Year |
Citation |
Score |
2023 |
Lee J, Lim K, Kim A, Mok YG, Chung E, Cho SI, Lee JM, Kim JS. Prime editing with genuine Cas9 nickases minimizes unwanted indels. Nature Communications. 14: 1786. PMID 36997524 DOI: 10.1038/s41467-023-37507-8 |
0.3 |
|
2023 |
Kim YH, Kim N, Okafor I, Choi S, Min S, Lee J, Bae SM, Choi K, Choi J, Harihar V, Kim Y, Kim JS, Kleinstiver BP, Lee JK, Ha T, et al. Sniper2L is a high-fidelity Cas9 variant with high activity. Nature Chemical Biology. PMID 36894722 DOI: 10.1038/s41589-023-01279-5 |
0.304 |
|
2020 |
Kim D, Lim K, Kim DE, Kim JS. Genome-wide specificity of dCpf1 cytidine base editors. Nature Communications. 11: 4072. PMID 32792663 DOI: 10.1038/S41467-020-17889-9 |
0.338 |
|
2019 |
Kim D, Luk K, Wolfe SA, Kim JS. Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases. Annual Review of Biochemistry. PMID 30883196 DOI: 10.1146/Annurev-Biochem-013118-111730 |
0.362 |
|
2019 |
Kim D, Kim DE, Lee G, Cho SI, Kim JS. Genome-wide target specificity of CRISPR RNA-guided adenine base editors. Nature Biotechnology. PMID 30833658 DOI: 10.1038/S41587-019-0050-1 |
0.37 |
|
2018 |
Kim D, Kim JS. DIG-seq: a genome-wide CRISPR off-target profiling method using chromatin DNA. Genome Research. PMID 30413470 DOI: 10.1101/Gr.236620.118 |
0.33 |
|
2018 |
Lee JK, Jeong E, Lee J, Jung M, Shin E, Kim YH, Lee K, Jung I, Kim D, Kim S, Kim JS. Directed evolution of CRISPR-Cas9 to increase its specificity. Nature Communications. 9: 3048. PMID 30082838 DOI: 10.1038/S41467-018-05477-X |
0.361 |
|
2018 |
Jeon Y, Choi YH, Jang Y, Yu J, Goo J, Lee G, Jeong YK, Lee SH, Kim IS, Kim JS, Jeong C, Lee S, Bae S. Direct observation of DNA target searching and cleavage by CRISPR-Cas12a. Nature Communications. 9: 2777. PMID 30018371 DOI: 10.1038/S41467-018-05245-X |
0.311 |
|
2017 |
Kweon J, Jang AH, Kim DE, Yang JW, Yoon M, Rim Shin H, Kim JS, Kim Y. Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1. Nature Communications. 8: 1723. PMID 29167440 DOI: 10.1038/S41467-017-01650-W |
0.317 |
|
2017 |
Kim S, Bae T, Hwang J, Kim JS. Rescue of high-specificity Cas9 variants using sgRNAs with matched 5' nucleotides. Genome Biology. 18: 218. PMID 29141659 DOI: 10.1186/S13059-017-1355-3 |
0.353 |
|
2017 |
Fogarty NME, McCarthy A, Snijders KE, Powell BE, Kubikova N, Blakeley P, Lea R, Elder K, Wamaitha SE, Kim D, Maciulyte V, Kleinjung J, Kim JS, Wells D, Vallier L, et al. Genome editing reveals a role for OCT4 in human embryogenesis. Nature. PMID 28953884 DOI: 10.1038/Nature24033 |
0.326 |
|
2017 |
Kim HS, Lee K, Bae S, Park J, Lee CK, Kim M, Kim E, Kim M, Kim S, Kim C, Kim JS. CRISPR/Cas9-mediated Gene-knockout Screens and Target Identification via Whole Genome Sequencing Uncover Host Genes Required for Picornavirus Infection. The Journal of Biological Chemistry. PMID 28446605 DOI: 10.1074/Jbc.M117.782425 |
0.339 |
|
2017 |
