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Lijuan Yuan, Ph.D. - Publications

Affiliations: 
2007- Department of Biomedical Sciences and Pathobiology Virginia Polytechnic Institute and State University, Blacksburg, VA, United States 
Area:
Immunology, Microbiology Biology
Website:
http://www.vetmed.vt.edu/org/dbsp/faculty/yuan.asp

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nyblade C, Zhou P, Frazier M, Frazier A, Hensley C, Fantasia-Davis A, Shahrudin S, Hoffer M, Agbemabiese CA, LaRue L, Barro M, Patton JT, Parreño V, Yuan L. Human Rotavirus Replicates in Salivary Glands and Primes Immune Responses in Facial and Intestinal Lymphoid Tissues of Gnotobiotic Pigs. Viruses. 15. PMID 37766270 DOI: 10.3390/v15091864  0.738
2023 Giri-Rachman EA, Irasonia Tan M, Ramesh A, Fajar PA, Nurul Ilmi A, Retnoningrum DS, Hertadi R, Irawan A, Wojciechowska GEP, Yuan L. Development of Chimeric Hepatitis B (HBV) - Norovirus (NoV) P particle as candidate vaccine against Hepatitis B and norovirus infection. Vaccine: X. 14: 100354. PMID 37519778 DOI: 10.1016/j.jvacx.2023.100354  0.783
2023 He Y, Xu Z, Kasputis T, Zhao X, Ibañez I, Pavan F, Bok M, Malito JP, Parreno V, Yuan L, Wright RC, Chen J. Development of Nanobody-Displayed Whole-Cell Biosensors for the Colorimetric Detection of SARS-CoV-2. Acs Applied Materials & Interfaces. PMID 37489943 DOI: 10.1021/acsami.3c05900  0.62
2023 Hensley C, Nyblade C, Zhou P, Parreño V, Ramesh A, Frazier A, Frazier M, Garrison S, Fantasia-Davis A, Cai R, Huang PW, Xia M, Tan M, Yuan L. Combined Live Oral Priming and Intramuscular Boosting Regimen with Rotarix and a Nanoparticle-Based Trivalent Rotavirus Vaccine Evaluated in Gnotobiotic Pig Models of G4P[6] and G1P[8] Human Rotavirus Infection. Vaccines. 11. PMID 37243031 DOI: 10.3390/vaccines11050927  0.842
2023 Pavan MF, Bok M, Juan RBS, Malito JP, Marcoppido GA, Franco DR, Militello DA, Schammas JM, Bari S, Stone WB, López K, Porier DL, Muller J, Auguste AJ, Yuan L, et al. Nanobodies against SARS-CoV-2 reduced virus load in the brain of challenged mice and neutralized Wuhan, Delta and Omicron Variants. Biorxiv : the Preprint Server For Biology. PMID 36993215 DOI: 10.1101/2023.03.14.532528  0.652
2022 Nyblade C, Hensley C, Parreño V, Zhou P, Frazier M, Frazier A, Ramesh A, Lei S, Degiuseppe JI, Tan M, Yuan L. A New Gnotobiotic Pig Model of P[6] Human Rotavirus Infection and Disease for Preclinical Evaluation of Rotavirus Vaccines. Viruses. 14. PMID 36560807 DOI: 10.3390/v14122803  0.842
2022 Artman C, Idegwu N, Brumfield KD, Lai K, Hauta S, Falzarano D, Parreño V, Yuan L, Geyer JD, Goepp JG. Feasibility of Polyclonal Avian Immunoglobulins (IgY) as Prophylaxis against Human Norovirus Infection. Viruses. 14. PMID 36366469 DOI: 10.3390/v14112371  0.745
2022 Parreno V, Bai M, Liu F, Jing J, Olney E, Li G, Wen K, Yang X, Castellucc TB, Kocher JF, Zhou X, Yuan L. Probiotic as Adjuvant Significantly Improves Protection of the Lanzhou Trivalent Rotavirus Vaccine against Heterologous Challenge in a Gnotobiotic Pig Model of Human Rotavirus Infection and Disease. Vaccines. 10. PMID 36146607 DOI: 10.3390/vaccines10091529  0.853
2022 Nyblade C, Parreno V, Zhou P, Hensley C, Oakes V, Mahsoub HM, Kiley K, Frazier M, Frazier A, Zhang Y, Feng H, Yuan L. Establishment of a gnotobiotic pig model of Clostridioides difficile infection and disease. Gut Pathogens. 14: 22. PMID 35668452 DOI: 10.1186/s13099-022-00496-y  0.7
2021 Ahmed S, Travis SD, Díaz-Bahamonde FV, Porter DDL, Henry SN, Mykins J, Ravipati A, Booker A, Ju J, Ding H, Ramesh AK, Pickrell AM, Wang M, LaConte S, Howell BR, ... Yuan L, et al. Early Influences of Microbiota on White Matter Development in Germ-Free Piglets. Frontiers in Cellular Neuroscience. 15: 807170. PMID 35027884 DOI: 10.3389/fncel.2021.807170  0.739
