Krishna R. Kalari, Ph.D. - Publications

Affiliations: 
2006 University of Iowa, Iowa City, IA 
Area:
Biomedical Engineering, Molecular Biology, Bioinformatics Biology, Pathology

18/151 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Baheti S, Tang X, O'Brien DR, Chia N, Roberts LR, Nelson H, Boughey JC, Wang L, Goetz MP, Kocher JA, Kalari KR. HGT-ID: an efficient and sensitive workflow to detect human-viral insertion sites using next-generation sequencing data. Bmc Bioinformatics. 19: 271. PMID 30016933 DOI: 10.1186/S12859-018-2260-9  0.31
2018 Athreya AP, Gaglio AJ, Cairns J, Kalari KR, Weinshilboum RM, Wang L, Kalbarczyk ZT, Iyer RK. Machine Learning helps Identify New Drug Mechanisms in Triple-Negative Breast Cancer. Ieee Transactions On Nanobioscience. PMID 29994716 DOI: 10.1109/Tnb.2018.2851997  0.356
2018 Wieben ED, Aleff RA, Tang X, Kalari KR, Maguire LJ, Patel SV, Baratz KH, Fautsch MP. Gene expression in the corneal endothelium of Fuchs endothelial corneal dystrophy patients with and without expansion of a trinucleotide repeat in TCF4. Plos One. 13: e0200005. PMID 29966009 DOI: 10.1371/journal.pone.0200005  0.318
2018 Bidadi B, Liu D, Kalari KR, Rubner M, Hein A, Beckmann MW, Rack B, Janni W, Fasching PA, Weinshilboum RM, Wang L. Pathway-Based Analysis of Genome-Wide Association Data Identified SNPs inas Biomarker for Chemotherapy- Induced Neutropenia in Breast Cancer Patients. Frontiers in Pharmacology. 9: 158. PMID 29593529 DOI: 10.3389/Fphar.2018.00158  0.333
2017 Athreya AP, Kalari KR, Cairns J, Gaglio AJ, Wills QF, Niu N, Weinshilboum R, Iyer RK, Wang L. Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer. Oncotarget. 27199-27215. PMID 28423712 DOI: 10.18632/Oncotarget.16109  0.314
2016 Niu N, Liu T, Cairns J, Ly RC, Tan X, Deng M, Fridley BL, Kalari KR, Abo RP, Jenkins G, Batzler A, Carlson EE, Barman P, Moran S, Heyn H, et al. Metformin pharmacogenomics: a genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines. Human Molecular Genetics. 25: 4819-4834. PMID 28173075 DOI: 10.1093/Hmg/Ddw301  0.326
2016 Niu N, Liu T, Cairns J, Ly RC, Tan X, Deng M, Fridley BL, Kalari KR, Abo RP, Jenkins G, Batzler A, Carlson EE, Barman P, Moran S, Heyn H, et al. Metformin Pharmacogenomics: A genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines. Human Molecular Genetics. PMID 27616566 DOI: 10.1093/hmg/ddw301  0.326
2015 Shameer K, Tripathi LP, Kalari KR, Dudley JT, Sowdhamini R. Interpreting functional effects of coding variants: challenges in proteome-scale prediction, annotation and assessment. Briefings in Bioinformatics. PMID 26494363 DOI: 10.1093/bib/bbv084  0.308
2015 Perez EA, Thompson EA, Ballman KV, Anderson SK, Asmann YW, Kalari KR, Eckel-Passow JE, Dueck AC, Tenner KS, Jen J, Fan JB, Geiger XJ, McCullough AE, Chen B, Jenkins RB, et al. Genomic analysis reveals that immune function genes are strongly linked to clinical outcome in the North Central Cancer Treatment Group n9831 Adjuvant Trastuzumab Trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 701-8. PMID 25605861 DOI: 10.1200/Jco.2014.57.6298  0.304
2014 Tong Y, Niu N, Jenkins G, Batzler A, Li L, Kalari KR, Wang L. Identification of genetic variants or genes that are associated with Homoharringtonine (HHT) response through a genome-wide association study in human lymphoblastoid cell lines (LCLs). Frontiers in Genetics. 5: 465. PMID 25628645 DOI: 10.3389/Fgene.2014.00465  0.313
2014 Tang X, Baheti S, Shameer K, Thompson KJ, Wills Q, Niu N, Holcomb IN, Boutet SC, Ramakrishnan R, Kachergus JM, Kocher JP, Weinshilboum RM, Wang L, Thompson EA, Kalari KR. The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data. Nucleic Acids Research. 42: e172. PMID 25352556 DOI: 10.1093/Nar/Gku1005  0.317
2014 Sabarinathan R, Wenzel A, Novotny P, Tang X, Kalari KR, Gorodkin J. Transcriptome-wide analysis of UTRs in non-small cell lung cancer reveals cancer-related genes with SNV-induced changes on RNA secondary structure and miRNA target sites. Plos One. 9: e82699. PMID 24416147 DOI: 10.1371/journal.pone.0082699  0.329
2012 Kalari KR, Rossell D, Necela BM, Asmann YW, Nair A, Baheti S, Kachergus JM, Younkin CS, Baker T, Carr JM, Tang X, Walsh MP, Chai HS, Sun Z, Hart SN, et al. Deep Sequence Analysis of Non-Small Cell Lung Cancer: Integrated Analysis of Gene Expression, Alternative Splicing, and Single Nucleotide Variations in Lung Adenocarcinomas with and without Oncogenic KRAS Mutations. Frontiers in Oncology. 2: 12. PMID 22655260 DOI: 10.3389/Fonc.2012.00012  0.328
2011 Sun Z, Asmann YW, Kalari KR, Bot B, Eckel-Passow JE, Baker TR, Carr JM, Khrebtukova I, Luo S, Zhang L, Schroth GP, Perez EA, Thompson EA. Integrated analysis of gene expression, CpG island methylation, and gene copy number in breast cancer cells by deep sequencing. Plos One. 6: e17490. PMID 21364760 DOI: 10.1371/Journal.Pone.0017490  0.36
2010 Kalari KR, Hebbring SJ, Chai HS, Li L, Kocher JP, Wang L, Weinshilboum RM. Copy number variation and cytidine analogue cytotoxicity: a genome-wide association approach. Bmc Genomics. 11: 357. PMID 20525348 DOI: 10.1186/1471-2164-11-357  0.35
2009 Li L, Fridley BL, Kalari K, Jenkins G, Batzler A, Weinshilboum RM, Wang L. Gemcitabine and arabinosylcytosin pharmacogenomics: genome-wide association and drug response biomarkers. Plos One. 4: e7765. PMID 19898621 DOI: 10.1371/Journal.Pone.0007765  0.318
2008 Kalari KR, Casavant TL, Scheetz TE. A knowledge-based approach to predict intragenic deletions or duplications. Bioinformatics (Oxford, England). 24: 1975-9. PMID 18647756 DOI: 10.1093/Bioinformatics/Btn370  0.434
2006 Kalari KR, Casavant M, Bair TB, Keen HL, Comeron JM, Casavant TL, Scheetz TE. First exons and introns--a survey of GC content and gene structure in the human genome. In Silico Biology. 6: 237-42. PMID 16922687  0.446
Low-probability matches (unlikely to be authored by this person)
2019 Wieben ED, Baratz KH, Aleff RA, Kalari KR, Tang X, Maguire LJ, Patel SV, Fautsch MP. Gene Expression and Missplicing in the Corneal Endothelium of Patients With a TCF4 Trinucleotide Repeat Expansion Without Fuchs' Endothelial Corneal Dystrophy. Investigative Ophthalmology & Visual Science. 60: 3636-3643. PMID 31469403 DOI: 10.1167/iovs.19-27689  0.297
