| Year |
Citation |
Score |
| 2020 |
Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, et al. Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217. The Journal of Clinical Investigation. PMID 32721948 DOI: 10.1172/Jci129249 |
0.364 |
|
| 2018 |
Tomko LA, Hill RC, Barrett A, Szulczewski JM, Conklin MW, Eliceiri KW, Keely PJ, Hansen KC, Ponik SM. Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma. Scientific Reports. 8: 12941. PMID 30154546 DOI: 10.1038/S41598-018-31126-W |
0.425 |
|
| 2018 |
Esbona K, Yi Y, Saha S, Yu M, Van Doorn RR, Conklin MW, Graham DS, Wisinski KB, Ponik SM, Eliceiri KW, Wilke LG, Keely PJ. The Presence of Cyclooxygenase 2, Tumor-Associated Macrophages, and Collagen Alignment as Prognostic Markers for Invasive Breast Carcinoma Patients. The American Journal of Pathology. PMID 29429545 DOI: 10.1016/J.Ajpath.2017.10.025 |
0.348 |
|
| 2018 |
Pinkert MA, Salkowski LR, Keely PJ, Hall TJ, Block WF, Eliceiri KW. Review of quantitative multiscale imaging of breast cancer. Journal of Medical Imaging (Bellingham, Wash.). 5: 010901. PMID 29392158 DOI: 10.1117/1.Jmi.5.1.010901 |
0.311 |
|
| 2017 |
Conklin MW, Gangnon RE, Sprague BL, van Germert L, Hampton JM, Eliceiri KW, Bredfeldt JS, Liu Y, Surachaicharn N, Newcomb PA, Friedl A, Keely P, Trentham-Dietz A. Collagen alignment as a predictor of recurrence after ductal carcinoma in situ. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 29141852 DOI: 10.1158/1055-9965.Epi-17-0720 |
0.386 |
|
| 2017 |
Ishihara S, Inman DR, Li WJ, Ponik SM, Keely P. Mechano-signal transduction in mesenchymal stem cells induces prosaposin secretion to drive the proliferation of breast cancer cells. Cancer Research. PMID 28972074 DOI: 10.1158/0008-5472.Can-17-0569 |
0.46 |
|
| 2017 |
Barcus CE, O'Leary KA, Brockman JL, Rugowski DE, Liu Y, Garcia N, Yu M, Keely PJ, Eliceiri KW, Schuler LA. Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells. Breast Cancer Research : Bcr. 19: 9. PMID 28103936 DOI: 10.1186/S13058-017-0801-1 |
0.427 |
|
| 2017 |
Ishihara S, Inman DR, Li W, Ponik SM, Keely PJ. Abstract 5904: Stiffness of extracellular matrix regulates breast cancer progression by stimulating mesenchymal stem cells Cancer Research. 77: 5904-5904. DOI: 10.1158/1538-7445.Am2017-5904 |
0.426 |
|
| 2016 |
Morris BA, Burkel B, Ponik SM, Fan J, Condeelis JS, Aguire-Ghiso JA, Castracane J, Denu JM, Keely PJ. Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells. Ebiomedicine. PMID 27743905 DOI: 10.1016/J.Ebiom.2016.10.012 |
0.405 |
|
| 2016 |
Langevin HM, Keely P, Mao J, Hodge LM, Schleip R, Deng G, Hinz B, Swartz MA, de Valois BA, Zick S, Findley T. Connecting (T)issues: How Research in Fascia Biology Can Impact Integrative Oncology. Cancer Research. PMID 27729327 DOI: 10.1158/0008-5472.Can-16-0753 |
0.313 |
|
| 2016 |
Barcus CE, Keely PJ, Eliceiri KW, Schuler LA. Prolactin signaling through focal adhesion complexes is amplified by stiff extracellular matrices in breast cancer cells. Oncotarget. PMID 27344177 DOI: 10.18632/Oncotarget.10137 |
0.447 |
|
| 2016 |
Corsa CA, Brenot A, Grither WR, Van Hove S, Loza AJ, Zhang K, Ponik SM, Liu Y, DeNardo DG, Eliceiri KW, Keely PJ, Longmore GD. The Action of Discoidin Domain Receptor 2 in Basal Tumor Cells and Stromal Cancer-Associated Fibroblasts Is Critical for Breast Cancer Metastasis. Cell Reports. PMID 27264173 DOI: 10.1016/J.Celrep.2016.05.033 |
0.41 |
|
| 2016 |
Szulczewski JM, Inman DR, Entenberg D, Ponik SM, Aguirre-Ghiso J, Castracane J, Condeelis J, Eliceiri KW, Keely PJ. In Vivo Visualization of Stromal Macrophages via label-free FLIM-based metabolite imaging. Scientific Reports. 6: 25086. PMID 27220760 DOI: 10.1038/Srep25086 |
0.364 |
|
| 2016 |
