Thomas H. Barker - Publications

Affiliations: 
Biomedical Engineering Georgia Institute of Technology, Atlanta, GA 
Area:
Biomedical Engineering, Nanotechnology, Molecular Biology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Fiore VF, Wong SS, Tran C, Tan C, Xu W, Sulchek T, White ES, Hagood JS, Barker TH. αvβ3 Integrin drives fibroblast contraction and strain stiffening of soft provisional matrix during progressive fibrosis. Jci Insight. 3. PMID 30333317 DOI: 10.1172/jci.insight.97597  0.56
2018 Hay JJ, Rodrigo-Navarro A, Petaroudi M, Bryksin AV, García AJ, Barker TH, Dalby MJ, Salmeron-Sanchez M. Bacteria-Based Materials for Stem Cell Engineering. Advanced Materials (Deerfield Beach, Fla.). e1804310. PMID 30209838 DOI: 10.1002/adma.201804310  0.32
2018 Hardy ET, Wang YJ, Iyer S, Mannino RG, Sakurai Y, Barker TH, Chi T, Youn Y, Wang H, Brown AC, Lam WA. Interdigitated microelectronic bandage augments hemostasis and clot formation at low applied voltage in vitro and in vivo. Lab On a Chip. PMID 30109316 DOI: 10.1039/c8lc00573g  0.8
2018 Welsch N, Brown AC, Barker TH, Lyon LA. Enhancing clot properties through fibrin-specific self-cross-linked PEG side-chain microgels. Colloids and Surfaces. B, Biointerfaces. 166: 89-97. PMID 29549720 DOI: 10.1016/j.colsurfb.2018.03.003  0.8
2017 Cao L, Nicosia J, Larouche J, Zhang Y, Bachman H, Brown AC, Holmgren L, Barker TH. Detection of an Integrin-Binding Mechanoswitch within Fibronectin during Tissue Formation and Fibrosis. Acs Nano. PMID 28699736 DOI: 10.1021/acsnano.7b02755  0.8
2017 Hyatt JS, Douglas AM, Stanley C, Do C, Barker TH, Fernández-Nieves A. Charge segregation in weakly ionized microgels. Physical Review. E. 95: 012608. PMID 28208440 DOI: 10.1103/PhysRevE.95.012608  0.32
2017 Douglas AM, Fragkopoulos AA, Gaines MK, Lyon LA, Fernandez-Nieves A, Barker TH. Dynamic assembly of ultrasoft colloidal networks enables cell invasion within restrictive fibrillar polymers. Proceedings of the National Academy of Sciences of the United States of America. PMID 28100492 DOI: 10.1073/pnas.1607350114  0.48
2016 Robinson ST, Douglas AM, Chadid T, Kuo K, Rajabalan A, Li H, Copland IB, Barker TH, Galipeau J, Brewster LP. A Novel Platelet Lysate Hydrogel for Endothelial Cell and Mesenchymal Stem Cell-Directed Neovascularization. Acta Biomaterialia. PMID 26961805 DOI: 10.1016/j.actbio.2016.03.002  0.32
2016 Brown AC, Hannan RH, Timmins LH, Fernandez JD, Barker TH, Guzzetta NA. Fibrin Network Changes in Neonates after Cardiopulmonary Bypass. Anesthesiology. PMID 26914227 DOI: 10.1097/ALN.0000000000001058  0.32
2015 Fiore VF, Strane PW, Bryksin AV, White ES, Hagood JS, Barker TH. Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction. The Journal of Cell Biology. 211: 173-90. PMID 26459603 DOI: 10.1083/jcb.201505007  0.56
2015 Karumbaiah L, Enam SF, Brown AC, Saxena T, Betancur MI, Barker TH, Bellamkonda RV. Chondroitin Sulfate Glycosaminoglycan Hydrogels Create Endogenous Niches for Neural Stem Cells. Bioconjugate Chemistry. PMID 26440046 DOI: 10.1021/acs.bioconjchem.5b00397  0.8
2015 Brown AC, Dysart MM, Clarke KC, Stabenfeldt SE, Barker TH. Integrin α3β1 binding to fibronectin is dependent on the 9th type III repeat. The Journal of Biological Chemistry. PMID 26318455 DOI: 10.1074/jbc.M115.656702  0.8
