Year |
Citation |
Score |
2023 |
Shukla R, Peoples AJ, Ludwig KC, Maity S, Derks MGN, De Benedetti S, Krueger AM, Vermeulen BJA, Harbig T, Lavore F, Kumar R, Honorato RV, Grein F, Nieselt K, Liu Y, ... ... Lewis K, et al. An antibiotic from an uncultured bacterium binds to an immutable target. Cell. PMID 37611581 DOI: 10.1016/j.cell.2023.07.038 |
0.336 |
|
2023 |
Chen CW, Leimer N, Syroegin EA, Dunand C, Bulman ZP, Lewis K, Polikanov YS, Svetlov MS. Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nature Communications. 14: 4196. PMID 37452045 DOI: 10.1038/s41467-023-39653-5 |
0.334 |
|
2023 |
Shukla R, Peoples AJ, Ludwig KC, Maity S, Derks MGN, de Benedetti S, Krueger AM, Vermeulen BJA, Lavore F, Honorato RV, Grein F, Bonvin A, Kubitscheck U, Breukink E, Achorn C, ... ... Lewis K, et al. A new antibiotic from an uncultured bacterium binds to an immutable target. Biorxiv : the Preprint Server For Biology. PMID 37292624 DOI: 10.1101/2023.05.15.540765 |
0.337 |
|
2022 |
Blaskovich MAT, Hansford KA, Butler MS, Ramu S, Kavanagh AM, Jarrad AM, Prasetyoputri A, Pitt ME, Huang JX, Lindahl F, Ziora ZM, Bradford T, Muldoon C, Rajaratnam P, Pelingon R, ... ... Lewis K, et al. A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine. 14: eabj2381. PMID 36103517 DOI: 10.1126/scitranslmed.abj2381 |
0.361 |
|
2022 |
Shahsavari N, Wang B, Imai Y, Mori M, Son S, Liang L, Böhringer N, Manuse S, Gates MF, Morrissette M, Corsetti R, Espinoza JL, Dupont CL, Laub MT, Lewis K. A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP. Mbio. e0070022. PMID 35575547 DOI: 10.1128/mbio.00700-22 |
0.377 |
|
2022 |
Nicolau SE, Lewis K. The Role of Integration Host Factor in Escherichia coli Persister Formation. Mbio. e0342021. PMID 34982597 DOI: 10.1128/mbio.03420-21 |
0.3 |
|
2021 |
Böhringer N, Green R, Liu Y, Mettal U, Marner M, Modaresi SM, Jakob RP, Wuisan ZG, Maier T, Iinishi A, Hiller S, Lewis K, Schäberle TF. Mutasynthetic Production and Antimicrobial Characterization of Darobactin Analogs. Microbiology Spectrum. 9: e0153521. PMID 34937193 DOI: 10.1128/spectrum.01535-21 |
0.357 |
|
2021 |
Crüsemann M, Wirtz DA, Ludwig KC, Arts M, Marx CE, Krannich S, Barac P, Kehraus S, Josten M, Henrichfreise B, Müller A, König GM, Peoples AJ, Nitti A, Spoering AL, ... ... Lewis K, et al. Biosynthesis and mechanism of action of the cell wall targeting antibiotic hypeptin. Angewandte Chemie (International Ed. in English). PMID 33768646 DOI: 10.1002/anie.202102224 |
0.318 |
|
2020 |
Quigley J, Peoples A, Sarybaeva A, Hughes D, Ghiglieri M, Achorn C, Desrosiers A, Felix C, Liang L, Malveira S, Millett W, Nitti A, Tran B, Zullo A, Anklin C, ... ... Lewis K, et al. Novel Antimicrobials from Uncultured Bacteria Acting against Mycobacterium tuberculosis. Mbio. 11. PMID 32753498 DOI: 10.1128/Mbio.01516-20 |
0.384 |
|
2020 |
Imai Y, Meyer KJ, Iinishi A, Favre-Godal Q, Green R, Manuse S, Caboni M, Mori M, Niles S, Ghiglieri M, Honrao C, Ma X, Guo JJ, Makriyannis A, Linares-Otoya L, ... ... Lewis K, et al. Author Correction: A new antibiotic selectively kills Gram-negative pathogens. Nature. 580: E3. PMID 32269338 DOI: 10.1038/S41586-020-2063-9 |
0.365 |
|
2020 |
Lewis K. The Science of Antibiotic Discovery. Cell. PMID 32197064 DOI: 10.1016/J.Cell.2020.02.056 |
0.423 |
|
2020 |
Morris MA, Malek M, Hashemian MH, Nguyen BT, Manuse S, Lewis K, Nowick JS. A Fluorescent Teixobactin Analogue. Acs Chemical Biology. PMID 32045203 DOI: 10.1021/Acschembio.9B00908 |
0.362 |
|
2020 |
O'Rourke A, Beyhan S, Choi Y, Morales P, Chan AP, Espinoza JL, Dupont CL, Meyer KJ, Spoering A, Lewis K, Nierman WC, Nelson KE. Mechanism-Of-Action Classification of Antibiotics by Global Transcriptome Profiling. Antimicrobial Agents and Chemotherapy. PMID 31907190 DOI: 10.1128/Aac.01207-19 |
0.418 |
|
2019 |
