Cheng-Jun Hu - Publications

Affiliations: 
Molecular Biology University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Molecular Biology

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Plecitá-Hlavatá L, Brázdová A, Křivonosková M, Hu CJ, Phang T, Tauber J, Li M, Zhang H, Hoetzenecker K, Crnkovic S, Kwapiszewska G, Stenmark KR. Microenvironmental regulation of T-cells in pulmonary hypertension. Frontiers in Immunology. 14: 1223122. PMID 37497214 DOI: 10.3389/fimmu.2023.1223122  0.289
2023 Li M, Plecitá-Hlavatá L, Dobrinskikh E, McKeon BA, Gandjeva A, Riddle S, Laux A, Prasad RR, Kumar S, Tuder RM, Zhang H, Hu CJ, Stenmark KR. SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension. American Journal of Respiratory Cell and Molecular Biology. PMID 37343939 DOI: 10.1165/rcmb.2022-0360OC  0.265
2023 Zhang H, Gerasimovskaya E, McCarthy MK, May NA, Prasad RR, Riddle S, McKeon BA, Kumar S, Li M, Hu CJ, Frid MG, Morrison TE, Stenmark KR. Local Complement Contributes to Pathogenic Activation of Lung Endothelial Cells in SARS-CoV-2 Infection. American Journal of Respiratory Cell and Molecular Biology. PMID 37071849 DOI: 10.1165/rcmb.2022-0373OC  0.282
2023 Brown RD, Hunter KS, Li M, Frid MG, Harral JW, Krafsur GM, Holt TN, Williams J, Zhang H, Riddle SR, Edwards MG, Kumar S, Hu CJ, Graham BB, Walker LA, et al. Functional and Molecular Determinants of Right Ventricular Response to Severe Pulmonary Hypertension in a Large Animal Model Am J Physiol Heart Circ Physiol. PMID 36961489  0.241
2023 Hu C. The Effect of HIF Inhibition on the Phenotype of Fibroblasts in Human and Bovine Pulmonary Hypertension American Journal of Respiratory Cell and Molecular Biology. PMID 36944195  0.296
2023 Kleczko EK, Le AT, Hinz TK, Nguyen TT, Navarro A, Hu CJ, Selman AM, Clambey ET, Merrick DT, Lu S, Weiser-Evans M, Nemenoff RA, Heasley LE. Novel EGFR-mutant mouse models of lung adenocarcinoma reveal adaptive immunity requirement for durable osimertinib response. Cancer Letters. 216062. PMID 36657561 DOI: 10.1016/j.canlet.2023.216062  0.255
2021 Zhang H, Laux A, Stenmark KR, Hu CJ. Mechanisms Contributing to the Dysregulation of miRNA-124 in Pulmonary Hypertension. International Journal of Molecular Sciences. 22. PMID 33917769 DOI: 10.3390/ijms22083852  0.302
2021 Li M, Riddle S, Kumar S, Poczobutt J, McKeon BA, Frid MG, Ostaff M, Reisz JA, Nemkov T, Fini MA, Laux A, Hu CJ, El Kasmi KC, D'Alessandro A, Brown RD, et al. Microenvironmental Regulation of Macrophage Transcriptomic and Metabolomic Profiles in Pulmonary Hypertension. Frontiers in Immunology. 12: 640718. PMID 33868271 DOI: 10.3389/fimmu.2021.640718  0.367
2020 Zhang H, Brown RD, Stenmark KR, Hu CJ. RNA-Binding Proteins in Pulmonary Hypertension. International Journal of Molecular Sciences. 21. PMID 32466553 DOI: 10.3390/Ijms21113757  0.503
2020 Joshi SR, Kitagawa A, Jacob C, Hashimoto R, Dhagia V, Ramesh A, Zheng C, Zhang H, Jordan A, Waddell I, Leopold JA, Hu CJ, McMurtry IF, D'Alessandro A, Stenmark KR, et al. Hypoxic Activation of G6PD Controls the Expression of Genes Involved in the Pathogenesis of Pulmonary Hypertension Through the Regulation of DNA Methylation. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32159369 DOI: 10.1152/Ajplung.00001.2020  0.518
2019 Hu CJ, Poth JM, Zhang H, Flockton A, Laux A, Kumar S, McKeon B, Frid MG, Mouradian G, Li M, Riddle S, Pugliese SC, Brown RD, Wallace EM, Graham BB, et al. Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension. The European Respiratory Journal. PMID 31515405 DOI: 10.1183/13993003.00378-2019  0.513
