Robert M. Straubinger, PhD/MS - Publications

1971-1975 English, Anthropology University of Rochester, Rochester, NY 
 1975-1977 Natural Sciences Roswell Park Cancer Institute, Buffalo, NY, United States 
 1978-1984 Pharmacology University of California at San Francisco Medical Center 
 1985-1988 Cardiovascular Research Inst. University of California at San Francisco Medical Center 
 1989- Pharmaceutical Sciences State University of New York, Buffalo, Buffalo, NY, United States 
Pharmacology, Nanotechnology, Cell Bology, Pharmaceutical Sciences, Biophysics

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Niu J, Wang X, Qu J, Mager DE, Straubinger RM. Pharmacodynamic modeling of synergistic birinapant/paclitaxel interactions in pancreatic cancer cells. Bmc Cancer. 20: 1024. PMID 33097020 DOI: 10.1186/s12885-020-07398-9  1
2020 Greene MK, Chen T, Robinson E, Straubinger NL, Minx C, Chan DKW, Wang J, Burrows JF, Van Schaeybroeck S, Baker JR, Caddick S, Longley DB, Mager DE, Straubinger RM, Chudasama V, et al. Controlled coupling of an ultrapotent auristatin warhead to cetuximab yields a next-generation antibody-drug conjugate for EGFR-targeted therapy of KRAS mutant pancreatic cancer. British Journal of Cancer. PMID 32913288 DOI: 10.1038/s41416-020-01046-6  1
2020 Johnston MC, Nicoll JA, Redmond KM, Smyth P, Greene MK, Wj M, Dkw C, Crawford N, Stott KJ, Fox JP, Straubinger NL, Roche S, Clynes M, Straubinger RM, Longley DB, et al. DR5-targeted, chemotherapeutic drug-loaded nanoparticles induce apoptosis and tumor regression in pancreatic cancer in vivo models. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32504778 DOI: 10.1016/j.jconrel.2020.05.046  1
2020 Roche S, O'Neill F, Murphy J, Swan N, Meiller J, Conlon NT, Geoghegan J, Conlon K, McDermott R, Rahman R, Toomey S, Straubinger NL, Straubinger RM, O'Connor R, McVey G, et al. Establishment and Characterisation by Expression Microarray of Patient-Derived Xenograft Panel of Human Pancreatic Adenocarcinoma Patients. International Journal of Molecular Sciences. 21. PMID 32024004 DOI: 10.3390/ijms21030962  1
2019 McDaid WJ, Greene MK, Johnston MC, Pollheimer E, Smyth P, McLaughlin K, Van Schaeybroeck S, Straubinger RM, Longley DB, Scott CJ. Repurposing of Cetuximab in antibody-directed chemotherapy-loaded nanoparticles in EGFR therapy-resistant pancreatic tumours. Nanoscale. PMID 31626255 DOI: 10.1039/c9nr07257h  0.32
2019 Wang J, Chan DK, Sen A, Ma WW, Straubinger RM. Tumor priming by SMO inhibition enhances antibody delivery and efficacy in a pancreatic ductal adenocarcinoma model. Molecular Cancer Therapeutics. PMID 31363010 DOI: 10.1158/1535-7163.MCT-18-0354  0.72
2019 Niu J, Straubinger RM, Mager DE. Pharmacodynamic Drug-Drug Interactions. Clinical Pharmacology and Therapeutics. PMID 30912119 DOI: 10.1002/cpt.1434  1
2019 Luo D, Carter KA, Molins EAG, Straubinger NL, Geng J, Shao S, Jusko WJ, Straubinger RM, Lovell JF. Pharmacokinetics and pharmacodynamics of liposomal chemophototherapy with short drug-light intervals. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30684512 DOI: 10.1016/j.jconrel.2019.01.030  1
2018 Ma WW, Xie H, Fetterly G, Pitzonka L, Whitworth A, LeVea C, Wilton J, Mantione K, Schihl S, Dy GK, Boland P, Iyer R, Tan W, Brady W, Straubinger RM, et al. A Phase Ib Study of the FGFR/VEGFR Inhibitor Dovitinib With Gemcitabine and Capecitabine in Advanced Solid Tumor and Pancreatic Cancer Patients. American Journal of Clinical Oncology. PMID 30418178 DOI: 10.1097/COC.0000000000000492  0.72
2018 Coleman O, Henry M, O'Neill F, Roche S, Swan N, Boyle L, Murphy J, Meiller J, Conlon NT, Geoghegan J, Conlon KC, Lynch V, Straubinger NL, Straubinger RM, McVey G, et al. A Comparative Quantitative LC-MS/MS Profiling Analysis of Human Pancreatic Adenocarcinoma, Adjacent-Normal Tissue, and Patient-Derived Tumour Xenografts. Proteomes. 6. PMID 30404163 DOI: 10.3390/proteomes6040045  0.96
