Thomas M. McIntyre - Publications

Affiliations: 
University of Utah, Salt Lake City, UT 
Area:
Cell Biology, Molecular Biology, Pathology, Microbiology Biology

185 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sahai A, Bhandari R, Koupenova M, Freedman J, Godwin M, McIntyre T, Chung M, Iskandar JP, Kamran H, Aggarwal A, Kalra A, Bartholomew J, McCrae K, Elbadawi A, Svensson L, et al. SARS-CoV-2 Receptors are Expressed on Human Platelets and the Effect of Aspirin on Clinical Outcomes in COVID-19 Patients. Research Square. PMID 33398263 DOI: 10.21203/rs.3.rs-119031/v1  0.319
2020 Sumanth MS, Jacob SP, Abhilasha KV, Manne BK, Basrur V, Lehoux S, Campbell RA, Yost CC, McIntyre TM, Cummings RD, Weyrich AS, Rondina MT, Marathe GK. Different glycoforms of alpha-1-acid glycoprotein contribute to its functional alterations in platelets and neutrophils. Journal of Leukocyte Biology. PMID 33070381 DOI: 10.1002/JLB.3A0720-422R  0.363
2019 Jimenez-Pascual A, Hale JS, Kordowski A, Pugh J, Silver DJ, Bayik D, Roversi G, Alban TJ, Rao S, Chen R, McIntyre TM, Colombo G, Taraboletti G, Holmberg KO, Forsberg-Nilsson K, et al. ADAMDEC1 maintains a growth factor signaling loop in cancer stem cells. Cancer Discovery. PMID 31434712 DOI: 10.1158/2159-8290.Cd-18-1308  0.328
2019 Hills R, Ishii S, Jancar S, McIntyre T, Ninio E, O'Neill C, Oliveira Rios FJ, Travers JB, Whittaker M. Platelet-activating factor receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f55/2019.4  0.362
2019 Jimenez-Pascual A, Hale J, Bayik D, Silver D, Roversi G, Alban T, McIntyre T, Colombo G, Taraboletti G, Holmberg K, Forsberg-Nilsson K, Lathia J, Siebzehnrubl F. STEM-07. THE ATYPICAL METALLOPROTEINASE ADAMDEC1 MAINTAINS A NOVEL FGF MEDIATED SIGNALLING NETWORK IN GLIOBLASTOMA CANCER STEM CELLS Neuro-Oncology. 21: vi235-vi235. DOI: 10.1093/Neuonc/Noz175.981  0.336
2019 Jimenez-Pascual A, Hale J, Kordowski A, Pugh J, Rao S, Silver D, Alban T, Watson D, Chen R, McIntyre T, Colombo G, Taraboletti G, Holmberg K, Forsberg-Nilsson K, Lathia J, et al. The metalloproteinase ADAMDEC1 maintains a novel growth factor signalling loop in glioblastoma cancer stem cells Neuro-Oncology. 21: iv1-iv1. DOI: 10.1093/Neuonc/Noz167.003  0.324
2018 Chen R, Jin G, Li W, McIntyre TM. Epidermal Growth Factor (EGF) Autocrine Activation of Human Platelets Promotes EGF Receptor-Dependent Oral Squamous Cell Carcinoma Invasion, Migration, and Epithelial Mesenchymal Transition. Journal of Immunology (Baltimore, Md. : 1950). PMID 30150285 DOI: 10.4049/Jimmunol.1800124  0.456
2018 Chaithra VH, Jacob SP, Lakshmikanth CL, Sumanth MS, Abhilasha KV, Chen CH, Thyagarajan A, Sahu RP, Travers JB, McIntyre TM, Kemparaju K, Marathe GK. Modulation of inflammatory platelet-activating factor (PAF) receptor by the acyl analog of PAF. Journal of Lipid Research. PMID 30139761 DOI: 10.1194/jlr.M085704  0.325
2017 Chen R, Jin G, McIntyre TM. The soluble protease ADAMDEC1 released from activated platelets hydrolyzes platelet membrane pro-EGF to active high molecular weight EGF. The Journal of Biological Chemistry. PMID 28455445 DOI: 10.1074/Jbc.M116.771642  0.445
2016 Unruh D, Schwarze SR, Khoury L, Thomas C, Wu M, Chen L, Chen R, Liu Y, Schwartz MA, Amidei C, Kumthekar P, Benjamin CG, Song K, Dawson C, Rispoli JM, ... ... McIntyre T, et al. Mutant IDH1 and thrombosis in gliomas. Acta Neuropathologica. PMID 27664011 DOI: 10.1007/S00401-016-1620-7  0.301
2016 Frontera JA, Provencio JJ, Sehba FA, McIntyre TM, Nowacki AS, Gordon E, Weimer JM, Aledort L. The Role of Platelet Activation and Inflammation in Early Brain Injury Following Subarachnoid Hemorrhage. Neurocritical Care. PMID 27430874 DOI: 10.1007/S12028-016-0292-4  0.349
2016 Zhu W, Gregory JC, Org E, Buffa JA, Gupta N, Wang Z, Li L, Fu X, Wu Y, Mehrabian M, Sartor RB, McIntyre TM, Silverstein RL, Tang WH, DiDonato JA, et al. Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk. Cell. PMID 26972052 DOI: 10.1016/J.Cell.2016.02.011  0.411
2015 Marathe GK, McIntyre TM. PAF is a potent pyrogen and cryogen in rodents, but it does not mediate thermoregulatory responses to bacterial endotoxin. Temperature (Austin, Tex.). 2: 449-50. PMID 27227061 DOI: 10.1080/23328940.2015.1096439  0.365
2015 Gupta N, Li W, McIntyre TM. Deubiquitinases Modulate Platelet Proteome Ubiquitination, Aggregation, and Thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26471267 DOI: 10.1161/Atvbaha.115.306054  0.41
2014 Li W, Gigante A, Perez-Perez MJ, Yue H, Hirano M, McIntyre TM, Silverstein RL. Thymidine phosphorylase participates in platelet signaling and promotes thrombosis. Circulation Research. 115: 997-1006. PMID 25287063 DOI: 10.1161/Circresaha.115.304591  0.365
2014 Srikanthan S, Li W, Silverstein RL, McIntyre TM. Exosome poly-ubiquitin inhibits platelet activation, downregulates CD36 and inhibits pro-atherothombotic cellular functions. Journal of Thrombosis and Haemostasis : Jth. 12: 1906-17. PMID 25163645 DOI: 10.1111/Jth.12712  0.435
2014 Hale JS, Otvos B, Sinyuk M, Alvarado AG, Hitomi M, Stoltz K, Wu Q, Flavahan W, Levison B, Johansen ML, Schmitt D, Neltner JM, Huang P, Ren B, Sloan AE, ... ... McIntyre T, et al. Cancer stem cell-specific scavenger receptor 36 drives glioblastoma progression. Stem Cells (Dayton, Ohio). 32: 1746-58. PMID 24737733 DOI: 10.1002/Stem.1716  0.324
2014 Latchoumycandane C, Nagy LE, McIntyre TM. Chronic ethanol ingestion induces oxidative kidney injury through taurine-inhibitable inflammation. Free Radical Biology & Medicine. 69: 403-16. PMID 24412858 DOI: 10.1016/J.Freeradbiomed.2014.01.001  0.301
2014 Gupta N, Li W, Willard B, Silverstein RL, McIntyre TM. Proteasome proteolysis supports stimulated platelet function and thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 160-8. PMID 24177323 DOI: 10.1161/Atvbaha.113.302116  0.429
2013 Liu J, Li W, Chen R, McIntyre TM. Circulating biologically active oxidized phospholipids show on-going and increased oxidative stress in older male mice. Redox Biology. 1: 110-4. PMID 25499575 DOI: 10.1016/J.Redox.2012.11.011  0.32
2013 Li W, McIntyre TM, Silverstein RL. Ferric chloride-induced murine carotid arterial injury: A model of redox pathology. Redox Biology. 1: 50-5. PMID 25101237 DOI: 10.1016/J.Redox.2012.11.001  0.368
