Kyle Orwig - Publications

Affiliations: 
Microbiology and Molecular Genetics University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Molecular Biology, Cell Biology, Biochemistry

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Harancher MR, Sukhwani M, Castro CA, Hsieh MH, Orwig KE. Generation of two isogenic sickle cell disease induced pluripotent stem cell lines from testicular fibroblasts. Stem Cell Research. 73: 103257. PMID 38000347 DOI: 10.1016/j.scr.2023.103257  0.439
2023 Rajachandran S, Zhang X, Cao Q, Caldeira-Brant AL, Zhang X, Song Y, Evans M, Bukulmez O, Grow EJ, Nagano M, Orwig KE, Chen H. Dissecting the spermatogonial stem cell niche using spatial transcriptomics. Cell Reports. 42: 112737. PMID 37393620 DOI: 10.1016/j.celrep.2023.112737  0.34
2023 Munyoki SK, Orwig KE. Perspectives: Methods for Evaluating Primate Spermatogonial Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 2656: 341-364. PMID 37249880 DOI: 10.1007/978-1-0716-3139-3_18  0.514
2022 Nie X, Munyoki SK, Sukhwani M, Schmid N, Missel A, Emery BR, Stukenborg JB, Mayerhofer A, Orwig KE, Aston KI, Hotaling JM, Cairns BR, Guo J. Single-cell analysis of human testis aging and correlation with elevated body mass index. Developmental Cell. 57: 1160-1176.e5. PMID 35504286 DOI: 10.1016/j.devcel.2022.04.004  0.307
2022 Tran KTD, Valli-Pulaski H, Colvin A, Orwig KE. Male Fertility Preservation and Restoration Strategies for Patients Undergoing Gonadotoxic Therapies. Biology of Reproduction. PMID 35403667 DOI: 10.1093/biolre/ioac072  0.326
2022 Tran KTD, Sheng Y, Doungkamchan C, Castro CA, Orwig KE. Induced pluripotent stem cell line from a mouse model of human azoospermia with a frameshift mutation Tex11_1260Ins(TT). Stem Cell Research. 60: 102728. PMID 35240466 DOI: 10.1016/j.scr.2022.102728  0.356
2021 Khampang S, Cho IK, Punyawai K, Gill B, Langmo JN, Nath S, Greeson KW, Symosko KM, Fowler KL, Tian S, Statz JP, Steves AN, Parnpai R, White MA, Hennebold JD, ... Orwig KE, et al. Blastocyst development after fertilization with in vitro spermatids derived from nonhuman primate embryonic stem cells. F&S Science. 2: 365-375. PMID 34970648 DOI: 10.1016/j.xfss.2021.09.001  0.518
2021 Shen YC, Shami AN, Moritz L, Larose H, Manske GL, Ma Q, Zheng X, Sukhwani M, Czerwinski M, Sultan C, Chen H, Gurczynski SJ, Spence JR, Orwig KE, Tallquist M, et al. TCF21 mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice. Nature Communications. 12: 3876. PMID 34162856 DOI: 10.1038/s41467-021-24130-8  0.421
2021 Shetty G, Mitchell JM, Lam TNA, Phan TT, Zhang J, Tailor RC, Peters KA, Penedo MC, Hanna CB, Clark AT, Orwig KE, Meistrich ML. Postpubertal Spermatogonial Stem Cell Transplantation Restores Functional Sperm Production in Rhesus Monkeys Irradiated Before and After Puberty. Andrology. PMID 33960147 DOI: 10.1111/andr.13033  0.406
2021 Parker N, Laychur A, Sukwani M, Orwig KE, Oatley JM, Zhang C, Rutaganira FU, Shokat K, Wright WW. Spermatogonial Stem Cell Numbers Are Reduced by Transient Inhibition of GDNF Signaling but Restored by Self-Renewing Replication when Signaling Resumes. Stem Cell Reports. PMID 33636117 DOI: 10.1016/j.stemcr.2021.01.015  0.362