Burkel B, Morris BA, Ponik SM, Riching KM, Eliceiri KW, Keely PJ. Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo. Journal of Visualized Experiments : Jove. PMID 27213771 DOI: 10.3791/53989 |
0.785 |
|
| 2016 |
García-Mendoza MG, Inman DR, Ponik SM, Jeffery JJ, Sheerar DS, Van Doorn RR, Keely PJ. Neutrophils drive accelerated tumor progression in the collagen-dense mammary tumor microenvironment. Breast Cancer Research : Bcr. 18: 49. PMID 27169366 DOI: 10.1186/S13058-016-0703-7 |
0.408 |
|
| 2016 |
Zhang K, Grither WR, Van Hove S, Biswas H, Ponik SM, Eliceiri KW, Keely PJ, Longmore GD. Mechanical signals regulate and activate SNAIL1 protein to control the fibrogenic response of CAFs. Journal of Cell Science. PMID 27076520 DOI: 10.1242/Jcs.180539 |
0.45 |
|
| 2016 |
Esbona K, Inman D, Saha S, Jeffery J, Schedin P, Wilke L, Keely P. COX-2 modulates mammary tumor progression in response to collagen density. Breast Cancer Research : Bcr. 18: 35. PMID 27000374 DOI: 10.1186/S13058-016-0695-3 |
0.37 |
|
| 2016 |
Le LT, Cazares O, Mouw JK, Chatterjee S, Macias H, Moran A, Ramos J, Keely PJ, Weaver VM, Hinck L. Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness. The Journal of Cell Biology. 212: 707-19. PMID 26975850 DOI: 10.1083/Jcb.201507054 |
0.475 |
|
| 2016 |
Takabatake Y, Oxvig C, Nagi C, Adelson K, Jaffer S, Schmidt H, Keely PJ, Eliceiri KW, Mandeli J, Germain D. Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer. Embo Molecular Medicine. PMID 26951623 DOI: 10.15252/Emmm.201606273 |
0.324 |
|
| 2016 |
Oudin MJ, Jonas O, Kosciuk T, Broye LC, Guido BC, Wyckoff J, Riquelme D, Lamar JM, Asokan SB, Whittaker C, Ma D, Langer R, Cima MJ, Wisinski KB, Hynes RO, ... ... Keely PJ, et al. Tumor cell-driven extracellular matrix remodeling enables haptotaxis during metastatic progression. Cancer Discovery. PMID 26811325 DOI: 10.1158/2159-8290.Cd-15-1183 |
0.463 |
|
| 2016 |
Oudin MJ, Jonas O, Kosciuk T, Broye L, Wyckoff J, Klazen J, Lamar J, Asokan S, Whittaker C, Langer R, Cima M, Wisinski K, Hynes R, Lauffenburger D, Keely P, et al. Abstract PR15: Haptotaxis and direct remodeling of the extracellular matrix by tumor cells is important for metastasis Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-Pr15 |
0.481 |
|
| 2016 |
Mendoza MGG, Inman DR, Jeffery JJ, Keely PJ. Abstract C09: The collagen-dense tumor microenvironment recruits tumor promoting Ly6G+Ly6C+ neutrophils in mouse mammary carcinoma Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-C09 |
0.402 |
|
| 2016 |
Fluegen G, Avivar-Valderas A, Wang Y, Padgen MR, Williams JK, Verkhusha VV, Entenberg D, Eliceiri KW, Castracane J, Keely PJ, Condeelis JS, Aguirre-Ghiso JA. Abstract 4394: Phenotypic heterogeneity of disseminated tumor cells is predetermined by primary tumor hypoxic microenvironments Cancer Research. 76: 4394-4394. DOI: 10.1158/1538-7445.Am2016-4394 |
0.392 |
|
| 2016 |
Esbona K, Saha S, Yi Y, Yu M, Wisinski K, Wilke LG, Keely PJ. Abstract 3927: The presence of COX-2 and tumor-associated macrophages as a prognostic marker for invasive breast carcinoma patients Cancer Research. 76: 3927-3927. DOI: 10.1158/1538-7445.Am2016-3927 |
0.336 |
|
| 2016 |
Butt L, Entenberg D, Hemachandra LPM, Strohmayer M, Keely P, Aguirre-Ghiso J, Condeelis JS, Castracane J. Development of microfluidic-based cell collection devices for in vitro and in vivo use Proceedings of Spie. 9705. DOI: 10.1117/12.2213316 |
0.343 |
|
| 2015 |
Keely P, Nain A. Capturing relevant extracellular matrices for investigating cell migration. F1000research. 4. PMID 26918156 DOI: 10.12688/F1000Research.6623.1 |
0.415 |
|
| 2015 |