Imai Y, Meyer KJ, Iinishi A, Favre-Godal Q, Green R, Manuse S, Caboni M, Mori M, Niles S, Ghiglieri M, Honrao C, Ma X, Guo J, Makriyannis A, Linares-Otoya L, ... ... Lewis K, et al. A new antibiotic selectively kills Gram-negative pathogens. Nature. PMID 31747680 DOI: 10.1038/S41586-019-1791-1 |
0.489 |
|
2019 |
O'Connor K, Morrissette M, Strandwitz P, Ghiglieri M, Caboni M, Liu H, Khoo C, D'Onofrio A, Lewis K. Cranberry extracts promote growth of Bacteroidaceae and decrease abundance of Enterobacteriaceae in a human gut simulator model. Plos One. 14: e0224836. PMID 31714906 DOI: 10.1371/Journal.Pone.0224836 |
0.415 |
|
2019 |
Zalis EA, Nuxoll AS, Manuse S, Clair G, Radlinski LC, Conlon BP, Adkins J, Lewis K. Stochastic Variation in Expression of the Tricarboxylic Acid Cycle Produces Persister Cells. Mbio. 10. PMID 31530676 DOI: 10.1128/Mbio.01930-19 |
0.447 |
|
2019 |
Zong Y, Fang F, Meyer KJ, Wang L, Ni Z, Gao H, Lewis K, Zhang J, Rao Y. Gram-scale total synthesis of teixobactin promoting binding mode study and discovery of more potent antibiotics. Nature Communications. 10: 3268. PMID 31332172 DOI: 10.1038/S41467-019-11211-Y |
0.427 |
|
2019 |
Balaban NQ, Helaine S, Lewis K, Ackermann M, Aldridge B, Andersson DI, Brynildsen MP, Bumann D, Camilli A, Collins JJ, Dehio C, Fortune S, Ghigo JM, Hardt WD, Harms A, et al. Definitions and guidelines for research on antibiotic persistence. Nature Reviews. Microbiology. PMID 30980069 DOI: 10.1038/S41579-019-0196-3 |
0.448 |
|
2018 |
Wu X, Sharma B, Niles S, O'Connor K, Schilling R, Matluck N, D'Onofrio A, Hu LT, Lewis K. Identifying vancomycin as an effective antibiotic for killing . Antimicrobial Agents and Chemotherapy. PMID 30126963 DOI: 10.1128/Aac.01201-18 |
0.44 |
|
2018 |
Cameron DR, Shan Y, Zalis EA, Isabella V, Lewis K. A genetic determinant of persister cell formation in bacterial pathogens. Journal of Bacteriology. PMID 29941425 DOI: 10.1128/Jb.00303-18 |
0.442 |
|
2018 |
Zong Y, Sun X, Gao H, Meyer KJ, Lewis K, Rao Y. Developing Equipotent Teixobactin Analogues against Drug-Resistant Bacteria and Discovering a Hydrophobic Interaction between Lipid II and Teixobactin. Journal of Medicinal Chemistry. PMID 29629769 DOI: 10.1021/Acs.Jmedchem.7B01241 |
0.342 |
|
2017 |
Fenn K, Strandwitz P, Stewart EJ, Dimise E, Rubin S, Gurubacharya S, Clardy J, Lewis K. Quinones are growth factors for the human gut microbiota. Microbiome. 5: 161. PMID 29262868 DOI: 10.1186/S40168-017-0380-5 |
0.32 |
|
2017 |
Lewis K, Caboni M. The Making of a Pathogen. Cell Host & Microbe. 21: 653-654. PMID 28618261 DOI: 10.1016/J.Chom.2017.06.001 |
0.355 |
|
2017 |
Lewis K, Shan Y. Why tolerance invites resistance. Science (New York, N.Y.). 355: 796. PMID 28232537 DOI: 10.1126/Science.Aam7926 |
0.451 |
|
2017 |
Shan Y, Brown Gandt A, Rowe SE, Deisinger JP, Conlon BP, Lewis K. ATP-Dependent Persister Formation in Escherichia coli. Mbio. 8. PMID 28174313 DOI: 10.1128/Mbio.02267-16 |
0.391 |
|
2016 |
Jones MB, Nierman WC, Shan Y, Frank BC, Spoering A, Ling L, Peoples A, Zullo A, Lewis K, Nelson KE. Reducing the Bottleneck in Discovery of Novel Antibiotics. Microbial Ecology. PMID 27896376 DOI: 10.1007/S00248-016-0889-3 |
0.365 |
|
2016 |
Lewis K. New Approaches to Antimicrobial Discovery. Biochemical Pharmacology. PMID 27823963 DOI: 10.1016/J.Bcp.2016.11.002 |
0.447 |
|
2016 |
Conlon BP, Rowe SE, Gandt AB, Nuxoll AS, Donegan NP, Zalis EA, Clair G, Adkins JN, Cheung AL, Lewis K. Persister formation in Staphylococcus aureus is associated with ATP depletion. Nature Microbiology. 1: 16051. PMID 27572649 DOI: 10.1038/Nmicrobiol.2016.51 |
0.464 |
|
2016 |
Homma T, Nuxoll A, Brown Gandt A, Ebner P, Engels I, Schneider T, Götz F, Lewis K, Conlon BP. Dual targeting of cell wall precursors by teixobactin leads to cell lysis. Antimicrobial Agents and Chemotherapy. PMID 27550357 DOI: 10.1128/Aac.01050-16 |
