Year |
Citation |
Score |
2023 |
Dhungel L, Harris C, Romine L, Sarkaria J, Raucher D. Targeted c-Myc Inhibition and Systemic Temozolomide Therapy Extend Survival in Glioblastoma Xenografts. Bioengineering (Basel, Switzerland). 10. PMID 37370649 DOI: 10.3390/bioengineering10060718 |
0.388 |
|
2022 |
Dragojevic S, Turner L, Pal P, Janorkar AV, Raucher D. Elastin-like Polypeptide Hydrogels for Tunable, Sustained Local Chemotherapy in Malignant Glioma. Pharmaceutics. 14. PMID 36297507 DOI: 10.3390/pharmaceutics14102072 |
0.353 |
|
2022 |
Dragojevic S, Ryu JS, Hall ME, Raucher D. Targeted Drug Delivery Biopolymers Effectively Inhibit Breast Tumor Growth and Prevent Doxorubicin-Induced Cardiotoxicity. Molecules (Basel, Switzerland). 27. PMID 35684309 DOI: 10.3390/molecules27113371 |
0.462 |
|
2022 |
Dragojevic S, Turner L, Raucher D. Circumventing Doxorubicin Resistance Using Elastin-like Polypeptide Biopolymer-Mediated Drug Delivery. International Journal of Molecular Sciences. 23. PMID 35216417 DOI: 10.3390/ijms23042301 |
0.378 |
|
2021 |
Ryu JS, Kratz F, Raucher D. Cell-Penetrating Doxorubicin Released from Elastin-Like Polypeptide Kills Doxorubicin-Resistant Cancer Cells in In Vitro Study. International Journal of Molecular Sciences. 22. PMID 33498762 DOI: 10.3390/ijms22031126 |
0.426 |
|
2020 |
Thomas E, Dragojevic S, Price A, Raucher D. Thermally Targeted p50 Peptide Inhibits Proliferation and Induces Apoptosis of Breast Cancer Cell Lines. Macromolecular Bioscience. e2000170. PMID 32734662 DOI: 10.1002/Mabi.202000170 |
0.603 |
|
2020 |
Das P, Boone S, Mitra D, Turner L, Tandon R, Raucher D, Hamme AT. Synthesis and biological evaluation of fluoro-substituted spiro-isoxazolines as potential anti-viral and anti-cancer agents Rsc Advances. 10: 30223-30237. DOI: 10.1039/D0Ra06148D |
0.347 |
|
2019 |
Dragojevic S, Mackey R, Raucher D. Evaluation of Elastin-Like Polypeptides for Tumor Targeted Delivery of Doxorubicin to Glioblastoma. Molecules (Basel, Switzerland). 24. PMID 31489879 DOI: 10.3390/Molecules24183242 |
0.568 |
|
2019 |
Das P, Hasan MH, Mitra D, Bollavarapu R, Valente EJ, Tandon R, Raucher D, Hamme AT. Design, Synthesis, and Preliminary Studies of Spiro-Isoxazoline-Peroxides against Human-Cytomegalovirus (HCMV) and Glioblastoma (GBM6)∥. The Journal of Organic Chemistry. PMID 31066280 DOI: 10.1021/Acs.Joc.9B00746 |
0.327 |
|
2019 |
Raucher D. Tumor targeting peptides: novel therapeutic strategies in glioblastoma. Current Opinion in Pharmacology. 47: 14-19. PMID 30776641 DOI: 10.1016/J.Coph.2019.01.006 |
0.566 |
|
2019 |
Ryu JS, Robinson L, Raucher D. Elastin-Like Polypeptide Delivers a Notch Inhibitory Peptide to Inhibit Tumor Growth in Combination with Paclitaxel. Journal of Chemotherapy (Florence, Italy). 31: 23-29. PMID 30773131 DOI: 10.1080/1120009X.2018.1537554 |
0.563 |
|
2018 |
Raucher D, Dragojevic S, Ryu J. Macromolecular Drug Carriers for Targeted Glioblastoma Therapy: Preclinical Studies, Challenges, and Future Perspectives. Frontiers in Oncology. 8: 624. PMID 30619758 DOI: 10.3389/Fonc.2018.00624 |
0.516 |
|
2018 |
Dragojevic S, Mackey RB, Kratz F, Raucher D. Abstract 3708: Targeted delivery of doxorubicin to glioblastomas by thermally sensitive polypeptides Cancer Research. 78: 3708-3708. DOI: 10.1158/1538-7445.Am2018-3708 |
0.552 |
|
2017 |
Opačak-Bernardi T, Ryu JS, Raucher D. Effects of cell penetrating Notch inhibitory peptide conjugated to elastin-like polypeptide on glioblastoma cells. Journal of Drug Targeting. 1-28. PMID 28140690 DOI: 10.1080/1061186X.2017.1289537 |