Barcus CE, Holt EC, Keely PJ, Eliceiri KW, Schuler LA. Dense collagen-I matrices enhance pro-tumorigenic estrogen-prolactin crosstalk in MCF-7 and T47D breast cancer cells. Plos One. 10: e0116891. PMID 25607819 DOI: 10.1371/Journal.Pone.0116891 |
0.399 |
|
| 2015 |
Tung JC, Barnes JM, Desai SR, Sistrunk C, Conklin MW, Schedin P, Eliceiri KW, Keely PJ, Seewaldt VL, Weaver VM. Tumor mechanics and metabolic dysfunction. Free Radical Biology & Medicine. 79: 269-80. PMID 25532934 DOI: 10.1016/J.Freeradbiomed.2014.11.020 |
0.368 |
|
| 2015 |
Curran CS, Carrillo ER, Ponik SM, Keely PJ. Collagen density regulates xenobiotic and hypoxic response of mammary epithelial cells. Environmental Toxicology and Pharmacology. 39: 114-24. PMID 25481308 DOI: 10.1016/J.Etap.2014.10.017 |
0.399 |
|
| 2015 |
Riching KM, Keely PJ. Rho family GTPases: making it to the third dimension. The International Journal of Biochemistry & Cell Biology. 59: 111-5. PMID 25478651 DOI: 10.1016/J.Biocel.2014.11.007 |
0.756 |
|
| 2015 |
Barcus CE, Holt EC, Keely PJ, Eliceiri KW, Schuler LA. E2+PRL induces invasion only in high density/ stiff collagen matrices. Plos One. DOI: 10.1371/Journal.Pone.0116891.G007 |
0.32 |
|
| 2015 |
Barcus CE, Holt EC, Keely PJ, Eliceiri KW, Schuler LA. SFKs mediate PRL-augmented growth only in high density/ stiff collagen matrices. Plos One. DOI: 10.1371/Journal.Pone.0116891.G006 |
0.307 |
|
| 2015 |
Barcus CE, Holt EC, Keely PJ, Eliceiri KW, Schuler LA. JAK2 mediates PRL-driven growth regardless of matrix density. Plos One. DOI: 10.1371/Journal.Pone.0116891.G005 |
0.313 |
|
| 2015 |
Barcus CE, Holt EC, Keely PJ, Eliceiri KW, Schuler LA. High density/ stiff collagen matrices enhance E2 and PRL induced cell growth, and inhibit apoptosis in T47D cells. Plos One. DOI: 10.1371/Journal.Pone.0116891.G004 |
0.358 |
|
| 2015 |
Barcus CE, Holt EC, Keely PJ, Eliceiri KW, Schuler LA. Matrix density alters E2-induced changes in transcripts in MCF-7 and T47D cells in a cell-context dependent manner. Plos One. DOI: 10.1371/Journal.Pone.0116891.G002 |
0.395 |
|
| 2015 |
Burkel B, Ponik S, Morris B, Eliceiri K, Keely P. Abstract B02: Matrix stiffness regulates local metabolism of breast carcinoma cells Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-B02 |
0.481 |
|
| 2015 |
Morris BA, Burkel B, Ponik S, Eliceiri K, Aguirre-Ghiso J, Condeelis J, Castracane J, Keely PJ. Abstract 332: Extracellular matrix stiffness regulates metabolic state in metastatic, but not quiescent, breast carcinoma cells Cancer Research. 75: 332-332. DOI: 10.1158/1538-7445.Am2015-332 |
0.479 |
|
| 2015 |
Mendoza MGG, Inman D, Ponik SM, Keely PJ. Abstract 2345: The collagen-dense tumor microenvironment increases neutrophil recruitment in mouse mammary carcinoma Cancer Research. 75: 2345-2345. DOI: 10.1158/1538-7445.Am2015-2345 |
0.442 |
|
| 2015 |
Sanders JM, Butt L, Clark A, Williams J, Padgen M, Leung E, Keely P, Condeelis JS, Aguirre-Ghiso J, Castracane J. A bioMEMS device for the study of mechanical properties of cells Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9320. DOI: 10.1117/12.2078521 |
0.384 |
|
| 2014 |
Riching KM, Cox BL, Salick MR, Pehlke C, Riching AS, Ponik SM, Bass BR, Crone WC, Jiang Y, Weaver AM, Eliceiri KW, Keely PJ. 3D collagen alignment limits protrusions to enhance breast cancer cell persistence. Biophysical Journal. 107: 2546-58. PMID 25468334 DOI: 10.1016/J.Bpj.2014.10.035 |
0.793 |
|
| 2014 |
Lee B, Zhou X, Riching K, Eliceiri KW, Keely PJ, Guelcher SA, Weaver AM, Jiang Y. A three-dimensional computational model of collagen network mechanics. Plos One. 9: e111896. PMID 25386649 DOI: 10.1371/Journal.Pone.0111896 |
0.743 |
|
| 2014 |
Bredfeldt JS, Liu Y, Conklin MW, Keely PJ, Mackie TR, Eliceiri KW. Automated quantification of aligned collagen for human breast carcinoma prognosis. Journal of Pathology Informatics. 5: 28. PMID 25250186 DOI: 10.4103/2153-3539.139707 |
