| Year |
Citation |
Score |
| 2024 |
Sun N, Cai Q, Zhang Y, Zhang RR, Jiang J, Yang H, Qin CF, Cheng G. The aldehyde dehydrogenase ALDH1B1 exerts antiviral effects through the aggregation of the adaptor MAVS. Science Signaling. 17: eadf8016. PMID 38194477 DOI: 10.1126/scisignal.adf8016 |
0.329 |
|
| 2022 |
Zu S, Li C, Li L, Deng YQ, Chen X, Luo D, Ye Q, Huang YJ, Li XF, Zhang RR, Sun N, Zhang X, Aliyari SR, Nielsen-Saines K, Jung JU, ... ... Cheng G, et al. TRIM22 suppresses Zika virus replication by targeting NS1 and NS3 for proteasomal degradation. Cell & Bioscience. 12: 139. PMID 36042495 DOI: 10.1186/s13578-022-00872-w |
0.356 |
|
| 2022 |
Aliyari SR, Quanquin N, Pernet O, Zhang S, Wang L, Cheng G. The Evolutionary Dance between Innate Host Antiviral Pathways and SARS-CoV-2. Pathogens (Basel, Switzerland). 11. PMID 35631059 DOI: 10.3390/pathogens11050538 |
0.313 |
|
| 2022 |
Aliyari SR, Ghaffari AA, Pernet O, Parvatiyar K, Wang Y, Gerami H, Tong AJ, Vergnes L, Takallou A, Zhang A, Wei X, Chilin LD, Wu Y, Semenkovich CF, Reue K, ... ... Cheng G, et al. Suppressing fatty acid synthase by type I interferon and chemical inhibitors as a broad spectrum anti-viral strategy against SARS-CoV-2. Acta Pharmaceutica Sinica. B. PMID 35251918 DOI: 10.1016/j.apsb.2022.02.019 |
0.599 |
|
| 2022 |
Zhao J, Chen J, Wang C, Liu Y, Li M, Li Y, Li R, Han Z, Wang J, Chen L, Shu Y, Cheng G, Sun C. Kynurenine-3-monooxygenase (KMO) broadly inhibits viral infections via triggering NMDAR/Ca2+ influx and CaMKII/ IRF3-mediated IFN-β production. Plos Pathogens. 18: e1010366. PMID 35235615 DOI: 10.1371/journal.ppat.1010366 |
0.31 |
|
| 2022 |
Yang L, Chen S, Zhao Q, Pan C, Peng L, Han Y, Li L, Ruan J, Xia J, Yang H, Xu F, Cheng G. Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription. Cell Reports. 38: 110302. PMID 35081346 DOI: 10.1016/j.celrep.2022.110302 |
0.348 |
|
| 2020 |
Quanquin NM, Barres LG, Aliyari SR, Day NT, Gerami H, Fisher SJ, Kakuru A, Kamya MR, Havlir DV, Feeney M, Dorsey G, Cheng G, Gaw SL. Gravidity-dependent associations between interferon response and birth weight in placental malaria. Malaria Journal. 19: 280. PMID 32758231 DOI: 10.1186/S12936-020-03351-0 |
0.33 |
|
| 2019 |
Tan G, Yi Z, Song H, Xu F, Li F, Aliyari R, Zhang H, Du P, Ding Y, Niu J, Wang X, Su L, Qin FX, Cheng G. Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation. Cell Reports. 29: 3551-3563.e3. PMID 31825835 DOI: 10.1016/J.Celrep.2019.11.041 |
0.385 |
|
| 2019 |
Du X, Zuo X, Meng F, Wu F, Zhao X, Li C, Cheng G, Qin FX. Combinatorial screening of a panel of FDA-approved drugs identifies several candidates with anti-Ebola activities. Biochemical and Biophysical Research Communications. PMID 31806372 DOI: 10.1016/J.Bbrc.2019.11.065 |
0.306 |
|
| 2019 |
Xu F, Song H, An B, Xiao Q, Cheng G, Tan G. NF-κB-Dependent IFIT3 Induction by HBx Promotes Hepatitis B Virus Replication. Frontiers in Microbiology. 10: 2382. PMID 31681236 DOI: 10.3389/Fmicb.2019.02382 |
0.397 |
|
| 2019 |
Sun J, Wang J, Yuan X, Wu X, Sui T, Wu A, Cheng G, Jiang T. Regulation of Early Host Immune Responses Shapes the Pathogenicity of Avian Influenza A Virus. Frontiers in Microbiology. 10: 2007. PMID 31572308 DOI: 10.3389/Fmicb.2019.02007 |
0.451 |
|
| 2019 |
Ding X, Krutzik PO, Ghaffari AA, Zhaozhi Y, Miranda D, Cheng G, Ho CM, Nolan GP, Sanchez DJ. Cellular Signaling Analysis shows antiviral, ribavirin-mediated ribosomal signaling modulation. Antiviral Research. 104598. PMID 31513822 DOI: 10.1016/J.Antiviral.2019.104598 |
0.642 |
|
| 2019 |
Chapon M, Parvatiyar K, Aliyari SR, Zhao JS, Cheng G. Comprehensive mutagenesis of HSV-1 genome identifies UL42 as an inhibitor of type I interferon induction. Journal of Virology. PMID 31511375 DOI: 10.1128/Jvi.01446-19 |
0.383 |
|
| 2019 |
Dang AT, Teles RM, Liu PT, Choi A, Legaspi A, Sarno EN, Ochoa MT, Parvatiyar K, Cheng G, Gilliet M, Bloom BR, Modlin RL. Autophagy links antimicrobial activity with antigen presentation in Langerhans cells. Jci Insight. 4. PMID 30996142 DOI: 10.1172/Jci.Insight.126955 |
0.374 |
|
| 2019 |
Dang AT, Teles RM, Weiss DI, Parvatiyar K, Sarno EN, Ochoa MT, Cheng G, Gilliet M, Bloom BR, Modlin RL. IL-26 contributes to host defense against intracellular bacteria. The Journal of Clinical Investigation. 130. PMID 30939123 DOI: 10.1172/Jci99550 |
0.322 |
|
| 2018 |
Tan G, Xu F, Song H, Yuan Y, Xiao Q, Ma F, Qin FX, Cheng G. Identification of as a Type I IFN-Stimulated Gene Controlling Hepatitis B Virus Replication by Targeting HBx. Frontiers in Immunology. 9: 1872. PMID 30150992 DOI: 10.3389/fimmu.2018.01872 |
0.316 |
|
| 2018 |
Tan G, Song H, Xu F, Cheng G. When Hepatitis B Virus Meets Interferons. Frontiers in Microbiology. 9: 1611. PMID 30072974 DOI: 10.3389/Fmicb.2018.01611 |
0.363 |
|
| 2018 |
Parvatiyar K, Pindado J, Dev A, Aliyari SR, Zaver SA, Gerami H, Chapon M, Ghaffari AA, Dhingra A, Cheng G. A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling. Nature Communications. 9: 2770. PMID 30018345 DOI: 10.1038/S41467-018-05168-7 |
0.654 |
|
| 2018 |
Li L, Zhao H, Liu P, Li C, Quanquin N, Ji X, Sun N, Du P, Qin CF, Lu N, Cheng G. suppresses Zika virus infection through PARP-dependent degradation of NS1 and NS3 viral proteins. Science Signaling. 11. PMID 29921658 DOI: 10.1126/Scisignal.Aas9332 |
0.405 |
|
| 2018 |
Xu F, Song H, Xiao Q, Li N, Zhang H, Cheng G, Tan G. Type III interferon-induced CBFβ inhibits HBV replication by hijacking HBx. Cellular & Molecular Immunology. PMID 29523836 DOI: 10.1038/S41423-018-0006-2 |