2020 Blatti C, Emad A, Berry MJ, Gatzke L, Epstein M, Lanier D, Rizal P, Ge J, Liao X, Sobh O, Lambert M, Post CS, Xiao J, Groves P, Epstein AT, ... ... Kalari KR, et al. Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform. Plos Biology. 18: e3000583. PMID 31971940 DOI: 10.1371/Journal.Pbio.3000583  0.296
2011 Asmann YW, Hossain A, Necela BM, Middha S, Kalari KR, Sun Z, Chai HS, Williamson DW, Radisky D, Schroth GP, Kocher JP, Perez EA, Thompson EA. A novel bioinformatics pipeline for identification and characterization of fusion transcripts in breast cancer and normal cell lines. Nucleic Acids Research. 39: e100. PMID 21622959 DOI: 10.1093/Nar/Gkr362  0.295
2009 Aksoy P, Zhu MJ, Kalari KR, Moon I, Pelleymounter LL, Eckloff BW, Wieben ED, Yee VC, Weinshilboum RM, Wang L. Cytosolic 5'-nucleotidase III (NT5C3): gene sequence variation and functional genomics. Pharmacogenetics and Genomics. 19: 567-76. PMID 19623099 DOI: 10.1097/Fpc.0B013E32832C14B8  0.295
2011 Moyer AM, Fridley BL, Jenkins GD, Batzler AJ, Pelleymounter LL, Kalari KR, Ji Y, Chai Y, Nordgren KK, Weinshilboum RM. Acetaminophen-NAPQI hepatotoxicity: a cell line model system genome-wide association study. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: 33-41. PMID 21177773 DOI: 10.1093/Toxsci/Kfq375  0.293
2016 Nair AA, Niu N, Tang X, Thompson KJ, Wang L, Kocher JP, Subramanian S, Kalari KR. Circular RNAs and their associations with breast cancer subtypes. Oncotarget. PMID 27829232 DOI: 10.18632/Oncotarget.13134  0.291
2009 Feng Q, Keshtgarpour M, Pelleymounter LL, Moon I, Kalari KR, Eckloff BW, Wieben ED, Weinshilboum RM. Human S-adenosylhomocysteine hydrolase: common gene sequence variation and functional genomic characterization. Journal of Neurochemistry. 110: 1806-17. PMID 19619139 DOI: 10.1111/j.1471-4159.2009.06276.x  0.29
2013 Norton N, Sun Z, Asmann YW, Serie DJ, Necela BM, Bhagwate A, Jen J, Eckloff BW, Kalari KR, Thompson KJ, Carr JM, Kachergus JM, Geiger XJ, Perez EA, Thompson EA. Gene expression, single nucleotide variant and fusion transcript discovery in archival material from breast tumors. Plos One. 8: e81925. PMID 24278466 DOI: 10.1371/Journal.Pone.0081925  0.289
2019 Felts SJ, Tang X, Willett B, Van Keulen VP, Hansen MJ, Kalari KR, Pease LR. Stochastic changes in gene expression promote chaotic dysregulation of homeostasis in clonal breast tumors. Communications Biology. 2: 206. PMID 31925044 DOI: 10.1038/s42003-019-0460-0  0.289
2019 Felts SJ, Tang X, Willett B, Van Keulen VP, Hansen MJ, Kalari KR, Pease LR. Stochastic changes in gene expression promote chaotic dysregulation of homeostasis in clonal breast tumors. Communications Biology. 2: 206. PMID 31240244 DOI: 10.1038/s42003-019-0460-0  0.289
2016 Ingle JN, Xie F, Ellis MJ, Goss PE, Shepherd LE, Chapman JW, Chen BE, Kubo M, Furukawa Y, Momozawa Y, Stearns V, Pritchard KI, Barman P, Carlson EE, Goetz MP, ... ... Kalari KR, et al. Genetic polymorphisms in the long noncoding RNA MIR2052HG offer a pharmacogenomic basis for the response of breast cancer patients to aromatase inhibitor therapy. Cancer Research. PMID 27758888 DOI: 10.1158/0008-5472.Can-16-1371  0.285
2013 Kalari KR, Necela BM, Tang X, Thompson KJ, Lau M, Eckel-Passow JE, Kachergus JM, Anderson SK, Sun Z, Baheti S, Carr JM, Baker TR, Barman P, Radisky DC, Joseph RW, et al. An integrated model of the transcriptome of HER2-positive breast cancer. Plos One. 8: e79298. PMID 24223926 DOI: 10.1371/Journal.Pone.0079298  0.283
2022 Aalam SMM, Tang X, Song J, Ray U, Russell SJ, Weroha SJ, Bakkum-Gamez J, Shridhar V, Sherman ME, Eaves CJ, Knapp DJHF, Kalari KR, Kannan N. DNA barcoded competitive clone-initiating cell analysis reveals novel features of metastatic growth in a cancer xenograft model. Nar Cancer. 4: zcac022. PMID 35875052 DOI: 10.1093/narcan/zcac022  0.279
2014 Perez EA, Thompson EA, Anderson SK, Asmann YW, Kalari KR, Eckel-Passow J, Dueck AC, Tenner KS, Jen J, Fan J, Geiger X, McCullough AE, Chen B, Zschunke M, Jenkins RB, et al. Association of genomic analysis of immune function genes and clinical outcome in the NCCTG (Alliance) N9831 adjuvant trastuzumab trial. Journal of Clinical Oncology. 32: 509-509. DOI: 10.1200/Jco.2014.32.15_Suppl.509  0.278
2008 Li L, Fridley B, Kalari K, Jenkins G, Batzler A, Safgren S, Hildebrandt M, Ames M, Schaid D, Wang L. Gemcitabine and cytosine arabinoside cytotoxicity: association with lymphoblastoid cell expression. Cancer Research. 68: 7050-8. PMID 18757419 DOI: 10.1158/0008-5472.Can-08-0405  0.27
2017 Emad A, Cairns J, Kalari KR, Wang L, Sinha S. Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance. Genome Biology. 18: 153. PMID 28800781 DOI: 10.1186/S13059-017-1282-3  0.269
2022 Sicotte H, Kalari KR, Qin S, Dehm SM, Bhargava V, Gormley M, Tan W, Sinnwell JP, Hillman DW, Li Y, Vedell PT, Carlson RE, Bryce AH, Jimenez RE, Weinshilboum RM, et al. Molecular profile changes in castrate resistant prostate cancer patients pre and post-abiraterone/prednisone treatment. Molecular Cancer Research : McR. PMID 36135372 DOI: 10.1158/1541-7786.MCR-22-0099  0.268
2017 Liu D, Ho MF, Schaid DJ, Scherer SE, Kalari K, Liu M, Biernacka J, Yee V, Evans J, Carlson E, Goetz MP, Kubo M, Wickerham DL, Wang L, Ingle JN, et al. Breast cancer chemoprevention pharmacogenomics: Deep sequencing and functional genomics of the ZNF423 and CTSO genes. Npj Breast Cancer. 3: 30. PMID 28856246 DOI: 10.1038/s41523-017-0036-4  0.267
2010 Li F, Fridley BL, Matimba A, Kalari KR, Pelleymounter L, Moon I, Ji Y, Jenkins GD, Batzler A, Wang L, Weinshilboum RM. Ecto-5'-nucleotidase and thiopurine cellular circulation: association with cytotoxicity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 2329-38. PMID 20855458 DOI: 10.1124/Dmd.110.035220  0.266
2012 Asmann YW, Middha S, Hossain A, Baheti S, Li Y, Chai HS, Sun Z, Duffy PH, Hadad AA, Nair A, Liu X, Zhang Y, Klee EW, Kalari KR, Kocher JP. TREAT: a bioinformatics tool for variant annotations and visualizations in targeted and exome sequencing data. Bioinformatics (Oxford, England). 28: 277-8. PMID 22088845 DOI: 10.1093/Bioinformatics/Btr612  0.266
