Peter L. Carlen - Publications

Affiliations: 
Biomedical Engineering University of Toronto, Toronto, ON, Canada 
Area:
Biomedical Engineering, Neuroscience Biology

256 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Chang M, Dufour S, Carlen PL, Valiante TA. Generation and On-Demand Initiation of Acute Ictal Activity in Rodent and Human Tissue. Journal of Visualized Experiments : Jove. PMID 30735161 DOI: 10.3791/57952  0.92
2019 Gondard E, Teves L, Wang L, McKinnon C, Hamani C, Kalia SK, Carlen PL, Tymianski M, Lozano AM. Deep Brain Stimulation rescues memory and synaptic activity in a rat model of global ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30696731 DOI: 10.1523/JNEUROSCI.1222-18.2019  0.4
2018 Song H, Mylvaganam SM, Wang J, Mylvaganam SMK, Wu C, Carlen PL, Eubanks JH, Feng J, Zhang L. Contributions of the Hippocampal CA3 Circuitry to Acute Seizures and Hyperexcitability Responses in Mouse Models of Brain Ischemia. Frontiers in Cellular Neuroscience. 12: 278. PMID 30210302 DOI: 10.3389/fncel.2018.00278  0.76
2018 Jacobs D, Hilton T, Del Campo M, Carlen PL, Bardakjian BL. Classification of Pre-Clinical Seizure States using Scalp EEG Cross-Frequency Coupling Features. Ieee Transactions On Bio-Medical Engineering. PMID 29993471 DOI: 10.1109/TBME.2018.2797919  0.68
2017 Chang M, Dian JA, Dufour S, Wang L, Moradi-Chameh H, Ramani M, Zhang L, Carlen PL, Womelsdorf T, Valiante TA. Brief activation of GABAergic interneurons initiates the transition to ictal events through post-inhibitory rebound excitation. Neurobiology of Disease. PMID 29024712 DOI: 10.1016/j.nbd.2017.10.007  0.92
2017 Salam MT, Montandon G, Genov R, Devinsky O, Del Campo M, Carlen PL. Mortality with brainstem seizures from focal 4-aminopyridine-induced recurrent hippocampal seizures. Epilepsia. PMID 28691204 DOI: 10.1111/epi.13846  0.44
2017 Ringuette D, Jeffrey MA, Dufour S, Carlen PL, Levi O. Continuous multi-modality brain imaging reveals modified neurovascular seizure response after intervention. Biomedical Optics Express. 8: 873-889. PMID 28270990 DOI: 10.1364/BOE.8.000873  0.6
2016 Li C, Jacobs D, Hilton T, Campo MD, Chinvarun Y, Carlen PL, Bardakjian BL. Epileptogenic Source Imaging Using Cross-Frequency Coupled Signals From Scalp EEG. Ieee Transactions On Bio-Medical Engineering. 63: 2607-2618. PMID 27875126 DOI: 10.1109/TBME.2016.2613936  0.68
2016 Machado R, Soltani N, Dufour S, Salam MT, Carlen PL, Genov R, Thompson M. Biofouling-Resistant Impedimetric Sensor for Array High-Resolution Extracellular Potassium Monitoring in the Brain. Biosensors. 6. PMID 27754393 DOI: 10.3390/bios6040053  0.6
2016 Wang L, Dufour S, Valiante TA, Carlen PL. Extracellular Potassium and Seizures: Excitation, Inhibition and the Role of Ih. International Journal of Neural Systems. 1650044. PMID 27464853 DOI: 10.1142/S0129065716500441  1
2016 Krawczyk M, Ramani M, Dian J, Florez CM, Mylvaganam S, Brien J, Reynolds J, Kapur B, Zoidl G, Poulter MO, Carlen PL. Hippocampal Hyperexcitability in Fetal Alcohol Spectrum Disorder: Pathological Sharp Waves and Excitatory/Inhibitory Synaptic Imbalance. Experimental Neurology. PMID 26996134 DOI: 10.1016/j.expneurol.2016.03.013  0.48
2016 Ramani M, Mylvaganam S, Krawczyk M, Wang L, Zoidl C, Brien J, Reynolds JN, Kapur B, Poulter MO, Zoidl G, Carlen PL. Differential expression of astrocytic connexins in a mouse model of prenatal alcohol exposure. Neurobiology of Disease. PMID 26951949 DOI: 10.1016/j.nbd.2016.02.022  1
2016 Jalini S, Ye H, Tonkikh AA, Charlton MP, Carlen PL. Raised Intracellular Calcium Contributes to Ischemia-Induced Depression of Evoked Synaptic Transmission. Plos One. 11: e0148110. PMID 26934214 DOI: 10.1371/journal.pone.0148110  1
2016 Cotic M, Chinvarun Y, Del Campo M, Carlen PL, Bardakjian BL. Spatial Coherence Profiles of Ictal High-Frequency Oscillations Correspond to Those of Interictal Low-Frequency Oscillations in the ECoG of Epileptic Patients. Ieee Transactions On Bio-Medical Engineering. 63: 76-85. PMID 25561587 DOI: 10.1109/TBME.2014.2386791  1
2015 Krawczyk M, Ramani M, Mylvaganam S, Carlen PL. REMOVED: Pathological sharp waves and hyperexcitability in a mouse model of Fetal Alcohol Spectrum Disorder (FASD). International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 14. PMID 29887055 DOI: 10.1016/j.ijdevneu.2015.04.049  0.4
2015 Dian JA, Colic S, Chinvarun Y, Carlen PL, Bardakjian BL. Identification of brain regions of interest for epilepsy surgery planning using support vector machines. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2015: 6590-3. PMID 26737803 DOI: 10.1109/EMBC.2015.7319903  1
2015 Guirgis M, Chinvarun Y, Del Campo M, Carlen PL, Bardakjian BL. Defining regions of interest using cross-frequency coupling in extratemporal lobe epilepsy patients. Journal of Neural Engineering. 12: 026011. PMID 25768723 DOI: 10.1088/1741-2560/12/2/026011  1
2015 Cotic M, Zalay OC, Chinvarun Y, del Campo M, Carlen PL, Bardakjian BL. Mapping the coherence of ictal high frequency oscillations in human extratemporal lobe epilepsy. Epilepsia. 56: 393-402. PMID 25630492 DOI: 10.1111/epi.12918  1
2015 Shulyzki R, Abdelhalim K, Bagheri A, Salam MT, Florez CM, Velazquez JL, Carlen PL, Genov R. 320-channel active probe for high-resolution neuromonitoring and responsive neurostimulation. Ieee Transactions On Biomedical Circuits and Systems. 9: 34-49. PMID 25486647 DOI: 10.1109/TBCAS.2014.2312552  1
2015 Bazzigaluppi P, Dufour S, Carlen PL. Wide field fluorescent imaging of extracellular spatiotemporal potassium dynamics in vivo. Neuroimage. 104: 110-6. PMID 25312775 DOI: 10.1016/j.neuroimage.2014.10.012  1
2014 Cotic M, Chinvarun Y, Guirgis M, Carlen PL, Bardakjian BL. Gamma (30-80Hz) bicoherence distinguishes seizures in the human epileptic brain. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2014: 4455-8. PMID 25570981 DOI: 10.1109/EMBC.2014.6944613  1
2014 Goncharenko K, Eftekharpour E, Velumian AA, Carlen PL, Fehlings MG. Changes in gap junction expression and function following ischemic injury of spinal cord white matter. Journal of Neurophysiology. 112: 2067-75. PMID 25080569 DOI: 10.1152/jn.00037.2013  1
2014 Gabran SR, Salam MT, Dian J, El-Hayek Y, Perez Velazquez JL, Genov R, Carlen PL, Salama MM, Mansour RR. 3-D flexible nano-textured high-density microelectrode arrays for high-performance neuro-monitoring and neuro-stimulation. Ieee Transactions On Neural Systems and Rehabilitation Engineering : a Publication of the Ieee Engineering in Medicine and Biology Society. 22: 1072-82. PMID 24876130 DOI: 10.1109/TNSRE.2014.2322077  1
2014 Mylvaganam S, Ramani M, Krawczyk M, Carlen PL. Roles of gap junctions, connexins, and pannexins in epilepsy. Frontiers in Physiology. 5: 172. PMID 24847276 DOI: 10.3389/fphys.2014.00172  1
2014 Yin Y, Middleton WJ, Florez CM, Carlen PL, Hossam EB. Propofol enhances the field excitatory postsynaptic potentials in CA1 hippocampal slices of young and aged mice. Chinese Medical Journal. 127: 137-41. PMID 24384439 DOI: 10.3760/cma.j.issn.0366-6999.20131442  1
2014 Guirgis M, Serletis D, Zhang J, Florez C, Dian JA, Carlen PL, Bardakjian BL. Classification of Multiple Seizure-Like States in Three Different Rodent Models of Epileptogenesis. Ieee Transactions On Neural Systems and Rehabilitation Engineering : a Publication of the Ieee Engineering in Medicine and Biology Society. 22: 21-32. PMID 23771347 DOI: 10.1109/TNSRE.2013.2267543  1
