James A. Hoxie - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Microbiology Biology

180 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Melton A, Rowe LA, Penney T, Krzykwa C, Goff K, Scheuermann S, Melton HJ, Williams K, Golden N, Green KM, Smith B, Russell-Lodrigue K, Dufour JP, Doyle-Meyers LA, Schiro F, ... ... Hoxie JA, et al. The Impact of SIV-Induced Immunodeficiency on Clinical Manifestation, Immune Response, and Viral Dynamics in SARS-CoV-2 Coinfection. Biorxiv : the Preprint Server For Biology. PMID 38014096 DOI: 10.1101/2023.11.15.567132  0.376
2022 Addison MM, Ellis GI, Leslie GJ, Zawadzky NB, Riley JL, Hoxie JA, Eisenlohr LC. HIV-1-Infected CD4 T Cells Present MHC Class II-Restricted Epitope via Endogenous Processing. Journal of Immunology (Baltimore, Md. : 1950). 209: 864-873. PMID 36130133 DOI: 10.4049/jimmunol.2200145  0.773
2022 Lawrence SP, Elser SE, Torben W, Blair RV, Pahar B, Aye PP, Schiro F, Szeltner D, Doyle-Meyers LA, Haggarty BS, Jordan APO, Romano J, Leslie GJ, Alvarez X, O'Connor DH, ... ... Hoxie JA, et al. A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection. Plos Pathogens. 18: e1010507. PMID 35714165 DOI: 10.1371/journal.ppat.1010507  0.725
2022 Welles HC, King HAD, Nettey L, Cavett N, Gorman J, Zhou T, Tsybovsky Y, Du R, Song K, Nguyen R, Ambrozak D, Ransier A, Schramm CA, Doria-Rose NA, Swanstrom AE, ... Hoxie JA, et al. Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4. Plos Pathogens. 18: e1010574. PMID 35709309 DOI: 10.1371/journal.ppat.1010574  0.386
2021 Melton A, Doyle-Meyers LA, Blair RV, Midkiff C, Melton HJ, Russell-Lodrigue K, Aye PP, Schiro F, Fahlberg M, Szeltner D, Spencer S, Beddingfield BJ, Goff K, Golden N, Penney T, ... ... Hoxie JA, et al. The pigtail macaque (Macaca nemestrina) model of COVID-19 reproduces diverse clinical outcomes and reveals new and complex signatures of disease. Plos Pathogens. 17: e1010162. PMID 34929014 DOI: 10.1371/journal.ppat.1010162  0.301
2020 Maldini CR, Claiborne DT, Okawa K, Chen T, Dopkin DL, Shan X, Power KA, Trifonova RT, Krupp K, Phelps M, Vrbanac VD, Tanno S, Bateson T, Leslie GJ, Hoxie JA, et al. Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo. Nature Medicine. PMID 32868878 DOI: 10.1038/S41591-020-1039-5  0.792
2020 Schouest B, Leslie GJ, Hoxie JA, Maness NJ. Tetherin downmodulation by SIVmac Nef lost with the H196Q escape variant is restored by an upstream variant. Plos One. 15: e0225420. PMID 32764749 DOI: 10.1371/Journal.Pone.0225420  0.753
2019 Nguyen S, Deleage C, Darko S, Ransier A, Truong DP, Agarwal D, Japp AS, Wu VH, Kuri-Cervantes L, Abdel-Mohsen M, Del Rio Estrada PM, Ablanedo-Terrazas Y, Gostick E, Hoxie JA, Zhang NR, et al. Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8 T cells. Science Translational Medicine. 11. PMID 31852798 DOI: 10.1126/Scitranslmed.Aax4077  0.558
2019 Bucşan AN, Chatterjee A, Singh DK, Foreman TW, Lee TH, Threeton B, Kirkpatrick MG, Ahmed M, Golden N, Alvarez X, Hoxie JA, Mehra S, Rengarajan J, Khader SA, Kaushal D. Mechanisms of reactivation of latent tuberculosis infection due to SIV co-infection. The Journal of Clinical Investigation. PMID 31479428 DOI: 10.1172/Jci125810  0.499
2018 Janaka SK, Tavakoli-Tameh A, Neidermyer WJ, Serra-Moreno R, Hoxie JA, Desrosiers RC, Johnson RP, Lifson JD, Wolinsky SM, Evans DT. Polymorphisms in Rhesus Macaque Tetherin are Associated with Differences in Acute Viremia in SIV Δ-Infected Animals. Journal of Virology. PMID 30135127 DOI: 10.1128/Jvi.00542-18  0.364
2018 Salantes DB, Zheng Y, Mampe F, Srivastava T, Beg S, Lai J, Li JZ, Tressler RL, Koup RA, Hoxie J, Abdel-Mohsen M, Sherrill-Mix S, McCormick K, Overton ET, Bushman FD, et al. HIV-1 latent reservoir size and diversity are stable following brief treatment interruption. The Journal of Clinical Investigation. PMID 29911997 DOI: 10.1172/Jci120194  0.445
2017 Hogan MJ, Conde-Motter A, Jordan APO, Yang L, Cleveland B, Guo W, Romano J, Ni H, Pardi N, LaBranche CC, Montefiori DC, Hu SL, Hoxie JA, Weissman D. Increased surface expression of HIV-1 envelope is associated with improved antibody response in vaccinia prime/protein boost immunization. Virology. 514: 106-117. PMID 29175625 DOI: 10.1016/J.Virol.2017.10.013  0.483
2017 Swanstrom AE, Del Prete GQ, Deleage C, Elser SE, Lackner AA, Hoxie JA. The SIV Envelope Glycoprotein, Viral Tropism, and Pathogenesis: Novel Insights from Nonhuman Primate Models of AIDS`. Current Hiv Research. PMID 29173176 DOI: 10.2174/1570162X15666171124123116  0.778
2017 Moy RH, Huffman AP, Richman LP, Crisalli L, Wang XK, Hoxie JA, Mick R, Emerson SG, Zhang Y, Vonderheide RH, Porter DL, Reshef R. Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis. Blood. PMID 28057639 DOI: 10.1182/Blood-2016-08-735076  0.327
2016 Bar KJ, Sneller MC, Harrison LJ, Justement JS, Overton ET, Petrone ME, Salantes DB, Seamon CA, Scheinfeld B, Kwan RW, Learn GH, Proschan MA, Kreider EF, Blazkova J, Bardsley M, ... ... Hoxie JA, et al. Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption. The New England Journal of Medicine. 375: 2037-2050. PMID 27959728 DOI: 10.1056/Nejmoa1608243  0.475
2016 Leslie GJ, Wang J, Richardson MW, Haggarty BS, Hua KL, Duong J, Secreto AJ, Jordon AP, Romano J, Kumar KE, DeClercq JJ, Gregory PD, June CH, Root MJ, Riley JL, ... ... Hoxie JA, et al. Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus. Plos Pathogens. 12: e1005983. PMID 27855210 DOI: 10.1371/Journal.Ppat.1005983  0.806
2016 Tsao LC, Guo H, Jeffrey J, Hoxie JA, Su L. CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo. Retrovirology. 13: 22. PMID 27026376 DOI: 10.1186/S12977-016-0255-Z  0.59
2016 Swanstrom AE, Haggarty B, Jordan AP, Romano J, Leslie GJ, Aye PP, Marx PA, Lackner AA, Del Prete GQ, Robinson JE, Betts MR, Montefiori DC, LaBranche CC, Hoxie JA. Derivation and characterization of a CD4-independent, non-CD4 tropic simian immunodeficiency virus. Journal of Virology. PMID 26937037 DOI: 10.1128/Jvi.02851-15  0.808
2016 Leslie GJ, Richardson M, Wang J, Gregory P, Riley J, Holmes M, Hoxie J. 427. In Vivo Inhibition of HIV-1 in NSG Mice After Transduction of Primary Human T Cells with CXCR4 Conjugated to an HR2 Peptide Molecular Therapy. 24: S169. DOI: 10.1016/S1525-0016(16)33236-1  0.798
2015 Breed MW, Elser SE, Torben W, Jordan AP, Aye PP, Midkiff C, Schiro F, Sugimoto C, Alvarez-Hernandez X, Blair RV, Somasunderam A, Utay NS, Kuroda MJ, Pahar B, Wiseman RW, ... ... Hoxie JA, et al. Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif. Journal of Virology. 89: 10156-75. PMID 26223646 DOI: 10.1128/Jvi.01134-15  0.491