Kim SJ, Habib O, Kim JS, Han HW, Koo SK, Kim JH. A homozygous Keap1-knockout human embryonic stem cell line generated using CRISPR/Cas9 mediates gene targeting. Stem Cell Research. 19: 52-54. PMID 28413007 DOI: 10.1016/J.Scr.2016.12.028 |
0.313 |
|
2017 |
Kim D, Lim K, Kim ST, Yoon SH, Kim K, Ryu SM, Kim JS. Genome-wide target specificities of CRISPR RNA-guided programmable deaminases. Nature Biotechnology. PMID 28398345 DOI: 10.1038/Nbt.3852 |
0.343 |
|
2017 |
Kim H, Kim ST, Ryu J, Kang BC, Kim JS, Kim SG. CRISPR/Cpf1-mediated DNA-free plant genome editing. Nature Communications. 8: 14406. PMID 28205546 DOI: 10.1038/Ncomms14406 |
0.347 |
|
2016 |
Malnoy M, Viola R, Jung MH, Koo OJ, Kim S, Kim JS, Velasco R, Nagamangala Kanchiswamy C. DNA-Free Genetically Edited Grapevine and Apple Protoplast Using CRISPR/Cas9 Ribonucleoproteins. Frontiers in Plant Science. 7: 1904. PMID 28066464 DOI: 10.3389/Fpls.2016.01904 |
0.333 |
|
2016 |
Thomas SP, Kim E, Kim JS, Raines RT. Knockout of the Ribonuclease Inhibitor Gene Leaves Human Cells Vulnerable to Secretory Ribonucleases. Biochemistry. PMID 27806571 DOI: 10.1021/Acs.Biochem.6B01003 |
0.504 |
|
2016 |
Lim Y, Bak SY, Sung K, Jeong E, Lee SH, Kim JS, Bae S, Kim SK. Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease. Nature Communications. 7: 13350. PMID 27804953 DOI: 10.1038/Ncomms13350 |
0.316 |
|
2016 |
Kim JS. Genome editing comes of age. Nature Protocols. 11: 1573-1578. PMID 27490630 DOI: 10.1038/Nprot.2016.104 |
0.324 |
|
2016 |
Shin SE, Lim JM, Koh HG, Kim EK, Kang NK, Jeon S, Kwon S, Shin WS, Lee B, Hwangbo K, Kim J, Ye SH, Yun JY, Seo H, Oh HM, ... ... Kim JS, et al. CRISPR/Cas9-induced knockout and knock-in mutations in Chlamydomonas reinhardtii. Scientific Reports. 6: 27810. PMID 27291619 DOI: 10.1038/Srep27810 |
0.321 |
|
2016 |
Kim D, Kim J, Hur JK, Been KW, Yoon SH, Kim JS. Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells. Nature Biotechnology. PMID 27272384 DOI: 10.1038/Nbt.3609 |
0.354 |
|
2016 |
Kim H, Kim ST, Ryu J, Choi MK, Kweon J, Kang BC, Ahn HM, Bae S, Kim JS, Kim SG. A simple, flexible and high-throughput cloning system for plant genome editing via CRISPR-Cas system. Journal of Integrative Plant Biology. PMID 26946469 DOI: 10.1111/Jipb.12474 |
0.347 |
|
2016 |
Kim D, Kim S, Kim S, Park J, Kim JS. Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq. Genome Research. PMID 26786045 DOI: 10.1101/Gr.199588.115 |
0.338 |
|
2015 |
Witte H, Moreno E, Rödelsperger C, Kim J, Kim JS, Streit A, Sommer RJ. Gene inactivation using the CRISPR/Cas9 system in the nematode Pristionchus pacificus. Development Genes and Evolution. 225: 55-62. PMID 25548084 DOI: 10.1007/S00427-014-0486-8 |
0.317 |
|
2014 |
Song M, Kim YH, Kim JS, Kim H. Genome engineering in human cells. Methods in Enzymology. 546: 93-118. PMID 25398337 DOI: 10.1016/B978-0-12-801185-0.00005-2 |
0.348 |
|
2014 |