2018 Zhu X, Shen X, Qu J, Straubinger RM, Jusko WJ. Multi-Scale Network Model Supported by Proteomics for Analysis of Combined Gemcitabine and Birinapant Effects in Pancreatic Cancer Cells. Cpt: Pharmacometrics & Systems Pharmacology. PMID 30084546 DOI: 10.1002/psp4.12320  1
2018 Zhu X, Trueman S, Straubinger RM, Jusko WJ. Physiologically-based pharmacokinetic and pharmacodynamic models for gemcitabine and birinapant in pancreatic cancer xenografts. Journal of Pharmacokinetics and Pharmacodynamics. PMID 30069744 DOI: 10.1007/s10928-018-9603-z  1
2018 Diep JK, Covelli J, Sharma R, Ruszaj DM, Kaye KS, Li J, Straubinger RM, Rao GG. A Comparison of Composition and In Vitro Activity of Polymyxin B Products. International Journal of Antimicrobial Agents. PMID 29807163 DOI: 10.1016/j.ijantimicag.2018.05.014  1
2018 Camblin AJ, Pace EA, Adams S, Curley MD, Rimkunas V, Nie L, Tan G, Bloom T, Iadevaia S, Baum J, Minx C, Czibere A, Louis CU, Drummond DC, Nielsen UB, ... ... Straubinger RM, et al. Dual inhibition of IGF-1R and ErbB3 enhances the activity of gemcitabine and nab-paclitaxel in preclinical models of pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29549161 DOI: 10.1158/1078-0432.CCR-17-2262  0.48
2018 Vaidya T, Straubinger RM, Ait-Oudhia S. Development and Evaluation of Tri-Functional Immunoliposomes for the Treatment of HER2 Positive Breast Cancer. Pharmaceutical Research. 35: 95. PMID 29536232 DOI: 10.1007/s11095-018-2365-x  0.8
2018 Zhu X, Shen X, Qu J, Straubinger RM, Jusko WJ. Proteomic Analysis of Combined Gemcitabine and Birinapant in Pancreatic Cancer Cells. Frontiers in Pharmacology. 9: 84. PMID 29520231 DOI: 10.3389/fphar.2018.00084  1
2018 Wang X, Niu J, Li J, Shen X, Shen S, Straubinger RM, Qu J. Temporal Effects of Combined Birinapant and Paclitaxel on Pancreatic Cancer Cells Investigated via Large-scale, Ion-Current-Based Quantitative Proteomics (IonStar). Molecular & Cellular Proteomics : McP. PMID 29358341 DOI: 10.1074/mcp.RA117.000519  1
2017 Nguyen J, Hossain SS, Cooke JRN, Ellis JA, Deci MB, Emala CW, Bruce JN, Bigio IJ, Straubinger RM, Joshi S. Flow arrest intra-arterial delivery of small TAT-decorated and neutral micelles to gliomas. Journal of Neuro-Oncology. PMID 28421460 DOI: 10.1007/s11060-017-2429-5  0.52
2016 Tu C, Mojica W, Straubinger RM, Li J, Shen S, Qu M, Nie L, Roberts R, An B, Qu J. Quantitative proteomic profiling of paired cancerous and normal colon epithelial cells isolated freshly from colorectal cancer patients. Proteomics. Clinical Applications. PMID 27943637 DOI: 10.1002/prca.201600155  1
2016 Miao X, Koch G, Ait-Oudhia S, Straubinger RM, Jusko WJ. Pharmacodynamic Modeling of Cell Cycle Effects for Gemcitabine and Trabectedin Combinations in Pancreatic Cancer Cells. Frontiers in Pharmacology. 7: 421. PMID 27895579 DOI: 10.3389/fphar.2016.00421  1
2016 Joshi S, Cooke JR, Chan DK, Ellis JA, Hossain SS, Singh-Moon RP, Wang M, Bigio IJ, Bruce JN, Straubinger RM. Liposome size and charge optimization for intraarterial delivery to gliomas. Drug Delivery and Translational Research. PMID 27091339 DOI: 10.1007/s13346-016-0294-y  1
2016 Shen S, Jiang X, Li J, Straubinger RM, Suarez M, Tu C, Duan X, Thompson AC, Qu J. Large-Scale, Ion-Current-Based Proteomic Investigation of the Rat Striatal Proteome in a Model of Short- and Long-Term Cocaine Withdrawal. Journal of Proteome Research. PMID 27018876 DOI: 10.1021/acs.jproteome.6b00137  1
2016 Nguyen J, Cooke JR, Ellis JA, Deci M, Emala CW, Bruce JN, Bigio IJ, Straubinger RM, Joshi S. Cationizable lipid micelles as vehicles for intraarterial glioma treatment. Journal of Neuro-Oncology. PMID 26903015 DOI: 10.1007/s11060-016-2088-y  1