0.574 |
|
2017 |
Ryu JS, Raucher D. Abstract 5129: Cell-penetrating doxorubicin released from Elastin-like polypeptide kills doxorubicin-resistant cancer cells Cancer Research. 77: 5129-5129. DOI: 10.1158/1538-7445.Am2017-5129 |
0.573 |
|
2017 |
Dragojevic S, Ryu JS, Kratz F, Raucher D. Abstract 3106: Targeted delivery via Elastin Like Polypeptide: Biodistribution of a doxorubicin derivative in MDA-MB231 human breast cancer xenografts in mice Cancer Research. 77: 3106-3106. DOI: 10.1158/1538-7445.Am2017-3106 |
0.384 |
|
2016 |
Dragojevic S, Ryu JS, Kratz F, Raucher D. Abstract 2168: Optimizing doxorubicin derivatives delivery using temperature sensitive biopolymers in multidrug resistant breast cancer cells Cancer Research. 76: 2168-2168. DOI: 10.1158/1538-7445.Am2016-2168 |
0.5 |
|
2016 |
Ryu JS, Raucher D. Abstract 2072: Inhibition of breast cancer stem cells by Hedgehog-inhibitory peptide conjugated with Elastin-like biopolymers Cancer Research. 76: 2072-2072. DOI: 10.1158/1538-7445.Am2016-2072 |
0.451 |
|
2016 |
Opacak-Bernardi T, Ryu J, Raucher D. Thermally responsive ELP-dnMAML protein and its effect on U251 cells in vitro European Journal of Cancer. 61: S110. DOI: 10.1016/S0959-8049(16)61390-4 |
0.355 |
|
2016 |
Raucher D, Ryu J, Dragojevic S. Elastin-like polypeptide for Improved delivery of small molecule drugs and therapeutic peptides for anticancer therapy European Journal of Cancer. 69: S66-S67. DOI: 10.1016/S0959-8049(16)32787-3 |
0.37 |
|
2015 |
Dragojevic S, Ryu JS, Raucher D. Polymer-Based Prodrugs: Improving Tumor Targeting and the Solubility of Small Molecule Drugs in Cancer Therapy. Molecules (Basel, Switzerland). 20: 21750-69. PMID 26690101 DOI: 10.3390/Molecules201219804 |
0.418 |
|
2015 |
Raucher D, Ryu JS. Cell-penetrating peptides: strategies for anticancer treatment. Trends in Molecular Medicine. PMID 26186888 DOI: 10.1016/J.Molmed.2015.06.005 |
0.598 |
|
2015 |
Das P, Omollo AO, Sitole LJ, McClendon E, Valente EJ, Raucher D, Walker LR, Hamme AT. Synthesis and Investigation of Novel Spiro-isoxazolines as Anti-Cancer Agents. Tetrahedron Letters. 56: 1794-1797. PMID 25821250 DOI: 10.1016/J.Tetlet.2015.02.059 |
0.582 |
|
2015 |
Ryu JS, Raucher D. Elastin-like polypeptide for improved drug delivery for anticancer therapy: preclinical studies and future applications. Expert Opinion On Drug Delivery. 12: 653-67. PMID 25350837 DOI: 10.1517/17425247.2015.974546 |
0.513 |
|
2015 |
Kuna M, Raucher D. Abstract 5524: Comparison of c-Myc inhibitor effectiveness in various cancer cell lines Cancer Research. 75: 5524-5524. DOI: 10.1158/1538-7445.Am2015-5524 |
0.528 |
|
2014 |
Walker LR, Ryu JS, Perkins E, McNally LR, Raucher D. Fusion of cell-penetrating peptides to thermally responsive biopolymer improves tumor accumulation of p21 peptide in a mouse model of pancreatic cancer. Drug Design, Development and Therapy. 8: 1649-58. PMID 25336913 DOI: 10.2147/Dddt.S60451 |
0.729 |
|
2014 |
Hearst SM, Shao Q, Lopez M, Raucher D, Vig PJ. The design and delivery of a PKA inhibitory polypeptide to treat SCA1. Journal of Neurochemistry. 131: 101-14. PMID 24903464 DOI: 10.1111/Jnc.12782 |
0.495 |
|
2014 |
Ryu JS, Raucher D. Elastin-like polypeptides: the influence of its molecular weight on local hyperthermia-induced tumor accumulation. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 88: 382-9. PMID 24866938 DOI: 10.1016/J.Ejpb.2014.05.016 |
0.538 |
|
2014 |