2015 Brown AC, Baker SR, Douglas AM, Keating M, Alvarez-Elizondo MB, Botvinick EL, Guthold M, Barker TH. Molecular interference of fibrin's divalent polymerization mechanism enables modulation of multiscale material properties. Biomaterials. 49: 27-36. PMID 25725552 DOI: 10.1016/j.biomaterials.2015.01.010  0.8
2015 Stefanelli VL, Barker TH. The evolution of fibrin-specific targeting strategies Journal of Materials Chemistry B. 3: 1177-1186. DOI: 10.1039/c4tb01769b  0.8
2014 Barker TH, Dysart MM, Brown AC, Douglas AM, Fiore VF, Russell AG. Synergistic effects of particulate matter and substrate stiffness on epithelial-to-mesenchymal transition. Research Report (Health Effects Institute). 3-41. PMID 25669020  0.32
2014 Bryksin AV, Bachman HN, Cooper SW, Balavijayan T, Blackstone RM, Du H, Jenkins JP, Haynes CL, Siemer JL, Fiore VF, Barker TH. One primer to rule them all: universal primer that adds BBa_B0034 ribosomal binding site to any coding standard 10 BioBrick. Acs Synthetic Biology. 3: 956-9. PMID 25524097 DOI: 10.1021/sb500047r  0.8
2014 Qiu Y, Brown AC, Myers DR, Sakurai Y, Mannino RG, Tran R, Ahn B, Hardy ET, Kee MF, Kumar S, Bao G, Barker TH, Lam WA. Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 14430-5. PMID 25246564 DOI: 10.1073/pnas.1322917111  0.8
2014 Dysart MM, Galvis BR, Russell AG, Barker TH. Environmental particulate (PM2.5) augments stiffness-induced alveolar epithelial cell mechanoactivation of transforming growth factor beta. Plos One. 9: e106821. PMID 25226160 DOI: 10.1371/journal.pone.0106821  0.8
2014 Fiore VF, Ju L, Chen Y, Zhu C, Barker TH. Dynamic catch of a Thy-1-α5β1+syndecan-4 trimolecular complex. Nature Communications. 5: 4886. PMID 25216363 DOI: 10.1038/ncomms5886  0.8
2014 Brown AC, Stabenfeldt SE, Ahn B, Hannan RT, Dhada KS, Herman ES, Stefanelli V, Guzzetta N, Alexeev A, Lam WA, Lyon LA, Barker TH. Ultrasoft microgels displaying emergent platelet-like behaviours. Nature Materials. 13: 1108-14. PMID 25194701 DOI: 10.1038/nmat4066  0.8
2014 Boopathy AV, Che PL, Somasuntharam I, Fiore VF, Cabigas EB, Ban K, Brown ME, Narui Y, Barker TH, Yoon YS, Salaita K, García AJ, Davis ME. The modulation of cardiac progenitor cell function by hydrogel-dependent Notch1 activation. Biomaterials. 35: 8103-12. PMID 24974008 DOI: 10.1016/j.biomaterials.2014.05.082  0.8
2014 Barker TH, Heilshorn SC. Biological biomaterials structure, function, property design across the molecular-nano-micro-macro scales. Acta Biomaterialia. 10: 1487. PMID 24530557 DOI: 10.1016/j.actbio.2014.02.001  0.8
2014 Bryksin AV, Brown AC, Baksh MM, Finn MG, Barker TH. Learning from nature - Novel synthetic biology approaches for biomaterial design Acta Biomaterialia. 10: 1761-1769. PMID 24463066 DOI: 10.1016/j.actbio.2014.01.019  0.8
2014 Alonas E, Lifland AW, Gudheti M, Vanover D, Jung J, Zurla C, Kirschman J, Fiore VF, Douglas A, Barker TH, Yi H, Wright ER, Crowe JE, Santangelo PJ. Combining single RNA sensitive probes with subdiffraction-limited and live-cell imaging enables the characterization of virus dynamics in cells. Acs Nano. 8: 302-15. PMID 24351207 DOI: 10.1021/nn405998v  0.8