2021 Kocher J, Castellucci TB, Wen K, Li G, Yang X, Lei S, Jiang X, Yuan L. Simvastatin Reduces Protection and Intestinal T Cell Responses Induced by a Norovirus P Particle Vaccine in Gnotobiotic Pigs. Pathogens (Basel, Switzerland). 10. PMID 34357979 DOI: 10.3390/pathogens10070829  0.787
2021 Hensley C, Zhou P, Schnur S, Mahsoub HM, Liang Y, Wang MX, Page C, Yuan L, Bronshtein V. Thermostable, Dissolvable Buccal Film Rotavirus Vaccine Is Highly Effective in Neonatal Gnotobiotic Pig Challenge Model. Vaccines. 9. PMID 33946555 DOI: 10.3390/vaccines9050437  0.416
2020 Ramesh AK, Parreño V, Schmidt PJ, Lei S, Zhong W, Jiang X, Emelko MB, Yuan L. Evaluation of the 50% Infectious Dose of Human Norovirus Cin-2 in Gnotobiotic Pigs: A Comparison of Classical and Contemporary Methods for Endpoint Estimation. Viruses. 12. PMID 32872283 DOI: 10.3390/V12090955  0.79
2020 Yuan L, Hensley C, Mahsoub HM, Ramesh AK, Zhou P. Microbiota in viral infection and disease in humans and farm animals. Progress in Molecular Biology and Translational Science. 171: 15-60. PMID 32475521 DOI: 10.1016/Bs.Pmbts.2020.04.005  0.811
2020 Mahsoub HM, Yuan L, Pierson FW. Turkey adenovirus 3, a siadenovirus, uses sialic acid on -linked glycoproteins as a cellular receptor. The Journal of General Virology. PMID 32459612 DOI: 10.1099/Jgv.0.001429  0.354
2019 Fix J, Chandrashekhar K, Perez J, Bucardo F, Hudgens MG, Yuan L, Twitchell E, Azcarate-Peril MA, Vilchez S, Becker-Dreps S. Association between Gut Microbiome Composition and Rotavirus Vaccine Response among Nicaraguan Infants. The American Journal of Tropical Medicine and Hygiene. PMID 31802728 DOI: 10.4269/Ajtmh.19-0355  0.827
2019 Lei S, Twitchell EL, Ramesh AK, Bui T, Majette E, Tin CM, Avery R, Arango-Argoty G, Zhang L, Becker-Dreps S, Azcarate-Peril MA, Jiang X, Yuan L. Enhanced GII.4 human norovirus infection in gnotobiotic pigs transplanted with a human gut microbiota. The Journal of General Virology. PMID 31596195 DOI: 10.1099/Jgv.0.001336  0.807
2019 Zambrana LE, McKeen S, Ibrahim H, Zarei I, Borresen EC, Doumbia L, Boré A, Cissoko A, Douyon S, Koné K, Perez J, Perez C, Hess A, Abdo Z, Sangaré L, ... ... Yuan L, et al. Rice bran supplementation modulates growth, microbiota and metabolome in weaning infants: a clinical trial in Nicaragua and Mali. Scientific Reports. 9: 13919. PMID 31558739 DOI: 10.1038/S41598-019-50344-4  0.322
2018 Yugo DM, Heffron CL, Ryu J, Uh K, Subramaniam S, Matzinger SR, Overend C, Cao D, Kenney SP, Sooryanarain H, Cecere T, LeRoith T, Yuan L, Jue N, Clark-Deener S, et al. Infection dynamics of hepatitis E virus in wild-type and immunoglobulin heavy chain knockout J (-/-) gnotobiotic piglets. Journal of Virology. PMID 30111571 DOI: 10.1128/Jvi.01208-18  0.398
2017 Tin CM, Yuan L, Dexter RJ, Parra GI, Bui T, Green KY, Sosnovtsev SV. A Luciferase Immunoprecipitation System (LIPS) assay for profiling human norovirus antibodies. Journal of Virological Methods. PMID 28673856 DOI: 10.1016/J.Jviromet.2017.06.017  0.368
2017 Cao D, Cao QM, Subramaniam S, Yugo DM, Heffron CL, Rogers AJ, Kenney SP, Tian D, Matzinger SR, Overend C, Catanzaro N, LeRoith T, Wang H, Piñeyro P, Lindstrom N, ... ... Yuan L, et al. Pig model mimicking chronic hepatitis E virus infection in immunocompromised patients to assess immune correlates during chronicity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630341 DOI: 10.1073/Pnas.1705446114  0.421
2017 Nealon NJ, Yuan L, Yang X, Ryan EP. Rice Bran and Probiotics Alter the Porcine Large Intestine and Serum Metabolomes for Protection against Human Rotavirus Diarrhea. Frontiers in Microbiology. 8: 653. PMID 28484432 DOI: 10.3389/Fmicb.2017.00653  0.722
