Christopher R. Jacobs - Publications

Affiliations: 
Biomedical Engineering Columbia University, New York, NY 
Area:
Biomedical Engineering, Cell Biology, Medicine and Surgery

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Chen JC, Hoey DA, Chua M, Bellon R, Jacobs CR. Mechanical signals promote osteogenic fate through a primary cilia-mediated mechanism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26675708 DOI: 10.1096/fj.15-276402  0.88
2015 Duffy MP, Jacobs CR. Seeing the unseen: cell strain and mechanosensing. Biophysical Journal. 108: 1583-4. PMID 25863048 DOI: 10.1016/j.bpj.2015.03.008  0.64
2015 Chen JC, Chua M, Bellon RB, Jacobs CR. Epigenetic changes during mechanically induced osteogenic lineage commitment. Journal of Biomechanical Engineering. 137: 020902. PMID 25581684 DOI: 10.1115/1.4029551  0.64
2014 Espinha LC, Hoey DA, Fernandes PR, Rodrigues HC, Jacobs CR. Oscillatory fluid flow influences primary cilia and microtubule mechanics. Cytoskeleton (Hoboken, N.J.). 71: 435-45. PMID 25044764 DOI: 10.1002/cm.21183  0.88
2014 Lee KL, Hoey DA, Spasic M, Tang T, Hammond HK, Jacobs CR. Adenylyl cyclase 6 mediates loading-induced bone adaptation in vivo Faseb Journal. 28: 1157-1165. PMID 24277577 DOI: 10.1096/fj.13-240432  0.88
2014 Downs ME, Nguyen AM, Herzog FA, Hoey DA, Jacobs CR. An experimental and computational analysis of primary cilia deflection under fluid flow. Computer Methods in Biomechanics and Biomedical Engineering. 17: 2-10. PMID 22452422 DOI: 10.1080/10255842.2011.653784  0.88
2013 Chen JC, Jacobs CR. Mechanically induced osteogenic lineage commitment of stem cells Stem Cell Research and Therapy. 4. PMID 24004875 DOI: 10.1186/scrt318  0.88
2013 Leucht P, Temiyasathit S, Russell A, Arguello JF, Jacobs CR, Helms JA, Castillo AB. CXCR4 antagonism attenuates load-induced periosteal bone formation in mice. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 1828-38. PMID 23881789 DOI: 10.1002/jor.22440  0.88
2013 Nguyen AM, Jacobs CR. Emerging role of primary cilia as mechanosensors in osteocytes. Bone. 54: 196-204. PMID 23201223 DOI: 10.1016/j.bone.2012.11.016  0.88
2013 Leucht P, Monica SD, Temiyasathit S, Lenton K, Manu A, Longaker MT, Jacobs CR, Spilker RL, Guo H, Brunski JB, Helms JA. Primary cilia act as mechanosensors during bone healing around an implant. Medical Engineering & Physics. 35: 392-402. PMID 22784673 DOI: 10.1016/j.medengphy.2012.06.005  0.88
2013 Chen JC, Castillo AB, Jacobs CR. Cellular and Molecular Mechanotransduction in Bone Osteoporosis: Fourth Edition. 453-475. DOI: 10.1016/B978-0-12-415853-5.00020-0  0.88
2012 Brown G, Butler PJ, Chang DW, Chien S, Clegg RM, Dewey CF, Dong C, Guo XE, Helmke BP, Hess H, Jacobs CR, Kaunas RR, Kumar S, Lu HH, Mathur AB, et al. Cellular and Molecular Bioengineering: A Tipping Point. Cellular and Molecular Bioengineering. 5: 239-253. PMID 23264805 DOI: 10.1007/s12195-012-0246-7  0.88
2012 Castillo AB, Blundo JT, Chen JC, Lee KL, Yereddi NR, Jang E, Kumar S, Tang WJ, Zarrin S, Kim JB, Jacobs CR. Focal Adhesion Kinase Plays a Role in Osteoblast Mechanotransduction In Vitro but Does Not Affect Load-Induced Bone Formation In Vivo Plos One. 7. PMID 23028449 DOI: 10.1371/journal.pone.0043291  0.88
2012 Hoey DA, Tormey S, Ramcharan S, O'Brien FJ, Jacobs CR. Primary cilia-mediated mechanotransduction in human mesenchymal stem cells Stem Cells. 30: 2561-2570. PMID 22969057 DOI: 10.1002/stem.1235  0.88
2012 Young YN, Downs M, Jacobs CR. Dynamics of the primary cilium in shear flow Biophysical Journal. 103: 629-639. PMID 22947924 DOI: 10.1016/j.bpj.2012.07.009  0.88
2012 Temiyasathit S, Tang WJ, Leucht P, Anderson CT, Monica SD, Castillo AB, Helms JA, Stearns T, Jacobs CR. Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading. Plos One. 7: e33368. PMID 22428034 DOI: 10.1371/journal.pone.0033368  0.88
2012 Hoey DA, Downs ME, Jacobs CR. The mechanics of the primary cilium: An intricate structure with complex function Journal of Biomechanics. 45: 17-26. PMID 21899847 DOI: 10.1016/j.jbiomech.2011.08.008  0.88