2015 Santangelo PJ, Rogers KA, Zurla C, Blanchard EL, Gumber S, Strait K, Connor-Stroud F, Schuster DM, Amancha PK, Hong JJ, Byrareddy SN, Hoxie JA, Vidakovic B, Ansari AA, Hunter E, et al. Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy-treated macaques. Nature Methods. 12: 427-32. PMID 25751144 DOI: 10.1038/Nmeth.3320  0.427
2015 Boyd DF, Peterson D, Haggarty BS, Jordan AP, Hogan MJ, Goo L, Hoxie JA, Overbaugh J. Mutations in HIV-1 envelope that enhance entry with the macaque CD4 receptor alter antibody recognition by disrupting quaternary interactions within the trimer. Journal of Virology. 89: 894-907. PMID 25378497 DOI: 10.1128/Jvi.02680-14  0.597
2015 Moy RH, Huffman AP, Richman LP, Crisalli L, Hoxie JA, Vonderheide RH, Porter DL, Reshef R. Immunologic Effects of CCR5 Blockade in Graft-Versus-Host Disease Prophylaxis Blood. 126: 920-920. DOI: 10.1182/Blood.V126.23.920.920  0.386
2014 Pegu A, Yang ZY, Boyington JC, Wu L, Ko SY, Schmidt SD, McKee K, Kong WP, Shi W, Chen X, Todd JP, Letvin NL, Huang J, Nason MC, Hoxie JA, et al. Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor. Science Translational Medicine. 6: 243ra88. PMID 24990883 DOI: 10.1126/Scitranslmed.3008992  0.578
2014 Yen PJ, Mefford ME, Hoxie JA, Williams KC, Desrosiers RC, Gabuzda D. Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques. Virology. 458: 53-68. PMID 24928039 DOI: 10.1016/J.Virol.2014.03.024  0.376
2014 Joseph SB, Arrildt KT, Swanstrom AE, Schnell G, Lee B, Hoxie JA, Swanstrom R. Quantification of entry phenotypes of macrophage-tropic HIV-1 across a wide range of CD4 densities. Journal of Virology. 88: 1858-69. PMID 24307580 DOI: 10.1128/Jvi.02477-13  0.573
2013 Bastian AR, Contarino M, Bailey LD, Aneja R, Moreira DRM, Freedman K, McFadden K, Duffy C, Emileh A, Leslie G, Jacobson JM, Hoxie JA, Chaiken I. Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions Retrovirology. 10. PMID 24330857 DOI: 10.1186/1742-4690-10-153  0.787
2013 Breed MW, Jordan AP, Aye PP, Sugimoto C, Alvarez X, Kuroda MJ, Pahar B, Keele BF, Hoxie JA, Lackner AA. A single amino acid mutation in the envelope cytoplasmic tail restores the ability of an attenuated simian immunodeficiency virus mutant to deplete mucosal CD4+ T cells. Journal of Virology. 87: 13048-52. PMID 24027336 DOI: 10.1128/Jvi.02126-13  0.488
2013 Francella N, Gwyn SE, Yi Y, Li B, Xiao P, Elliott ST, Ortiz AM, Hoxie JA, Paiardini M, Silvestri G, Derdeyn CA, Collman RG. CD4+ T cells support production of simian immunodeficiency virus Env antibodies that enforce CD4-dependent entry and shape tropism in vivo. Journal of Virology. 87: 9719-32. PMID 23824793 DOI: 10.1128/Jvi.01254-13  0.478
2013 Curran JW, Hoxie JA. Translating social and behavioral science research to the AIDS epidemic: a center for AIDS research perspective. Journal of Acquired Immune Deficiency Syndromes (1999). 63: S4-5. PMID 23673885 DOI: 10.1097/Qai.0B013E3182921525  0.349
2013 Breed MW, Jordan AP, Aye PP, Lichtveld CF, Midkiff CC, Schiro FR, Haggarty BS, Sugimoto C, Alvarez X, Sandler NG, Douek DC, Kuroda MJ, Pahar B, Piatak M, Lifson JD, ... ... Hoxie JA, et al. Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression. Journal of Virology. 87: 1528-43. PMID 23152518 DOI: 10.1128/Jvi.01928-12  0.511
2012 Hoxie JA, June CH. Novel cell and gene therapies for HIV. Cold Spring Harbor Perspectives in Medicine. 2. PMID 23028130 DOI: 10.1101/Cshperspect.A007179  0.502
2012 Wu X, Wang C, O'Dell S, Li Y, Keele BF, Yang Z, Imamichi H, Doria-Rose N, Hoxie JA, Connors M, Shaw GM, Wyatt RT, Mascola JR. Selection pressure on HIV-1 envelope by broadly neutralizing antibodies to the conserved CD4-binding site. Journal of Virology. 86: 5844-56. PMID 22419808 DOI: 10.1128/Jvi.07139-11  0.523
2011 Hijazi K, Wang Y, Scala C, Jeffs S, Longstaff C, Stieh D, Haggarty B, Vanham G, Schols D, Balzarini J, Jones IM, Hoxie J, Shattock R, Kelly CG. DC-SIGN increases the affinity of HIV-1 envelope glycoprotein interaction with CD4. Plos One. 6: e28307. PMID 22163292 DOI: 10.1371/Journal.Pone.0028307  0.497
2011 White TA, Bartesaghi A, Borgnia MJ, de la Cruz MJ, Nandwani R, Hoxie JA, Bess JW, Lifson JD, Milne JL, Subramaniam S. Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography. Journal of Virology. 85: 12114-23. PMID 21937655 DOI: 10.1128/Jvi.05297-11  0.559
2011 Acharya P, Dogo-Isonagie C, LaLonde JM, Lam SN, Leslie GJ, Louder MK, Frye LL, Debnath AK, Greenwood JR, Luongo TS, Martin L, Watts KS, Hoxie JA, Mascola JR, Bewley CA, et al. Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry. Acs Chemical Biology. 6: 1069-77. PMID 21793507 DOI: 10.1021/Cb200068B  0.802
2011 Pollara J, Hart L, Brewer F, Pickeral J, Packard BZ, Hoxie JA, Komoriya A, Ochsenbauer C, Kappes JC, Roederer M, Huang Y, Weinhold KJ, Tomaras GD, Haynes BF, Montefiori DC, et al. High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 603-12. PMID 21735545 DOI: 10.1002/Cyto.A.21084  0.543
2011 Ferrari G, Pollara J, Kozink D, Harms T, Drinker M, Freel S, Moody MA, Alam SM, Tomaras GD, Ochsenbauer C, Kappes JC, Shaw GM, Hoxie JA, Robinson JE, Haynes BF. An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum. Journal of Virology. 85: 7029-36. PMID 21543485 DOI: 10.1128/Jvi.00171-11  0.554
2011 Wilen CB, Wang J, Tilton JC, Miller JC, Kim KA, Rebar EJ, Sherrill-Mix SA, Patro SC, Secreto AJ, Jordan AP, Lee G, Kahn J, Aye PP, Bunnell BA, Lackner AA, ... Hoxie JA, et al. Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases. Plos Pathogens. 7: e1002020. PMID 21533216 DOI: 10.1371/Journal.Ppat.1002020  0.591
2011 Pilch-Cooper HA, Sieg SF, Hope TJ, Koons A, Escola JM, Offord R, Veazey RS, Mosier DE, Clagett B, Medvik K, Jadlowsky JK, Chance MR, Kiselar JG, Hoxie JA, Collman RG, et al. Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5. Blood. 118: 1015-9. PMID 21068438 DOI: 10.1182/Blood-2010-05-282509  0.497
2011 Tebas P, Wilsen C, Doms R, Hoxie J, Gregory P, Holmes M, June C. 176 Exploring the Potential of CCR5 and CXCR4 Modified CD4 T Cells to Target the HIV-1 Reservoir Jaids Journal of Acquired Immune Deficiency Syndromes. 56: 73. DOI: 10.1097/01.Qai.0000397359.53545.66  0.517
2010 White TA, Bartesaghi A, Borgnia MJ, Meyerson JR, de la Cruz MJ, Bess JW, Nandwani R, Hoxie JA, Lifson JD, Milne JL, Subramaniam S. Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure. Plos Pathogens. 6: e1001249. PMID 21203482 DOI: 10.1371/Journal.Ppat.1001249  0.606