2014 Valiante TA, Carlen PL. Electrophysiological Mechanisms of Network Control: Bursting in the Brain-From Cells to Networks Neuronal Networks in Brain Function, Cns Disorders, and Therapeutics. 121-133. DOI: 10.1016/B978-0-12-415804-7.00009-5  1
2013 Maheandiran M, Mylvaganam S, Wu C, El-Hayek Y, Sugumar S, Hazrati L, del Campo M, Giacca A, Zhang L, Carlen PL. Severe hypoglycemia in a juvenile diabetic rat model: presence and severity of seizures are associated with mortality. Plos One. 8: e83168. PMID 24386156 DOI: 10.1371/journal.pone.0083168  0.76
2013 Gabran SR, Salam MT, Dian J, El-Hayek Y, Perez Velazquez JL, Genov R, Carlen PL, Salama MM, Mansour RR. High-density intracortical microelectrode arrays with multiple metallization layers for fine-resolution neuromonitoring and neurostimulation. Ieee Transactions On Neural Systems and Rehabilitation Engineering : a Publication of the Ieee Engineering in Medicine and Biology Society. 21: 869-79. PMID 24122564 DOI: 10.1109/TNSRE.2013.2279403  1
2013 Guirgis M, Chinvarun Y, Carlen PL, Bardakjian BL. The role of delta-modulated high frequency oscillations in seizure state classification. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2013: 6595-8. PMID 24111254 DOI: 10.1109/EMBC.2013.6611067  1
2013 Cotic M, Zalay O, Carlen PL, Chinvarun Y, Bardakjian BL. Synchrony of high frequency oscillations in the human epileptic brain. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2013: 5582-5. PMID 24111002 DOI: 10.1109/EMBC.2013.6610815  1
2013 El-Hayek YH, Wu C, Ye H, Wang J, Carlen PL, Zhang L. Hippocampal excitability is increased in aged mice. Experimental Neurology. 247: 710-9. PMID 23510762 DOI: 10.1016/j.expneurol.2013.03.012  1
2013 Serletis D, Carlen PL, Valiante TA, Bardakjian BL. Phase synchronization of neuronal noise in mouse hippocampal epileptiform dynamics. International Journal of Neural Systems. 23: 1250033. PMID 23273129 DOI: 10.1142/S0129065712500335  1
2013 Sutton AC, Yu W, Calos ME, Mueller LE, Berk M, Shim J, Molho ES, Brotchie JM, Carlen PL, Shin DS. Elevated potassium provides an ionic mechanism for deep brain stimulation in the hemiparkinsonian rat. The European Journal of Neuroscience. 37: 231-41. PMID 23121286 DOI: 10.1111/ejn.12040  1
2012 Serletis D, Bardakjian BL, Valiante TA, Carlen PL. Complexity and multifractality of neuronal noise in mouse and human hippocampal epileptiform dynamics. Journal of Neural Engineering. 9: 056008. PMID 22929878 DOI: 10.1088/1741-2560/9/5/056008  1
2012 Kang EE, Zalay OC, Serletis D, Carlen PL, Bardakjian BL. Markers of pathological excitability derived from principal dynamic modes of hippocampal neurons. Journal of Neural Engineering. 9: 056004. PMID 22871606 DOI: 10.1088/1741-2560/9/5/056004  1
2012 Carlen PL. Curious and contradictory roles of glial connexins and pannexins in epilepsy. Brain Research. 1487: 54-60. PMID 22796594 DOI: 10.1016/j.brainres.2012.06.059  1
2012 Abdelmalik PA, Politzer N, Carlen PL. Magnesium as an effective adjunct therapy for drug resistant seizures. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 39: 323-7. PMID 22547512  1
2012 Zhang ZJ, Koifman J, Shin DS, Ye H, Florez CM, Zhang L, Valiante TA, Carlen PL. Transition to seizure: ictal discharge is preceded by exhausted presynaptic GABA release in the hippocampal CA3 region. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2499-512. PMID 22396423 DOI: 10.1523/JNEUROSCI.4247-11.2012  0.92
2012 Ye H, Cotic M, Fehlings MG, Carlen PL. Influence of cellular properties on the electric field distribution around a single cell Progress in Electromagnetics Research B. 141-161.  1
2011 Kang EE, Zalay OC, El Beheiry H, Wong J, del Campo M, Carlen PL, Bardakijan BL. Spectral features of electroencephalogram in characterizing various brain states under anesthesia. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 3099-102. PMID 22254995 DOI: 10.1109/IEMBS.2011.6090846  1
2011 Guirgis M, Serletis D, Carlen PL, Bardakjian BL. Capturing the state transitions of seizure-like events using Hidden Markov models. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 2061-4. PMID 22254742 DOI: 10.1109/IEMBS.2011.6090381  1
2011 Cotic M, Zalay O, Valiante T, Carlen PL, Bardakjian BL. Frequency interactions in human epileptic brain. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 2057-60. PMID 22254741 DOI: 10.1109/IEMBS.2011.6090380  1
2011 Zhang ZJ, Valiante TA, Carlen PL. Transition to seizure: From " macro" - to " micro" -mysteries Epilepsy Research. 97: 290-299. PMID 22075227 DOI: 10.1016/j.eplepsyres.2011.09.025  1
2011 Shin DS, Yu W, Sutton A, Calos M, Puil E, Carlen PL. Isovaline, a rare amino acid, has anticonvulsant properties in two in vitro hippocampal seizure models by increasing interneuronal activity. Epilepsia. 52: 2084-93. PMID 21906050 DOI: 10.1111/j.1528-1167.2011.03260.x  1
2011 Cotic M, Chiu AW, Jahromi SS, Carlen PL, Bardakjian BL. Common time-frequency analysis of local field potential and pyramidal cell activity in seizure-like events of the rat hippocampus. Journal of Neural Engineering. 8: 046024. PMID 21712570 DOI: 10.1088/1741-2560/8/4/046024  1
2011 El-Hayek YH, Wu C, Chen R, Al-Sharif AR, Huang S, Patel N, Du C, Ruff CA, Fehlings MG, Carlen PL, Zhang L. Acute postischemic seizures are associated with increased mortality and brain damage in adult mice. Cerebral Cortex (New York, N.Y. : 1991). 21: 2863-75. PMID 21531782 DOI: 10.1093/cercor/bhr080  1
2011 Chiu AW, Derchansky M, Cotic M, Carlen PL, Turner SO, Bardakjian BL. Wavelet-based Gaussian-mixture hidden Markov model for the detection of multistage seizure dynamics: a proof-of-concept study. Biomedical Engineering Online. 10: 29. PMID 21504608 DOI: 10.1186/1475-925X-10-29  1
2011 Serletis D, Zalay OC, Valiante TA, Bardakjian BL, Carlen PL. Complexity in neuronal noise depends on network interconnectivity. Annals of Biomedical Engineering. 39: 1768-78. PMID 21347547 DOI: 10.1007/s10439-011-0281-x  1
2011 Shin DS, Yu W, Sutton A, Calos M, Carlen PL. Elevated potassium elicits recurrent surges of large GABAA-receptor-mediated post-synaptic currents in hippocampal CA3 pyramidal neurons. Journal of Neurophysiology. 105: 1185-98. PMID 21209355 DOI: 10.1152/jn.00770.2010  1
2011 Ye H, Cotic M, Fehlings MG, Carlen PL. Transmembrane potential generated by a magnetically induced transverse electric field in a cylindrical axonal model. Medical & Biological Engineering & Computing. 49: 107-19. PMID 21063912 DOI: 10.1007/s11517-010-0704-0  1
2011 Bell SH, Reynolds JN, Carlen PL. Response to Dr. Karp's Letter to the Editor Alcoholism: Clinical and Experimental Research. 35: 1019. DOI: 10.1111/j.1530-0277.2011.01538.x  1
2011 Fomani AA, Mansour RR, Florez-Quenguan CM, Carlen PL. Development and characterization of multisite three-dimensional microprobes for deep brain stimulation and recording Journal of Microelectromechanical Systems. 20: 1109-1118. DOI: 10.1109/JMEMS.2011.2160934  1
2010 Shahrokhi F, Abdelhalim K, Serletis D, Carlen PL, Genov R. The 128-channel fully differential digital integrated neural recording and stimulation interface. Ieee Transactions On Biomedical Circuits and Systems. 4: 149-61. PMID 23853339 DOI: 10.1109/TBCAS.2010.2041350  0.52