2013 Brown GT, Narayanan P, Li W, Silverstein RL, McIntyre TM. Lipopolysaccharide stimulates platelets through an IL-1β autocrine loop. Journal of Immunology (Baltimore, Md. : 1950). 191: 5196-203. PMID 24081990 DOI: 10.4049/Jimmunol.1300354  0.302
2013 Schmid DI, Schwertz H, Jiang H, Campbell RA, Weyrich AS, McIntyre TM, Zimmerman GA, Kraiss LW. Translational control of JunB, an AP-1 transcription factor, in activated human endothelial cells. Journal of Cellular Biochemistry. 114: 1519-28. PMID 23297064 DOI: 10.1002/Jcb.24493  0.617
2012 Latchoumycandane C, Marathe GK, Zhang R, McIntyre TM. Oxidatively truncated phospholipids are required agents of tumor necrosis factor α (TNFα)-induced apoptosis. The Journal of Biological Chemistry. 287: 17693-705. PMID 22433871 DOI: 10.1074/Jbc.M111.300012  0.343
2012 McIntyre TM. Inflammatory Cytokines and Thrombosis Blood. 120: SCI-44-SCI-44. DOI: 10.1182/blood.v120.21.sci-44.sci-44  0.361
2011 Zhou G, Marathe GK, Willard B, McIntyre TM. Intracellular erythrocyte platelet-activating factor acetylhydrolase I inactivates aspirin in blood. The Journal of Biological Chemistry. 286: 34820-9. PMID 21844189 DOI: 10.1074/Jbc.M111.267161  0.441
2011 Chen R, Brady E, McIntyre TM. Human TMEM30a promotes uptake of antitumor and bioactive choline phospholipids into mammalian cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 3215-25. PMID 21289302 DOI: 10.4049/Jimmunol.1002710  0.402
2011 Liu J, Chen R, Marathe GK, Febbraio M, Zou W, McIntyre TM. Circulating platelet-activating factor is primarily cleared by transport, not intravascular hydrolysis by lipoprotein-associated phospholipase A2/ PAF acetylhydrolase. Circulation Research. 108: 469-77. PMID 21183738 DOI: 10.1161/CIRCRESAHA.110.228742  0.32
2010 McIntyre TM, Hazen SL. Lipid oxidation and cardiovascular disease: introduction to a review series. Circulation Research. 107: 1167-9. PMID 21071714 DOI: 10.1161/Circresaha.110.224618  0.394
2010 Yang L, Latchoumycandane C, McMullen MR, Pratt BT, Zhang R, Papouchado BG, Nagy LE, Feldstein AE, McIntyre TM. Chronic alcohol exposure increases circulating bioactive oxidized phospholipids. The Journal of Biological Chemistry. 285: 22211-20. PMID 20460374 DOI: 10.1074/Jbc.M110.119982  0.307
2010 Latchoumycandane C, Yang L, Marathe G, McIntyre T. Oxidized Phospholipids have a Crucial Role in TNFα-induced Cell Death Free Radical Biology and Medicine. 49: S168. DOI: 10.1016/J.Freeradbiomed.2010.10.476  0.318
2009 Chen R, Feldstein AE, McIntyre TM. Suppression of mitochondrial function by oxidatively truncated phospholipids is reversible, aided by bid, and suppressed by Bcl-XL. The Journal of Biological Chemistry. 284: 26297-308. PMID 19654426 DOI: 10.1074/Jbc.M109.018978  0.321
2009 Foulks JM, Marathe GK, Michetti N, Stafforini DM, Zimmerman GA, McIntyre TM, Weyrich AS. PAF-acetylhydrolase expressed during megakaryocyte differentiation inactivates PAF-like lipids. Blood. 113: 6699-706. PMID 19395675 DOI: 10.1182/Blood-2008-11-186312  0.768
2009 Chen R, Chen X, Salomon RG, McIntyre TM. Platelet activation by low concentrations of intact oxidized LDL particles involves the PAF receptor. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 363-71. PMID 19112165 DOI: 10.1161/Atvbaha.108.178731  0.448
2009 McIntyre TM, Prescott SM, Stafforini DM. The emerging roles of PAF acetylhydrolase. Journal of Lipid Research. 50: S255-9. PMID 18838739 DOI: 10.1194/Jlr.R800024-Jlr200  0.383
2008 Shashkin PN, Brown GT, Ghosh A, Marathe GK, McIntyre TM. Lipopolysaccharide is a direct agonist for platelet RNA splicing. Journal of Immunology (Baltimore, Md. : 1950). 181: 3495-502. PMID 18714022  0.337
2008 Foulks JM, Weyrich AS, Zimmerman GA, McIntyre TM. A yeast PAF acetylhydrolase ortholog suppresses oxidative death. Free Radical Biology & Medicine. 45: 434-42. PMID 18489912 DOI: 10.1016/J.Freeradbiomed.2008.04.034  0.691
2008 Miyazaki Y, Bunting M, Stafforini DM, Harris ES, McIntyre TM, Prescott SM, Frutuoso VS, Amendoeira FC, de Oliveira Nascimento D, Vieira-de-Abreu A, Weyrich AS, Castro-Faria-Neto HC, Zimmerman GA. Integrin alphaDbeta2 is dynamically expressed by inflamed macrophages and alters the natural history of lethal systemic infections. Journal of Immunology (Baltimore, Md. : 1950). 180: 590-600. PMID 18097061 DOI: 10.4049/Jimmunol.180.1.590  0.342
2007 Chen J, Yang L, Foulks JM, Weyrich AS, Marathe GK, McIntyre TM. Intracellular PAF catabolism by PAF acetylhydrolase counteracts continual PAF synthesis. Journal of Lipid Research. 48: 2365-76. PMID 17693621 DOI: 10.1194/Jlr.M700325-Jlr200  0.763
2007 Chen R, Yang L, McIntyre TM. Cytotoxic phospholipid oxidation products. Cell death from mitochondrial damage and the intrinsic caspase cascade. The Journal of Biological Chemistry. 282: 24842-50. PMID 17597068 DOI: 10.1074/Jbc.M702865200  0.325
2007 Weyrich AS, Denis MM, Schwertz H, Tolley ND, Foulks J, Spencer E, Kraiss LW, Albertine KH, McIntyre TM, Zimmerman GA. mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets. Blood. 109: 1975-83. PMID 17110454 DOI: 10.1182/Blood-2006-08-042192  0.777
2007 Kriska T, Marathe GK, Schmidt JC, McIntyre TM, Girotti AW. Phospholipase action of platelet-activating factor acetylhydrolase, but not paraoxonase-1, on long fatty acyl chain phospholipid hydroperoxides. The Journal of Biological Chemistry. 282: 100-8. PMID 17090529 DOI: 10.1074/Jbc.M608135200  0.402
2006 Vasques E, Almeida AL, Noya V, D'Alegria B, Marathe G, McIntyre TM, Tibiriçá E, Bozza PT, Silva AR, Castro-Faria-Neto HC. Impairment of endothelium-dependent aorta relaxation by phospholipid components of oxidized low-density lipoprotein. Endothelium : Journal of Endothelial Cell Research. 13: 1-8. PMID 16885061 DOI: 10.1080/10623320600659948  0.352
2006 Shashkin PN, Jain N, Miller YI, Rissing BA, Huo Y, Keller SR, Vandenhoff GE, Nadler JL, McIntyre TM. Insulin and glucose play a role in foam cell formation and function. Cardiovascular Diabetology. 5: 13. PMID 16787541 DOI: 10.1186/1475-2840-5-13  0.316
2006 Stafforini DM, Sheller JR, Blackwell TS, Sapirstein A, Yull FE, McIntyre TM, Bonventre JV, Prescott SM, Roberts LJ. Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases. The Journal of Biological Chemistry. 281: 4616-23. PMID 16371369 DOI: 10.1074/Jbc.M507340200  0.339