0.394 |
|
| 2017 |
Li C, Zhu X, Ji X, Quanquin N, Deng YQ, Tian M, Aliyari R, Zuo X, Yuan L, Afridi SK, Li XF, Jung JU, Nielsen-Saines K, Qin FX, Qin CF, ... ... Cheng G, et al. Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice. Ebiomedicine. PMID 29033372 DOI: 10.1016/J.Ebiom.2017.09.034 |
0.322 |
|
| 2017 |
Li C, Deng YQ, Wang S, Ma F, Aliyari R, Huang XY, Zhang NN, Watanabe M, Dong HL, Liu P, Li XF, Ye Q, Tian M, Hong S, Fan J, ... ... Cheng G, et al. 25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model. Immunity. PMID 28314593 DOI: 10.1016/J.Immuni.2017.02.012 |
0.37 |
|
| 2017 |
Wang L, Liu SY, Chen HW, Xu J, Chapon M, Zhang T, Zhou F, Wang YE, Quanquin N, Wang G, Tian X, He Z, Liu L, Yu W, Sanchez DJ, ... ... Cheng G, et al. Generation of a Live Attenuated Influenza Vaccine that Elicits Broad Protection in Mice and Ferrets. Cell Host & Microbe. 21: 334-343. PMID 28279345 DOI: 10.1016/J.Chom.2017.02.007 |
0.669 |
|
| 2017 |
Tan G, Xiao Q, Song H, Ma F, Xu F, Peng D, Li N, Wang X, Niu J, Gao P, Qin FX, Cheng G. Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication. Cellular & Molecular Immunology. PMID 28194021 DOI: 10.1038/Cmi.2016.67 |
0.403 |
|
| 2016 |
Li C, Wang Z, Cao Y, Wang L, Ji J, Chen Z, Deng T, Jiang T, Cheng G, Qin FX. Screening for novel small molecule inhibitors targeting the assembling of influenza virus polymerase complex by a BiLC-based reporter system. Journal of Virology. PMID 28031371 DOI: 10.1128/Jvi.02282-16 |
0.3 |
|
| 2016 |
Li J, Rodriguez JP, Niu F, Pu M, Wang J, Hung LW, Shao Q, Zhu Y, Ding W, Liu Y, Da Y, Yao Z, Yang J, Zhao Y, Wei GH, ... Cheng G, et al. Structural basis for DNA recognition by STAT6. Proceedings of the National Academy of Sciences of the United States of America. PMID 27803324 DOI: 10.1073/Pnas.1611228113 |
0.327 |
|
| 2016 |
Wang S, Chen Y, Li C, Wu Y, Guo L, Peng C, Huang Y, Cheng G, Qin FX. TRIM14 inhibits hepatitis C virus infection by SPRY domain-dependent targeted degradation of the viral NS5A protein. Scientific Reports. 6: 32336. PMID 27578425 DOI: 10.1038/Srep32336 |
0.378 |
|
| 2016 |
Boxx GM, Cheng G. The Roles of Type I Interferon in Bacterial Infection. Cell Host & Microbe. 19: 760-769. PMID 27281568 DOI: 10.1016/J.Chom.2016.05.016 |
0.45 |
|
| 2016 |
Deriu E, Boxx GM, He X, Pan C, Benavidez SD, Cen L, Rozengurt N, Shi W, Cheng G. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. Plos Pathogens. 12: e1005572. PMID 27149619 DOI: 10.1371/Journal.Ppat.1005572 |
0.367 |
|
| 2016 |
Wang Z, Ji J, Peng D, Ma F, Cheng G, Qin FX. Complex Regulation Pattern of IRF3 Activation Revealed by a Novel Dimerization Reporter System. Journal of Immunology (Baltimore, Md. : 1950). PMID 27045107 DOI: 10.4049/Jimmunol.1502458 |
0.486 |
|
| 2016 |
Bednarski JJ, Pandey R, Schulte E, White LS, Chen BR, Sandoval GJ, Kohyama M, Haldar M, Nickless A, Trott A, Cheng G, Murphy KM, Bassing CH, Payton JE, Sleckman BP. RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals. The Journal of Experimental Medicine. PMID 26834154 DOI: 10.1084/Jem.20151048 |
0.368 |
|
| 2015 |
Wang L, Wu A, Wang YE, Quanquin N, Li C, Wang J, Chen HW, Liu S, Liu P, Zhang H, Qin FX, Jiang T, Cheng G. Functional Genomics Reveals Linkers Critical for Influenza Polymerase. Journal of Virology. PMID 26719244 DOI: 10.1128/Jvi.02400-15 |
0.482 |
|
| 2015 |
Chen Y, He L, Peng Y, Shi X, Chen J, Zhong J, Chen X, Cheng G, Deng H. The hepatitis C virus protein NS3 suppresses TNF-α-stimulated activation of NF-κB by targeting LUBAC. Science Signaling. 8: ra118. PMID 26577923 DOI: 10.1126/Scisignal.Aab2159 |
0.422 |
|
| 2015 |
Sanchez DJ, Miranda D, Marsden MD, Dizon TM, Bontemps JR, Davila SJ, Del Mundo LE, Ha T, Senaati A, Zack JA, Cheng G. Disruption of Type I Interferon Induction by HIV Infection of T Cells. Plos One. 10: e0137951. PMID 26375588 DOI: 10.1371/Journal.Pone.0137951 |
0.656 |
|
| 2015 |
Teles RM, Kelly-Scumpia KM, Sarno EN, Rea TH, Ochoa MT, Cheng G, Modlin RL. IL-27 Suppresses Antimicrobial Activity in Human Leprosy. The Journal of Investigative Dermatology. 135: 2410-7. PMID 26030183 DOI: 10.1038/Jid.2015.195 |
0.33 |
|
| 2015 |
Reichardt AD, Pindado J, Zaver SA, Cheng G. TRAF protein function in noncanonical NF-κB signaling. Methods in Molecular Biology (Clifton, N.J.). 1280: 247-68. PMID 25736753 DOI: 10.1007/978-1-4939-2422-6_14 |
0.373 |
|
| 2015 |
Ma F, Li B, Liu SY, Iyer SS, Yu Y, Wu A, Cheng G. Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS. Journal of Immunology (Baltimore, Md. : 1950). 194: 1545-54. PMID 25609843 DOI: 10.4049/Jimmunol.1402066 |
0.63 |
|
| 2015 |
Ma F, Li B, Yu Y, Iyer SS, Sun M, Cheng G. Positive feedback regulation of type I interferon by the interferon-stimulated gene STING. Embo Reports. 16: 202-12. PMID 25572843 DOI: 10.15252/Embr.201439366 |
0.432 |
|
| 2015 |
He X, McLean JS, Edlund A, Yooseph S, Hall AP, Liu SY, Dorrestein PC, Esquenazi E, Hunter RC, Cheng G, Nelson KE, Lux R, Shi W. Cultivation of a human-associated TM7 phylotype reveals a reduced genome and epibiotic parasitic lifestyle. Proceedings of the National Academy of Sciences of the United States of America. 112: 244-9. PMID 25535390 DOI: 10.1073/Pnas.1419038112 |
0.565 |
|
| 2014 |
Chen Y, Wang S, Yi Z, Tian H, Aliyari R, Li Y, Chen G, Liu P, Zhong J, Chen X, Du P, Su L, Qin FX, Deng H, Cheng G. Interferon-inducible cholesterol-25-hydroxylase inhibits hepatitis C virus replication via distinct mechanisms. Scientific Reports. 4: 7242. PMID 25467815 DOI: 10.1038/Srep07242 |