2010 Hamani C, Dubiela FP, Soares JC, Shin D, Bittencourt S, Covolan L, Carlen PL, Laxton AW, Hodaie M, Stone SS, Ha Y, Hutchison WD, Lozano AM, Mello LE, Oliveira MG. Anterior thalamus deep brain stimulation at high current impairs memory in rats. Experimental Neurology. 225: 154-62. PMID 20558163 DOI: 10.1016/j.expneurol.2010.06.007  1
2010 Zalay OC, Serletis D, Carlen PL, Bardakjian BL. System characterization of neuronal excitability in the hippocampus and its relevance to observed dynamics of spontaneous seizure-like transitions. Journal of Neural Engineering. 7: 036002. PMID 20404398 DOI: 10.1088/1741-2560/7/3/036002  1
2010 Bell SH, Stade B, Reynolds JN, Rasmussen C, Andrew G, Hwang PA, Carlen PL. The remarkably high prevalence of epilepsy and seizure history in fetal alcohol spectrum disorders. Alcoholism, Clinical and Experimental Research. 34: 1084-9. PMID 20374205 DOI: 10.1111/j.1530-0277.2010.01184.x  1
2010 Shin DSH, Yu W, Fawcett A, Carlen PL. Characterizing the persistent CA3 interneuronal spiking activity in elevated extracellular potassium in the young rat hippocampus Brain Research. 1331: 39-50. PMID 20303341 DOI: 10.1016/j.brainres.2010.03.023  1
2010 Ye H, Cotic M, Kang EE, Fehlings MG, Carlen PL. Transmembrane potential induced on the internal organelle by a time-varying magnetic field: a model study. Journal of Neuroengineering and Rehabilitation. 7: 12. PMID 20170538 DOI: 10.1186/1743-0003-7-12  1
2010 Samoilova M, Weisspapir M, Abdelmalik P, Velumian AA, Carlen PL. Chronic in vitro ketosis is neuroprotective but not anti-convulsant. Journal of Neurochemistry. 113: 826-35. PMID 20163521 DOI: 10.1111/j.1471-4159.2010.06645.x  1
2010 Ye H, Jalini S, Zhang L, Charlton M, Carlen PL. Early ischemia enhances action potential-dependent, spontaneous glutamatergic responses in CA1 neurons Journal of Cerebral Blood Flow and Metabolism. 30: 555-565. PMID 19844238 DOI: 10.1038/jcbfm.2009.227  1
2010 Mylvaganam S, Zhang L, Wu C, Zhang ZJ, Samoilova M, Eubanks J, Carlen PL, Poulter MO. Hippocampal seizures alter the expression of the pannexin and connexin transcriptome. Journal of Neurochemistry. 112: 92-102. PMID 19840216 DOI: 10.1111/j.1471-4159.2009.06431.x  0.76
2010 Kang EE, Zalay OC, Cotic M, Carlen PL, Bardakjian BL. Transformation of neuronal modes associated with low-Mg2+/high-K+ conditions in an in vitro model of epilepsy. Journal of Biological Physics. 36: 95-107. PMID 19669427 DOI: 10.1007/s10867-009-9144-1  1
2010 Naus CC, Giaume C, Carlen PL. Gap Junction Abnormalities and Disorders of the Nervous System Encyclopedia of Neuroscience. 517-522. DOI: 10.1016/B978-008045046-9.01258-4  1
2009 Poochikian-Sarkissian S, Tai P, del Campo M, Andrade DM, Carlen PL, Valiante T, Wennberg RA. Patient awareness of seizures as documented in the epilepsy monitoring unit. Canadian Journal of Neuroscience Nursing. 31: 22-3. PMID 20085117  0.52
2009 Shahar E, Derchansky M, Carlen PL. The role of altered tissue osmolality on the characteristics and propagation of seizure activity in the intact isolated mouse hippocampus Clinical Neurophysiology. 120: 673-678. PMID 19299198 DOI: 10.1016/j.clinph.2009.01.014  1
2009 Tonkikh AA, Carlen PL. Impaired presynaptic cytosolic and mitochondrial calcium dynamics in aged compared to young adult hippocampal CA1 synapses ameliorated by calcium chelation Neuroscience. 159: 1300-1308. PMID 19215725 DOI: 10.1016/j.neuroscience.2008.12.057  1
2009 Zalay OC, Kang EE, Cotic M, Carlen PL, Bardakjian BL. A wavelet packet-based algorithm for the extraction of neural rhythms. Annals of Biomedical Engineering. 37: 595-613. PMID 19142729 DOI: 10.1007/s10439-008-9634-5  1
2009 Del Campo M, Abdelmalik PA, Wu CP, Carlen PL, Zhang L. Seizure-like activity in the hypoglycemic rat: lack of correlation with the electroencephalogram of free-moving animals. Epilepsy Research. 83: 243-8. PMID 19136235 DOI: 10.1016/j.eplepsyres.2008.11.012  0.76
2009 He J, Hsiang HL, Wu C, Mylvagnanam S, Carlen PL, Zhang L. Cellular mechanisms of cobalt-induced hippocampal epileptiform discharges. Epilepsia. 50: 99-115. PMID 18727680 DOI: 10.1111/j.1528-1167.2008.01767.x  0.76
2008 Shin DS, Carlen PL. Enhanced Ih depresses rat entopeduncular nucleus neuronal activity from high-frequency stimulation or raised Ke+ Journal of Neurophysiology. 99: 2203-2219. PMID 18305090 DOI: 10.1152/jn.01065.2007  1
2008 Samoilova M, Wentlandt K, Adamchik Y, Velumian AA, Carlen PL. Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypic hippocampal slice cultures. Experimental Neurology. 210: 762-75. PMID 18284929 DOI: 10.1016/j.expneurol.2008.01.005  1
2008 Feeney CJ, Frantseva MV, Carlen PL, Pennefather PS, Shulyakova N, Shniffer C, Mills LR. Vulnerability of glial cells to hydrogen peroxide in cultured hippocampal slices. Brain Research. 1198: 1-15. PMID 18261717 DOI: 10.1016/j.brainres.2007.12.049  1
2008 Abdelmalik PA, Liang P, Weisspapir M, Samoilova M, Burnham WM, Carlen PL. Factors which abolish hypoglycemic seizures do not increase cerebral glycogen content in vitro. Neurobiology of Disease. 29: 201-9. PMID 17919917 DOI: 10.1016/j.nbd.2007.08.009  1
2007 Saboory E, Derchansky M, Ismaili M, Jahromi SS, Brull R, Carlen PL, El Beheiry H. Mechanisms of morphine enhancement of spontaneous seizure activity. Anesthesia and Analgesia. 105: 1729-35, table of co. PMID 18042875 DOI: 10.1213/01.ane.0000287675.15225.0b  0.6
2007 Kapur BM, Vandenbroucke AC, Adamchik Y, Lehotay DC, Carlen PL. Formic acid, a novel metabolite of chronic ethanol abuse, causes neurotoxicity, which is prevented by folic acid. Alcoholism, Clinical and Experimental Research. 31: 2114-20. PMID 18034701 DOI: 10.1111/j.1530-0277.2007.00541.x  1
2007 Ye H, Cotic M, Carlen PL. Transmembrane potential induced in a spherical cell model under low-frequency magnetic stimulation. Journal of Neural Engineering. 4: 283-93. PMID 17873431 DOI: 10.1088/1741-2560/4/3/014  1
2007 Shin DS, Samoilova M, Cotic M, Zhang L, Brotchie JM, Carlen PL. High frequency stimulation or elevated K+ depresses neuronal activity in the rat entopeduncular nucleus. Neuroscience. 149: 68-86. PMID 17826920 DOI: 10.1016/j.neuroscience.2007.06.055  1
2007 El Beheiry H, Ouanounou A, Carlen PL. L-type calcium channel blockade modifies anesthetic actions on aged hippocampal neurons Neuroscience. 147: 117-126. PMID 17507168 DOI: 10.1016/j.neuroscience.2007.03.031  1
2007 Abdelmalik PA, Shannon P, Yiu A, Liang P, Adamchik Y, Weisspapir M, Samoilova M, Burnham WM, Carlen PL. Hypoglycemic seizures during transient hypoglycemia exacerbate hippocampal dysfunction. Neurobiology of Disease. 26: 646-60. PMID 17459717 DOI: 10.1016/j.nbd.2007.03.002  1
2007 Andrade DM, Carlen PL. Novel antiseizure drug mechanisms Future Neurology. 2: 73-86. DOI: 10.2217/14796708.2.1.73  1
2006 Aziz JN, Karakiewicz R, Genov R, Bardakjian BL, Derchansky M, Carlen PL. Towards real-time in-implant epileptic seizure prediction. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 5476-9. PMID 17947144 DOI: 10.1109/IEMBS.2006.259737  1
2006 Wentlandt K, Samoilova M, Carlen PL, El Beheiry H. General anesthetics inhibit gap junction communication in cultured organotypic hippocampal slices. Anesthesia and Analgesia. 102: 1692-8. PMID 16717311 DOI: 10.1213/01.ane.0000202472.41103.78  1
2006 Singer BH, Derchansky M, Carlen PL, Zochowski M. Lag synchrony measures dynamical processes underlying progression of seizure states. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 73: 021910. PMID 16605365 DOI: 10.1103/PhysRevE.73.021910  1