0.429 |
|
2016 |
Lewis K, Strandwitz P. Microbiology: Antibiotics right under our nose. Nature. 535: 501-2. PMID 27466121 DOI: 10.1038/535501A |
0.464 |
|
2016 |
Conlon BP, Rowe SE, Gandt AB, Nuxoll AS, Donegan NP, Zalis EA, Clair G, Adkins JN, Cheung AL, Lewis K. Persister formation in Staphylococcus aureus is associated with ATP depletion. Nature Microbiology. 1. PMID 27398229 DOI: 10.1038/nmicrobiol.2016.51 |
0.362 |
|
2016 |
Torrey HL, Keren I, Via LE, Lee JS, Lewis K. High Persister Mutants in Mycobacterium tuberculosis. Plos One. 11: e0155127. PMID 27176494 DOI: 10.1371/Journal.Pone.0155127 |
0.38 |
|
2016 |
Rowe SE, Conlon BP, Keren I, Lewis K. Persisters: Methods for Isolation and Identifying Contributing Factors-A Review. Methods in Molecular Biology (Clifton, N.J.). 1333: 17-28. PMID 26468096 DOI: 10.1007/978-1-4939-2854-5_2 |
0.356 |
|
2015 |
Dolla NK, Chen C, Larkins-Ford J, Rajamuthiah R, Jagadeesan S, Conery AL, Ausubel FM, Mylonakis E, Bremner JB, Lewis K, Kelso MJ. On the Mechanism of Berberine-INF55 (5-Nitro-2-phenylindole) Hybrid Antibacterials. Australian Journal of Chemistry. 67: 1471-1480. PMID 26806960 DOI: 10.1071/Ch14426 |
0.39 |
|
2015 |
Schumacher MA, Balani P, Min J, Chinnam NB, Hansen S, Vulić M, Lewis K, Brennan RG. HipBA-promoter structures reveal the basis of heritable multidrug tolerance. Nature. 524: 59-64. PMID 26222023 DOI: 10.1038/Nature14662 |
0.394 |
|
2015 |
Sharma B, Brown AV, Matluck NE, Hu LT, Lewis K. Borrelia burgdorferi, the Causative Agent of Lyme Disease, Forms Drug-Tolerant Persister Cells. Antimicrobial Agents and Chemotherapy. 59: 4616-24. PMID 26014929 DOI: 10.1128/Aac.00864-15 |
0.432 |
|
2015 |
Shan Y, Lazinski D, Rowe S, Camilli A, Lewis K. Genetic basis of persister tolerance to aminoglycosides in Escherichia coli. Mbio. 6. PMID 25852159 DOI: 10.1128/Mbio.00078-15 |
0.335 |
|
2015 |
Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, Mueller A, Schäberle TF, Hughes DE, Epstein S, Jones M, Lazarides L, Steadman VA, Cohen DR, Felix CR, ... ... Lewis K, et al. Erratum: A new antibiotic kills pathogens without detectable resistance. Nature. 520: 388. PMID 25731174 DOI: 10.1038/Nature14303 |
0.348 |
|
2015 |
Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, Mueller A, Schäberle TF, Hughes DE, Epstein S, Jones M, Lazarides L, Steadman VA, Cohen DR, Felix CR, ... ... Lewis K, et al. A new antibiotic kills pathogens without detectable resistance. Nature. 517: 455-9. PMID 25561178 DOI: 10.1038/Nature14098 |
0.482 |
|
2015 |
Conlon BP, Rowe SE, Lewis K. Persister cells in biofilm associated infections. Advances in Experimental Medicine and Biology. 831: 1-9. PMID 25384659 DOI: 10.1007/978-3-319-09782-4_1 |
0.415 |
|
2015 |
Lewis K. Challenges of antibiotic discovery: Antibiotic resistance and tolerance plus troubles with discovery platforms complicate efforts to identify useful antibacterial drug candidates Microbe. 10: 363-369. DOI: 10.1128/Microbe.10.363.1 |
0.463 |
|
2014 |
Gavrish E, Shrestha B, Chen C, Lister I, North EJ, Yang L, Lee RE, Han A, Williams B, Charnuska D, Coleman K, Lewis K, LaFleur MD. In vitro and in vivo activities of HPi1, a selective antimicrobial against Helicobacter pylori. Antimicrobial Agents and Chemotherapy. 58: 3255-60. PMID 24687512 DOI: 10.1128/Aac.02573-13 |
0.318 |
|
2014 |
Gavrish E, Sit CS, Cao S, Kandror O, Spoering A, Peoples A, Ling L, Fetterman A, Hughes D, Bissell A, Torrey H, Akopian T, Mueller A, Epstein S, Goldberg A, ... ... Lewis K, et al. Lassomycin, a ribosomally synthesized cyclic peptide, kills mycobacterium tuberculosis by targeting the ATP-dependent protease ClpC1P1P2. Chemistry & Biology. 21: 509-18. PMID 24684906 DOI: 10.1016/J.Chembiol.2014.01.014 |
0.412 |
|
2014 |