0.441 |
|
| 2014 |
Bischel LL, Sung KE, Jiménez-Torres JA, Mader B, Keely PJ, Beebe DJ. The importance of being a lumen. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4583-90. PMID 25077562 DOI: 10.1096/Fj.13-243733 |
0.323 |
|
| 2014 |
Karta MR, Gavala ML, Curran CS, Wickert LE, Keely PJ, Gern JE, Bertics PJ. LPS modulates rhinovirus-induced chemokine secretion in monocytes and macrophages. American Journal of Respiratory Cell and Molecular Biology. 51: 125-34. PMID 24498897 DOI: 10.1165/Rcmb.2013-0404Oc |
0.749 |
|
| 2014 |
Bredfeldt JS, Liu Y, Pehlke CA, Conklin MW, Szulczewski JM, Inman DR, Keely PJ, Nowak RD, Mackie TR, Eliceiri KW. Computational segmentation of collagen fibers from second-harmonic generation images of breast cancer. Journal of Biomedical Optics. 19: 16007. PMID 24407500 DOI: 10.1117/1.Jbo.19.1.016007 |
0.327 |
|
| 2014 |
Lee B, Zhou X, Riching K, Eliceiri KW, Keely PJ, Guelcher SA, Weaver AM, Jiang Y. Parameters for elastic collagen fiber network simulations. Plos One. DOI: 10.1371/Journal.Pone.0111896.T001 |
0.683 |
|
| 2014 |
Keely PJ. Abstract SY21-02: Extracellular matrix density, alignment, and tumor progression Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy21-02 |
0.457 |
|
| 2014 |
Esbona K, Inman D, Saha S, Eliceiri K, Wilke LG, Keely PJ. Abstract 1116: Response to cyclooxygenase-2 inhibition is regulated by collagen dense stroma Cancer Research. 74: 1116-1116. DOI: 10.1158/1538-7445.Am2014-1116 |
0.41 |
|
| 2014 |
Bredfeldt J, Liu Y, Conklin M, Keely P, Eliceiri K, Mackie T. SU-E-J-107: Supervised Learning Model of Aligned Collagen for Human Breast Carcinoma Prognosis Medical Physics. 41: 180-180. DOI: 10.1118/1.4888159 |
0.406 |
|
| 2013 |
Bredfeldt J, Liu Y, Wilke L, Keely P, Mackie T, Eliceiri K. MO-D-141-08: Multi-Scale Analysis of Collagen Architecture for Classifying Tumor and Healthy Breast Tissue Images. Medical Physics. 40: 400-401. PMID 28518438 DOI: 10.1118/1.4815255 |
0.353 |
|
| 2013 |
Keely PJ. Proteolytic remodeling of the ECM and the geometric control of stem cell fate. Developmental Cell. 25: 325-6. PMID 23725758 DOI: 10.1016/J.Devcel.2013.05.012 |
0.364 |
|
| 2013 |
Zhang K, Corsa CA, Ponik SM, Prior JL, Piwnica-Worms D, Eliceiri KW, Keely PJ, Longmore GD. The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis. Nature Cell Biology. 15: 677-87. PMID 23644467 DOI: 10.1038/Ncb2743 |
0.399 |
|
| 2013 |
Gehler S, Ponik SM, Riching KM, Keely PJ. Bi-directional signaling: extracellular matrix and integrin regulation of breast tumor progression. Critical Reviews in Eukaryotic Gene Expression. 23: 139-57. PMID 23582036 DOI: 10.1615/Critreveukargeneexpr.2013006647 |
0.799 |
|
| 2013 |
Ponik SM, Trier SM, Wozniak MA, Eliceiri KW, Keely PJ. RhoA is down-regulated at cell-cell contacts via p190RhoGAP-B in response to tensional homeostasis. Molecular Biology of the Cell. 24: 1688-99, S1-3. PMID 23552690 DOI: 10.1091/Mbc.E12-05-0386 |
0.798 |
|
| 2013 |
Barcus CE, Keely PJ, Eliceiri KW, Schuler LA. Stiff collagen matrices increase tumorigenic prolactin signaling in breast cancer cells. The Journal of Biological Chemistry. 288: 12722-32. PMID 23530035 DOI: 10.1074/Jbc.M112.447631 |
0.463 |
|
| 2013 |
Curran CS, Keely PJ. Breast tumor and stromal cell responses to TGF-β and hypoxia in matrix deposition. Matrix Biology : Journal of the International Society For Matrix Biology. 32: 95-105. PMID 23262216 DOI: 10.1016/J.Matbio.2012.11.016 |
0.442 |
|
| 2013 |
Clark AN, Williams J, Padgen M, Keely P, Castracane J. Abstract A082: Study of the effects of localized collagen manipulation on the behavior of breast cancer cells Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-A082 |