2005 Marathe GK, Johnson C, Billings SD, Southall MD, Pei Y, Spandau D, Murphy RC, Zimmerman GA, McIntyre TM, Travers JB. Ultraviolet B radiation generates platelet-activating factor-like phospholipids underlying cutaneous damage. The Journal of Biological Chemistry. 280: 35448-57. PMID 16115894 DOI: 10.1074/Jbc.M503811200  0.431
2005 Denis MM, Tolley ND, Bunting M, Schwertz H, Jiang H, Lindemann S, Yost CC, Rubner FJ, Albertine KH, Swoboda KJ, Fratto CM, Tolley E, Kraiss LW, McIntyre TM, Zimmerman GA, et al. Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets. Cell. 122: 379-91. PMID 16096058 DOI: 10.1016/J.Cell.2005.06.015  0.789
2005 Weyrich AS, Denis MM, Kuhlmann-Eyre JR, Spencer ED, Dixon DA, Marathe GK, McIntyre TM, Zimmerman GA, Prescott SM. Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates. Circulation. 111: 633-42. PMID 15668340 DOI: 10.1161/01.Cir.0000154607.90506.45  0.796
2004 Jiang H, Weyrich AS, Zimmerman GA, McIntyre TM. Endothelial cell confluence regulates cyclooxygenase-2 and prostaglandin E2 production that modulate motility. The Journal of Biological Chemistry. 279: 55905-13. PMID 15485847 DOI: 10.1074/Jbc.M406094200  0.602
2004 Yost CC, Denis MM, Lindemann S, Rubner FJ, Marathe GK, Buerke M, McIntyre TM, Weyrich AS, Zimmerman GA. Activated polymorphonuclear leukocytes rapidly synthesize retinoic acid receptor-alpha: a mechanism for translational control of transcriptional events. The Journal of Experimental Medicine. 200: 671-80. PMID 15337793 DOI: 10.1084/Jem.20040224  0.786
2004 Zimmerman GA, McIntyre TM. PAF, ceramide and pulmonary edema: alveolar flooding and a flood of questions. Trends in Molecular Medicine. 10: 245-8. PMID 15177186 DOI: 10.1016/J.Molmed.2004.03.009  0.341
2004 Lindemann SW, Yost CC, Denis MM, McIntyre TM, Weyrich AS, Zimmerman GA. Neutrophils alter the inflammatory milieu by signal-dependent translation of constitutive messenger RNAs. Proceedings of the National Academy of Sciences of the United States of America. 101: 7076-81. PMID 15118085 DOI: 10.1073/Pnas.0401901101  0.792
2004 Dai Q, Liu J, Chen J, Durrant D, McIntyre TM, Lee RM. Mitochondrial ceramide increases in UV-irradiated HeLa cells and is mainly derived from hydrolysis of sphingomyelin. Oncogene. 23: 3650-8. PMID 15077187 DOI: 10.1038/Sj.Onc.1207430  0.307
2004 Zhang C, Baker DL, Yasuda S, Makarova N, Balazs L, Johnson LR, Marathe GK, McIntyre TM, Xu Y, Prestwich GD, Byun HS, Bittman R, Tigyi G. Lysophosphatidic acid induces neointima formation through PPARgamma activation. The Journal of Experimental Medicine. 199: 763-74. PMID 15007093 DOI: 10.1084/Jem.20031619  0.428
2004 Xu Y, Qian L, Pontsler AV, McIntyre TM, Prestwich GD. Synthesis of difluoromethyl substituted lysophosphatidic acid analogues Tetrahedron. 60: 43-49. DOI: 10.1016/J.Tet.2003.11.001  0.339
2003 Stafforini DM, McIntyre TM, Zimmerman GA, Prescott SM. Platelet-activating factor, a pleiotrophic mediator of physiological and pathological processes. Critical Reviews in Clinical Laboratory Sciences. 40: 643-72. PMID 14708958 DOI: 10.1080/714037693  0.437
2003 Qian L, Xu Y, Arai H, Aoki J, McIntyre TM, Prestwich GD. Synthesis of migration-resistant hydroxyethoxy analogues of lysophosphatidic acid. Organic Letters. 5: 4685-8. PMID 14627415 DOI: 10.1021/Ol0358758  0.335
2003 Watanabe J, Miyazaki Y, Zimmerman GA, Albertine KH, McIntyre TM. Endotoxin contamination of ovalbumin suppresses murine immunologic responses and development of airway hyper-reactivity. The Journal of Biological Chemistry. 278: 42361-8. PMID 12909619 DOI: 10.1074/Jbc.M307752200  0.475
2003 de Assis EF, Silva AR, Caiado LF, Marathe GK, Zimmerman GA, Prescott SM, McIntyre TM, Bozza PT, de Castro-Faria-Neto HC. Synergism between platelet-activating factor-like phospholipids and peroxisome proliferator-activated receptor gamma agonists generated during low density lipoprotein oxidation that induces lipid body formation in leukocytes. Journal of Immunology (Baltimore, Md. : 1950). 171: 2090-8. PMID 12902515 DOI: 10.4049/Jimmunol.171.4.2090  0.377
2003 Wu X, McIntyre TM, Zimmerman GA, Prescott SM, Stafforini DM. Molecular characterization of the constitutive expression of the plasma platelet-activating factor acetylhydrolase gene in macrophages. The Biochemical Journal. 375: 351-63. PMID 12854969 DOI: 10.1042/Bj20030636  0.392
2003 Watanabe J, Marathe GK, Neilsen PO, Weyrich AS, Harrison KA, Murphy RC, Zimmerman GA, McIntyre TM. Endotoxins stimulate neutrophil adhesion followed by synthesis and release of platelet-activating factor in microparticles. The Journal of Biological Chemistry. 278: 33161-8. PMID 12810708 DOI: 10.1074/Jbc.M305321200  0.59
2003 Grissom CK, Orme JF, Richer LD, McIntyre TM, Zimmerman GA, Elstad MR. Platelet-activating factor acetylhydrolase is increased in lung lavage fluid from patients with acute respiratory distress syndrome. Critical Care Medicine. 31: 770-5. PMID 12626982 DOI: 10.1097/01.Ccm.0000053647.82608.29  0.35
2003 McIntyre TM, Prescott SM, Weyrich AS, Zimmerman GA. Cell-cell interactions: leukocyte-endothelial interactions. Current Opinion in Hematology. 10: 150-8. PMID 12579042 DOI: 10.1097/00062752-200303000-00009  0.361
2003 Kraiss LW, Alto NM, Dixon DA, McIntyre TM, Weyrich AS, Zimmerman GA. Fluid flow regulates E-selectin protein levels in human endothelial cells by inhibiting translation. Journal of Vascular Surgery. 37: 161-8. PMID 12514595 DOI: 10.1067/Mva.2003.67  0.319
2003 McIntyre TM, Pontsler AV, Silva AR, St Hilaire A, Xu Y, Hinshaw JC, Zimmerman GA, Hama K, Aoki J, Arai H, Prestwich GD. Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist. Proceedings of the National Academy of Sciences of the United States of America. 100: 131-6. PMID 12502787 DOI: 10.1073/Pnas.0135855100  0.444
2003 Marathe GK, Zimmerman GA, McIntyre TM. Platelet-activating factor acetylhydrolase, and not paraoxonase-1, is the oxidized phospholipid hydrolase of high density lipoprotein particles. The Journal of Biological Chemistry. 278: 3937-47. PMID 12466264 DOI: 10.1074/Jbc.M211126200  0.397
2002 Marathe GK, Zimmerman GA, Prescott SM, McIntyre TM. Activation of vascular cells by PAF-like lipids in oxidized LDL. Vascular Pharmacology. 38: 193-200. PMID 12449015 DOI: 10.1016/S1537-1891(02)00169-6  0.436