0.316 |
|
| 2014 |
Ma F, Liu SY, Razani B, Arora N, Li B, Kagechika H, Tontonoz P, Núñez V, Ricote M, Cheng G. Retinoid X receptor α attenuates host antiviral response by suppressing type I interferon. Nature Communications. 5: 5494. PMID 25417649 DOI: 10.1038/Ncomms6494 |
0.79 |
|
| 2013 |
Gillespie EJ, Ho CL, Balaji K, Clemens DL, Deng G, Wang YE, Elsaesser HJ, Tamilselvam B, Gargi A, Dixon SD, France B, Chamberlain BT, Blanke SR, Cheng G, de la Torre JC, et al. Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses. Proceedings of the National Academy of Sciences of the United States of America. 110: E4904-12. PMID 24191014 DOI: 10.1073/Pnas.1302334110 |
0.324 |
|
| 2013 |
Wang Y, Shaked I, Stanford SM, Zhou W, Curtsinger JM, Mikulski Z, Shaheen ZR, Cheng G, Sawatzke K, Campbell AM, Auger JL, Bilgic H, Shoyama FM, Schmeling DO, Balfour HH, et al. The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity. Immunity. 39: 111-22. PMID 23871208 DOI: 10.1016/J.Immuni.2013.06.013 |
0.478 |
|
| 2013 |
Wilson EB, Yamada DH, Elsaesser H, Herskovitz J, Deng J, Cheng G, Aronow BJ, Karp CL, Brooks DG. Blockade of chronic type I interferon signaling to control persistent LCMV infection. Science (New York, N.Y.). 340: 202-7. PMID 23580528 DOI: 10.1126/Science.1235208 |
0.438 |
|
| 2013 |
Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, ... ... Cheng G, et al. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science (New York, N.Y.). 339: 1448-53. PMID 23449998 DOI: 10.1126/Science.1233665 |
0.42 |
|
| 2013 |
Kamo N, Ke B, Ghaffari AA, Shen XD, Busuttil RW, Cheng G, Kupiec-Weglinski JW. ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury. Hepatology (Baltimore, Md.). 58: 351-62. PMID 23408710 DOI: 10.1002/Hep.26320 |
0.368 |
|
| 2013 |
Liu SY, Aliyari R, Chikere K, Li G, Marsden MD, Smith JK, Pernet O, Guo H, Nusbaum R, Zack JA, Freiberg AN, Su L, Lee B, Cheng G. Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol. Immunity. 38: 92-105. PMID 23273844 DOI: 10.1016/J.Immuni.2012.11.005 |
0.598 |
|
| 2012 |
Cho JS, Guo Y, Ramos RI, Hebroni F, Plaisier SB, Xuan C, Granick JL, Matsushima H, Takashima A, Iwakura Y, Cheung AL, Cheng G, Lee DJ, Simon SI, Miller LS. Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice. Plos Pathogens. 8: e1003047. PMID 23209417 DOI: 10.1371/Journal.Ppat.1003047 |
0.336 |
|
| 2012 |
Zhang P, Reichardt A, Liang H, Aliyari R, Cheng D, Wang Y, Xu F, Cheng G, Liu Y. Single amino acid substitutions confer the antiviral activity of the TRAF3 adaptor protein onto TRAF5. Science Signaling. 5: ra81. PMID 23150880 DOI: 10.1126/Scisignal.2003152 |
0.466 |
|
| 2012 |
Parvatiyar K, Zhang Z, Teles RM, Ouyang S, Jiang Y, Iyer SS, Zaver SA, Schenk M, Zeng S, Zhong W, Liu ZJ, Modlin RL, Liu YJ, Cheng G. The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nature Immunology. 13: 1155-61. PMID 23142775 DOI: 10.1038/Ni.2460 |
0.374 |
|
| 2012 |
Tian X, Xu F, Lung WY, Meyerson C, Ghaffari AA, Cheng G, Deng JC. Poly I:C enhances susceptibility to secondary pulmonary infections by gram-positive bacteria. Plos One. 7: e41879. PMID 22962579 DOI: 10.1371/Journal.Pone.0041879 |
0.416 |
|
| 2012 |
Liu SY, Guo JY, Zhang L, Liu ZS, Zheng ZH, Cheng GY, Gao GM, Zhang X, Liu GZ, Zeng XF. [Incidence of metabolic syndrome in systemic lupus erythematosus and its influence by glucocorticoids]. Zhonghua Nei Ke Za Zhi. 51: 441-4. PMID 22943753 |
0.428 |
|
| 2012 |
Ding X, Sanchez DJ, Shahangian A, Al-Shyoukh I, Cheng G, Ho CM. Cascade search for HSV-1 combinatorial drugs with high antiviral efficacy and low toxicity. International Journal of Nanomedicine. 7: 2281-92. PMID 22654513 DOI: 10.2147/Ijn.S27540 |
0.767 |
|
| 2012 |
Li J, Li J, Miyahira A, Sun J, Liu Y, Cheng G, Liang H. Crystal structure of the ubiquitin-like domain of human TBK1. Protein & Cell. 3: 383-91. PMID 22610919 DOI: 10.1007/s13238-012-2929-1 |
0.707 |
|
| 2012 |
Ouyang S, Song X, Wang Y, Ru H, Shaw N, Jiang Y, Niu F, Zhu Y, Qiu W, Parvatiyar K, Li Y, Zhang R, Cheng G, Liu ZJ. Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding. Immunity. 36: 1073-86. PMID 22579474 DOI: 10.1016/J.Immuni.2012.03.019 |
0.324 |
|
| 2012 |
Schenk M, Krutzik SR, Sieling PA, Lee DJ, Teles RM, Ochoa MT, Komisopoulou E, Sarno EN, Rea TH, Graeber TG, Kim S, Cheng G, Modlin RL. NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nature Medicine. 18: 555-63. PMID 22447076 DOI: 10.1038/Nm.2650 |
0.41 |
|
| 2012 |
Iyer SS, Cheng G. Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease. Critical Reviews in Immunology. 32: 23-63. PMID 22428854 DOI: 10.1615/Critrevimmunol.V32.I1.30 |
0.384 |
|
| 2012 |
Liu SY, Sanchez DJ, Aliyari R, Lu S, Cheng G. Systematic identification of type I and type II interferon-induced antiviral factors. Proceedings of the National Academy of Sciences of the United States of America. 109: 4239-44. PMID 22371602 DOI: 10.1073/Pnas.1114981109 |
0.735 |
|
| 2011 |
Zhang L, Yuan S, Cheng G, Guo B. Type I IFN promotes IL-10 production from T cells to suppress Th17 cells and Th17-associated autoimmune inflammation. Plos One. 6: e28432. PMID 22163016 DOI: 10.1371/Journal.Pone.0028432 |
0.403 |
|
| 2011 |
Razani B, Reichardt AD, Cheng G. Non-canonical NF-κB signaling activation and regulation: principles and perspectives. Immunological Reviews. 244: 44-54. PMID 22017430 DOI: 10.1111/J.1600-065X.2011.01059.X |
