Peter W. Zandstra - Publications

Affiliations: 
Biomedical Engineering University of Toronto, Toronto, ON, Canada 
Area:
Biomedical Engineering, Molecular Biology, Cell Biology
Website:
https://www.ccrm.ca/Peter_Zandstra

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhang S, Scott EY, Singh J, Chen Y, Zhang Y, Elsayed M, Chamberlain MD, Shakiba N, Adams K, Yu S, Morshead CM, Zandstra PW, Wheeler AR. The optoelectronic microrobot: A versatile toolbox for micromanipulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31289234 DOI: 10.1073/pnas.1903406116  0.36
2019 Shakiba N, Fahmy A, Jayakumaran G, McGibbon S, David L, Trcka D, Elbaz J, Puri MC, Nagy A, van der Kooy D, Goyal S, Wrana JL, Zandstra PW. Cell competition during reprogramming gives rise to dominant clones. Science (New York, N.Y.). PMID 30898844 DOI: 10.1126/science.aan0925  0.56
2018 Yachie-Kinoshita A, Onishi K, Ostblom J, Langley MA, Posfai E, Rossant J, Zandstra PW. Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions. Molecular Systems Biology. 14: e7952. PMID 29378814  0.88
2017 Wang W, Fujii H, Kim HJ, Hermans K, Usenko T, Xie S, Luo ZJ, Ma J, Celso CL, Dick JE, Schroeder T, Krueger J, Wall D, Egeler RM, Zandstra PW. Enhanced human hematopoietic stem and progenitor cell engraftment by blocking donor T cell-mediated TNFα signaling. Science Translational Medicine. 9. PMID 29263228 DOI: 10.1126/scitranslmed.aag3214  0.4
2017 Zhou W, Mahshid SS, Wang W, Vallée-Bélisle A, Zandstra PW, Sargent EH, Kelley SO. Steric Hindrance Assay for Secreted Factors in Stem Cell Culture. Acs Sensors. 2: 495-500. PMID 28723184 DOI: 10.1021/acssensors.7b00136  0.4
2016 Knapp DJ, Hammond CA, Aghaeepour N, Miller PH, Pellacani D, Beer PA, Sachs K, Qiao W, Wang W, Humphries RK, Sauvageau G, Zandstra PW, Bendall SC, Nolan GP, Hansen C, et al. Distinct signaling programs control human hematopoietic stem cell survival and proliferation. Blood. PMID 27827829 DOI: 10.1182/blood-2016-09-740654  0.96
2016 Müller E, Wang W, Qiao W, Bornhäuser M, Zandstra PW, Werner C, Pompe T. Distinguishing autocrine and paracrine signals in hematopoietic stem cell culture using a biofunctional microcavity platform. Scientific Reports. 6: 31951. PMID 27535453 DOI: 10.1038/srep31951  1
2016 Nazareth EJ, Rahman N, Yin T, Zandstra PW. A Multi-Lineage Screen Reveals mTORC1 Inhibition Enhances Human Pluripotent Stem Cell Mesendoderm and Blood Progenitor Production. Stem Cell Reports. 6: 679-91. PMID 27132889 DOI: 10.1016/j.stemcr.2016.04.003  1
2016 Lechman ER, Gentner B, Ng SW, Schoof EM, van Galen P, Kennedy JA, Nucera S, Ciceri F, Kaufmann KB, Takayama N, Dobson SM, Trotman-Grant A, Krivdova G, Elzinga J, Mitchell A, ... ... Zandstra PW, et al. miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells. Cancer Cell. 29: 602-606. PMID 27070706 DOI: 10.1016/j.ccell.2016.03.015  1
2016 Lipsitz YY, Timmins NE, Zandstra PW. Quality cell therapy manufacturing by design. Nature Biotechnology. 34: 393-400. PMID 27054995 DOI: 10.1038/nbt.3525  1
2016 Wang Y, Li Y, Thérien-Aubin H, Ma J, Zandstra PW, Kumacheva E. Two-dimensional arrays of cell-laden polymer hydrogel modules. Biomicrofluidics. 10: 014110. PMID 26858822 DOI: 10.1063/1.4940430  1
2016 Lechman ER, Gentner B, Ng SW, Schoof EM, van Galen P, Kennedy JA, Nucera S, Ciceri F, Kaufmann KB, Takayama N, Dobson SM, Trotman-Grant A, Krivdova G, Elzinga J, Mitchell A, ... ... Zandstra PW, et al. miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells. Cancer Cell. PMID 26832662 DOI: 10.1016/j.ccell.2015.12.011  1
2015 Caldwell J, Wang W, Zandstra PW. Proportional-Integral-Derivative (PID) Control of Secreted Factors for Blood Stem Cell Culture. Plos One. 10: e0137392. PMID 26348930 DOI: 10.1371/journal.pone.0137392  1
2015 Onishi K, Zandstra PW. LIF signaling in stem cells and development. Development (Cambridge, England). 142: 2230-6. PMID 26130754 DOI: 10.1242/dev.117598  1
2015 Kana K, Song H, Laschinger C, Zandstra PW, Radisic M. PI3 Kinase Phosphorylation is linked to improved electrical excitability in an in vitro Engineered Heart Tissue Disease Model System. Tissue Engineering. Part A. PMID 26120935 DOI: 10.1089/ten.TEA.2014.0412  1