2017 Bui T, Li G, Kim I, Wen K, Twitchell EL, Hualei S, Ramesh AK, Weiss MD, Yang X, Glark-Deener SG, Choy RK, Yuan L. Effects of Racecadotril on Weight Loss and Diarrhea Due to Human Rotavirus in Neonatal Gnotobiotic Pigs (Sus scrofa domesticus). Comparative Medicine. 67: 157-164. PMID 28381316  0.798
2017 Sheng J, Lei S, Yuan L, Feng X. Cell-free protein synthesis of norovirus virus-like particles Rsc Advances. 7: 28837-28840. DOI: 10.1039/C7Ra03742B  0.692
2016 Becker-Dreps S, Vilchez S, Bucardo F, Twitchell E, Choi WS, Hudgens MG, Perez J, Yuan L. The Association Between Fecal Biomarkers of Environmental Enteropathy and Rotavirus Vaccine Response in Nicaraguan Infants. The Pediatric Infectious Disease Journal. PMID 27977553 DOI: 10.1097/Inf.0000000000001457  0.825
2016 Lei S, Ramesh A, Twitchell E, Wen K, Bui T, Weiss M, Yang X, Kocher J, Li G, Giri-Rachman E, Trang NV, Jiang X, Ryan EP, Yuan L. High Protective Efficacy of Probiotics and Rice Bran against Human Norovirus Infection and Diarrhea in Gnotobiotic Pigs. Frontiers in Microbiology. 7: 1699. PMID 27853451 DOI: 10.3389/Fmicb.2016.01699  0.819
2016 Mahsoub HM, Evans NP, Beach NM, Yuan L, Zimmerman K, Pierson FW. Real-time PCR-based infectivity assay for the titration of turkey hemorrhagic enteritis virus, an adenovirus, in live vaccines. Journal of Virological Methods. PMID 27829121 DOI: 10.1016/J.Jviromet.2016.11.002  0.496
2016 Twitchell EL, Tin C, Wen K, Zhang H, Becker-Dreps S, Azcarate-Peril MA, Vilchez S, Li G, Ramesh A, Weiss M, Lei S, Bui T, Yang X, Schultz-Cherry S, Yuan L. Modeling human enteric dysbiosis and rotavirus immunity in gnotobiotic pigs. Gut Pathogens. 8: 51. PMID 27826359 DOI: 10.1186/S13099-016-0136-Y  0.814
2016 Wang H, Gao K, Wen K, Allen IC, Li G, Zhang W, Kocher J, Yang X, Giri-Rachman E, Li GH, Clark-Deener S, Yuan L. Lactobacillus rhamnosus GG modulates innate signaling pathway and cytokine responses to rotavirus vaccine in intestinal mononuclear cells of gnotobiotic pigs transplanted with human gut microbiota. Bmc Microbiology. 16: 109. PMID 27301272 DOI: 10.1186/S12866-016-0727-2  0.826
2016 Lei S, Ryu J, Wen K, Twitchell E, Bui T, Ramesh A, Weiss M, Li G, Samuel H, Clark-Deener S, Jiang X, Lee K, Yuan L. Increased and prolonged human norovirus infection in RAG2/IL2RG deficient gnotobiotic pigs with severe combined immunodeficiency. Scientific Reports. 6: 25222. PMID 27118081 DOI: 10.1038/Srep25222  0.799
2016 Lei S, Samuel H, Twitchell E, Bui T, Ramesh A, Wen K, Weiss M, Li G, Yang X, Jiang X, Yuan L. Enterobacter cloacae inhibits human norovirus infectivity in gnotobiotic pigs. Scientific Reports. 6: 25017. PMID 27113278 DOI: 10.1038/Srep25017  0.783
2016 Wen K, Bui T, Weiss M, Li G, Kocher J, Yang X, Jobst PM, Vaught T, Ramsoondar J, Ball S, Clark-Deener S, Ayares D, Yuan L. B-Cell-Deficient and CD8 T-Cell-Depleted Gnotobiotic Pigs for the Study of Human Rotavirus Vaccine-Induced Protective Immune Responses. Viral Immunology. PMID 26824402 DOI: 10.1089/Vim.2015.0105  0.819
2015 Kocher J, Yuan L. Norovirus vaccines and potential antinorovirus drugs: recent advances and future perspectives. Future Virology. 10: 899-913. PMID 26568768 DOI: 10.2217/Fvl.15.57  0.683
2015 Yang X, Twitchell E, Li G, Wen K, Weiss M, Kocher J, Lei S, Ramesh A, Ryan EP, Yuan L. High protective efficacy of rice bran against human rotavirus diarrhea via enhancing probiotic growth, gut barrier function, and innate immunity. Scientific Reports. 5: 15004. PMID 26459937 DOI: 10.1038/Srep15004  0.792
2015 Wen X, Cao D, Jones RW, Hoshino Y, Yuan L. Tandem Truncated Rotavirus VP8* Subunit Protein with T cell Epitope as Non-replicating Parenteral Vaccine is Highly Immunogenic. Human Vaccines & Immunotherapeutics. 0. PMID 26091081 DOI: 10.1080/21645515.2015.1054583  0.674