Chen C, Dolla NK, Casadei G, Bremner JB, Lewis K, Kelso MJ. Diarylacylhydrazones: Clostridium-selective antibacterials with activity against stationary-phase cells. Bioorganic & Medicinal Chemistry Letters. 24: 595-600. PMID 24360560 DOI: 10.1016/J.Bmcl.2013.12.015 |
0.362 |
|
2014 |
Fleck LE, North EJ, Lee RE, Mulcahy LR, Casadei G, Lewis K. A screen for and validation of prodrug antimicrobials. Antimicrobial Agents and Chemotherapy. 58: 1410-9. PMID 24342644 DOI: 10.1128/Aac.02136-13 |
0.447 |
|
2014 |
Mulcahy LR, Isabella VM, Lewis K. Pseudomonas aeruginosa biofilms in disease. Microbial Ecology. 68: 1-12. PMID 24096885 DOI: 10.1007/S00248-013-0297-X |
0.412 |
|
2013 |
Conlon BP, Nakayasu ES, Fleck LE, LaFleur MD, Isabella VM, Coleman K, Leonard SN, Smith RD, Adkins JN, Lewis K. Activated ClpP kills persisters and eradicates a chronic biofilm infection. Nature. 503: 365-70. PMID 24226776 DOI: 10.1038/Nature12790 |
0.443 |
|
2013 |
Theodore A, Lewis K, Vulic M. Tolerance of Escherichia coli to fluoroquinolone antibiotics depends on specific components of the SOS response pathway. Genetics. 195: 1265-76. PMID 24077306 DOI: 10.1534/Genetics.113.152306 |
0.383 |
|
2013 |
Balaban NQ, Gerdes K, Lewis K, McKinney JD. A problem of persistence: still more questions than answers? Nature Reviews. Microbiology. 11: 587-91. PMID 24020075 DOI: 10.1038/Nrmicro3076 |
0.451 |
|
2013 |
Lafleur MD, Sun L, Lister I, Keating J, Nantel A, Long L, Ghannoum M, North J, Lee RE, Coleman K, Dahl T, Lewis K. Potentiation of azole antifungals by 2-adamantanamine. Antimicrobial Agents and Chemotherapy. 57: 3585-92. PMID 23689724 DOI: 10.1128/Aac.00294-13 |
0.387 |
|
2013 |
Lewis K. Platforms for antibiotic discovery. Nature Reviews. Drug Discovery. 12: 371-87. PMID 23629505 DOI: 10.1038/Nrd3975 |
0.463 |
|
2013 |
Keren I, Wu Y, Inocencio J, Mulcahy LR, Lewis K. Killing by bactericidal antibiotics does not depend on reactive oxygen species. Science (New York, N.Y.). 339: 1213-6. PMID 23471410 DOI: 10.1126/Science.1232688 |
0.416 |
|
2012 |
Lewis K. Persister cells: molecular mechanisms related to antibiotic tolerance. Handbook of Experimental Pharmacology. 121-33. PMID 23090599 DOI: 10.1007/978-3-642-28951-4_8 |
0.466 |
|
2012 |
Keren I, Mulcahy LR, Lewis K. Persister eradication: lessons from the world of natural products. Methods in Enzymology. 517: 387-406. PMID 23084949 DOI: 10.1016/B978-0-12-404634-4.00019-X |
0.472 |
|
2012 |
Lechner S, Lewis K, Bertram R. Staphylococcus aureus persisters tolerant to bactericidal antibiotics. Journal of Molecular Microbiology and Biotechnology. 22: 235-44. PMID 22986269 DOI: 10.1159/000342449 |
0.425 |
|
2012 |
Wu Y, Vulić M, Keren I, Lewis K. Role of oxidative stress in persister tolerance. Antimicrobial Agents and Chemotherapy. 56: 4922-6. PMID 22777047 DOI: 10.1128/Aac.00921-12 |
0.414 |
|
2012 |
Hansen S, Vulić M, Min J, Yen TJ, Schumacher MA, Brennan RG, Lewis K. Regulation of the Escherichia coli HipBA toxin-antitoxin system by proteolysis. Plos One. 7: e39185. PMID 22720069 DOI: 10.1371/Journal.Pone.0039185 |
0.356 |
|
2012 |
Lewis K. Antibiotics: Recover the lost art of drug discovery. Nature. 485: 439-40. PMID 22622552 DOI: 10.1038/485439A |
0.384 |
|
2011 |
Bush K, Courvalin P, Dantas G, Davies J, Eisenstein B, Huovinen P, Jacoby GA, Kishony R, Kreiswirth BN, Kutter E, Lerner SA, Levy S, Lewis K, Lomovskaya O, Miller JH, et al. Tackling antibiotic resistance. Nature Reviews. Microbiology. 9: 894-6. PMID 22048738 DOI: 10.1038/Nrmicro2693 |
0.417 |
|
2011 |
Keren I, Minami S, Rubin E, Lewis K. Characterization and transcriptome analysis of Mycobacterium tuberculosis persisters. Mbio. 2: e00100-11. PMID 21673191 DOI: 10.1128/Mbio.00100-11 |
0.364 |
|
2011 |