Park TS, Lee HJ, Kim KH, Kim JS, Han JY. Targeted gene knockout in chickens mediated by TALENs. Proceedings of the National Academy of Sciences of the United States of America. 111: 12716-21. PMID 25139993 DOI: 10.1073/Pnas.1410555111 |
0.337 |
|
2014 |
Koo OJ, Park SJ, Lee C, Kang JT, Kim S, Moon JH, Choi JY, Kim H, Jang G, Kim JS, Kim S, Lee BC. Production of Mutated Porcine Embryos Using Zinc Finger Nucleases and a Reporter-based Cell Enrichment System. Asian-Australasian Journal of Animal Sciences. 27: 324-9. PMID 25049958 DOI: 10.5713/Ajas.2013.13481 |
0.314 |
|
2014 |
Lee JS, Kwak SJ, Kim J, Kim AK, Noh HM, Kim JS, Yu K. RNA-guided genome editing in Drosophila with the purified Cas9 protein. G3 (Bethesda, Md.). 4: 1291-5. PMID 24875628 DOI: 10.1534/G3.114.012179 |
0.323 |
|
2014 |
Moon J, Lee C, Kim SJ, Choi JY, Lee BC, Kim JS, Jang G. Production of CMAH Knockout Preimplantation Embryos Derived From Immortalized Porcine Cells Via TALE Nucleases. Molecular Therapy. Nucleic Acids. 3: e166. PMID 24866481 DOI: 10.1038/Mtna.2014.15 |
0.314 |
|
2014 |
Kim YH, Ramakrishna S, Kim H, Kim JS. Enrichment of cells with TALEN-induced mutations using surrogate reporters. Methods (San Diego, Calif.). 69: 108-17. PMID 24780521 DOI: 10.1016/J.Ymeth.2014.04.012 |
0.336 |
|
2014 |
Kim S, Kim D, Cho SW, Kim J, Kim JS. Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins. Genome Research. 24: 1012-9. PMID 24696461 DOI: 10.1101/Gr.171322.113 |
0.365 |
|
2014 |
Kim H, Kim JS. A guide to genome engineering with programmable nucleases. Nature Reviews. Genetics. 15: 321-34. PMID 24690881 DOI: 10.1038/Nrg3686 |
0.36 |
|
2014 |
Ramakrishna S, Cho SW, Kim S, Song M, Gopalappa R, Kim JS, Kim H. Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations. Nature Communications. 5: 3378. PMID 24569644 DOI: 10.1038/Ncomms4378 |
0.317 |
|
2014 |
Bae S, Park J, Kim JS. Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases. Bioinformatics (Oxford, England). 30: 1473-5. PMID 24463181 DOI: 10.1093/Bioinformatics/Btu048 |
0.305 |
|
2014 |
Kim JM, Kim D, Kim S, Kim JS. Genotyping with CRISPR-Cas-derived RNA-guided endonucleases. Nature Communications. 5: 3157. PMID 24445736 DOI: 10.1038/Ncomms4157 |
0.317 |
|
2014 |
Cho SW, Kim S, Kim Y, Kweon J, Kim HS, Bae S, Kim JS. Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. Genome Research. 24: 132-41. PMID 24253446 DOI: 10.1101/Gr.162339.113 |
0.355 |
|
2013 |
Kim H, Kim MS, Wee G, Lee CI, Kim H, Kim JS. Magnetic separation and antibiotics selection enable enrichment of cells with ZFN/TALEN-induced mutations. Plos One. 8: e56476. PMID 23441197 DOI: 10.1371/Journal.Pone.0056476 |
0.317 |
|
2013 |
Cho SW, Kim S, Kim JM, Kim JS. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nature Biotechnology. 31: 230-2. PMID 23360966 DOI: 10.1038/Nbt.2507 |
0.329 |
|
2012 |
Kim E, Kim S, Kim DH, Choi BS, Choi IY, Kim JS. Precision genome engineering with programmable DNA-nicking enzymes. Genome Research. 22: 1327-33. PMID 22522391 DOI: 10.1101/Gr.138792.112 |