2015 Miao X, Koch G, Straubinger RM, Jusko WJ. Pharmacodynamic modeling of combined chemotherapeutic effects predicts synergistic activity of gemcitabine and trabectedin in pancreatic cancer cells. Cancer Chemotherapy and Pharmacology. PMID 26604207 DOI: 10.1007/s00280-015-2907-4  1
2015 Roy Chaudhuri T, Straubinger NL, Pitoniak RF, Hylander BL, Repasky EA, Ma WW, Straubinger RM. Tumor-priming Smoothened inhibitor enhances deposition and efficacy of cytotoxic nanoparticles in a pancreatic cancer model. Molecular Cancer Therapeutics. PMID 26516158 DOI: 10.1158/1535-7163.MCT-15-0602  1
2015 Zhu X, Straubinger RM, Jusko WJ. Mechanism-based mathematical modeling of combined gemcitabine and birinapant in pancreatic cancer cells. Journal of Pharmacokinetics and Pharmacodynamics. 42: 477-96. PMID 26252969 DOI: 10.1007/s10928-015-9429-x  1
2015 Joshi S, Singh-Moon RP, Ellis JA, Chaudhuri DB, Wang M, Reif R, Bruce JN, Bigio IJ, Straubinger RM. Cerebral hypoperfusion-assisted intra-arterial deposition of liposomes in normal and glioma-bearing rats. Neurosurgery. 76: 92-100. PMID 25525695 DOI: 10.1227/NEU.0000000000000552  1
2014 Joshi S, Singh-Moon R, Wang M, Chaudhuri DB, Ellis JA, Bruce JN, Bigio IJ, Straubinger RM. Cationic surface charge enhances early regional deposition of liposomes after intracarotid injection. Journal of Neuro-Oncology. 120: 489-97. PMID 25195130 DOI: 10.1007/s11060-014-1584-1  1
2014 Joshi S, Singh-Moon RP, Wang M, Chaudhuri DB, Holcomb M, Straubinger NL, Bruce JN, Bigio IJ, Straubinger RM. Transient cerebral hypoperfusion assisted intraarterial cationic liposome delivery to brain tissue. Journal of Neuro-Oncology. 118: 73-82. PMID 24664370 DOI: 10.1007/s11060-014-1421-6  1
2014 Ait-Oudhia S, Mager DE, Straubinger RM. Application of pharmacokinetic and pharmacodynamic analysis to the development of liposomal formulations for oncology. Pharmaceutics. 6: 137-74. PMID 24647104 DOI: 10.3390/pharmaceutics6010137  1
2014 Zhang H, Hylander BL, LeVea C, Repasky EA, Straubinger RM, Adjei AA, Ma WW. Enhanced FGFR signalling predisposes pancreatic cancer to the effect of a potent FGFR inhibitor in preclinical models. British Journal of Cancer. 110: 320-9. PMID 24327018 DOI: 10.1038/bjc.2013.754  1
2013 O'Connell K, Li J, Engler F, Hennessy K, O'Neill F, Straubinger RM, Qu J, O'Connor R. Determination of the Proteomic Response to Lapatinib Treatment using a comprehensive and reproducible ion-current-based proteomics strategy. Journal of Proteomics and Genomics Research. 1: 27-42. PMID 29046878 DOI: 10.14302/issn.2326-0793.jpgr-13-257  1
2013 Hamed SS, Straubinger RM, Jusko WJ. Pharmacodynamic modeling of cell cycle and apoptotic effects of gemcitabine on pancreatic adenocarcinoma cells. Cancer Chemotherapy and Pharmacology. 72: 553-63. PMID 23835677 DOI: 10.1007/s00280-013-2226-6  1
2013 Pawaskar DK, Straubinger RM, Fetterly GJ, Hylander BH, Repasky EA, Ma WW, Jusko WJ. Synergistic interactions between sorafenib and everolimus in pancreatic cancer xenografts in mice. Cancer Chemotherapy and Pharmacology. 71: 1231-40. PMID 23455452 DOI: 10.1007/s00280-013-2117-x  1
2013 Pawaskar DK, Straubinger RM, Fetterly GJ, Hylander BH, Repasky EA, Ma WW, Jusko WJ. Physiologically based pharmacokinetic models for everolimus and sorafenib in mice. Cancer Chemotherapy and Pharmacology. 71: 1219-29. PMID 23455451 DOI: 10.1007/s00280-013-2116-y  1
2013 Pawaskar DK, Straubinger RM, Fetterly GJ, Ma WW, Jusko WJ. Interactions of everolimus and sorafenib in whole blood lymphocyte proliferation. Pharmaceutical Research. 30: 707-13. PMID 23151723 DOI: 10.1007/s11095-012-0909-z  1