2006 Chiu AW, Jahromi SS, Khosravani H, Carlen PL, Bardakjian BL. The effects of high-frequency oscillations in hippocampal electrical activities on the classification of epileptiform events using artificial neural networks. Journal of Neural Engineering. 3: 9-20. PMID 16510938 DOI: 10.1088/1741-2560/3/1/002  1
2006 Chiu AW, Kang EE, Derchansky M, Carlen PL, Bardakjian BL. Online prediction of onsets of seizure-like events in hippocampal neural networks using wavelet artificial neural networks. Annals of Biomedical Engineering. 34: 282-94. PMID 16450192 DOI: 10.1007/s10439-005-9029-9  1
2006 Abdelmalik PA, Avoli M, Carlen PL. Intractable epilepsies of the neocortex: basic mechanisms. Advances in Neurology. 97: 117-27. PMID 16383121  1
2006 Tonkikh A, Janus C, El-Beheiry H, Pennefather PS, Samoilova M, McDonald P, Ouanounou A, Carlen PL. Calcium chelation improves spatial learning and synaptic plasticity in aged rats. Experimental Neurology. 197: 291-300. PMID 16039651 DOI: 10.1016/j.expneurol.2005.06.014  1
2006 Saraga F, Zhang XL, Zhang L, Carlen PL, Skinner FK. Exploring gap junction location and density in electrically coupled hippocampal oriens interneurons Neurocomputing. 69: 1048-1052. DOI: 10.1016/j.neucom.2005.12.043  1
2005 Chiu AW, Daniel S, Khosravani H, Carlen PL, Bardakjian BL. Prediction of seizure onset in an in-vitro hippocampal slice model of epilepsy using Gaussian-based and wavelet-based artificial neural networks. Annals of Biomedical Engineering. 33: 798-810. PMID 16078619 DOI: 10.1007/s10439-005-2346-1  1
2005 Khosravani H, Pinnegar CR, Mitchell JR, Bardakjian BL, Federico P, Carlen PL. Increased high-frequency oscillations precede in vitro low-Mg seizures. Epilepsia. 46: 1188-97. PMID 16060927 DOI: 10.1111/j.1528-1167.2005.65604.x  1
2005 Wentlandt K, Carlen PL, Kushnir M, Naus CC, El-Beheiry H. General anesthetics attenuate gap junction coupling in P19 cell line. Journal of Neuroscience Research. 81: 746-52. PMID 15971264 DOI: 10.1002/jnr.20577  1
2005 Wong T, Zhang XL, Asl MN, Wu CP, Carlen PL, Zhang L. Postnatal development of intrinsic GABAergic rhythms in mouse hippocampus. Neuroscience. 134: 107-20. PMID 15961234 DOI: 10.1016/j.neuroscience.2005.04.019  0.76
2005 Abdelmalik PA, Burnham WM, Carlen PL. Increased seizure susceptibility of the hippocampus compared with the neocortex of the immature mouse brain in vitro. Epilepsia. 46: 356-66. PMID 15730532 DOI: 10.1111/j.0013-9580.2005.34204.x  1
2005 Chiu AWL, Derchansky M, Kang EE, Carlen PL, Bardakjiant BL. Prevention of spontaneous seizure-like events in both in-silico and in-vitro epilepsy models Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 7: 3597-3600.  1
2004 Wentlandt K, Kushnir M, Naus CC, Carlen PL. Ethanol inhibits gap-junctional coupling between P19 cells. Alcoholism, Clinical and Experimental Research. 28: 1284-90. PMID 15365297 DOI: 10.1097/01.ALC.0000139705.17646.BA  1
2004 Zhang XL, Zhang L, Carlen PL. Electrotonic coupling between stratum oriens interneurones in the intact in vitro mouse juvenile hippocampus. The Journal of Physiology. 558: 825-39. PMID 15194737 DOI: 10.1113/jphysiol.2004.065649  1
2003 Casaubon L, Pohlmann-Eden B, Khosravani H, Carlen PL, Wennberg R. Video-EEG evidence of lateralized clinical features in primary generalized epilepsy with tonic-clonic seizures. Epileptic Disorders : International Epilepsy Journal With Videotape. 5: 149-56. PMID 14684350  1
2003 Sazgar M, Carlen PL, Wennberg R. Panic attack semiology in right temporal lobe epilepsy. Epileptic Disorders : International Epilepsy Journal With Videotape. 5: 93-100. PMID 12875952  1
2003 Samoilova M, Li J, Pelletier MR, Wentlandt K, Adamchik Y, Naus CC, Carlen PL. Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: increased gap junctional function and expression. Journal of Neurochemistry. 86: 687-99. PMID 12859682 DOI: 10.1046/j.1471-4159.2003.01893.x  1
2003 Fushiki S, Perez Velazquez JL, Zhang L, Bechberger JF, Carlen PL, Naus CC. Changes in neuronal migration in neocortex of connexin43 null mutant mice. Journal of Neuropathology and Experimental Neurology. 62: 304-14. PMID 12638734  1
2003 McAndrews MP, Weiss RT, Sandor P, Taylor A, Carlen PL, Shapiro CM. Cognitive effects of long-term benzodiazepine use in older adults Human Psychopharmacology. 18: 51-57. PMID 12532315 DOI: 10.1002/hup.453  1
2003 Khosravani H, Carlen PL, Velazquez JL. The control of seizure-like activity in the rat hippocampal slice. Biophysical Journal. 84: 687-95. PMID 12524321 DOI: 10.1016/S0006-3495(03)74888-7  1
2002 Frantseva M, Perez Velazquez JL, Tonkikh A, Adamchik Y, Carlen PL. Neurotrauma/neurodegeneration and mitochondrial dysfunction. Progress in Brain Research. 137: 171-6. PMID 12440367  0.6
2002 Jahromi SS, Wentlandt K, Piran S, Carlen PL. Anticonvulsant actions of gap junctional blockers in an in vitro seizure model. Journal of Neurophysiology. 88: 1893-902. PMID 12364515  1
2002 Carlen PL, Pelletier MR, Ouanounou A, Tymianski M, Zhang L. Neuroprotective strategies in epilepsy Advances in Experimental Medicine and Biology. 497: 209-224. PMID 11993734  1
2002 Li J, Pelletier MR, Perez Velazquez JL, Carlen PL. Reduced cortical synaptic plasticity and GluR1 expression associated with fragile X mental retardation protein deficiency. Molecular and Cellular Neurosciences. 19: 138-51. PMID 11860268 DOI: 10.1006/mcne.2001.1085  1
2002 Frantseva MV, Kokarovtseva L, Naus CG, Carlen PL, MacFabe D, Perez Velazquez JL. Specific gap junctions enhance the neuronal vulnerability to brain traumatic injury Journal of Neuroscience. 22: 644-653. PMID 11826094  1
2001 Frantseva MV, Carlen PL, Perez Velazquez JL. Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons Free Radical Biology and Medicine. 31: 1216-1227. PMID 11705700 DOI: 10.1016/S0891-5849(01)00705-5  1
2001 Li J, Shen H, Naus CCG, Zhang L, Carlen PL. Upregulation of gap junction connexin 32 with epileptiform activity in the isolated mouse hippocampus Neuroscience. 105: 589-598. PMID 11516826 DOI: 10.1016/S0306-4522(01)00204-4  1
2001 Perez Velazquez JL, Carlen PL, Skinner FK. Artificial electrotonic coupling affects neuronal firing patterns depending upon cellular characteristics. Neuroscience. 103: 841-9. PMID 11274798 DOI: 10.1016/S0306-4522(01)00019-7  1
2001 Valiante TA, Perez Velazquez JL, Carlen PL. Recording and analysis of putative direct electrical interactions in the mammalian brain Methods in Molecular Biology (Clifton, N.J.). 154: 395-405. PMID 11218661  1
2000 Edwards HE, Epps T, Carlen PL, MacLusky NJ. Progestin receptors mediate progesterone suppression of epileptiform activity in tetanized hippocampal slices in vitro Neuroscience. 101: 895-906. PMID 11113338 DOI: 10.1016/S0306-4522(00)00439-5  1
2000 Pelletier MR, Pahapill PA, Pennefather PS, Carlen PL. Analysis of single K(ATP) channels in mammalian dentate gyrus granule cells. Journal of Neurophysiology. 84: 2291-301. PMID 11067973  1
2000 Jahromi SS, Pelletier MR, McDonald PJ, Khosravani H, Carlen PL. Antiepileptic efficacy of topiramate: assessment in two in vitro seizure models. Brain Research. 872: 20-8. PMID 10924671 DOI: 10.1016/S0006-8993(00)02410-0  1
2000 Perez Velazquez JL, Frantseva MV, Huzar DV, Carlen PL. Mitochondrial porin required for ischemia-induced mitochondrial dysfunction and neuronal damage Neuroscience. 97: 363-369. PMID 10799768 DOI: 10.1016/S0306-4522(99)00569-2  1