2015 Ma Y, Wen X, Hoshino Y, Yuan L. Cloning and nucleotide sequence analyses of 11 genome segments of two American and one British equine rotavirus strains. Veterinary Microbiology. 176: 172-8. PMID 25631250 DOI: 10.1016/J.Vetmic.2015.01.008  0.59
2015 Wen K, Liu F, Li G, Bai M, Kocher J, Yang X, Wang H, Clark-Deener S, Yuan L. Lactobacillus rhamnosus GG Dosage Affects the Adjuvanticity and Protection Against Rotavirus Diarrhea in Gnotobiotic Pigs. Journal of Pediatric Gastroenterology and Nutrition. 60: 834-43. PMID 25564808 DOI: 10.1097/Mpg.0000000000000694  0.8
2014 Yang X, Li G, Wen K, Bui T, Liu F, Kocher J, Jortner BS, Vonck M, Pelzer K, Deng J, Zhu R, Li Y, Qian Y, Yuan L. A neonatal gnotobiotic pig model of human enterovirus 71 infection and associated immune responses. Emerging Microbes & Infections. 3: e35. PMID 26038741 DOI: 10.1038/Emi.2014.35  0.839
2014 Zhang H, Wang H, Shepherd M, Wen K, Li G, Yang X, Kocher J, Giri-Rachman E, Dickerman A, Settlage R, Yuan L. Probiotics and virulent human rotavirus modulate the transplanted human gut microbiota in gnotobiotic pigs. Gut Pathogens. 6: 39. PMID 25349634 DOI: 10.1186/S13099-014-0039-8  0.819
2014 Yang X, Wen K, Tin C, Li G, Wang H, Kocher J, Pelzer K, Ryan E, Yuan L. Dietary rice bran protects against rotavirus diarrhea and promotes Th1-type immune responses to human rotavirus vaccine in gnotobiotic pigs. Clinical and Vaccine Immunology : Cvi. 21: 1396-403. PMID 25080551 DOI: 10.1128/Cvi.00210-14  0.847
2014 Wen X, Wen K, Cao D, Li G, Jones RW, Li J, Szu S, Hoshino Y, Yuan L. Inclusion of a universal tetanus toxoid CD4(+) T cell epitope P2 significantly enhanced the immunogenicity of recombinant rotavirus ΔVP8* subunit parenteral vaccines. Vaccine. 32: 4420-7. PMID 24962749 DOI: 10.1016/J.Vaccine.2014.06.060  0.713
2014 Kocher J, Bui T, Giri-Rachman E, Wen K, Li G, Yang X, Liu F, Tan M, Xia M, Zhong W, Jiang X, Yuan L. Intranasal P particle vaccine provided partial cross-variant protection against human GII.4 norovirus diarrhea in gnotobiotic pigs. Journal of Virology. 88: 9728-43. PMID 24920797 DOI: 10.1128/Jvi.01249-14  0.84
2014 Wen K, Tin C, Wang H, Yang X, Li G, Giri-Rachman E, Kocher J, Bui T, Clark-Deener S, Yuan L. Probiotic Lactobacillus rhamnosus GG enhanced Th1 cellular immunity but did not affect antibody responses in a human gut microbiota transplanted neonatal gnotobiotic pig model. Plos One. 9: e94504. PMID 24722168 DOI: 10.1371/Journal.Pone.0094504  0.844
2014 Liu F, Wen K, Li G, Yang X, Kocher J, Bui T, Jones D, Pelzer K, Clark-Deener S, Yuan L. Dual functions of Lactobacillus acidophilus NCFM as protection against rotavirus diarrhea. Journal of Pediatric Gastroenterology and Nutrition. 58: 169-76. PMID 24126832 DOI: 10.1097/Mpg.0000000000000197  0.824
2013 Liu F, Li G, Wen K, Wu S, Zhang Y, Bui T, Yang X, Kocher J, Sun J, Jortner B, Yuan L. Lactobacillus rhamnosus GG on rotavirus-induced injury of ileal epithelium in gnotobiotic pigs. Journal of Pediatric Gastroenterology and Nutrition. 57: 750-8. PMID 24280990 DOI: 10.1097/Mpg.0B013E3182A356E1  0.808
2013 Wu S, Yuan L, Zhang Y, Liu F, Li G, Wen K, Kocher J, Yang X, Sun J. Probiotic Lactobacillus rhamnosus GG mono-association suppresses human rotavirus-induced autophagy in the gnotobiotic piglet intestine. Gut Pathogens. 5: 22. PMID 23924832 DOI: 10.1186/1757-4749-5-22  0.798
2013 Bui T, Kocher J, Li Y, Wen K, Li G, Liu F, Yang X, LeRoith T, Tan M, Xia M, Zhong W, Jiang X, Yuan L. Median infectious dose of human norovirus GII.4 in gnotobiotic pigs is decreased by simvastatin treatment and increased by age. The Journal of General Virology. 94: 2005-16. PMID 23804568 DOI: 10.1099/Vir.0.054080-0  0.848