2013 Ait-Oudhia S, Straubinger RM, Mager DE. Systems pharmacological analysis of paclitaxel-mediated tumor priming that enhances nanocarrier deposition and efficacy. The Journal of Pharmacology and Experimental Therapeutics. 344: 103-12. PMID 23115220 DOI: 10.1124/jpet.112.199109  1
2013 Pawaskar DK, Straubinger RM, Fetterly GJ, Ma WW, Jusko WJ. Interactions of everolimus and sorafenib in pancreatic cancer cells. The Aaps Journal. 15: 78-84. PMID 23054975 DOI: 10.1208/s12248-012-9417-7  1
2012 Roy Chaudhuri T, Arnold RD, Yang J, Turowski SG, Qu Y, Spernyak JA, Mazurchuk R, Mager DE, Straubinger RM. Mechanisms of tumor vascular priming by a nanoparticulate doxorubicin formulation. Pharmaceutical Research. 29: 3312-24. PMID 22798260 DOI: 10.1007/s11095-012-0823-4  1
2012 Ait-Oudhia S, Straubinger RM, Mager DE. Meta-analysis of nanoparticulate paclitaxel delivery system pharmacokinetics and model prediction of associated neutropenia. Pharmaceutical Research. 29: 2833-44. PMID 22588463 DOI: 10.1007/s11095-012-0775-8  1
2012 Trummer BJ, Iyer V, Balu-Iyer SV, O'Connor R, Straubinger RM. Physicochemical properties of epidermal growth factor receptor inhibitors and development of a nanoliposomal formulation of gefitinib. Journal of Pharmaceutical Sciences. 101: 2763-76. PMID 22581704 DOI: 10.1002/jps.23180  1
2012 Harrold JM, Straubinger RM, Mager DE. Combinatorial chemotherapeutic efficacy in non-Hodgkin lymphoma can be predicted by a signaling model of CD20 pharmacodynamics. Cancer Research. 72: 1632-41. PMID 22350416 DOI: 10.1158/0008-5472.CAN-11-2432  1
2012 Gaitonde P, Peng A, Straubinger RM, Bankert RB, Balu-Iyer SV. Downregulation of CD40 signal and induction of TGF-β by phosphatidylinositol mediates reduction in immunogenicity against recombinant human Factor VIII. Journal of Pharmaceutical Sciences. 101: 48-55. PMID 21953409 DOI: 10.1002/jps.22746  1
2011 Gaitonde P, Peng A, Straubinger RM, Bankert RB, Balu-Iyer SV. Phosphatidylserine reduces immune response against human recombinant Factor VIII in Hemophilia A mice by regulation of dendritic cell function. Clinical Immunology (Orlando, Fla.). 138: 135-45. PMID 21094627 DOI: 10.1016/j.clim.2010.10.006  1
2010 Peng A, Straubinger RM, Balu-Iyer SV. Phosphatidylinositol containing lipidic particles reduces immunogenicity and catabolism of factor VIII in hemophilia a mice. The Aaps Journal. 12: 473-81. PMID 20517659 DOI: 10.1208/s12248-010-9207-z  1
2010 Cao J, Gonzalez-Covarrubias V, Covarrubias VM, Straubinger RM, Wang H, Duan X, Yu H, Qu J, Blanco JG. A rapid, reproducible, on-the-fly orthogonal array optimization method for targeted protein quantification by LC/MS and its application for accurate and sensitive quantification of carbonyl reductases in human liver. Analytical Chemistry. 82: 2680-9. PMID 20218584 DOI: 10.1021/ac902314m  1
2010 Yang J, Mager DE, Straubinger RM. Comparison of two pharmacodynamic transduction models for the analysis of tumor therapeutic responses in model systems. The Aaps Journal. 12: 1-10. PMID 19902363 DOI: 10.1208/s12248-009-9155-7  1
2010 Zhou R, Mazurchuk RV, Tamburlin JH, Harrold JM, Mager DE, Straubinger RM. Differential pharmacodynamic effects of paclitaxel formulations in an intracranial rat brain tumor model. The Journal of Pharmacology and Experimental Therapeutics. 332: 479-88. PMID 19861574 DOI: 10.1124/jpet.109.160044  1
2009 Duan X, Young R, Straubinger RM, Page B, Cao J, Wang H, Yu H, Canty JM, Qu J. A straightforward and highly efficient precipitation/on-pellet digestion procedure coupled with a long gradient nano-LC separation and Orbitrap mass spectrometry for label-free expression profiling of the swine heart mitochondrial proteome. Journal of Proteome Research. 8: 2838-50. PMID 19290621 DOI: 10.1021/pr900001t  1