2014 Brown AC, Barker TH. Fibrin-based biomaterials: modulation of macroscopic properties through rational design at the molecular level. Acta Biomaterialia. 10: 1502-14. PMID 24056097 DOI: 10.1016/j.actbio.2013.09.008  0.8
2013 Clause KC, Barker TH. Extracellular matrix signaling in morphogenesis and repair. Current Opinion in Biotechnology. 24: 830-3. PMID 23726156 DOI: 10.1016/j.copbio.2013.04.011  0.8
2013 Soon AS, Smith MH, Herman ES, Lyon LA, Barker TH. Development of self-assembling mixed protein micelles with temperature-modulated avidities. Advanced Healthcare Materials. 2: 1045-55. PMID 23441099 DOI: 10.1002/adhm.201200330  0.8
2013 Brown AC, Fiore VF, Sulchek TA, Barker TH. Physical and chemical microenvironmental cues orthogonally control the degree and duration of fibrosis-associated epithelial-to-mesenchymal transitions. The Journal of Pathology. 229: 25-35. PMID 23018598 DOI: 10.1002/path.4114  0.8
2013 Clarke KC, Douglas AM, Brown AC, Barker TH, Lyon LA. Colloid-matrix assemblies in regenerative medicine Current Opinion in Colloid and Interface Science. 18: 393-405. DOI: 10.1016/j.cocis.2013.07.004  0.8
2012 Booth AJ, Hadley R, Cornett AM, Dreffs AA, Matthes SA, Tsui JL, Weiss K, Horowitz JC, Fiore VF, Barker TH, Moore BB, Martinez FJ, Niklason LE, White ES. Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation. American Journal of Respiratory and Critical Care Medicine. 186: 866-76. PMID 22936357 DOI: 10.1164/rccm.201204-0754OC  0.8
2012 Markowski MC, Brown AC, Barker TH. Directing epithelial to mesenchymal transition through engineered microenvironments displaying orthogonal adhesive and mechanical cues. Journal of Biomedical Materials Research. Part A. 100: 2119-27. PMID 22615133 DOI: 10.1002/jbm.a.34068  0.8
2012 Cao L, Zeller MK, Fiore VF, Strane P, Bermudez H, Barker TH. Phage-based molecular probes that discriminate force-induced structural states of fibronectin in vivo. Proceedings of the National Academy of Sciences of the United States of America. 109: 7251-6. PMID 22529344 DOI: 10.1073/pnas.1118088109  0.8
2012 Huang X, Yang N, Fiore VF, Barker TH, Sun Y, Morris SW, Ding Q, Thannickal VJ, Zhou Y. Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction. American Journal of Respiratory Cell and Molecular Biology. 47: 340-8. PMID 22461426 DOI: 10.1165/rcmb.2012-0050OC  0.8
2012 Phelps EA, Enemchukwu NO, Fiore VF, Sy JC, Murthy N, Sulchek TA, Barker TH, García AJ. Maleimide cross-linked bioactive PEG hydrogel exhibits improved reaction kinetics and cross-linking for cell encapsulation and in situ delivery. Advanced Materials (Deerfield Beach, Fla.). 24: 64-70, 2. PMID 22174081 DOI: 10.1002/adma.201103574  0.8
2012 Stabenfeldt SE, Gourley M, Krishnan L, Hoying JB, Barker TH. Engineering fibrin polymers through engagement of alternative polymerization mechanisms. Biomaterials. 33: 535-44. PMID 22018389 DOI: 10.1016/j.biomaterials.2011.09.079  0.8
2012 Clause KC, Segura T, Barker TH. Stiffness as an effector of lung branching morphogenesis Asme 2012 Summer Bioengineering Conference, Sbc 2012. 431-432. DOI: 10.1115/SBC2012-80304  0.8