2010 Del Prete GQ, Leslie GJ, Haggarty B, Jordan AP, Romano J, Hoxie JA. Distinct molecular pathways to X4 tropism for a V3-truncated human immunodeficiency virus type 1 lead to differential coreceptor interactions and sensitivity to a CXCR4 antagonist. Journal of Virology. 84: 8777-89. PMID 20573813 DOI: 10.1128/Jvi.00333-10  0.811
2010 Hoxie JA. Toward an antibody-based HIV-1 vaccine. Annual Review of Medicine. 61: 135-52. PMID 19824826 DOI: 10.1146/Annurev.Med.60.042507.164323  0.458
2010 Reshef R, Luger SM, Loren AW, Frey NV, Goldstein SC, Hexner EO, Stadtmauer EA, Smith J, Mick R, Heitjan DF, Shetzline SE, Danet-Desnoyers GH, Emerson SG, Hoxie JA, Vonderheide RH, et al. Prevention of Graft-Versus-Host Disease by Inhibition of Lymphocyte Trafficking Using a CCR5 Antagonist Blood. 116: 673-673. DOI: 10.1182/Blood.V116.21.673.673  0.35
2009 Dosenovic P, Chakrabarti B, Soldemo M, Douagi I, Forsell MN, Li Y, Phogat A, Paulie S, Hoxie J, Wyatt RT, Karlsson Hedestam GB. Selective expansion of HIV-1 envelope glycoprotein-specific B cell subsets recognizing distinct structural elements following immunization. Journal of Immunology (Baltimore, Md. : 1950). 183: 3373-82. PMID 19696434 DOI: 10.4049/Jimmunol.0900407  0.435
2009 Agrawal-Gamse C, Lee FH, Haggarty B, Jordan AP, Yi Y, Lee B, Collman RG, Hoxie JA, Doms RW, Laakso MM. Adaptive mutations in a human immunodeficiency virus type 1 envelope protein with a truncated V3 loop restore function by improving interactions with CD4. Journal of Virology. 83: 11005-15. PMID 19692476 DOI: 10.1128/Jvi.01238-09  0.572
2009 Del Prete GQ, Haggarty B, Leslie GJ, Jordan AP, Romano J, Wang N, Wang J, Holmes MC, Montefiori DC, Hoxie JA. Derivation and characterization of a simian immunodeficiency virus SIVmac239 variant with tropism for CXCR4. Journal of Virology. 83: 9911-22. PMID 19605489 DOI: 10.1128/Jvi.00533-09  0.842
2009 Wu L, Zhou T, Yang ZY, Svehla K, O'Dell S, Louder MK, Xu L, Mascola JR, Burton DR, Hoxie JA, Doms RW, Kwong PD, Nabel GJ. Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain. Journal of Virology. 83: 5077-86. PMID 19264769 DOI: 10.1128/Jvi.02600-08  0.501
2009 Nolan KM, Del Prete GQ, Jordan AP, Haggarty B, Romano J, Leslie GJ, Hoxie JA. Characterization of a human immunodeficiency virus type 1 V3 deletion mutation that confers resistance to CCR5 inhibitors and the ability to use aplaviroc-bound receptor. Journal of Virology. 83: 3798-809. PMID 19193800 DOI: 10.1128/Jvi.01751-08  0.8
2009 Davis KL, Bibollet-Ruche F, Li H, Decker JM, Kutsch O, Morris L, Salomon A, Pinter A, Hoxie JA, Hahn BH, Kwong PD, Shaw GM. Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1 V3-specific antibodies in human plasma. Journal of Virology. 83: 1240-59. PMID 19019969 DOI: 10.1128/Jvi.01743-08  0.57
2009 Li Y, Svehla K, Louder MK, Wycuff D, Phogat S, Tang M, Migueles SA, Wu X, Phogat A, Shaw GM, Connors M, Hoxie J, Mascola JR, Wyatt R. Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals. Journal of Virology. 83: 1045-59. PMID 19004942 DOI: 10.1128/Jvi.01992-08  0.576
2008 Fauci AS, Johnston MI, Dieffenbach CW, Burton DR, Hammer SM, Hoxie JA, Martin M, Overbaugh J, Watkins DI, Mahmoud A, Greene WC. HIV vaccine research: the way forward. Science (New York, N.Y.). 321: 530-2. PMID 18653883 DOI: 10.1126/Science.1161000  0.369
2008 Crooks ET, Jiang P, Franti M, Wong S, Zwick MB, Hoxie JA, Robinson JE, Moore PL, Binley JM. Relationship of HIV-1 and SIV envelope glycoprotein trimer occupation and neutralization. Virology. 377: 364-78. PMID 18539308 DOI: 10.1016/J.Virol.2008.04.045  0.495
2008 Nolan KM, Jordan AP, Hoxie JA. Effects of partial deletions within the human immunodeficiency virus type 1 V3 loop on coreceptor tropism and sensitivity to entry inhibitors. Journal of Virology. 82: 664-73. PMID 17977968 DOI: 10.1128/Jvi.01793-07  0.817
2007 Laakso MM, Lee FH, Haggarty B, Agrawal C, Nolan KM, Biscone M, Romano J, Jordan AP, Leslie GJ, Meissner EG, Su L, Hoxie JA, Doms RW. V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies. Plos Pathogens. 3: e117. PMID 17722977 DOI: 10.1371/Journal.Ppat.0030117  0.833
2007 Hoxie JA, Miller V, Walker B. Tuberculosis and HIV coinfection: genesis of the supplement and sponsors' contribution. The Journal of Infectious Diseases. 196: S4. PMID 17624824 DOI: 10.1086/518666  0.426
2007 Lin G, Bertolotti-Ciarlet A, Haggarty B, Romano J, Nolan KM, Leslie GJ, Jordan AP, Huang CC, Kwong PD, Doms RW, Hoxie JA. Replication-competent variants of human immunodeficiency virus type 2 lacking the V3 loop exhibit resistance to chemokine receptor antagonists. Journal of Virology. 81: 9956-66. PMID 17609282 DOI: 10.1128/Jvi.00385-07  0.82
2007 Fernando K, Hu H, Ni H, Hoxie JA, Weissman D. Vaccine-delivered HIV envelope inhibits CD4(+) T-cell activation, a mechanism for poor HIV vaccine responses. Blood. 109: 2538-44. PMID 17158230 DOI: 10.1182/Blood-2006-08-038661  0.504
2007 Byland R, Vance PJ, Hoxie JA, Marsh M. A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein. Molecular Biology of the Cell. 18: 414-25. PMID 17108326 DOI: 10.1091/Mbc.E06-06-0535  0.502
2006 Chaipan C, Soilleux EJ, Simpson P, Hofmann H, Gramberg T, Marzi A, Geier M, Stewart EA, Eisemann J, Steinkasserer A, Suzuki-Inoue K, Fuller GL, Pearce AC, Watson SP, Hoxie JA, et al. DC-SIGN and CLEC-2 mediate human immunodeficiency virus type 1 capture by platelets. Journal of Virology. 80: 8951-60. PMID 16940507 DOI: 10.1128/Jvi.00136-06  0.535
2006 Wei Q, Stallworth JW, Vance PJ, Hoxie JA, Fultz PN. Simian immunodeficiency virus (SIV)/immunoglobulin G immune complexes in SIV-infected macaques block detection of CD16 but not cytolytic activity of natural killer cells. Clinical and Vaccine Immunology : Cvi. 13: 768-78. PMID 16829614 DOI: 10.1128/Cvi.00042-06  0.447
2005 Wyss S, Dimitrov AS, Baribaud F, Edwards TG, Blumenthal R, Hoxie JA. Regulation of human immunodeficiency virus type 1 envelope glycoprotein fusion by a membrane-interactive domain in the gp41 cytoplasmic tail. Journal of Virology. 79: 12231-41. PMID 16160149 DOI: 10.1128/Jvi.79.19.12231-12241.2005  0.52
2005 Lin G, Murphy SL, Gaulton GN, Hoxie JA. Modification of a viral envelope glycoprotein cell-cell fusion assay by utilizing plasmid encoded bacteriophage RNA polymerase. Journal of Virological Methods. 128: 135-42. PMID 15941597 DOI: 10.1016/J.Jviromet.2005.04.011  0.744