0.45 |
|
| 2013 |
Chute CL, Keely P, Alexander C, Friedl A. Abstract B71: Syndecan-1 promotes breast cancer metastasis by modulating tissue stiffness Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-B71 |
0.41 |
|
| 2013 |
Esbona K, Inman DR, Eliceiri KW, Wilke LG, Keely PJ. Abstract 4960: COX-2 inhibition with celecoxib delays the progression of invasive mammary carcinoma in a murine model of collagen dense stroma. Cancer Research. 73: 4960-4960. DOI: 10.1158/1538-7445.Am2013-4960 |
0.418 |
|
| 2013 |
Trentham-Dietz A, Conklin M, Gangnon R, Sprague B, Eliceiri K, Bredfeldt J, Surachaicharn N, Campagnola P, Friedl A, Newcomb P, Keely P. Abstract P1-06-06: Alteration of stromal collagen fiber orientation in DCIS Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P1-06-06 |
0.378 |
|
| 2013 |
Esbona K, Inman D, Eliceiri K, Wilke L, Keely P. Abstract P1-06-02: Inflammatory stromal cell response induced by collagen dense stroma is regulated by cyclooxygenase-2 in a mouse breast cancer model Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P1-06-02 |
0.408 |
|
| 2013 |
Clark A, Williams J, Padgen M, Keely P, Condeelis J, Castracane J. Optimized release matrices for use in a BioMEMS device to study metastasis Proceedings of Spie - the International Society For Optical Engineering. 8615. DOI: 10.1117/12.2005048 |
0.335 |
|
| 2012 |
Heck JN, Ponik SM, Garcia-Mendoza MG, Pehlke CA, Inman DR, Eliceiri KW, Keely PJ. Microtubules regulate GEF-H1 in response to extracellular matrix stiffness. Molecular Biology of the Cell. 23: 2583-92. PMID 22593214 DOI: 10.1091/Mbc.E11-10-0876 |
0.794 |
|
| 2012 |
Conklin MW, Keely PJ. Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers. Cell Adhesion & Migration. 6: 249-60. PMID 22568982 DOI: 10.4161/Cam.20567 |
0.39 |
|
| 2012 |
Bragado P, Sosa MS, Keely P, Condeelis J, Aguirre-Ghiso JA. Microenvironments dictating tumor cell dormancy. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrã¨S Dans Les Recherches Sur Le Cancer. 195: 25-39. PMID 22527492 DOI: 10.1007/978-3-642-28160-0_3 |
0.362 |
|
| 2012 |
Campagnola PJ, Brewer MA, Tilbury K, Ajeti V, Eliceiri KE, Keely PJ, Patankar M. SHG imaging of cancer Biomedical Optics, Biomed 2012. DOI: 10.1364/Biomed.2012.Bsu4B.1 |
0.332 |
|
| 2012 |
Young PA, Nazir M, Szulczewski MJ, Keely PJ, Eliceiri KW. Second-harmonic generation and fluorescence lifetime imaging microscopy through a rodent mammary imaging window Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8226. DOI: 10.1117/12.906409 |
0.395 |
|
| 2011 |
Borges VF, Lyons T, O'Brien J, Russell T, Martinson H, Keely P, Schedin PJ. The role of collagen and COX-2 in post-partum breast involution on the progression of pregnancy-associated breast cancer and its inhibition by NSAIDs. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e11117. PMID 28023829 DOI: 10.1200/Jco.2011.29.15_Suppl.E11117 |
0.329 |
|
| 2011 |
Ajeti V, Nadiarnykh O, Ponik SM, Keely PJ, Eliceiri KW, Campagnola PJ. Structural changes in mixed Col I/Col V collagen gels probed by SHG microscopy: implications for probing stromal alterations in human breast cancer. Biomedical Optics Express. 2: 2307-16. PMID 21833367 DOI: 10.1364/Boe.2.002307 |
0.375 |
|
| 2011 |
Keely PJ. Mechanisms by which the extracellular matrix and integrin signaling act to regulate the switch between tumor suppression and tumor promotion. Journal of Mammary Gland Biology and Neoplasia. 16: 205-19. PMID 21822945 DOI: 10.1007/S10911-011-9226-0 |
0.509 |
|
| 2011 |
Lyons TR, O'Brien J, Borges VF, Conklin MW, Keely PJ, Eliceiri KW, Marusyk A, Tan AC, Schedin P. Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. Nature Medicine. 17: 1109-15. PMID 21822285 DOI: 10.1038/Nm.2416 |