2013 Viladomiu M, Hontecillas R, Yuan L, Lu P, Bassaganya-Riera J. Nutritional protective mechanisms against gut inflammation. The Journal of Nutritional Biochemistry. 24: 929-39. PMID 23541470 DOI: 10.1016/J.Jnutbio.2013.01.006  0.348
2013 Wu S, Liu F, Zhang Y, Li G, Wen K, Yuan L, Sun J. Tu1990 Probiotic LGG Mono-Association Suppresses Virus-Induced Autophagy in Gnotobiotic Swine Intestine Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63346-6  0.356
2012 Overend C, Yuan L, Peccoud J. The synthetic futures of vesicular stomatitis virus. Trends in Biotechnology. 30: 497-8. PMID 22789133 DOI: 10.1016/J.Tibtech.2012.06.002  0.357
2012 Wen K, Li G, Yang X, Bui T, Bai M, Liu F, Kocher J, Yuan L. CD4+ CD25- FoxP3+ regulatory cells are the predominant responding regulatory T cells after human rotavirus infection or vaccination in gnotobiotic pigs. Immunology. 137: 160-71. PMID 22716916 DOI: 10.1111/J.1365-2567.2012.03617.X  0.793
2012 Azevedo MS, Zhang W, Wen K, Gonzalez AM, Saif LJ, Yousef AE, Yuan L. Lactobacillus acidophilus and Lactobacillus reuteri modulate cytokine responses in gnotobiotic pigs infected with human rotavirus. Beneficial Microbes. 3: 33-42. PMID 22348907 DOI: 10.3920/Bm2011.0041  0.547
2012 Wen K, Bui T, Li G, Liu F, Li Y, Kocher J, Yuan L. Characterization of immune modulating functions of γδ T cell subsets in a gnotobiotic pig model of human rotavirus infection. Comparative Immunology, Microbiology and Infectious Diseases. 35: 289-301. PMID 22333156 DOI: 10.1016/J.Cimid.2012.01.010  0.608
2012 Wen K, Li G, Bui T, Liu F, Li Y, Kocher J, Lin L, Yang X, Yuan L. High dose and low dose Lactobacillus acidophilus exerted differential immune modulating effects on T cell immune responses induced by an oral human rotavirus vaccine in gnotobiotic pigs. Vaccine. 30: 1198-207. PMID 22178726 DOI: 10.1016/J.Vaccine.2011.11.107  0.815
2011 Wen K, Li G, Zhang W, Azevedo MS, Saif LJ, Liu F, Bui T, Yousef A, Yuan L. Development of γδ T cell subset responses in gnotobiotic pigs infected with human rotaviruses and colonized with probiotic lactobacilli. Veterinary Immunology and Immunopathology. 141: 267-75. PMID 21489639 DOI: 10.1016/J.Vetimm.2011.03.016  0.561
2010 Liu F, Li G, Wen K, Bui T, Cao D, Zhang Y, Yuan L. Porcine small intestinal epithelial cell line (IPEC-J2) of rotavirus infection as a new model for the study of innate immune responses to rotaviruses and probiotics. Viral Immunology. 23: 135-49. PMID 20373994 DOI: 10.1089/Vim.2009.0088  0.451
2010 Azevedo MS, Gonzalez AM, Yuan L, Jeong KI, Iosef C, Van Nguyen T, Lovgren-Bengtsson K, Morein B, Saif LJ. An oral versus intranasal prime/boost regimen using attenuated human rotavirus or VP2 and VP6 virus-like particles with immunostimulating complexes influences protection and antibody-secreting cell responses to rotavirus in a neonatal gnotobiotic pig model. Clinical and Vaccine Immunology : Cvi. 17: 420-8. PMID 20107005 DOI: 10.1128/Cvi.00395-09  0.678
2010 Matthijnssens J, Taraporewala ZF, Yang H, Rao S, Yuan L, Cao D, Hoshino Y, Mertens PP, Carner GR, McNeal M, Sestak K, Van Ranst M, Patton JT. Simian rotaviruses possess divergent gene constellations that originated from interspecies transmission and reassortment. Journal of Virology. 84: 2013-26. PMID 19939934 DOI: 10.1128/Jvi.02081-09  0.623
2009 Yuan L, Honma S, Kim I, Kapikian AZ, Hoshino Y. Resistance to rotavirus infection in adult volunteers challenged with a virulent G1P1A[8] virus correlated with serum immunoglobulin G antibodies to homotypic viral proteins 7 and 4. The Journal of Infectious Diseases. 200: 1443-51. PMID 19785527 DOI: 10.1086/606116  0.653