2009 Wang H, Straubinger RM, Aletta JM, Cao J, Duan X, Yu H, Qu J. Accurate localization and relative quantification of arginine methylation using nanoflow liquid chromatography coupled to electron transfer dissociation and orbitrap mass spectrometry. Journal of the American Society For Mass Spectrometry. 20: 507-19. PMID 19110445 DOI: 10.1016/j.jasms.2008.11.008  1
2008 Gaspar JR, Qu J, Straubinger NL, Straubinger RM. Highly selective and sensitive assay for paclitaxel accumulation by tumor cells based on selective solid phase extraction and micro-flow liquid chromatography coupled to mass spectrometry. The Analyst. 133: 1742-8. PMID 19082078 DOI: 10.1039/b806856a  1
2008 Yu H, Straubinger RM, Cao J, Wang H, Qu J. Ultra-sensitive quantification of paclitaxel using selective solid-phase extraction in conjunction with reversed-phase capillary liquid chromatography/tandem mass spectrometry. Journal of Chromatography. A. 1210: 160-7. PMID 18834593 DOI: 10.1016/j.chroma.2008.09.052  1
2008 Ramani K, Purohit V, Miclea R, Gaitonde P, Straubinger RM, Balu-Iyer SV. Passive transfer of polyethylene glycol to liposomal-recombinant human FVIII enhances its efficacy in a murine model for hemophilia A. Journal of Pharmaceutical Sciences. 97: 3753-64. PMID 18300296 DOI: 10.1002/jps.21266  1
2008 Ramani K, Miclea RD, Purohit VS, Mager DE, Straubinger RM, Balu-Iyer SV. Phosphatidylserine containing liposomes reduce immunogenicity of recombinant human factor VIII (rFVIII) in a murine model of hemophilia A. Journal of Pharmaceutical Sciences. 97: 1386-98. PMID 17705286 DOI: 10.1002/jps.21102  1
2007 Straubinger RM, Krzyzanski W, Francoforte CM, Qu J. Applications of quantitative pharmacodynamic effect markers in drug target identification and therapy development. Anticancer Research. 27: 1237-46. PMID 17593615  1
2007 Drake EJ, Cao J, Qu J, Shah MB, Straubinger RM, Gulick AM. The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa. The Journal of Biological Chemistry. 282: 20425-34. PMID 17502378 DOI: 10.1074/jbc.M611833200  1
2007 Qu J, Qu Y, Straubinger RM. Ultra-sensitive quantification of corticosteroids in plasma samples using selective solid-phase extraction and reversed-phase capillary high-performance liquid chromatography/tandem mass spectrometry. Analytical Chemistry. 79: 3786-93. PMID 17411010 DOI: 10.1021/ac062184r  1
2006 Qu J, Jusko WJ, Straubinger RM. Utility of cleavable isotope-coded affinity-tagged reagents for quantification of low-copy proteins induced by methylprednisolone using liquid chromatography/tandem mass spectrometry. Analytical Chemistry. 78: 4543-52. PMID 16808464 DOI: 10.1021/ac0521697  1
2005 Arnold RD, Mager DE, Slack JE, Straubinger RM. Effect of repetitive administration of Doxorubicin-containing liposomes on plasma pharmacokinetics and drug biodistribution in a rat brain tumor model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 8856-65. PMID 16361575 DOI: 10.1158/1078-0432.CCR-05-1365  1
2005 Qu J, Straubinger RM. Improved sensitivity for quantification of proteins using triply charged cleavable isotope-coded affinity tag peptides. Rapid Communications in Mass Spectrometry : Rcm. 19: 2857-64. PMID 16155978 DOI: 10.1002/rcm.2138  1
2005 Straubinger RM, Balasubramanian SV. Preparation and characterization of taxane-containing liposomes. Methods in Enzymology. 391: 97-117. PMID 15721376 DOI: 10.1016/S0076-6879(05)91005-7  1
2004 Arnold RD, Slack JE, Straubinger RM. Quantification of Doxorubicin and metabolites in rat plasma and small volume tissue samples by liquid chromatography/electrospray tandem mass spectroscopy. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 808: 141-52. PMID 15261807 DOI: 10.1016/j.jchromb.2004.04.030  1