2015 Hussein SM, Puri MC, Tonge PD, Benevento M, Corso AJ, Clancy JL, Mosbergen R, Li M, Lee DS, Cloonan N, Wood DL, Munoz J, Middleton R, Korn O, Patel HR, ... ... Zandstra PW, et al. Corrigendum: Genome-wide characterization of the routes to pluripotency. Nature. PMID 26083747 DOI: 10.1038/nature14606  0.56
2015 Shakiba N, White CA, Lipsitz YY, Yachie-Kinoshita A, Tonge PD, Hussein SM, Puri MC, Elbaz J, Morrissey-Scoot J, Li M, Munoz J, Benevento M, Rogers IM, Hanna JH, Heck AJ, ... ... Zandstra PW, et al. CD24 tracks divergent pluripotent states in mouse and human cells. Nature Communications. 6: 7329. PMID 26076835 DOI: 10.1038/ncomms8329  1
2015 Qiao W, Zandstra PW. Bringing Blood Stem Cell Phenotype, Genotype, and Function Closer Together. Cell Stem Cell. 16: 574-5. PMID 26046754 DOI: 10.1016/j.stem.2015.05.001  1
2015 Futrega K, Palmer JS, Kinney M, Lott WB, Ungrin MD, Zandstra PW, Doran MR. The microwell-mesh: A novel device and protocol for the high throughput manufacturing of cartilage microtissues. Biomaterials. 62: 1-12. PMID 26010218 DOI: 10.1016/j.biomaterials.2015.05.013  1
2015 Goyal S, Zandstra PW. Stem cells: Chasing blood. Nature. 518: 488-90. PMID 25686602 DOI: 10.1038/nature14203  1
2015 Thavandiran N, Dubois N, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande VS, McGarry JP, Chen CS, Nanthakumar K, Keller GM, Radisic M, Zandstra PW. Correction: Design and formulation of functional pluripotent stem cell-derived cardiac microtissues (Proceedings of the National Academy of Sciences (2013) 110, (E4698-E4707) DOI:10.1073/pnas.1311120110) Proceedings of the National Academy of Sciences of the United States of America. 112: E3151. DOI: 10.1073/pnas.1509023112  1
2014 Hussein SM, Puri MC, Tonge PD, Benevento M, Corso AJ, Clancy JL, Mosbergen R, Li M, Lee DS, Cloonan N, Wood DL, Munoz J, Middleton R, Korn O, Patel HR, ... ... Zandstra PW, et al. Genome-wide characterization of the routes to pluripotency. Nature. 516: 198-206. PMID 25503233 DOI: 10.1038/nature14046  1
2014 Prowse AB, Timmins NE, Yau TM, Li RK, Weisel RD, Keller G, Zandstra PW. Transforming the promise of pluripotent stem cell-derived cardiomyocytes to a therapy: challenges and solutions for clinical trials. The Canadian Journal of Cardiology. 30: 1335-49. PMID 25442434 DOI: 10.1016/j.cjca.2014.08.005  1
2014 Fares I, Chagraoui J, Gareau Y, Gingras S, Ruel R, Mayotte N, Csaszar E, Knapp DJ, Miller P, Ngom M, Imren S, Roy DC, Watts KL, Kiem HP, Herrington R, ... ... Zandstra PW, et al. Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal. Science (New York, N.Y.). 345: 1509-12. PMID 25237102 DOI: 10.1126/science.1256337  1
2014 Onishi K, Tonge PD, Nagy A, Zandstra PW. Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency. Stem Cell Reports. 3: 156-68. PMID 25068129 DOI: 10.1016/j.stemcr.2014.04.019  1
2014 Qiao W, Wang W, Laurenti E, Turinsky AL, Wodak SJ, Bader GD, Dick JE, Zandstra PW. Intercellular network structure and regulatory motifs in the human hematopoietic system. Molecular Systems Biology. 10: 741. PMID 25028490 DOI: 10.15252/msb.20145141  1
2014 Lücker PB, Javaherian S, Soleas JP, Halverson D, Zandstra PW, McGuigan AP. A microgroove patterned multiwell cell culture plate for high-throughput studies of cell alignment. Biotechnology and Bioengineering. 111: 2537-48. PMID 24889796 DOI: 10.1002/bit.25298  1
2014 Loring JF, McDevitt TC, Palecek SP, Schaffer DV, Zandstra PW, Nerem RM. A global assessment of stem cell engineering. Tissue Engineering. Part A. 20: 2575-89. PMID 24428577 DOI: 10.1089/ten.TEA.2013.0468  1
2014 Csaszar E, Chen K, Caldwell J, Chan W, Zandstra PW. Real-time monitoring and control of soluble signaling factors enables enhanced progenitor cell outputs from human cord blood stem cell cultures. Biotechnology and Bioengineering. 111: 1258-64. PMID 24284903 DOI: 10.1002/bit.25163  1
2014 Csaszar E, Wang W, Usenko T, Qiao W, Delaney C, Bernstein ID, Zandstra PW. Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling. Blood. 123: 650-8. PMID 24243972 DOI: 10.1182/blood-2013-08-520445  1
2014 DeVeale B, Bausch-Fluck D, Seaberg R, Runciman S, Akbarian V, Karpowicz P, Yoon C, Song H, Leeder R, Zandstra PW, Wollscheid B, van der Kooy D. Surfaceome profiling reveals regulators of neural stem cell function. Stem Cells (Dayton, Ohio). 32: 258-68. PMID 24023036 DOI: 10.1002/stem.1550  1
