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Lawrence M. Szewczuk, Ph.D. - Publications

Affiliations: 
2004 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biochemistry, Medical Biophysics
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Machutta CA, Kollmann CS, Lind KE, Bai X, Chan PF, Huang J, Ballell L, Belyanskaya S, Besra GS, Barros-Aguirre D, Bates RH, Centrella PA, Chang SS, Chai J, Choudhry AE, ... ... Szewczuk LM, et al. Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening. Nature Communications. 8: 16081. PMID 28714473 DOI: 10.1038/Ncomms16081  0.306
2009 Szewczuk LM, Penning TM. Co-oxidation by cyclooxygenases. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit4.30. PMID 23045015 DOI: 10.1002/0471140856.Tx0430S42  0.385
2005 Park JH, Gopishetty S, Szewczuk LM, Troxel AB, Harvey RG, Penning TM. Formation of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxo-dGuo) by PAH o-quinones: involvement of reactive oxygen species and copper(II)/copper(I) redox cycling. Chemical Research in Toxicology. 18: 1026-37. PMID 15962938 DOI: 10.1021/Tx050001A  0.388
2005 Szewczuk LM, Lee SH, Blair IA, Penning TM. Viniferin formation by COX-1: evidence for radical intermediates during co-oxidation of resveratrol. Journal of Natural Products. 68: 36-42. PMID 15679314 DOI: 10.1021/Np049702I  0.437
2005 Bauman DR, Rudnick SI, Szewczuk LM, Jin Y, Gopishetty S, Penning TM. Development of nonsteroidal anti-inflammatory drug analogs and steroid carboxylates selective for human aldo-keto reductase isoforms: potential antineoplastic agents that work independently of cyclooxygenase isozymes. Molecular Pharmacology. 67: 60-8. PMID 15475569 DOI: 10.1124/Mol.104.006569  0.419
2004 Szewczuk LM, Penning TM. Mechanism-based inactivation of COX-1 by red wine m-hydroquinones: a structure-activity relationship study. Journal of Natural Products. 67: 1777-82. PMID 15568761 DOI: 10.1021/Np0498410  0.438
2004 Szewczuk LM, Forti L, Stivala LA, Penning TM. Resveratrol is a peroxidase-mediated inactivator of COX-1 but not COX-2: a mechanistic approach to the design of COX-1 selective agents. The Journal of Biological Chemistry. 279: 22727-37. PMID 15020596 DOI: 10.1074/Jbc.M314302200  0.475
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