2010 Niu N, Qin Y, Fridley BL, Hou J, Kalari KR, Zhu M, Wu TY, Jenkins GD, Batzler A, Wang L. Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines. Genome Research. 20: 1482-92. PMID 20923822 DOI: 10.1101/Gr.107672.110  0.26
2017 Thompson KJ, Ingle JN, Tang X, Chia N, Jeraldo PR, Walther-Antonio MR, Kandimalla KK, Johnson S, Yao JZ, Harrington SC, Suman VJ, Wang L, Weinshilboum RL, Boughey JC, Kocher JP, ... ... Kalari KR, et al. A comprehensive analysis of breast cancer microbiota and host gene expression. Plos One. 12: e0188873. PMID 29190829 DOI: 10.1371/Journal.Pone.0188873  0.26
2019 Vu TN, Nguyen HN, Calza S, Kalari KR, Wang L, Pawitan Y. Cell-level somatic mutation detection from single-cell RNA-sequencing. Bioinformatics (Oxford, England). PMID 31028395 DOI: 10.1093/Bioinformatics/Btz288  0.258
2020 Zhang L, Sarangi V, Moon I, Yu J, Liu D, Devarajan S, Reid JM, Kalari KR, Wang L, Weinshilboum R. CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants. Clinical and Translational Science. PMID 32004414 DOI: 10.1111/Cts.12758  0.254
2015 Ellingson MS, Hart SN, Kalari KR, Suman V, Schahl KA, Dockter TJ, Felten SJ, Sinnwell JP, Thompson KJ, Tang X, Vedell PT, Barman P, Sicotte H, Eckel-Passow JE, Northfelt DW, et al. Exome sequencing reveals frequent deleterious germline variants in cancer susceptibility genes in women with invasive breast cancer undergoing neoadjuvant chemotherapy Breast Cancer Research and Treatment. DOI: 10.1007/s10549-015-3545-6  0.254
2019 Cairns J, Ingle JN, Kalari KR, Shepherd LE, Kubo M, Goetz MP, Weinshilboum RM, Wang L. The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1. Breast Cancer Research : Bcr. 21: 47. PMID 30944027 DOI: 10.1186/S13058-019-1130-3  0.253
2019 Dudenkov TM, Liu D, Cairns J, Devarajan S, Zhuang Y, Ingle JN, Buzdar AU, Robson ME, Kubo M, Batzler A, Barman P, Jenkins GD, Carlson EE, Goetz MP, Northfelt DW, ... ... Kalari KR, et al. Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction between SLC38A7 and ALPPL2. Clinical Pharmacology and Therapeutics. PMID 30648747 DOI: 10.1002/Cpt.1359  0.251
2021 Zhang L, Sarangi V, Ho MF, Moon I, Kalari KR, Wang L, Weinshilboum RM. : Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 33658230 DOI: 10.1124/dmd.120.000264  0.251
2014 Li L, Fridley BL, Kalari K, Niu N, Jenkins G, Batzler A, Abo RP, Schaid D, Wang L. Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines Bmc Genomics. 15. PMID 24483146 DOI: 10.1186/1471-2164-15-93  0.248
2014 Kalari KR, Nair AA, Bhavsar JD, O'Brien DR, Davila JI, Bockol MA, Nie J, Tang X, Baheti S, Doughty JB, Middha S, Sicotte H, Thompson AE, Asmann YW, Kocher JP. MAP-RSeq: Mayo Analysis Pipeline for RNA sequencing. Bmc Bioinformatics. 15: 224. PMID 24972667 DOI: 10.1186/1471-2105-15-224  0.248
2018 Tu X, Kahila MM, Zhou Q, Yu J, Kalari KR, Wang L, Harmsen WS, Yuan J, Boughey JC, Goetz MP, Sarkaria JN, Lou Z, Mutter RW. ATR inhibition is a promising radiosensitizing strategy for triple negative breast cancer. Molecular Cancer Therapeutics. PMID 30166399 DOI: 10.1158/1535-7163.MCT-18-0470  0.248
2011 Reams RR, Kalari KR, Wang H, Odedina FT, Soliman KF, Yates C. Detecting gene-gene interactions in prostate disease in African American men. Infectious Agents and Cancer. 6: S1. PMID 21992608 DOI: 10.1186/1750-9378-6-S2-S1  0.247
2018 Ingle JN, Kalari KR, Wickerham DL, von Minckwitz G, Fasching PA, Furukawa Y, Mushiroda T, Goetz MP, Barman P, Carlson EE, Rastogi P, Costantino JP, Cairns J, Paik S, Bear HD, et al. Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab. Pharmacogenetics and Genomics. 28: 147-152. PMID 29768301 DOI: 10.1097/FPC.0000000000000337  0.247
2018 Liu D, Qin S, Ray B, Kalari KR, Wang L, Weinshilboum RM. Single Nucleotide Polymorphisms (SNPs) Distant from Xenobiotic Response Elements Can Modulate Aryl Hydrocarbon Receptor Function: SNP-Dependent Induction. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29980579 DOI: 10.1124/dmd.118.082164  0.244
2009 Niu N, Manickam V, Kalari KR, Moon I, Pelleymounter LL, Eckloff BW, Wieben ED, Schaid DJ, Wang L. Human glucocorticoid receptor alpha gene (NR3C1) pharmacogenomics: gene resequencing and functional genomics. The Journal of Clinical Endocrinology and Metabolism. 94: 3072-84. PMID 19435830 DOI: 10.1210/jc.2008-2109  0.239
2018 West DC, Kocherginsky M, Tonsing-Carter EY, Dolcen DN, Hosfield DJ, Lastra RR, Sinnwell JP, Thompson KJ, Bowie KR, Harkless RV, Skor MN, Pierce CF, Styke SC, Kim CR, de Wet L, ... ... Kalari KR, et al. Discovery of a glucocorticoid receptor (GR) activity signature using selective GR antagonism in ER-negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29636357 DOI: 10.1158/1078-0432.Ccr-17-2793  0.238
2016 Ho MF, Bongartz T, Liu M, Kalari KR, Goss PE, Shepherd LE, Goetz MP, Kubo M, Ingle JN, Wang L, Weinshilboum RM. Estrogen, SNP-Dependent Chemokine Expression and Selective Estrogen Receptor Modulator Regulation. Molecular Endocrinology (Baltimore, Md.). me20151267. PMID 26866883 DOI: 10.1210/me.2015-1267  0.235
2017 Ho MF, Ingle JN, Bongartz T, Kalari KR, Goss PE, Shepherd LE, Mushiroda T, Kubo M, Wang L, Weinshilboum RM. TCL1A SNPs and estrogen-mediated toll-like receptor-MYD88-dependent NF-κB activation: SNP and SERM-dependent modification of inflammation and immune response. Molecular Pharmacology. PMID 28615284 DOI: 10.1124/Mol.117.108340  0.234
2018 Vu TN, Wills QF, Kalari KR, Niu N, Wang L, Pawitan Y, Rantalainen M. Isoform-level gene expression patterns in single-cell RNA-sequencing data. Bioinformatics (Oxford, England). PMID 29490015 DOI: 10.1093/Bioinformatics/Bty100  0.231
2022 Qin S, Gao H, Kim W, Zhang H, Gu Y, Kalari KR, Sinnwell JP, Scholz JA, Xie F, Yin P, Yu J, Qin B, Zhuang Y, Wei L, Tan W, et al. Biomarkers for predicting abiraterone treatment outcome and selecting alternative therapies in castration-resistant prostate cancer. Clinical Pharmacology and Therapeutics. PMID 35288936 DOI: 10.1002/cpt.2582  0.227
2022 Thompson KJ, Leon-Ferre RA, Sinnwell JP, Zahrieh DM, Suman VJ, Metzger FO, Asad S, Stover DG, Carey L, Sikov WM, Ingle JN, Liu MC, Carter JM, Klee EW, Weinshilboum RM, ... ... Kalari KR, et al. Luminal androgen receptor breast cancer subtype and investigation of the microenvironment and neoadjuvant chemotherapy response. Nar Cancer. 4: zcac018. PMID 35734391 DOI: 10.1093/narcan/zcac018  0.227