0.725 |
|
| 2011 |
Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT, Realegeno S, Lee HM, Krutzik SR, Schenk M, Sieling PA, Teles R, Montoya D, Iyer SS, Bruns H, Lewinsohn DM, ... ... Cheng G, et al. Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Science Translational Medicine. 3: 104ra102. PMID 21998409 DOI: 10.1126/Scitranslmed.3003045 |
0.352 |
|
| 2011 |
Liu Y, Tian X, Leitner WW, Aldridge ME, Zheng J, Yu Z, Restifo NP, Weiss R, Scheiblhofer S, Xie C, Sun R, Cheng G, Zeng G. Polymeric structure and host toll-like receptor 4 dictate immunogenicity of NY-ESO-1 antigen in vivo Journal of Biological Chemistry. 286: 37077-37084. PMID 21900253 DOI: 10.1074/Jbc.M111.280123 |
0.408 |
|
| 2011 |
Koon HW, Shih DQ, Chen J, Bakirtzi K, Hing TC, Law I, Ho S, Ichikawa R, Zhao D, Xu H, Gallo R, Dempsey P, Cheng G, Targan SR, Pothoulakis C. Cathelicidin signaling via the Toll-like receptor protects against colitis in mice. Gastroenterology. 141: 1852-63.e1-3. PMID 21762664 DOI: 10.1053/J.Gastro.2011.06.079 |
0.366 |
|
| 2011 |
Zhang Z, Kim T, Bao M, Facchinetti V, Jung SY, Ghaffari AA, Qin J, Cheng G, Liu YJ. DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells. Immunity. 34: 866-78. PMID 21703541 DOI: 10.1016/J.Immuni.2011.03.027 |
0.38 |
|
| 2011 |
Pietras EM, Miller LS, Johnson CT, O'Connell RM, Dempsey PW, Cheng G. A MyD88-dependent IFNγR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge. Cell Research. 21: 1068-79. PMID 21467996 DOI: 10.1038/Cr.2011.59 |
0.755 |
|
| 2011 |
Ghaffari AA, Chow EK, Iyer SS, Deng JC, Cheng G. Polyinosinic-polycytidylic acid suppresses acetaminophen-induced hepatotoxicity independent of type I interferons and toll-like receptor 3. Hepatology (Baltimore, Md.). 53: 2042-52. PMID 21433044 DOI: 10.1002/Hep.24316 |
0.54 |
|
| 2011 |
Wang G, Chen G, Zheng D, Cheng G, Tang H. PLP2 of mouse hepatitis virus A59 (MHV-A59) targets TBK1 to negatively regulate cellular type I interferon signaling pathway. Plos One. 6: e17192. PMID 21364999 DOI: 10.1371/Journal.Pone.0017192 |
0.452 |
|
| 2011 |
Tricker E, Arvand A, Kwan R, Chen GY, Gallagher E, Cheng G. Apoptosis induced by cytoskeletal disruption requires distinct domains of MEKK1. Plos One. 6: e17310. PMID 21364884 DOI: 10.1371/Journal.Pone.0017310 |
0.78 |
|
| 2011 |
Da Q, Yang X, Xu Y, Gao G, Cheng G, Tang H. TANK-binding kinase 1 attenuates PTAP-dependent retroviral budding through targeting endosomal sorting complex required for transport-I. Journal of Immunology (Baltimore, Md. : 1950). 186: 3023-30. PMID 21270402 DOI: 10.4049/Jimmunol.1000262 |
0.397 |
|
| 2011 |
Atarashi K, Tanoue T, Shima T, Imaoka A, Kuwahara T, Momose Y, Cheng G, Yamasaki S, Saito T, Ohba Y, Taniguchi T, Takeda K, Hori S, Ivanov II, Umesaki Y, et al. Induction of colonic regulatory T cells by indigenous Clostridium species. Science (New York, N.Y.). 331: 337-41. PMID 21205640 DOI: 10.1126/Science.1198469 |
0.3 |
|
| 2011 |
Fu J, Xiong Y, Xu Y, Cheng G, Tang H. MDA5 is SUMOylated by PIAS2β in the upregulation of type I interferon signaling. Molecular Immunology. 48: 415-22. PMID 21156324 DOI: 10.1016/J.Molimm.2010.09.003 |
0.444 |
|
| 2011 |
Liu SY, Sanchez DJ, Cheng G. New developments in the induction and antiviral effectors of type I interferon. Current Opinion in Immunology. 23: 57-64. PMID 21123041 DOI: 10.1016/J.Coi.2010.11.003 |
0.757 |
|
| 2011 |
Dev A, Iyer S, Razani B, Cheng G. NF-κB and innate immunity. Current Topics in Microbiology and Immunology. 349: 115-43. PMID 20848362 DOI: 10.1007/82_2010_102 |
0.797 |
|
| 2010 |
Iyer SS, Ghaffari AA, Cheng G. Lipopolysaccharide-mediated IL-10 transcriptional regulation requires sequential induction of type I IFNs and IL-27 in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 185: 6599-607. PMID 21041726 DOI: 10.4049/Jimmunol.1002041 |
0.334 |
|
| 2010 |
Razani B, Cheng G. NF-kappaB: much learned, much to learn. Science Signaling. 3: pe29. PMID 20823402 DOI: 10.1126/Scisignal.3138Pe29 |
0.692 |
|
| 2010 |
Wang Y, Zhang P, Liu Y, Cheng G. TRAF-mediated regulation of immune and inflammatory responses. Science China. Life Sciences. 53: 159-68. PMID 20596822 DOI: 10.1007/S11427-010-0050-3 |
0.449 |
|
| 2010 |
Razani B, Zarnegar B, Ytterberg AJ, Shiba T, Dempsey PW, Ware CF, Loo JA, Cheng G. Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation. Science Signaling. 3: ra41. PMID 20501937 DOI: 10.1126/scisignal.2000778 |
0.818 |
|
| 2010 |
Zheng C, Kabaleeswaran V, Wang Y, Cheng G, Wu H. Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation. Molecular Cell. 38: 101-13. PMID 20385093 DOI: 10.1016/J.Molcel.2010.03.009 |
0.354 |
|
| 2010 |
Cho JS, Pietras EM, Garcia NC, Ramos RI, Farzam DM, Monroe HR, Magorien JE, Blauvelt A, Kolls JK, Cheung AL, Cheng G, Modlin RL, Miller LS. IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. The Journal of Clinical Investigation. 120: 1762-73. PMID 20364087 DOI: 10.1172/Jci40891 |
0.641 |
|
| 2010 |
Chin AI, Miyahira AK, Covarrubias A, Teague J, Guo B, Dempsey PW, Cheng G. Toll-like receptor 3-mediated suppression of TRAMP prostate cancer shows the critical role of type I interferons in tumor immune surveillance. Cancer Research. 70: 2595-603. PMID 20233880 DOI: 10.1158/0008-5472.Can-09-1162 |
0.808 |
|
| 2010 |
Chin A, Miyahara A, Covarrubias A, Teague J, Dempsey P, Cheng G. 548 TUMOR SURVEILLANCE BY TOLL-LIKE RECEPTOR 3 IN PROSTATE CANCER Journal of Urology. 183. DOI: 10.1016/J.Juro.2010.02.768 |
0.638 |
|