2013 Thavandiran N, Dubois N, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande VS, McGarry JP, Chen CS, Nanthakumar K, Keller GM, Radisic M, Zandstra PW. Design and formulation of functional pluripotent stem cell-derived cardiac microtissues. Proceedings of the National Academy of Sciences of the United States of America. 110: E4698-707. PMID 24255110 DOI: 10.1073/pnas.1311120110  1
2013 DeVeale B, Brokhman I, Mohseni P, Babak T, Yoon C, Lin A, Onishi K, Tomilin A, Pevny L, Zandstra PW, Nagy A, van der Kooy D. Oct4 is required ~E7.5 for proliferation in the primitive streak. Plos Genetics. 9: e1003957. PMID 24244203 DOI: 10.1371/journal.pgen.1003957  1
2013 Nazareth EJ, Ostblom JE, Lücker PB, Shukla S, Alvarez MM, Oh SK, Yin T, Zandstra PW. High-throughput fingerprinting of human pluripotent stem cell fate responses and lineage bias. Nature Methods. 10: 1225-31. PMID 24141495 DOI: 10.1038/nmeth.2684  1
2013 Stevens KR, Ungrin MD, Schwartz RE, Ng S, Carvalho B, Christine KS, Chaturvedi RR, Li CY, Zandstra PW, Chen CS, Bhatia SN. InVERT molding for scalable control of tissue microarchitecture. Nature Communications. 4: 1847. PMID 23673632 DOI: 10.1038/ncomms2853  1
2013 Guo H, Isserlin R, Chen X, Wang W, Phanse S, Zandstra PW, Paddison PJ, Emili A. Integrative network analysis of signaling in human CD34(+) hematopoietic progenitor cells by global phosphoproteomic profiling using TiO2 enrichment combined with 2D LC-MS/MS and pathway mapping. Proteomics. 13: 1325-33. PMID 23401153 DOI: 10.1002/pmic.201200369  1
2013 Csaszar E, Cohen S, Zandstra PW. Blood stem cell products: toward sustainable benchmarks for clinical translation. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 201-10. PMID 23299858 DOI: 10.1002/bies.201200118  1
2013 Baptista RP, Fluri DA, Zandstra PW. High density continuous production of murine pluripotent cells in an acoustic perfused bioreactor at different oxygen concentrations. Biotechnology and Bioengineering. 110: 648-55. PMID 22949074 DOI: 10.1002/bit.24717  1
2013 Hogle LF, Palecek SP, Schaffer D, Zandstra PW. Characterizing international stem cell research niches Regenerative Medicine Ethics: Governing Research and Knowledge Practices. 29-65. DOI: 10.1007/978-1-4614-9062-3_2  1
2012 Qiao W, Quon G, Csaszar E, Yu M, Morris Q, Zandstra PW. PERT: a method for expression deconvolution of human blood samples from varied microenvironmental and developmental conditions. Plos Computational Biology. 8: e1002838. PMID 23284283 DOI: 10.1371/journal.pcbi.1002838  1
2012 Onishi K, Tonge PD, Nagy A, Zandstra PW. Microenvironment-mediated reversion of epiblast stem cells by reactivation of repressed JAK-STAT signaling. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 1367-76. PMID 22990140 DOI: 10.1039/c2ib20098h  1
2012 Reynolds JG, Geretti E, Hendriks BS, Lee H, Leonard SC, Klinz SG, Noble CO, Lücker PB, Zandstra PW, Drummond DC, Olivier KJ, Nielsen UB, Niyikiza C, Agresta SV, Wickham TJ. HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity. Toxicology and Applied Pharmacology. 262: 1-10. PMID 22676972 DOI: 10.1016/j.taap.2012.04.008  1
2012 Fluri DA, Tonge PD, Song H, Baptista RP, Shakiba N, Shukla S, Clarke G, Nagy A, Zandstra PW. Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures. Nature Methods. 9: 509-16. PMID 22447133 DOI: 10.1038/nmeth.1939  1
2012 Woodford C, Zandstra PW. Tissue engineering 2.0: guiding self-organization during pluripotent stem cell differentiation. Current Opinion in Biotechnology. 23: 810-9. PMID 22444525 DOI: 10.1016/j.copbio.2012.03.003  1
2012 Moledina F, Clarke G, Oskooei A, Onishi K, Günther A, Zandstra PW. Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 3264-9. PMID 22334649 DOI: 10.1073/pnas.1111478109  1
2012 Csaszar E, Kirouac DC, Yu M, Wang W, Qiao W, Cooke MP, Boitano AE, Ito C, Zandstra PW. Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling. Cell Stem Cell. 10: 218-29. PMID 22305571 DOI: 10.1016/j.stem.2012.01.003  1
2012 Ungrin MD, Clarke G, Yin T, Niebrugge S, Nostro MC, Sarangi F, Wood G, Keller G, Zandstra PW. Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics. Biotechnology and Bioengineering. 109: 853-66. PMID 22139975 DOI: 10.1002/bit.24375  1
