR. Digoxigenin-labeled probes amplified from genomic DNA detect T-cell gene rearrangements American Journal of Clinical Pathology. 97: 638-644. PMID 1315485 DOI: 10.1093/Ajcp/97.5.638  0.408
1990 Wittwer CT, Beck S, Peterson M, Davidson R, Wilson DE, Hansen RG. Mild pantothenate deficiency in rats elevates serum triglyceride and free fatty acid levels. The Journal of Nutrition. 120: 719-25. PMID 2366105 DOI: 10.1093/Jn/120.7.719  0.484
1990 Wittwer CT, Fillmore GC, Garling DJ. Minimizing the time required for DNA amplification by efficient heat transfer to small samples Analytical Biochemistry. 186: 328-331. PMID 2363506 DOI: 10.1016/0003-2697(90)90090-V  0.377
1989 Wittwer CT, Schweitzer C, Pearson J, Song WO, Windham CT, Wyse BW, Hansen RG. Enzymes for liberation of pantothenic acid in blood: use of plasma pantetheinase. The American Journal of Clinical Nutrition. 50: 1072-8. PMID 2816792 DOI: 10.1093/Ajcn/50.5.1072  0.489
1987 Wittwer CT, Graves CP, Peterson MA, Jorgensen E, Wilson DE, Thoene JG, Wyse BW, Windham CT, Hansen RG. Pantethine lipomodulation: evidence for cysteamine mediation in vitro and in vivo. Atherosclerosis. 68: 41-9. PMID 3689482 DOI: 10.1016/0021-9150(87)90092-X  0.49
1986 Wittwer CT, Wyse BW, Hansen RG. Enzymatic hydrolysis of pantetheine. Methods in Enzymology. 122: 36-43. PMID 3517567  0.422
1983 Wittwer CT, Burkhard D, Ririe K, Rasmussen R, Brown J, Wyse BW, Hansen RG. Purification and properties of a pantetheine-hydrolyzing enzyme from pig kidney. The Journal of Biological Chemistry. 258: 9733-8. PMID 6885768  0.449
1982 Wittwer C, Wyse B, Hansen RG. Assay of the enzymatic hydrolysis of pantetheine. Analytical Biochemistry. 122: 213-22. PMID 7114442 DOI: 10.1016/0003-2697(82)90273-1  0.534
1979 Wyse BW, Wittwer C, Hansen RG. Radioimmunoassay for pantothenic acid in blood and other tissues. Clinical Chemistry. 25: 108-10. PMID 761345 DOI: 10.1093/Clinchem/25.1.108  0.489
Low-probability matches (unlikely to be authored by this person)
1992 Weis JH, Tan SS, Martin BK, Wittwer CT. Detection of rare mRNAs via quantitative RT-PCR Trends in Genetics. 8: 263-264. PMID 1509514 DOI: 10.1016/0168-9525(92)90242-V  0.3
2008 Lim HY, Farley M, Wittwer C, Parker C. Characteristics of Laboratory Screening Suggest That Paroxysmal Nocturnal Hemoglobinuria (PNH) Is Perceived Primarily as a Bone Marrow Failure Syndrome Rather Than as a Hemolytic Anemia Blood. 112: 4107-4107. DOI: 10.1182/Blood.V112.11.4107.4107  0.295
1994 Molot RJ, Meeker TC, Wittwer CT, Perkins SL, Segal GH, Masih AS, Braylan RC, Kjeldsberg CR. Antigen expression and polymerase chain reaction amplification of mantle cell lymphomas Blood. 83: 1626-1631. PMID 8123854 DOI: 10.1182/Blood.V83.6.1626.1626  0.295
2009 Margraf RL, Crockett DK, Krautscheid PM, Seamons R, Calderon FR, Wittwer CT, Mao R. Multiple endocrine neoplasia type 2 RET protooncogene database: repository of MEN2-associated RET sequence variation and reference for genotype/phenotype correlations. Human Mutation. 30: 548-56. PMID 19177457 DOI: 10.1002/Humu.20928  0.292
2008 Crews N, Ameel T, Wittwer C, Gale B. Flow-induced thermal effects on spatial DNA melting. Lab On a Chip. 8: 1922-9. PMID 18941694 DOI: 10.1039/B807034B  0.29
2023 Wittwer CT. Rapid Cycle and Extreme Polymerase Chain Reaction. Methods in Molecular Biology (Clifton, N.J.). 2621: 257-266. PMID 37041449 DOI: 10.1007/978-1-0716-2950-5_14  0.288