2012 Hoey DA, Chen JC, Jacobs CR. The primary cilium as a novel extracellular sensor in bone Frontiers in Endocrinology. 3. DOI: 10.3389/fendo.2012.00075  0.88
2011 Lee HG, Minematsu H, Kim KO, Celil Aydemir AB, Shin MJ, Nizami SA, Chung KJ, Hsu AC, Jacobs CR, Lee FY. Actin and ERK1/2-CEBPβ signaling mediates phagocytosis-induced innate immune response of osteoprogenitor cells. Biomaterials. 32: 9197-206. PMID 21899882 DOI: 10.1016/j.biomaterials.2011.08.059  0.88
2011 Hoey DA, Kelly DJ, Jacobs CR. A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells Biochemical and Biophysical Research Communications. 412: 182-187. PMID 21810408 DOI: 10.1016/j.bbrc.2011.07.072  0.88
2011 Case N, Sen B, Thomas JA, Styner M, Xie Z, Jacobs CR, Rubin J. Steady and oscillatory fluid flows produce a similar osteogenic phenotype Calcified Tissue International. 88: 189-197. PMID 21165611 DOI: 10.1007/s00223-010-9448-y  0.88
2011 Hoey DA, Jacobs CR. Oscillatory fluid flow affects the osteogenic differentiation of human bone marrow stromal cells in a primary cilium dependent manner Asme 2011 Summer Bioengineering Conference, Sbc 2011. 331-332. DOI: 10.1115/SBC2011-53435  0.88
2011 Jeon OH, Yoo YM, Kim KH, Jacobs CR, Kim CH. Primary cilia-mediated osteogenic response to fluid flow occurs via increases in focal adhesion and akt signaling pathway in MC3T3-E1 osteoblastic cells Cellular and Molecular Bioengineering. 4: 379-388. DOI: 10.1007/s12195-011-0191-x  0.88
2011 Jacobs CR, Kelly DJ. Cell mechanics: The role of simulation Computational Methods in Applied Sciences. 20: 1-14. DOI: 10.1007/978-94-007-1254-6_1  0.64
2011 Herzog FA, Jacobs CR. Effects of mechanical stress on cells Comprehensive Biomaterials. 5: 73-80.  0.88
2010 Tummala P, Arnsdorf EJ, Jacobs CR. The Role of Primary Cilia in Mesenchymal Stem Cell Differentiation: A Pivotal Switch in Guiding Lineage Commitment. Cellular and Molecular Bioengineering. 3: 207-212. PMID 20823950 DOI: 10.1007/s12195-010-0127-x  0.48
2010 Arnsdorf EJ, Tummala P, Castillo AB, Zhang F, Jacobs CR. The epigenetic mechanism of mechanically induced osteogenic differentiation Journal of Biomechanics. 43: 2881-2886. PMID 20728889 DOI: 10.1016/j.jbiomech.2010.07.033  0.88
2010 Jacobs CR, Temiyasathit S, Castillo AB. Osteocyte mechanobiology and pericellular mechanics Annual Review of Biomedical Engineering. 12: 369-400. PMID 20617941 DOI: 10.1146/annurev-bioeng-070909-105302  0.88
2010 Castillo AB, Jacobs CR. Mesenchymal stem cell mechanobiology Current Osteoporosis Reports. 8: 98-104. PMID 20425617 DOI: 10.1007/s11914-010-0015-2  0.64
2010 Temiyasathit S, Jacobs CR. Osteocyte primary cilium and its role in bone mechanotransduction Annals of the New York Academy of Sciences. 1192: 422-428. PMID 20392268 DOI: 10.1111/j.1749-6632.2009.05243.x  0.64
2010 Kwon RY, Temiyasathit S, Tummala P, Quah CC, Jacobs CR. Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells Faseb Journal. 24: 2859-2868. PMID 20371630 DOI: 10.1096/fj.09-148007  0.88
2010 Kelly DJ, Jacobs CR. The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells Birth Defects Research Part C - Embryo Today: Reviews. 90: 75-85. PMID 20301221 DOI: 10.1002/bdrc.20173  0.64
2010 Litzenberger JB, Kim JB, Tummala P, Jacobs CR. β1 Integrins mediate mechanosensitive signaling pathways in Osteocytes Calcified Tissue International. 86: 325-332. PMID 20213106 DOI: 10.1007/s00223-010-9343-6  0.64
2010 Shivaram GM, Kim CH, Batra NN, Yang W, Harris SE, Jacobs CR. Novel early response genes in osteoblasts exposed to dynamic fluid flow. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 368: 605-16. PMID 20047941 DOI: 10.1098/rsta.2009.0231  0.64
2010 Wang L, Shi X, Zhao R, Halloran BP, Clark DJ, Jacobs CR, Kingery WS. Calcitonin-gene-related peptide stimulates stromal cell osteogenic differentiation and inhibits RANKL induced NF-kappaB activation, osteoclastogenesis and bone resorption. Bone. 46: 1369-79. PMID 19962460 DOI: 10.1016/j.bone.2009.11.029  0.64