2009 Cao D, Igboeli B, Yuan L, Kapikian AZ, Ayers JL, Abinanti FR, Hoshino Y. A longitudinal cohort study in calves evaluated for rotavirus infections from 1 to 12 months of age by sequential serological assays. Archives of Virology. 154: 755-63. PMID 19343476 DOI: 10.1007/S00705-009-0331-Y  0.636
2009 Wen K, Azevedo MS, Gonzalez A, Zhang W, Saif LJ, Li G, Yousef A, Yuan L. Toll-like receptor and innate cytokine responses induced by lactobacilli colonization and human rotavirus infection in gnotobiotic pigs. Veterinary Immunology and Immunopathology. 127: 304-15. PMID 19054578 DOI: 10.1016/J.Vetimm.2008.10.322  0.561
2008 Zhang W, Azevedo MS, Wen K, Gonzalez A, Saif LJ, Li G, Yousef AE, Yuan L. Probiotic Lactobacillus acidophilus enhances the immunogenicity of an oral rotavirus vaccine in gnotobiotic pigs. Vaccine. 26: 3655-61. PMID 18524434 DOI: 10.1016/J.Vaccine.2008.04.070  0.672
2008 Yuan L, Wen K, Azevedo MS, Gonzalez AM, Zhang W, Saif LJ. Virus-specific intestinal IFN-gamma producing T cell responses induced by human rotavirus infection and vaccines are correlated with protection against rotavirus diarrhea in gnotobiotic pigs. Vaccine. 26: 3322-31. PMID 18456375 DOI: 10.1016/J.Vaccine.2008.03.085  0.656
2008 Zhang W, Azevedo MS, Gonzalez AM, Saif LJ, Van Nguyen T, Wen K, Yousef AE, Yuan L. Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease. Veterinary Immunology and Immunopathology. 122: 175-81. PMID 18023882 DOI: 10.1016/J.Vetimm.2007.10.003  0.618
2008 Zhang W, Wen K, Azevedo MS, Gonzalez A, Saif LJ, Li G, Yousef AE, Yuan L. Lactic acid bacterial colonization and human rotavirus infection influence distribution and frequencies of monocytes/macrophages and dendritic cells in neonatal gnotobiotic pigs. Veterinary Immunology and Immunopathology. 121: 222-31. PMID 18006076 DOI: 10.1016/J.Vetimm.2007.10.001  0.58
2007 Nguyen TV, Yuan L, Azevedo MS, Jeong KI, Gonzalez AM, Saif LJ. Transfer of maternal cytokines to suckling piglets: in vivo and in vitro models with implications for immunomodulation of neonatal immunity. Veterinary Immunology and Immunopathology. 117: 236-48. PMID 17403542 DOI: 10.1016/J.Vetimm.2007.02.013  0.476
2006 Nguyen TV, Yuan L, Azevedo MS, Jeong KI, Gonzalez AM, Iosef C, Lovgren-Bengtsson K, Morein B, Lewis P, Saif LJ. High titers of circulating maternal antibodies suppress effector and memory B-cell responses induced by an attenuated rotavirus priming and rotavirus-like particle-immunostimulating complex boosting vaccine regimen. Clinical and Vaccine Immunology : Cvi. 13: 475-85. PMID 16603615 DOI: 10.1128/Cvi.13.4.475-485.2006  0.665
2006 Nguyen TV, Yuan L, Azevedo MS, Jeong KI, Gonzalez AM, Iosef C, Lovgren-Bengtsson K, Morein B, Lewis P, Saif LJ. Low titer maternal antibodies can both enhance and suppress B cell responses to a combined live attenuated human rotavirus and VLP-ISCOM vaccine. Vaccine. 24: 2302-16. PMID 16361002 DOI: 10.1016/J.Vaccine.2005.11.043  0.651
2006 Azevedo MS, Yuan L, Pouly S, Gonzales AM, Jeong KI, Nguyen TV, Saif LJ. Cytokine responses in gnotobiotic pigs after infection with virulent or attenuated human rotavirus. Journal of Virology. 80: 372-82. PMID 16352562 DOI: 10.1128/Jvi.80.1.372-382.2006  0.537
2005 Yuan L, Azevedo MS, Gonzalez AM, Jeong KI, Van Nguyen T, Lewis P, Iosef C, Herrmann JE, Saif LJ. Mucosal and systemic antibody responses and protection induced by a prime/boost rotavirus-DNA vaccine in a gnotobiotic pig model. Vaccine. 23: 3925-36. PMID 15917114 DOI: 10.1016/J.Vaccine.2005.03.009  0.622
2005 Azevedo MS, Yuan L, Jeong KI, Gonzalez A, Nguyen TV, Pouly S, Gochnauer M, Zhang W, Azevedo A, Saif LJ. Viremia and nasal and rectal shedding of rotavirus in gnotobiotic pigs inoculated with Wa human rotavirus. Journal of Virology. 79: 5428-36. PMID 15827157 DOI: 10.1128/Jvi.79.9.5428-5436.2005  0.621