2007 Sundberg SO, Greer J, Wittwer CT, Gale BK. Miniaturization of warfarin metabolism genotyping by melting analysis using asymmetric PCR and unlabeled oligonucleotide probes Aiche Annual Meeting, Conference Proceedings.  0.288
2006 Willmore-Payne C, Holden JA, Zhou H, Gupta D, Hirschowitz S, Wittwer CT, Layfield LJ. Evaluation of Her-2/neu gene status in osteosarcoma by fluorescence in situ hybridization and multiplex and monoplex polymerase chain reactions. Archives of Pathology & Laboratory Medicine. 130: 691-8. PMID 16683887 DOI: 10.1043/1543-2165(2006)130[691:Eongsi]2.0.Co;2  0.288
2009 Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley GL, Vandesompele J, Wittwer CT. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clinical Chemistry. 55: 611-22. PMID 19246619 DOI: 10.1373/Clinchem.2008.112797  0.286
2006 Frei-Lahr D, Inoue N, Wittwer C, Herrmann M, Babcock W, Kinoshita T, Parker CJ. Molecular Complete Remission of Clonal Hematopoiesis in Paroxysmal Nocturnal Hemoglobinuria (PNH) after Syngeneic Transplantation. Blood. 108: 5362-5362. DOI: 10.1182/Blood.V108.11.5362.5362  0.285
2007 Liew M, Groll MC, Thompson JE, Call SL, Moser JE, Hoopes JD, Voelkerding K, Wittwer C, Spendlove RS. Validating a custom multiplex ELISA against individual commercial immunoassays using clinical samples. Biotechniques. 42: 327-8, 330-3. PMID 17390539 DOI: 10.2144/000112332  0.284
1990 Holden JA, Rolfson DH, Wittwer CT. Human DNA topoisomerase II: Evaluation of enzyme activity in normal and neoplastic tissues Biochemistry®. 2127-2134. PMID 2158345 DOI: 10.1021/Bi00460A024  0.282
1998 Pritham GH, Wittwer CT. Continuous fluorescent monitoring of rapid cycle polymerase chain reaction Journal of Clinical Ligand Assay. 21: 404-412.  0.275
1989 Wittwer CT, Fillmore GC, Hillyard DR. Automated polymerase chain reaction in capillary tubes with hot air Nucleic Acids Research. 17: 4353-4357. PMID 2740218 DOI: 10.1093/Nar/17.11.4353  0.275
2015 Rifai N, Topol E, Chan E, Lo YM, Wittwer CT. Disruptive Innovation in Laboratory Medicine. Clinical Chemistry. 61: 1129-32. PMID 26152753 DOI: 10.1373/Clinchem.2015.243667  0.274
2015 Liew M, Mao R, Wittwer CT, Salama ME. Detection of chromosomal translocations in formalin-fixed paraffin-embedded (FFPE) leukemic specimens by digital expression profiling. International Journal of Laboratory Hematology. 37: 690-8. PMID 26037935 DOI: 10.1111/Ijlh.12388  0.274
2013 Bustin SA, Benes V, Garson J, Hellemans J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley G, Wittwer CT, Schjerling P, Day PJ, Abreu M, Aguado B, et al. The need for transparency and good practices in the qPCR literature. Nature Methods. 10: 1063-7. PMID 24173381 DOI: 10.1038/Nmeth.2697  0.273
2001 Von Ahsen N, Wittwer CT, Schütz E. Oligonucleotide melting temperatures under PCR conditions: Nearest-neighbor corrections for MG2+, deoxynucleotide triphosphate, and dimethyl sulfoxide concentrations with comparison to alternative empirical formulas Clinical Chemistry. 47: 1956-1961. PMID 11673362 DOI: 10.1093/Clinchem/47.11.1956  0.271
2006 Mochizuki K, Sugimori C, Feng X, Lu X, Reed GH, Wittwer CT, Nakao S. Small Populations of PNH-Type Cells in Aplastic Anemia Patients Are Derived from PIG-A Mutant Stem Cell Clones without Proliferative Advantage. Blood. 108: 974-974. DOI: 10.1182/Blood.V108.11.974.974  0.269