2010 Herzog FA, Geraedts J, Hoey D, Jacobs CR. A mathematical approach to study the bending behavior of the primary cilium Proceedings of the 2010 Ieee 36th Annual Northeast Bioengineering Conference, Nebec 2010. DOI: 10.1109/NEBC.2010.5458157  0.88
2010 Tummala P, Arnsdorf EJ, Jacobs CR. The role of primary cilia in mesenchymal stem cell differentiation: A pivotal switch in guiding lineage commitment Cellular and Molecular Bioengineering. 3: 207-212. DOI: 10.1007/s12195-010-0127-x  0.88
2010 Lee KL, Hoey DA, Jacobs CR. Primary cilia-mediated mechanotransduction in bone Clinical Reviews in Bone and Mineral Metabolism. 8: 201-212. DOI: 10.1007/s12018-010-9078-y  0.88
2009 Kim CH, Kim KH, Jacobs CR. Effects of high frequency loading on RANKL and OPG mRNA expression in ST-2 murine stromal cells Bmc Musculoskeletal Disorders. 10. PMID 19728893 DOI: 10.1186/1471-2474-10-109  0.64
2009 Arnsdorf EJ, Tummala P, Jacobs CR. Non-canonical Wnt signalling and N-cadherin related β-catenin signalling play a role in mechanically induced osteogenic cell fate Plos One. 4. PMID 19401766 DOI: 10.1371/journal.pone.0005388  0.64
2009 Wang L, Zhao R, Shi X, Wei T, Halloran BP, Clark DJ, Jacobs CR, Kingery WS. Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro. Bone. 45: 309-20. PMID 19379851 DOI: 10.1016/j.bone.2009.04.203  0.64
2009 Folgado J, Fernandes PR, Jacobs CR, Pellegrini JD. Influence of femoral stem geometry, material and extent of porous coating on bone ingrowth and atrophy in cementless total hip arthroplasty: an iterative finite element model Computer Methods in Biomechanics and Biomedical Engineering. 12: 135-145. PMID 19242833 DOI: 10.1080/10255840802546754  0.88
2009 Mishra A, Tummala P, King A, Lee B, Kraus M, Tse V, Jacobs CR. Buffered platelet-rich plasma enhances mesenchymal stem cell proliferation and chondrogenic differentiation. Tissue Engineering. Part C, Methods. 15: 431-5. PMID 19216642 DOI: 10.1089/ten.tec.2008.0534  0.64
2009 Arnsdorf EJ, Jones LM, Carter DR, Jacobs CR. The periosteum as a cellular source for functional tissue engineering. Tissue Engineering. Part A. 15: 2637-42. PMID 19207046 DOI: 10.1089/ten.TEA.2008.0244  0.64
2009 Arnsdorf EJ, Tummala P, Kwon RY, Jacobs CR. Mechanically induced osteogenic differentiation - The role of RhoA, ROCKII and cytoskeletal dynamics Journal of Cell Science. 122: 546-553. PMID 19174467 DOI: 10.1242/jcs.036293  0.64
2009 Temiyasathit S, Kwon RY, Tummala P, Quah CC, Jacobs CR. Adenylyl cyclase 6 mediates primary cilia-dependent changes in cyclic adenosine monophosphate in response to dynamic fluid flow Proceedings of the Asme Summer Bioengineering Conference 2009, Sbc2009. 1027-1028. DOI: 10.1115/SBC2009-206200  0.88
2009 Litzenberger JB, Tang WJ, Castillo AB, Jacobs CR. Deletion of β1 integrins from cortical osteocytes reduces load-induced bone formation Cellular and Molecular Bioengineering. 2: 416-424. DOI: 10.1007/s12195-009-0068-4  0.64
2009 Sittichokechaiwut A, Jacobs CR, Reilly GC. Mechanical responses of bone tissue formation in 3D engineered constructs via primary cilia European Cells and Materials. 18: 16.  0.88
2009 Kwon RY, Temiyasathit S, Tummala P, Quah C, Jacobs CR. Primary cilia mediate intracellular cAMP responses in bone cells exposed to dynamic fluid flow Proceedings of the Asme Summer Bioengineering Conference, Sbc2008. 321-322.  0.88
2008 Anderson CT, Castillo AB, Brugmann SA, Helms JA, Jacobs CR, Stearns T. Primary cilia: cellular sensors for the skeleton. Anatomical Record (Hoboken, N.J. : 2007). 291: 1074-8. PMID 18727074 DOI: 10.1002/ar.20754  0.64
2008 Kwon RY, Lew AJ, Jacobs CR. A microstructurally informed model for the mechanical response of three-dimensional actin networks. Computer Methods in Biomechanics and Biomedical Engineering. 11: 407-18. PMID 18568835 DOI: 10.1080/10255840801888686  0.88