0.368 |
|
| 2011 |
Goetz JG, Minguet S, Navarro-Lérida I, Lazcano JJ, Samaniego R, Calvo E, Tello M, Osteso-Ibáñez T, Pellinen T, Echarri A, Cerezo A, Klein-Szanto AJ, Garcia R, Keely PJ, Sánchez-Mateos P, et al. Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis. Cell. 146: 148-63. PMID 21729786 DOI: 10.1016/j.cell.2011.05.040 |
0.344 |
|
| 2011 |
Provenzano PP, Keely PJ. Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling. Journal of Cell Science. 124: 1195-205. PMID 21444750 DOI: 10.1242/Jcs.067009 |
0.485 |
|
| 2011 |
Conklin MW, Eickhoff JC, Riching KM, Pehlke CA, Eliceiri KW, Provenzano PP, Friedl A, Keely PJ. Aligned collagen is a prognostic signature for survival in human breast carcinoma. The American Journal of Pathology. 178: 1221-32. PMID 21356373 DOI: 10.1016/J.Ajpath.2010.11.076 |
0.718 |
|
| 2011 |
Schedin P, Keely PJ. Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression. Cold Spring Harbor Perspectives in Biology. 3: a003228. PMID 20980442 DOI: 10.1101/Cshperspect.A003228 |
0.478 |
|
| 2011 |
Lyons TR, O'Brien J, Conklin M, Keely P, Borges V, Schedin P. Abstract B61: Postpartum mammary gland involution drives DCIS progression through collagen and COX-2, identifying a target for intervention Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-B61 |
0.366 |
|
| 2011 |
Conklin MW, Eickhoff J, Riching K, Pehlke C, Eliceiri K, Provenzano P, Friedl A, Keely PJ. Abstract A35: Aligned collagen is a prognostic signature for survival in human breast carcinoma Cancer Research. 73: 4749-4749. DOI: 10.1158/1538-7445.Tim2013-A35 |
0.746 |
|
| 2011 |
Schedin P, Lyons T, O'Brien J, Callihan E, Russell T, Martinson H, Tan A, Hansen K, Keely P, Borges V. BS3-2: Mammary Stroma as an NSAID Target; Implications for Pregnancy-Associated Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-Bs3-2 |
0.385 |
|
| 2010 |
Provenzano PP, Eliceiri KW, Inman DR, Keely PJ. Engineering three-dimensional collagen matrices to provide contact guidance during 3D cell migration. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 10.17. PMID 20521230 DOI: 10.1002/0471143030.Cb1017S47 |
0.483 |
|
| 2010 |
Conklin MW, Ada-Nguema A, Parsons M, Riching KM, Keely PJ. R-Ras regulates beta1-integrin trafficking via effects on membrane ruffling and endocytosis. Bmc Cell Biology. 11: 14. PMID 20167113 DOI: 10.1186/1471-2121-11-14 |
0.757 |
|
| 2010 |
Schedin P, Lyons TR, O'Brien J, Maller O, Keely PJ, Conklin MW, Borges V. Abstract CN10-03: Stromal signals from the involuting microenvironment that are important in postpartum breast cancer Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-Cn10-03 |
0.375 |
|
| 2010 |
Jessica HN, Ponik SM, Provenzano PP, Keely PJ. Abstract LB-239: The Rho GEF, GEF-H1, is regulated by and activates Rho in response to 3-D collagen matrix density in breast epithelial cells Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-239 |
0.502 |
|
| 2010 |
Suzanne P, Wozniak M, Keely PJ. Abstract LB-231: p 190RhoGAP-B is required for rho down-regulation and ductal morphogenesis of breast epithelial cells in compliant collagen gels Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-231 |
0.479 |
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| 2009 |
Provenzano PP, Inman DR, Eliceiri KW, Keely PJ. Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage. Oncogene. 28: 4326-43. PMID 19826415 DOI: 10.1038/Onc.2009.299 |
0.507 |
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| 2009 |
Provenzano PP, Eliceiri KW, Keely PJ. Shining new light on 3D cell motility and the metastatic process. Trends in Cell Biology. 19: 638-48. PMID 19819146 DOI: 10.1016/J.Tcb.2009.08.009 |
0.409 |
|
| 2009 |