1993 Wittwer CT, Marshall BC, Reed GH, Cherry JL. Rapid cycle allele-specific amplification: Studies with the cystic fibrosis ΔF508 locus Clinical Chemistry. 39: 804-809. PMID 7683581  0.268
1990 Song WO, Smith A, Wittwer C, Wyse B, Hansen G. Determination of plasma pantothenic acid by indirect enzyme linked immunosorbent assay Nutrition Research. 10: 439-448. DOI: 10.1016/S0271-5317(05)80671-2  0.265
2005 Inoue N, Izui T, Murakmai Y, Endo Y, Nishimura J, Kanakura Y, Meyers G, Wittwer C, Chen Z, Babcock W, Frei-Lahr D, Parker C, Kinoshita T. Clonal Expansion in Paroxysmal Nocturnal Hemoglobinuria (PNH): Expression of Mutant HMGA2 Suggests That PNH Is a Benign Tumor of the Bone Marrow. Blood. 106: 3533-3533. DOI: 10.1182/Blood.V106.11.3533.3533  0.265
2006 Inoue N, Izui-Sarumaru T, Murakami Y, Endo Y, Nishimura JI, Kurokawa K, Kuwayama M, Shime H, Machii T, Kanakura Y, Meyers G, Wittwer C, Chen Z, Babcock W, Frei-Lahr D, et al. Molecular basis of clonal expansion of hematopoiesis in 2 patients with paroxysmal nocturnal hemoglobinuria (PNH). Blood. 108: 4232-4236. PMID 16940417 DOI: 10.1182/Blood-2006-05-025148  0.262
1990 Rabkin MS, Wittwer CT, Soong VY. Flow cytometric DNA content analysis of a case of pilomatrix carcinoma showing multiple recurrences and invasion of the cranial vault Journal of the American Academy of Dermatology. 23: 104-108. PMID 2365860 DOI: 10.1016/0190-9622(90)70193-L  0.262
1995 Lingenfelter B, Fuller TC, Hartung L, Hunter J, Wittwer C. HLA-B27 screening by flow cytometry Communications in Clinical Cytometry. 22: 146-149. PMID 7587746 DOI: 10.1002/Cyto.990220211  0.257
1998 Morrison TB, Weis JJ, Wittwer CT. Quantification of lowcopy transcripts by continuous SYBR® green I monitoring during amplification Biotechniques. 24: 954-962. PMID 9631186  0.254
1992 Segal GH, Wittwer CT, Fishleder AJ, Stoler MH, Tubbs RR, Kjeldsberg CR. Identification of monoclonal B-cell populations by rapid cycle polymerase chain reaction: A practical screening method for the detection of immunoglobulin gene rearrangements American Journal of Pathology. 141: 1291-1297. PMID 1466395  0.253
2010 Borowitz MJ, Craig FE, Digiuseppe JA, Illingworth AJ, Rosse W, Sutherland DR, Wittwer CT, Richards SJ. Guidelines for the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria and related disorders by flow cytometry. Cytometry. Part B, Clinical Cytometry. 78: 211-30. PMID 20533382 DOI: 10.1002/Cyto.B.20525  0.253
1996 Segal GH, Hussey CE, Wittwer CT. PCR for T-cell rearrangements Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B. 5: 297-298. PMID 8955623 DOI: 10.1097/00019606-199612000-00012  0.252
2000 Brown M, Wittwer C. Flow Cytometry: Principles and Clinical Applications in Hematology Clinical Chemistry. 46: 1221-1229. DOI: 10.1093/Clinchem/46.8.1221  0.252
2009 Bender JM, Rand TH, Ampofo K, Pavia AT, Schober M, Tebo A, Pasi B, Augustine NH, Pryor RJ, Wittwer CT, Hill HR. Family clusters of variant X-linked chronic granulomatous disease. The Pediatric Infectious Disease Journal. 28: 529-33. PMID 19483518 DOI: 10.1097/Inf.0B013E318194Cf09  0.251
1985 Wittwer CT, Gahl WA, Butler JD, Zatz M, Thoene JG. Metabolism of pantethine in cystinosis. The Journal of Clinical Investigation. 76: 1665-72. PMID 4056044 DOI: 10.1172/Jci112152  0.25
2002 Bernard PS, Wittwer CT. Real-time PCR technology for cancer diagnostics. Clinical Chemistry. 48: 1178-85. PMID 12142370 DOI: 10.1093/Clinchem/48.8.1178  0.245