2008 You L, Temiyasathit S, Lee P, Kim CH, Tummala P, Yao W, Kingery W, Malone AM, Kwon RY, Jacobs CR. Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading. Bone. 42: 172-9. PMID 17997378 DOI: 10.1016/j.bone.2007.09.047  0.64
2008 Sabsovich I, Clark JD, Liao G, Peltz G, Lindsey DP, Jacobs CR, Yao W, Guo TZ, Kingery WS. Bone microstructure and its associated genetic variability in 12 inbred mouse strains: microCT study and in silico genome scan. Bone. 42: 439-51. PMID 17967568 DOI: 10.1016/j.bone.2007.09.041  0.64
2008 Malone AMD, Anderson CT, Tummala P, Kwon RY, Johnston TR, Stearns T, Jacobs CR. Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, (13325-13330) DOI: 10.1073/pnas.0700636104) Proceedings of the National Academy of Sciences of the United States of America. 105: 825. DOI: 10.1073/pnas.0711497105  0.64
2007 Malone AM, Anderson CT, Stearns T, Jacobs CR. Primary cilia in bone. Journal of Musculoskeletal & Neuronal Interactions. 7: 301. PMID 18094482  0.88
2007 Jacobs CR. Primary cilia Journal of Musculoskeletal &Amp; Neuronal Interactions. 7: 297-298. PMID 18094479  0.88
2007 Malone AM, Anderson CT, Tummala P, Kwon RY, Johnston TR, Stearns T, Jacobs CR. Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 104: 13325-30. PMID 17673554 DOI: 10.1073/pnas.0700636104  0.64
2007 Kwon RY, Jacobs CR. Time-dependent deformations in bone cells exposed to fluid flow in vitro: investigating the role of cellular deformation in fluid flow-induced signaling Journal of Biomechanics. 40: 3162-3168. PMID 17559856 DOI: 10.1016/j.jbiomech.2007.04.003  0.64
2007 Malone AM, Batra NN, Shivaram G, Kwon RY, You L, Kim CH, Rodriguez J, Jair K, Jacobs CR. The role of actin cytoskeleton in oscillatory fluid flow-induced signaling in MC3T3-E1 osteoblasts. American Journal of Physiology. Cell Physiology. 292: C1830-6. PMID 17251324 DOI: 10.1152/ajpcell.00352.2005  0.64
2007 Godin LM, Suzuki S, Jacobs CR, Donahue HJ, Donahue SW. Mechanically induced intracellular calcium waves in osteoblasts demonstrate calcium fingerprints in bone cell mechanotransduction. Biomechanics and Modeling in Mechanobiology. 6: 391-8. PMID 17082961 DOI: 10.1007/s10237-006-0059-5  0.64
2006 Kim CH, You L, Yellowley CE, Jacobs CR. Oscillatory fluid flow-induced shear stress decreases osteoclastogenesis through RANKL and OPG signaling. Bone. 39: 1043-7. PMID 16860618 DOI: 10.1016/j.bone.2006.05.017  0.64
2006 Rubin J, Rubin C, Jacobs CR. Molecular pathways mediating mechanical signaling in bone. Gene. 367: 1-16. PMID 16361069 DOI: 10.1016/j.gene.2005.10.028  0.64
2006 Kwon RY, Jacobs CR. Viscoelasticity of bone cells exposed to fluid flow McB Molecular and Cellular Biomechanics. 3: 209.  0.64
2006 Litzenberger JB, Tummala P, Jacobs CR. Integrin signaling and the response of osteocytes to oscillatory fluid flow McB Molecular and Cellular Biomechanics. 3: 219-220.  0.64
2006 Malone AMD, Anderson CT, Tummala P, Stearns T, Jacobs CR. Primary cilia mediate PGE2 release in MC3T3-E1 osteoblasts McB Molecular and Cellular Biomechanics. 3: 207-208.  0.64
2006 Temiyasathit S, Tang WJ, Anderson CT, Stearns TP, Jacobs CR. Primary cilia as sensors of mechanical loading McB Molecular and Cellular Biomechanics. 3: 215-216.  0.64
2006 Clowes-Arnsdorf EJ, Kwon RY, Tummala P, Carter DR, Jacobs CR. The role of actin cytoskeletal tension in oscillatory fluid flow induced osteogenesis McB Molecular and Cellular Biomechanics. 3: 205-206.  0.64
2005 Batra NN, Li YJ, Yellowley CE, You L, Malone AM, Kim CH, Jacobs CR. Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells. Journal of Biomechanics. 38: 1909-17. PMID 16023480 DOI: 10.1016/j.jbiomech.2004.08.009  0.64
2005 Offley SC, Guo TZ, Wei T, Clark JD, Vogel H, Lindsey DP, Jacobs CR, Yao W, Lane NE, Kingery WS. Capsaicin-sensitive sensory neurons contribute to the maintenance of trabecular bone integrity Journal of Bone and Mineral Research. 20: 257-267. PMID 15647820 DOI: 10.1359/JBMR.041108  0.64