| 2009 |
Montoya D, Cruz D, Teles RM, Lee DJ, Ochoa MT, Krutzik SR, Chun R, Schenk M, Zhang X, Ferguson BG, Burdick AE, Sarno EN, Rea TH, Hewison M, Adams JS, ... Cheng G, et al. Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell Host & Microbe. 6: 343-53. PMID 19837374 DOI: 10.1016/J.Chom.2009.09.002 |
0.402 |
|
| 2009 |
Liu PT, Schenk M, Walker VP, Dempsey PW, Kanchanapoomi M, Wheelwright M, Vazirnia A, Zhang X, Steinmeyer A, Zügel U, Hollis BW, Cheng G, Modlin RL. Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses. Plos One. 4: e5810. PMID 19503839 DOI: 10.1371/Journal.Pone.0005810 |
0.402 |
|
| 2009 |
Shahangian A, Chow EK, Tian X, Kang JR, Ghaffari A, Liu SY, Belperio JA, Cheng G, Deng JC. Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice. The Journal of Clinical Investigation. 119: 1910-20. PMID 19487810 DOI: 10.1172/Jci35412 |
0.805 |
|
| 2009 |
Hwang S, Kim KS, Flano E, Wu TT, Tong LM, Park AN, Song MJ, Sanchez DJ, O'Connell RM, Cheng G, Sun R. Conserved herpesviral kinase promotes viral persistence by inhibiting the IRF-3-mediated type I interferon response. Cell Host & Microbe. 5: 166-78. PMID 19218087 DOI: 10.1016/J.Chom.2008.12.013 |
0.769 |
|
| 2009 |
Miyahira AK, Shahangian A, Hwang S, Sun R, Cheng G. TANK-binding kinase-1 plays an important role during in vitro and in vivo type I IFN responses to DNA virus infections. Journal of Immunology (Baltimore, Md. : 1950). 182: 2248-57. PMID 19201879 DOI: 10.4049/Jimmunol.0802466 |
0.817 |
|
| 2009 |
Chin AI, Miyahara A, Covarrubias A, Dempsey PW, Cheng G. SUPPRESSION OF PROSTATE CANCER GROWTH WITH ACTIVATION OF TOLL-LIKE RECEPTOR 3 Journal of Urology. 181: 186-186. DOI: 10.1016/S0022-5347(09)60536-X |
0.65 |
|
| 2008 |
Chow EK, Pierstorff E, Cheng G, Ho D. Copolymeric nanofilm platform for controlled and localized therapeutic delivery. Acs Nano. 2: 33-40. PMID 19206545 DOI: 10.1021/Nn7000917 |
0.487 |
|
| 2008 |
Cheng LS, Hwang S, Huang TH, Sheu TC, Sun R, Morrison SL, Cheng G, Shahangian A. Antibody-fused interferons as an effective approach to enhance target specificity and antiviral efficacy of type I interferons. Cell Research. 18: 1230-2. PMID 19002159 DOI: 10.1038/Cr.2008.304 |
0.748 |
|
| 2008 |
Zarnegar BJ, Wang Y, Mahoney DJ, Dempsey PW, Cheung HH, He J, Shiba T, Yang X, Yeh WC, Mak TW, Korneluk RG, Cheng G. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nature Immunology. 9: 1371-8. PMID 18997794 DOI: 10.1038/Ni.1676 |
0.791 |
|
| 2008 |
Zheng D, Chen G, Guo B, Cheng G, Tang H. PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production. Cell Research. 18: 1105-13. PMID 18957937 DOI: 10.1038/Cr.2008.294 |
0.428 |
|
| 2008 |
Pietras EM, Cheng G. A New TRADDition in intracellular antiviral signaling. Science Signaling. 1: pe36. PMID 18664658 DOI: 10.1126/Scisignal.130Pe36 |
0.716 |
|
| 2008 |
Tricker E, Cheng G. With a little help from my friends: modulation of phagocytosis through TLR activation. Cell Research. 18: 711-2. PMID 18596701 DOI: 10.1038/Cr.2008.78 |
0.794 |
|
| 2008 |
Pietras EM, Cheng G. New tricks for old NODs. Genome Biology. 9: 217. PMID 18466630 DOI: 10.1186/Gb-2008-9-4-217 |
0.673 |
|
| 2008 |
Zhai Y, Qiao B, Shen XD, Gao F, Busuttil RW, Cheng G, Platt JL, Volk HD, Kupiec-Weglinski JW. Evidence for the pivotal role of endogenous toll-like receptor 4 ligands in liver ischemia and reperfusion injury. Transplantation. 85: 1016-22. PMID 18408583 DOI: 10.1097/Tp.0B013E3181684248 |
0.358 |
|
| 2008 |
Guo B, Chang EY, Cheng G. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. The Journal of Clinical Investigation. 118: 1680-90. PMID 18382764 DOI: 10.1172/Jci33342 |
0.624 |
|
| 2008 |
Wong PK, Yu F, Shahangian A, Cheng G, Sun R, Ho CM. Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm. Proceedings of the National Academy of Sciences of the United States of America. 105: 5105-10. PMID 18356295 DOI: 10.1073/Pnas.0800823105 |
0.749 |
|
| 2008 |
Velázquez P, Wei B, McPherson M, Mendoza LM, Nguyen SL, Turovskaya O, Kronenberg M, Huang TT, Schrage M, Lobato LN, Fujiwara D, Brewer S, Arditi M, Cheng G, Sartor RB, et al. Villous B cells of the small intestine are specialized for invariant NK T cell dependence. Journal of Immunology (Baltimore, Md. : 1950). 180: 4629-38. PMID 18354186 DOI: 10.4049/Jimmunol.180.7.4629 |
0.308 |
|
| 2008 |
Zarnegar B, Yamazaki S, He JQ, Cheng G. Control of canonical NF-kappaB activation through the NIK-IKK complex pathway. Proceedings of the National Academy of Sciences of the United States of America. 105: 3503-8. PMID 18292232 DOI: 10.1073/Pnas.0707959105 |
0.749 |
|
| 2008 |
Sanchez DJ, Miranda D, Arumugaswami V, Hwang S, Singer AE, Senaati A, Shahangian A, Song MJ, Sun R, Cheng G. A repetitive region of gammaherpesvirus genomic DNA is a ligand for induction of type I interferon. Journal of Virology. 82: 2208-17. PMID 18077715 DOI: 10.1128/Jvi.01718-07 |
0.789 |
|
| 2008 |
Oganesyan G, Saha SK, Pietras EM, Guo B, Miyahira AK, Zarnegar B, Cheng G. IRF3-dependent type I interferon response in B cells regulates CpG-mediated antibody production. The Journal of Biological Chemistry. 283: 802-8. PMID 17925397 DOI: 10.1074/Jbc.M704755200 |
0.803 |
|
| 2008 |
Cheng G, Zarnegar BJ, Wang Y, Mahoney DJ, Dempsey PW, Cheung HH, He J, Shiba T, Yang X, Yeh W, Mak TW, Korneluk RG. SY-8 Noncanonical NF-κB activation requires the coordinated assembly of the cIAP1/2-NIK regulatory complex by TRAF2 and TRAF3 Cytokine. 43: 236. DOI: 10.1016/J.Cyto.2008.07.039 |
