| Year |
Citation |
Score |
| 2015 |
Bakan A, Kapralov AA, Bayir H, Hu F, Kagan VE, Bahar I. Inhibition of Peroxidase Activity of Cytochrome c: De Novo Compound Discovery and Validation. Molecular Pharmacology. 88: 421-7. PMID 26078313 DOI: 10.1124/Mol.115.097816 |
0.473 |
|
| 2015 |
George Rosenker KM, Paquette WD, Johnston PA, Sharlow ER, Vogt A, Bakan A, Lazo JS, Wipf P. Synthesis and biological evaluation of 3-aminoisoquinolin-1(2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B. Bioorganic & Medicinal Chemistry. 23: 2810-8. PMID 25703307 DOI: 10.1016/J.Bmc.2015.01.043 |
0.344 |
|
| 2014 |
Korotchenko VN, Saydmohammed M, Vollmer LL, Bakan A, Sheetz K, Debiec KT, Greene KA, Agliori CS, Bahar I, Day BW, Vogt A, Tsang M. In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem : a European Journal of Chemical Biology. 15: 1436-45. PMID 24909879 DOI: 10.1002/Cbic.201402000 |
0.543 |
|
| 2014 |
Bakan A, Dutta A, Mao W, Liu Y, Chennubhotla C, Lezon TR, Bahar I. Evol and ProDy for bridging protein sequence evolution and structural dynamics. Bioinformatics (Oxford, England). 30: 2681-3. PMID 24849577 DOI: 10.1093/Bioinformatics/Btu336 |
0.667 |
|
| 2014 |
Jiang J, Bakan A, Kapralov AA, Silva KI, Huang Z, Amoscato AA, Peterson J, Garapati VK, Saxena S, Bayir H, Atkinson J, Bahar I, Kagan VE. Designing inhibitors of cytochrome c/cardiolipin peroxidase complexes: mitochondria-targeted imidazole-substituted fatty acids. Free Radical Biology & Medicine. 71: 221-30. PMID 24631490 DOI: 10.1016/J.Freeradbiomed.2014.02.029 |
0.493 |
|
| 2014 |
Sharlow ER, Wipf P, McQueeney KE, Bakan A, Lazo JS. Investigational inhibitors of PTP4A3 phosphatase as antineoplastic agents. Expert Opinion On Investigational Drugs. 23: 661-73. PMID 24625356 DOI: 10.1517/13543784.2014.892579 |
0.369 |
|
| 2014 |
Vollmer L, Vernetti L, Bakan A, Korotchenko V, Bahar I, Day B, Tsang M, Vogt A. Abstract 745: A non-redox reactive allosteric inhibitor of MAPK phosphatases with selective toxicity to human cancer cells Cancer Research. 74: 745-745. DOI: 10.1158/1538-7445.Am2014-745 |
0.525 |
|
| 2013 |
Dutta A, Bakan A, Bahar I. Druggability of Ionotropic Glutamate Receptor N-Terminal Domains Biophysical Journal. 104: 226a. DOI: 10.1016/J.Bpj.2012.11.1274 |
0.667 |
|
| 2012 |
Kurkcuoglu Z, Bakan A, Kocaman D, Bahar I, Doruker P. Coupling between catalytic loop motions and enzyme global dynamics. Plos Computational Biology. 8: e1002705. PMID 23028297 DOI: 10.1371/Journal.Pcbi.1002705 |
0.69 |
|
| 2012 |
Bakan A, Nevins N, Lakdawala AS, Bahar I. Druggability Assessment of Allosteric Proteins by Dynamics Simulations in the Presence of Probe Molecules. Journal of Chemical Theory and Computation. 8: 2435-2447. PMID 22798729 DOI: 10.1016/J.Bpj.2012.11.3081 |
0.602 |
|
| 2011 |
Meireles L, Gur M, Bakan A, Bahar I. Pre-existing soft modes of motion uniquely defined by native contact topology facilitate ligand binding to proteins. Protein Science : a Publication of the Protein Society. 20: 1645-58. PMID 21826755 DOI: 10.1002/Pro.711 |
0.645 |
|
| 2011 |
Bakan A, Meireles LM, Bahar I. ProDy: protein dynamics inferred from theory and experiments. Bioinformatics (Oxford, England). 27: 1575-7. PMID 21471012 DOI: 10.1093/Bioinformatics/Btr168 |
0.699 |
|
| 2011 |
Mustata G, Li M, Zevola N, Bakan A, Zhang L, Epperly M, Greenberger JS, Yu J, Bahar I. Development of small-molecule PUMA inhibitors for mitigating radiation-induced cell death. Current Topics in Medicinal Chemistry. 11: 281-90. PMID 21320058 DOI: 10.2174/156802611794072641 |
0.518 |
|
| 2011 |
Bakan A, Bahar I. Computational generation inhibitor-bound conformers of p38 MAP kinase and comparison with experiments. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 181-92. PMID 21121046 |
0.554 |
|
| 2011 |
McLaughlin J, Rella J, Bakan A, Kong L, Zhu L, Frederick D, Yende S, Ferrell R, Bahar I, Shapiro S, Angus D, Kaynar A. Impact of pro-domain stability of matrix metalloproteinase-8 on the outcome of sepsis Critical Care. 15: P278. DOI: 10.1186/Cc9698 |
0.416 |
|
| 2011 |
Zomot E, Bakan A, Shrivastava IH, De Chancie J, Lezon TR, Bahar I. Sodium-coupled secondary transporters: Insights from structure-based computations Molecular Machines. 199-230. DOI: 10.1142/9789814343466_0011 |
0.427 |
|
| 2010 |
Bahar I, Lezon TR, Bakan A, Shrivastava IH. Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins. Chemical Reviews. 110: 1463-97. PMID 19785456 DOI: 10.1021/Cr900095E |
0.635 |
|
| 2009 |
Bakan A, Bahar I. The intrinsic dynamics of enzymes plays a dominant role in determining the structural changes induced upon inhibitor binding. Proceedings of the National Academy of Sciences of the United States of America. 106: 14349-54. PMID 19706521 DOI: 10.1073/Pnas.0904214106 |
0.68 |
|
| 2009 |
Molina G, Vogt A, Bakan A, Dai W, Queiroz de Oliveira P, Znosko W, Smithgall TE, Bahar I, Lazo JS, Day BW, Tsang M. Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages. Nature Chemical Biology. 5: 680-7. PMID 19578332 DOI: 10.1038/Nchembio.190 |
0.52 |
|
| 2008 |
Bakan A, Lazo JS, Wipf P, Brummond KM, Bahar I. Toward a molecular understanding of the interaction of dual specificity phosphatases with substrates: insights from structure-based modeling and high throughput screening. Current Medicinal Chemistry. 15: 2536-44. PMID 18855677 DOI: 10.2174/092986708785909003 |
0.605 |
|
| 2007 |
Lazo JS, Skoko JJ, Werner S, Mitasev B, Bakan A, Koizumi F, Yellow-Duke A, Bahar I, Brummond KM. Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library. The Journal of Pharmacology and Experimental Therapeutics. 322: 940-7. PMID 17538006 DOI: 10.1124/Jpet.107.122242 |
0.556 |
|
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