Provenzano PP, Keely PJ. The role of focal adhesion kinase in tumor initiation and progression. Cell Adhesion & Migration. 3: 347-50. PMID 19690467 DOI: 10.4161/Cam.3.4.9458 |
0.411 |
|
| 2009 |
Sung KE, Su G, Pehlke C, Trier SM, Eliceiri KW, Keely PJ, Friedl A, Beebe DJ. Control of 3-dimensional collagen matrix polymerization for reproducible human mammary fibroblast cell culture in microfluidic devices. Biomaterials. 30: 4833-41. PMID 19540580 DOI: 10.1016/J.Biomaterials.2009.05.043 |
0.801 |
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| 2009 |
Gehler S, Baldassarre M, Lad Y, Leight JL, Wozniak MA, Riching KM, Eliceiri KW, Weaver VM, Calderwood DA, Keely PJ. Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension. Molecular Biology of the Cell. 20: 3224-38. PMID 19458194 DOI: 10.1091/Mbc.E08-12-1186 |
0.785 |
|
| 2009 |
Conklin MW, Provenzano PP, Eliceiri KW, Sullivan R, Keely PJ. Fluorescence lifetime imaging of endogenous fluorophores in histopathology sections reveals differences between normal and tumor epithelium in carcinoma in situ of the breast. Cell Biochemistry and Biophysics. 53: 145-57. PMID 19259625 DOI: 10.1007/S12013-009-9046-7 |
0.31 |
|
| 2009 |
Provenzano PP, Eliceiri KW, Keely PJ. Multiphoton microscopy and fluorescence lifetime imaging microscopy (FLIM) to monitor metastasis and the tumor microenvironment. Clinical & Experimental Metastasis. 26: 357-70. PMID 18766302 DOI: 10.1007/S10585-008-9204-0 |
0.401 |
|
| 2008 |
Provenzano PP, Eliceiri KW, Yan L, Ada-Nguema A, Conklin MW, Inman DR, Keely PJ. Nonlinear optical imaging of cellular processes in breast cancer. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 14: 532-48. PMID 18986607 DOI: 10.1017/S1431927608080884 |
0.769 |
|
| 2008 |
Provenzano PP, Inman DR, Eliceiri KW, Beggs HE, Keely PJ. Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer. The American Journal of Pathology. 173: 1551-65. PMID 18845837 DOI: 10.2353/Ajpath.2008.080308 |
0.412 |
|
| 2008 |
Provenzano PP, Inman DR, Eliceiri KW, Trier SM, Keely PJ. Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization. Biophysical Journal. 95: 5374-84. PMID 18775961 DOI: 10.1529/Biophysj.108.133116 |
0.818 |
|
| 2008 |
Provenzano PP, Rueden CT, Trier SM, Yan L, Ponik SM, Inman DR, Keely PJ, Eliceiri KW. Nonlinear optical imaging and spectral-lifetime computational analysis of endogenous and exogenous fluorophores in breast cancer. Journal of Biomedical Optics. 13: 031220. PMID 18601544 DOI: 10.1117/1.2940365 |
0.774 |
|
| 2008 |
Provenzano PP, Inman DR, Eliceiri KW, Knittel JG, Yan L, Rueden CT, White JG, Keely PJ. Collagen density promotes mammary tumor initiation and progression. Bmc Medicine. 6: 11. PMID 18442412 DOI: 10.1186/1741-7015-6-11 |
0.432 |
|
| 2008 |
Keely PJ. Cell Matrix Adhesion in Three Dimensions Cell Junctions: Adhesion, Development, and Disease. 135-149. DOI: 10.1002/9783527622092.ch7 |
0.332 |
|
| 2007 |
Keely PJ, Conklin MW, Gehler S, Ponik SM, Provenzano PP. Investigating integrin regulation and signaling events in three-dimensional systems. Methods in Enzymology. 426: 27-45. PMID 17697878 DOI: 10.1016/S0076-6879(07)26002-1 |
0.782 |
|
| 2007 |
Skala MC, Riching KM, Bird DK, Gendron-Fitzpatrick A, Eickhoff J, Eliceiri KW, Keely PJ, Ramanujam N. In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia. Journal of Biomedical Optics. 12: 024014. PMID 17477729 DOI: 10.1117/1.2717503 |
0.713 |
|
| 2006 |
Provenzano PP, Eliceiri KW, Campbell JM, Inman DR, White JG, Keely PJ. Collagen reorganization at the tumor-stromal interface facilitates local invasion. Bmc Medicine. 4: 38. PMID 17190588 DOI: 10.1186/1741-7015-4-38 |
0.417 |
|
| 2006 |
