Stavroula Sofou - Publications

Affiliations: 
Chemical and Biological Engineering Polytechnic Institute of New York University, Brooklyn, NY, NY, United States 
 Rutgers University, New Brunswick, New Brunswick, NJ, United States 
 Chemical and Biomolecular Engineering Johns Hopkins University, Baltimore, MD 
Area:
Chemical Engineering, Pharmacy, Oncology
Website:
https://engineering.jhu.edu/faculty/stavroula-sofou/

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Howe A, Bhatavdekar O, Salerno D, Josefsson A, Pacheco-Torres J, Bhujwalla ZM, Gabrielson KL, Sgouros G, Sofou S. Combination of carriers, with complementary intratumoral microdistributions of delivered α-particles, may realize the promise for Actinium-225 in large solid tumors. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 34795012 DOI: 10.2967/jnumed.121.262992  0.536
2021 Prasad A, Nair R, Bhatavdekar O, Howe A, Salerno D, Sempkowski M, Josefsson A, Pacheco-Torres J, Bhujwalla ZM, Gabrielson KL, Sgouros G, Sofou S. Transport-driven engineering of liposomes for delivery of α-particle radiotherapy to solid tumors: effect on inhibition of tumor progression and onset delay of spontaneous metastases. European Journal of Nuclear Medicine and Molecular Imaging. PMID 34117896 DOI: 10.1007/s00259-021-05406-z  0.536
2019 Stras S, Howe A, Prasad A, Salerno D, Bhatavdekar O, Sofou S. Growth of Metastatic Triple-Negative Breast Cancer Is Inhibited by Deep Tumor-Penetrating and Slow Tumor-Clearing Chemotherapy: The Case of Tumor-Adhering Liposomes with Interstitial Drug Release. Molecular Pharmaceutics. PMID 31825626 DOI: 10.1021/acs.molpharmaceut.9b00812  0.318
2019 Howe AK, Sofou S. Mechanistic Studies on Daptomycin-Induced Phase-Transitions on Model Lipid Membranes: Effect on Membrane Permeability Biophysical Journal. 116: 85a. DOI: 10.1016/J.Bpj.2018.11.502  0.379
2019 Ganesh Prasad A, Salerno D, Howe AK, Mandar Bhatavdekar O, Sofou S. Location-Location-Location: Designing Cationic Charge Placement on Lipid Vesicles Determines their Interactions with Living Cells Biophysical Journal. 116: 296a. DOI: 10.1016/J.Bpj.2018.11.1602  0.333
2018 Kowzun MJ, Rifkin WJ, Borab ZM, Ellison T, Soares MA, Wilson SC, Lotfi P, Bandekar A, Sofou S, Saadeh PB, Ceradini DJ. Topical inhibition of PUMA signaling mitigates radiation injury. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. PMID 30155987 DOI: 10.1111/Wrr.12668  0.711
2018 McDevitt MR, Sgouros G, Sofou S. Targeted and Nontargeted α-Particle Therapies. Annual Review of Biomedical Engineering. PMID 29345977 DOI: 10.1146/Annurev-Bioeng-062117-120931  0.497
2017 Locke T, Sofou S. Clustered vs. uniform display of GALA-peptides on carrier nanoparticles: enhancing the permeation of non-charged fluid lipid-membranes. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 29096061 DOI: 10.1021/Acs.Langmuir.7B03706  0.439
2017 Zhu C, Sempkowski M, Holleran T, Linz T, Bertalan T, Josefsson A, Bruchertseifer F, Morgenstern A, Sofou S. Alpha-particle radiotherapy: For large solid tumors diffusion trumps targeting. Biomaterials. 130: 67-75. PMID 28365545 DOI: 10.1016/J.Biomaterials.2017.03.035  0.42
2016 Stras S, Holleran T, Howe A, Sofou S. Interstitial Release of Cisplatin from Triggerable Liposomes Enhances Efficacy Against Triple Negative Breast Cancer Solid Tumor Analogues. Molecular Pharmaceutics. PMID 27482716 DOI: 10.1021/Acs.Molpharmaceut.6B00439  0.505
2016 Sempkowski M, Zhu C, Menzenski MZ, Kevrekidis IG, Bruchertseifer F, Morgenstern A, Sofou S. Sticky Patches on Lipid Nanoparticles Enable Selective Targeting and Killing of Untargetable Cancer Cells. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 27468779 DOI: 10.1021/Acs.Langmuir.6B01464  0.43
2015 Zhu C, Bandekar A, Sempkowski M, Ray Banerjee S, Pomper MG, Bruchertseifer F, Morgenstern A, Sofou S. Nanoconjugation of PSMA-targeting ligands enhances perinuclear localization and improves efficacy of delivered alpha-particle emitters against tumor endothelial analogues. Molecular Cancer Therapeutics. PMID 26586724 DOI: 10.1158/1535-7163.Mct-15-0207  0.777