2012 Boudou T, Legant WR, Mu A, Borochin MA, Thavandiran N, Radisic M, Zandstra PW, Epstein JA, Margulies KB, Chen CS. A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues. Tissue Engineering. Part A. 18: 910-9. PMID 22092279 DOI: 10.1089/ten.TEA.2011.0341  1
2012 Purpura KA, Bratt-Leal AM, Hammersmith KA, McDevitt TC, Zandstra PW. Systematic engineering of 3D pluripotent stem cell niches to guide blood development. Biomaterials. 33: 1271-80. PMID 22079776 DOI: 10.1016/j.biomaterials.2011.10.051  1
2012 Parrag IC, Zandstra PW, Woodhouse KA. Fiber alignment and coculture with fibroblasts improves the differentiated phenotype of murine embryonic stem cell-derived cardiomyocytes for cardiac tissue engineering. Biotechnology and Bioengineering. 109: 813-22. PMID 22006660 DOI: 10.1002/bit.23353  1
2011 Gabut M, Samavarchi-Tehrani P, Wang X, Slobodeniuc V, O'Hanlon D, Sung HK, Alvarez M, Talukder S, Pan Q, Mazzoni EO, Nedelec S, Wichterle H, Woltjen K, Hughes TR, Zandstra PW, et al. An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell. 147: 132-46. PMID 21924763 DOI: 10.1016/j.cell.2011.08.023  1
2011 Matsuura K, Masuda S, Haraguchi Y, Yasuda N, Shimizu T, Hagiwara N, Zandstra PW, Okano T. Creation of mouse embryonic stem cell-derived cardiac cell sheets. Biomaterials. 32: 7355-62. PMID 21807408 DOI: 10.1016/j.biomaterials.2011.05.042  1
2011 Tumarkin E, Tzadu L, Csaszar E, Seo M, Zhang H, Lee A, Peerani R, Purpura K, Zandstra PW, Kumacheva E. High-throughput combinatorial cell co-culture using microfluidics. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 653-62. PMID 21526262 DOI: 10.1039/c1ib00002k  1
2011 Song H, Zandstra PW, Radisic M. Engineered heart tissue model of diabetic myocardium. Tissue Engineering. Part A. 17: 1869-78. PMID 21417718 DOI: 10.1089/ten.TEA.2010.0617  1
2011 Bauwens CL, Song H, Thavandiran N, Ungrin M, Massé S, Nanthakumar K, Seguin C, Zandstra PW. Geometric control of cardiomyogenic induction in human pluripotent stem cells. Tissue Engineering. Part A. 17: 1901-9. PMID 21417693 DOI: 10.1089/ten.TEA.2010.0563  1
2011 Dengler J, Song H, Thavandiran N, Massé S, Wood GA, Nanthakumar K, Zandstra PW, Radisic M. Engineered heart tissue enables study of residual undifferentiated embryonic stem cell activity in a cardiac environment. Biotechnology and Bioengineering. 108: 704-19. PMID 21246514 DOI: 10.1002/bit.22987  1
2011 Kumachev A, Greener J, Tumarkin E, Eiser E, Zandstra PW, Kumacheva E. High-throughput generation of hydrogel microbeads with varying elasticity for cell encapsulation. Biomaterials. 32: 1477-83. PMID 21095000 DOI: 10.1016/j.biomaterials.2010.10.033  1
2011 Bratt-Leal AM, Carpenedo RL, Ungrin MD, Zandstra PW, McDevitt TC. Incorporation of biomaterials in multicellular aggregates modulates pluripotent stem cell differentiation. Biomaterials. 32: 48-56. PMID 20864164 DOI: 10.1016/j.biomaterials.2010.08.113  1
2010 Kirouac DC, Ito C, Csaszar E, Roch A, Yu M, Sykes EA, Bader GD, Zandstra PW. Dynamic interaction networks in a hierarchically organized tissue. Molecular Systems Biology. 6: 417. PMID 20924352 DOI: 10.1038/msb.2010.71  1
2010 Rahman N, Purpura KA, Wylie RG, Zandstra PW, Shoichet MS. The use of vascular endothelial growth factor functionalized agarose to guide pluripotent stem cell aggregates toward blood progenitor cells Biomaterials. 31: 8262-8270. PMID 20684984 DOI: 10.1016/j.biomaterials.2010.07.040  1
2010 Hewel JA, Liu J, Onishi K, Fong V, Chandran S, Olsen JB, Pogoutse O, Schutkowski M, Wenschuh H, Winkler DF, Eckler L, Zandstra PW, Emili A. Synthetic peptide arrays for pathway-level protein monitoring by liquid chromatography-tandem mass spectrometry. Molecular & Cellular Proteomics : McP. 9: 2460-73. PMID 20467045 DOI: 10.1074/mcp.M900456-MCP200  1
2010 Peerani R, Zandstra PW. Enabling stem cell therapies through synthetic stem cell-niche engineering. The Journal of Clinical Investigation. 120: 60-70. PMID 20051637 DOI: 10.1172/JCI41158  1
2010 Ito CY, Kirouac DC, Madlambayan GJ, Yu M, Rogers I, Zandstra PW. The AC133+CD38-, but not the rhodamine-low, phenotype tracks LTC-IC and SRC function in human cord blood ex vivo expansion cultures. Blood. 115: 257-60. PMID 19897585 DOI: 10.1182/blood-2009-07-228106  1