2005 Malone AM, Narain R, Jacobs CR. Biomechanical regulation of mesenchymal stem and progenitor cells and the implications for regenerative medicine Current Opinion in Orthopaedics. 16: 363-367. DOI: 10.1097/01.bco.0000178253.32694.f3  0.64
2005 Kwon RY, Jacobs CR, Lew AJ. Computational modeling of actin networks Proceedings of the 2005 Summer Bioengineering Conference. 2005: 1260-1261.  0.64
2005 Shivaram GM, Kim CH, Batra NN, Jacobs CR. Novel early response genes in MC3T3-E1 pre-osteoblasts exposed to oscillatory fluid flow Proceedings of the 2005 Summer Bioengineering Conference. 2005: 165-166.  0.64
2005 Malone AM, Cheng DK, Rodriguez JJ, Tummala P, Jacobs CR. The effects of oscillatory fluid flow on mapk phosphorylation in osteoblasts Proceedings of the 2005 Summer Bioengineering Conference. 2005: 1256-1257.  0.64
2004 Li YJ, Batra NN, You L, Meier SC, Coe IA, Yellowley CE, Jacobs CR. Oscillatory fluid flow affects human marrow stromal cell proliferation and differentiation. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 22: 1283-9. PMID 15475210 DOI: 10.1016/j.orthres.2004.04.002  0.64
2004 Haut Donahue TL, Genetos DC, Jacobs CR, Donahue HJ, Yellowley CE. Annexin V disruption impairs mechanically induced calcium signaling in osteoblastic cells Bone. 35: 656-663. PMID 15336601 DOI: 10.1016/j.bone.2004.04.025  0.88
2004 Edlich M, Yellowley CE, Jacobs CR, Donahue HJ. Cycle number and waveform of fluid flow affect bovine articular chondrocytes. Biorheology. 41: 315-22. PMID 15299264  0.64
2004 Haut Donahue TL, Hull ML, Rashid MM, Jacobs CR. The sensitivity of tibiofemoral contact pressure to the size and shape of the lateral and medial menisci. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 22: 807-14. PMID 15183438 DOI: 10.1016/j.orthres.2003.12.010  0.64
2004 Guo TZ, Offley SC, Boyd EA, Jacobs CR, Kingery WS. Substance P signaling contributes to the vascular and nociceptive abnormalities observed in a tibial fracture rat model of complex regional pain syndrome type I Pain. 108: 95-107. PMID 15109512 DOI: 10.1016/j.pain.2003.12.010  0.64
2003 Kingery WS, Offley SC, Guo TZ, Davies MF, Clark JD, Jacobs CR. A substance P receptor (NK1) antagonist enhances the widespread osteoporotic effects of sciatic nerve section Bone. 33: 927-936. PMID 14678852 DOI: 10.1016/j.bone.2003.07.003  0.64
2003 Alford AI, Yellowley CE, Jacobs CR, Donahue HJ. Increases in Cytosolic Calcium, but not Fluid Flow, Affect Aggrecan mRNA Levels in Articular Chondrocytes Journal of Cellular Biochemistry. 90: 938-944. PMID 14624453 DOI: 10.1002/jcb.10715  0.64
2003 Reilly GC, Haut TR, Yellowley CE, Donahue HJ, Jacobs CR. Fluid flow induced PGE2 release by bone cells is reduced by glycocalyx degradation whereas calcium signals are not. Biorheology. 40: 591-603. PMID 14610310  0.64
2003 Alford AI, Jacobs CR, Donahue HJ. Oscillating fluid flow regulates gap junction communication in osteocytic MLO-Y4 cells by an ERK1/2 MAP kinase-dependent mechanism Bone. 33: 64-70. PMID 12919700 DOI: 10.1016/S8756-3282(03)00167-4  0.64
2003 Donahue TLH, Haut TR, Yellowley CE, Donahue HJ, Jacobs CR. Mechanosensitivity of bone cells to oscillating fluid flow induced shear stress may be modulated by chemotransport Journal of Biomechanics. 36: 1363-1371. PMID 12893045 DOI: 10.1016/S0021-9290(03)00118-0  0.64
2003 Saunders MM, You J, Zhou Z, Li Z, Yellowley CE, Kunze EL, Jacobs CR, Donahue HJ. Fluid flow-induced prostaglandin E2 response of osteoblastic ROS 17/2.8 cells is gap junction-mediated and independent of cytosolic calcium Bone. 32: 350-356. PMID 12689677 DOI: 10.1016/S8756-3282(03)00025-5  0.64
2003 Saunders MM, Schwentker EP, Kay DB, Bennett G, Jacobs CR, Verstraete MC, Njus GO. Finite element analysis as a tool for parametric prosthetic foot design and evaluation. Technique development in the solid ankle cushioned heel (SACH) foot. Computer Methods in Biomechanics and Biomedical Engineering. 6: 75-87. PMID 12623440 DOI: 10.1080/1025584021000048974  0.64