Fiamegos YC, Kastritis PL, Exarchou V, Han H, Bonvin AM, Vervoort J, Lewis K, Hamblin MR, Tegos GP. Antimicrobial and efflux pump inhibitory activity of caffeoylquinic acids from Artemisia absinthium against gram-positive pathogenic bacteria. Plos One. 6: e18127. PMID 21483731 DOI: 10.1371/Journal.Pone.0018127 |
0.451 |
|
2011 |
LaFleur MD, Lucumi E, Napper AD, Diamond SL, Lewis K. Novel high-throughput screen against Candida albicans identifies antifungal potentiators and agents effective against biofilms. The Journal of Antimicrobial Chemotherapy. 66: 820-6. PMID 21393183 DOI: 10.1093/Jac/Dkq530 |
0.399 |
|
2011 |
Gurnev PA, Ortenberg R, Lewis K, Bezrukov SM. Protective Bacterial Toxin TisB Produces Well-Defined Anion-Selective Pores in Planar Lipid Bilayers Biophysical Journal. 100: 3-6. DOI: 10.1016/J.Bpj.2010.12.2041 |
0.302 |
|
2010 |
Mulcahy LR, Burns JL, Lory S, Lewis K. Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis. Journal of Bacteriology. 192: 6191-9. PMID 20935098 DOI: 10.1128/Jb.01651-09 |
0.421 |
|
2010 |
Bollmann A, Palumbo AV, Lewis K, Epstein SS. Isolation and physiology of bacteria from contaminated subsurface sediments. Applied and Environmental Microbiology. 76: 7413-9. PMID 20870785 DOI: 10.1128/Aem.00376-10 |
0.323 |
|
2010 |
Lewis K, Epstein S, D'Onofrio A, Ling LL. Uncultured microorganisms as a source of secondary metabolites. The Journal of Antibiotics. 63: 468-76. PMID 20648021 DOI: 10.1038/Ja.2010.87 |
0.335 |
|
2010 |
Lewis K. Persister cells. Annual Review of Microbiology. 64: 357-72. PMID 20528688 DOI: 10.1146/annurev.micro.112408.134306 |
0.318 |
|
2010 |
Tomkiewicz D, Casadei G, Larkins-Ford J, Moy TI, Garner J, Bremner JB, Ausubel FM, Lewis K, Kelso MJ. Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components. Antimicrobial Agents and Chemotherapy. 54: 3219-24. PMID 20498327 DOI: 10.1128/Aac.01715-09 |
0.394 |
|
2010 |
D'Onofrio A, Crawford JM, Stewart EJ, Witt K, Gavrish E, Epstein S, Clardy J, Lewis K. Siderophores from neighboring organisms promote the growth of uncultured bacteria. Chemistry & Biology. 17: 254-64. PMID 20338517 DOI: 10.1016/J.Chembiol.2010.02.010 |
0.347 |
|
2010 |
Dörr T, Vulić M, Lewis K. Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli. Plos Biology. 8: e1000317. PMID 20186264 DOI: 10.1371/Journal.Pbio.1000317 |
0.416 |
|
2010 |
Nichols D, Cahoon N, Trakhtenberg EM, Pham L, Mehta A, Belanger A, Kanigan T, Lewis K, Epstein SS. Use of ichip for high-throughput in situ cultivation of "uncultivable" microbial species. Applied and Environmental Microbiology. 76: 2445-50. PMID 20173072 DOI: 10.1128/Aem.01754-09 |
0.324 |
|
2010 |
Lafleur MD, Qi Q, Lewis K. Patients with long-term oral carriage harbor high-persister mutants of Candida albicans. Antimicrobial Agents and Chemotherapy. 54: 39-44. PMID 19841146 DOI: 10.1128/Aac.00860-09 |
0.389 |
|
2010 |
Lewis K. Persister cells and the paradox of chronic infections Microbe. 5: 429-437. DOI: 10.1128/Microbe.5.429.1 |
0.361 |
|
2009 |
Dörr T, Lewis K, Vulić M. SOS response induces persistence to fluoroquinolones in Escherichia coli. Plos Genetics. 5: e1000760. PMID 20011100 DOI: 10.1371/Journal.Pgen.1000760 |
0.433 |
|
2009 |
Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM. High-throughput screen for novel antimicrobials using a whole animal infection model. Acs Chemical Biology. 4: 527-33. PMID 19572548 DOI: 10.1021/Cb900084V |
0.36 |
|
2009 |
Samosorn S, Tanwirat B, Muhamad N, Casadei G, Tomkiewicz D, Lewis K, Suksamrarn A, Prammananan T, Gornall KC, Beck JL, Bremner JB. Antibacterial activity of berberine-NorA pump inhibitor hybrids with a methylene ether linking group. Bioorganic & Medicinal Chemistry. 17: 3866-72. PMID 19419877 DOI: 10.1016/J.Bmc.2009.04.028 |
0.328 |
|
2009 |
Schumacher MA, Piro KM, Xu W, Hansen S, Lewis K, Brennan RG. Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB. Science (New York, N.Y.). 323: 396-401. PMID 19150849 DOI: 10.1126/Science.1163806 |
0.344 |