2010 Song H, Yoon C, Kattman SJ, Dengler J, Massé S, Thavaratnam T, Gewarges M, Nanthakumar K, Rubart M, Keller GM, Radisic M, Zandstra PW. Interrogating functional integration between injected pluripotent stem cell-derived cells and surrogate cardiac tissue. Proceedings of the National Academy of Sciences of the United States of America. 107: 3329-34. PMID 19846783 DOI: 10.1073/pnas.0905729106  1
2009 Peerani R, Onishi K, Mahdavi A, Kumacheva E, Zandstra PW. Manipulation of signaling thresholds in "engineered stem cell niches" identifies design criteria for pluripotent stem cell screens. Plos One. 4: e6438. PMID 19649273 DOI: 10.1371/journal.pone.0006438  1
2009 Kirouac DC, Madlambayan GJ, Yu M, Sykes EA, Ito C, Zandstra PW. Cell-cell interaction networks regulate blood stem and progenitor cell fate. Molecular Systems Biology. 5: 293. PMID 19638974 DOI: 10.1038/msb.2009.49  1
2009 Discher DE, Mooney DJ, Zandstra PW. Growth factors, matrices, and forces combine and control stem cells. Science (New York, N.Y.). 324: 1673-7. PMID 19556500 DOI: 10.1126/science.1171643  1
2009 Csaszar E, Gavigan G, Ungrin M, Thérien C, Dubé P, Féthière J, Sauvageau G, Roy DC, Zandstra PW. An automated system for delivery of an unstable transcription factor to hematopoietic stem cell cultures. Biotechnology and Bioengineering. 103: 402-12. PMID 19266473 DOI: 10.1002/bit.22297  1
2009 Ellis J, Bruneau BG, Keller G, Lemischka IR, Nagy A, Rossant J, Srivastava D, Zandstra PW, Stanford WL. Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell. 4: 198-9; author reply . PMID 19265656 DOI: 10.1016/j.stem.2009.02.010  1
2009 Zandstra PW. Pairing cells to enhance fusion. Nature Methods. 6: 123-4. PMID 19180092 DOI: 10.1038/nmeth0209-123  1
2009 Peerani R, Bauwens C, Kumacheva E, Zandstra PW. Patterning mouse and human embryonic stem cells using micro-contact printing. Methods in Molecular Biology (Clifton, N.J.). 482: 21-33. PMID 19089347 DOI: 10.1007/978-1-59745-060-7_2  1
2009 Niebruegge S, Bauwens CL, Peerani R, Thavandiran N, Masse S, Sevaptisidis E, Nanthakumar K, Woodhouse K, Husain M, Kumacheva E, Zandstra PW. Generation of human embryonic stem cell-derived mesoderm and cardiac cells using size-specified aggregates in an oxygen-controlled bioreactor. Biotechnology and Bioengineering. 102: 493-507. PMID 18767184 DOI: 10.1002/bit.22065  1
2008 Kirouac DC, Zandstra PW. The systematic production of cells for cell therapies. Cell Stem Cell. 3: 369-81. PMID 18940729 DOI: 10.1016/j.stem.2008.09.001  1
2008 Purpura KA, George SH, Dang SM, Choi K, Nagy A, Zandstra PW. Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner. Stem Cells (Dayton, Ohio). 26: 2832-42. PMID 18772315 DOI: 10.1634/stemcells.2008-0237  1
2008 Coles-Takabe BL, Brain I, Purpura KA, Karpowicz P, Zandstra PW, Morshead CM, van der Kooy D. Don't look: growing clonal versus nonclonal neural stem cell colonies. Stem Cells (Dayton, Ohio). 26: 2938-44. PMID 18757294 DOI: 10.1634/stemcells.2008-0558  1
2008 Tanaka TS, Davey RE, Lan Q, Zandstra PW, Stanford WL. Development of a gene-trap vector with a highly sensitive fluorescent protein reporter system for expression profiling. Genesis (New York, N.Y. : 2000). 46: 347-56. PMID 18615730 DOI: 10.1002/dvg.20404  1
2008 Bauwens CL, Peerani R, Niebruegge S, Woodhouse KA, Kumacheva E, Husain M, Zandstra PW. Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories. Stem Cells (Dayton, Ohio). 26: 2300-10. PMID 18583540 DOI: 10.1634/stemcells.2008-0183  1
2008 Varelas X, Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J, Yaffe MB, Zandstra PW, Wrana JL. TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. Nature Cell Biology. 10: 837-48. PMID 18568018 DOI: 10.1038/ncb1748  1
2008 Alberti K, Davey RE, Onishi K, George S, Salchert K, Seib FP, Bornhäuser M, Pompe T, Nagy A, Werner C, Zandstra PW. Functional immobilization of signaling proteins enables control of stem cell fate. Nature Methods. 5: 645-50. PMID 18552855 DOI: 10.1038/nmeth.1222  1
2008 Purpura KA, Morin J, Zandstra PW. Analysis of the temporal and concentration-dependent effects of BMP-4, VEGF, and TPO on development of embryonic stem cell-derived mesoderm and blood progenitors in a defined, serum-free media. Experimental Hematology. 36: 1186-98. PMID 18550259 DOI: 10.1016/j.exphem.2008.04.003  1