2018 Hu CJ, Zhang H, Laux A, Pullamsetti SS, Stenmark KR. Mechanisms Contributing to Persistently Activated Cell Phenotypes in Pulmonary Hypertension. The Journal of Physiology. PMID 29920674 DOI: 10.1113/Jp275857  0.524
2018 Stenmark KR, Hu CJ, Pullamsetti SS. How Many Foxs Are There on the Road to Pulmonary Hypertension? American Journal of Respiratory and Critical Care Medicine. PMID 29694238 DOI: 10.1164/Rccm.201804-0702Ed  0.328
2017 Zhang H, Wang D, Li M, Plecitá-Hlavatá L, D'Alessandro A, Tauber J, Riddle S, Kumar S, Flockton AR, McKeon BA, Frid MG, Reisz JA, Caruso P, El Kasmi KC, Ježek P, ... ... Hu CJ, et al. The Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension is Regulated through a MiR-124/PTBP1/PKM Axis. Circulation. PMID 28972001 DOI: 10.1161/Circulationaha.117.028069  0.394
2014 Hu CJ. Hypoxia regulates RNA splicing of HIF targets. Oncoscience. 1: 500-1. PMID 25594055  0.46
2014 Villa JC, Chiu D, Brandes AH, Escorcia FE, Villa CH, Maguire WF, Hu CJ, de Stanchina E, Simon MC, Sisodia SS, Scheinberg DA, Li YM. Nontranscriptional role of Hif-1α in activation of γ-secretase and notch signaling in breast cancer. Cell Reports. 8: 1077-92. PMID 25131208 DOI: 10.1016/J.Celrep.2014.07.028  0.506
2014 Sena JA, Wang L, Heasley LE, Hu CJ. Hypoxia regulates alternative splicing of HIF and non-HIF target genes. Molecular Cancer Research : McR. 12: 1233-43. PMID 24850901 DOI: 10.1158/1541-7786.Mcr-14-0149  0.706
2014 Sena JA, Wang L, Pawlus MR, Hu CJ. HIFs enhance the transcriptional activation and splicing of adrenomedullin. Molecular Cancer Research : McR. 12: 728-41. PMID 24523299 DOI: 10.1158/1541-7786.Mcr-13-0607  0.782
2014 Storti F, Santambrogio S, Crowther LM, Otto T, Abreu-Rodríguez I, Kaufmann M, Hu CJ, Dame C, Fandrey J, Wenger RH, Hoogewijs D. A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression. Haematologica. 99: e45-8. PMID 24510339 DOI: 10.3324/Haematol.2013.102707  0.471
2014 Pawlus MR, Wang L, Hu CJ. STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells. Oncogene. 33: 1670-9. PMID 23604114 DOI: 10.1038/onc.2013.115  0.802
2014 Hu CJ. Hypoxia regulates RNA splicing of HIF targets Oncoscience. 1: 500-501. DOI: 10.18632/oncoscience.75  0.46
2013 Pawlus MR, Wang L, Murakami A, Dai G, Hu CJ. STAT3 or USF2 contributes to HIF target gene specificity. Plos One. 8: e72358. PMID 23991099 DOI: 10.1371/Journal.Pone.0072358  0.79
2013 Befani C, Mylonis I, Gkotinakou IM, Georgoulias P, Hu CJ, Simos G, Liakos P. Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells. The International Journal of Biochemistry & Cell Biology. 45: 2359-68. PMID 23958427 DOI: 10.1016/J.Biocel.2013.07.025  0.655
2013 Sena JA, Wang L, Hu CJ. BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genes. Molecular and Cellular Biology. 33: 3849-63. PMID 23897427 DOI: 10.1128/Mcb.00731-13  0.673
2013 You Q, Holt M, Yin H, Li G, Hu CJ, Ju C. Role of hepatic resident and infiltrating macrophages in liver repair after acute injury. Biochemical Pharmacology. 86: 836-43. PMID 23876342 DOI: 10.1016/J.Bcp.2013.07.006  0.353
2013 Pawlus MR, Hu CJ. Enhanceosomes as integrators of hypoxia inducible factor (HIF) and other transcription factors in the hypoxic transcriptional response. Cellular Signalling. 25: 1895-903. PMID 23707522 DOI: 10.1016/J.Cellsig.2013.05.018  0.797