2020 Cairns J, Ingle JN, Dudenkov TTM, Kalari KR, Carlson EE, Na J, Buzdar AU, Robson ME, Ellis MJ, Goss PE, Shepherd LE, Goodnature B, Goetz MP, Weinshilboum RM, Li H, et al. Pharmacogenomics of aromatase inhibitors in postmenopausal breast cancer and additional mechanisms of anastrozole action. Jci Insight. PMID 32701512 DOI: 10.1172/Jci.Insight.137571  0.226
2016 Vu TN, Wills QF, Kalari KR, Niu N, Wang L, Rantalainen M, Pawitan Y. Beta-Poisson model for single-cell RNA-seq data analyses. Bioinformatics (Oxford, England). PMID 27153638 DOI: 10.1093/Bioinformatics/Btw202  0.225
2015 Ellingson MS, Hart SN, Kalari KR, Suman V, Schahl KA, Dockter TJ, Felten SJ, Sinnwell JP, Thompson KJ, Tang X, Vedell PT, Barman P, Sicotte H, Eckel-Passow JE, Northfelt DW, et al. Exome sequencing reveals frequent deleterious germline variants in cancer susceptibility genes in women with invasive breast cancer undergoing neoadjuvant chemotherapy. Breast Cancer Research and Treatment. 153: 435-43. PMID 26296701 DOI: 10.1007/S10549-015-3545-6  0.223
2019 Ingle JN, Kalari KR, Momozawa Y, Kubo M, Furukawa Y, Shepherd LE, Ellis MJ, Goss PE, Barman P, Carlson EE, Sinnwell JP, Tang X, Goetz MP, Chen BE, Cairns J, et al. Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer. Pharmacogenetics and Genomics. PMID 31211741 DOI: 10.1097/Fpc.0000000000000382  0.223
2023 Blatti C, de la Fuente Cedeño J, Gao H, Marín-Goñi I, Chen Z, Zhao SD, Tan W, Weinshilboum R, Kalari KR, Wang L, Hernaez M. Bayesian machine learning enables identification of transcriptional network disruptions associated with drug-resistant prostate cancer. Cancer Research. PMID 36779846 DOI: 10.1158/0008-5472.CAN-22-1910  0.221
2012 Niu N, Schaid DJ, Abo RP, Kalari K, Fridley BL, Feng Q, Jenkins G, Batzler A, Brisbin AG, Cunningham JM, Li L, Sun Z, Yang P, Wang L. Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study. Bmc Cancer. 12: 422. PMID 23006423 DOI: 10.1186/1471-2407-12-422  0.218
2016 Gupta M, Neavin D, Liu D, Biernacka J, Hall-Flavin D, Bobo WV, Frye MA, Skime M, Jenkins GD, Batzler A, Kalari K, Matson W, Bhasin SS, Zhu H, Mushiroda T, et al. TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics. Molecular Psychiatry. PMID 26903268 DOI: 10.1038/Mp.2016.6  0.216
2014 Dudenkov TM, Ingle JN, Buzdar A, Robson ME, Kubo M, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Fridley BL, Goetz MP, Northfelt DW, Perez EA, Williard CV, Kalari KR, et al. Genes associated with serum estrone, estrone conjugates, and androstenedione concentrations in postmenopausal women with estrogen receptor-positive breast cancer. Journal of Clinical Oncology. 32: 593-593. DOI: 10.1200/Jco.2014.32.15_Suppl.593  0.211
2018 Kalari KR, Sinnwell JP, Thompson KJ, Tang X, Carlson EE, Yu J, Vedell PT, Ingle JN, Weinshilboum RM, Boughey JC, Wang L, Goetz MP, Suman V. PANOPLY: Omics-Guided Drug Prioritization Method Tailored to an Individual Patient. Jco Clinical Cancer Informatics. 1-11. PMID 30652605 DOI: 10.1200/CCI.18.00012  0.21
2012 Asmann YW, Necela BM, Kalari KR, Hossain A, Baker TR, Carr JM, Davis C, Getz JE, Hostetter G, Li X, McLaughlin SA, Radisky DC, Schroth GP, Cunliffe HE, Perez EA, et al. Detection of redundant fusion transcripts as biomarkers or disease-specific therapeutic targets in breast cancer. Cancer Research. 72: 1921-8. PMID 22496456 DOI: 10.1158/0008-5472.Can-11-3142  0.21
2021 He Y, Wang L, Wei T, Xiao YT, Sheng H, Su H, Hollern DP, Zhang X, Ma J, Wen S, Xie H, Yan Y, Pan Y, Hou X, Tang X, ... ... Kalari KR, et al. FOXA1 overexpression suppresses interferon signaling and immune response in cancer. The Journal of Clinical Investigation. PMID 34101624 DOI: 10.1172/JCI147025  0.209
2021 Zhuang Y, Grainger JM, Vedell PT, Yu J, Moyer AM, Gao H, Fan XY, Qin S, Liu D, Kalari KR, Goetz MP, Boughey JC, Weinshilboum RM, Wang L. Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX). Npj Breast Cancer. 7: 79. PMID 34145270 DOI: 10.1038/s41523-021-00285-x  0.209
2020 Nair AA, Tang X, Thompson KJ, Vedell PT, Kalari KR, Subramanian S. Frequency of MicroRNA Response Elements Identifies Pathologically Relevant Signaling Pathways in Triple-Negative Breast Cancer. Iscience. 23: 101249. PMID 32629614 DOI: 10.1016/j.isci.2020.101249  0.209
2014 Thompson EA, Necela BM, Carr JM, Kachergus JM, Serie D, Kalari KR, Asmann YW, Perez EA. Identification and targeting of M-phase progression downstream of HER2 in trastuzumab-sensitive and -resistant breast cancer cell lines. Journal of Clinical Oncology. 32: 612-612. DOI: 10.1200/Jco.2014.32.15_Suppl.612  0.207
2008 Wang L, Kumar S, Fridley BL, Kalari KR, Moon I, Pelleymounter LL, Hildebrandt MA, Batzler A, Eckloff BW, Wieben ED, Greipp PR. Proteasome beta subunit pharmacogenomics: gene resequencing and functional genomics. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3503-13. PMID 18519783 DOI: 10.1158/1078-0432.Ccr-07-5150  0.203
2018 Yu J, Qin B, Moyer AM, Nowsheen S, Liu T, Qin S, Zhuang Y, Liu D, Lu SW, Kalari KR, Visscher DW, Copland JA, McLaughlin SA, Moreno-Aspitia A, Northfelt DW, et al. DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine. The Journal of Clinical Investigation. PMID 29708513 DOI: 10.1172/Jci97924  0.201
2018 Liu D, Ray B, Neavin DR, Zhang J, Athreya AP, Biernacka JM, Bobo WV, Hall-Flavin DK, Skime MK, Zhu H, Jenkins GD, Batzler A, Kalari KR, Boakye-Agyeman F, Matson WR, et al. Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics. Translational Psychiatry. 8: 10. PMID 29317604 DOI: 10.1038/S41398-017-0056-8  0.199
2022 Aspros KGM, Carter JM, Hoskin TL, Suman VJ, Subramaniam M, Emch MJ, Ye Z, Sun Z, Sinnwell JP, Thompson KJ, Tang X, Rodman EPB, Wang X, Nelson AW, Chernukhin I, ... ... Kalari KR, et al. Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB/p65 signaling in triple negative breast cancer. Npj Breast Cancer. 8: 20. PMID 35177654 DOI: 10.1038/s41523-022-00387-0  0.197
2012 Li L, Schaid DJ, Fridley BL, Kalari KR, Jenkins GD, Abo RP, Batzler A, Moon I, Pelleymounter L, Eckloff BW, Wieben ED, Sun Z, Yang P, Wang L. Gemcitabine metabolic pathway genetic polymorphisms and response in patients with non-small cell lung cancer. Pharmacogenetics and Genomics. 22: 105-16. PMID 22173087 DOI: 10.1097/Fpc.0B013E32834Dd7E2  0.193