2003 Donahue TL, Rosenberg G, Jacobs CR, Weiss WJ. Finite element analysis of stresses developed in blood sacs of a pusherplate blood pump. Computer Methods in Biomechanics and Biomedical Engineering. 6: 7-15. PMID 12623433 DOI: 10.1080/1025584031000078943  0.64
2003 Donahue SW, Donahue HJ, Jacobs CR. Osteoblastic cells have refractory periods for fluid-flow-induced intracellular calcium oscillations for short bouts of flow and display multiple low-magnitude oscillations during long-term flow. Journal of Biomechanics. 36: 35-43. PMID 12485636 DOI: 10.1016/S0021-9290(02)00318-4  0.64
2003 Haut Donahue TL, Hull ML, Rashid MM, Jacobs CR. How the stiffness of meniscal attachments and meniscal material properties affect tibio-femoral contact pressure computed using a validated finite element model of the human knee joint. Journal of Biomechanics. 36: 19-34. PMID 12485635 DOI: 10.1016/S0021-9290(02)00305-6  0.64
2002 You J, Jacobs CR, Steinberg TH, Donahue HJ. P2Y purinoceptors are responsible for oscillatory fluid flow-induced intracellular calcium mobilization in osteoblastic cells. The Journal of Biological Chemistry. 277: 48724-9. PMID 12376532 DOI: 10.1074/jbc.M209245200  0.64
2002 Donahue TL, Hull ML, Rashid MM, Jacobs CR. A finite element model of the human knee joint for the study of tibio-femoral contact. Journal of Biomechanical Engineering. 124: 273-80. PMID 12071261 DOI: 10.1115/1.1470171  0.64
2002 Buhl KM, Jacobs CR, Turner RT, Evans GL, Farrell PA, Donahue HJ. Parallel changes in extracellular matrix protein gene expression, bone formation and biomechanical properties in aging rat bone Journal of Musculoskeletal Research. 6: 157-169.  0.64
2001 Saunders MM, You J, Trosko JE, Yamasaki H, Li Z, Donahue HJ, Jacobs CR. Gap junctions and fluid flow response in MC3T3-E1 cells American Journal of Physiology - Cell Physiology. 281. PMID 11698250  0.88
2001 Donahue SW, Jacobs CR, Donahue HJ. Flow-induced calcium oscillations in rat osteoblasts are age, loading frequency, and shear stress dependent American Journal of Physiology - Cell Physiology. 281: C1635-C1641. PMID 11600427  0.64
2001 Edlich M, Yellowley CE, Jacobs CR, Donahue HJ. Oscillating fluid flow regulates cytosolic calcium concentration in bovine articular chondrocytes Journal of Biomechanics. 34: 59-65. PMID 11425081 DOI: 10.1016/S0021-9290(00)00158-5  0.64
2001 You J, Reilly GC, Zhen X, Yellowley CE, Chen Q, Donahue HJ, Jacobs CR. Osteopontin Gene Regulation by Oscillatory Fluid Flow via Intracellular Calcium Mobilization and Activation of Mitogen-activated Protein Kinase in MC3T3-E1 Osteoblasts Journal of Biological Chemistry. 276: 13365-13371. PMID 11278573 DOI: 10.1074/jbc.M009846200  0.64
2001 Buhl KM, Jacobs CR, Turner RT, Evans GL, Farrell PA, Donahue HJ. Aged bone displays an increased responsiveness to low-intensity resistance exercise Journal of Applied Physiology. 90: 1359-1364. PMID 11247935  0.64
2001 Kurokouchi K, Jacobs CR, Donahue HJ. Oscillating Fluid Flow Inhibits TNF-α-induced NF-κB Activation via an IκB Kinase Pathway in Osteoblast-like UMR106 Cells Journal of Biological Chemistry. 276: 13499-13504. PMID 11096064 DOI: 10.1074/jbc.M003795200  0.64
2001 Jacobs CR, Poncet S. Large scale finite element modeling of trabecular bone tissue: An error estimate using PMMA replicas with realistic microarchitecture American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 231-232.  0.64
2001 Blankenhorn BD, Pellegrini VD, Jacobs CR. The influence of coronal malalignment on the contact area of total knee prostheses American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 747-748.  0.64
2001 You J, Saunders MM, Yellowley CE, Donahue HJ, Jacobs CR. Oscillatory flow-induced prostaglandin E2 release involves protein kinase a and cyclooxygenase-2 in MC3T3-E1 osteoblasts American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 163-164.  0.64
2001 Haut Donahue TL, Hull ML, Rashid MM, Jacobs CR. The sensitivity of tibio-femoral contact to parameters describing the geometry of the lateral and medial menisci American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 227-228.  0.64