0.326 |
|
2012 |
Lee HJ, Kweon J, Kim E, Kim S, Kim JS. Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases. Genome Research. 22: 539-48. PMID 22183967 DOI: 10.1101/Gr.129635.111 |
0.321 |
|
2011 |
Kim H, Um E, Cho SR, Jung C, Kim H, Kim JS. Surrogate reporters for enrichment of cells with nuclease-induced mutations. Nature Methods. 8: 941-3. PMID 21983922 DOI: 10.1038/Nmeth.1733 |
0.322 |
|
2010 |
Lee HJ, Kim E, Kim J. Targeted chromosomal deletions in human cells using zinc finger nucleases Genome Research. 20: 81-89. PMID 19952142 DOI: 10.1101/Gr.099747.109 |
0.336 |
|
2009 |
Kim HJ, Lee HJ, Kim H, Cho SW, Kim JS. Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly. Genome Research. 19: 1279-88. PMID 19470664 DOI: 10.1101/Gr.089417.108 |
0.349 |
|
2008 |
Yun CO, Shin HC, Kim TD, Yoon WH, Kang YA, Kwon HS, Kim SK, Kim JS. Transduction of artificial transcriptional regulatory proteins into human cells. Nucleic Acids Research. 36: e103. PMID 18644841 DOI: 10.1093/Nar/Gkn398 |
0.355 |
|
2005 |
Park K, Jang Y, Lee H, Kim J. Phenotypic Alteration and Target Gene Identification Using Combinatorial Libraries of Zinc Finger Proteins in Prokaryotic Cells Journal of Bacteriology. 187: 5496-5499. PMID 16030245 DOI: 10.1128/Jb.187.15.5496-5499.2005 |
0.354 |
|
2005 |
Park KS, Seol W, Yang HY, Lee SI, Kim SK, Kwon RJ, Kim EJ, Roh YH, Seong BL, Kim JS. Identification and use of zinc finger transcription factors that increase production of recombinant proteins in yeast and mammalian cells. Biotechnology Progress. 21: 664-70. PMID 15932240 DOI: 10.1021/Bp049658X |
0.355 |
|
2004 |
Lee D, Kim YH, Kim J, Seol W. Induction and characterization of taxol-resistance phenotypes with a transiently expressed artificial transcriptional activator library. Nucleic Acids Research. 32. PMID 15304545 DOI: 10.1093/Nar/Gnh114 |
0.322 |
|
2003 |
Lee DK, Park JW, Kim YJ, Kim J, Lee Y, Kim J, Kim JS. Toward a functional annotation of the human genome using artificial transcription factors. Genome Research. 13: 2708-16. PMID 14656973 DOI: 10.1101/Gr.1397903 |
0.308 |
|
2003 |
Park K, Lee D, Lee H, Lee Y, Jang Y, Kim YH, Yang H, Lee S, Seol W, Kim J. Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors. Nature Biotechnology. 21: 1208-1214. PMID 12960965 DOI: 10.1038/Nbt868 |
0.347 |
|
2003 |
Bae KH, Kwon YD, Shin HC, Hwang MS, Ryu EH, Park KS, Yang HY, Lee DK, Lee Y, Park J, Kwon HS, Kim HW, Yeh BI, Lee HW, Sohn SH, ... ... Kim JS, et al. Human zinc fingers as building blocks in the construction of artificial transcription factors. Nature Biotechnology. 21: 275-80. PMID 12592413 DOI: 10.1038/Nbt796 |
0.348 |
|
2003 |
Lee D, Seol W, Kim J. Custom DNA-Binding Proteins and Artificial Transcription Factors Current Topics in Medicinal Chemistry. 3: 645-657. PMID 12570857 DOI: 10.2174/1568026033452384 |
0.315 |
|