2021 Myasoedova E, Athreya AP, Crowson CS, Davis JM, Warrington KJ, Walchak RC, Carlson E, Kalari KR, Bongartz T, Tak PP, van Vollenhoven RF, Padyukov L, Emery P, Morgan A, Wang L, et al. Towards Individualized Prediction of Response to Methotrexate in Early Rheumatoid Arthritis: a Pharmacogenomics-driven Machine Learning Approach. Arthritis Care & Research. PMID 34902228 DOI: 10.1002/acr.24834  0.19
2020 Norton N, Youssef B, Hillman DW, Nassar A, Geiger XJ, Necela BM, Liu H, Ruddy KJ, Polley MC, Ingle JN, Couch FJ, Perez EA, Liu MC, Carter JM, Leon-Ferre RA, ... ... Kalari KR, et al. Folate receptor alpha expression associates with improved disease-free survival in triple negative breast cancer patients. Npj Breast Cancer. 6: 4. PMID 33531479 DOI: 10.1038/s41523-020-0147-1  0.188
2020 Norton N, Youssef B, Hillman DW, Nassar A, Geiger XJ, Necela BM, Liu H, Ruddy KJ, Polley MC, Ingle JN, Couch FJ, Perez EA, Liu MC, Carter JM, Leon-Ferre RA, ... ... Kalari KR, et al. Folate receptor alpha expression associates with improved disease-free survival in triple negative breast cancer patients. Npj Breast Cancer. 6: 4. PMID 32047850 DOI: 10.1038/s41523-020-0147-1  0.187
2015 Necela BM, Crozier JA, Andorfer CA, Lewis-Tuffin L, Kachergus JM, Geiger XJ, Kalari KR, Serie DJ, Sun Z, Aspita AM, O'Shannessy DJ, Maltzman JD, McCullough AE, Pockaj BA, Cunliffe HE, et al. Folate receptor-α (FOLR1) expression and function in triple negative tumors. Plos One. 10: e0122209. PMID 25816016 DOI: 10.1371/Journal.Pone.0122209  0.186
2022 Kohale IN, Yu J, Zhuang Y, Fan X, Reddy RJ, Sinnwell J, Kalari KR, Boughey JC, Carter JM, Goetz MP, Wang L, White FM. Identification of Src Family Kinases as Potential Therapeutic Targets for Chemotherapy-Resistant Triple Negative Breast Cancer. Cancers. 14. PMID 36077757 DOI: 10.3390/cancers14174220  0.186
2021 Cairns J, Kalari KR, Ingle JN, Shepherd LE, Ellis MJ, Goss PE, Barman P, Carlson EE, Goodnature B, Goetz MP, Weinshilboum RM, Gao H, Wang L. Interaction between SNP Genotype and Efficacy of Anastrozole and Exemestane in Early Stage Breast Cancer. Clinical Pharmacology and Therapeutics. PMID 34048027 DOI: 10.1002/cpt.2311  0.185
2017 Goetz MP, Kalari KR, Suman VJ, Moyer AM, Yu J, Visscher DW, Dockter TJ, Vedell PT, Sinnwell JP, Tang X, Thompson KJ, McLaughlin SA, Moreno-Aspitia A, Copland JA, Northfelt DW, et al. Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer. Journal of the National Cancer Institute. 109. PMID 28376176 DOI: 10.1093/Jnci/Djw306  0.184
2014 Boughey JC, Yu J, Yin P, Gao B, Sinnwell JP, Moyer AM, Visscher DW, Conners AL, Dockter TJ, Kalari KR, Jones KN, McLaughlin SA, Copland JA, Moreno-Aspitia A, Northfelt DW, et al. Patient-derived xenografts from breast cancer patients before and after neoadjuvant chemotherapy: A prospective study. Journal of Clinical Oncology. 32: 11130-11130. DOI: 10.1200/Jco.2014.32.15_Suppl.11130  0.18
2017 Wang L, Dehm SM, Hillman DW, Sicotte H, Tan W, Gormley M, Bhargava V, Jimenez R, Xie F, Yin P, Qin S, Quevedo F, Costello BA, Pitot HC, Ho T, ... ... Kalari KR, et al. A Prospective Genome-Wide Study of Prostate Cancer Metastases Reveals Association of Wnt Pathway Activation and Increased Cell Cycle Proliferation with Primary Resistance to Abiraterone Acetate-Prednisone. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 29069303 DOI: 10.1093/Annonc/Mdx689  0.177
2020 Chumsri S, Carter JM, Ma Y, Hinerfeld D, Brauer HA, Warren S, Nielsen TO, Asleh K, Joensuu H, Perez EA, Leon-Ferre RA, Hillman DW, Boughey JC, Liu MC, Ingle JN, ... Kalari KR, et al. Role of intratumoral NK cells in triple-negative breast cancer in the FinXX trial and Mayo Clinic cohort. Journal of Clinical Oncology. 38: 510-510. DOI: 10.1200/Jco.2020.38.15_Suppl.510  0.177
2011 Murray NR, Kalari KR, Fields AP. Protein kinase Cι expression and oncogenic signaling mechanisms in cancer. Journal of Cellular Physiology. 226: 879-87. PMID 20945390 DOI: 10.1002/Jcp.22463  0.177
2020 John A, Qin B, Kalari KR, Wang L, Yu J. Patient-specific multi-omics models and the application in personalized combination therapy. Future Oncology (London, England). PMID 32462937 DOI: 10.2217/Fon-2020-0119  0.176
2018 Lowe VJ, Kalari KR, Kandimalla KK. Your brain scan may be a reflection of your genes. Brain : a Journal of Neurology. 141: 2539-2541. PMID 30169591 DOI: 10.1093/Brain/Awy226  0.173
2019 Shee K, Wells JD, Ung M, Hampsch RA, Traphagen NA, Yang W, Liu SC, Zeldenrust MA, Wang L, Kalari KR, Yu J, Boughey JC, Demidenko E, Kettenbach AN, Cheng C, et al. A transcriptionally-definable subgroup of triple-negative breast and ovarian cancer samples shows sensitivity to HSP90 inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31558472 DOI: 10.1158/1078-0432.Ccr-18-2213  0.173
2017 Dudenkov TM, Ingle JN, Buzdar AU, Robson ME, Kubo M, Ibrahim-Zada I, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Barman P, Goetz MP, Northfelt DW, Moreno-Aspita A, Williard CV, ... Kalari KR, et al. SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway. Breast Cancer Research and Treatment. PMID 28429243 DOI: 10.1007/S10549-017-4243-3  0.172
2011 Feng Q, Kalari K, Fridley BL, Jenkins G, Ji Y, Abo R, Hebbring S, Zhang J, Nye MD, Leeder JS, Weinshilboum RM. Betaine-homocysteine methyltransferase: human liver genotype-phenotype correlation. Molecular Genetics and Metabolism. 102: 126-33. PMID 21093336 DOI: 10.1016/J.Ymgme.2010.10.010  0.171
2016 Hart SN, Ellingson MS, Schahl K, Vedell PT, Carlson RE, Sinnwell JP, Barman P, Sicotte H, Eckel-Passow JE, Wang L, Kalari KR, Qin R, Kruisselbrink TM, Jimenez RE, Bryce AH, et al. Determining the frequency of pathogenic germline variants from exome sequencing in patients with castrate-resistant prostate cancer. Bmj Open. 6: e010332. PMID 27084275 DOI: 10.1136/Bmjopen-2015-010332  0.17
2020 Ingle JN, Kalari KR, Barman P, Shepherd LE, Ellis MJ, Goss PE, Buzdar AU, Robson ME, Cairns J, Carlson EE, Eyman Casey A, Hoskin TL, Goodnature BA, Haddad TC, Goetz MP, et al. Single-nucleotide polymorphism biomarkers of adjuvant anastrozole-induced estrogen suppression in early breast cancer. Pharmacogenetics and Genomics. PMID 32649577 DOI: 10.1097/Fpc.0000000000000415  0.169