2015 Curtis EM, Xiao X, Sofou S, Hall CK. Phase separation behavior of mixed lipid systems at neutral and low pH: coarse-grained simulations with DMD/LIME. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 1086-94. PMID 25549801 DOI: 10.1021/La504082X  0.423
2015 Sempkowski M, Kevrekidis Y, Sofou S. Sticky Patches on Lipid Nanoparticles Generate Binding Geometries that Enable Effective Targeting of Otherwise Untargetable Cancers Biophysical Journal. 108: 345a. DOI: 10.1016/J.Bpj.2014.11.1889  0.475
2014 Sempkowski M, Locke T, Stras S, Zhu C, Sofou S. Liposome-based approaches for delivery of mainstream chemotherapeutics: preparation methods, liposome designs, therapeutic efficacy. Critical Reviews in Oncogenesis. 19: 177-221. PMID 25271431 DOI: 10.1615/Critrevoncog.2014011533  0.397
2014 Bandekar A, Zhu C, Jindal R, Bruchertseifer F, Morgenstern A, Sofou S. Anti-prostate-specific membrane antigen liposomes loaded with 225Ac for potential targeted antivascular α-particle therapy of cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 107-14. PMID 24337602 DOI: 10.2967/Jnumed.113.125476  0.759
2013 Bandekar A, Zhu C, Gomez A, Menzenski MZ, Sempkowski M, Sofou S. Masking and triggered unmasking of targeting ligands on liposomal chemotherapy selectively suppress tumor growth in vivo. Molecular Pharmaceutics. 10: 152-60. PMID 23134440 DOI: 10.1021/Mp3002717  0.822
2013 Bandekar A, Sofou S. Anti-PSMA liposomes loaded with actinium-225 for potential targeted antivascular alpha particle therapy of cancer Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 111.  0.739
2012 Bandekar A, Karve S, Chang MY, Mu Q, Rotolo J, Sofou S. Antitumor efficacy following the intracellular and interstitial release of liposomal doxorubicin. Biomaterials. 33: 4345-52. PMID 22429980 DOI: 10.1016/J.Biomaterials.2012.02.039  0.81
2012 Bandekar A, Sofou S. Floret-shaped solid domains on giant fluid lipid vesicles induced by pH. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 4113-22. PMID 22276950 DOI: 10.1021/La204765R  0.766
2012 Bhagat M, Halligan S, Sofou S. Nanocarriers to solid tumors: considerations on tumor penetration and exposure of tumor cells to therapeutic agents. Current Pharmaceutical Biotechnology. 13: 1306-16. PMID 22201591 DOI: 10.2174/138920112800624256  0.762
2011 Mamasheva E, O'Donnell C, Bandekar A, Sofou S. Heterogeneous liposome membranes with pH-triggered permeability enhance the in vitro antitumor activity of folate-receptor targeted liposomal doxorubicin. Molecular Pharmaceutics. 8: 2224-32. PMID 21899300 DOI: 10.1021/Mp200079Y  0.811
2010 Karve S, Bandekar A, Ali MR, Sofou S. The pH-dependent association with cancer cells of tunable functionalized lipid vesicles with encapsulated doxorubicin for high cell-kill selectivity. Biomaterials. 31: 4409-16. PMID 20189243 DOI: 10.1016/J.Biomaterials.2010.01.064  0.802
2010 Sofou S, Enmon R, Palm S, Kappel B, Zanzonico P, McDevitt MR, Scheinberg DA, Sgouros G. Large anti-HER2/neu liposomes for potential targeted intraperitoneal therapy of micrometastatic cancer. Journal of Liposome Research. 20: 330-40. PMID 20070139 DOI: 10.3109/08982100903544185  0.686
2010 Bhagat M, Sofou S. Membrane heterogeneities and fusogenicity in phosphatidylcholine-phosphatidic acid rigid vesicles as a function of pH and lipid chain mismatch. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 1666-73. PMID 19813725 DOI: 10.1021/La9026283  0.779
2009 Karve S, Alaouie A, Zhou Y, Rotolo J, Sofou S. The use of pH-triggered leaky heterogeneities on rigid lipid bilayers to improve intracellular trafficking and therapeutic potential of targeted liposomal immunochemotherapy. Biomaterials. 30: 6055-64. PMID 19665223 DOI: 10.1016/J.Biomaterials.2009.07.038  0.754