2005 Yuan L, Honma S, Ishida S, Yan X, Kapikian AZ, Hoshino Y. Erratum to “Species-specific but not genotype-specific primary and secondary isotype-specific NSP4 antibody responses in gnotobiotic calves and piglets infected with homologous host bovine (NSP4[A]) or porcine (NSP4[B]) rotavirus ” [Virology 330 (2004) 92–104] Virology. 331: 471-472. DOI: 10.1016/J.Virol.2004.11.002  0.644
2004 Yuan L, Honma S, Ishida S, Yan XY, Kapikian AZ, Hoshino Y. Species-specific but not genotype-specific primary and secondary isotype-specific NSP4 antibody responses in gnotobiotic calves and piglets infected with homologous host bovine (NSP4[A]) or porcine (NSP4[B]) rotavirus. Virology. 330: 92-104. PMID 15527837 DOI: 10.1016/J.Virol.2004.09.021  0.69
2004 Parreño V, Béjar C, Vagnozzi A, Barrandeguy M, Costantini V, Craig MI, Yuan L, Hodgins D, Saif L, Fernández F. Modulation by colostrum-acquired maternal antibodies of systemic and mucosal antibody responses to rotavirus in calves experimentally challenged with bovine rotavirus. Veterinary Immunology and Immunopathology. 100: 7-24. PMID 15182992 DOI: 10.1016/J.Vetimm.2004.02.007  0.588
2004 Yuan L, Ishida S, Honma S, Patton JT, Hodgins DC, Kapikian AZ, Hoshino Y. Homotypic and heterotypic serum isotype-specific antibody responses to rotavirus nonstructural protein 4 and viral protein (VP) 4, VP6, and VP7 in infants who received selected live oral rotavirus vaccines. The Journal of Infectious Diseases. 189: 1833-45. PMID 15122520 DOI: 10.1086/383416  0.687
2004 Azevedo MS, Yuan L, Iosef C, Chang KO, Kim Y, Nguyen TV, Saif LJ. Magnitude of serum and intestinal antibody responses induced by sequential replicating and nonreplicating rotavirus vaccines in gnotobiotic pigs and correlation with protection. Clinical and Diagnostic Laboratory Immunology. 11: 12-20. PMID 14715539 DOI: 10.1128/Cdli.11.1.12-20.2004  0.728
2003 Nguyen TV, Iosef C, Jeong K, Kim Y, Chang KO, Lovgren-Bengtsson K, Morein B, Azevedo MS, Lewis P, Nielsen P, Yuan L, Saif LJ. Protection and antibody responses to oral priming by attenuated human rotavirus followed by oral boosting with 2/6-rotavirus-like particles with immunostimulating complexes in gnotobiotic pigs. Vaccine. 21: 4059-70. PMID 12922143 DOI: 10.1016/S0264-410X(03)00267-6  0.691
2003 Yuan L, Saif LJ. II, 14. Rotavirus-like particle vaccines evaluated in a pig model of human rotavirus diarrhea and in cattle Perspectives in Medical Virology. 9: 357-368. DOI: 10.1016/S0168-7069(03)09021-9  0.639
2002 Yuan L, Saif LJ. Induction of mucosal immune responses and protection against enteric viruses: rotavirus infection of gnotobiotic pigs as a model. Veterinary Immunology and Immunopathology. 87: 147-60. PMID 12072229 DOI: 10.1016/S0165-2427(02)00046-6  0.695
2002 Iosef C, Van Nguyen T, Jeong Ki, Bengtsson K, Morein B, Kim Y, Chang KO, Azevedo MS, Yuan L, Nielsen P, Saif LJ. Systemic and intestinal antibody secreting cell responses and protection in gnotobiotic pigs immunized orally with attenuated Wa human rotavirus and Wa 2/6-rotavirus-like-particles associated with immunostimulating complexes. Vaccine. 20: 1741-53. PMID 11906761 DOI: 10.1016/S0264-410X(02)00031-2  0.748
2001 Yuan L, Iosef C, Azevedo MS, Kim Y, Qian Y, Geyer A, Nguyen TV, Chang KO, Saif LJ. Protective immunity and antibody-secreting cell responses elicited by combined oral attenuated Wa human rotavirus and intranasal Wa 2/6-VLPs with mutant Escherichia coli heat-labile toxin in gnotobiotic pigs. Journal of Virology. 75: 9229-38. PMID 11533185 DOI: 10.1128/Jvi.75.19.9229-9238.2001  0.756