2023 Tang X, Thompson KJ, Kalari KR, Sinnwell JP, Suman VJ, Vedell PT, McLaughlin SA, Northfelt DW, Aspitia AM, Gray RJ, Carter JM, Weinshilboum R, Wang L, Boughey JC, Goetz MP. Integration of multiomics data shows down regulation of mismatch repair and tubulin pathways in triple-negative chemotherapy-resistant breast tumors. Breast Cancer Research : Bcr. 25: 57. PMID 37226243 DOI: 10.1186/s13058-023-01656-x  0.168
2024 Braune EB, Geist F, Tang X, Kalari K, Boughey J, Wang L, Leon-Ferre RA, D'Assoro AB, Ingle JN, Goetz MP, Kreis J, Wang K, Foukakis T, Seshire A, Wienke D, et al. Identification of a Notch transcriptomic signature for breast cancer. Breast Cancer Research : Bcr. 26: 4. PMID 38172915 DOI: 10.1186/s13058-023-01757-7  0.167
2021 Cairns J, Ingle JN, Kalari KR, Goetz MP, Weinshilboum RM, Gao H, Li H, Ghanat Bari M, Wang L. Anastrozole regulates fatty acid synthase in breast cancer. Molecular Cancer Therapeutics. PMID 34667110 DOI: 10.1158/1535-7163.MCT-21-0509  0.166
2018 Kohli M, Dehm S, Bhargava V, Gormley M, Sinnwell JP, Tan W, Hillman DW, Li Y, Jimenez RE, Weinshilboum RM, Kalari KR, Wang L, Sicotte H. A transcriptome analysis of castration resistant prostate cancer metastases in a prospective cohort study reveals high expression of AKT pathway genes predictive of long term response to abiraterone acetate/prednisone. Journal of Clinical Oncology. 36: 5038-5038. DOI: 10.1200/Jco.2018.36.15_Suppl.5038  0.165
2017 Yu J, Qin B, Moyer AM, Sinnwell JP, Thompson KJ, Copland JA, Marlow LA, Miller JL, Yin P, Gao B, Minter-Dykhouse K, Tang X, McLaughlin SA, Moreno-Aspitia A, Schweitzer A, ... ... Kalari KR, et al. Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study. Breast Cancer Research : Bcr. 19: 130. PMID 29212525 DOI: 10.1186/S13058-017-0920-8  0.162
2015 Du J, Aleff RA, Soragni E, Kalari K, Nie J, Tang X, Davila J, Kocher JP, Patel SV, Gottesfeld JM, Baratz KH, Wieben ED. RNA toxicity and missplicing in the common eye disease fuchs endothelial corneal dystrophy. The Journal of Biological Chemistry. 290: 5979-90. PMID 25593321 DOI: 10.1074/Jbc.M114.621607  0.162
2016 Kalari KR, Thompson KJ, Nair AA, Tang X, Bockol MA, Jhawar N, Swaminathan SK, Lowe VJ, Kandimalla KK. BBBomics-Human Blood Brain Barrier Transcriptomics Hub. Frontiers in Neuroscience. 10: 71. PMID 26973449 DOI: 10.3389/Fnins.2016.00071  0.161
2022 Dhar R, Rana S, Srivastava TP, Nayek A, Sharma JB, Kaur D, Kalari KR, Singh H, Karmakar S. India's Opportunities and Challenges in Establishing a Twin Registry: An Unexplored Human Resource for the World's Second-Most Populous Nation. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 1-9. PMID 35786423 DOI: 10.1017/thg.2022.24  0.161
2016 Park JH, Jang M, Tarhan YE, Katagiri T, Sasa M, Miyoshi Y, Kalari KR, Suman VJ, Weinshilboum R, Wang L, Boughey JC, Goetz MP, Nakamura Y. Clonal expansion of antitumor T cells in breast cancer correlates with response to neoadjuvant chemotherapy. International Journal of Oncology. PMID 27278091 DOI: 10.3892/Ijo.2016.3540  0.16
2015 Goetz MP, Sun JX, Suman VJ, Silva GO, Perou CM, Nakamura Y, Cox NJ, Stephens PJ, Miller VA, Ross JS, Chen D, Safgren SL, Kuffel MJ, Ames MM, Kalari KR, et al. Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies. Journal of the National Cancer Institute. 107. PMID 25490892 DOI: 10.1093/Jnci/Dju401  0.159
2017 Wieben ED, Aleff RA, Tang X, Butz ML, Kalari KR, Highsmith EW, Jen J, Vasmatzis G, Patel SV, Maguire LJ, Baratz KH, Fautsch MP. Trinucleotide Repeat Expansion in the Transcription Factor 4 (TCF4) Gene Leads to Widespread mRNA Splicing Changes in Fuchs' Endothelial Corneal Dystrophy. Investigative Ophthalmology & Visual Science. 58: 343-352. PMID 28118661 DOI: 10.1167/Iovs.16-20900  0.159
2021 Boughey JC, Suman VJ, Yu J, Santo K, Sinnwell JP, Carter JM, Kalari KR, Tang X, McLaughlin SA, Moreno-Aspitia A, Northfelt DW, Gray RJ, Hunt KN, Conners AL, Ingle JN, et al. Patient Derived Xenograft Engraftment and Breast Cancer Outcomes in a Prospective Neoadjuvant Study (BEAUTY). Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34078650 DOI: 10.1158/1078-0432.CCR-21-0641  0.159
2014 Jeraldo P, Kalari K, Chen X, Bhavsar J, Mangalam A, White B, Nelson H, Kocher JP, Chia N. IM-TORNADO: a tool for comparison of 16S reads from paired-end libraries. Plos One. 9: e114804. PMID 25506826 DOI: 10.1371/journal.pone.0114804  0.155
2022 Wang L, Scherer SE, Bielinski SJ, Muzny DM, Jones LA, Black JL, Moyer AM, Giri J, Sharp RR, Matey ET, Wright JA, Oyen LJ, Nicholson WT, Wiepert M, Sullard T, ... ... Kalari KR, et al. Implementation of preemptive DNA sequence-based pharmacogenomics testing across a large academic medical center: The Mayo-Baylor RIGHT 10K Study. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 35331649 DOI: 10.1016/j.gim.2022.01.022  0.155
2018 Leon-Ferre RA, Polley M, Liu H, Cafourek V, Boughey JC, Kalari KR, Negron V, Liu MC, Ingle JN, Couch F, Visscher DW, Goetz MP. Tumor-infiltrating lymphocytes in androgen receptor-positive, triple-negative breast cancer. Journal of Clinical Oncology. 36: 5-5. DOI: 10.1200/JCO.2018.36.5_suppl.5  0.153
2021 Polley MC, Leon-Ferre RA, Leung S, Cheng A, Gao D, Sinnwell J, Liu H, Hillman DW, Eyman-Casey A, Gilbert JA, Negron V, Boughey JC, Liu MC, Ingle JN, Kalari K, et al. A clinical calculator to predict disease outcomes in women with triple-negative breast cancer. Breast Cancer Research and Treatment. PMID 33389409 DOI: 10.1007/s10549-020-06030-5  0.152
2013 Sun Z, Asmann YW, Nair A, Zhang Y, Wang L, Kalari KR, Bhagwate AV, Baker TR, Carr JM, Kocher JP, Perez EA, Thompson EA. Impact of library preparation on downstream analysis and interpretation of RNA-Seq data: comparison between Illumina PolyA and NuGEN Ovation protocol. Plos One. 8: e71745. PMID 23977132 DOI: 10.1371/Journal.Pone.0071745  0.151
2010 Hartman WR, Pelleymounter LL, Moon I, Kalari K, Liu M, Wu TY, Escande C, Nin V, Chini EN, Weinshilboum RM. CD38 expression, function, and gene resequencing in a human lymphoblastoid cell line-based model system. Leukemia & Lymphoma. 51: 1315-25. PMID 20470215 DOI: 10.3109/10428194.2010.483299  0.149