2000 Zhang XL, Velumian AA, Jones OT, Carlen PL. Modulation of high-voltage-activated calcium channels in dentate granule cells by topiramate Epilepsia. 41. PMID 10768302  1
2000 Frantseva MV, Velazquez JLP, Hwang PA, Carlen PL. Free radical production correlates with cell death in an in vitro model of epilepsy European Journal of Neuroscience. 12: 1431-1439. PMID 10762371 DOI: 10.1046/j.1460-9568.2000.00016.x  1
2000 Perez Velazquez JL, Carlen PL. Gap junctions, synchrony and seizures Trends in Neurosciences. 23: 68-74. PMID 10652547 DOI: 10.1016/S0166-2236(99)01497-6  1
1999 Frantseva MV, Carlen PL, Perez Velazquez JL. Molecular mechanisms of free radical production and protective efficacies of antioxidants in in vitro ischemia-reperfusion Annals of the New York Academy of Sciences. 893: 286-289. PMID 10672250  1
1999 Perez Velazquez JL, Carlen PL. Synchronization of GABAergic interneuronal networks during seizure-like activity in the rat horizontal hippocampal slice European Journal of Neuroscience. 11: 4110-4118. PMID 10583499 DOI: 10.1046/j.1460-9568.1999.00837.x  1
1999 Frantseva MV, Carlen PL, El-Beheiry H. A submersion method to induce hypoxic damage in organotypic hippocampal cultures Journal of Neuroscience Methods. 89: 25-31. PMID 10476680 DOI: 10.1016/S0165-0270(99)00030-8  1
1999 Pelletier MR, Wadia JS, Mills LR, Carlen PL. Seizure-induce cell death produced by repeated tetanic stimulation in vitro: Possible role of endoplasmic reticulum calcium stores Journal of Neurophysiology. 81: 3054-3064. PMID 10368420  1
1999 Jahromi BS, Zhang L, Carlen PL, Pennefather P. Differential time-course of slow afterhyperpolarizations and associated Ca2+ transients in rat CA1 pyramidal neurons: further dissociation by Ca2+ buffer. Neuroscience. 88: 719-26. PMID 10363812 DOI: 10.1016/S0306-4522(98)00203-6  1
1999 Velumian AA, Carlen PL. Differential control of three after-hyperpolarizations in rat hippocampal neurones by intracellular calcium buffering Journal of Physiology. 517: 201-216. PMID 10226160 DOI: 10.1111/j.1469-7793.1999.0201z.x  1
1999 Skinner FK, Zhang L, Velazquez JL, Carlen PL. Bursting in inhibitory interneuronal networks: A role for gap-junctional coupling. Journal of Neurophysiology. 81: 1274-83. PMID 10085354  1
1999 Ouanounou A, Zhang L, Charlton MP, Carlen PL. Differential modulation of synaptic transmission by calcium chelators in young and aged hippocampal CA1 neurons: evidence for altered calcium homeostasis in aging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 906-15. PMID 9920654  1
1999 Skinner FK, Zhang L, Velazquez JLP, Carlen PL. Gap junctions are needed to stabilize slow bursting behaviour Neurocomputing. 26: 517-523. DOI: 10.1016/S0925-2312(99)00043-0  1
1998 Frantseva MV, Perez Velazquez JL, Carlen PL. Changes in membrane and synaptic properties of thalamocortical circuitry caused by hydrogen peroxide Journal of Neurophysiology. 80: 1317-1326. PMID 9744941  1
1998 Ouanounou A, Carlen PL, El-Beheiry H. Enhanced isoflurane suppression of excitatory synaptic transmission in the aged rat hippocampus British Journal of Pharmacology. 124: 1075-1082. PMID 9720776 DOI: 10.1038/sj.bjp.0701911  1
1997 Perez Velazquez JL, Han D, Carlen PL. Neurotransmitter modulation of gap junctional communication in the rat hippocampus European Journal of Neuroscience. 9: 2522-2531. PMID 9517457 DOI: 10.1111/j.1460-9568.1997.tb01681.x  1
1997 Watson PL, Weiner JL, Carlen PL. Effects of variations in hippocampal slice preparation protocol on the electrophysiological stability, epileptogenicity and graded hypoxia responses of CA1 neurons. Brain Research. 775: 134-43. PMID 9439837 DOI: 10.1016/S0006-8993(97)00893-7  1
1997 Zhang Y, Carlen PL, Zhang L. Kinetics of muscarinic reduction of I(sAHP) in hippocampal neurons: Effects of acetylcholinesterase inhibitors Journal of Neurophysiology. 78: 2999-3007. PMID 9405519  1
1997 Perez Velazquez JL, Frantseva MV, Carlen PL. In vitro ischemia promotes glutamate-mediated free radical generation and intracellular calcium accumulation in hippocampal pyramidal neurons Journal of Neuroscience. 17: 9085-9094. PMID 9364055  1
1997 Shinno K, Zhang L, Eubanks JH, Carlen PL, Wallace MC. Transient ischemia induces an early decrease of synaptic transmission in CA1 neurons of rat hippocampus: Electrophysiologic study in brain slices Journal of Cerebral Blood Flow and Metabolism. 17: 955-966. PMID 9307609  1
1997 Noldy NE, Carlen PL. Event-related potential changes in cocaine withdrawal: Evidence for long-term cognitive effects Neuropsychobiology. 36: 53-56. PMID 9211446  1
1997 Velumian AA, Zhang L, Pennefather P, Carlen PL. Reversible inhibition of IK, IAHP, Ih and ICa currents by internally applied gluconate in rat hippocampal pyramidal neurones. PflüGers Archiv : European Journal of Physiology. 433: 343-50. PMID 9064651 DOI: 10.1007/s004240050286  1
1997 Valiante TA, Abdul-Ghani MA, Carlen PL, Pennefather P. Analysis of current fluctuations during after-hyperpolarization current in dentate granule neurones of the rat hippocampus. The Journal of Physiology. 499: 121-34. PMID 9061644  1
1996 Pelletier MR, Carlen PL. Repeated tetanic stimulation in piriform cortex in vitro: Epileptogenesis and pharmacology Journal of Neurophysiology. 76: 4069-4079. PMID 8985901  1
1996 Spigelman I, Tymianski M, Wallace CM, Carlen PL, Velumian AA. Modulation of hippocampal synaptic transmission by low concentrations of cell-permeant Ca2+ chelators: effects of Ca2+ affinity, chelator structure and binding kinetics. Neuroscience. 75: 559-72. PMID 8931019 DOI: 10.1016/0306-4522(96)00283-7  1
1996 Zhang L, Han D, Carlen PL. Temporal specificity of muscarinic synaptic modulation of the Ca 2+-dependent K + current (I(sAHP)) in rat hippocampal neurones Journal of Physiology. 496: 395-405. PMID 8910224  1
1996 Abdul-Ghani MA, Valiante TA, Carlen PL, Pennefather PS. Tyrosine kinase inhibitors enhance a Ca(2+)-activated K+ current (IAHP) and reduce IAHP suppression by a metabotropic glutamate receptor agonist in rat dentate granule neurones. The Journal of Physiology. 496: 139-44. PMID 8910202  1
1996 Abdul-Ghani MA, Valiante TA, Carlen PL, Pennefather PS. Metabotropic glutamate receptors coupled to IP3 production mediate inhibition of IAHP in rat dentate granule neurons. Journal of Neurophysiology. 76: 2691-700. PMID 8899638  1
1996 Perez Velazquez JL, Carlen PL. Development of firing patterns and electrical properties in neurons of the rat ventrobasal thalamus Developmental Brain Research. 91: 164-170. PMID 8852366 DOI: 10.1016/0165-3806(95)00171-9  1
1996 El-Beheiry H, Ouanounou A, Carlen PL. Ageing potentiates anaesthetic-induced synaptic depression in hippocampal slices Neuroreport. 7: 502-504. PMID 8730815  1
1996 Ki-Rdiaiiy H, Otuanounou A, Carlen PL. Aging enhances isoflurane-1nduced suppression of excitatory synaptic transmission in hippocampal slices Faseb Journal. 10.  1
1996 Ouanounou A, Zhang L, Chariten MP, Carlen PL. Excitatory synaptic transmission is enhanced in aged hippocampal ca1 neurons by calcium chelators Faseb Journal. 10.  1
1995 Velumian AA, Thirlwell CJ, Carlen PL. Adapters for combined intrapipette pressure pulses and patch pipette step movements during 'blind' cell search in brain slices Journal of Neuroscience Methods. 62: 129-134. PMID 8750094 DOI: 10.1016/0165-0270(95)00067-4  1