Ryu JS, Kuna M, Raucher D. Penetrating the cell membrane, thermal targeting and novel anticancer drugs: the development of thermally targeted, elastin-like polypeptide cancer therapeutics. Therapeutic Delivery. 5: 429-45. PMID 24856169 DOI: 10.4155/Tde.14.14 |
0.626 |
|
2014 |
Ryu JS, Raucher D. Anti-tumor efficacy of a therapeutic peptide based on thermo-responsive elastin-like polypeptide in combination with gemcitabine. Cancer Letters. 348: 177-84. PMID 24680816 DOI: 10.1016/J.Canlet.2014.03.021 |
0.589 |
|
2014 |
Lyons DF, Le V, Kramer WH, Bidwell GL, Lewis EA, Raucher D, Correia JJ. Effect of basic cell-penetrating peptides on the structural, thermodynamic, and hydrodynamic properties of a novel drug delivery vector, ELP[V5G3A2-150]. Biochemistry. 53: 1081-91. PMID 24450599 DOI: 10.1021/Bi400955W |
0.723 |
|
2014 |
Mikecin AM, Walker LR, Kuna M, Raucher D. Thermally targeted p21 peptide enhances bortezomib cytotoxicity in androgen-independent prostate cancer cell lines. Anti-Cancer Drugs. 25: 189-99. PMID 24113592 DOI: 10.1097/Cad.0000000000000036 |
0.61 |
|
2013 |
Lyons DF, Le V, Bidwell GL, Kramer WH, Lewis EA, Raucher D, Correia JJ. Structural and hydrodynamic analysis of a novel drug delivery vector: ELP[V5G3A2-150]. Biophysical Journal. 104: 2009-21. PMID 23663844 DOI: 10.1016/J.Bpj.2013.03.040 |
0.681 |
|
2013 |
Bidwell GL, Perkins E, Hughes J, Khan M, James JR, Raucher D. Thermally targeted delivery of a c-Myc inhibitory polypeptide inhibits tumor progression and extends survival in a rat glioma model. Plos One. 8: e55104. PMID 23372821 DOI: 10.1371/Journal.Pone.0055104 |
0.75 |
|
2013 |
Bidwell GL, Perkins E, Hughes J, Khan M, James JR, Raucher D. Biodistribution of CPP-ELPs Following IV Injection. Plos One. DOI: 10.1371/Journal.Pone.0055104.G002 |
0.578 |
|
2013 |
Walker LR, Perkins E, Ajaj KA, Kratz F, Raucher D. Abstract 4507: Utilizing the targeting properties of elastin-like polypeptide to safely deliver a potent doxorubicin derivative. Cancer Research. 73: 4507-4507. DOI: 10.1158/1538-7445.Am2013-4507 |
0.725 |
|
2013 |
Ryu JS, Mikecin A, Raucher D. Abstract 2062: The effects of a cell cycle inhibitory peptide fused to elastin-like polypeptide on pancreatic cancer cells with hyperthermia and its combination with gemcitabine. Cancer Research. 73: 2062-2062. DOI: 10.1158/1538-7445.Am2013-2062 |
0.593 |
|
2013 |
Lyons D, Le V, Bidwell GL, Kramer W, Lewis E, Raucher D, Correia JJ. Biophysical Analysis of a Novel Drug Delivery Vector: ELP[V5G3A2-150] Biophysical Journal. 104: 552a-553a. DOI: 10.1016/J.Bpj.2012.11.3065 |
0.645 |
|
2012 |
Tullos H, Dale B, Bidwell G, Perkins E, Raucher D, Khan M, James J. SU-E-I-67: Multi-Shot RESOLVE Compared to Single-Shot EPI Diffusion- Weighted MR Imaging Acquisition Scheme. Medical Physics. 39: 3640. PMID 28517668 DOI: 10.1118/1.4734783 |
0.557 |
|
2012 |
Moktan S, Raucher D. Anticancer activity of proapoptotic peptides is highly improved by thermal targeting using elastin-like polypeptides. International Journal of Peptide Research and Therapeutics. 18: 227-237. PMID 23105921 DOI: 10.1007/S10989-012-9295-Y |
0.84 |
|
2012 |
Walker L, Perkins E, Kratz F, Raucher D. Cell penetrating peptides fused to a thermally targeted biopolymer drug carrier improve the delivery and antitumor efficacy of an acid-sensitive doxorubicin derivative. International Journal of Pharmaceutics. 436: 825-32. PMID 22850291 DOI: 10.1016/J.Ijpharm.2012.07.043 |
0.736 |
|
2012 |