2008 Fromstein JD, Zandstra PW, Alperin C, Rockwood D, Rabolt JF, Woodhouse KA. Seeding bioreactor-produced embryonic stem cell-derived cardiomyocytes on different porous, degradable, polyurethane scaffolds reveals the effect of scaffold architecture on cell morphology. Tissue Engineering. Part A. 14: 369-78. PMID 18333789 DOI: 10.1089/tea.2006.0410  1
2008 Ungrin MD, Joshi C, Nica A, Bauwens C, Zandstra PW. Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates. Plos One. 3: e1565. PMID 18270562 DOI: 10.1371/journal.pone.0001565  1
2008 Wang W, Horner DN, Chen WL, Zandstra PW, Audet J. Synergy between erythropoietin and stem cell factor during erythropoiesis can be quantitatively described without co-signaling effects. Biotechnology and Bioengineering. 99: 1261-72. PMID 17969148 DOI: 10.1002/bit.21677  1
2007 Ungrin M, O'Connor M, Eaves C, Zandstra PW. Phenotypic analysis of human embryonic stem cells. Current Protocols in Stem Cell Biology. Unit 1B.3. PMID 18785161 DOI: 10.1002/9780470151808.sc01b03s2  1
2007 Walker E, Ohishi M, Davey RE, Zhang W, Cassar PA, Tanaka TS, Der SD, Morris Q, Hughes TR, Zandstra PW, Stanford WL. Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment. Cell Stem Cell. 1: 71-86. PMID 18371337 DOI: 10.1016/j.stem.2007.04.002  1
2007 Peerani R, Rao BM, Bauwens C, Yin T, Wood GA, Nagy A, Kumacheva E, Zandstra PW. Niche-mediated control of human embryonic stem cell self-renewal and differentiation. The Embo Journal. 26: 4744-55. PMID 17948051 DOI: 10.1038/sj.emboj.7601896  1
2007 Mahdavi A, Davey RE, Bhola P, Yin T, Zandstra PW. Sensitivity analysis of intracellular signaling pathway kinetics predicts targets for stem cell fate control. Plos Computational Biology. 3: e130. PMID 17616983 DOI: 10.1371/journal.pcbi.0030130  1
2007 Baksh D, Zandstra PW, Davies JE. A non-contact suspension culture approach to the culture of osteogenic cells derived from a CD49elow subpopulation of human bone marrow-derived cells. Biotechnology and Bioengineering. 98: 1195-208. PMID 17614333 DOI: 10.1002/bit.21556  1
2007 Alperin C, Zandstra PW, Woodhouse KA. Engineering cardiac healing using embryonic stem cell-derived cardiac cell seeded constructs. Frontiers in Bioscience : a Journal and Virtual Library. 12: 3694-712. PMID 17485332 DOI: 10.2741/2345  1
2007 Davey RE, Onishi K, Mahdavi A, Zandstra PW. LIF-mediated control of embryonic stem cell self-renewal emerges due to an autoregulatory loop. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2020-32. PMID 17356004 DOI: 10.1096/fj.06-7852com  1
2006 Madlambayan GJ, Rogers I, Purpura KA, Ito C, Yu M, Kirouac D, Casper RF, Zandstra PW. Clinically relevant expansion of hematopoietic stem cells with conserved function in a single-use, closed-system bioprocess. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 12: 1020-30. PMID 17084368 DOI: 10.1016/j.bbmt.2006.07.005  1
2006 Kirouac DC, Zandstra PW. Understanding cellular networks to improve hematopoietic stem cell expansion cultures. Current Opinion in Biotechnology. 17: 538-47. PMID 16899360 DOI: 10.1016/j.copbio.2006.07.003  1
2006 Davey RE, Zandstra PW. Spatial organization of embryonic stem cell responsiveness to autocrine gp130 ligands reveals an autoregulatory stem cell niche. Stem Cells (Dayton, Ohio). 24: 2538-48. PMID 16825607 DOI: 10.1634/stemcells.2006-0216  1
2005 Madlambayan GJ, Rogers I, Kirouac DC, Yamanaka N, Mazurier F, Doedens M, Casper RF, Dick JE, Zandstra PW. Dynamic changes in cellular and microenvironmental composition can be controlled to elicit in vitro human hematopoietic stem cell expansion. Experimental Hematology. 33: 1229-39. PMID 16219546 DOI: 10.1016/j.exphem.2005.05.018  1
2005 Rao BM, Zandstra PW. Culture development for human embryonic stem cell propagation: Molecular aspects and challenges Current Opinion in Biotechnology. 16: 568-576. PMID 16099157 DOI: 10.1016/j.copbio.2005.08.001  1
2005 Fok EY, Zandstra PW. Shear-controlled single-step mouse embryonic stem cell expansion and embryoid body-based differentiation. Stem Cells (Dayton, Ohio). 23: 1333-42. PMID 16081660 DOI: 10.1634/stemcells.2005-0112  1
2005 Baksh D, Davies JE, Zandstra PW. Soluble factor cross-talk between human bone marrow-derived hematopoietic and mesenchymal cells enhances in vitro CFU-F and CFU-O growth and reveals heterogeneity in the mesenchymal progenitor cell compartment. Blood. 106: 3012-9. PMID 16030193 DOI: 10.1182/blood-2005-01-0433  1