2011 Stabenfeldt SE, Aboujamous NM, Soon AS, Barker TH. A new direction for anticoagulants: inhibiting fibrin assembly with PEGylated fibrin knob mimics. Biotechnology and Bioengineering. 108: 2424-33. PMID 21520023 DOI: 10.1002/bit.23184  0.8
2011 Barker TH. The role of ECM proteins and protein fragments in guiding cell behavior in regenerative medicine. Biomaterials. 32: 4211-4. PMID 21515169 DOI: 10.1016/j.biomaterials.2011.02.027  0.8
2011 Soon AS, Lee CS, Barker TH. Modulation of fibrin matrix properties via knob:hole affinity interactions using peptide-PEG conjugates. Biomaterials. 32: 4406-14. PMID 21435714 DOI: 10.1016/j.biomaterials.2011.02.050  0.8
2011 Mukhatyar VJ, Salmerón-Sánchez M, Rudra S, Mukhopadaya S, Barker TH, García AJ, Bellamkonda RV. Role of fibronectin in topographical guidance of neurite extension on electrospun fibers. Biomaterials. 32: 3958-68. PMID 21377726 DOI: 10.1016/j.biomaterials.2011.02.015  0.8
2011 Brown AC, Rowe JA, Barker TH. Guiding epithelial cell phenotypes with engineered integrin-specific recombinant fibronectin fragments. Tissue Engineering. Part A. 17: 139-50. PMID 20695776 DOI: 10.1089/ten.TEA.2010.0199  0.8
2010 Stabenfeldt SE, Gossett JJ, Barker TH. Building better fibrin knob mimics: an investigation of synthetic fibrin knob peptide structures in solution and their dynamic binding with fibrinogen/fibrin holes. Blood. 116: 1352-9. PMID 20484082 DOI: 10.1182/blood-2009-11-251801  0.8
2010 Park ES, Brown AC, DiFeo MA, Barker TH, Lu H. Continuously perfused, non-cross-contaminating microfluidic chamber array for studying cellular responses to orthogonal combinations of matrix and soluble signals. Lab On a Chip. 10: 571-80. PMID 20162232 DOI: 10.1039/b919294h  0.8
2010 Soon AS, Stabenfeldt SE, Brown WE, Barker TH. Engineering fibrin matrices: the engagement of polymerization pockets through fibrin knob technology for the delivery and retention of therapeutic proteins. Biomaterials. 31: 1944-54. PMID 19914710 DOI: 10.1016/j.biomaterials.2009.10.060  0.8
2010 Fiore VF, Lofton MC, Roser-Page S, Yang SC, Roman J, Murthy N, Barker TH. Polyketal microparticles for therapeutic delivery to the lung. Biomaterials. 31: 810-7. PMID 19846216 DOI: 10.1016/j.biomaterials.2009.09.100  0.8
2009 Carson AE, Barker TH. Emerging concepts in engineering extracellular matrix variants for directing cell phenotype. Regenerative Medicine. 4: 593-600. PMID 19580407 DOI: 10.2217/rme.09.30  0.8
2009 Martino MM, Mochizuki M, Rothenfluh DA, Rempel SA, Hubbell JA, Barker TH. Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability. Biomaterials. 30: 1089-97. PMID 19027948 DOI: 10.1016/j.biomaterials.2008.10.047  0.8
2009 Barker TH, Hagood JS. Getting a grip on Thy-1 signaling. Biochimica Et Biophysica Acta. 1793: 921-3. PMID 19007822 DOI: 10.1016/j.bbamcr.2008.10.004  0.8
2008 Sullivan MM, Puolakkainen PA, Barker TH, Funk SE, Sage EH. Altered tissue repair in hevin-null mice: inhibition of fibroblast migration by a matricellular SPARC homolog. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 16: 310-9. PMID 18318815 DOI: 10.1111/j.1524-475X.2008.00370.x  0.8