2013 Hu C, Pawlus M, Sena J, Wang L. Abstract 2929: HIF is necessary, but not sufficient for the hypoxia response. Cancer Research. 73: 2929-2929. DOI: 10.1158/1538-7445.Am2013-2929  0.714
2012 Pawlus MR, Wang L, Ware K, Hu CJ. Upstream stimulatory factor 2 and hypoxia-inducible factor 2α (HIF2α) cooperatively activate HIF2 target genes during hypoxia. Molecular and Cellular Biology. 32: 4595-610. PMID 22966206 DOI: 10.1128/Mcb.00724-12  0.804
2012 Sena J, Wang L, Hu C. Abstract 3945: HIFs regulate alternative splicing of HIF target genes Cancer Research. 72: 3945-3945. DOI: 10.1158/1538-7445.Am2012-3945  0.671
2011 Pawlus M, Wang L, Sena J, Hu C. Abstract 2048: USF2 is HIF2α specific co-transcriptional activator Cellular and Molecular Biology. 71: 2048-2048. DOI: 10.1158/1538-7445.Am2011-2048  0.756
2007 Hu CJ, Sataur A, Wang L, Chen H, Simon MC. The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha. Molecular Biology of the Cell. 18: 4528-42. PMID 17804822 DOI: 10.1091/Mbc.E06-05-0419  0.554
2007 Gordan JD, Bertout JA, Hu CJ, Diehl JA, Simon MC. HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity. Cancer Cell. 11: 335-47. PMID 17418410 DOI: 10.1016/J.Ccr.2007.02.006  0.529
2007 Gruber M, Hu CJ, Johnson RS, Brown EJ, Keith B, Simon MC. Acute postnatal ablation of Hif-2alpha results in anemia. Proceedings of the National Academy of Sciences of the United States of America. 104: 2301-6. PMID 17284606 DOI: 10.1073/Pnas.0608382104  0.479
2007 Diez H, Fischer A, Winkler A, Hu CJ, Hatzopoulos AK, Breier G, Gessler M. Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate. Experimental Cell Research. 313: 1-9. PMID 17045587 DOI: 10.1016/J.Yexcr.2006.09.009  0.586
2006 Hu CJ, Iyer S, Sataur A, Covello KL, Chodosh LA, Simon MC. Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells. Molecular and Cellular Biology. 26: 3514-26. PMID 16611993 DOI: 10.1128/Mcb.26.9.3514-3526.2006  0.536
2006 Covello KL, Kehler J, Yu H, Gordan JD, Arsham AM, Hu CJ, Labosky PA, Simon MC, Keith B. HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes & Development. 20: 557-70. PMID 16510872 DOI: 10.1101/Gad.1399906  0.563
2003 Hu CJ, Wang LY, Chodosh LA, Keith B, Simon MC. Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Molecular and Cellular Biology. 23: 9361-74. PMID 14645546 DOI: 10.1128/Mcb.23.24.9361-9374.2003  0.528
2000 Hu CJ, Gupta KC. Functional significance of alternate phosphorylation in Sendai virus P protein Virology. 268: 517-532. PMID 10704359 DOI: 10.1006/Viro.1999.0176  0.349
1999 Hu CJ, Kato A, Bowman MC, Kiyotani K, Yoshida T, Moyer SA, Nagai Y, Gupta KC. Role of primary constitutive phosphorylation of Sendai virus P and V proteins in viral replication and pathogenesis. Virology. 263: 195-208. PMID 10544094 DOI: 10.1006/Viro.1999.9953  0.379
1996 Zhang JF, Hu C, Geng Y, Selm J, Klein SB, Orazi A, Taylor MW. Treatment of a human breast cancer xenograft with an adenovirus vector containing an interferon gene results in rapid regression due to viral oncolysis and gene therapy Proceedings of the National Academy of Sciences of the United States of America. 93: 4513-4518. PMID 8633100 DOI: 10.1073/Pnas.93.9.4513  0.431
1995 Hu CJ, Ozes ON, Klein SB, Blatt LM, Taylor MW. Comparison of the in vitro host range of recombinant met-interferon-con1, interferon-α(2a), and interferon-β Journal of Interferon and Cytokine Research. 15: 231-234. PMID 7584668 DOI: 10.1089/jir.1995.15.231  0.254
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