2002 Galt SW, Lindemann S, Allen L, Medd DJ, Falk JM, McIntyre TM, Prescott SM, Kraiss LW, Zimmerman GA, Weyrich AS. Outside-in signals delivered by matrix metalloproteinase-1 regulate platelet function. Circulation Research. 90: 1093-9. PMID 12039799 DOI: 10.1161/01.Res.0000019241.12929.Eb  0.39
2002 Prescott SM, McIntyre TM, Zimmerman GA, Stafforini DM. Sol Sherry lecture in thrombosis: molecular events in acute inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 727-33. PMID 12006383 DOI: 10.1161/01.Atv.0000016153.47693.B2  0.478
2002 Zimmerman GA, McIntyre TM, Prescott SM, Stafforini DM. The platelet-activating factor signaling system and its regulators in syndromes of inflammation and thrombosis. Critical Care Medicine. 30: S294-301. PMID 12004251 DOI: 10.1097/00003246-200205001-00020  0.439
2002 Silva AR, de Assis EF, Caiado LF, Marathe GK, Bozza MT, McIntyre TM, Zimmerman GA, Prescott SM, Bozza PT, Castro-Faria-Neto HC. Monocyte chemoattractant protein-1 and 5-lipoxygenase products recruit leukocytes in response to platelet-activating factor-like lipids in oxidized low-density lipoprotein. Journal of Immunology (Baltimore, Md. : 1950). 168: 4112-20. PMID 11937571  0.342
2002 Imaizumi T, Aratani S, Nakajima T, Carlson M, Matsumiya T, Tanji K, Ookawa K, Yoshida H, Tsuchida S, McIntyre TM, Prescott SM, Zimmerman GA, Satoh K. Retinoic acid-inducible gene-I is induced in endothelial cells by LPS and regulates expression of COX-2. Biochemical and Biophysical Research Communications. 292: 274-9. PMID 11890704 DOI: 10.1006/Bbrc.2002.6650  0.392
2002 Pontsler AV, St Hilaire A, Marathe GK, Zimmerman GA, McIntyre TM. Cyclooxygenase-2 is induced in monocytes by peroxisome proliferator activated receptor gamma and oxidized alkyl phospholipids from oxidized low density lipoprotein. The Journal of Biological Chemistry. 277: 13029-36. PMID 11809750 DOI: 10.1074/Jbc.M109546200  0.367
2002 Bunting M, Harris ES, McIntyre TM, Prescott SM, Zimmerman GA. Leukocyte adhesion deficiency syndromes: adhesion and tethering defects involving beta 2 integrins and selectin ligands. Current Opinion in Hematology. 9: 30-5. PMID 11753075 DOI: 10.1097/00062752-200201000-00006  0.305
2002 Feldhaus MJ, Weyrich AS, Zimmerman GA, McIntyre TM. Ceramide generation in situ alters leukocyte cytoskeletal organization and beta 2-integrin function and causes complete degranulation. The Journal of Biological Chemistry. 277: 4285-93. PMID 11706024 DOI: 10.1074/Jbc.M106653200  0.377
2001 Marathe GK, Prescott SM, Zimmerman GA, McIntyre TM. Oxidized LDL contains inflammatory PAF-like phospholipids. Trends in Cardiovascular Medicine. 11: 139-42. PMID 11686003 DOI: 10.1016/S1050-1738(01)00100-1  0.399
2001 Pearman AT, Castro-Faria-Neto HC, McIntyre TM, Prescott SM, Stafforini DM. Characterization of human UMP-CMP kinase enzymatic activity and 5′ untranslated region Life Sciences. 69: 2361-2370. PMID 11681623 DOI: 10.1016/S0024-3205(01)01322-4  0.35
2001 Neilsen PO, Zimmerman GA, McIntyre TM. Escherichia coli Braun lipoprotein induces a lipopolysaccharide-like endotoxic response from primary human endothelial cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 5231-9. PMID 11673537 DOI: 10.4049/Jimmunol.167.9.5231  0.403
2001 Galt SW, Lindemann S, Medd D, Allen LL, Kraiss LW, Harris ES, Prescott SM, McIntyre TM, Weyrich AS, Zimmerman GA. Differential regulation of matrix metalloproteinase-9 by monocytes adherent to collagen and platelets. Circulation Research. 89: 509-16. PMID 11557738 DOI: 10.1161/Hh1801.096339  0.406
2001 Mahoney TS, Weyrich AS, Dixon DA, McIntyre T, Prescott SM, Zimmerman GA. Cell adhesion regulates gene expression at translational checkpoints in human myeloid leukocytes. Proceedings of the National Academy of Sciences of the United States of America. 98: 10284-9. PMID 11517314 DOI: 10.1073/Pnas.181201398  0.475
2001 Lindemann S, Tolley ND, Dixon DA, McIntyre TM, Prescott SM, Zimmerman GA, Weyrich AS. Activated platelets mediate inflammatory signaling by regulated interleukin 1beta synthesis. The Journal of Cell Biology. 154: 485-90. PMID 11489912 DOI: 10.1083/Jcb.200105058  0.406
2001 Davies SS, Pontsler AV, Marathe GK, Harrison KA, Murphy RC, Hinshaw JC, Prestwich GD, Hilaire AS, Prescott SM, Zimmerman GA, McIntyre TM. Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists. The Journal of Biological Chemistry. 276: 16015-23. PMID 11279149 DOI: 10.1074/Jbc.M100878200  0.353
2001 Prescott SM, McIntyre TM, Zimmerman GA. Events at the vascular wall: the molecular basis of inflammation. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 49: 104-11. PMID 11217139 DOI: 10.2310/6650.2001.34106  0.425
2001 Harris ES, Shigeoka AO, Li W, Adams RH, Prescott SM, McIntyre TM, Zimmerman GA, Lorant DE. A novel syndrome of variant leukocyte adhesion deficiency involving defects in adhesion mediated by beta1 and beta2 integrins. Blood. 97: 767-76. PMID 11157496 DOI: 10.1182/Blood.V97.3.767  0.34
2000 Cao Y, Pearman AT, Zimmerman GA, McIntyre TM, Prescott SM. Intracellular unesterified arachidonic acid signals apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 97: 11280-5. PMID 11005842 DOI: 10.1073/Pnas.200367597  0.328
2000 Prescott SM, Zimmerman GA, Stafforini DM, McIntyre TM. Platelet-activating factor and related lipid mediators. Annual Review of Biochemistry. 69: 419-45. PMID 10966465 DOI: 10.1146/Annurev.Biochem.69.1.419  0.46
2000 Marathe GK, Harrison KA, Murphy RC, Prescott SM, Zimmerman GA, McIntyre TM. Bioactive phospholipid oxidation products. Free Radical Biology & Medicine. 28: 1762-70. PMID 10946218 DOI: 10.1016/S0891-5849(00)00234-3  0.341
2000 Maloney CG, Thompson SD, Hill HR, Bohnsack JF, McIntyre TM, Zimmerman GA. Induction of cyclooxygenase-2 by human monocytes exposed to group B streptococci. Journal of Leukocyte Biology. 67: 615-21. PMID 10811000 DOI: 10.1002/Jlb.67.5.615  0.364
2000 Harris ES, McIntyre TM, Prescott SM, Zimmerman GA. The leukocyte integrins. The Journal of Biological Chemistry. 275: 23409-12. PMID 10801898 DOI: 10.1074/Jbc.R000004200  0.34