|
2008 |
Hansen S, Lewis K, Vulić M. Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. Antimicrobial Agents and Chemotherapy. 52: 2718-26. PMID 18519731 DOI: 10.1128/Aac.00144-08 |
0.406 |
|
2008 |
Nichols D, Lewis K, Orjala J, Mo S, Ortenberg R, O'Connor P, Zhao C, Vouros P, Kaeberlein T, Epstein SS. Short peptide induces an "uncultivable" microorganism to grow in vitro. Applied and Environmental Microbiology. 74: 4889-97. PMID 18515474 DOI: 10.1128/Aem.00393-08 |
0.319 |
|
2008 |
Lewis K. Multidrug tolerance of biofilms and persister cells Current Topics in Microbiology and Immunology. 322: 107-131. PMID 18453274 DOI: 10.1007/978-3-540-75418-3_6 |
0.491 |
|
2008 |
Lewis K, Epstein S, Godoy VG, Hong SH. Intact DNA in ancient permafrost. Trends in Microbiology. 16: 92-4. PMID 18291656 DOI: 10.1016/J.Tim.2008.01.002 |
0.307 |
|
2008 |
Gavrish E, Bollmann A, Epstein S, Lewis K. A trap for in situ cultivation of filamentous actinobacteria. Journal of Microbiological Methods. 72: 257-62. PMID 18255181 DOI: 10.1016/J.Mimet.2007.12.009 |
0.312 |
|
2007 |
Lewis K. Persister cells, dormancy and infectious disease. Nature Reviews. Microbiology. 5: 48-56. PMID 17143318 DOI: 10.1038/Nrmicro1557 |
0.417 |
|
2006 |
Ball AR, Casadei G, Samosorn S, Bremner JB, Ausubel FM, Moy TI, Lewis K. Conjugating berberine to a multidrug efflux pump inhibitor creates an effective antimicrobial. Acs Chemical Biology. 1: 594-600. PMID 17168555 DOI: 10.1021/Cb600238X |
0.473 |
|
2006 |
Correia FF, D'Onofrio A, Rejtar T, Li L, Karger BL, Makarova K, Koonin EV, Lewis K. Kinase activity of overexpressed HipA is required for growth arrest and multidrug tolerance in Escherichia coli. Journal of Bacteriology. 188: 8360-7. PMID 17041039 DOI: 10.1128/Jb.01237-06 |
0.342 |
|
2006 |
LaFleur MD, Kumamoto CA, Lewis K. Candida albicans biofilms produce antifungal-tolerant persister cells. Antimicrobial Agents and Chemotherapy. 50: 3839-46. PMID 16923951 DOI: 10.1128/Aac.00684-06 |
0.46 |
|
2006 |
Spoering AL, Vulic M, Lewis K. GlpD and PlsB participate in persister cell formation in Escherichia coli. Journal of Bacteriology. 188: 5136-44. PMID 16816185 DOI: 10.1128/Jb.00369-06 |
0.428 |
|
2006 |
Moy TI, Ball AR, Anklesaria Z, Casadei G, Lewis K, Ausubel FM. Identification of novel antimicrobials using a live-animal infection model. Proceedings of the National Academy of Sciences of the United States of America. 103: 10414-9. PMID 16801562 DOI: 10.1073/Pnas.0604055103 |
0.421 |
|
2006 |
Shah D, Zhang Z, Khodursky A, Kaldalu N, Kurg K, Lewis K. Persisters: a distinct physiological state of E. coli. Bmc Microbiology. 6: 53. PMID 16768798 DOI: 10.1186/1471-2180-6-53 |
0.431 |
|
2006 |
Belofsky G, Carreno R, Lewis K, Ball A, Casadei G, Tegos GP. Metabolites of the "smoke tree", Dalea spinosa, potentiate antibiotic activity against multidrug-resistant Staphylococcus aureus. Journal of Natural Products. 69: 261-4. PMID 16499327 DOI: 10.1021/Np058057S |
0.439 |
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2006 |
Samosorn S, Bremner JB, Ball A, Lewis K. Synthesis of functionalized 2-aryl-5-nitro-1H-indoles and their activity as bacterial NorA efflux pump inhibitors. Bioorganic & Medicinal Chemistry. 14: 857-65. PMID 16203150 DOI: 10.1016/J.Bmc.2005.09.019 |
0.374 |
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2005 |
Lewis K, Klibanov AM. Surpassing nature: rational design of sterile-surface materials. Trends in Biotechnology. 23: 343-8. PMID 15922467 DOI: 10.1016/J.Tibtech.2005.05.004 |
0.367 |
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2005 |
Milović NM, Wang J, Lewis K, Klibanov AM. Immobilized N-alkylated polyethylenimine avidly kills bacteria by rupturing cell membranes with no resistance developed. Biotechnology and Bioengineering. 90: 715-22. PMID 15803464 DOI: 10.1002/Bit.20454 |