2020 Yersal N, Köse S, Horzum U, Özkavukcu S, Orwig KE, Korkusuz P. Leptin promotes proliferation of neonatal mouse stem/progenitor spermatogonia. Journal of Assisted Reproduction and Genetics. PMID 32840762 DOI: 10.1007/s10815-020-01929-w  0.434
2020 Tan K, Song HW, Thompson M, Munyoki SK, Sukhwani M, Hsieh TC, Orwig KE, Wilkinson MF. Transcriptome profiling reveals signaling conditions dictating human spermatogonia fate in vitro. Proceedings of the National Academy of Sciences of the United States of America. PMID 32661178 DOI: 10.1073/Pnas.2000362117  0.327
2020 Goossens E, Jahnukainen K, Mitchell RT, van Pelt A, Pennings G, Rives N, Poels J, Wyns C, Lane S, Rodriguez-Wallberg KA, Rives A, Valli-Pulaski H, Steimer S, Kliesch S, Braye A, ... ... Orwig KE, et al. Fertility preservation in boys: recent developments and new insights . Human Reproduction Open. 2020: hoaa016. PMID 32529047 DOI: 10.1093/Hropen/Hoaa016  0.501
2020 Shami AN, Zheng X, Munyoki SK, Ma Q, Manske GL, Green CD, Sukhwani M, Orwig KE, Li JZ, Hammoud SS. Single-Cell RNA Sequencing of Human, Macaque, and Mouse Testes Uncovers Conserved and Divergent Features of Mammalian Spermatogenesis. Developmental Cell. PMID 32504559 DOI: 10.1016/J.Devcel.2020.05.010  0.396
2020 Shetty G, Mitchell JM, Meyer JM, Wu Z, Lam TNA, Phan TT, Zhang J, Hill L, Tailor RC, Peters KA, Penedo MC, Hanna C, Orwig KE, Meistrich ML. Restoration of Functional Sperm Production in Irradiated Pubertal Rhesus Monkeys by Spermatogonial Stem Cell Transplantation. Andrology. PMID 32351003 DOI: 10.1111/andr.12807  0.399
2020 David S, Orwig KE. Spermatogonial Stem Cell Culture in Oncofertility. The Urologic Clinics of North America. 47: 227-244. PMID 32272995 DOI: 10.1016/j.ucl.2020.01.001  0.409
2020 Pelzman DL, Orwig KE, Hwang K. Progress in translational reproductive science: testicular tissue transplantation and in vitro spermatogenesis. Fertility and Sterility. PMID 32111477 DOI: 10.1016/j.fertnstert.2020.01.038  0.352
2020 Tan K, Song H, Thompson M, Munyoki S, Sukhwani M, Hsieh T, Orwig K, Wilkinson* M. MP38-11 TRANSCRIPTOME ANALYSIS REVEALS CONDITIONS FOR CULTURING HUMAN SPERMATOGONIAL STEM-LIKE CELLS The Journal of Urology. 203: e573. DOI: 10.1097/Ju.0000000000000887.011  0.527
2019 Dobrinski I, Orwig K. Brinster Spermatogonial Stem Cell Transplantation 25 Anniversary Symposium. The International Journal of Developmental Biology. 63: 573-578. PMID 32149366 DOI: 10.1387/Ijdb.190362Id  0.489
2019 Morimoto H, Kanatsu-Shinohara M, Orwig KE, Shinohara T. Expression and functional analyses of EPHA2 in mouse spermatogonial stem cells. Biology of Reproduction. PMID 31403678 DOI: 10.1093/biolre/ioz156  0.362
2019 Sakib S, Uchida A, Valenzuela-Leon P, Yu Y, Valli-Pulaski H, Orwig K, Ungrin M, Dobrinski I. Formation of organotypic testicular organoids in microwell culture†. Biology of Reproduction. 100: 1648-1660. PMID 30927418 DOI: 10.1093/Biolre/Ioz053  0.476