2000 Kraiss LW, Weyrich AS, Alto NM, Dixon DA, Ennis TM, Modur V, McIntyre TM, Prescott SM, Zimmerman GA. Fluid flow activates a regulator of translation, p70/p85 S6 kinase, in human endothelial cells. American Journal of Physiology. Heart and Circulatory Physiology. 278: H1537-44. PMID 10775131 DOI: 10.1152/Ajpheart.2000.278.5.H1537  0.387
2000 Dixon DA, Kaplan CD, McIntyre TM, Zimmerman GA, Prescott SM. Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3'-untranslated region. The Journal of Biological Chemistry. 275: 11750-7. PMID 10766797 DOI: 10.1074/Jbc.275.16.11750  0.382
2000 Cao Y, Murphy KJ, McIntyre TM, Zimmerman GA, Prescott SM. Expression of fatty acid-CoA ligase 4 during development and in brain. Febs Letters. 467: 263-7. PMID 10675551 DOI: 10.1016/S0014-5793(00)01159-5  0.301
1999 Prescott SM, McIntyre TM, Zimmerman G. Two of the usual suspects, platelet-activating factor and its receptor, implicated in acute lung injury Journal of Clinical Investigation. 104: 1019-1020. PMID 10525039 DOI: 10.1172/Jci8506  0.433
1999 Marathe GK, Davies SS, Harrison KA, Silva AR, Murphy RC, Castro-Faria-Neto H, Prescott SM, Zimmerman GA, McIntyre TM. Inflammatory platelet-activating factor-like phospholipids in oxidized low density lipoproteins are fragmented alkyl phosphatidylcholines. The Journal of Biological Chemistry. 274: 28395-404. PMID 10497200 DOI: 10.1074/Jbc.274.40.28395  0.395
1999 McIntyre TM, Zimmerman GA, Prescott SM. Biologically active oxidized phospholipids. The Journal of Biological Chemistry. 274: 25189-92. PMID 10464236 DOI: 10.1074/Jbc.274.36.25189  0.306
1999 Zimmerman GA, Albertine KH, Carveth HJ, Gill EA, Grissom CK, Hoidal JR, Imaizumi T, Maloney CG, McIntyre TM, Michael JR, Orme JF, Prescott SM, Topham MS. Endothelial activation in ARDS. Chest. 116: 18S-24S. PMID 10424566 DOI: 10.1378/Chest.116.Suppl_1.18S  0.341
1999 Stafforini DM, Numao T, Tsodikov A, Vaitkus D, Fukuda T, Watanabe N, Fueki N, McIntyre TM, Zimmerman GA, Makino S, Prescott SM. Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma. The Journal of Clinical Investigation. 103: 989-97. PMID 10194471 DOI: 10.1172/Jci5574  0.303
1999 Meade EA, McIntyre TM, Zimmerman GA, Prescott SM. Peroxisome proliferators enhance cyclooxygenase-2 expression in epithelial cells. The Journal of Biological Chemistry. 274: 8328-34. PMID 10075740 DOI: 10.1074/Jbc.274.12.8328  0.389
1999 Stafforini DM, Tjoelker LW, McCormick SPA, Vaitkus D, McIntyre TM, Gray PW, Young SG, Prescott SM. Molecular basis of the interaction between plasma platelet-activating factor acetylhydrolase and low density lipoprotein Journal of Biological Chemistry. 274: 7018-7024. PMID 10066756 DOI: 10.1074/Jbc.274.11.7018  0.373
1999 Pabla R, Weyrich AS, Dixon DA, Bray PF, McIntyre TM, Prescott SM, Zimmerman GA. Integrin-dependent control of translation: engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human platelets. The Journal of Cell Biology. 144: 175-84. PMID 9885253 DOI: 10.1083/Jcb.144.1.175  0.52
1998 Ding L, Traer E, McIntyre TM, Zimmerman GA, Prescott SM. The cloning and characterization of a novel human diacylglycerol kinase, DGKiota. The Journal of Biological Chemistry. 273: 32746-52. PMID 9830018 DOI: 10.1074/Jbc.273.49.32746  0.314
1998 Topham MK, Bunting M, Zimmerman GA, McIntyre TM, Blackshear PJ, Prescott SM. Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta. Nature. 394: 697-700. PMID 9716136 DOI: 10.1038/29337  0.305
1998 Topham MK, Carveth HJ, McIntyre TM, Prescott SM, Zimmerman GA. Human endothelial cells regulate polymorphonuclear leukocyte degranulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 733-46. PMID 9619452 DOI: 10.1096/Fasebj.12.9.733  0.446
1998 Gill EA, Imaizumi T, Carveth H, Topham MK, Tarbet EB, McIntyre TM, Prescott SM, Zimmerman GA. Bacterial lipopolysaccharide induces endothelial cells to synthesize a degranulating factor for neutrophils. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 673-84. PMID 9619446 DOI: 10.1096/Fasebj.12.9.673  0.431
1998 Kessel JM, Hayflick J, Weyrich AS, Hoffman PA, Gallatin M, McIntyre TM, Prescott SM, Zimmerman GA. Coengagement of ICAM-3 and Fc receptors induces chemokine secretion and spreading by myeloid leukocytes. Journal of Immunology (Baltimore, Md. : 1950). 160: 5579-87. PMID 9605163  0.33
1998 Weyrich AS, Dixon DA, Pabla R, Elstad MR, McIntyre TM, Prescott SM, Zimmerman GA. Signal-dependent translation of a regulatory protein, Bcl-3, in activated human platelets. Proceedings of the National Academy of Sciences of the United States of America. 95: 5556-61. PMID 9576921 DOI: 10.1073/Pnas.95.10.5556  0.497
1998 Cao Y, Stafforini DM, Zimmerman GA, McIntyre TM, Prescott SM. Expression of plasma platelet-activating factor acetylhydrolase is transcriptionally regulated by mediators of inflammation. The Journal of Biological Chemistry. 273: 4012-20. PMID 9461591 DOI: 10.1074/Jbc.273.7.4012  0.477
1997 Modur V, Li Y, Zimmerman GA, Prescott SM, McIntyre TM. Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha. The Journal of Clinical Investigation. 100: 2752-6. PMID 9389739 DOI: 10.1172/Jci119821  0.348
1997 Imaizumi T, Albertine KH, Jicha DL, McIntyre TM, Prescott SM, Zimmerman GA. Human endothelial cells synthesize ENA-78: relationship to IL-8 and to signaling of PMN adhesion. American Journal of Respiratory Cell and Molecular Biology. 17: 181-92. PMID 9271306 DOI: 10.1165/Ajrcmb.17.2.2818  0.406
1997 Bunting M, Lorant DE, Bryant AE, Zimmerman GA, McIntyre TM, Stevens DL, Prescott SM. Alpha toxin from Clostridium perfringens induces proinflammatory changes in endothelial cells. The Journal of Clinical Investigation. 100: 565-74. PMID 9239403 DOI: 10.1172/Jci119566  0.392
1997 Stafforini DM, McIntyre TM, Zimmerman GA, Prescott SM. Platelet-activating factor acetylhydrolases. The Journal of Biological Chemistry. 272: 17895-8. PMID 9218411 DOI: 10.1074/Jbc.272.29.17895  0.436
1997 Modur V, Feldhaus MJ, Weyrich AS, Jicha DL, Prescott SM, Zimmerman GA, McIntyre TM. Oncostatin M is a proinflammatory mediator. In vivo effects correlate with endothelial cell expression of inflammatory cytokines and adhesion molecules. The Journal of Clinical Investigation. 100: 158-68. PMID 9202068 DOI: 10.1172/Jci119508  0.381