1995 Valiante TA, Velazquez JLP, Jahromi SS, Carlen PL. Coupling potentials in CA1 neurons during calcium-free-induced field burst activity Journal of Neuroscience. 15: 6946-6956. PMID 7472451  1
1994 Weiner JL, Zhang L, Carlen PL. Potentiation of GABAA-mediated synaptic current by ethanol in hippocampal CA1 neurons: possible role of protein kinase C. The Journal of Pharmacology and Experimental Therapeutics. 268: 1388-95. PMID 8138953  1
1994 Perez-Velazquez JL, Valiante TA, Carlen PL. Modulation of gap junctional mechanisms during calcium-free induced field burst activity: A possible role for electrotonic coupling in epileptogenesis Journal of Neuroscience. 14: 4308-4317. PMID 8027781  1
1994 Menzano E, Carlen PL. Zinc deficiency and corticosteroids in the pathogenesis of alcoholic brain dysfunction - A review Alcoholism: Clinical and Experimental Research. 18: 895-901. PMID 7978102 DOI: 10.1111/j.1530-0277.1994.tb00057.x  1
1994 Perez-Velazquez JL, Valiante TA, Carlen PL. Changes in calcium currents during ethanol withdrawal in a genetic mouse model Brain Research. 649: 305-309. PMID 7953646 DOI: 10.1016/0006-8993(94)91077-4  1
1994 Tymianski M, Spigelman I, Zhang L, Carlen PL, Tator CH, Charlton MP, Wallace MC. Mechanism of action and persistence of neuroprotection by cell-permeant Ca2+ chelators. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 14: 911-23. PMID 7929656 DOI: 10.1038/jcbfm.1994.122  1
1994 Weiner JL, Zhang L, Carlen PL. Guanosine phosphate analogs modulate ethanol potentiation of GABAA-mediated synaptic currents in hippocampal CA1 neurons. Brain Research. 665: 307-10. PMID 7895067 DOI: 10.1016/0006-8993(94)91352-8  1
1994 Noldy NE, Santos CV, Politzer N, Blair RDG, Carlen PL. Quantitative EEG changes in cocaine withdrawal: Evidence for long-term CNS effects Neuropsychobiology. 30: 189-196. PMID 7862268 DOI: 10.1159/000119160  1
1994 Tymianski M, Charlton MP, Carlen PL, Tator CH. Properties of neuroprotective cell-permeant Ca2+ chelators: effects on [Ca2+]i and glutamate neurotoxicity in vitro. Journal of Neurophysiology. 72: 1973-92. PMID 7823112  1
1994 Mills LR, Niesen CE, So AP, Carlen PL, Spigelman I, Jones OT. N-type Ca2+ channels are located on somata, dendrites, and a subpopulation of dendritic spines on live hippocampal pyramidal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 6815-24. PMID 7525892  1
1993 Zhang L, Weiner JL, Carlen PL. Potentiation of gamma-aminobutyric acid type A receptor-mediated synaptic currents by pentobarbital and diazepam in immature hippocampal CA1 neurons. The Journal of Pharmacology and Experimental Therapeutics. 266: 1227-35. PMID 8396629  1
1993 Zhang L, Valiante TA, Carlen PL. Contribution of the low-threshold T-type calcium current in generating the post-spike depolarizing afterpotential in dentate granule neurons of immature rats Journal of Neurophysiology. 70: 223-231. PMID 8395576  1
1993 Velumian AA, Zhang L, Carlen PL. A simple method for internal perfusion of mammalian central nervous system neurones in brain slices with multiple solution changes Journal of Neuroscience Methods. 48: 131-139. PMID 8377515 DOI: 10.1016/S0165-0270(05)80015-9  1
1993 Jahromi SS, Schertzer S, Carlen PL. Cocaine actions on rat prefrontal cortical and hippocampal dentate granule neurons in vitro Synapse. 14: 121-127. PMID 8332944 DOI: 10.1002/syn.890140204  1
1993 Tymianski M, Wallace MC, Spigelman I, Uno M, Carlen PL, Tator CH, Charlton MP. Cell-permeant Ca2+ chelators reduce early excitotoxic and ischemic neuronal injury in vitro and in vivo. Neuron. 11: 221-35. PMID 8102532 DOI: 10.1016/0896-6273(93)90180-Y  1
1993 Tymianski M, Charlton MP, Carlen PL, Tator CH. Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2085-104. PMID 8097530  1
1993 Tymianski M, Charlton MP, Carlen PL, Tator CH. Secondary Ca2+ overload indicates early neuronal injury which precedes staining with viability indicators. Brain Research. 607: 319-23. PMID 7683241 DOI: 10.1016/0006-8993(93)91523-U  1
1992 Spigelman I, Zhang L, Carlen PL. Patch-clamp study of postnatal development of CA1 neurons in rat hippocampal slices: membrane excitability and K+ currents. Journal of Neurophysiology. 68: 55-69. PMID 1517828  1
1992 Fu P, Bardakjian BL, Carlen PL. Ethanol uncouples dentate granule neurons by increasing junctional resistance: A multineuronal system model approach Neuroscience. 51: 47-54. PMID 1465185 DOI: 10.1016/0306-4522(92)90469-I  1
1992 Zhang L, Weiner JL, Carlen PL. Muscarinic potentiation of IK in hippocampal neurons: electrophysiological characterization of the signal transduction pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4510-20. PMID 1432107  1
1992 Billia F, Baskys A, Carlen PL, De Boni U. Rearrangement of centromeric satellite DNA in hippocampal neurons exhibiting long-term potentiation. Brain Research. Molecular Brain Research. 14: 101-8. PMID 1323006 DOI: 10.1016/0169-328X(92)90016-5  1
1991 Baskys A, Carlen PL, Wojtowicz JM. Long-term potentiation of synaptic responses in the rat dentate gyrus is due to increased quantal content Neuroscience Letters. 127: 169-172. PMID 1881627 DOI: 10.1016/0304-3940(91)90786-S  1
1991 Zhang L, Spigelman I, Carlen PL. Development of GABA-mediated, chloride-dependent inhibition in CA1 pyramidal neurones of immature rat hippocampal slices. The Journal of Physiology. 444: 25-49. PMID 1822551  1
1991 Jahromi SS, Niesen C, Carlen PL. Amphetamine actions on pre- and postpubertal rat hippocampal dentate granule neurons Brain Research. 556: 33-43. PMID 1657305 DOI: 10.1016/0006-8993(91)90544-6  1
1991 Niesen C, Charlton MP, Carlen PL. Postsynaptic and presynaptic effects of the calcium chelator BAPTA on synaptic transmission in rat hippocampal dentate granule neurons. Brain Research. 555: 319-25. PMID 1657301 DOI: 10.1016/0006-8993(91)90358-3  1
1991 Carlen PL, Zhang L, Cullen N. Cellular electrophysiological actions of ethanol on mammalian neurons in brain slices Annals of the New York Academy of Sciences. 625: 17-25. PMID 1647722  1
1990 Gurevich N, Wu PH, Carlen PL. Serotonin agonist and antagonist actions in hippocampal CA1 neurons Canadian Journal of Physiology and Pharmacology. 68: 586-595. PMID 2340447  1
1990 McCrea DA, Shefchyk SJ, Carlen PL. Large reductions in composite monosynaptic EPSP amplitude following conditioning stimulation are not accounted for by increased postsynaptic conductances in motoneurons. Neuroscience Letters. 109: 117-22. PMID 2314627 DOI: 10.1016/0304-3940(90)90548-N  1
1990 Reynolds JN, Wu PH, Khanna JM, Carlen PL. Ethanol tolerance in hippocampal neurons: Adaptive changes in cellular responses to ethanol measured in vitro Journal of Pharmacology and Experimental Therapeutics. 252: 265-271. PMID 2299594  1
1990 Shandling M, Carlen PL, Lang AE. Parkinsonism in alcohol withdrawal: A follow-up study Movement Disorders. 5: 36-39. PMID 2296256  1
1990 Noldy NE, Carlen PL. Acute, withdrawal, and chronic alcohol effects in man: Event-related potential and quantitative EEG techniques Annals of Medicine. 22: 333-339. PMID 2291841 DOI: 10.3109/07853899009147916  1
1990 Noldy NE, Neiman J, El-Nesr B, Carlen PL. Late auditory evoked potentials: A method for monitoring drug effects on the central nervous system Neuropsychobiology. 23: 48-52. PMID 2280830 DOI: 10.1159/000118715  1