1990 Hammond EH, Wittwer CT, Greenwood J, Knape WA, Yowell RL, Menlove RL, Craven C, Renlund DG, Bristow MR, Dewitt CW, O’connell JB. Relationship of OKT3 sensitization and vascular rejection in cardiac transplant patients receiving OKT3 rejection prophylaxis Transplantation. 50: 776-782. PMID 2122559 DOI: 10.1097/00007890-199011000-00008  0.245
2009 Erali M, Pattison DC, Wittwer CT, Petti CA. Human papillomavirus genotyping using an automated film-based chip array. The Journal of Molecular Diagnostics : Jmd. 11: 439-45. PMID 19644025 DOI: 10.2353/Jmoldx.2009.080154  0.241
2016 Geiersbach KB, Willmore-Payne C, Pasi AV, Paxton CN, Werner TL, Xu X, Wittwer CT, Gulbahce HE, Downs-Kelly E. Genomic Copy Number Analysis of HER2-Equivocal Breast Cancers. American Journal of Clinical Pathology. PMID 27614666 DOI: 10.1093/Ajcp/Aqw130  0.237
2013 Sanford LN, Kent JO, Wittwer CT. Quantum method for fluorescence background removal in DNA melting analysis. Analytical Chemistry. 85: 9907-15. PMID 24070125 DOI: 10.1021/ac4024928  0.232
1996 Florell SR, Townsend JJ, Klatt EC, Pysher TJ, Coffin CM, Wittwer CT, Viskochil DH. Aprosencephaly and cerebellar dysgenesis in sibs. American Journal of Medical Genetics. 63: 542-8. PMID 8826432 DOI: 10.1002/(Sici)1096-8628(19960628)63:4<542::Aid-Ajmg6>3.0.Co;2-Q  0.231
1993 Hammond EA, Yowell RL, Greenwood J, Hartung L, Renlund D, Wittwer C. Prevention of adverse clinical outcome by monitoring of cardiac transplant patients for murine monoclonal CD3 antibody (OKT3) sensitization Transplantation. 55: 1061-1063. PMID 8497882 DOI: 10.1097/00007890-199305000-00022  0.229
1996 Endo M, Beatty PG, Vreeke TM, Wittwer CT, Singh SP, Parker CJ. Syngeneic bone marrow transplantation without conditioning in a patient with paroxysmal nocturnal hemoglobinuria: In vivo evidence that the mutant stem cells have a survival advantage Blood. 88: 742-750. PMID 8695823 DOI: 10.1182/Blood.V88.2.742.Bloodjournal882742  0.228
2006 Sundberg SO, Greer J, Wittwer CT, Pryor RJ, Elenitoba-Johnson O, Gale BK. Homogeneous DNA melting analysis for mutation scanning using nanoliter volumes Micro Total Analysis Systems - Proceedings of Microtas 2006 Conference: 10th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 1441-1443.  0.226
2012 Rifai N, Diamandis EP, Lo YM, Kricka LJ, Wilding P, Ladenson JH, Wittwer CT. Advancing laboratory medicine through innovation: a tale of six inventors. Clinical Chemistry. 58: 502-10. PMID 22238255 DOI: 10.1373/Clinchem.2011.178582  0.226
1991 Wittwer CT, Garling DJ. Rapid cycle DNA amplification: Time and temperature optimization Biotechniques. 10. PMID 2003928  0.226
1992 Kershisnik MM, Knisely AS, Sun CC, Andrews JM, Wittwer CT. Cytomegalovirus infection, fetal liver disease, and neonatal hemochromatosis. Human Pathology. 23: 1075-80. PMID 1325409 DOI: 10.1016/0046-8177(92)90272-5  0.225
1985 Wittwer CT, Thoene JG. 876 METABOLISM OF PANTETHINE IN NEPHROPATHIC CYSTINOSIS Pediatric Research. 19: 256A-256A. DOI: 10.1203/00006450-198504000-00906  0.224
2019 Ravkov EV, Charlton CM, Barker AP, Hill H, Peterson LK, Slev P, Tebo A, Voelkerding KV, Wittwer CT, Heikal N, Delgado JC, Lázár-Molnár E, Kumánovics A. Evaluation of Mass Cytometry in the Clinical Laboratory. Cytometry. Part B, Clinical Cytometry. PMID 31173473 DOI: 10.1002/Cyto.B.21791  0.224
1984 Wittwer CT, Thoene JG. PHARMACOLOGY OF PANTETHINE IN NEPHROPATHIC CYSTINOSIS Pediatric Research. 18: 163A-163A. DOI: 10.1203/00006450-198404001-00419  0.22