2004 Straubinger RM, Arnold RD, Zhou R, Mazurchuk R, Slack JE. Antivascular and antitumor activities of liposome-associated drugs. Anticancer Research. 24: 397-404. PMID 15152936  1
2003 Fetterly GJ, Straubinger RM. Pharmacokinetics of paclitaxel-containing liposomes in rats. Aaps Pharmsci. 5: E32. PMID 15198520 DOI: 10.1208/ps050432  1
2002 Almon RR, DuBois DC, Brandenburg EH, Shi W, Zhang S, Straubinger RM, Jusko WJ. Pharmacodynamics and pharmacogenomics of diverse receptor-mediated effects of methylprednisolone in rats using microarray analysis. Journal of Pharmacokinetics and Pharmacodynamics. 29: 103-29. PMID 12361239 DOI: 10.1023/A:1019762323576  1
2002 Lorenz SA, Bigwarfe PM, Balasubramanian SV, Fetterly GJ, Straubinger RM, Wood TD. Noncovalent dimerization of paclitaxel in solution: evidence from electrospray ionization mass spectrometry. Journal of Pharmaceutical Sciences. 91: 2057-66. PMID 12210052 DOI: 10.1002/jps.10194  1
2002 Zhou R, Mazurchuk R, Straubinger RM. Antivasculature effects of doxorubicin-containing liposomes in an intracranial rat brain tumor model. Cancer Research. 62: 2561-6. PMID 11980650  1
2002 Balasubramanian SV, Campbell RB, Straubinger RM. Propofol, a general anesthetic, promotes the formation of fluid phase domains in model membranes. Chemistry and Physics of Lipids. 114: 35-44. PMID 11841824 DOI: 10.1016/S0009-3084(01)00199-2  1
2001 Fetterly GJ, Tamburlin JM, Straubinger RM. Paclitaxel pharmacodynamics: application of a mechanism-based neutropenia model. Biopharmaceutics & Drug Disposition. 22: 251-61. PMID 11754041 DOI: 10.1002/bdd.283  1
2001 Campbell RB, Balasubramanian SV, Straubinger RM. Influence of cationic lipids on the stability and membrane properties of paclitaxel-containing liposomes. Journal of Pharmaceutical Sciences. 90: 1091-105. PMID 11536214 DOI: 10.1002/jps.1063  1
2001 Campbell RB, Balasubramanian SV, Straubinger RM. Phospholipid-cationic lipid interactions: influences on membrane and vesicle properties. Biochimica Et Biophysica Acta. 1512: 27-39. PMID 11334622 DOI: 10.1016/S0005-2736(01)00290-5  1
2000 Balasubramanian SV, Bruenn J, Straubinger RM. Liposomes as formulation excipients for protein pharmaceuticals: A model protein study Pharmaceutical Research. 17: 344-350. PMID 10801224 DOI: 10.1023/A:1007561308498  1
1999 Zhou R, Balasubramanian SV, Kahl SB, Straubinger RM. Biopharmaceutics of boronated radiosensitizers: Liposomal formulation of MnBOPP (manganese chelate of 2,4-(α,β-dihydroxyethyl) deuterioporphyrin IX) and comparative toxicity in mice Journal of Pharmaceutical Sciences. 88: 912-917. PMID 10479353 DOI: 10.1021/js980454i  1
1999 Mazurchuk R, Zhou R, Straubinger RM, Chau RI, Grossman Z. Functional magnetic resonance (fMR) imaging of a rat brain tumor model: Implications for evaluation of tumor microvasculature and therapeutic response Magnetic Resonance Imaging. 17: 537-548. PMID 10231180 DOI: 10.1016/S0730-725X(98)00208-2  1
1998 Edgerton M, Koshlukova SE, Lo TE, Chrzan BG, Straubinger RM, Raj PA. Candidacidal activity of salivary histatins. Identification of a histatin 5-binding protein on Candida albicans. The Journal of Biological Chemistry. 273: 20438-47. PMID 9685398 DOI: 10.1074/jbc.273.32.20438  1
1997 Oh YK, Straubinger RM. Cellular retention of liposome-delivered anionic compounds modulated by a probenecid-sensitive anion transporter Pharmaceutical Research. 14: 1203-1209. PMID 9327449 DOI: 10.1023/A:1012158924547  1
1997 Sharma US, Sharma A, Chau RI, Straubinger RM. Liposome-mediated therapy of intracranial brain tumors in a rat model Pharmaceutical Research. 14: 992-998. PMID 9279878 DOI: 10.1023/A:1012136925030  1