2000 |
Kang JS, Kim JS. Zinc finger proteins as designer transcription factors Journal of Biological Chemistry. 275: 8742-8748. PMID 10722717 DOI: 10.1074/Jbc.275.12.8742 |
0.364 |
|
1998 |
Kim JS, Pabo CO. Getting a handhold on DNA: design of poly-zinc finger proteins with femtomolar dissociation constants. Proceedings of the National Academy of Sciences of the United States of America. 95: 2812-7. PMID 9501172 DOI: 10.1073/Pnas.95.6.2812 |
0.616 |
|
1997 |
Matoušek J, Kim JS, Souček J, Rìha J, Ribó M, Leland PA, Raines RT. Ribonucleases endowed with specific toxicity for spermatogenic layers. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 118: 881-888. PMID 21399757 DOI: 10.1016/S0305-0491(97)00278-2 |
0.724 |
|
1997 |
Kim JS, Pabo CO. Transcriptional repression by zinc finger peptides. Exploring the potential for applications in gene therapy. The Journal of Biological Chemistry. 272: 29795-800. PMID 9368051 DOI: 10.1074/Jbc.272.47.29795 |
0.61 |
|
1997 |
Kim JS, Kim J, Cepek KL, Sharp PA, Pabo CO. Design of TATA box-binding protein/zinc finger fusions for targeted regulation of gene expression. Proceedings of the National Academy of Sciences of the United States of America. 94: 3616-20. PMID 9108026 DOI: 10.1073/Pnas.94.8.3616 |
0.631 |
|
1995 |
Kim JS, Soucek J, Matousek J, Raines RT. Mechanism of ribonuclease cytotoxicity. The Journal of Biological Chemistry. 270: 31097-102. PMID 8537370 DOI: 10.1074/Jbc.270.52.31097 |
0.478 |
|
1995 |
Kim JS, Raines RT. Dibromobimane as a fluorescent crosslinking reagent. Analytical Biochemistry. 225: 174-6. PMID 7778775 DOI: 10.1006/Abio.1995.1131 |
0.403 |
|
1995 |
Kim JS, Soucek J, Matousek J, Raines RT. Catalytic activity of bovine seminal ribonuclease is essential for its immunosuppressive and other biological activities. The Biochemical Journal. 308: 547-50. PMID 7772040 DOI: 10.1042/Bj3080547 |
0.478 |
|
1995 |
Kim JS, Soucek J, Matousek J, Raines RT. Structural basis for the biological activities of bovine seminal ribonuclease. The Journal of Biological Chemistry. 270: 10525-30. PMID 7737987 DOI: 10.1074/Jbc.270.18.10525 |
0.43 |
|
1994 |
Kim JS, Raines RT. A misfolded but active dimer of bovine seminal ribonuclease. European Journal of Biochemistry / Febs. 224: 109-14. PMID 8076630 DOI: 10.1111/J.1432-1033.1994.Tb20001.X |
0.464 |
|
1994 |
Kim JS, Raines RT. Peptide tags for a dual affinity fusion system. Analytical Biochemistry. 219: 165-6. PMID 8059949 DOI: 10.1006/Abio.1994.1251 |
0.49 |
|
1993 |
Kim JS, Raines RT. Ribonuclease S-peptide as a carrier in fusion proteins. Protein Science : a Publication of the Protein Society. 2: 348-56. PMID 8453373 DOI: 10.1002/Pro.5560020307 |
0.479 |
|
1993 |
Kim JS, Raines RT. Bovine seminal ribonuclease produced from a synthetic gene. The Journal of Biological Chemistry. 268: 17392-6. PMID 7688724 |
0.44 |
|
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