0.717 |
|
| 2007 |
Lee DJ, Sieling PA, Ochoa MT, Krutzik SR, Guo B, Hernandez M, Rea TH, Cheng G, Colonna M, Modlin RL. LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 8128-36. PMID 18056355 DOI: 10.4049/Jimmunol.179.12.8128 |
0.361 |
|
| 2007 |
Kayagaki N, Phung Q, Chan S, Chaudhari R, Quan C, O'Rourke KM, Eby M, Pietras E, Cheng G, Bazan JF, Zhang Z, Arnott D, Dixit VM. DUBA: A deubiquitinase that regulates type I interferon production Science. 318: 1628-1632. PMID 17991829 DOI: 10.1126/Science.1145918 |
0.71 |
|
| 2007 |
Miller LS, Pietras EM, Uricchio LH, Hirano K, Rao S, Lin H, O'Connell RM, Iwakura Y, Cheung AL, Cheng G, Modlin RL. Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo. Journal of Immunology (Baltimore, Md. : 1950). 179: 6933-42. PMID 17982084 DOI: 10.4049/Jimmunol.179.10.6933 |
0.728 |
|
| 2007 |
He JQ, Oganesyan G, Saha SK, Zarnegar B, Cheng G. TRAF3 and its biological function. Advances in Experimental Medicine and Biology. 597: 48-59. PMID 17633016 DOI: 10.1007/978-0-387-70630-6_4 |
0.828 |
|
| 2007 |
Chang EY, Guo B, Doyle SE, Cheng G. Cutting edge: involvement of the type I IFN production and signaling pathway in lipopolysaccharide-induced IL-10 production. Journal of Immunology (Baltimore, Md. : 1950). 178: 6705-9. PMID 17513714 DOI: 10.4049/Jimmunol.178.11.6705 |
0.633 |
|
| 2007 |
Guo B, Cheng G. Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK. The Journal of Biological Chemistry. 282: 11817-26. PMID 17327220 DOI: 10.1074/Jbc.M700017200 |
0.511 |
|
| 2007 |
Chow EK, Razani B, Cheng G. Innate immune system regulation of nuclear hormone receptors in metabolic diseases. Journal of Leukocyte Biology. 82: 187-95. PMID 17314330 DOI: 10.1189/Jlb.1206741 |
0.755 |
|
| 2007 |
O'Connell RM, Taganov KD, Boldin MP, Cheng G, Baltimore D. MicroRNA-155 is induced during the macrophage inflammatory response. Proceedings of the National Academy of Sciences of the United States of America. 104: 1604-9. PMID 17242365 DOI: 10.1073/Pnas.0610731104 |
0.658 |
|
| 2007 |
He JQ, Saha SK, Kang JR, Zarnegar B, Cheng G. Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway. The Journal of Biological Chemistry. 282: 3688-94. PMID 17158868 DOI: 10.1074/Jbc.M610271200 |
0.798 |
|
| 2007 |
CHOW EK, CHU B, CHENG G, TAI Y, PIERSTORFF E, HO D. COPOLYMER-MEDIATED FABRICATION OF VERSATILE ELECTRO-ACTIVE AND INFLAMMATION ATTENUATING SUBSTRATES FOR BIOLOGICAL INTERROGATION Nano. 2: 351-359. DOI: 10.1142/S1793292007000696 |
0.483 |
|
| 2007 |
Chow EK, Pierstorff E, Cheng G, Tai YC, Ho D. Attenuation of cellular inflammation using glucocorticoid-functionalized copolymers Proceedings of the 2nd Ieee International Conference On Nano/Micro Engineered and Molecular Systems, Ieee Nems 2007. 1039-1043. DOI: 10.1109/NEMS.2007.352195 |
0.439 |
|
| 2007 |
Pietras EM, Saha SK, Miller LS, Uricchio LH, O’Connell RM, Iwakura Y, Cheung AL, Modlin RL, Cheng G. 121 Role of Myeloid Differentiation Factor 88-dependent Cytokines in Activation of Host Defense Functions Against Bacterial Infection Cytokine. 39: 33. DOI: 10.1016/J.Cyto.2007.07.126 |
0.671 |
|
| 2006 |
Chow EK, Castrillo A, Shahangian A, Pei L, O'Connell RM, Modlin RL, Tontonoz P, Cheng G. A role for IRF3-dependent RXRalpha repression in hepatotoxicity associated with viral infections. The Journal of Experimental Medicine. 203: 2589-602. PMID 17074929 DOI: 10.1084/Jem.20060929 |
0.818 |
|
| 2006 |
He JQ, Zarnegar B, Oganesyan G, Saha SK, Yamazaki S, Doyle SE, Dempsey PW, Cheng G. Rescue of TRAF3-null mice by p100 NF-kappa B deficiency. The Journal of Experimental Medicine. 203: 2413-8. PMID 17015635 DOI: 10.1084/Jem.20061166 |
0.813 |
|
| 2006 |
Pietras EM, Saha SK, Cheng G. The interferon response to bacterial and viral infections. Journal of Endotoxin Research. 12: 246-50. PMID 16953977 DOI: 10.1177/09680519060120040601 |
0.785 |
|
| 2006 |
Deng JC, Cheng G, Newstead MW, Zeng X, Kobayashi K, Flavell RA, Standiford TJ. Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M. The Journal of Clinical Investigation. 116: 2532-42. PMID 16917541 DOI: 10.1172/Jci28054 |
0.369 |
|
| 2006 |
Saha SK, Pietras EM, He JQ, Kang JR, Liu SY, Oganesyan G, Shahangian A, Zarnegar B, Shiba TL, Wang Y, Cheng G. Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif. The Embo Journal. 25: 3257-63. PMID 16858409 DOI: 10.1038/Sj.Emboj.7601220 |
0.792 |
|
| 2006 |
Renn CN, Sanchez DJ, Ochoa MT, Legaspi AJ, Oh CK, Liu PT, Krutzik SR, Sieling PA, Cheng G, Modlin RL. TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response. Journal of Immunology (Baltimore, Md. : 1950). 177: 298-305. PMID 16785525 DOI: 10.4049/Jimmunol.177.1.298 |
0.667 |
|
| 2006 |
Saha SK, Cheng G. TRAF3: a new regulator of type I interferons. Cell Cycle (Georgetown, Tex.). 5: 804-7. PMID 16582590 DOI: 10.4161/Cc.5.8.2637 |
0.632 |
|
| 2006 |
Miller LS, O'Connell RM, Gutierrez MA, Pietras EM, Shahangian A, Gross CE, Thirumala A, Cheung AL, Cheng G, Modlin RL. MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus. Immunity. 24: 79-91. PMID 16413925 DOI: 10.1016/J.Immuni.2005.11.011 |
0.789 |
|
| 2006 |
Oganesyan G, Saha SK, Guo B, He JQ, Shahangian A, Zarnegar B, Perry A, Cheng G. Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature. 439: 208-11. PMID 16306936 DOI: 10.1038/Nature04374 |
0.831 |
|
| 2005 |
Chow EK, O'connell RM, Schilling S, Wang XF, Fu XY, Cheng G. TLR agonists regulate PDGF-B production and cell proliferation through TGF-beta/type I IFN crosstalk. The Embo Journal. 24: 4071-81. PMID 16308570 DOI: 10.1038/Sj.Emboj.7600867 |