0.422 |
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2005 |
Lewis K. Persister cells and the riddle of biofilm survival Biokhimiya. 70: 327-336. DOI: 10.1007/S10541-005-0111-6 |
0.446 |
|
2005 |
Lewis K. Persister cells and the riddle of biofilm survival Biokhimiya. 70: 327-336. DOI: 10.1007/s10541-005-0111-6 |
0.343 |
|
2004 |
Keren I, Shah D, Spoering A, Kaldalu N, Lewis K. Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli. Journal of Bacteriology. 186: 8172-80. PMID 15576765 DOI: 10.1128/Jb.186.24.8172-8180.2004 |
0.435 |
|
2004 |
Belofsky G, Percivill D, Lewis K, Tegos GP, Ekart J. Phenolic metabolites of Dalea versicolor that enhance antibiotic activity against model pathogenic bacteria. Journal of Natural Products. 67: 481-4. PMID 15043439 DOI: 10.1021/Np030409C |
0.419 |
|
2004 |
Kaldalu N, Mei R, Lewis K. Killing by ampicillin and ofloxacin induces overlapping changes in Escherichia coli transcription profile. Antimicrobial Agents and Chemotherapy. 48: 890-6. PMID 14982780 DOI: 10.1128/Aac.48.3.890-896.2004 |
0.375 |
|
2004 |
Keren I, Kaldalu N, Spoering A, Wang Y, Lewis K. Persister cells and tolerance to antimicrobials. Fems Microbiology Letters. 230: 13-8. PMID 14734160 DOI: 10.1016/S0378-1097(03)00856-5 |
0.546 |
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2004 |
Keren I, Kaldalu N, Spoering A, Wang Y, Lewis K. Corrigendum to: “Persister cells and tolerance to antimicrobials” [FEMS Microbiol. Lett. 230 (2003) 12–18] Fems Microbiology Letters. 234: 187-187. DOI: 10.1111/J.1574-6968.2004.Tb09532.X |
0.403 |
|
2003 |
Morel C, Stermitz FR, Tegos G, Lewis K. Isoflavones as potentiators of antibacterial activity. Journal of Agricultural and Food Chemistry. 51: 5677-9. PMID 12952418 DOI: 10.1021/Jf0302714 |
0.411 |
|
2003 |
Lin J, Qiu S, Lewis K, Klibanov AM. Mechanism of bactericidal and fungicidal activities of textiles covalently modified with alkylated polyethylenimine. Biotechnology and Bioengineering. 83: 168-72. PMID 12768622 DOI: 10.1002/Bit.10651 |
0.349 |
|
2003 |
Stermitz FR, Cashman KK, Halligan KM, Morel C, Tegos GP, Lewis K. Polyacylated neohesperidosides from Geranium caespitosum: bacterial multidrug resistance pump inhibitors. Bioorganic & Medicinal Chemistry Letters. 13: 1915-8. PMID 12749897 DOI: 10.1016/S0960-894X(03)00316-0 |
0.44 |
|
2002 |
Stermitz FR, Scriven LN, Tegos G, Lewis K. Two flavonols from Artemisa annua which potentiate the activity of berberine and norfloxacin against a resistant strain of Staphylococcus aureus. Planta Medica. 68: 1140-1. PMID 12494348 DOI: 10.1055/S-2002-36347 |
0.411 |
|
2002 |
Tegos G, Stermitz FR, Lomovskaya O, Lewis K. Multidrug pump inhibitors uncover remarkable activity of plant antimicrobials. Antimicrobial Agents and Chemotherapy. 46: 3133-41. PMID 12234835 DOI: 10.1128/Aac.46.10.3133-3141.2002 |
0.425 |
|
2002 |
Kaeberlein T, Lewis K, Epstein SS. Isolating "uncultivable" microorganisms in pure culture in a simulated natural environment. Science (New York, N.Y.). 296: 1127-9. PMID 12004133 DOI: 10.1126/Science.1070633 |
0.347 |
|
2002 |
Lin J, Tiller JC, Lee SB, Lewis K, Klibanov AM. Insights into bactericidal action of surface-attached poly(vinyl-N-hexylpyridinium) chains Biotechnology Letters. 24: 801-805. DOI: 10.1023/A:1015584423358 |
0.378 |
|
2001 |
Spoering AL, Lewis K. Biofilms and planktonic cells of Pseudomonas aeruginosa have similar resistance to killing by antimicrobials. Journal of Bacteriology. 183: 6746-6751. PMID 11698361 DOI: 10.1128/Jb.183.23.6746-6751.2001 |
0.436 |
|
2001 |
Stermitz FR, Beeson TD, Mueller PJ, Hsiang J, Lewis K. Staphylococcus aureus MDR efflux pump inhibitors from a Berberis and a Mahonia (sensu strictu) species. Biochemical Systematics and Ecology. 29: 793-798. PMID 11412952 DOI: 10.1016/S0305-1978(01)00025-4 |
0.38 |
|
2001 |