2015 Liew M, Farley M, Andreasen J, Parker CJ, Wittwer CT. Rare event counting of CD59- red cells in human blood: A 47-month experience using PNH consensus guidelines for WBC and RBC testing in a reference lab. Cytometry. Part B, Clinical Cytometry. 88: 261-9. PMID 25605539 DOI: 10.1002/Cyto.B.21225  0.219
1990 O'Connell JB, Greenwood JH, Bristow MR, Hammond EH, Wittwer CT, Yowell RL, Renlund DG. Sensitization to OKT3: Increased frequency with prolonged administration Journal of the American College of Cardiology. 15: A69. DOI: 10.1016/0735-1097(90)91993-5  0.213
2008 Willmore-Payne C, Holden JA, Wittwer CT, Layfield LJ. The use of EGFR exon 19 and 21 unlabeled DNA probes to screen for activating mutations in non-small cell lung cancer. Journal of Biomolecular Techniques : Jbt. 19: 217-24. PMID 19137110  0.212
2009 Lo YM, Wittwer CT. Molecular diagnostics: at the cutting edge of translational research. Clinical Chemistry. 55: 601. PMID 19325016 DOI: 10.1373/Clinchem.2008.119586  0.211
2003 García-Villalba P, Denkers ND, Wittwer CT, Hoff C, Nelson RD, Mauch TJ. Real-time PCR quantification of AT1 and AT2 angiotensin receptor mRNA expression in the developing rat kidney. Nephron. Experimental Nephrology. 94: e154-9. PMID 12972714 DOI: 10.1159/000072499  0.209
2009 Wittwer CT, Rasmussen RP, Ririe KM. Rapid polymerase chain reaction and melting analysis The Pcr Revolution: Basic Technologies and Applications. 48-69. DOI: 10.1017/CBO9780511818974.006  0.204
2019 Dennis Lo YM, Baudhuin LM, Pantel K, Chiu RWK, Nolte FS, Wittwer CT. Molecular Diagnostics: Going from Strength to Strength Clinical Chemistry. 66: 1-2. DOI: 10.1093/Clinchem.2019.314385  0.201
1999 Wang R, Nuttall KL, Fenn JP, Wittwer CT. Fuzzy set identification of bone marrow cells Journal of Shanghai University (English Edition). 3: 70-73. DOI: 10.1007/S11741-999-0033-4  0.2
2011 Chadwick BE, Singh RS, Wang HH, Bibbo M, Cibas ES, Zhou L, Rowe LR, Jarboe EA, Collins BT, Bentz JS, Wittwer CT, Smith GD, Clark DP, Erozan YS, Luu MH, et al. Contents Vol. 55, 2011 Acta Cytologica. 55. DOI: 10.1159/000334348  0.198
2003 Wilson HM, Kluth DC, Miner JH, García-Villalba P, Denkers ND, Wittwer CT, Hoff C, Nelson RD, Mauch TJ, Ikebe M, Nonoguchi H, Nakayama Y, Tashima Y, Shimada K, Tanzawa K, et al. Contents Vol. 94, 2003 Nephron Experimental Nephrology. 94. DOI: 10.1159/000073460  0.198
1986 Hansen RG, Windham CT, Wittwer CT, Wyse BW. Placing The Role Of Meat In Human Nutrition In Perspective Journal of Animal Science. 62: 7-15. DOI: 10.2527/1986.62Supplement_17S  0.192
1988 Pearson SD, Wittwer CT, Owen Ash K. Evaluation of three commercial kits for the confirmation of antibodies to human immunodeficiency virus (HIV-1) Clinical Chemistry. 34: 1930. PMID 3166415 DOI: 10.1093/Clinchem/34.9.1930  0.191
2010 Hill HR, Wittwer CT. Reply Pediatric Infectious Disease Journal. 29: 191. DOI: 10.1097/01.Inf.0000368378.02858.F0  0.191
1986 Wittwer CT, Gahl WA, Butler JD, Zatz M, Thoene JG. Metabolism of Pantethine in Cystinosis Nutrition in Clinical Practice. 1: 59-60. DOI: 10.1177/088453368600100121  0.182
2021 Rejali NA, Ye FD, Zuiter AM, Keller CC, Wittwer CT. Nearest-neighbour transition-state analysis for nucleic acid kinetics. Nucleic Acids Research. PMID 33823552 DOI: 10.1093/nar/gkab205  0.179