0.699 |
|
| 2005 |
Shen XD, Ke B, Zhai Y, Gao F, Busuttil RW, Cheng G, Kupiec-Weglinski JW. Toll-like receptor and heme oxygenase-1 signaling in hepatic ischemia/reperfusion injury. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5: 1793-800. PMID 15996225 DOI: 10.1111/J.1600-6143.2005.00932.X |
0.402 |
|
| 2005 |
Perry AK, Chen G, Zheng D, Tang H, Cheng G. The host type I interferon response to viral and bacterial infections. Cell Research. 15: 407-22. PMID 15987599 DOI: 10.1038/Sj.Cr.7290309 |
0.488 |
|
| 2005 |
O'Connell RM, Vaidya SA, Perry AK, Saha SK, Dempsey PW, Cheng G. Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1. Journal of Immunology (Baltimore, Md. : 1950). 174: 1602-7. PMID 15661922 DOI: 10.4049/Jimmunol.174.3.1602 |
0.841 |
|
| 2005 |
Liu B, Yang R, Wong KA, Getman C, Stein N, Teitell MA, Cheng G, Wu H, Shuai K. Negative regulation of NF-kappaB signaling by PIAS1. Molecular and Cellular Biology. 25: 1113-23. PMID 15657437 DOI: 10.1128/Mcb.25.3.1113-1123.2005 |
0.308 |
|
| 2005 |
O'Connell R, Saha S, Cheng G. Combating Bacterial Pathogens Through Host Defense Gene Programs Current Immunology Reviews. 1: 43-54. DOI: 10.2174/1573395052952950 |
0.657 |
|
| 2005 |
Chin AI, Dempsey PW, Cheng G. Rip2: A key molecule that regulates both innate and acquired immunity Current Medicinal Chemistry: Anti-Inflammatory and Anti-Allergy Agents. 4: 35-42. DOI: 10.2174/1568014053005264 |
0.759 |
|
| 2004 |
Ni CZ, Oganesyan G, Welsh K, Zhu X, Reed JC, Satterthwait AC, Cheng G, Ely KR. Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation. Journal of Immunology (Baltimore, Md. : 1950). 173: 7394-400. PMID 15585864 DOI: 10.4049/Jimmunol.173.12.7394 |
0.614 |
|
| 2004 |
Zhai Y, Shen XD, O'Connell R, Gao F, Lassman C, Busuttil RW, Cheng G, Kupiec-Weglinski JW. Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. Journal of Immunology (Baltimore, Md. : 1950). 173: 7115-9. PMID 15585830 DOI: 10.4049/Jimmunol.173.12.7115 |
0.64 |
|
| 2004 |
Modlin RL, Cheng G. From plankton to pathogen recognition. Nature Medicine. 10: 1173-4. PMID 15516915 DOI: 10.1038/Nm1104-1173 |
0.411 |
|
| 2004 |
Joseph SB, Bradley MN, Castrillo A, Bruhn KW, Mak PA, Pei L, Hogenesch J, O'connell RM, Cheng G, Saez E, Miller JF, Tontonoz P. LXR-dependent gene expression is important for macrophage survival and the innate immune response. Cell. 119: 299-309. PMID 15479645 DOI: 10.1016/J.Cell.2004.09.032 |
0.663 |
|
| 2004 |
O'Connell RM, Saha SK, Vaidya SA, Bruhn KW, Miranda GA, Zarnegar B, Perry AK, Nguyen BO, Lane TF, Taniguchi T, Miller JF, Cheng G. Type I interferon production enhances susceptibility to Listeria monocytogenes infection. The Journal of Experimental Medicine. 200: 437-45. PMID 15302901 DOI: 10.1084/Jem.20040712 |
0.808 |
|
| 2004 |
Perry AK, Chow EK, Goodnough JB, Yeh WC, Cheng G. Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection. The Journal of Experimental Medicine. 199: 1651-8. PMID 15210743 DOI: 10.1084/Jem.20040528 |
0.636 |
|
| 2004 |
Zarnegar B, He JQ, Oganesyan G, Hoffmann A, Baltimore D, Cheng G. Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-kappaB activation pathways. Proceedings of the National Academy of Sciences of the United States of America. 101: 8108-13. PMID 15148378 DOI: 10.1073/Pnas.0402629101 |
0.8 |
|
| 2004 |
Huerta-Yepez S, Vega M, Jazirehi A, Garban H, Hongo F, Cheng G, Bonavida B. Nitric oxide sensitizes prostate carcinoma cell lines to TRAIL-mediated apoptosis via inactivation of NF-kappa B and inhibition of Bcl-xl expression. Oncogene. 23: 4993-5003. PMID 15048072 DOI: 10.1038/Sj.Onc.1207655 |
0.347 |
|
| 2004 |
Doyle SE, O'Connell RM, Miranda GA, Vaidya SA, Chow EK, Liu PT, Suzuki S, Suzuki N, Modlin RL, Yeh WC, Lane TF, Cheng G. Toll-like receptors induce a phagocytic gene program through p38. The Journal of Experimental Medicine. 199: 81-90. PMID 14699082 DOI: 10.1084/Jem.20031237 |
0.823 |
|
| 2004 |
Jazirehi AR, Huerta-Yepez S, Cheng G, Bonavida B. Rituximab-Mediated Inhibition of the Constitutive NIK/IKK/IκB/NF-κB Signaling Pathway in Non-Hodgkin’s Lymphoma (NHL) B-Cell Lines: Role in Chemo-Sensitization. Blood. 104: 288-288. DOI: 10.1182/Blood.V104.11.288.288 |
0.408 |
|
| 2004 |
Zhai Y, Shen X, Gao F, OConnell R, Busuttil RW, Cheng G, Kupiec-Weglinski JW. THE TLR4 SIGNALING PATHWAY LINKS INNATE AND ADAPTIVE IMMUNITY IN LIVER ISCHEMIA AND REPERFUSION INJURY Transplantation. 78: 98-99. DOI: 10.1097/00007890-200407271-00266 |
0.34 |
|
| 2003 |
Dempsey PW, Vaidya SA, Cheng G. The art of war: Innate and adaptive immune responses. Cellular and Molecular Life Sciences : Cmls. 60: 2604-21. PMID 14685686 DOI: 10.1007/S00018-003-3180-Y |
0.743 |
|
| 2003 |
Castrillo A, Joseph SB, Vaidya SA, Haberland M, Fogelman AM, Cheng G, Tontonoz P. Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism. Molecular Cell. 12: 805-16. PMID 14580333 DOI: 10.1016/S1097-2765(03)00384-8 |
0.769 |
|
| 2003 |
Dadgostar H, Doyle SE, Shahangian A, Garcia DE, Cheng G. T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK(1). Febs Letters. 553: 403-7. PMID 14572659 DOI: 10.1016/S0014-5793(03)01072-X |
0.803 |
|
| 2003 |
Vaidya SA, Cheng G. Toll-like receptors and innate antiviral responses. Current Opinion in Immunology. 15: 402-7. PMID 12900271 DOI: 10.1016/S0952-7915(03)00070-0 |
0.78 |
|
| 2003 |