2013 Crozier JA, Necela BM, Thompson EA, Geiger X, Moreno-Aspitia A, McCullough AE, Pockaj BA, Cunliffe H, Sun Z, Kalari KR, Kachergus JM, O'Shannessy DJ, Maltzman JD, Ballman KV, Andorfer CA, et al. Increased expression of folate receptor-α (FRA) in triple-negative breast cancer: A potential therapeutic target. Journal of Clinical Oncology. 31: 1037-1037. DOI: 10.1200/Jco.2013.31.15_Suppl.1037  0.149
2022 Wang Z, Tang X, Swaminathan SK, Kandimalla KK, Kalari KR. Mapping the dynamics of insulin-responsive pathways in the blood-brain barrier endothelium using time-series transcriptomics data. Npj Systems Biology and Applications. 8: 29. PMID 35974022 DOI: 10.1038/s41540-022-00235-8  0.149
2013 Joseph RW, Parasramka M, Eckel-Passow JE, Serie D, Wu K, Jiang L, Kalari K, Thompson RH, Huu Ho T, Castle EP, Cheville J, Kwon ED, Thompson EA, Parker A. Inverse association between programmed death ligand 1 and genes in the VEGF pathway in primary clear cell renal cell carcinoma. Cancer Immunology Research. 1: 378-85. PMID 24778130 DOI: 10.1158/2326-6066.Cir-13-0042  0.148
2022 Huang J, Du M, Soupir A, Wang L, Tan W, Kalari KR, Kilari D, Park J, Huang CC, Kohli M, Wang L. Plasma Copy Number Alteration-Based Prognostic and Predictive Multi-Gene Risk Score in Metastatic Castration-Resistant Prostate Cancer. Cancers. 14. PMID 36230636 DOI: 10.3390/cancers14194714  0.148
2009 Pei H, Li L, Fridley BL, Jenkins GD, Kalari KR, Lingle W, Petersen G, Lou Z, Wang L. FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt. Cancer Cell. 16: 259-66. PMID 19732725 DOI: 10.1016/J.Ccr.2009.07.016  0.145
2020 Mars RAT, Yang Y, Ward T, Houtti M, Priya S, Lekatz HR, Tang X, Sun Z, Kalari KR, Korem T, Bhattarai Y, Zheng T, Bar N, Frost G, Johnson AJ, et al. Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome. Cell. PMID 32916129 DOI: 10.1016/J.Cell.2020.08.007  0.144
2016 Hieken TJ, Chen J, Hoskin TL, Walther-Antonio M, Johnson S, Ramaker S, Xiao J, Radisky DC, Knutson KL, Kalari KR, Yao JZ, Baddour LM, Chia N, Degnim AC. The Microbiome of Aseptically Collected Human Breast Tissue in Benign and Malignant Disease. Scientific Reports. 6: 30751. PMID 27485780 DOI: 10.1038/Srep30751  0.143
2021 Salian VS, Wright JA, Vedell PT, Nair S, Li C, Kandimalla M, Tang X, Carmona Porquera EM, Kalari KR, Kandimalla KK. COVID-19 Transmission, Current Treatment, and Future Therapeutic Strategies. Molecular Pharmaceutics. PMID 33464914 DOI: 10.1021/acs.molpharmaceut.0c00608  0.141
2023 Carter JM, Chumsri S, Hinerfeld DA, Ma Y, Wang X, Zahrieh D, Hillman DW, Tenner KS, Kachergus JM, Brauer HA, Warren SE, Henderson D, Shi J, Liu Y, Joensuu H, ... ... Kalari KR, et al. Distinct spatial immune microlandscapes are independently associated with outcomes in triple-negative breast cancer. Nature Communications. 14: 2215. PMID 37072398 DOI: 10.1038/s41467-023-37806-0  0.136
2019 Hunt KN, Conners AL, Goetz MP, O'Connor MK, Suman V, Kalari K, Weinshilboum R, Wang L, Carter J, McLaughlin S, Aspitia AM, Gray R, Northfelt D, Boughey JC. Comparison of Tc-Sestamibi Molecular Breast Imaging and Breast MRI in Patients With Invasive Breast Cancer Receiving Neoadjuvant Chemotherapy. Ajr. American Journal of Roentgenology. 1-12. PMID 31166752 DOI: 10.2214/AJR.18.20628  0.133
2020 Cairns J, Ly RC, Niu N, Kalari KR, Carlson EE, Wang L. CDC25B partners with PP2A to induce AMPK activation and tumor suppression in triple negative breast cancer. Nar Cancer. 2: zcaa039. PMID 33385163 DOI: 10.1093/narcan/zcaa039  0.131
2020 Ingle JN, Cairns J, Suman VJ, Shepherd LE, Fasching PA, Hoskin TL, Singh RJ, Desta Z, Kalari KR, Ellis MJ, Goss PE, Chen BE, Volz B, Barman P, Carlson EE, et al. Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor α. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32098767 DOI: 10.1158/1078-0432.Ccr-19-3091  0.13
2016 Zhang H, Liu H, Chen Y, Yang X, Wang P, Liu T, Deng M, Qin B, Correia C, Lee S, Kim J, Sparks M, Nair AA, Evans DL, Kalari KR, et al. A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choice. Nature Communications. 7: 10201. PMID 26727879 DOI: 10.1038/Ncomms10201  0.129
2020 Jayaraman S, Hou X, Kuffel MJ, Suman VJ, Hoskin TL, Reinicke KE, Monroe DG, Kalari KR, Tang X, Zeldenrust MA, Cheng J, Bruinsma ES, Buhrow SA, McGovern RM, Safgren SL, et al. Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer. Breast Cancer Research : Bcr. 22: 51. PMID 32430040 DOI: 10.1186/S13058-020-01286-7  0.129
2017 Leon-Ferre RA, Polley MY, Liu H, Gilbert JA, Cafourek V, Hillman DW, Elkhanany A, Akinhanmi M, Lilyquist J, Thomas A, Negron V, Boughey JC, Liu MC, Ingle JN, Kalari KR, et al. Impact of histopathology, tumor-infiltrating lymphocytes, and adjuvant chemotherapy on prognosis of triple-negative breast cancer. Breast Cancer Research and Treatment. PMID 28913760 DOI: 10.1007/s10549-017-4499-7  0.125
2019 Giridhar K, Sosa C, Sicotte H, Wang L, Wang L, Sinnwell JP, Tan W, Costello BA, Quevedo F, Pitot HC, Bryce AH, Jimenez RE, Weinshilboum RM, Dehm S, Kalari KR, et al. Evolution of androgen receptor variant (ARV) profiles in serial metastatic solid and liquid biopsies in metastatic castrate resistant prostate cancer (mCRPC) treated with abiraterone acetate/ prednisone (AA/P). Journal of Clinical Oncology. 37: e16559-e16559. DOI: 10.1200/Jco.2019.37.15_Suppl.E16559  0.122
2020 Moyer AM, Dukek B, Duellman P, Schneider B, Wakefield L, Skierka JM, Avula R, Bhagwate AV, Kalari KR, Kreuter JD, Goetz MP, Boughey JC, Black JL, Gandhi MJ. Concordance between predicted HLA type using next generation sequencing data generated for non-HLA purposes and clinical HLA type. Human Immunology. PMID 32546429 DOI: 10.1016/j.humimm.2020.06.002  0.117
2021 Mihindukulasuriya KA, Mars RAT, Johnson AJ, Ward T, Priya S, Lekatz HR, Kalari KR, Droit L, Zheng T, Blekhman R, D'Amato M, Farrugia G, Knights D, Handley SA, Kashyap PC. Multi-omics analyses show disease, diet, and transcriptome interactions with the virome. Gastroenterology. PMID 34245762 DOI: 10.1053/j.gastro.2021.06.077  0.116
2023 Jayaraman S, Wu X, Kalari KR, Tang X, Kuffel MJ, Bruinsma ES, Jalali S, Peterson KL, Correia C, Kudgus RA, Kaufmann SH, Renuse S, Ingle JN, Reid JM, Ames MM, et al. Endoxifen downregulates AKT phosphorylation through protein kinase C beta 1 inhibition in ERα+ breast cancer. Npj Breast Cancer. 9: 101. PMID 38114522 DOI: 10.1038/s41523-023-00606-2  0.116
