Mary M. Maleckar, Ph.D. - Publications

Affiliations: 
2008 Johns Hopkins University, Baltimore, MD 
Area:
Biomedical Engineering, Medical Biophysics

22/45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tveito A, Jæger KH, Maleckar MM, Giles WR, Wall S. Computational translation of drug effects from animal experiments to human ventricular myocytes. Scientific Reports. 10: 10537. PMID 32601303 DOI: 10.1038/S41598-020-66910-0  0.52
2018 Maleckar MM, Clark RB, Votta B, Giles WR. The Resting Potential and K Currents in Primary Human Articular Chondrocytes. Frontiers in Physiology. 9: 974. PMID 30233381 DOI: 10.3389/Fphys.2018.00974  0.52
2017 Belardinelli L, Maleckar MM, Giles WR. Ventricular Microanatomy, Arrhythmias, and the Electrochemical Driving Force for Na(+): Is There a Need for Flipped Learning? Circulation. Arrhythmia and Electrophysiology. 10: e004955. PMID 28213509 DOI: 10.1161/Circep.117.004955  0.52
2014 Maleckar MM, Lines GT, Koivumäki JT, Cordeiro JM, Calloe K. NS5806 partially restores action potential duration but fails to ameliorate calcium transient dysfunction in a computational model of canine heart failure. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 16: iv46-iv55. PMID 25362170 DOI: 10.1093/Europace/Euu252  1
2014 Koivumäki JT, Clark RB, Belke D, Kondo C, Fedak PW, Maleckar MM, Giles WR. Na(+) current expression in human atrial myofibroblasts: identity and functional roles. Frontiers in Physiology. 5: 275. PMID 25147525 DOI: 10.3389/fphys.2014.00275  1
2014 Frisk M, Koivumäki JT, Norseng PA, Maleckar MM, Sejersted OM, Louch WE. Variable t-tubule organization and Ca2+ homeostasis across the atria. American Journal of Physiology. Heart and Circulatory Physiology. 307: H609-20. PMID 24951751 DOI: 10.1152/ajpheart.00295.2014  1
2014 Koivumäki JT, Seemann G, Maleckar MM, Tavi P. In silico screening of the key cellular remodeling targets in chronic atrial fibrillation. Plos Computational Biology. 10: e1003620. PMID 24853123 DOI: 10.1371/Journal.Pcbi.1003620  1
2012 Wilhelms M, Hettmann H, Maleckar MM, Koivumäki JT, Dössel O, Seemann G. Benchmarking electrophysiological models of human atrial myocytes. Frontiers in Physiology. 3: 487. PMID 23316167 DOI: 10.3389/fphys.2012.00487  1
2012 Rose RA, Belke DD, Maleckar MM, Giles WR. Ca(2+) entry through TRP-C channels regulates fibroblast biology in chronic atrial fibrillation. Circulation. 126: 2039-41. PMID 23091082 DOI: 10.1161/Circulationaha.112.138065  1
2012 Tveito A, Lines GT, Edwards AG, Maleckar MM, Michailova A, Hake J, McCulloch A. Slow Calcium-Depolarization-Calcium waves may initiate fast local depolarization waves in ventricular tissue Progress in Biophysics and Molecular Biology. 110: 295-304. PMID 22841534 DOI: 10.1016/J.Pbiomolbio.2012.07.005  1
2012 Tveito A, Lines GT, Maleckar MM. Note on a possible proarrhythmic property of antiarrhythmic drugs aimed at improving gap-junction coupling. Biophysical Journal. 102: 231-7. PMID 22339859 DOI: 10.1016/J.Bpj.2011.11.4015  1
2012 Koivumaki JT, Christ T, Seemann G, Maleckar MM. Divergent action potential morphology in human atrial cells compared with tissue: Underlying ionic mechanisms Computing in Cardiology. 39: 121-124.  1
2011 Niederer SA, Kerfoot E, Benson AP, Bernabeu MO, Bernus O, Bradley C, Cherry EM, Clayton R, Fenton FH, Garny A, Heidenreich E, Land S, Maleckar M, Pathmanathan P, Plank G, et al. Verification of cardiac tissue electrophysiology simulators using an N-version benchmark. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 369: 4331-51. PMID 21969679 DOI: 10.1098/Rsta.2011.0139  1
2011 McDowell KS, Arevalo HJ, Maleckar MM, Trayanova NA. Susceptibility to arrhythmia in the infarcted heart depends on myofibroblast density. Biophysical Journal. 101: 1307-15. PMID 21943411 DOI: 10.1016/J.Bpj.2011.08.009  1