2019 Munyoki S, Shami AN, Hammoud S, Orwig KE. Single-cell RNA sequencing reveals novel markers of stem/progenitor spermatogonia in higher primates Fertility and Sterility. 112: e373. DOI: 10.1016/j.fertnstert.2019.07.1068  0.37
2018 Sosa E, Chen D, Rojas EJ, Hennebold JD, Peters KA, Wu Z, Lam TN, Mitchell JM, Sukhwani M, Tailor RC, Meistrich ML, Orwig KE, Shetty G, Clark AT. Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. Nature Communications. 9: 5339. PMID 30559363 DOI: 10.1038/S41467-018-07740-7  0.502
2018 Shetty G, Wu Z, Lam TNA, Phan TT, Orwig KE, Meistrich ML. Effect of hormone modulations on donor-derived spermatogenesis or colonization after syngeneic and xenotransplantation in mice. Andrology. PMID 30471208 DOI: 10.1111/andr.12571  0.418
2018 Shetty G, Mitchell JM, Lam TNA, Wu Z, Zhang J, Hill L, Tailor RC, Peters KA, Penedo MC, Orwig KE, Meistrich ML. Donor spermatogenesis in de novo formed seminiferous tubules from transplanted testicular cells in rhesus monkey testis. Human Reproduction (Oxford, England). PMID 30358843 DOI: 10.1093/humrep/dey316  0.303
2018 Murdock MH, David S, Swinehart IT, Reing JE, Tran K, Gassei K, Orwig KE, Badylak SF. Human testis extracellular matrix enhances human spermatogonial stem cell survival in vitro. Tissue Engineering. Part A. PMID 30311859 DOI: 10.1089/Ten.Tea.2018.0147  0.372
2018 Fayomi AP, Orwig KE. Spermatogonial stem cells and spermatogenesis in mice, monkeys and men. Stem Cell Research. 29: 207-214. PMID 29730571 DOI: 10.1016/j.scr.2018.04.009  0.515
2018 Fang F, Angulo B, Xia N, Sukhwani M, Wang Z, Carey CC, Mazurie A, Cui J, Wilkinson R, Wiedenheft B, Irie N, Surani MA, Orwig KE, Reijo Pera RA. A PAX5-OCT4-PRDM1 developmental switch specifies human primordial germ cells. Nature Cell Biology. PMID 29713018 DOI: 10.1038/S41556-018-0094-3  0.493
2018 Garbuzov A, Pech MF, Hasegawa K, Sukhwani M, Zhang RJ, Orwig KE, Artandi SE. Purification of GFRα1+ and GFRα1- Spermatogonial Stem Cells Reveals a Niche-Dependent Mechanism for Fate Determination. Stem Cell Reports. PMID 29337115 DOI: 10.1016/J.Stemcr.2017.12.009  0.497
2018 Valli-Pulaski H, Sukhwani M, Peters K, Orwig K. Optimizing Cryopreservation of Human Testicular Tissues Reproductive Biomedicine Online. 37: e4. DOI: 10.1016/J.Rbmo.2018.06.008  0.435
2017 Sosa E, Kim R, Rojas EJ, Hosohama L, Hennebold JD, Orwig KE, Clark AT. An integration-free, virus-free rhesus macaque induced pluripotent stem cell line (riPSC90) from embryonic fibroblasts. Stem Cell Research. 21: 5-8. PMID 28677539 DOI: 10.1016/J.Scr.2017.03.011  0.413
2017 Clark AT, Gkountela S, Chen D, Liu W, Sosa E, Sukhwani M, Hennebold JD, Orwig KE. Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23. Stem Cell Reports. PMID 28579394 DOI: 10.1016/J.Stemcr.2017.05.002  0.48
2017 Singh D, Paduch DA, Schlegel PN, Orwig KE, Mielnik A, Bolyakov A, Wright WW. The production of glial cell line-derived neurotrophic factor by human sertoli cells is substantially reduced in sertoli cell-only testes. Human Reproduction (Oxford, England). 1-10. PMID 28369535 DOI: 10.1093/humrep/dex061  0.379