2021 Yu J, Qin B, Moyer AM, Sinnwell JP, Thompson KJ, Copland JA, Marlow LA, Miller JL, Yin P, Gao B, Minter-Dykhouse K, Tang X, McLaughlin SA, Moreno-Aspitia A, Schweitzer A, ... ... Kalari KR, et al. Correction to: Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study. Breast Cancer Research : Bcr. 23: 41. PMID 33766079 DOI: 10.1186/s13058-021-01420-z  0.116
2017 Leon-Ferre RA, Polley M, Liu H, Gilbert JA, Cafourek V, Hillman DW, Elkhanany A, Akinhanmi M, Negron V, Boughey JC, Liu MC, Ingle JN, Kalari KR, Couch F, Visscher DW, et al. Prognostic value of histopathology, stromal tumor infiltrating lymphocytes (sTILs) and adjuvant chemotherapy (AdjCT) in early stage triple negative breast cancer (TNBC). Journal of Clinical Oncology. 35: 533-533. DOI: 10.1200/JCO.2017.35.15_suppl.533  0.105
2016 Chen J, Chia N, Kalari KR, Yao JZ, Novotna M, Soldan MM, Luckey DH, Marietta EV, Jeraldo PR, Chen X, Weinshenker BG, Rodriguez M, Kantarci OH, Nelson H, Murray JA, et al. Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls. Scientific Reports. 6: 28484. PMID 27346372 DOI: 10.1038/Srep28484  0.1
2020 Leon-Ferre RA, McGrath K, Suman VJ, Carter JM, Kalari KR, Weinshilboum RM, Wang L, Ingle JN, Knutson KL, Ansell SM, Boughey JC, Villasboas JC, Goetz MP. Liquid biopsy of the immune environment: Evaluation of peripheral blood mononuclear cells (PBMCs) with CyTOF and response to trastuzumab (T)-based neoadjuvant chemotherapy (NAC) in HER2+ breast cancer (BC). Journal of Clinical Oncology. 38: 592-592. DOI: 10.1200/Jco.2020.38.15_Suppl.592  0.099
2024 Nelson D, Thompson KJ, Wang L, Wang Z, Eberts P, Azarin SM, Kalari KR, Kandimalla KK. Pericyte Control of Gene Expression in the Blood-Brain Barrier Endothelium: Implications for Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 38393902 DOI: 10.3233/JAD-230907  0.091
2011 Rudin D, Li L, Niu N, Kalari KR, Gilbert JA, Ames MM, Wang L. Gemcitabine Cytotoxicity: Interaction of Efflux and Deamination. Journal of Drug Metabolism & Toxicology. 2: 1-10. PMID 21804948 DOI: 10.4172/2157-7609.1000107  0.089
2015 Ingle JN, Kalari KR, Buzdar AU, Robson ME, Goetz MP, Desta Z, Barman P, Dudenkov TT, Northfelt DW, Perez EA, Flockhart DA, Williard CV, Wang L, Weinshilboum RM. Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole. Steroids. 99: 32-8. PMID 25163006 DOI: 10.1016/j.steroids.2014.08.007  0.088
2020 Mars RAT, Yang Y, Ward T, Houtti M, Priya S, Lekatz HR, Tang X, Sun Z, Kalari KR, Korem T, Bhattarai Y, Zheng T, Bar N, Frost G, Johnson AJ, et al. Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome. Cell. 183: 1137-1140. PMID 33186523 DOI: 10.1016/j.cell.2020.10.040  0.086
2015 Necela BM, Crazier JA, Andorfer CA, Lewis-Tuffin L, Kachergus JM, Geiger XJ, Kalari KR, Serie DJ, Sun Z, Aspita AM, O'Shannessy DJ, Maltzman JD, McCullough AE, Pockaj BA, Cunliffe HE, et al. Folate receptor-a (FOLR1) expression and function in triple negative tumors Plos One. 10. DOI: 10.1371/joumal.pone.0122209  0.083
2023 Emch MJ, Wicik Z, Aspros KGM, Vukajlovic T, Pitel KS, Narum AK, Weivoda MM, Tang X, Kalari KR, Turner RT, Iwaniec UT, Monroe DG, Subramaniam M, Hawse JR. Estrogen-regulated miRs in bone enhance osteoblast differentiation and matrix mineralization. Molecular Therapy. Nucleic Acids. 33: 28-41. PMID 37359348 DOI: 10.1016/j.omtn.2023.05.026  0.08
2021 Carter JM, Polley MC, Leon-Ferre RA, Sinnwell J, Thompson KJ, Wang X, Ma Y, Zahrieh D, Kachergus JM, Solanki M, Boughey JC, Liu MC, Ingle JN, Kalari KR, Couch FJ, et al. Characteristics and spatially-defined immune (micro)landscapes of early-stage PD-L1-positive triple-negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34108182 DOI: 10.1158/1078-0432.CCR-21-0343  0.072
2023 Lewis AR, Costello BA, Quevedo F, Pagliaro LC, Sanhueza C, Weinshilboum RM, Kalari KR, Wang L, Kohli M, Tan W, Giridhar KV. Dynamic assessment of serum chromogranin A and treatment response with abiraterone acetate in metastatic castration-resistant prostate cancer. The Prostate. PMID 36924119 DOI: 10.1002/pros.24498  0.072
2015 Necela BM, Crozier JA, Andorfer CA, Lewis-Tuffin L, Kachergus JM, Geiger XJ, Kalari KR, Serie DJ, Sun Z, Moreno-Aspitia A, O'Shannessy DJ, Maltzman JD, McCullough AE, Pockaj BA, Cunliffe HE, et al. Correction: Folate receptor-α (FOLR1) expression and function in triple negative tumors. Plos One. 10: e0127133. PMID 25928305 DOI: 10.1371/Journal.Pone.0127133  0.062
2017 Niravath P, Chen B, Chapman JW, Agarwal SK, Welschhans RL, Bongartz T, Kalari KR, Shepherd LE, Bartlett J, Pritchard K, Gelmon K, Hilsenbeck SG, Rimawi MF, Osborne CK, Goss PE, et al. Vitamin D Levels, Vitamin D Receptor Polymorphisms, and Inflammatory Cytokines in Aromatase Inhibitor-Induced Arthralgias: An Analysis of CCTG MA.27. Clinical Breast Cancer. PMID 29128193 DOI: 10.1016/J.Clbc.2017.10.009  0.06
2012 Raghu R, Liu CT, Tsai MH, Tang X, Kalari KR, Subramanian S, Sheen LY. Transcriptome analysis of garlic-induced hepatoprotection against alcoholic fatty liver. Journal of Agricultural and Food Chemistry. 60: 11104-19. PMID 23066854 DOI: 10.1021/jf303800p  0.06
2016 Niravath PA, Chen BE, Chapman JA, Agarwal SK, Welschhans RL, Bongartz T, Kalari KR, Shepherd LE, Bartlett J, Pritchard KI, Gelmon KA, Hilsenbeck SG, Rimawi MF, Osborne CK, Goss PE, et al. Vitamin D and aromatase inhibitor-induced arthralgia: Analysis of Canadian cancer trial group MA.27 data. Journal of Clinical Oncology. 34: 10020-10020. DOI: 10.1200/Jco.2016.34.15_Suppl.10020  0.059
2018 Omtri RS, Thompson K, Tang X, Gali CC, Panzenboeck U, Davidson MW, Kalari KR, Kadimalla KK. Differential Effects of Alzheimer's Disease Aβ40 and 42 on Endocytosis and Intraneuronal Trafficking. Neuroscience. PMID 29337241 DOI: 10.1016/J.Neuroscience.2018.01.003  0.05
2021 Zhou AL, Sharda N, Sarma VV, Ahlschwede KM, Curran GL, Tang X, Poduslo JF, Kalari KR, Lowe VJ, Kandimalla KK. Age-Dependent Changes in the Plasma and Brain Pharmacokinetics of Amyloid-β Peptides and Insulin. Journal of Alzheimer's Disease : Jad. PMID 34924382 DOI: 10.3233/JAD-215128  0.032
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