2009 Kempegowda GB, Karve S, Bandekar A, Adhikari A, Khaimchayev T, Sofou S. pH-dependent formation of lipid heterogeneities controls surface topography and binding reactivity in functionalized bilayers. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 8144-51. PMID 19594187 DOI: 10.1021/La9004032  0.788
2008 Sofou S. Radionuclide carriers for targeting of cancer. International Journal of Nanomedicine. 3: 181-99. PMID 18686778 DOI: 10.2147/Ijn.S2736  0.439
2008 Sofou S, Yu YB. Delivery systems for the targeted radiotherapy of cancer. Preface. Advanced Drug Delivery Reviews. 60: 1317-8. PMID 18538443 DOI: 10.1016/J.Addr.2008.04.004  0.381
2008 Chang MY, Seideman J, Sofou S. Enhanced loading efficiency and retention of 225Ac in rigid liposomes for potential targeted therapy of micrometastases. Bioconjugate Chemistry. 19: 1274-82. PMID 18505278 DOI: 10.1021/Bc700440A  0.445
2008 Karve S, Bajagur Kempegowda G, Sofou S. Heterogeneous domains and membrane permeability in phosphatidylcholine-phosphatidic acid rigid vesicles as a function of pH and lipid chain mismatch. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 5679-88. PMID 18471003 DOI: 10.1021/La800331A  0.733
2008 Sofou S, Sgouros G. Antibody-targeted liposomes in cancer therapy and imaging. Expert Opinion On Drug Delivery. 5: 189-204. PMID 18248318 DOI: 10.1517/17425247.5.2.189  0.587
2008 Alaouie AM, Sofou S. Liposomes with triggered content release for cancer therapy Journal of Biomedical Nanotechnology. 4: 234-244. DOI: 10.1166/Jbn.2008.335  0.478
2008 Bhagat M, Sofou S. Fusion studies of charged heterogeneous membranes: Effect of pH and cholesterol Aiche Annual Meeting, Conference Proceedings 0.327
2008 Karve S, Gowda G, Sofou S. Heterogeneous domains and membrane permeability in phosphatidylcholine- phosphatidic acid rigid vesicles as a function of ph and lipid chain mismatch Aiche Annual Meeting, Conference Proceedings 0.662
2008 Karve S, Alaouie A, Sofou S. Anti-HER2/neu liposomes for triggered content release in ovarian and breast cancer cells Aiche Annual Meeting, Conference Proceedings 0.607
2008 Bandekar A, Karve S, Sofou S. pH-triggerable liposomes for delivery and release of doxorubicin Aiche Annual Meeting, Conference Proceedings 0.78
2007 Sofou S. Surface-active liposomes for targeted cancer therapy. Nanomedicine (London, England). 2: 711-24. PMID 17976032 DOI: 10.2217/17435889.2.5.711  0.437
2007 Sofou S, Kappel BJ, Jaggi JS, McDevitt MR, Scheinberg DA, Sgouros G. Enhanced retention of the α-particle-emitting daughters of actinium-225 by liposome carriers Bioconjugate Chemistry. 18: 2061-2067. PMID 17935286 DOI: 10.1021/Bc070075T  0.614
2006 Karve S, Sofou S. Rigid-liposomes with engineered 'raft-switches' for controlled release of therapeutics Aiche Annual Meeting, Conference Proceedings 0.595
2005 Huang CC, Chang MY, Karve S, Sofou S. Engineered lipid-based 'polysomes' for targeted multimodal therapy of disseminated metastatic cancer Aiche Annual Meeting, Conference Proceedings. 8863.  0.642
2004 Sofou S, Thomas JL, Lin HY, McDevitt MR, Scheinberg DA, Sgouros G. Engineered liposomes for potential alpha-particle therapy of metastatic cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 45: 253-60. PMID 14960644  0.631
2003 Sofou S, Thomas JL. Stable adhesion of phospholipid vesicles to modified gold surfaces. Biosensors & Bioelectronics. 18: 445-55. PMID 12604262 DOI: 10.1016/S0956-5663(02)00153-7  0.527
2003 Sofou S, Thomas JL. Effects of oxidation and reduction on the membrane activity of a cysteine dimerizable peptide Colloids and Surfaces B: Biointerfaces. 27: 197-207. DOI: 10.1016/S0927-7765(02)00068-1  0.367
2002 Sofou S, Thomas JL. Stable adsorption of lipid vesicles on modified gold surfaces Materials Research Society Symposium - Proceedings. 705: 171-176. DOI: 10.1557/Proc-705-Y6.3  0.339
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