2017 Gassei K, Sheng Y, Fayomi A, Mital P, Sukhwani M, Lin CC, Peters KA, Althouse A, Valli H, Orwig KE. DDX4-EGFP transgenic rat model for the study of germline development and spermatogenesis†. Biology of Reproduction. PMID 28339678 DOI: 10.1095/Biolreprod.116.142828  0.737
2016 Sosa E, Kim R, Rojas EJ, Hosohama L, Hennebold JD, Orwig KE, Clark AT. An integration-free, virus-free rhesus macaque induced pluripotent stem cell line (riPSC89) from embryonic fibroblasts. Stem Cell Research. 17: 444-447. PMID 27879222 DOI: 10.1016/J.Scr.2016.09.015  0.406
2016 Panula S, Reda A, Stukenborg JB, Ramathal C, Sukhwani M, Albalushi H, Edsgärd D, Nakamura M, Söder O, Orwig KE, Yamanaka S, Reijo Pera RA, Hovatta O. Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells. Plos One. 11: e0165268. PMID 27768780 DOI: 10.1371/journal.pone.0165268  0.515
2016 Song HW, Bettegowda A, Lake BB, Zhao AH, Skarbrevik D, Babajanian E, Sukhwani M, Shum EY, Phan MH, Plank TD, Richardson ME, Ramaiah M, Sridhar V, de Rooij DG, Orwig KE, et al. The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment. Cell Reports. 17: 149-64. PMID 27681428 DOI: 10.1016/J.Celrep.2016.08.090  0.369
2015 Pech MF, Garbuzov A, Hasegawa K, Sukhwani M, Zhang RJ, Benayoun BA, Brockman SA, Lin S, Brunet A, Orwig KE, Artandi SE. High telomerase is a hallmark of undifferentiated spermatogonia and is required for maintenance of male germline stem cells. Genes & Development. PMID 26584619 DOI: 10.1101/Gad.271783.115  0.493
2015 Ramathal C, Angulo B, Sukhwani M, Cui J, Durruthy-Durruthy J, Fang F, Schanes P, Turek PJ, Orwig KE, Reijo Pera R. DDX3Y gene rescue of a Y chromosome AZFa deletion restores germ cell formation and transcriptional programs. Scientific Reports. 5: 15041. PMID 26456624 DOI: 10.1038/srep15041  0.358
2015 Pech M, Garbuzov A, Sukhwani M, Benayoun B, Lin S, Brunet A, Orwig K, Artandi SE. Abstract 980: Encoding immortality: Transcriptional control of telomerase in stem cells in vivo Cancer Research. 75: 980-980. DOI: 10.1158/1538-7445.Am2015-980  0.603
2015 Valli H, Gassei K, Orwig KE. Stem cell therapies for male infertility: Where are we now and where are we going? Biennial Review of Infertility. 4: 17-39. DOI: 10.1007/978-3-319-17849-3_3  0.771
2014 Dominguez AA, Chiang HR, Sukhwani M, Orwig KE, Reijo Pera RA. Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies. Scientific Reports. 4: 6432. PMID 25242416 DOI: 10.1038/srep06432  0.301
2014 Gassei K, Valli H, Orwig KE. Whole-mount immunohistochemistry to study spermatogonial stem cells and spermatogenic lineage development in mice, monkeys, and humans. Methods in Molecular Biology (Clifton, N.J.). 1210: 193-202. PMID 25173170 DOI: 10.1007/978-1-4939-1435-7_15  0.777
2014 Medrano JV, Martínez-Arroyo AM, Sukhwani M, Noguera I, Quiñonero A, Martínez-Jabaloyas JM, Pellicer A, Remohí J, Orwig KE, Simón C. Germ cell transplantation into mouse testes procedure. Fertility and Sterility. 102: e11-2. PMID 25150391 DOI: 10.1016/j.fertnstert.2014.07.669  0.341