1990 Zhang L, Spigelman I, Carlen PL. Whole-cell patch study of GABAergic inhibition in CA1 neurons of immature rat hippocampal slices. Brain Research. Developmental Brain Research. 56: 127-30. PMID 2279324 DOI: 10.1016/0165-3806(90)90171-T  1
1990 Baskys A, Reynolds JN, Carlen PL. NMDA depolarizations and long-term potentiation are reduced in the aged rat neocortex Brain Research. 530: 142-146. PMID 2271944 DOI: 10.1016/0006-8993(90)90671-W  1
1990 Baskys A, Bernstein NK, Barolet AW, Carlen PL. NMDA and quisqualate reduce a Ca-dependent K+ current by a protein kinase-mediated mechanism. Neuroscience Letters. 112: 76-81. PMID 2200979 DOI: 10.1016/0304-3940(90)90325-4  1
1990 Neiman J, Lang AE, Fomazzari L, Carlen PL. Movement disorders in alcoholism: A review Neurology. 40: 741-746. PMID 2098000  1
1990 Kujtan PW, Carlen PL. Phencyclidine actions measured intracellularly in hippocampal CA1 neurons Canadian Journal of Physiology and Pharmacology. 68: 1351-1356. PMID 2078827  1
1990 Abarbanel JM, Carlen PL. Neurological effects of alcoholism Current Opinion in Neurology and Neurosurgery. 3: 403-407.  1
1989 Fu P, Bardakjian BL, D'Aguanno A, Carlen PL. Computation of the Passive Electrical Parameters of Neurons Using a System Model Ieee Transactions On Biomedical Engineering. 36: 55-64. PMID 2921062 DOI: 10.1109/10.16449  1
1989 D'Aguanno A, Bardakjian BL, Carlen PL. A system model for investigating passive electrical properties of neurons Biophysical Journal. 55: 1169-1182. PMID 2765654  1
1989 Reynolds JN, Carlen PL. The effects of midazolam on hippocampal dentate gyrus granule neurons from young and old Fischer 344 rats Canadian Journal of Physiology and Pharmacology. 67: 359-362. PMID 2758376  1
1989 Blaxter TJ, Carlen PL, Niesen C. Pharmacological and anatomical separation of calcium currents in rat dentate granule neurones in vitro Journal of Physiology. 412: 93-112. PMID 2557433  1
1989 Reynolds JN, Carlen PL. Diminished calcium currents in aged hippocampal dentate gyrus granule neurones Brain Research. 479: 384-390. PMID 2493966 DOI: 10.1016/0006-8993(89)91646-6  1
1989 Baskys A, C.E. N, Davies MF, Carlen PL. Modulatory actions of serotonin on ionic conductances of hippocampal dentate granule cells Neuroscience. 29: 443-451. PMID 2471114 DOI: 10.1016/0306-4522(89)90071-7  1
1989 Durand D, Saint-Cyr JA, Gurevich N, Carlen PL. Ethanol-induced dendritic alterations in hippocampal granule cells Brain Research. 477: 373-377. PMID 2467727 DOI: 10.1016/0006-8993(89)91430-3  1
1989 Neiman J, Carlen PL. Abused drugs and central nervous system dysfunction Current Opinion in Neurology and Neurosurgery. 2: 354-358.  1
1988 Blaxter TJ, Carlen PL. GABA responses in rat dentate granule neurons are mediated by chloride Canadian Journal of Physiology and Pharmacology. 66: 637-642. PMID 3416234  1
1988 Blaxter TJ, Carlen PL. Measurements of dendritic conductance changes to GABA in granule cells of the rat dentate gyrus Neuroscience. 24: 821-827. PMID 3380302 DOI: 10.1016/0306-4522(88)90070-X  1
1988 Niesen CE, Baskys A, Carlen PL. Reversed ethanol effects on potassium conductances in aged hippocampal dentate granule neurons Brain Research. 445: 137-141. PMID 3365551 DOI: 10.1016/0006-8993(88)91082-7  1
1988 Stewart PA, Hayakawa EM, Carlen PL. Ethanol and pentobarbital in combination increase blood-brain barrier permeability to horseradish peroxidase Brain Research. 443: 12-20. PMID 3359263 DOI: 10.1016/0006-8993(88)91593-4  1
1988 Carlen PL. A fascinating area of research. Commenting on a previous editorial by Clive G. Harper British Journal of Addiction. 83: 1243-1246. PMID 3233401  1
1988 Davies MF, Sasaki SE, Carlen PL. Hyperexcitability of hippocampal CA1 neurons in brain slices of rats chronically administered clonazepam Journal of Pharmacology and Experimental Therapeutics. 247: 737-744. PMID 3183966  1
1988 Reynolds JN, Baskys A, Carlen PL. The effects of serotonin on N-methyl-d-aspartate and synaptically evoked depolarizations in rat neocortical neurons Brain Research. 456: 286-292. PMID 3061564 DOI: 10.1016/0006-8993(88)90230-2  1
1988 Wu PH, Gurevich N, Carlen PL. Serotonin-1A receptor activation in hippocampal CA1 neurons by 8-hydroxy-2-(di-n-propylamino)tetralin, 5-methoxytryptamine and 5-hydroxytryptamine Neuroscience Letters. 86: 72-76. PMID 2966313 DOI: 10.1016/0304-3940(88)90185-1  1
1988 Carlen PL, Wu PH. Calcium and sedative-hypnotic drug actions International Review of Neurobiology. 29: 161-189. PMID 2456997  1
1988 Carlen PL. Metabolic disorders and neurotoxicology Current Opinion in Neurology and Neurosurgery. 1: 371.  1
1988 Carlen PL. Alcoholic brain disease and the Wernicke-Korsakoff syndrome Current Opinion in Neurology and Neurosurgery. 1: 372-376.  1
1987 Fornazzari L, Riley D, Wu P, Carlen PL. Toluene abuse and neurologic impairment: To the editor Neurology. 37: 356. PMID 3808325  1
1987 Baskys A, Niesen CE, Carlen PL. Altered modulatory actions of serotonin on dentate granule cells of aged rats Brain Research. 419: 112-118. PMID 3676719 DOI: 10.1016/0006-8993(87)90574-9  1
1987 Kujtan PW, Carlen PL. Dose-dependent effects of phencyclidine on hippocampal CA1 neurons Canadian Journal of Physiology and Pharmacology. 65: 842-846. PMID 3621046  1
1987 O'Beirne M, Gurevich N, Carlen PL. Pentobarbital inhibits hippocampal neurons by increasing potassium conductance Canadian Journal of Physiology and Pharmacology. 65: 36-41. PMID 3567717  1
1987 Carlen PL, Wilkinson DA. Reversibility of alcohol-related brain damage: Clinical and experimental observations Acta Medica Scandinavica. 222: 19-26. PMID 3478966  1
1987 Davies MF, Sasaki SE, Carlen PL. Benzodiazepine-induced epileptiform activity in vitro Brain Research. 437: 239-244. PMID 3435838 DOI: 10.1016/0006-8993(87)91639-8  1
1987 Carlen PL, Wilkinson DA. Alcohol-induced brain damage: Confounding variables Alcohol and Alcoholism. 37-41. PMID 3426702  1
1987 Carlen PL. The electrophysiology of potassium channels Recent Developments in Alcoholism : An Official Publication of the American Medical Society On Alcoholism, the Research Society On Alcoholism, and the National Council On Alcoholism. 5: 347-356. PMID 2436260  1
1986 D’Aguanno A, Bardakjian BL, Carlen PL. Passive Neuronal Membrane Parameters: Comparison of Optimization and Peeling Methods Ieee Transactions On Biomedical Engineering. 1188-1196. PMID 3817853 DOI: 10.1109/TBME.1986.325699  1
1986 Track NS, Carlen PL. Motilin and human pancreatic polypeptide measured in CSF from alcoholic and non-alcoholic neurological patients Peptides. 7: 1193-1195. PMID 3562321 DOI: 10.1016/0196-9781(86)90150-6  1
1986 Fornazzari L, Carlen PL, Kapur BM. Intravenous Abuse of Propylhexedrine (Benzedrex®) and the Risk of Brainstem Dysfunction in Young Adults Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 13: 337-339. PMID 2877725 DOI: 10.1017/S0317167100036696  1
1986 Blaxter TJ, Carlen PL, Davies MF, Kujtan PW. gamma‐Aminobutyric acid hyperpolarizes rat hippocampal pyramidal cells through a calcium‐dependent potassium conductance The Journal of Physiology. 373: 181-194. PMID 2427695 DOI: 10.1113/jphysiol.1986.sp016041  1
1985 Blaxter TJ, Carlen PL. Pre- and postsynaptic effects of baclofen in the rat hippocampal slice Brain Research. 341: 195-199. PMID 2994814 DOI: 10.1016/0006-8993(85)91489-1  1
1985 Carlen PL, Gurevich N, Davies MF, Blaxter TJ, O'Beirne M. Enhanced neuronal K+ conductance: A possible common mechanism for sedative-hypnotic drug action Canadian Journal of Physiology and Pharmacology. 63: 831-837. PMID 2864130  1