1997 Ding L, Bunting M, Topham MK, McIntyre TM, Zimmerman GA, Prescott SM. Alternative splicing of the human diacylglycerol kinase zeta gene in muscle. Proceedings of the National Academy of Sciences of the United States of America. 94: 5519-24. PMID 9159104 DOI: 10.1073/Pnas.94.11.5519  0.309
1997 Lehr HA, Weyrich AS, Saetzler RK, Jurek A, Arfors KE, Zimmerman GA, Prescott SM, McIntyre TM. Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. The Journal of Clinical Investigation. 99: 2358-64. PMID 9153277 DOI: 10.1172/Jci119417  0.399
1997 MacRitchie AN, Qu K, Stafforini DM, McIntyre TM, Zimmerman GA, Prescott SM. Inhibition of Platelet-activating Factor Acetylhydrolase Activity by Oxidants. † 1541 Pediatric Research. 41: 259-259. DOI: 10.1203/00006450-199704001-01560  0.445
1997 Kessel JM, Weyrich A, Hayflick J, Hoffman P, Gallatin M, McIntyre T, Prescott S, Zimmerman G. Engagement of Intercellular Adhesion Molecule 3 (ICAM-3) Induces Proinflammatory Chemokine Secretion by Myeloid Leukocytes |[bull]| 1284 Pediatric Research. 41: 216-216. DOI: 10.1203/00006450-199704001-01303  0.394
1996 Tjoelker LW, Eberhardt C, Wilder C, Dietsch G, Trong HL, Cousens LS, Zimmerman GA, McIntyre TM, Stafforini DM, Prescott SM, Gray PW. Functional and structural features of plasma platelet-activating factor acetylhydrolase. Advances in Experimental Medicine and Biology. 416: 107-11. PMID 9131135 DOI: 10.1007/978-1-4899-0179-8_19  0.467
1996 Zimmerman GA, McIntyre TM, Prescott SM. Adhesion and signaling in vascular cell--cell interactions. The Journal of Clinical Investigation. 98: 1699-702. PMID 8878418 DOI: 10.1172/Jci118967  0.323
1996 Prescott SM, McIntyre TM, Zimmerman GA, Stafforini DM. Inflammation as an early component of atherosclerosis and vascular damage--a role for P-selectin and platelet-activating factor. Japanese Circulation Journal. 60: 137-41. PMID 8741238 DOI: 10.1253/Jcj.60.137  0.414
1996 Stafforini DM, Satoh K, Atkinson DL, Tjoelker LW, Eberhardt C, Yoshida H, Imaizumi T, Takamatsu S, Zimmerman GA, McIntyre TM, Gray PW, Prescott SM. Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase. The Journal of Clinical Investigation. 97: 2784-91. PMID 8675689 DOI: 10.1172/Jci118733  0.349
1996 Stafforini DM, Prescott SM, Zimmerman GA, McIntyre TM. Mammalian platelet-activating factor acetylhydrolases. Biochimica Et Biophysica Acta. 1301: 161-73. PMID 8664325 DOI: 10.1016/0005-2760(96)00040-9  0.442
1996 Modur V, Zimmerman GA, Prescott SM, McIntyre TM. Endothelial cell inflammatory responses to tumor necrosis factor alpha. Ceramide-dependent and -independent mitogen-activated protein kinase cascades. The Journal of Biological Chemistry. 271: 13094-102. PMID 8662702 DOI: 10.1074/Jbc.271.22.13094  0.419
1996 Zimmerman GA, McIntyre TM, Prescott SM, Stafforini DM. Platelet-activating factor: antagonists, terminators, molecular mimics, and microbial opportunism. Journal of Internal Medicine. 239: 463-6. PMID 8656138 DOI: 10.1046/J.1365-2796.1996.496832000.X  0.423
1996 Weyrich AS, Elstad MR, McEver RP, McIntyre TM, Moore KL, Morrissey JH, Prescott SM, Zimmerman GA. Activated platelets signal chemokine synthesis by human monocytes. The Journal of Clinical Investigation. 97: 1525-34. PMID 8617886 DOI: 10.1172/Jci118575  0.515
1996 Pearce MJ, McIntyre TM, Prescott SM, Zimmerman GA, Whatley RE. Shear stress activates cytosolic phospholipase A2 (cPLA2) and MAP kinase in human endothelial cells. Biochemical and Biophysical Research Communications. 218: 500-4. PMID 8561785 DOI: 10.1006/Bbrc.1996.0089  0.376
1996 Tang W, Bunting M, Zimmerman GA, McIntyre TM, Prescott SM. Molecular cloning of a novel human diacylglycerol kinase highly selective for arachidonate-containing substrates Faseb Journal. 10. DOI: 10.1074/Jbc.271.17.10237  0.359
1996 Bunting M, Tang W, Zimmerman GA, McIntyre TM, Prescott SM. Molecular Cloning and Characterization of a Novel Human Diacylglycerol Kinase Journal of Biological Chemistry. 271: 10230-10236. DOI: 10.1074/Jbc.271.17.10230  0.386
1996 Imaizumi Ta, Yamada Y, Zimmerman GA, McIntyre TM, Stafforini DM, Prescott SM. The fate of platelet-activating factor. PAF acetylhydrolases from plasma and tissues Advances in Lipobiology. 1: 141-162. DOI: 10.1016/S1874-5245(96)80007-3  0.4
1995 Elstad MR, McIntyre TM, Prescott SM, Zimmerman GA. The interaction of leukocytes with platelets in blood coagulation. Current Opinion in Hematology. 2: 47-54. PMID 9371971 DOI: 10.1097/00062752-199502010-00007  0.472
1995 Lorant DE, Zimmerman GA, McIntyre TM, Prescott SM. Platelet-activating factor mediates procoagulant activity on the surface of endothelial cells by promoting leukocyte adhesion. Seminars in Cell Biology. 6: 295-303. PMID 8562922 DOI: 10.1006/Scel.1995.0039  0.481
1995 Zimmerman GA, Prescott SM, McIntyre TM. Oxidatively fragmented phospholipids as inflammatory mediators: the dark side of polyunsaturated lipids. The Journal of Nutrition. 125: 1661S-1665S. PMID 7782922 DOI: 10.1093/Jn/125.Suppl_6.1661S  0.363
1995 Imaizumi TA, Stafforini DM, Yamada Y, McIntyre TM, Prescott SM, Zimmerman GA. Platelet-activating factor: a mediator for clinicians. Journal of Internal Medicine. 238: 5-20. PMID 7608647 DOI: 10.1111/J.1365-2796.1995.Tb00894.X  0.458
1995 Heery JM, Kozak M, Stafforini DM, Jones DA, Zimmerman GA, McIntyre TM, Prescott SM. Oxidatively modified LDL contains phospholipids with platelet-activating factor-like activity and stimulates the growth of smooth muscle cells. The Journal of Clinical Investigation. 96: 2322-30. PMID 7593619 DOI: 10.1172/Jci118288  0.4
1995 Tjoelker LW, Eberhardt C, Unger J, Trong HL, Zimmerman GA, McIntyre TM, Stafforini DM, Prescott SM, Gray PW. Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad. The Journal of Biological Chemistry. 270: 25481-7. PMID 7592717 DOI: 10.1074/Jbc.270.43.25481  0.383
1995 Kimura H, Wu NZ, Dodge R, Spencer DP, Klitzman BM, McIntyre TM, Dewhirst MW. Inhibition of radiation-induced up-regulation of leukocyte adhesion to endothelial cells with the platelet-activating factor inhibitor, BN52021 International Journal of Radiation Oncology, Biology, Physics. 33: 627-633. PMID 7558952 DOI: 10.1016/0360-3016(95)00205-D  0.412
1995 Elstad MR, La Pine TR, Cowley FS, McEver RP, McIntyre TM, Prescott SM, Zimmerman GA. P-selectin regulates platelet-activating factor synthesis and phagocytosis by monocytes. Journal of Immunology (Baltimore, Md. : 1950). 155: 2109-22. PMID 7543539  0.35