2005 Decker JM, Bibollet-Ruche F, Wei X, Wang S, Levy DN, Wang W, Delaporte E, Peeters M, Derdeyn CA, Allen S, Hunter E, Saag MS, Hoxie JA, Hahn BH, Kwong PD, et al. Antigenic conservation and immunogenicity of the HIV coreceptor binding site. The Journal of Experimental Medicine. 201: 1407-19. PMID 15867093 DOI: 10.1084/Jem.20042510  0.552
2005 Sánchez MD, Pierson TC, McAllister D, Hanna SL, Puffer BA, Valentine LE, Murtadha MM, Hoxie JA, Doms RW. Characterization of neutralizing antibodies to West Nile virus. Virology. 336: 70-82. PMID 15866072 DOI: 10.1016/J.Virol.2005.02.020  0.381
2005 Hosie MJ, Klein D, Binley JM, Dunsford TH, Jarrett O, Neil JC, Knapp E, Giannecchini S, Matteucci D, Bendinelli M, Hoxie JA, Willett BJ. Vaccination with an inactivated virulent feline immunodeficiency virus engineered to express high levels of Env. Journal of Virology. 79: 1954-7. PMID 15650222 DOI: 10.1128/Jvi.79.3.1954-1957.2005  0.37
2004 Burton DR, Desrosiers RC, Doms RW, Feinberg MB, Gallo RC, Hahn B, Hoxie JA, Hunter E, Korber B, Landay A, Lederman MM, Lieberman J, McCune JM, Moore JP, Nathanson N, et al. Public health. A sound rationale needed for phase III HIV-1 vaccine trials. Science (New York, N.Y.). 303: 316. PMID 14726576 DOI: 10.1126/Science.1094620  0.309
2003 Lin G, Hoxie JA. CCR5 mimicry by sulfated human anti-HIV-1 antibodies. Cell. 114: 147-8. PMID 12887913 DOI: 10.1016/S0092-8674(03)00564-6  0.744
2003 Lin G, Simmons G, Pöhlmann S, Baribaud F, Ni H, Leslie GJ, Haggarty BS, Bates P, Weissman D, Hoxie JA, Doms RW. Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR. Journal of Virology. 77: 1337-46. PMID 12502850 DOI: 10.1128/Jvi.77.2.1337-1346.2003  0.81
2003 Lin G, Baribaud F, Romano J, Doms RW, Hoxie JA. Identification of gp120 binding sites on CXCR4 by using CD4-independent human immunodeficiency virus type 2 Env proteins. Journal of Virology. 77: 931-42. PMID 12502809 DOI: 10.1128/Jvi.77.2.931-942.2003  0.776
2002 Chertova E, Bess JW, Crise BJ, Sowder II RC, Schaden TM, Hilburn JM, Hoxie JA, Benveniste RE, Lifson JD, Henderson LE, Arthur LO. Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU), Is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virus. Journal of Virology. 76: 5315-25. PMID 11991960 DOI: 10.1128/Jvi.76.11.5315-5325.2002  0.555
2002 Edwards TG, Wyss S, Reeves JD, Zolla-Pazner S, Hoxie JA, Doms RW, Baribaud F. Truncation of the cytoplasmic domain induces exposure of conserved regions in the ectodomain of human immunodeficiency virus type 1 envelope protein. Journal of Virology. 76: 2683-91. PMID 11861835 DOI: 10.1128/Jvi.76.6.2683-2691.2002  0.477
2002 Liu J, Wang S, Hoxie JA, LaBranche CC, Lu M. Mutations that destabilize the gp41 core are determinants for stabilizing the simian immunodeficiency virus-CPmac envelope glycoprotein complex. The Journal of Biological Chemistry. 277: 12891-900. PMID 11830586 DOI: 10.1074/Jbc.M110315200  0.44
2002 Al-Harthi L, Guilbert LJ, Hoxie JA, Landay A. Trophoblasts are productively infected by CD4-independent isolate of HIV type 1. Aids Research and Human Retroviruses. 18: 13-7. PMID 11804552 DOI: 10.1089/088922202753394673  0.543
2001 Lin G, Lee B, Haggarty BS, Doms RW, Hoxie JA. CD4-independent use of Rhesus CCR5 by human immunodeficiency virus Type 2 implicates an electrostatic interaction between the CCR5 N terminus and the gp120 C4 domain. Journal of Virology. 75: 10766-78. PMID 11602718 DOI: 10.1128/Jvi.75.22.10766-10778.2001  0.774
2001 Baribaud F, Pöhlmann S, Sparwasser T, Kimata MT, Choi YK, Haggarty BS, Ahmad N, Macfarlan T, Edwards TG, Leslie GJ, Arnason J, Reinhart TA, Kimata JT, Littman DR, Hoxie JA, et al. Functional and antigenic characterization of human, rhesus macaque, pigtailed macaque, and murine DC-SIGN. Journal of Virology. 75: 10281-9. PMID 11581396 DOI: 10.1128/Jvi.75.21.10281-10289.2001  0.758
2001 Kim M, Chen B, Hussey RE, Chishti Y, Montefiori D, Hoxie JA, Byron O, Campbell G, Harrison SC, Reinherz EL. The Stoichiometry of Trimeric SIV Glycoprotein Interaction with CD4 Differs from That of Anti-envelope Antibody Fab Fragments Journal of Biological Chemistry. 276: 42667-42676. PMID 11544255 DOI: 10.1074/Jbc.M104166200  0.481
2001 Edwards TG, Hoffman TL, Baribaud F, Wyss S, LaBranche CC, Romano J, Adkinson J, Sharron M, Hoxie JA, Doms RW. Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein. Journal of Virology. 75: 5230-9. PMID 11333905 DOI: 10.1128/Jvi.75.11.5230-5239.2001  0.487
2001 BouHamdan M, Strayer DS, Wei D, Mukhtar M, Duan LX, Hoxie J, Pomerantz RJ. Inhibition of HIV-1 infection by down-regulation of the CXCR4 co-receptor using an intracellular single chain variable fragment against CXCR4. Gene Therapy. 8: 408-18. PMID 11313818 DOI: 10.1038/sj.gt.3301411  0.487
2001 Means RE, Matthews T, Hoxie JA, Malim MH, Kodama T, Desrosiers RC. Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4. Journal of Virology. 75: 3903-15. PMID 11264379 DOI: 10.1128/Jvi.75.8.3903-3915.2001  0.458
2001 Fultz PN, Vance PJ, Endres MJ, Tao B, Dvorin JD, Davis IC, Lifson JD, Montefiori DC, Marsh M, Malim MH, Hoxie JA. In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail. Journal of Virology. 75: 278-91. PMID 11119598 DOI: 10.1128/Jvi.75.1.278-291.2001  0.436
2000 Bowers K, Pelchen-Matthews A, Höning S, Vance PJ, Creary L, Haggarty BS, Romano J, Ballensiefen W, Hoxie JA, Marsh M. The simian immunodeficiency virus envelope glycoprotein contains multiple signals that regulate its cell surface expression and endocytosis Traffic. 1: 661-674. PMID 11208154 DOI: 10.1034/J.1600-0854.2000.010810.X  0.416
2000 Edinger AL, Ahuja M, Sung T, Baxter KC, Haggarty B, Doms RW, Hoxie JA. Characterization and epitope mapping of neutralizing monoclonal antibodies produced by immunization with oligomeric simian immunodeficiency virus envelope protein Journal of Virology. 74: 7922-7935. PMID 10933700 DOI: 10.1128/Jvi.74.17.7922-7935.2000  0.493
2000 Molino M, Woolkalis MJ, Prevost N, Praticó D, Barnathan ES, Taraboletti G, Haggarty BS, Hesselgesser J, Horuk R, Hoxie JA, Brass LF. CXCR4 on human endothelial cells can serve as both a mediator of biological responses and as a receptor for HIV-2 Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1500: 227-240. PMID 10657592 DOI: 10.1016/S0925-4439(99)00110-6  0.465
1999 LaBranche CC, Hoffman TL, Romano J, Haggarty BS, Edwards TG, Matthews TJ, Doms RW, Hoxie JA. Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity. Journal of Virology. 73: 10310-9. PMID 10559349 DOI: 10.1128/Jvi.73.12.10310-10319.1999  0.577