1997 Balasubramanian SV, Straubinger RM, Morris ME. Salicylic acid induces changes in the physical properties of model and native kidney membranes Journal of Pharmaceutical Sciences. 86: 199-204. PMID 9040095 DOI: 10.1021/js9602756  1
1997 Oh YK, Straubinger RM. Impact of Mycobacterium avium infection on macrophage-liposome interaction Journal of Liposome Research. 7: 101-114.  1
1996 Sharma A, Sharma US, Straubinger RM. Paclitaxel-liposomes for intracavitary therapy of intraperitoneal P388 leukemia Cancer Letters. 107: 265-272. PMID 8947523 DOI: 10.1016/0304-3835(96)04380-7  1
1996 Oh YK, Straubinger RM. Intracellular fate of Mycobacterium avium: Use of dual-label spectrofluorometry to investigate the influence of bacterial viability opsonization on phagosomal pH phagosome-lysosome interaction Infection and Immunity. 64: 319-325. PMID 8557358  1
1995 Sharma US, Balasubbamanian SV, Straubinger RM. Pharmaceutical and physical properties of paclitaxel (Taxol) complexes with cyclodextrins Journal of Pharmaceutical Sciences. 84: 1223-1230. PMID 8801338 DOI: 10.1002/jps.2600841015  1
1995 Sharma A, Straubinger RM, Ojima I, Bernacki RJ. Antitumor efficacy of taxane liposomes on a human ovarian tumor xenograft in nude athymic mice Journal of Pharmaceutical Sciences. 84: 1400-1404. PMID 8748320 DOI: 10.1002/jps.2600841204  1
1995 Oh YK, Nix DE, Straubinger RM. Formulation and efficacy of liposome-encapsulated antibiotics for therapy of intracellular Mycobacterium avium infection Antimicrobial Agents and Chemotherapy. 39: 2104-2111. PMID 8540724  1
1995 Lee MJ, Straubinger RM, Jusko WJ. Physicochemical, Pharmacokinetic and Pharmacodynamic Evaluation of Liposomal Tacrolimus (FK 506) in Rats Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 12: 1055-1059. PMID 7494802 DOI: 10.1023/A:1016222817860  1
1994 Sharma A, Straubinger RM. Novel Taxol Formulations: Preparation and Characterization of Taxol-Containing Liposomes Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 11: 889-896. PMID 7937531 DOI: 10.1023/A:1018994111594  1
1994 Sharma A, Conway WD, Straubinger RM. Reversed-phase high-performance liquid chromatographic determination of taxol in mouse plasma Journal of Chromatography B: Biomedical Sciences and Applications. 655: 315-319. PMID 7915939 DOI: 10.1016/0378-4347(94)00117-0  1
1994 Balasubramanian SV, Straubinger RM. Taxol-lipid interactions: Taxol-dependent effects on the physical properties of model membranes Biochemistry. 33: 8941-8947. PMID 7913831  1
1994 Balasubramanian SV, Alderfer JL, Straubinger RM. Solvent- and concentration-dependent molecular interactions of taxol (Paclitaxel) Journal of Pharmaceutical Sciences. 83: 1470-1476. PMID 7884672 DOI: 10.1002/jps.2600831021  1
1994 Chau R, Bisson MA, Siegel A, Elkin G, Klim P, Straubinger RM. Distribution of charasomes in Chara: Re-establishment and loss in darkness and correlation with banding and inorganic carbon uptake Australian Journal of Plant Physiology. 21: 113-123.  1
1993 Huang LR, Straubinger RM, Kahl SB, Koo MS, Alletto JJ, Mazurchuk R, Chau RI, Thamer SL, Fiel RJ. Boronated metalloporphyrins: a novel approach to the diagnosis and treatment of cancer using contrast-enhanced MR imaging and neutron capture therapy. Journal of Magnetic Resonance Imaging : Jmri. 3: 351-6. PMID 8448397 DOI: 10.1002/jmri.1880030210  1
1993 Straubinger RM. pH-Sensitive liposomes for delivery of macromolecules into cytoplasm of cultured cells Methods in Enzymology. 221: 361-376. PMID 8361384  1
1993 Sharma A, Straubinger NL, Straubinger RM. Modulation of Human Ovarian Tumor Cell Sensitivity to N-(Phosphonacetyl)-L-Aspartate (PALA) by Liposome Drug Carriers Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 10: 1434-1441. PMID 8272404 DOI: 10.1023/A:1018963006703  1