2011 Tveito A, Lines G, Skavhaug O, Maleckar MM. Unstable eigenmodes are possible drivers for cardiac arrhythmias. Journal of the Royal Society, Interface / the Royal Society. 8: 1212-6. PMID 21571942 DOI: 10.1098/Rsif.2011.0152  1
2011 Tveito A, Lines G, Artebrant R, Skavhaug O, Maleckar MM. Existence of excitation waves for a collection of cardiomyocytes electrically coupled to fibroblasts. Mathematical Biosciences. 230: 79-86. PMID 21296091 DOI: 10.1016/J.Mbs.2011.01.004  1
2009 Maleckar MM, Greenstein JL, Giles WR, Trayanova NA. Electrotonic coupling between human atrial myocytes and fibroblasts alters myocyte excitability and repolarization. Biophysical Journal. 97: 2179-90. PMID 19843450 DOI: 10.1016/J.Bpj.2009.07.054  1
2009 Maleckar MM, Greenstein JL, Giles WR, Trayanova NA. K+ current changes account for the rate dependence of the action potential in the human atrial myocyte. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1398-410. PMID 19633207 DOI: 10.1152/Ajpheart.00411.2009  1
2008 Maleckar MM, Greenstein JL, Trayanova NA, Giles WR. Mathematical simulations of ligand-gated and cell-type specific effects on the action potential of human atrium. Progress in Biophysics and Molecular Biology. 98: 161-70. PMID 19186188 DOI: 10.1016/J.Pbiomolbio.2009.01.010  1
2008 Maleckar MM, Woods MC, Sidorov VY, Holcomb MR, Mashburn DN, Wikswo JP, Trayanova NA. Polarity reversal lowers activation time during diastolic field stimulation of the rabbit ventricles: insights into mechanisms. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1626-33. PMID 18708441 DOI: 10.1152/Ajpheart.00706.2008  1
2006 Gurev V, Maleckar MM, Trayanova NA. Cardiac defibrillation and the role of mechanoelectric feedback in postshock arrhythmogenesis. Annals of the New York Academy of Sciences. 1080: 320-33. PMID 17132792 DOI: 10.1196/Annals.1380.024  1
2006 Bourn DW, Maleckar MM, Rodriguez B, Trayanova NA. Mechanistic enquiry into the effect of increased pacing rate on the upper limit of vulnerability. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 364: 1333-48. PMID 16766348 DOI: 10.1098/Rsta.2006.1775  1
Low-probability matches
2017 Vagos MR, Arevalo H, de Oliveira BL, Sundnes J, Maleckar MM. A computational framework for testing arrhythmia marker sensitivities to model parameters in functionally calibrated populations of atrial cells. Chaos (Woodbury, N.Y.). 27: 093941. PMID 28964122 DOI: 10.1063/1.4999476  0.12
2021 Hicks SA, Isaksen JL, Thambawita V, Ghouse J, Ahlberg G, Linneberg A, Grarup N, Strümke I, Ellervik C, Olesen MS, Hansen T, Graff C, Holstein-Rathlou NH, Halvorsen P, Maleckar MM, et al. Explaining deep neural networks for knowledge discovery in electrocardiogram analysis. Scientific Reports. 11: 10949. PMID 34040033 DOI: 10.1038/s41598-021-90285-5  0.01
2019 Jæger KH, Charwat V, Charrez B, Finsberg H, Maleckar MM, Wall S, Healy KE, Tveito A. Improved Computational Identification of Drug Response Using Optical Measurements of Human Stem Cell Derived Cardiomyocytes in Microphysiological Systems. Frontiers in Pharmacology. 10: 1648. PMID 32116671 DOI: 10.3389/Fphar.2019.01648  0.01
2019 Vasan R, Maleckar MM, Williams CD, Rangamani P. DLITE Uses Cell-Cell Interface Movement to Better Infer Cell-Cell Tensions. Biophysical Journal. PMID 31648791 DOI: 10.1016/J.Bpj.2019.09.034  0.01
2019 Vasan R, Williams CD, Maleckar MM, Rangamani P. Inferring Cell Colony Forces across Time from Tight Junction Intersections in Human Induced Pluripotent Stem Cells Biophysical Journal. 116: 18a. DOI: 10.1016/J.Bpj.2018.11.141  0.01
2018 Ounkomol C, Seshamani S, Maleckar MM, Collman F, Johnson GR. Label-free prediction of three-dimensional fluorescence images from transmitted-light microscopy. Nature Methods. PMID 30224672 DOI: 10.1038/S41592-018-0111-2  0.01
2018 Tveito A, Maleckar MM, Lines GT. Computing Optimal Properties of Drugs Using Mathematical Models of Single Channel Dynamics Computational and Mathematical Biophysics. 6: 41-64. DOI: 10.1515/cmb-2018-0004  0.01