Modzelewska K, Newman LP, Desai R, Keely PJ. Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas. The Journal of Biological Chemistry. 281: 37527-35. PMID 17038317 DOI: 10.1074/Jbc.M604342200 |
0.767 |
|
| 2006 |
Pal S, Wu J, Murray JK, Gellman SH, Wozniak MA, Keely PJ, Boyer ME, Gomez TM, Hasso SM, Fallon JF, Bresnick EH. An antiangiogenic neurokinin-B/thromboxane A2 regulatory axis. The Journal of Cell Biology. 174: 1047-58. PMID 17000881 DOI: 10.1083/Jcb.200603152 |
0.718 |
|
| 2006 |
Ada-Nguema AS, Xenias H, Hofman JM, Wiggins CH, Sheetz MP, Keely PJ. The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCepsilon. Journal of Cell Science. 119: 1307-19. PMID 16537651 DOI: 10.1242/Jcs.02835 |
0.775 |
|
| 2006 |
Ada-Nguema AS, Xenias H, Hofman JM, Wiggins CH, Sheetz M, Keely PJ. Erratum: The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCε (J. Cell Sci. vol. 119 (1307-1319)) Journal of Cell Science. 119. DOI: 10.1242/Jcs.03260 |
0.779 |
|
| 2006 |
Pal S, Wu J, Murray JK, Gellman SH, Wozniak MA, Keely PJ, Boyer ME, Gomez TM, Hasso SM, Fallon JF, Bresnick EH. Correction: Ubp6 delays destruction Journal of Cell Biology. 175: 671-671. DOI: 10.1083/Jcb.20060315220061030C |
0.565 |
|
| 2005 |
Wozniak MA, Keely PJ. Use of three-dimensional collagen gels to study mechanotransduction in T47D breast epithelial cells. Biological Procedures Online. 7: 144-61. PMID 16299584 DOI: 10.1251/Bpo112 |
0.705 |
|
| 2005 |
Wozniak MA, Kwong L, Chodniewicz D, Klemke RL, Keely PJ. R-Ras controls membrane protrusion and cell migration through the spatial regulation of Rac and Rho. Molecular Biology of the Cell. 16: 84-96. PMID 15525681 DOI: 10.1091/Mbc.E04-04-0277 |
0.78 |
|
| 2004 |
Wozniak MA, Modzelewska K, Kwong L, Keely PJ. Focal adhesion regulation of cell behavior. Biochimica Et Biophysica Acta. 1692: 103-19. PMID 15246682 DOI: 10.1016/J.Bbamcr.2004.04.007 |
0.793 |
|
| 2003 |
Palmer GM, Keely PJ, Breslin TM, Ramanujam N. Autofluorescence spectroscopy of normal and malignant human breast cell lines. Photochemistry and Photobiology. 78: 462-9. PMID 14653577 DOI: 10.1562/0031-8655(2003)078<0462:Asonam>2.0.Co;2 |
0.357 |
|
| 2003 |
Wozniak MA, Desai R, Solski PA, Der CJ, Keely PJ. ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix. The Journal of Cell Biology. 163: 583-95. PMID 14610060 DOI: 10.1083/Jcb.200305010 |
0.714 |
|
| 2003 |
Kwong L, Wozniak MA, Collins AS, Wilson SD, Keely PJ. R-Ras promotes focal adhesion formation through focal adhesion kinase and p130(Cas) by a novel mechanism that differs from integrins. Molecular and Cellular Biology. 23: 933-49. PMID 12529399 DOI: 10.1128/Mcb.23.3.933-949.2003 |
0.8 |
|
| 2002 |
Gabarra-Niecko V, Keely PJ, Schaller MD. Characterization of an activated mutant of focal adhesion kinase: 'SuperFAK'. The Biochemical Journal. 365: 591-603. PMID 11988069 DOI: 10.1042/Bj20020065 |
0.357 |
|
| 2001 |
Keely PJ. Ras and Rho protein induction of motility and invasion in T47D breast adenocarcinoma cells. Methods in Enzymology. 333: 256-66. PMID 11400341 DOI: 10.1016/S0076-6879(01)33061-6 |
0.441 |
|
| 1999 |
Eisenmann KM, McCarthy JB, Simpson MA, Keely PJ, Guan JL, Tachibana K, Lim L, Manser E, Furcht LT, Iida J. Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas Nature Cell Biology. 1: 507-513. PMID 10587647 DOI: 10.1038/70302 |
0.37 |
|
| 1998 |
Keely P, Parise L, Juliano R. Integrins and GTPases in tumour cell growth, motility and invasion. Trends in Cell Biology. 8: 101-6. PMID 9695818 DOI: 10.1016/S0962-8924(97)01219-1 |
0.301 |
|
| 1995 |
Keely PJ, Fong AM, Zutter MM, Santoro SA. Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of antisense α2 integrin mRNA in mammary cells Journal of Cell Science. 108: 595-607. PMID 7769004 |
0.326 |
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