Brown HJ, Song MJ, Deng H, Wu TT, Cheng G, Sun R. NF-kappaB inhibits gammaherpesvirus lytic replication. Journal of Virology. 77: 8532-40. PMID 12857922 DOI: 10.1128/Jvi.77.15.8532-8540.2003 |
0.429 |
|
| 2003 |
Dempsey PW, Doyle SE, He JQ, Cheng G. The signaling adaptors and pathways activated by TNF superfamily. Cytokine & Growth Factor Reviews. 14: 193-209. PMID 12787559 DOI: 10.1016/S1359-6101(03)00021-2 |
0.448 |
|
| 2003 |
Doyle SE, O'Connell R, Vaidya SA, Chow EK, Yee K, Cheng G. Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4. Journal of Immunology (Baltimore, Md. : 1950). 170: 3565-71. PMID 12646618 DOI: 10.4049/Jimmunol.170.7.3565 |
0.825 |
|
| 2003 |
Ronni T, Agarwal V, Haykinson M, Haberland ME, Cheng G, Smale ST. Common interaction surfaces of the toll-like receptor 4 cytoplasmic domain stimulate multiple nuclear targets. Molecular and Cellular Biology. 23: 2543-55. PMID 12640135 DOI: 10.1128/Mcb.23.7.2543-2555.2003 |
0.667 |
|
| 2002 |
Doyle S, Vaidya S, O'Connell R, Dadgostar H, Dempsey P, Wu T, Rao G, Sun R, Haberland M, Modlin R, Cheng G. IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity. 17: 251-63. PMID 12354379 DOI: 10.1016/S1074-7613(02)00390-4 |
0.81 |
|
| 2002 |
Li C, Ni CZ, Havert ML, Cabezas E, He J, Kaiser D, Reed JC, Satterthwait AC, Cheng G, Ely KR. Downstream regulator TANK binds to the CD40 recognition site on TRAF3. Structure (London, England : 1993). 10: 403-11. PMID 12005438 DOI: 10.1016/S0969-2126(02)00733-5 |
0.534 |
|
| 2002 |
Chin AI, Dempsey PW, Bruhn K, Miller JF, Xu Y, Cheng G. Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature. 416: 190-4. PMID 11894097 DOI: 10.1038/416190A |
0.775 |
|
| 2002 |
Dadgostar H, Zarnegar B, Hoffmann A, Qin XF, Truong U, Rao G, Baltimore D, Cheng G. Cooperation of multiple signaling pathways in CD40-regulated gene expression in B lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 99: 1497-502. PMID 11830667 DOI: 10.1073/Pnas.032665099 |
0.798 |
|
| 2001 |
Kwan R, Burnside J, Kurosaki T, Cheng G. MEKK1 is essential for DT40 cell apoptosis in response to microtubule disruption Molecular and Cellular Biology. 21: 7183-7190. PMID 11585901 DOI: 10.1128/Mcb.21.21.7183-7190.2001 |
0.745 |
|
| 2001 |
Bleharski JR, Niazi KR, Sieling PA, Cheng G, Modlin RL. Signaling lymphocytic activation molecule is expressed on CD40 ligand-activated dendritic cells and directly augments production of inflammatory cytokines. Journal of Immunology (Baltimore, Md. : 1950). 167: 3174-81. PMID 11544303 DOI: 10.4049/Jimmunol.167.6.3174 |
0.386 |
|
| 2000 |
Dadgostar H, Cheng G. Membrane localization of TRAF 3 enables JNK activation. The Journal of Biological Chemistry. 275: 2539-44. PMID 10644711 DOI: 10.1074/Jbc.275.4.2539 |
0.773 |
|
| 1999 |
Chin AI, Shu J, Shan Shi C, Yao Z, Kehrl JH, Cheng G. TANK potentiates tumor necrosis factor receptor-associated factor-mediated c-Jun N-terminal kinase/stress-activated protein kinase activation through the germinal center kinase pathway. Molecular and Cellular Biology. 19: 6665-72. PMID 10490605 DOI: 10.1128/Mcb.19.10.6665 |
0.729 |
|
| 1999 |
Lee HH, Dadgostar H, Cheng Q, Shu J, Cheng G. NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 96: 9136-41. PMID 10430908 DOI: 10.1073/Pnas.96.16.9136 |
0.765 |
|
| 1999 |
Lee HH, Dempsey PW, Parks TP, Zhu X, Baltimore D, Cheng G. Specificities of CD40 signaling: involvement of TRAF2 in CD40-induced NF-kappaB activation and intercellular adhesion molecule-1 up-regulation. Proceedings of the National Academy of Sciences of the United States of America. 96: 1421-6. PMID 9990039 DOI: 10.1073/Pnas.96.4.1421 |
0.532 |
|
| 1998 |
Dadgostar H, Cheng G. An intact zinc ring finger is required for tumor necrosis factor receptor-associated factor-mediated nuclear factor-kappaB activation but is dispensable for c-Jun N-terminal kinase signaling. The Journal of Biological Chemistry. 273: 24775-80. PMID 9733779 DOI: 10.1074/Jbc.273.38.24775 |
0.787 |
|
| 1997 |
Rao G, Rekhtman N, Cheng G, Krasikov T, Skoultchi AI. Deregulated expression of the PU.1 transcription factor blocks murine erythroleukemia cell terminal differentiation. Oncogene. 14: 123-31. PMID 9010239 DOI: 10.1038/Sj.Onc.1200807 |
0.583 |
|
| 1996 |
Xu Y, Cheng G, Baltimore D. Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses Immunity. 5: 407-415. PMID 8934568 DOI: 10.1016/S1074-7613(00)80497-5 |
0.558 |
|
| 1996 |
Cheng G, Baltimore D. TANK, a co-inducer with TRAF2 of TNF-and CD40L-mediated NF-κB activation Genes and Development. 10: 963-973. PMID 8608943 |
0.301 |
|
| 1995 |
Alexandropoulos K, Cheng G, Baltimore D. Proline-rich sequences that bind to Src homology 3 domains with individual specificities. Proceedings of the National Academy of Sciences of the United States of America. 92: 3110-3114. PMID 7536925 DOI: 10.1073/Pnas.92.8.3110 |
0.445 |
|
| 1995 |
Cheng G, Cleary AM, Ye ZS, Hong DI, Lederman S, Baltimore D. Involvement of CRAF1, a relative of TRAF, in CD40 signaling. Science (New York, N.Y.). 267: 1494-8. PMID 7533327 DOI: 10.1126/Science.7533327 |
0.5 |
|
| 1995 |
Saksela K, Cheng G, Baltimore D. Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4. The Embo Journal. 14: 484-491. DOI: 10.1002/J.1460-2075.1995.Tb07024.X |
0.332 |
|
| 1994 |
Cheng G, Ye Z, Baltimore D. Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction Proceedings of the National Academy of Sciences of the United States of America. 91: 8152-8155. PMID 8058772 DOI: 10.1073/Pnas.91.17.8152 |
0.518 |
|
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