1993 Mishina EV, Straubinger RM, Pyszczynski NA, Jusko WJ. Enhancement of Tissue Delivery and Receptor Occupancy of Methylprednisolone in Rats by a Liposomal Formulation Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 10: 1402-1410. PMID 8272400 DOI: 10.1023/A:1018954704886  1
1993 Straubinger RM, Sharma A, Murray M, Mayhew E. Novel Taxol formulations: Taxol-containing liposomes Journal of the National Cancer Institute. Monographs. 69-78. PMID 7912532  1
1993 Sharma A, Mayhew E, Straubinger RM. Antitumor Effect of Taxol-containing Liposomes in a Taxol-resistant Murine Tumor Model Cancer Research. 53: 5877-5881. PMID 7903197  1
1990 Straubinger RM, Papahadjopoulos D, Hong K. Endocytosis and intracellular fate of liposomes using pyranine as a probe Biochemistry. 29: 4929-4939. PMID 2163672 DOI: 10.1021/bi00472a025  1
1990 Chin DJ, Green GA, Zon G, Szoka FC, Straubinger RM. Rapid nuclear accumulation of injected oligodeoxyribonucleotides New Biologist. 2: 1091-1100. PMID 1708281  1
1989 Matthay KK, Abai AM, Cobb S, Hong K, Papahadjopoulos D, Straubinger RM. Role of ligand in antibody-directed endocytosis of liposomes by human T-leukemia cells. Cancer Research. 49: 4879-86. PMID 2788031  1
1989 Chin DJ, Straubinger RM, Acton S, Nathke I, Brodsky FM. 100-kDa polypeptides in peripheral clathrin-coated vesicles are required for receptor-mediated endocytosis Proceedings of the National Academy of Sciences of the United States of America. 86: 9289-9293. PMID 2574457 DOI: 10.1073/pnas.86.23.9289  1
1988 Straubinger RM, Lopez NG, Debs RJ, Hong K, Papahadjopoulos D. Liposome-based Therapy of Human Ovarian Cancer: Parameters Determining Potency of Negatively Charged and Antibody-targeted Liposomes Cancer Research. 48: 5237-5245. PMID 3409248  1
1988 Gabizon A, Hliberty J, Straubinger RM, Price DC, Papahadjopoulos D. An improved method for in vivo tracing and imaging of liposomes using a gallium 67-deferoxamine complex Journal of Liposome Research. 1: 123-135. DOI: 10.3109/08982108809035986  1
1987 Debs RJ, Straubinger RM, Brunette EN, Lin JM, Lin EJ, Montgomery AB, Friend DS, Papahadjopoulos DP. Selective enhancement of pentamidine uptake in the lung by aerosolization and delivery in liposomes American Review of Respiratory Disease. 135: 731-737. PMID 3826898  1
1987 Debs RJ, Blumenfeld W, Brunette EN, Straubinger RM, Montgomery AB, Lin E, Agabian N, Papahadjopoulos D. Successful treatment with aerosolized pentamidine of Pneumocystis carinii pneumonia in rats. Antimicrobial Agents and Chemotherapy. 31: 37-41. PMID 3494424  1
1985 Düzgüneş N, Straubinger RM, Baldwin PA, Friend DS, Papahadjopoulos D. Proton-induced fusion of oleic acid-phosphatidylethanolamine liposomes Biochemistry. 24: 3091-3098. PMID 4027231  1
1985 Straubinger RM, Düzgünes N, Papahadjopoulos D. pH-sensitive liposomes mediate cytoplasmic delivery of encapsulated macromolecules Febs Letters. 179: 148-154. PMID 2578112 DOI: 10.1016/0014-5793(85)80210-6  1
1983 Straubinger RM, Hong K, Friend DS, Papahadjopoulos D. Endocytosis of liposomes and intracellular fate of encapsulated molecules: Encounter with a low pH compartment after internalization in coated vesicles Cell. 32: 1069-1079. PMID 6404557 DOI: 10.1016/0092-8674(83)90291-X  1
1983 Straubinger RM, Papahadjopoulos D. Liposomes as carriers for intracellular delivery of nucleic acids Methods in Enzymology. 512-527. PMID 6193396  1
1981 Fraley R, Straubinger RM, Rule G, Springer EL, Papahadjopoulos D. Liposome-mediated delivery of deoxyribonucleic acid to cells: enhanced efficiency of delivery related to lipid composition and incubation conditions. Biochemistry. 20: 6978-87. PMID 6274382 DOI: 10.1021/bi00527a031  1
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