2014 Valli H, Sukhwani M, Dovey SL, Peters KA, Donohue J, Castro CA, Chu T, Marshall GR, Orwig KE. Fluorescence- and magnetic-activated cell sorting strategies to isolate and enrich human spermatogonial stem cells. Fertility and Sterility. 102: 566-580.e7. PMID 24890267 DOI: 10.1016/J.Fertnstert.2014.04.036  0.772
2014 Ramathal C, Durruthy-Durruthy J, Sukhwani M, Arakaki JE, Turek PJ, Orwig KE, Reijo Pera RA. Fate of iPSCs derived from azoospermic and fertile men following xenotransplantation to murine seminiferous tubules. Cell Reports. 7: 1284-97. PMID 24794432 DOI: 10.1016/j.celrep.2014.03.067  0.474
2014 Durruthy Durruthy J, Ramathal C, Sukhwani M, Fang F, Cui J, Orwig KE, Reijo Pera RA. Fate of induced pluripotent stem cells following transplantation to murine seminiferous tubules. Human Molecular Genetics. 23: 3071-84. PMID 24449759 DOI: 10.1093/hmg/ddu012  0.543
2014 Valli H, Phillips BT, Shetty G, Byrne JA, Clark AT, Meistrich ML, Orwig KE. Germline stem cells: toward the regeneration of spermatogenesis. Fertility and Sterility. 101: 3-13. PMID 24314923 DOI: 10.1016/J.Fertnstert.2013.10.052  0.776
2014 Puri P, Phillips BT, Suzuki H, Orwig KE, Rajkovic A, Lapinski PE, King PD, Feng GS, Walker WH. The transition from stem cell to progenitor spermatogonia and male fertility requires the SHP2 protein tyrosine phosphatase. Stem Cells (Dayton, Ohio). 32: 741-53. PMID 24123360 DOI: 10.1002/Stem.1572  0.697
2014 Valli H, Sukhwani M, Peters K, Althouse A, Orwig K. Optimal methods for recovery of transplantable stem cells from frozen/thawed human testicular tissue Fertility and Sterility. 102: e104. DOI: 10.1016/J.Fertnstert.2014.07.355  0.751
2014 Valli H, Phillips BT, Orwig KE, Gassei K, Nagano MC. Spermatogonial Stem Cells and Spermatogenesis Knobil and Neill's Physiology of Reproduction: Two-Volume Set. 1: 595-635. DOI: 10.1016/B978-0-12-397175-3.00015-6  0.773
2013 Dovey SL, Valli H, Hermann BP, Sukhwani M, Donohue J, Castro CA, Chu T, Sanfilippo JS, Orwig KE. Eliminating malignant contamination from therapeutic human spermatogonial stem cells. The Journal of Clinical Investigation. 123: 1833-43. PMID 23549087 DOI: 10.1172/Jci65822  0.757
2013 Gassei K, Orwig KE. SALL4 expression in gonocytes and spermatogonial clones of postnatal mouse testes. Plos One. 8: e53976. PMID 23326552 DOI: 10.1371/journal.pone.0053976  0.386
2012 Hermann BP, Sukhwani M, Winkler F, Pascarella JN, Peters KA, Sheng Y, Valli H, Rodriguez M, Ezzelarab M, Dargo G, Peterson K, Masterson K, Ramsey C, Ward T, Lienesch M, ... ... Orwig KE, et al. Spermatogonial stem cell transplantation into rhesus testes regenerates spermatogenesis producing functional sperm. Cell Stem Cell. 11: 715-26. PMID 23122294 DOI: 10.1016/J.Stem.2012.07.017  0.71
2012 Easley CA, Phillips BT, McGuire MM, Barringer JM, Valli H, Hermann BP, Simerly CR, Rajkovic A, Miki T, Orwig KE, Schatten GP. Direct differentiation of human pluripotent stem cells into haploid spermatogenic cells. Cell Reports. 2: 440-6. PMID 22921399 DOI: 10.1016/J.Celrep.2012.07.015  0.807