2001 Jacobs CR, You J, Reilly G, Saunders MM, Kurokouchi K, Yellowley CE, Donahue HJ. An overview of oscialltory fluid flow as a potent loading-induced physical signal in bone cells American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 339-340.  0.64
2000 Jacobs CR, Yellowley CE, Nelson DV, Donahue HJ. Analysis of Time-Varying Biological Data Using Rainflow Cycle Counting. Computer Methods in Biomechanics and Biomedical Engineering. 3: 31-40. PMID 11264837 DOI: 10.1080/10255840008915252  0.64
2000 Black KP, Saunders MM, Stube KC, Moulton MJR, Jacobs CR. Effects of interference fit screw length on tibial tunnel fixation for anterior cruciate ligament reconstruction American Journal of Sports Medicine. 28: 846-849. PMID 11101107  0.64
2000 You J, Yellowley CE, Donahue HJ, Zhang Y, Chen Q, Jacobs CR. Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow Journal of Biomechanical Engineering. 122: 387-393. PMID 11036562 DOI: 10.1115/1.1287161  0.64
2000 Lesh ML, Schneider DJ, Deol G, Davis B, Jacobs CR, Pellegrini V.D. J. The consequences of anterior femoral notching in total knee arthroplasty: A Biomechanical study Journal of Bone and Joint Surgery - Series A. 82: 1096-1101. PMID 10954098  0.64
2000 Eckstein F, Merz B, Jacobs CR. Effects of joint incongruity on articular pressure distribution and subchondral bone remodeling Advances in Anatomy, Embryology, and Cell Biology. 152. PMID 10857219  0.64
2000 Jacobs CR. The mechanobiology of cancellous bone structural adaptation Journal of Rehabilitation Research and Development. 37: 209-216. PMID 10850827  0.64
2000 Malecki EA, Buhl KM, Beard JL, Jacobs CR, Connor JR, Donahue HJ. Bone structural and mechanical properties are affected by hypotransferrinemia but not by iron deficiency in mice Journal of Bone and Mineral Research. 15: 271-277. PMID 10703928  0.64
2000 Yellowley CE, Li Z, Zhou Z, Jacobs CR, Donahue HJ. Functional gap junctions between osteocytic and osteoblastic cells Journal of Bone and Mineral Research. 15: 209-217. PMID 10703922  0.64
2000 Donahue TH, Rashid MM, Hull ML, Jacobs CR. Finite element model of the human knee joint to study tibio-femoral contact mechanics American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 48: 155-156.  0.64
1999 Fischer KJ, Jacobs CR, Levenston ME, Cody DD, Carter DR. Proximal Femoral Density Patterns are Consistent with Bicentric Joint Loads. Computer Methods in Biomechanics and Biomedical Engineering. 2: 271-283. PMID 11264832 DOI: 10.1080/10255849908907992  0.88
1999 Jacobs CR, Davis BR, Rieger CJ, Francis JJ, Saad M, Fyhrie DP. NACOB presentation to ASB Young Scientist Award: Postdoctoral. The impact of boundary conditions and mesh size on the accuracy of cancellous bone tissue modulus determination using large-scale finite-element modeling. North American Congress on Biomechanics. Journal of Biomechanics. 32: 1159-64. PMID 10541065 DOI: 10.1016/S0021-9290(99)00115-3  0.88
1999 Yellowley CE, Jacobs CR, Donahue HJ. Mechanisms contributing to fluid-flow-induced Ca2+ mobilization in articular chondrocytes Journal of Cellular Physiology. 180: 402-408. PMID 10430180 DOI: 10.1002/(SICI)1097-4652(199909)180:3<402::AID-JCP11>3.0.CO;2-4  0.64
1999 Segal LS, Schneider DJ, Berlin JM, Bruno A, Davis BR, Jacobs CR. The contribution of the ossific nucleus to the structural stiffness of the capital femoral epiphysis: A porcine model for DDH Journal of Pediatric Orthopaedics. 19: 433-437. PMID 10412989 DOI: 10.1097/00004694-199907000-00003  0.64
1999 Black KP, Schneider DJ, Yu JR, Jacobs CR. Biomechanics of the Bankart repair: The relationship between glenohumeral translation and labral fixation site American Journal of Sports Medicine. 27: 339-344. PMID 10352770  0.88
1999 Barr JD, Hoffman EJ, Davis BR, Edgar KA, Jacobs CR. Microcatheter adhesion of cyanoacrylates: comparison of normal butyl cyanoacrylate to 2-hexyl cyanoacrylate. Journal of Vascular and Interventional Radiology : Jvir. 10: 165-8. PMID 10082103  0.64