2006 Sullivan MM, Barker TH, Funk SE, Karchin A, Seo NS, Höök M, Sanders J, Starcher B, Wight TN, Puolakkainen P, Sage EH. Matricellular hevin regulates decorin production and collagen assembly. The Journal of Biological Chemistry. 281: 27621-32. PMID 16844696 DOI: 10.1074/jbc.M510507200  0.8
2006 Wang H, Workman G, Chen S, Barker TH, Ratner BD, Sage EH, Jiang S. Secreted protein acidic and rich in cysteine (SPARC/osteonectin/BM-40) binds to fibrinogen fragments D and E, but not to native fibrinogen. Matrix Biology : Journal of the International Society For Matrix Biology. 25: 20-6. PMID 16263253 DOI: 10.1016/j.matbio.2005.09.004  0.8
2005 Barker TH, Baneyx G, Cardó-Vila M, Workman GA, Weaver M, Menon PM, Dedhar S, Rempel SA, Arap W, Pasqualini R, Vogel V, Sage EH. SPARC regulates extracellular matrix organization through its modulation of integrin-linked kinase activity. The Journal of Biological Chemistry. 280: 36483-93. PMID 16115889 DOI: 10.1074/jbc.M504663200  0.8
2005 Hagood JS, Prabhakaran P, Kumbla P, Salazar L, MacEwen MW, Barker TH, Ortiz LA, Schoeb T, Siegal GP, Alexander CB, Pardo A, Selman M. Loss of fibroblast Thy-1 expression correlates with lung fibrogenesis. The American Journal of Pathology. 167: 365-79. PMID 16049324 DOI: 10.1016/S0002-9440(10)62982-3  0.8
2005 Barker TH, Framson P, Puolakkainen PA, Reed M, Funk SE, Sage EH. Matricellular homologs in the foreign body response: hevin suppresses inflammation, but hevin and SPARC together diminish angiogenesis. The American Journal of Pathology. 166: 923-33. PMID 15743803 DOI: 10.1016/S0002-9440(10)62312-7  0.8
2005 Yang LR, Barker TH, Baldi L, Wurm FM, Lord ST, Frey P, Hubbell JA. Recombinant chimeric fibrinogen synthesis for direct incorporation of protein therapeutics European Cells and Materials. 10: STE15.  0.8
2004 Barker TH, Grenett HE, MacEwen MW, Tilden SG, Fuller GM, Settleman J, Woods A, Murphy-Ullrich J, Hagood JS. Thy-1 regulates fibroblast focal adhesions, cytoskeletal organization and migration through modulation of p190 RhoGAP and Rho GTPase activity. Experimental Cell Research. 295: 488-96. PMID 15093746 DOI: 10.1016/j.yexcr.2004.01.026  0.8
2004 Barker TH, Pallero MA, MacEwen MW, Tilden SG, Woods A, Murphy-Ullrich JE, Hagood JS. Thrombospondin-1-induced focal adhesion disassembly in fibroblasts requires Thy-1 surface expression, lipid raft integrity, and Src activation. The Journal of Biological Chemistry. 279: 23510-6. PMID 15033989 DOI: 10.1074/jbc.M402169200  0.8
2001 Barker TH, Fuller GM, Klinger MM, Feldman DS, Hagood JS. Modification of fibrinogen with poly(ethylene glycol) and its effects on fibrin clot characteristics. Journal of Biomedical Materials Research. 56: 529-35. PMID 11400130 DOI: 10.1002/1097-4636(20010915)56:4<529::AID-JBM1124>3.0.CO;2-2  0.8
2001 Barker TH, Klinger MM, Feldman DS, Fuller GM, Hagood JS. Spectrophotometric analysis for determining the average number of poly(ethylene) glycol molecules on PEGylated proteins utilizing a protein digestion step. Analytical Biochemistry. 290: 382-5. PMID 11237345 DOI: 10.1006/abio.2001.4987  0.8
1999 Wang Z, Barker TH, Fuller GM. Alcohol at moderate levels decreases fibrinogen expression in vivo and in vitro. Alcoholism, Clinical and Experimental Research. 23: 1927-32. PMID 10630612  0.8
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