1999 Cheng H, Hoxie J, Parks WP. The conserved core of human immunodeficiency virus type 1 Nef is essential for association with Lck and for enhanced vital replication in T- lymphocytes Virology. 264: 5-15. PMID 10544125 DOI: 10.1006/Viro.1999.9937  0.534
1999 Murakami T, Zhang TY, Koyanagi Y, Tanaka Y, Kim J, Suzuki Y, Minoguchi S, Tamamura H, Waki M, Matsumoto A, Fujii N, Shida H, Hoxie JA, Peiper SC, Yamamoto N. Inhibitory mechanism of the CXCR4 antagonist T22 against human immunodeficiency virus type 1 infection Journal of Virology. 73: 7489-7496. PMID 10438838 DOI: 10.1128/Jvi.76.2.933.2002  0.499
1999 Lallos LB, Laal S, Hoxie JA, Zolla-Pazner S, Bandres JC. Exclusion of HIV coreceptors CXCR4, CCR5, and CCR3 from the HIV envelope Aids Research and Human Retroviruses. 15: 895-897. PMID 10408726 DOI: 10.1089/088922299310601  0.584
1999 Aiuti A, Tavian M, Cipponi A, Ficara F, Zappone E, Hoxie J, Peault B, Bordignon C. Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lymphohematopoietic progenitors European Journal of Immunology. 29: 1823-1831. PMID 10382744 DOI: 10.1002/(Sici)1521-4141(199906)29:06<1823::Aid-Immu1823>3.0.Co;2-B  0.4
1999 Hoffman TL, LaBranche CC, Zhang W, Canziani G, Robinson J, Chaiken I, Hoxie JA, Doms RW. Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 6359-64. PMID 10339592 DOI: 10.1073/Pnas.96.11.6359  0.562
1999 Doranz BJ, Orsini MJ, Turner JD, Hoffman TL, Berson JF, Hoxie JA, Peiper SC, Brass LF, Doms RW. Identification of CXCR4 domains that support coreceptor and chemokine receptor functions. Journal of Virology. 73: 2752-61. PMID 10074122 DOI: 10.1128/Jvi.73.4.2752-2761.1999  0.554
1999 Kowalska MA, Ratajczak J, Hoxie J, Brass LF, Gewirtz A, Poncz M, Ratajczak MZ. Megakaryocyte precursors, megakaryocytes and platelets express the HIV co-receptor CXCR4 on their surface: Determination of response to stromal- derived factor-1 by megakaryocytes and platelets British Journal of Haematology. 104: 220-229. PMID 10050701 DOI: 10.1046/J.1365-2141.1999.01169.X  0.469
1999 Suzuki Y, Koyanagi Y, Tanaka Y, Murakami T, Misawa N, Maeda N, Kimura T, Shida H, Hoxie JA, O'Brien WA, Yamamoto N. Determinant in human immunodeficiency virus type 1 for efficient replication under cytokine-induced CD4+ T-helper 1 (Th1)- and Th2-type conditions Journal of Virology. 73: 316-324. PMID 9847335 DOI: 10.1128/Jvi.73.1.316-324.1999  0.45
1998 Hoxie JA, LaBranche CC, Endres MJ, Turner JD, Berson JF, Doms RW, Matthews TJ. CD4-independent utilization of the CXCR4 chemokine receptor by HIV-1 and HIV-2. Journal of Reproductive Immunology. 41: 197-211. PMID 10213311 DOI: 10.1016/S0165-0378(98)00059-X  0.592
1998 Chang AH, Hoxie JA, Cassol S, O'Shaughnessy M, Jirik F. Construction of single-chain antibodies that bind an overlapping epitope of HIV-1 Nef Febs Letters. 441: 307-312. PMID 9883905 DOI: 10.1016/S0014-5793(98)01569-5  0.405
1998 Zhao SF, Li W, Dornadula G, Dicker D, Hoxie J, Peiper SC, Pomerantz RJ, Duan LX. Chemokine receptors and the molecular basis for human immunodeficiency virus type 1 entry into peripheral hematopoietic stem cells and their progeny Journal of Infectious Diseases. 178: 1623-1634. PMID 9815214 DOI: 10.1086/314506  0.575
1998 Kinter A, Catanzaro A, Monaco J, Ruiz M, Justement J, Moir S, Arthos J, Oliva A, Ehler L, Mizell S, Jackson R, Ostrowski M, Hoxie J, Offord R, Fauci AS. CC-chemokines enhance the replication of T-tropic strains of HIV-1 in CD4+ T cells: Role of signal transduction Proceedings of the National Academy of Sciences of the United States of America. 95: 11880-11885. PMID 9751759 DOI: 10.1073/Pnas.95.20.11880  0.531
1998 Mondor I, Moulard M, Ugolini S, Klasse PJ, Hoxie J, Amara A, Delaunay T, Wyatt R, Sodroski J, Sattentau QJ. Interactions among HIV gp120, CD4, and CXCR4: Dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies Virology. 248: 394-405. PMID 9721247 DOI: 10.1006/Viro.1998.9282  0.517
1998 Signoret N, Rosenkilde MM, Klasse PJ, Schwartz TW, Malim MH, Hoxie JA, Marsh M. Differential regulation of CXCR4 and CCR5 endocytosis Journal of Cell Science. 111: 2819-2830. PMID 9718374  0.332
1998 Hamada T, Möhle R, Hesselgesser J, Hoxie J, Nachman RL, Moore MAS, Rafii S. Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation Journal of Experimental Medicine. 188: 539-548. PMID 9687531 DOI: 10.1084/Jem.188.3.539  0.318
1998 Willett BJ, Adema K, Heveker N, Brelot A, Picard L, Alizon M, Turner JD, Hoxie JA, Peiper S, Neil JC, Hosie MJ. The second extracellular loop of CXCR4 determines its function as a receptor for feline immunodeficiency virus. Journal of Virology. 72: 6475-81. PMID 9658090 DOI: 10.1128/Jvi.72.8.6475-6481.1998  0.533
1998 Elder JH, Dean GA, Hoover EA, Hoxie JA, Malim MH, Mathes L, Neil JC, North TW, Sparger E, Tompkins MB, Tompkins WA, Yamamoto J, Yuhki N, Pedersen NC, Miller RH. Lessons from the cat: feline immunodeficiency virus as a tool to develop intervention strategies against human immunodeficiency virus type 1. Aids Research and Human Retroviruses. 14: 797-801. PMID 9643379 DOI: 10.1089/Aid.1998.14.797  0.392
1998 Hesselgesser J, Taub D, Baskar P, Greenberg M, Hoxie J, Kolson DL, Horuk R. Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1α is mediated by the chemokine receptor CXCR4 Current Biology. 8: 595-598. PMID 9601645 DOI: 10.1016/S0960-9822(98)70230-1  0.531
1998 Mo H, Monard S, Pollack H, Ip J, Rochford G, Wu L, Hoxie J, Borkowsky W, Ho DD, Moore JP. Expression patterns of the HIV type 1 coreceptors CCR5 and CXCR4 on CD4+ T cells and monocytes from cord and adult blood. Aids Research and Human Retroviruses. 14: 607-17. PMID 9591715 DOI: 10.1089/Aid.1998.14.607  0.393
1998 Rubbert A, Combadiere C, Ostrowski M, Arthos J, Dybul M, Machado E, Cohn MA, Hoxie JA, Murphy PM, Fauci AS, Weissman D. Dendritic cells express multiple chemokine receptors used as coreceptors for HIV entry. Journal of Immunology (Baltimore, Md. : 1950). 160: 3933-41. PMID 9558100  0.425
1998 Yang LP, Riley JL, Carroll RG, June CH, Hoxie J, Patterson BK, Ohshima Y, Hodes RJ, Delespesse G. Productive infection of neonatal CD8+ T lymphocytes by HIV-1 Journal of Experimental Medicine. 187: 1139-1144. PMID 9529330 DOI: 10.1084/Jem.187.7.1139  0.532
1998 Bandres JC, Wang QF, O'Leary J, Baleaux F, Amara A, Hoxie JA, Zolla- Pazner S, Gorny MK. Human immunodeficiency virus (HIV) envelope binds to CXCR4 independently of CD4, and binding can be enhanced by interaction with soluble CD4 or by HIV envelope deglycosylation Journal of Virology. 72: 2500-2504. PMID 9499113 DOI: 10.1128/Jvi.72.3.2500-2504.1998  0.602