Tiller JC, Liao CJ, Lewis K, Klibanov AM. Designing surfaces that kill bacteria on contact. Proceedings of the National Academy of Sciences of the United States of America. 98: 5981-5. PMID 11353851 DOI: 10.1073/Pnas.111143098 |
0.37 |
|
2001 |
Lewis K. Riddle of biofilm resistance Antimicrobial Agents and Chemotherapy. 45: 999-1007. PMID 11257008 DOI: 10.1128/Aac.45.4.999-1007.2001 |
0.472 |
|
2001 |
Guz NR, Stermitz FR, Johnson JB, Beeson TD, Willen S, Hsiang J, Lewis K. Flavonolignan and flavone inhibitors of a Staphylococcus aureus multidrug resistance pump: structure-activity relationships. Journal of Medicinal Chemistry. 44: 261-8. PMID 11170636 DOI: 10.1021/Jm0004190 |
0.36 |
|
2001 |
Lewis K, Salyers A, Taber H, Wax R. Bacterial resistance to antimicrobials. South African Medical Journal. 43: 26-30. DOI: 10.1201/9780824744939 |
0.403 |
|
2000 |
Lewis K. Translocases: A bacterial tunnel for drugs and proteins Current Biology. 10. PMID 10996810 DOI: 10.1016/S0960-9822(00)00682-5 |
0.333 |
|
2000 |
Stermitz FR, Tawara-Matsuda J, Lorenz P, Mueller P, Zenewicz L, Lewis K. 5'-Methoxyhydnocarpin-D and pheophorbide A: Berberis species components that potentiate berberine growth inhibition of resistant Staphylococcus aureus. Journal of Natural Products. 63: 1146-9. PMID 10978214 DOI: 10.1021/Np990639K |
0.43 |
|
2000 |
Lewis K. Programmed death in bacteria Microbiology and Molecular Biology Reviews. 64: 503-514. PMID 10974124 DOI: 10.1128/Mmbr.64.3.503-514.2000 |
0.414 |
|
2000 |
Brooun A, Liu S, Lewis K. A dose-response study of antibiotic resistance in Pseudomonas aeruginosa biofilms. Antimicrobial Agents and Chemotherapy. 44: 640-6. PMID 10681331 DOI: 10.1128/Aac.44.3.640-646.2000 |
0.471 |
|
2000 |
Stermitz FR, Lorenz P, Tawara JN, Zenewicz LA, Lewis K. Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 97: 1433-7. PMID 10677479 DOI: 10.1073/Pnas.030540597 |
0.424 |
|
2000 |
Arredondo AR, Dorval BL, Klibanov AM, Lewis K. Rapid immunodetection of Escherichia coli Biotechnology Letters. 22: 547-550. DOI: 10.1023/A:1005616523897 |
0.309 |
|
1999 |
Lewis K. Multidrug resistance: Versatile drug sensors of bacterial cells Current Biology. 9. PMID 10359693 DOI: 10.1016/S0960-9822(99)80254-1 |
0.338 |
|
1998 |
Lewis K. Pathogen resistance as the origin of kin altruism Journal of Theoretical Biology. 193: 359-363. PMID 9714935 DOI: 10.1006/Jtbi.1998.0725 |
0.407 |
|
1998 |
Hsieh PC, Siegel SA, Rogers B, Davis D, Lewis K. Bacteria lacking a multidrug pump: a sensitive tool for drug discovery. Proceedings of the National Academy of Sciences of the United States of America. 95: 6602-6. PMID 9618458 DOI: 10.1073/Pnas.95.12.6602 |
0.406 |
|
1997 |
Zhang Y, Lewis K. Fabatins: new antimicrobial plant peptides. Fems Microbiology Letters. 149: 59-64. PMID 9103978 DOI: 10.1111/J.1574-6968.1997.Tb10308.X |
0.301 |
|
1995 |
Ferrante AA, Augliera J, Lewis K, Klibanov AM. Cloning of an organic solvent-resistance gene in Escherichia coli: The unexpected role of alkylhydroperoxide reductase Proceedings of the National Academy of Sciences of the United States of America. 92: 7617-7621. PMID 7644465 DOI: 10.1073/Pnas.92.17.7617 |
0.386 |
|
1994 |
Lewis K. Multidrug resistance pumps in bacteria: variations on a theme Trends in Biochemical Sciences. 19: 119-123. PMID 8203018 DOI: 10.1016/0968-0004(94)90204-6 |
0.406 |
|
1994 |
Lewis K, Naroditskaya V, Ferrante A, Fokina I. Bacterial Resistance To Uncouplers Journal of Bioenergetics and Biomembranes. 26: 639-646. PMID 7721726 DOI: 10.1007/Bf00831539 |
0.4 |
|
1992 |
Lomovskaya O, Lewis K. Emr, an Escherichia coli locus for multidrug resistance. Proceedings of the National Academy of Sciences of the United States of America. 89: 8938-42. PMID 1409590 DOI: 10.1073/Pnas.89.19.8938 |
0.391 |
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