2018 Vagos MR, Heijman J, Arevalo H, Maleckar MM, Lino de Oliveira B, Schotten U, Sundnes J. A Novel Computational Model of the Rabbit Atrial Myocyte Offers Insight into Calcium Wave Propagation Failure Biophysical Journal. 114: 119a. DOI: 10.1016/J.Bpj.2017.11.680  0.01
2018 Johnson G, Donovan-Maiye R, Ounkomol C, Maleckar MM. Studying Stem Cell Organization using “Label-Free” Methods and a Novel Generative Adversarial Model Biophysical Journal. 114: 43a. DOI: 10.1016/J.Bpj.2017.11.284  0.01
2018 Morotti S, Ellinwood N, Ni H, Koivumäki JT, Maleckar MM, Heijman J, Dobrev D, Grandi E. Effects of Modulation of Small-Conductance Calcium-Activated Potassium Current on Atrial Electrophysiology and Arrhythmogenesis: A Population-Based Computational Study Biophysical Journal. 114: 473a. DOI: 10.1016/J.Bpj.2017.11.2604  0.01
2018 van Herck I, Bentzen BH, Seutin V, Arevalo H, Maleckar MM, Marrion NV, Edwards AG. Model Development of SK Channel Gating Incorporating Calcium Sensitivity and Drug Interaction Biophysical Journal. 114: 306a. DOI: 10.1016/J.Bpj.2017.11.1735  0.01
2017 Behdadfar S, Navarro L, Sundnes J, Maleckar M, Ross S, Odland HH, Avril S. A Centerline Based Model Morphing Algorithm for Patient-Specific Finite Element Modelling of the Left Ventricle. Ieee Transactions On Bio-Medical Engineering. PMID 28945587 DOI: 10.1109/Tbme.2017.2754980  0.01
2017 Kallhovd S, Maleckar MM, Rognes ME. Inverse estimation of cardiac activation times via gradient-based optimisation. International Journal For Numerical Methods in Biomedical Engineering. PMID 28744962 DOI: 10.1002/Cnm.2919  0.01
2017 Maleckar MM, Edwards AG, Louch WE, Lines GT. Studying dyadic structure-function relationships: a review of current modeling approaches and new insights into Ca(2+) (mis)handling. Clinical Medicine Insights. Cardiology. 11: 1179546817698602. PMID 28469494 DOI: 10.1177/1179546817698602  0.01
2017 Lines GT, de Oliveira BL, Skavhaug O, Maleckar MM. Simple T-Wave Metrics May Better Predict Early Ischemia as Compared to ST Segment. Ieee Transactions On Bio-Medical Engineering. 64: 1305-1309. PMID 27576235 DOI: 10.1109/Tbme.2016.2600198  0.01
2017 E. Rognes M, E. Farrell P, W. Funke S, E. Hake J, M. C. Maleckar M. cbcbeat: an adjoint-enabled framework for computational cardiac electrophysiology The Journal of Open Source Software. 2: 224. DOI: 10.21105/joss.00224  0.01
2016 Skibsbye L, Jespersen T, Christ T, Maleckar MM, van den Brink J, Tavi P, Koivumäki JT. Refractoriness in human atria: Time and voltage dependence of sodium channel availability. Journal of Molecular and Cellular Cardiology. PMID 27773652 DOI: 10.1016/J.Yjmcc.2016.10.009  0.01
2016 Grandi E, Maleckar MM. Anti-arrhythmic strategies for atrial fibrillation: The role of computational modeling in discovery, development, and optimization. Pharmacology & Therapeutics. PMID 27612549 DOI: 10.1016/J.Pharmthera.2016.09.012  0.01
2016 Morotti S, Koivumäki JT, Maleckar MM, Chiamvimonvat N, Grandi E. Small-Conductance Ca2+-Activated K+ Current in Atrial Fibrillation: Both Friend and FOE Biophysical Journal. 110: 274a. DOI: 10.1016/J.Bpj.2015.11.1487  0.01
2013 Li P, Lines GT, Maleckar MM, Tveito A. Mathematical models of cardiac pacemaking function Frontiers in Physics. 1. DOI: 10.3389/Fphy.2013.00020  0.01
2006 Maleckar MM, Blake RC, Trayanova NA. P3-27 Heart Rhythm. 3: S187. DOI: 10.1016/J.Hrthm.2006.02.559  0.01
2006 Woods MC, Maleckar MM, Sidorov VY, Holcomb MR, Mashburn DN, Trayanova NA, Wikswo JP. P3-12 Heart Rhythm. 3: S181-S182. DOI: 10.1016/J.Hrthm.2006.02.544  0.01
2005 Maleckar MM, Bourn DW, Rodriguez B, Trayanova NA. Mechanistic insight into the increase in the upper limit of vulnerability for rapid pacing Heart Rhythm. 2: S219. DOI: 10.1016/J.Hrthm.2005.02.684  0.01
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