2011 Chadwick BE, Singh RS, Wang HH, Bibbo M, Cibas ES, Zhou L, Rowe LR, Jarboe EA, Collins BT, Bentz JS, Wittwer CT, Smith GD, Clark DP, Erozan YS, Luu MH, et al. Subject Index Vol. 55, 2011 Acta Cytologica. 55: 597-598. DOI: 10.1159/000334347  0.177
1988 Rabkin MS, Wittwer CT, Kjeldsberg CR, Piepkorn MW. Flow-cytometric DNA content of histiocytosis X (Langerhans cell histiocytosis) American Journal of Pathology. 131: 283-289. PMID 3258734  0.175
2005 Lewis TB, Robison JE, Bastien R, Milash B, Boucher K, Samlowski WE, Leachman SA, Dirk Noyes R, Wittwer CT, Perreard L, Bernard PS. Molecular classification of melanoma using real-time quantitative reverse transcriptase-polymerase chain reaction. Cancer. 104: 1678-86. PMID 16116595 DOI: 10.1002/cncr.21372  0.17
1988 Rabkin MS, Kjeldsberg CR, Hammond ME, Wittwer CT, Nathwani B. Clinical, ultrastructural immunohistochemical and DNA content analysis of lymphomas having features of interdigitating reticulum cells Cancer. 61: 1594-1601. PMID 3280115  0.152
2011 Dobrowolski SF, Wittwer CT. High-Resolution Melt Profiling Molecular Analysis and Genome Discovery: Second Edition. 81-113. DOI: 10.1002/9781119977438.ch5  0.135
2024 Wittwer CT, Hemmert AC, Kent JO, Rejali NA. DNA melting analysis. Molecular Aspects of Medicine. 97: 101268. PMID 38489863 DOI: 10.1016/j.mam.2024.101268  0.12
1992 Holden JA, Rolfson DH, Wittwer CT. The distribution of immunoreactive topoisomerase II protein in human tissues and neoplasms Oncology Research. 4: 157-166. PMID 1324031  0.108
2011 Wittwer CT. Evolution of polymerase chain reaction: Seminal technology continues to be a work in progress Genetic Engineering and Biotechnology News. 31.  0.102
1990 Rabkin MS, Kjeldsberg CR, Wittwer CT, Marty J. A comparison study of two methods of peanut agglutinin staining with S100 immunostaining in 29 cases of histiocytosis X (Langerhans' cell histiocytosis) Archives of Pathology and Laboratory Medicine. 114: 511-515. PMID 1692202  0.095
1991 O'Connell JB, Renlund DG, Hammond EH, Wittwer CT, Yowell RL, DeWitt CW, Jones KW, Gay WA, Menlove RL, Bristow MR. Sensitization to OKT3 monoclonal antibody in heart transplantation: Correlation with early allograft loss Journal of Heart and Lung Transplantation. 10: 217-222. PMID 1903303  0.089
1989 Wittwer CT, Knape WA, Bristow MR, Gilbert EM, Renlund DG, O’Connell JB, Dewitt CW. The quantitative flow cytometric plasma OKT3 assay: Its potential application in cardiac transplantation Transplantation. 48: 533-535. PMID 2528852  0.082
1987 Gleeson JM, Wittwer CT, Schipke CA, Wilson DE. Effect of carnitine and pantethine on the metabolic abnormalities of acquired total lipodystrophy Current Therapeutic Research - Clinical and Experimental. 41: 83-88.  0.078
1993 Meike A, Wittwer C. Introduced Materials and Colloid Formation: a Report on the Current State of Knowledge Mrs Proceedings. 333. DOI: 10.1557/PROC-333-783  0.067
1988 Wittwer CT, Bristow MR, Michael Gilbert E, Renlund DG, O’Connell JB, Dewitt CW. OKT3 therapy as a cause of high panel-reactive antibodies in serum using standard microcytotoxicity techniques Transplantation. 45: 832-834. PMID 3282368  0.061
1987 Wittwer CT, Smith AM, Ash KO, Dewitt CW. False-positive antibody tests for human immunodeficiency virus in transplant patients with antilymphocyte antibodies Transplantation. 44: 843-844. PMID 3321595  0.047
2000 Paddock S, McDougal D, Heap DM, Herrmann MG, Wittwer CT. Making movies on a weekend Biotechniques. 29: 997. PMID 11084861  0.018
Hide low-probability matches.