1995 Lorant DE, McEver RP, McIntyre TM, Moore KL, Prescott SM, Zimmerman GA. Activation of polymorphonuclear leukocytes reduces their adhesion to P-selectin and causes redistribution of ligands for P-selectin on their surfaces. The Journal of Clinical Investigation. 96: 171-82. PMID 7542276 DOI: 10.1172/Jci118018  0.337
1994 Whatley RE, Satoh K, Zimmerman GA, McIntyre TM, Prescott SM. Proliferation-dependent changes in release of arachidonic acid from endothelial cells. The Journal of Clinical Investigation. 94: 1889-900. PMID 7962534 DOI: 10.1172/Jci117539  0.323
1994 Yamada Y, Stafforini DM, Imaizumi T, Zimmerman GA, McIntyre TM, Prescott SM. Characterization of the platelet-activating factor acetylhydrolase from human plasma by heterologous expression in Xenopus laevis oocytes. Proceedings of the National Academy of Sciences of the United States of America. 91: 10320-4. PMID 7937948 DOI: 10.1073/Pnas.91.22.10320  0.435
1994 Patel KD, Modur V, Zimmerman GA, Prescott SM, McIntyre TM. The necrotic venom of the brown recluse spider induces dysregulated endothelial cell-dependent neutrophil activation. Differential induction of GM-CSF, IL-8, and E-selectin expression. The Journal of Clinical Investigation. 94: 631-42. PMID 7518841 DOI: 10.1172/Jci117379  0.426
1994 Zimmerman GA, Elstad MR, Lorant DE, Patel KD, Topham MK, Whatley RE, McIntyre TM, Prescott SM. Platelet-activating factor: New roles in cell-cell interactions Journal of Lipid Mediators and Cell Signalling. 10: 57-59.  0.32
1993 Stafforini DM, Rollins EN, Prescott SM, McIntyre TM. The platelet-activating factor acetylhydrolase from human erythrocytes: Purification and properties Journal of Biological Chemistry. 268: 3857-3865. PMID 8440681  0.331
1993 Venable ME, Zimmerman GA, McIntyre TM, Prescott SM. Platelet-activating factor: a phospholipid autacoid with diverse actions. Journal of Lipid Research. 34: 691-702. PMID 8389794  0.32
1993 Patel KD, Lorant E, Jones DA, Prescott M, McIntyre TM, Zimmerman GA. Juxtacrine interactions of endothelial cells with leukocytes: tethering and signaling molecules. Behring Institute Mitteilungen. 144-64. PMID 8250808  0.339
1993 Lorant DE, Topham MK, Whatley RE, McEver RP, McIntyre TM, Prescott SM, Zimmerman GA. Inflammatory roles of P-selectin. The Journal of Clinical Investigation. 92: 559-70. PMID 7688760 DOI: 10.1172/Jci116623  0.425
1992 Holland MR, Venable ME, Whatley RE, Zimmerman GA, McIntyre TM, Prescott SM. Activation of the acetyl-coenzyme A:lysoplatelet-activating factor acetyltransferase regulates platelet-activating factor synthesis in human endothelial cells. The Journal of Biological Chemistry. 267: 22883-90. PMID 1429636  0.37
1992 Zimmerman GA, Prescott SM, McIntyre TM. Endothelial cell interactions with granulocytes: tethering and signaling molecules. Immunology Today. 13: 93-100. PMID 1377920 DOI: 10.1016/0167-5699(92)90149-2  0.381
1992 Carveth HJ, Shaddy RE, Whatley RE, McIntyre TM, Prescott SM, Zimmerman GA. Regulation of platelet-activating factor (PAF) synthesis and PAF-mediated neutrophil adhesion to endothelial cells activated by thrombin. Seminars in Thrombosis and Hemostasis. 18: 126-34. PMID 1315452 DOI: 10.1055/S-2007-1002417  0.517
1991 Holland MR, McIntyre TM, Zimmerman GA, Prescott SM. Cardiovascular effects of platelet-activating factor. Trends in Cardiovascular Medicine. 1: 117-21. PMID 21239326 DOI: 10.1016/1050-1738(91)90005-Y  0.458
1991 Elstad MR, Stafforini DM, Prescott SM, McIntyre TM, Zimmerman GA. Human macrophages secrete platelet-activating factor acetylhydrolase. A mechanism for resolution of pulmonary inflammation. Chest. 99: 9S-10S. PMID 1997289  0.315
1991 Stafforini DM, Prescott SM, McIntyre TM. Platelet-activating factor acetylhydrolase in human erythrocytes Methods in Enzymology. 197: 411-425. PMID 1904975 DOI: 10.1016/0076-6879(91)97167-W  0.375
1991 Elstad MR, McIntyre TM, Prescott SM, Zimmerman GA. Protein kinase C regulates the synthesis of platelet-activating factor by human monocytes. American Journal of Respiratory Cell and Molecular Biology. 4: 148-55. PMID 1846746 DOI: 10.1165/Ajrcmb/4.2.148  0.432
1991 Stafforini DM, Prescott SM, Zimmerman GA, McIntyre TM. Platelet-activating factor acetylhydrolase activity in human tissues and blood cells. Lipids. 26: 979-85. PMID 1819753 DOI: 10.1007/Bf02536488  0.415
1991 Lorant DE, Patel KD, McIntyre TM, McEver RP, Prescott SM, Zimmerman GA. Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils. The Journal of Cell Biology. 115: 223-34. PMID 1717478 DOI: 10.1083/Jcb.115.1.223  0.394
1991 Patel KD, Zimmerman GA, Prescott SM, McEver RP, McIntyre TM. Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils. The Journal of Cell Biology. 112: 749-59. PMID 1704376 DOI: 10.1083/Jcb.112.4.749  0.4
1991 Fennell DF, Whatley RE, McIntyre TM, Prescott SM, Zimmerman GA. Endothelial cells reestablish functional integrity after reversible permeabilization. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 11: 97-106. PMID 1702990 DOI: 10.1161/01.Atv.11.1.97  0.377
1990 Stafforini DM, Elstad MR, McIntyre TM, Zimmerman GA, Prescott SM. Human macrophages secret platelet-activating factor acetylhydrolase. The Journal of Biological Chemistry. 265: 9682-7. PMID 2351664  0.3
1990 Prescott SM, McIntyre TM, Zimmerman GA. The role of platelet-activating factor in endothelial cells. Thrombosis and Haemostasis. 64: 99-103. PMID 2274933 DOI: 10.1055/S-0038-1647261  0.507
1990 Zimmerman GA, Whatley RE, McIntyre TM, Benson DM, Prescott SM. Endothelial cells for studies of platelet-activating factor and arachidonate metabolites. Methods in Enzymology. 187: 520-35. PMID 2233360 DOI: 10.1016/0076-6879(90)87059-C  0.45
1990 Stafforini DM, McIntyre TM, Prescott SM. Platelet-activating factor acetylhydrolase from human plasma Methods in Enzymology. 187: 344-357. PMID 2172738 DOI: 10.1016/0076-6879(90)87041-Z  0.422
1990 Prescott SM, Zimmerman GA, McIntyre TM. Platelet-activating factor. The Journal of Biological Chemistry. 265: 17381-4. PMID 2170377  0.327