1998 Hosie MJ, Broere N, Hesselgesser J, Turner JD, Hoxie JA, Neil JC, Willett BJ. Modulation of feline immunodeficiency virus infection by stromal cell-derived factor. Journal of Virology. 72: 2097-104. PMID 9499065 DOI: 10.1128/Jvi.72.3.2097-2104.1998  0.397
1998 Montefiori DC, Collman RG, Fouts TR, Zhou JY, Bilska M, Hoxie JA, Moore JP, Bolognesi DP. Evidence that antibody-mediated neutralization of human immunodeficiency virus type 1 by sera from infected individuals is independent of coreceptor usage Journal of Virology. 72: 1886-1893. PMID 9499040 DOI: 10.1128/Jvi.72.3.1886-1893.1998  0.553
1998 Trkola A, Paxton WA, Monard SP, Hoxie JA, Siani MA, Thompson DA, Wu L, Mackay CR, Horuk R, Moore JP. Genetic subtype-independent inhibition of human immunodeficiency virus type 1 replication by CC and CXC chemokines Journal of Virology. 72: 396-404. PMID 9420238 DOI: 10.1128/Jvi.72.1.396-404.1998  0.462
1998 Willett BJ, Adema K, Heveker N, Brelot A, Picard L, Alizon M, Turner JD, Hoxie JA, Peiper S, Neil JC, Hosie MJ. The Second Extracellular Loop of CXCR4 Determines Its Function as a Receptor for Feline Immunodeficiency Virus Journal of Virology. 72: 8460-8460. DOI: 10.1128/jvi.72.10.8460a-8460a.1998  0.301
1997 Moriuchi H, Moriuchi M, Arthos J, Hoxie J, Fauci AS. Promonocytic U937 subclones expressing CD4 and CXCR4 are resistant to infection with and cell-to-cell fusion by T-cell-tropic human immunodeficiency virus type 1 Journal of Virology. 71: 9664-9671. PMID 9371631 DOI: 10.1128/Jvi.71.12.9664-9671.1997  0.582
1997 Endres MJ, Jaffer S, Haggarty B, Turner JD, Doranz BJ, O'Brien PJ, Kolson DL, Hoxie JA. Targeting of HIV- and SIV-infected cells by CD4-chemokine receptor pseudotypes. Science (New York, N.Y.). 278: 1462-4. PMID 9367958 DOI: 10.1126/Science.278.5342.1462  0.586
1997 Signoret N, Oldridge J, Pelchen-Matthews A, Klasse PJ, Tran T, Brass LF, Rosenkilde MM, Schwartz TW, Holmes W, Dallas W, Luther MA, Wells TN, Hoxie JA, Marsh M. Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4. The Journal of Cell Biology. 139: 651-64. PMID 9348282 DOI: 10.1083/Jcb.139.3.651  0.536
1997 Bron R, Klasse PJ, Wilkinson D, Clapham PR, Pelchen-Matthews A, Power C, Wells TNC, Kim J, Peiper SC, Hoxie JA, Marsh M. Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by a human immunodeficiency virus type 2 envelope protein Journal of Virology. 71: 8405-8415. PMID 9343197 DOI: 10.1128/Jvi.71.11.8405-8415.1997  0.549
1997 Lavi E, Strizki JM, Ulrich AM, Zhang W, Fu L, Wang Q, O'Connor M, Hoxie JA, González-Scarano F. CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons. The American Journal of Pathology. 151: 1035-42. PMID 9327737  0.436
1997 Ramachandran R, Klufas AS, Molino M, Ahuja M, Hoxie JA, Brass LF. Release of the thrombin receptor (PAR-1) N-terminus from the surface of human platelets activated by thrombin Thrombosis and Haemostasis. 78: 1119-1124. PMID 9308764 DOI: 10.1055/S-0038-1657697  0.319
1997 Ayehunie S, Garcia-Zepeda EA, Hoxie JA, Horuk R, Kupper TS, Luster AD, Ruprecht RM. Human Immunodeficiency virus-1 entry into purified blood dendritic cells through CC and CXC chemokine coreceptors Blood. 90: 1379-1386. PMID 9269754 DOI: 10.1182/Blood.V90.4.1379.1379_1379_1386  0.411
1997 D'Apuzzo M, Rolink A, Loetscher M, Hoxie JA, Clark-Lewis I, Melchers F, Baggiolini M, Moser B. The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4. European Journal of Immunology. 27: 1788-93. PMID 9247593 DOI: 10.1002/Eji.1830270729  0.302
1997 Strizki JM, Turner JD, Collman RG, Hoxie J, Gonzalez-Scarano F. A monoclonal antibody (12G5) directed against CXCR-4 inhibits infection with the dual-tropic human immunodeficiency virus type 1 isolate HIV- 189.6 but not the T-tropic isolate HIV-1(HxB) Journal of Virology. 71: 5678-5683. PMID 9188648 DOI: 10.1128/Jvi.71.7.5678-5683.1997  0.591
1997 Lu Z, Berson JF, Chen Y, Turner JD, Zhang T, Sharron M, Jenks MH, Wang Z, Kim J, Rucker J, Hoxie JA, Peiper SC, Doms RW. Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains. Proceedings of the National Academy of Sciences of the United States of America. 94: 6426-31. PMID 9177234 DOI: 10.1073/Pnas.94.12.6426  0.55
1997 Picard L, Wilkinson DA, McKnight A, Gray PW, Hoxie JA, Clapham PR, Weiss RA. Role of the amino-terminal extracellular domain of CXCR-4 in human immunodeficiency virus type 1 entry Virology. 231: 105-111. PMID 9143308 DOI: 10.1006/Viro.1997.8506  0.548
1997 Bleul CC, Wu L, Hoxie JA, Springer TA, Mackay CR. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 94: 1925-30. PMID 9050881 DOI: 10.1073/Pnas.94.5.1925  0.527
1997 Hesselgesser J, Halks-Miller M, DelVecchio V, Peiper SC, Hoxie J, Kolson DL, Taub D, Horuk R. CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons. Current Biology : Cb. 7: 112-21. PMID 9024623 DOI: 10.1016/S0960-9822(06)00055-8  0.435
1997 Molino M, Barnathan ES, Numerof R, Clark J, Dreyer M, Cumashi A, Hoxie JA, Schechter N, Woolkalis M, Brass LF. Interactions of mast cell tryptase with thrombin receptors and PAR-2 Journal of Biological Chemistry. 272: 4043-4049. PMID 9020112 DOI: 10.1074/Jbc.272.7.4043  0.326
1997 McKnight A, Wilkinson D, Simmons G, Talbot S, Picard L, Ahuja M, Marsh M, Hoxie JA, Clapham PR. Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent Journal of Virology. 71: 1692-1696. PMID 8995702 DOI: 10.1128/Jvi.71.2.1692-1696.1997  0.558
1997 Moriuchi H, Moriuchi M, Arthos J, Hoxie J, Fauci AS. Promonocytic U937 subclones expressing CD4 and CXCR4 are resistant to infection with and cell-to-cell fusion by T-cell-tropic human immunodeficiency virus type 1. Journal of Virology. 71: 9664-9671. DOI: 10.1128/jvi.71.12.9664-9671.1997  0.39
1997 Lavi E, Strizki JM, Ulrich AM, Zhane W, Fu L, Wang Q, OʼConnor M, Hoxie JA, González-Searano F. CXCR-4. a Co-Receptor for HIV-I. is Expressed in the Human Brain in a Variety of Cell Types Including Neurons and Microglia Journal of Neuropathology and Experimental Neurology. 56: 597. DOI: 10.1097/00005072-199705000-00116  0.334
1997 Marsh M, Pelchen-Matthews A, Hoxie JA. Roles for endocytosis in lentiviral replication Trends in Cell Biology. 7: 1-4. DOI: 10.1016/S0962-8924(97)20038-3  0.538
1997 Hesselgesser J, Halks-Miller M, DelVecchio V, Peiper S, Hoxie J, Kolson D, Taub D, Horuk R. CD4-independent association between HIV-1 gp120 and CXCR4: Functional chemokine receptor expression in human neurons Immunology Letters. 56: 15. DOI: 10.1016/S0165-2478(97)85058-4  0.41
1997 Bastiani L, Laal S, Hoxie JA, Bandres JC. Selective lack of incorporation of CXCR4 into HIV envelope Clinical Infectious Diseases. 25: 391.  0.5