2005 Alperin C, Zandstra PW, Woodhouse KA. Polyurethane films seeded with embryonic stem cell-derived cardiomyocytes for use in cardiac tissue engineering applications. Biomaterials. 26: 7377-86. PMID 16023195 DOI: 10.1016/j.biomaterials.2005.05.064  1
2005 Viswanathan S, Davey RE, Cheng D, Raghu RC, Lauffenburger DA, Zandstra PW. Clonal evolution of stem and differentiated cells can be predicted by integrating cell-intrinsic and -extrinsic parameters. Biotechnology and Applied Biochemistry. 42: 119-31. PMID 15882145 DOI: 10.1042/BA20040207  1
2005 Bauwens C, Yin T, Dang S, Peerani R, Zandstra PW. Development of a perfusion fed bioreactor for embryonic stem cell-derived cardiomyocyte generation: oxygen-mediated enhancement of cardiomyocyte output. Biotechnology and Bioengineering. 90: 452-61. PMID 15778986 DOI: 10.1002/bit.20445  1
2005 Dang SM, Zandstra PW. Scalable production of embryonic stem cell-derived cells. Methods in Molecular Biology (Clifton, N.J.). 290: 353-64. PMID 15361674  1
2004 Chang KH, Zandstra PW. Quantitative screening of embryonic stem cell differentiation: endoderm formation as a model. Biotechnology and Bioengineering. 88: 287-98. PMID 15486933 DOI: 10.1002/bit.20242  1
2004 Zandstra PW. The opportunity of stem cell bioengineering. Biotechnology and Bioengineering. 88: 263. PMID 15486929 DOI: 10.1002/bit.20303  1
2004 Davey RE, Zandstra PW. Signal processing underlying extrinsic control of stem cell fate. Current Opinion in Hematology. 11: 95-101. PMID 15257025 DOI: 10.1097/01.moh.0000133650.68744.0c  1
2004 Dang SM, Gerecht-Nir S, Chen J, Itskovitz-Eldor J, Zandstra PW. Controlled, scalable embryonic stem cell differentiation culture. Stem Cells (Dayton, Ohio). 22: 275-82. PMID 15153605 DOI: 10.1634/stemcells.22-3-275  1
2004 Purpura KA, Aubin JE, Zandstra PW. Sustained in vitro expansion of bone progenitors is cell density dependent. Stem Cells (Dayton, Ohio). 22: 39-50. PMID 14688390 DOI: 10.1634/stemcells.22-1-39  1
2004 Madlambayan GJ, Baksh D, Zandstra PW. Systematic Approach to the Development of Stem Cell Expansion Cultures Handbook of Stem Cells. 2: 663-676. DOI: 10.1016/B978-012436643-5/50149-8  1
2004 Alperin C, Zandstra PW, Bauwens C, Woodhouse KA. Embryonic stem cell-derived cardiomyocytes cultured on biodegradable polyurethane scaffolds Transactions - 7th World Biomaterials Congress. 471.  1
2003 Viswanathan S, Zandstra PW. Towards predictive models of stem cell fate. Cytotechnology. 41: 75-92. PMID 19002945 DOI: 10.1023/A:1024866504538  1
2003 Viswanathan S, Benatar T, Mileikovsky M, Lauffenburger DA, Nagy A, Zandstra PW. Supplementation-dependent differences in the rates of embryonic stem cell self-renewal, differentiation, and apoptosis. Biotechnology and Bioengineering. 84: 505-17. PMID 14574685 DOI: 10.1002/bit.10799  1
2003 Zandstra PW, Bauwens C, Yin T, Liu Q, Schiller H, Zweigerdt R, Pasumarthi KBS, Field LJ. Scalable production of embryonic stem cell-derived cardiomyocytes Tissue Engineering. 9: 767-778. PMID 13678453 DOI: 10.1089/107632703768247449  1
2003 Purpura KA, Zandstra PW, Aubin JE. Fluorescence activated cell sorting reveals heterogeneous and cell non-autonomous osteoprogenitor differentiation in fetal rat calvaria cell populations. Journal of Cellular Biochemistry. 90: 109-20. PMID 12938161 DOI: 10.1002/jcb.10596  1
2003 Baksh D, Davies JE, Zandstra PW. Adult human bone marrow-derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion. Experimental Hematology. 31: 723-32. PMID 12901978 DOI: 10.1016/S0301-472X(03)00106-1  1
2003 Purpura KA, Aubin JE, Zandstra PW. Two-color image analysis discriminates between mineralized and unmineralized bone nodules in vitro. Biotechniques. 34: 1188-92, 1194, 1196 . PMID 12813887  1
2002 Madras N, Gibbs AL, Zhou Y, Zandstra PW, Aubin JE. Modeling stem cell development by retrospective analysis of gene expression profiles in single progenitor-derived colonies. Stem Cells (Dayton, Ohio). 20: 230-40. PMID 12004081 DOI: 10.1634/stemcells.20-3-230  1
2002 Dang SM, Kyba M, Perlingeiro R, Daley GQ, Zandstra PW. Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems. Biotechnology and Bioengineering. 78: 442-53. PMID 11948451 DOI: 10.1002/bit.10220  1