2012 Suzuki H, Ahn HW, Chu T, Bowden W, Gassei K, Orwig K, Rajkovic A. SOHLH1 and SOHLH2 coordinate spermatogonial differentiation. Developmental Biology. 361: 301-12. PMID 22056784 DOI: 10.1016/J.Ydbio.2011.10.027  0.4
2012 Valli H, Dovey SL, Sukhwani M, Orwig KE. Characterization and Enrichment of Human Spermatogonial Stem Cells; THY-1 (CD90) Is Not a Suitable Marker for SSC Enrichment. Biology of Reproduction. 87: 589-589. DOI: 10.1093/Biolreprod/87.S1.589  0.74
2011 Clark AT, Phillips BT, Orwig KE. Fruitful progress to fertility: male fertility in the test tube. Nature Medicine. 17: 1564-5. PMID 22146462 DOI: 10.1038/Nm.2594  0.558
2011 Hermann BP, Sukhwani M, Salati J, Sheng Y, Chu T, Orwig KE. Separating spermatogonia from cancer cells in contaminated prepubertal primate testis cell suspensions. Human Reproduction (Oxford, England). 26: 3222-31. PMID 22016413 DOI: 10.1093/humrep/der343  0.376
2011 Honaramooz A, Schlatt S, Orwig K, Kim NH. Recent advances in reproductive technologies. Veterinary Medicine International. 2011: 915031. PMID 21776358 DOI: 10.4061/2011/915031  0.365
2011 Hermann BP, Phillips BT, Orwig KE. The elusive spermatogonial stem cell marker? Biology of Reproduction. 85: 221-3. PMID 21565995 DOI: 10.1095/Biolreprod.111.093146  0.673
2011 Simerly C, McFarland D, Castro C, Lin CC, Redinger C, Jacoby E, Mich-Basso J, Orwig K, Mills P, Ahrens E, Navara C, Schatten G. Interspecies chimera between primate embryonic stem cells and mouse embryos: monkey ESCs engraft into mouse embryos, but not post-implantation fetuses. Stem Cell Research. 7: 28-40. PMID 21543277 DOI: 10.1016/J.Scr.2011.03.002  0.516
2010 Ben-Yehudah A, Easley CA, Hermann BP, Castro C, Simerly C, Orwig KE, Mitalipov S, Schatten G. Systems biology discoveries using non-human primate pluripotent stem and germ cells: novel gene and genomic imprinting interactions as well as unique expression patterns. Stem Cell Research & Therapy. 1: 24. PMID 20699013 DOI: 10.1186/Scrt24  0.523
2010 Phillips BT, Gassei K, Orwig KE. Spermatogonial stem cell regulation and spermatogenesis. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 365: 1663-78. PMID 20403877 DOI: 10.1098/Rstb.2010.0026  0.72
2010 Hermann BP, Sukhwani M, Hansel MC, Orwig KE. Spermatogonial stem cells in higher primates: are there differences from those in rodents? Reproduction (Cambridge, England). 139: 479-93. PMID 19880674 DOI: 10.1530/Rep-09-0255  0.527
2010 Valli H, Dovey SL, Hansel MC, Orwig KE. Immunophenotyping of Undifferentiated Spermatogonia in Human Testes. Biology of Reproduction. 83: 535-535. DOI: 10.1093/Biolreprod/83.S1.535  0.667
2010 Phillips BT, Orwig KE. Regulation of the RNA Binding Protein YBX1 in Mouse Undifferentiated Spermatogonia. Biology of Reproduction. 83: 407-407. DOI: 10.1093/Biolreprod/83.S1.407  0.522