1990 Zimmerman GA, McIntyre TM, Mehra M, Prescott SM. Endothelial cell-associated platelet-activating factor: a novel mechanism for signaling intercellular adhesion. The Journal of Cell Biology. 110: 529-40. PMID 2153685 DOI: 10.1083/Jcb.110.2.529  0.495
1990 Whatley RE, Zimmerman GA, McIntyre TM, Prescott SM. Lipid metabolism and signal transduction in endothelial cells. Progress in Lipid Research. 29: 45-63. PMID 2128404 DOI: 10.1016/0163-7827(90)90005-6  0.445
1990 Whatley RE, Fennell DF, Kurrus JA, Zimmerman GA, McIntyre TM, Prescott SM. Synthesis of platelet-activating factor by endothelial cells. The role of G proteins. The Journal of Biological Chemistry. 265: 15550-9. PMID 2118526  0.325
1990 Reinhold SL, Prescott SM, Zimmerman GA, McIntyre TM. Activation of human neutrophil phospholipase D by three separable mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 208-14. PMID 2105252 DOI: 10.1096/Fasebj.4.2.2105252  0.381
1990 Zimmerman GA, McIntyre TM, Prescott SM, Otsuka K. Brief review: molecular mechanisms of neutrophil binding to endothelium involving platelet-activating factor and cytokines. Journal of Lipid Mediators. 2: S31-43. PMID 1983465  0.306
1990 Geng JG, Bevilacqua MP, Moore KL, McIntyre TM, Prescott SM, Kim JM, Bliss GA, Zimmerman GA, McEver RP. Rapid neutrophil adhesion to activated endothelium mediated by GMP-140. Nature. 343: 757-60. PMID 1689464 DOI: 10.1038/343757A0  0.476
1989 Stafforini DM, Carter ME, Zimmerman GA, McIntyre TM, Prescott SM. Lipoproteins alter the catalytic behavior of the platelet-activating factor acetylhydrolase in human plasma. Proceedings of the National Academy of Sciences of the United States of America. 86: 2393-7. PMID 2928339 DOI: 10.1073/Pnas.86.7.2393  0.35
1989 Elstad MR, Stafforini DM, McIntyre TM, Prescott SM, Zimmerman GA. Platelet-activating factor acetylhydrolase increases during macrophage differentiation. A novel mechanism that regulates accumulation of platelet-activating factor. The Journal of Biological Chemistry. 264: 8467-70. PMID 2722780  0.363
1989 Carveth HJ, Bohnsack JF, McIntyre TM, Baggiolini M, Prescott SM, Zimmerman GA. Neutrophil activating factor (NAF) induces polymorphonuclear leukocyte adherence to endothelial cells and to subendothelial matrix proteins. Biochemical and Biophysical Research Communications. 162: 387-93. PMID 2665743 DOI: 10.1016/0006-291X(89)92009-3  0.461
1988 Whatley RE, Lewis MS, Zimmerman GA, McIntyre TM, Parker CJ, Stevens DL, Prescott SM. The regulation of synthesis of platelet-activating factor by endothelial cells. Chest. 93: 110S-111S. PMID 3342689 DOI: 10.1378/Chest.93.3_Supplement.110S  0.494
1988 Lewis MS, Whatley RE, Cain P, McIntyre TM, Prescott SM, Zimmerman GA. Hydrogen peroxide stimulates the synthesis of platelet-activating factor by endothelium and induces endothelial cell-dependent neutrophil adhesion. The Journal of Clinical Investigation. 82: 2045-55. PMID 3198764 DOI: 10.1172/JCI113825  0.335
1988 Whatley RE, Zimmerman GA, McIntyre TM, Prescott SM. Endothelium from diverse vascular sources synthesizes platelet-activating factor. Arteriosclerosis (Dallas, Tex.). 8: 321-31. PMID 3130833 DOI: 10.1161/01.Atv.8.3.321  0.375
1988 Elstad MR, Prescott SM, McIntyre TM, Zimmerman GA. Synthesis and release of platelet-activating factor by stimulated human mononuclear phagocytes. Journal of Immunology (Baltimore, Md. : 1950). 140: 1618-24. PMID 3126231  0.342
1988 Zimmerman GA, McIntyre TM. Neutrophil adherence to human endothelium in vitro occurs by CDw18 (Mo1, MAC-1/LFA-1/GP 150,95) glycoprotein-dependent and -independent mechanisms. The Journal of Clinical Investigation. 81: 531-7. PMID 2828429 DOI: 10.1172/Jci113351  0.443
1987 Stafforini DM, McIntyre TM, Carter ME, Prescott SM. Human plasma platelet-activating factor acetylhydrolase. Association with lipoprotein particles and role in the degradation of platelet-activating factor. The Journal of Biological Chemistry. 262: 4215-22. PMID 3549727  0.322
1987 Whatley RE, Zimmerman GA, McIntyre TM, Taylor R, Prescott SM. Production of platelet-activating factor by endothelial cells. Seminars in Thrombosis and Hemostasis. 13: 445-53. PMID 3321437 DOI: 10.1055/S-2007-1003521  0.457
1987 Zimmerman GA, Whatley RE, McIntyre TM, Prescott SM. Production of platelet-activating factor, a biologically active lipid, by vascular endothelial cells. The American Review of Respiratory Disease. 136: 204-7. PMID 3300444 DOI: 10.1164/Ajrccm/136.1.204  0.44
1987 Sisson JH, Prescott SM, McIntyre TM, Zimmerman GA. Production of platelet-activating factor by stimulated human polymorphonuclear leukocytes. Correlation of synthesis with release, functional events, and leukotriene B4 metabolism. Journal of Immunology (Baltimore, Md. : 1950). 138: 3918-26. PMID 3035016  0.342
1986 Zimmerman GA, McIntyre TM, Prescott SM. Thrombin stimulates neutrophil adherence by an endothelial cell-dependent mechanism: characterization of the response and relationship to platelet-activating factor synthesis. Annals of the New York Academy of Sciences. 485: 349-68. PMID 3471149 DOI: 10.1111/J.1749-6632.1986.Tb34596.X  0.461
1986 McIntyre TM, Zimmerman GA, Prescott SM. Leukotrienes C4 and D4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils. Proceedings of the National Academy of Sciences of the United States of America. 83: 2204-8. PMID 3457383 DOI: 10.1073/Pnas.83.7.2204  0.443
1985 Zimmerman GA, McIntyre TM, Prescott SM. Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro. The Journal of Clinical Investigation. 76: 2235-46. PMID 4077977 DOI: 10.1172/Jci112232  0.414
1985 Zimmerman GA, McIntyre TM, Prescott SM. Production of platelet-activating factor by human vascular endothelial cells: evidence for a requirement for specific agonists and modulation by prostacyclin. Circulation. 72: 718-27. PMID 3928193  0.378
1985 McIntyre TM, Zimmerman GA, Satoh K, Prescott SM. Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate. The Journal of Clinical Investigation. 76: 271-80. PMID 2862164 DOI: 10.1172/JCI111957  0.392
1984 Prescott SM, Zimmerman GA, McIntyre TM. Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin. Proceedings of the National Academy of Sciences of the United States of America. 81: 3534-8. PMID 6587368 DOI: 10.1073/Pnas.81.11.3534  0.487
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