1997 Bandres JC, Wang QF, O'Leary J, Hoxie JA, Zolla-Pazner S, Gorny M. HIV envelope deglycosylation increases binding of this molecule to CXCR4 Clinical Infectious Diseases. 25: 392.  0.463
1997 Bandres JC, Wang QF, O'Leary J, Baleaux F, Amara A, Hoxie JA, Zollapazner S, Corny M. CD4 independent binding of CXCR4 to HIV envelope: Effect of the combination with soluble CD4 Clinical Infectious Diseases. 25: 391.  0.469
1996 Endres MJ, Clapham PR, Marsh M, Ahuja M, Turner JD, McKnight A, Thomas JF, Stoebenau-Haggarty B, Choe S, Vance PJ, Wells TN, Power CA, Sutterwala SS, Doms RW, Landau NR, ... Hoxie JA, et al. CD4-independent infection by HIV-2 is mediated by fusin/CXCR4. Cell. 87: 745-56. PMID 8929542 DOI: 10.1016/S0092-8674(00)81393-8  0.581
1996 Cotropia J, Ugen KE, Kliks S, Broliden K, Broliden PA, Hoxie JA, Srikantan V, Williams WV, Weiner DB. A human monoclonal antibody to HIV-1 gp41 with neutralizing activity against diverse laboratory isolates. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 12: 221-32. PMID 8673526 DOI: 10.1097/00042560-199607000-00002  0.547
1996 Sauter MM, Pelchen-Matthews A, Bron R, Marsh M, LaBranche CC, Vance PJ, Romano J, Haggarty BS, Hart TK, Lee WMF, Hoxie JA. An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface Journal of Cell Biology. 132: 795-811. PMID 8603913 DOI: 10.1083/Jcb.132.5.795  0.453
1996 Richardson TM, Stryjewski BL, Broder CC, Hoxie JA, Mascola JR, Earl PL, Doms RW. Humoral response to oligomeric human immunodeficiency virus type 1 envelope protein Journal of Virology. 70: 753-762. PMID 8551612 DOI: 10.1128/Jvi.70.2.753-762.1996  0.505
1995 Molino M, Blanchard N, Belmonte E, Tarver AP, Abrams C, Hoxie JA, Cerletti C, Brass LF. Proteolysis of the human platelet and endothelial cell thrombin receptor by neutrophil-derived cathepsin G Journal of Biological Chemistry. 270: 11168-11175. PMID 7744748 DOI: 10.1074/Jbc.270.19.11168  0.348
1995 Woolkalis MJ, DeMelfi TM, Blanchard N, Hoxie JA, Brass LF. Regulation of thrombin receptors on human umbilical vein endothelial cells Journal of Biological Chemistry. 270: 9868-9875. PMID 7730369 DOI: 10.1074/Jbc.270.17.9868  0.318
1995 LaBranche CC, Sauter MM, Haggarty BS, Vance PJ, Romano J, Hart TK, Bugelski PJ, Marsh M, Hoxie JA. A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells Journal of Virology. 69: 5217-5227. PMID 7636963 DOI: 10.1128/Jvi.69.9.5217-5227.1995  0.448
1994 Labranche CC, Sauter MM, Haggarty BS, Vance PJ, Romano J, Hart TK, Bugelski PJ, Hoxie JA. Biological, molecular, and structural analysis of a cytopathic variant from a molecularly cloned simian immunodeficiency virus Journal of Virology. 68: 5509-5522. PMID 8057433 DOI: 10.1128/Jvi.68.11.7665-7667.1994  0.461
1994 Sperlagh M, Hoxie J, Maruyama H, Stefano K, Gonzales-Scarano F, Prewett M, Liang S, Matsushita S, Herlyn D. Polyclonal antiidiotypic antibodies mimicking gp 120 of HIV-1 Viral Immunology. 7: 61-69. PMID 7531443 DOI: 10.1089/Vim.1994.7.61  0.474
1993 Stefano KA, Collman R, Kolson D, Hoxie J, Nathanson N, Gonzalez-Scarano F. Replication of a macrophage-tropic strain of human immunodeficiency virus type 1 (HIV-1) in a hybrid cell line, CEMx174, suggests that cellular accessory molecules are required for HIV-1 entry. Journal of Virology. 67: 6707-15. PMID 8411372 DOI: 10.1128/Jvi.67.11.6707-6715.1993  0.583
1993 Brass LF, Hoxie JA, Manning DR. Signaling through G proteins and G protein-coupled receptors during platelet activation Thrombosis and Haemostasis. 70: 217-223. PMID 8236108 DOI: 10.1055/S-0038-1646194  0.305
1993 Langer DJ, Kuo A, Kariko K, Ahuja M, Klugherz BD, Ivanics KM, Hoxie JA, Williams WV, Liang BT, Cines DB. Regulation of the endothelial cell urokinase-type plasminogen activator receptor. Evidence for cyclic AMP-dependent and protein kinase C-dependent pathways. Circulation Research. 72: 330-40. PMID 7678205 DOI: 10.1161/01.Res.72.2.330  0.308
1993 Sperlagh M, Stefano K, Gonzalez-Scarano F, Liang S, Hoxie J, Maruyama H, Prewett M, Matsushita S, Herlyn D. Monoclonal anti-idiotypic antibodies that mimic the epitope on gp120 defined by anti-HIV-1 monoclonal antibody 0.5β Aids. 7: 1553-1559. PMID 7506914 DOI: 10.1097/00002030-199312000-00002  0.463
1992 Reitz MS, Guo HG, Oleske J, Hoxie J, Popovic M, Read-Connole E, Markham P, Streicher H, Gallo RC. On the historical origins of HIV-1 (MN) and (RF). Aids Research and Human Retroviruses. 8: 1539-41. PMID 1457197 DOI: 10.1089/Aid.1992.8.1539  0.473
1992 Chen S, Chrusciel RA, Nakanishi H, Raktabutr A, Johnson ME, Sato A, Weiner D, Hoxie J, Saragovi HU, Greene MI. Design and synthesis of a CD4 beta-turn mimetic that inhibits human immunodeficiency virus envelope glycoprotein gp120 binding and infection of human lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 89: 5872-6. PMID 1352879 DOI: 10.1073/Pnas.89.13.5872  0.43
1992 Gaulton GN, Brass LF, Kozbor D, Pletcher CH, Hoxie JA. Inhibition of T cell antigen receptor-dependent phosphorylation of CD4 in human immunodeficiency virus type 1 infected cells Journal of Biological Chemistry. 267: 4102-4109. PMID 1310988  0.471
1991 Inoue M, Hoxie JA, Ramana Reddy MV, Srinivasan A, Premkumar Reddy E. Mechanisms associated with the generation of biologically active human immunodeficiency virus type 1 particles from defective proviruses Proceedings of the National Academy of Sciences of the United States of America. 88: 2278-2282. PMID 2006168 DOI: 10.1073/Pnas.88.6.2278  0.513
1991 Hoxie JA. Hypothetical assignment of intrachain disulfide bonds for HIV-2 and SIV envelope glycoproteins Aids Research and Human Retroviruses. 7: 495-499. PMID 1931228 DOI: 10.1089/Aid.1991.7.495  0.471
1991 Moscinski LC, Nowell PC, Hoxie JA, Berger MS, Prystowsky MB. Surface marker analysis and karyotype distinguish acute biphenotypic leukemia from acute myelogenous leukemia expressing terminal deoxynucleotidyl transferase Cancer. 68: 2161-2168. PMID 1913454 DOI: 10.1002/1097-0142(19911115)68:10<2161::Aid-Cncr2820681013>3.0.Co;2-5  0.314
1991 Hoxie JA, Brass LF, Pletcher CH, Haggarty BS, Hahn BH. Cytopathic variants of an attenuated isolate of human immunodeficiency virus type 2 exhibit increased affinity for CD4 Journal of Virology. 65: 5096-5101. PMID 1870213 DOI: 10.1128/Jvi.65.9.5096-5101.1991  0.615
1991 Gregory T, Hoxie J, Watanabe C, Spellman M. Structure and function in recombinant HIV-1 gp120 and speculation about the disulfide bonding in the gp120 homologs of HIV-2 and SIV Advances in Experimental Medicine and Biology. 303: 1-14. PMID 1805558 DOI: 10.1007/978-1-4684-6000-1_1  0.573