2001 Chang KO, Vandal OH, Yuan L, Hodgins DC, Saif LJ. Antibody-secreting cell responses to rotavirus proteins in gnotobiotic pigs inoculated with attenuated or virulent human rotavirus. Journal of Clinical Microbiology. 39: 2807-13. PMID 11473996 DOI: 10.1128/Jcm.39.8.2807-2813.2001  0.616
2001 Yuan L, Geyer A, Saif LJ. Short-term immunoglobulin A B-cell memory resides in intestinal lymphoid tissues but not in bone marrow of gnotobiotic pigs inoculated with Wa human rotavirus. Immunology. 103: 188-98. PMID 11412306 DOI: 10.1046/J.1365-2567.2001.01229.X  0.538
2000 Yuan L, Geyer A, Hodgins DC, Fan Z, Qian Y, Chang KO, Crawford SE, Parreño V, Ward LA, Estes MK, Conner ME, Saif LJ. Intranasal administration of 2/6-rotavirus-like particles with mutant Escherichia coli heat-labile toxin (LT-R192G) induces antibody-secreting cell responses but not protective immunity in gnotobiotic pigs. Journal of Virology. 74: 8843-53. PMID 10982326 DOI: 10.1128/Jvi.74.19.8843-8853.2000  0.639
1999 Parreño V, Hodgins DC, de Arriba L, Kang SY, Yuan L, Ward LA, Tô TL, Saif LJ. Serum and intestinal isotype antibody responses to Wa human rotavirus in gnotobiotic pigs are modulated by maternal antibodies. The Journal of General Virology. 80: 1417-28. PMID 10374959 DOI: 10.1099/0022-1317-80-6-1417  0.608
1999 Hodgins DC, Kang SY, deArriba L, Parreño V, Ward LA, Yuan L, To T, Saif LJ. Effects of maternal antibodies on protection and development of antibody responses to human rotavirus in gnotobiotic pigs. Journal of Virology. 73: 186-97. PMID 9847321 DOI: 10.1128/Jvi.73.1.186-197.1999  0.772
1998 Tô TL, Ward LA, Yuan L, Saif LJ. Serum and intestinal isotype antibody responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease. The Journal of General Virology. 79: 2661-72. PMID 9820141 DOI: 10.1099/0022-1317-79-11-2661  0.62
1998 Yuan L, Kang SY, Ward LA, To TL, Saif LJ. Antibody-secreting cell responses and protective immunity assessed in gnotobiotic pigs inoculated orally or intramuscularly with inactivated human rotavirus. Journal of Virology. 72: 330-8. PMID 9420231 DOI: 10.1128/Jvi.72.1.330-338.1998  0.63
1997 Saif L, Yuan L, Ward L, To T. Comparative studies of the pathogenesis, antibody immune responses, and homologous protection to porcine and human rotaviruses in gnotobiotic piglets. Advances in Experimental Medicine and Biology. 412: 397-403. PMID 9192046 DOI: 10.1007/978-1-4899-1828-4_62  0.665
1996 Saif LJ, Ward LA, Yuan L, Rosen BI, To TL. The gnotobiotic piglet as a model for studies of disease pathogenesis and immunity to human rotaviruses. Archives of Virology. Supplementum. 12: 153-61. PMID 9015112 DOI: 10.1007/978-3-7091-6553-9_17  0.67
1996 Ward LA, Rosen BI, Yuan L, Saif LJ. Pathogenesis of an attenuated and a virulent strain of group A human rotavirus in neonatal gnotobiotic pigs. The Journal of General Virology. 77: 1431-41. PMID 8757984 DOI: 10.1099/0022-1317-77-7-1431  0.583
1996 Ward LA, Yuan L, Rosen BI, Tô TL, Saif LJ. Development of mucosal and systemic lymphoproliferative responses and protective immunity to human group A rotaviruses in a gnotobiotic pig model. Clinical and Diagnostic Laboratory Immunology. 3: 342-50. PMID 8705681 DOI: 10.1128/Cdli.3.3.342-350.1996  0.609
1996 Yuan L, Ward LA, Rosen BI, To TL, Saif LJ. Systematic and intestinal antibody-secreting cell responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease. Journal of Virology. 70: 3075-83. PMID 8627786 DOI: 10.1128/Jvi.70.5.3075-3083.1996  0.678
1994 Yuan L. Measles outbreak in 31 schools: Risk factors for vaccine failure and evaluation of a selective revaccination strategy Cmaj. 150: 1093-1098. PMID 8137189  0.31
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