2002 Viswanathan S, Benatar T, Rose-John S, Lauffenburger DA, Zandstra PW. Ligand/receptor signaling threshold (LIST) model accounts for gp130-mediated embryonic stem cell self-renewal responses to LIF and HIL-6. Stem Cells (Dayton, Ohio). 20: 119-38. PMID 11897869 DOI: 10.1634/stemcells.20-2-119  1
2002 Bauwens C, Yin T, Liu Q, Zandstra PW. Scalable generation of cardiomyocytes from mouse embryonic stem cells Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 745.  1
2002 Madlambayan GJ, Baksh D, Rogers I, Casper RF, Davies JE, Zandstra PW. Manipulation of adult bone marrow derived stem and progenitor cell population dynamics in suspension culture Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 881.  1
2001 Madlambayan GJ, Rogers I, Casper RF, Zandstra PW. Controlling culture dynamics for the expansion of hematopoietic stem cells. Journal of Hematotherapy & Stem Cell Research. 10: 481-92. PMID 11522231 DOI: 10.1089/15258160152509091  1
2001 Zandstra PW, Nagy A. Stem cell bioengineering Annual Review of Biomedical Engineering. 3: 275-305. PMID 11447065 DOI: 10.1146/annurev.bioeng.3.1.275  1
2000 Zandstra PW, Lauffenburger DA, Eaves CJ. A ligand-receptor signaling threshold model of stem cell differentiation control: A biologically conserved mechanism applicable to hematopoiesis Blood. 96: 1215-1222. PMID 10942360  1
2000 Zandstra PW, Le HV, Daley GQ, Griffith LG, Lauffenburger DA. Leukemia inhibitory factor (LIF) concentration modulates embryonic stem cell self-renewal and differentiation independently of proliferation. Biotechnology and Bioengineering. 69: 607-17. PMID 10918135 DOI: 10.1002/1097-0290(20000920)69:6<607::AID-BIT4>3.0.CO;2-F  1
2000 Viswanathan S, Benatar TC, Rose-John S, Lauffenburger DA, Zandstra PW. Threshold-dependent regulation of stem cell fate: a developmentally conserved mechanism applicable to hematopoiesis Blood. 96.  1
1999 Zandstra PW, Jervis E, Haynes CA, Kilburn DG, Eaves CJ, Piret JM. Concentration-dependent internalization of a cytokine/cytokine receptor complex in human hematopoietic cells. Biotechnology and Bioengineering. 63: 493-501. PMID 10099630 DOI: 10.1002/(SICI)1097-0290(19990520)63:4<493::AID-BIT13>3.0.CO;2-0  1
1998 Zandstra PW, Conneally E, Piret JM, Eaves CJ. Ontogeny-associated changes in the cytokine responses of primitive human haemopoietic cells. British Journal of Haematology. 101: 770-8. PMID 9674754 DOI: 10.1046/j.1365-2141.1998.00777.x  1
1998 Audet J, Zandstra PW, Eaves CJ, Piret JM. Advances in hematopoietic stem cell culture. Current Opinion in Biotechnology. 9: 146-51. PMID 9588003 DOI: 10.1016/S0958-1669(98)80107-9  1
1998 Petzer AL, Conneally E, Zandstra PW, Cashman JD, Gastl G, Eaves AC, Eaves CJ. In vitro expansion of primitive progenitors (LTC-IC, CRU) under defined culture conditions Bone Marrow Transplantation. 22.  1
1997 Zandstra PW, Conneally E, Petzer AL, Piret JM, Eaves CJ. Cytokine manipulation of primitive human hematopoietic cell self-renewal. Proceedings of the National Academy of Sciences of the United States of America. 94: 4698-703. PMID 9114054 DOI: 10.1073/pnas.94.9.4698  1
1997 Zandstra PW, Petzer AL, Eaves CJ, Piret JM. Cellular determinants affecting the rate of cytokine depletion in cultures of human hematopoietic cells Biotechnology and Bioengineering. 54: 58-66. DOI: 10.1002/(SICI)1097-0290(19970405)54:1<58::AID-BIT7>3.0.CO;2-X  1
1997 Zandstra PW, Conneallv E, Piret JM, Eaves CJ. Changes during ontogeny in the cytokine responsiveness of human erythroid, myeloid and ltcic progenitors Experimental Hematology. 25: 877.  1
1996 Petzer AL, Zandstra PW, Piret JM, Eaves CJ. Differential cytokine effects on primitive (CD34+CD38-) human hematopoietic cells: novel responses to Flt3-ligand and thrombopoietin. The Journal of Experimental Medicine. 183: 2551-8. PMID 8676076 DOI: 10.1084/jem.183.6.2551  1
1994 Zandstra PW, Eaves CJ, Piret JM. Expansion of hematopoietic progenitor cell populations in stirred suspension bioreactors of normal human bone marrow cells. Bio/Technology (Nature Publishing Company). 12: 909-14. PMID 7521647 DOI: 10.1038/nbt0994-909  1
1992 Helle SS, Zandstra PW, Cooper DG. Unusual surface tension behavior of an aqueous solution of gramicidin S Journal of Colloid and Interface Science. 151: 130-135. DOI: 10.1016/0021-9797(92)90243-F  1
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