1999 Eckstein F, Merz B, Schön M, Jacobs CR, Putz R. Tension and bending, but not compression alone determine the functional adaptation of subchondral bone in incongruous joints Anatomy and Embryology. 199: 85-97. PMID 9924938 DOI: 10.1007/s004290050212  0.64
1999 Jacobs CR. Large-scale finite element solutions on workstation class computers American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 42: 405-406.  0.64
1999 You J, Yellowley CE, Donahue HJ, Jacobs CR. Physiological levels of substrate deformation are less stimulatory to bone cells compared to fluid flow American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 43: 161-162.  0.64
1999 Edlich MJ, Jacobs CR, Yellowley CE, Donahue HJ. Differential effect of steady and oscillating flow on intracellular calcium dynamics and the influence of FBS on bovine articular chondrocytes American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 42: 255-256.  0.64
1998 Fischer KJ, Jacobs CR, Levenston ME, Cody DD, Carter DR. Bone Load Estimation for the Proximal Femur Using Single Energy Quantitative CT Data. Computer Methods in Biomechanics and Biomedical Engineering. 1: 233-245. PMID 11264806 DOI: 10.1080/01495739808936704  0.88
1998 Jacobs CR, Yellowley CE, Davis BR, Zhou Z, Cimbala JM, Donahue HJ. Differential effect of steady versus oscillating flow on bone cells Journal of Biomechanics. 31: 969-976. PMID 9880053 DOI: 10.1016/S0021-9290(98)00114-6  0.88
1998 Fedok FG, Van Kooten DW, DeJoseph LM, McGinn JD, Sobota B, Levin RJ, Jacobs CR. Plating techniques and plate orientation in repair of mandibular angle fractures: An in vitro study Laryngoscope. 108: 1218-1224. PMID 9707247 DOI: 10.1097/00005537-199808000-00022  0.64
1998 Buhl KM, Jacobs CR, Donahue HJ. Comprehensive investigation of skeletal dynamics in the aging rat Bioengineering, Proceedings of the Northeast Conference. 58-60.  0.64
1998 Jacobs CR, Davis BR, Naidu SH, Pellegrini VD, Case KL. Comparison of the fatigue lifetimes of simplex P and osteobond bone cement American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 39: 353-354.  0.64
1997 Jacobs CR, Eckstein F. Computer simulation of subchondral bone adaptation to mechanical loading in an incongruous joint Anatomical Record. 249: 317-326. PMID 9372165 DOI: 10.1002/(SICI)1097-0185(199711)249:3<317::AID-AR2>3.0.CO;2-R  0.64
1997 Yellowley CE, Jacobs CR, Li Z, Zhou Z, Donahue HJ. Effects of fluid flow on intracellular calcium in bovine articular chondrocytes American Journal of Physiology - Cell Physiology. 273. PMID 9252439  0.64
1997 Jacobs CR, Simo JC, Beaupré GS, Carter DR. Adaptive bone remodeling incorporating simultaneous density and anisotropy considerations. Journal of Biomechanics. 30: 603-13. PMID 9165394 DOI: 10.1016/S0021-9290(96)00189-3  0.64
1997 Fischer KJ, Jacobs CR, Levenston ME, Carter DR. Observations of convergence and uniqueness of node-based bone remodeling simulations Annals of Biomedical Engineering. 25: 261-268. PMID 9084831  0.88
1996 Fischer KJ, Jacobs CR, Levenston ME, Carter DR. Different loads can produce similar bone density distributions Bone. 19: 127-135. PMID 8853856 DOI: 10.1016/8756-3282(96)00140-8  0.88
1995 Jacobs CR, Levenston ME, Beaupré GS, Simo JC, Carter DR. Numerical instabilities in bone remodeling simulations: the advantages of a node-based finite element approach. Journal of Biomechanics. 28: 449-59. PMID 7738054 DOI: 10.1016/0021-9290(94)00087-K  0.64
1995 Fischer KJ, Jacobs CR, Carter DR. Computational method for determination of bone and joint loads using bone density distributions Journal of Biomechanics. 28: 1127-1135. PMID 7559684 DOI: 10.1016/0021-9290(94)00182-4  0.64
1994 Levenston ME, Beaupré GS, Jacobs CR, Carter DR. The role of loading memory in bone adaptation simulations Bone. 15: 177-186. PMID 8086235 DOI: 10.1016/8756-3282(94)90705-6  0.88
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