2010 Dovey S, Valli H, Hermann B, Orwig K. Fluorescence-activated cell sorting may allow separation of malignant leukemic cells from a testicular cell suspension Fertility and Sterility. 94: S12. DOI: 10.1016/J.Fertnstert.2010.07.045  0.729
2009 Hermann BP, Sukhwani M, Simorangkir DR, Chu T, Plant TM, Orwig KE. Molecular dissection of the male germ cell lineage identifies putative spermatogonial stem cells in rhesus macaques. Human Reproduction (Oxford, England). 24: 1704-16. PMID 19336441 DOI: 10.1093/Humrep/Dep073  0.544
2008 Orwig KE, Ryu BY, Master SR, Phillips BT, Mack M, Avarbock MR, Chodosh L, Brinster RL. Genes involved in post-transcriptional regulation are overrepresented in stem/progenitor spermatogonia of cryptorchid mouse testes. Stem Cells (Dayton, Ohio). 26: 927-38. PMID 18203673 DOI: 10.1634/Stemcells.2007-0893  0.718
2008 Chebira A, Ozolek JA, Castro CA, Jenkinson WG, Gore M, Bhagavatula R, Khaimovich I, Ormon SE, Navara CS, Sukhwani M, Orwig KE, Ben-Yehudah A, Schatten G, Rohde GK, Kovačević J. Multiresolution identification of germ layer components in teratomas derived from human and nonhuman primate embryonic stem cells 2008 5th Ieee International Symposium On Biomedical Imaging: From Nano to Macro, Proceedings, Isbi. 979-982. DOI: 10.1109/ISBI.2008.4541162  0.421
2008 Orwig KE, Hermann BP, Simorangkir D, Plant TM, Sukhwani M. Recent Progress Studying Spermatogonial Stem Cells in Primates. Biology of Reproduction. 78: 89-90. DOI: 10.1093/Biolreprod/78.S1.89D  0.505
2007 Navara CS, Mich-Basso JD, Redinger CJ, Ben-Yehudah A, Jacoby E, Kovkarova-Naumovski E, Sukhwani M, Orwig K, Kaminski N, Castro CA, Simerly CR, Schatten G. Pedigreed primate embryonic stem cells express homogeneous familial gene profiles. Stem Cells (Dayton, Ohio). 25: 2695-704. PMID 17641389 DOI: 10.1634/Stemcells.2007-0286  0.46
2007 Hermann BP, Sukhwani M, Lin CC, Sheng Y, Tomko J, Rodriguez M, Shuttleworth JJ, McFarland D, Hobbs RM, Pandolfi PP, Schatten GP, Orwig KE. Characterization, cryopreservation, and ablation of spermatogonial stem cells in adult rhesus macaques. Stem Cells (Dayton, Ohio). 25: 2330-8. PMID 17585169 DOI: 10.1634/Stemcells.2007-0143  0.538
2007 Ryu BY, Orwig KE, Oatley JM, Lin CC, Chang LJ, Avarbock MR, Brinster RL. Efficient generation of transgenic rats through the male germline using lentiviral transduction and transplantation of spermatogonial stem cells. Journal of Andrology. 28: 353-60. PMID 17108363 DOI: 10.2164/Jandrol.106.001511  0.313
2006 Ryu BY, Orwig KE, Oatley JM, Avarbock MR, Brinster RL. Effects of aging and niche microenvironment on spermatogonial stem cell self-renewal. Stem Cells (Dayton, Ohio). 24: 1505-11. PMID 16456131 DOI: 10.1634/Stemcells.2005-0580  0.469
2005 Buageaw A, Sukhwani M, Ben-Yehudah A, Ehmcke J, Rawe VY, Pholpramool C, Orwig KE, Schlatt S. GDNF family receptor alpha1 phenotype of spermatogonial stem cells in immature mouse testes. Biology of Reproduction. 73: 1011-6. PMID 16014811 DOI: 10.1095/Biolreprod.105.043810  0.511