1991 Hoxie JA. CD4 envelope interactions of HIV-1 and related human retroviruses Advances in Experimental Medicine and Biology. 300: 159-166. PMID 1781342 DOI: 10.1007/978-1-4684-5976-0_10  0.55
1991 Liang S, Rieber P, Prewett M, Riethmuller G, Pletcher C, Hoxie J, Koprowski H, Herlyn D. Anti-idiotypic antibodies against anti-CD4 antibodies MT151 and OKT4A Viral Immunology. 4: 83-90. PMID 1722100 DOI: 10.1089/Vim.1991.4.83  0.508
1990 Kumar P, Hui H, Kappes JC, Haggarty BS, Hoxie JA, Arya SK, Shaw GM, Hahn BH. Molecular characterization of an attenuated human immunodeficiency virus type 2 isolate Journal of Virology. 64: 890-901. PMID 2296086 DOI: 10.1128/Jvi.64.2.890-901.1990  0.518
1990 Bandyopadhyay S, Ziegner U, Campbell DE, Miller DS, Hoxie JA, Starr SE. Natural killer cell-mediated lysis of T cell lines chronically infected with HIV-1 Clinical and Experimental Immunology. 79: 430-435. PMID 1969336 DOI: 10.1111/J.1365-2249.1990.Tb08107.X  0.454
1989 Harouse JM, Kunsch C, Hartle HT, Laughlin MA, Hoxie JA, Wigdahl B, Gonzalez-Scarano F. CD4-independent infection of human neural cells by human immunodeficiency virus type 1 Journal of Virology. 63: 2527-2533. PMID 2786088 DOI: 10.1128/Jvi.63.6.2527-2533.1989  0.529
1989 Harouse JM, Laughlin M, Hoxie JA, Trojanowski JQ, Gonzalez-Scarano F. HIV infection of neural cells Annals of the New York Academy of Sciences. 567: 285-287. DOI: 10.1111/J.1749-6632.1989.Tb16482.X  0.481
1988 Kong LI, Lee SW, Kappes JC, Parkin JS, Decker D, Hoxie JA, Hahn BH, Shaw GM. West African HIV-2-related human retrovirus with attenuated cytopathicity Science. 240: 1525-1529. PMID 3375832 DOI: 10.1126/Science.3375832  0.584
1988 Hoxie JA, Rackowski JL, Haggarty BS, Gaulton GN. T4 endocytosis and phosphorylation induced by phorbol esters but not by mitogen or HIV infection Journal of Immunology. 140: 786-795. PMID 3257504  0.354
1988 Lauer SA, Fischer J, Jones J, Gartner S, Dutcher J, Hoxie JA. Orbital T-cell lymphoma in human T-cell leukemia virus-I infection Ophthalmology. 95: 110-115. PMID 2893999 DOI: 10.1016/S0161-6420(88)33231-8  0.376
1988 Hoxie JA, Haggarty BS, Bonser SE, Rackowski JL, Shan H, Kanki PJ. Biological characterization of a simian immunodeficiency virus-like retrovirus (HTLV-IV): Evidence for CD4-associated molecules required for infection Journal of Virology. 62: 2557-2568. PMID 2839686 DOI: 10.1128/Jvi.62.8.2557-2568.1988  0.581
1987 Fischkoff SA, Kishi K, Benjamin WR, Rossi RM, Hoessly MC, Hoxie JA, Seals C, Anderson L, Ishizaka T, Hakimi J. Induction of differentiation of the human leukemia cell line, KU812 Leukemia Research. 11. PMID 3695564 DOI: 10.1016/0145-2126(87)90164-0  0.312
1987 Hoxie JA. Current concepts in the virology of infection with human immunodeficiency virus (HIV): A view from the III International Conference on AIDS Annals of Internal Medicine. 107: 406-408. PMID 3650041 DOI: 10.7326/0003-4819-107-2-406  0.522
1987 Yeager BA, Hoxie J, Weisman RA, Greenberg MS, Bilaniuk LT. Cervicofacial Actinomycosis-Reply Archives of Otolaryngology--Head and Neck Surgery. 113: 777-778. PMID 3580164 DOI: 10.1001/Archotol.1987.01860070091026  0.326
1987 Hoxie JA, Fitzharris TP, Youngbar PR, Matthews DM, Rackowski JL, Radka SF. Nonrandom association of cellular antigens with HTLV-III virions Human Immunology. 18: 39-52. PMID 3542913 DOI: 10.1016/0198-8859(87)90111-X  0.347
1987 Gonzalez-Scarano F, Waxham MN, Ross AM, Hoxie JA. Sequence similarities between human immunodeficiency virus gp41 and paramyxovirus fusion proteins. Aids Research and Human Retroviruses. 3: 245-52. PMID 3501726  0.499
1986 Yeager BA, Hoxie J, Weisman RA, Greenberg MS, Bilaniuk LT. Actinomycosis in the Acquired Immunodeficiency Syndrome-Related Complex Archives of Otolaryngology--Head and Neck Surgery. 112: 1293-1295. PMID 3768157 DOI: 10.1001/Archotol.1986.03780120057011  0.332
1986 Hoxie JA, Alpers JD, Rackowski JL, Huebner K, Haggarty BS, Cedarbaum AJ, Reed JC. Alterations in T4 (CD4) protein and mRNA synthesis in cells infected with HIV Science. 234: 1123-1127. PMID 3095925 DOI: 10.1126/Science.3095925  0.48
1986 Hoxie JA, Rackowski JL, Cedarbaum AJ, Hurwitz S, Catalano PM. Relation of human T lymphotropic virus type III antibodies to T lymphocyte subset abnormalities in hemophiliac patients The American Journal of Medicine. 81: 201-207. PMID 3017105 DOI: 10.1016/0002-9343(86)90252-4  0.343
1985 Levy JA, Kaminsky LS, Morrow WJW, Steimer K, Luciw P, Dina D, Hoxie J, Oshiro L. Infection by the retrovirus associated with the acquired immunodeficiency syndrome. Clinical, biological, and molecular features Annals of Internal Medicine. 103: 694-699. PMID 2996401 DOI: 10.1016/S0022-5347(17)44958-5  0.435
1985 Hoxie JA, Haggarty BS, Rackowski JL, Pillsbury N, Levy JA. Persistent noncytopathic infection of normal human T lymphocytes with AIDS-associated retrovirus Science. 229: 1400-1402. PMID 2994222 DOI: 10.1126/Science.2994222  0.417
1985 Hahn BH, Gonda MA, Shaw GM, Popovic M, Hoxie JA, Gallo RC, Wong-Staal F. Genomic diversity of the acquired immune deficiency syndrome virus HTLV-III: Different viruses exhibit greatest divergence in their envelope genes Proceedings of the National Academy of Sciences of the United States of America. 82: 4813-4817. PMID 2991896 DOI: 10.1073/Pnas.82.14.4813  0.349
1985 Smiley ML, Hoxie JA, Friedman HM. Herpes simplex virus type 1 infection of endothelial, epithelial, and fibroblast cells induces a receptor for C3b Journal of Immunology. 134: 2673-2678. PMID 2982950  0.313
1985 Levinson AI, Hoxie JA, Kornstein MJ, Zembryki D, Matthews DM, Schreiber AD. Absence of the OKT4 epitope on blood T cells and thymus cells in a patient with thymoma, hypogammaglobulinemia, and red blood cell aplasia The Journal of Allergy and Clinical Immunology. 76: 433-439. PMID 2411777 DOI: 10.1016/0091-6749(85)90723-7  0.34
1984 Hoxie JA, Matthews DM, Cines DB. Infection of human endothelial cells by human T-cell leukemia virus type I Proceedings of the National Academy of Sciences of the United States of America. 81: 7591-7595. PMID 6095309 DOI: 10.1073/Pnas.81.23.7591  0.401
1982 Ip SH, Rittershaus CW, Struzziero CC, Hoxie JA, Hoffman RA, Healey KW, Lifter J. Evaluation of E-rosetting human lymphocytes with OKT11 and other monoclonal antibodies Blood. 60: 795-799. PMID 6980679 DOI: 10.1182/Blood.V60.3.795.Bloodjournal603795  0.321
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