1984 Durand D, Carlen PL. Impairment of long-term potentiation in rat hippocampus following chronic ethanol treatment Brain Research. 308: 325-332. PMID 6541071 DOI: 10.1016/0006-8993(84)91072-2  1
1984 McMullen PA, Saint-Cyr JA, Carlen PL. Morphological alterations in rat CA1 hippocampal pyramidal cell dendrites resulting from chronic ethanol consumption and withdrawal. The Journal of Comparative Neurology. 225: 111-8. PMID 6539344 DOI: 10.1002/cne.902250112  1
1984 Carlen PL, Wilkinson DA, Wortzman G, Holgate R. Partially Reversible Cerebral Atrophy and Functional Improvement in Recently Abstinent Alcoholics Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 11: 441-446. PMID 6518426 DOI: 10.1017/S0317167100045972  1
1984 Durand D, Carlen PL. Decreased neuronal inhibition in vitro after long-term administration of ethanol Science. 224: 1359-1361. PMID 6328654  1
1984 Puil E, Carlen PL. Attenuation of glutamate-action, excitatory postsynaptic potentials, and spikes by intracellular QX 222 in hippocampal neurons. Neuroscience. 11: 389-98. PMID 6144079 DOI: 10.1016/0306-4522(84)90031-9  1
1983 Carlen PL, Gurevich N, Polc P. The excitatory effects of the specific benzodiazepine antagonist Ro 14-7437, measured intracellularly in hippocampal CA1 cells Brain Research. 271: 115-119. PMID 6883110 DOI: 10.1016/0006-8993(83)91370-7  1
1983 Carlen PL, Wilkinson DA. Assessment of neurological dysfunction and recovery in alcoholics: CT scanning and other techniques Substance and Alcohol Actions/Misuse. 4: 191-197. PMID 6648760  1
1983 Fornazzari L, Wilkinson DA, Kapur BM, Carlen PL. Cerebellar, cortical and functional impairment in toluene abusers Acta Neurologica Scandinavica. 67: 319-329. PMID 6613519  1
1983 Carlen PL, Gurevich N, Polc P. Low-dose benzodiazepine neuronal inhibition: enhanced Ca2+-mediated K+-conductance Brain Research. 271: 358-364. PMID 6311332 DOI: 10.1016/0006-8993(83)90302-5  1
1983 Kujtan PW, Carlen PL, Kapur BM. Δ9-tetrahydrocannabinol and cannabinol: Dose-dependent effects on evoked potentials in the hippocampal slice Canadian Journal of Physiology and Pharmacology. 61: 420-426. PMID 6305469  1
1983 Durand D, Carlen PL, Gurevich N. Electrotonnic parameters of rat dentate granule cells measured using short current pulses and HRP staining Journal of Neurophysiology. 50: 1080-1097. PMID 6196465  1
1982 Fornazzari L, Carlen PL. Transient Choreiform Dyskinesias During Alcohol Withdrawal Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 9: 89-90. PMID 7104894 DOI: 10.1017/S0317167100043742  1
1982 Carlen PL, Gurevich N, Durand D. Ethanol in low doses augments calcium-mediated mechanisms measured intracellularly in hippocampal neurons Science. 215: 306-309. PMID 7053581  1
1982 Fornazzari L, Carlen PL, Wilkinson DA, Kapur B. Irreversible cortical and cerebellar impairment in toluene abusers Neurology. 32.  1
1981 Durand D, Corrigall WA, Kujtan P, Carlen PL. Effects of low concentrations of ethanol on CA1 hippocampal neurons in vitro Canadian Journal of Physiology and Pharmacology. 59: 979-984. PMID 7296399  1
1981 Jacob MS, Carlen PL, Marshman JA, Sellers EM. Phencyclidine ingestion: drug abuse and psychosis. The International Journal of the Addictions. 16: 749-58. PMID 7287252 DOI: 10.3109/10826088109038866  1
1981 Carlen PL, Lee MA, Jacob M, Livshits O. Parkinsonism provoked by alcoholism Annals of Neurology. 9: 84-86. PMID 7212672  1
1981 Carlen PL, Durand D. Modelling the postsynaptic location and magnitude of tonic conductance changes resulting from neurotransmitters or drugs Neuroscience. 6: 839-846. PMID 6113561 DOI: 10.1016/0306-4522(81)90166-4  1
1981 Fornazzari L, Carlen PL. Transient dyskinesias during alcohol withdrawal Alcoholism: Clinical and Experimental Research. 5.  1
1981 Wilkinson DA, Carlen PL. Reversibility of brain and CSF abnormalities in abstinent chronic alcoholics Neuroendocrinology Letters. 3: 95.  1
1981 Sanhueza P, Kapur B, Fornazzari L, Carlen PL. Cerebrospinal fluid (CSF) acidosis induced by ethanol in rats Alcoholism: Clinical and Experimental Research. 5.  1
1980 Wilkinson DA, Carlen PL. Relation of neuropsychological test performance in alcoholics to brain morphology measured by computed tomography Advances in Experimental Medicine and Biology. 126: 683-699. PMID 7405704  1
1980 Zilm DH, Huszar L, Carlen PL, Kaplan HL, Wilkinson DA. EEG correlates of the alcohol-induced organic brain syndrome in man Clinical Toxicology. 16: 345-358. PMID 7398222 DOI: 10.3109/15563658008989958  1
1980 Wilkinson DA, Carlen PL. Neuropsychological and neurological assessment of alcoholism. Discrimination between groups of alcoholics Journal of Studies On Alcohol. 41: 129-139. PMID 7366207  1
1980 Carlen PL, Werman R, Yaari Y. Post-synaptic conductance increase associated with presynaptic inhibition in cat lumbar motoneurones. The Journal of Physiology. 298: 539-56. PMID 7359439 DOI: 10.1113/jphysiol.1980.sp013100  1
1980 Wilkinson DA, Carlen PL. Relationship of neuropsychological test performance to brain morphology in amnesic and non-amnesic chronic alcoholics Acta Psychiatrica Scandinavica. 62: 89-101. PMID 6935927  1
1980 Carlen PL, Wilkinson DA. Alcoholic brain damage and reversible deficits Acta Psychiatrica Scandinavica. 62: 103-118. PMID 6935915  1
1980 Carlen PL, Corrigall WA. Ethanol tolerance measured electrophysiologically in hippocampal slices and not in neuromuscular junctions from chronically ethanol-fed rats Neuroscience Letters. 17: 95-100. PMID 6892053 DOI: 10.1016/0304-3940(80)90068-3  1
1980 Zilm DH, Carlen PL, Wilkinson DA, Kaplan HL. Piracetam not effective in alcohol organic brain syndrome Clinical Research. 28.  1
1978 Carlen PL, Wortzman G, Holgate RC, Wilkinson DA, Rankin JG. Reversible cerebral atrophy in recently abstinent chronic alcoholics measured by computed tomography scans Science. 200: 1076-1078. PMID 653357  1
1978 Carlen PL, Wall PD, Nadvorna H, Steinbach T. Phantom limbs and related phenomena in recent traumatic amputations. Neurology. 28: 211-7. PMID 564474  1
1978 Carlen PL, Staiman AL, Corrigall WA. Acetaldehyde affects mammalian neuromuscular transmission without observable postsynaptic effects Canadian Journal of Physiology and Pharmacology. 56: 1063-1066. PMID 217509  1
1977 Ashby P, Carlen PL, MacLeod S, Sinha P. Ethanol and spinal presynaptic inhibition in man. Annals of Neurology. 1: 478-80. PMID 617261 DOI: 10.1002/ana.410010513  1
1976 Carlen PL, Kosower EM, Werman R. Diamide acts intracellularly to enhance transmitter release: the differential permeation of diamide, DIP, DIP+1 and DIP+2 across the nerve terminal membrane. Brain Research. 117: 277-85. PMID 990916 DOI: 10.1016/0006-8993(76)90735-6  1
1976 Werman R, Carlen PL. Unusual behavior of the La EPSP in cat spinal motoneurons. Brain Research. 112: 395-401. PMID 953715 DOI: 10.1016/0006-8993(76)90294-8  1
1976 Carlen PL, Kosower EM, Werman R. The thiol-oxidizing agent diamide increases transmitter release by decreasing calcium requirements for neuromuscular transmission in the frog. Brain Research. 117: 257-76. PMID 186154 DOI: 10.1016/0006-8993(76)90734-4  1
1971 Werman R, Carlen PL, Kushnir M, Kosower EM. Effect of the thiol-oxidizing agent, diamide, on acetylcholine release at the frog endplate. Nature: New Biology. 233: 120-1. PMID 4328799  1
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