2004 Ryu BY, Orwig KE, Kubota H, Avarbock MR, Brinster RL. Phenotypic and functional characteristics of spermatogonial stem cells in rats. Developmental Biology. 274: 158-70. PMID 15355795 DOI: 10.1016/j.ydbio.2004.07.004  0.43
2004 Costoya JA, Hobbs RM, Barna M, Cattoretti G, Manova K, Sukhwani M, Orwig KE, Wolgemuth DJ, Pandolfi PP. Essential role of Plzf in maintenance of spermatogonial stem cells. Nature Genetics. 36: 653-9. PMID 15156143 DOI: 10.1038/Ng1367  0.446
2003 Ryu BY, Orwig KE, Avarbock MR, Brinster RL. Stem cell and niche development in the postnatal rat testis. Developmental Biology. 263: 253-63. PMID 14597200  0.476
2003 Brinster CJ, Ryu BY, Avarbock MR, Karagenc L, Brinster RL, Orwig KE. Restoration of fertility by germ cell transplantation requires effective recipient preparation. Biology of Reproduction. 69: 412-20. PMID 12672656 DOI: 10.1095/biolreprod.103.016519  0.357
2003 Shinohara T, Orwig KE, Avarbock MR, Brinster RL. Restoration of spermatogenesis in infertile mice by Sertoli cell transplantation. Biology of Reproduction. 68: 1064-71. PMID 12604661  0.483
2002 Orwig KE, Avarbock MR, Brinster RL. Retrovirus-mediated modification of male germline stem cells in rats. Biology of Reproduction. 67: 874-9. PMID 12193397  0.446
2002 Orwig KE, Ryu BY, Avarbock MR, Brinster RL. Male germ-line stem cell potential is predicted by morphology of cells in neonatal rat testes. Proceedings of the National Academy of Sciences of the United States of America. 99: 11706-11. PMID 12185252 DOI: 10.1073/pnas.182412099  0.482
2002 Shinohara T, Orwig KE, Avarbock MR, Brinster RL. Germ line stem cell competition in postnatal mouse testes. Biology of Reproduction. 66: 1491-7. PMID 11967215  0.513
2002 Orwig KE, Shinohara T, Avarbock MR, Brinster RL. Functional analysis of stem cells in the adult rat testis. Biology of Reproduction. 66: 944-9. PMID 11906912  0.508
2001 Nagano M, Brinster CJ, Orwig KE, Ryu BY, Avarbock MR, Brinster RL. Transgenic mice produced by retroviral transduction of male germ-line stem cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 13090-5. PMID 11606778 DOI: 10.1073/pnas.231473498  0.491
2001 Shinohara T, Orwig KE, Avarbock MR, Brinster RL. Remodeling of the postnatal mouse testis is accompanied by dramatic changes in stem cell number and niche accessibility. Proceedings of the National Academy of Sciences of the United States of America. 98: 6186-91. PMID 11371640 DOI: 10.1073/pnas.111158198  0.512
2000 Shinohara T, Orwig KE, Avarbock MR, Brinster RL. Spermatogonial stem cell enrichment by multiparameter selection of mouse testis cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 8346-51. PMID 10900001 DOI: 10.1073/pnas.97.15.8346  0.506
1996 Soares MJ, Chapman BM, Rasmussen CA, Dai G, Kamei T, Orwig KE. Differentiation of trophoblast endocrine cells. Placenta. 17: 277-89. PMID 8829210 DOI: 10.1016/S0143-4004(96)90051-X  0.426
1996 Soares MJ, Chapman BM, Peters TJ, Orwig KE, Kamei T, Cohick CB, Dai G. Trophoblast cell differentiation: Acquisition of endocrine activities Placenta. 17: A2. DOI: 10.1016/S0143-4004(96)90070-3  0.365
Show low-probability matches.