Moktan S, Perkins E, Kratz F, Raucher D. Thermal targeting of an acid-sensitive doxorubicin conjugate of elastin-like polypeptide enhances the therapeutic efficacy compared with the parent compound in vivo. Molecular Cancer Therapeutics. 11: 1547-56. PMID 22532601 DOI: 10.1158/1535-7163.Mct-11-0998 |
0.826 |
|
2012 |
Bidwell GL, Perkins E, Raucher D. A thermally targeted c-Myc inhibitory polypeptide inhibits breast tumor growth. Cancer Letters. 319: 136-43. PMID 22261328 DOI: 10.1016/J.Canlet.2011.12.042 |
0.755 |
|
2012 |
Moktan S, Ryppa C, Kratz F, Raucher D. A thermally responsive biopolymer conjugated to an acid-sensitive derivative of paclitaxel stabilizes microtubules, arrests cell cycle, and induces apoptosis. Investigational New Drugs. 30: 236-48. PMID 20938714 DOI: 10.1007/S10637-010-9560-X |
0.818 |
|
2012 |
Bidwell, III G, Perkins E, Hughes J, Khan M, James J, Raucher D. Treatment of Malignant Gliomas Using Thermally Targeted Peptide Therapeutics (SC02.007) Neurology. 78: SC02.007-SC02.007. DOI: 10.1212/Wnl.78.1_Meetingabstracts.Sc02.007 |
0.489 |
|
2012 |
Ryu JS, Raucher D. Abstract 5707: The EPR effects of Elastin-like polypeptide of differnt molecular sizes in animal tumor models Cancer Research. 72: 5707-5707. DOI: 10.1158/1538-7445.Am2012-5707 |
0.535 |
|
2012 |
Walker LR, Kratz F, Raucher D. Abstract 4771: Improved antitumor efficacy of an acid-sensitive doxorubicin derivative delivered by thermally responsive elastin-like polypeptides Cancer Research. 72: 4771-4771. DOI: 10.1158/1538-7445.Am2012-4771 |
0.725 |
|
2012 |
Walker LR, Perkins E, McNally L, Raucher D. Abstract 355: Comparison of biodistribution and accumulation of a thermally responsive polypeptide with and without a cell-penetrating peptide Cancer Research. 72: 355-355. DOI: 10.1158/1538-7445.Am2012-355 |
0.714 |
|
2011 |
Hearst SM, Walker LR, Shao Q, Lopez M, Raucher D, Vig PJ. The design and delivery of a thermally responsive peptide to inhibit S100B-mediated neurodegeneration. Neuroscience. 197: 369-80. PMID 21958864 DOI: 10.1016/J.Neuroscience.2011.09.025 |
0.69 |
|
2011 |
Robinson L, Perkins E, McNally L, Raucher D. Abstract 5292: Tumor accumulation and biodistribution of a thermally responsive cell cycle inhibitory polypeptidein vivo Cancer Research. 71: 5292-5292. DOI: 10.1158/1538-7445.Am2011-5292 |
0.569 |
|
2011 |
Moktan S, Perkins E, Kratz F, Raucher D. Abstract 4440: Anti-tumor activity of a thermally responsive polypeptide-doxorubicin conjugate in a syngeneic mouse breast cancer model Cancer Research. 71: 4440-4440. DOI: 10.1158/1538-7445.Am2011-4440 |
0.82 |
|
2011 |
Bidwell GL, Perkins E, Raucher D. Abstract 4434: Thermally targeted delivery of a c-Myc inhibitory peptide to breast tumors in vivo using elastin-like polypeptide Cancer Research. 71: 4434-4434. DOI: 10.1158/1538-7445.Am2011-4434 |
0.737 |
|
2011 |
Opacak-Bernardi T, Robinson L, Ajaj KA, Kratz F, Raucher D. Abstract 3226: In vitro evaluation of a thermally targeted conjugate of a highly potent doxorubicin derivative Cancer Research. 71: 3226-3226. DOI: 10.1158/1538-7445.Am2011-3226 |
0.614 |
|
2011 |
Lyons D, Bidwell GL, Kramer WH, Raucher D, Correia JJ. Biophysical Characterization of an Elastin-Like-Polypeptide Biophysical Journal. 100: 540a. DOI: 10.1016/J.Bpj.2010.12.3148 |
0.666 |
|
2011 |
Raucher D, Moktan S. Thermo-Responsive Polymers Drug Delivery in Oncology: From Basic Research to Cancer Therapy. 2: 667-700. DOI: 10.1002/9783527634057.ch22 |
0.706 |
|
2010 |
Bidwell GL, Raucher D. Cell penetrating elastin-like polypeptides for therapeutic peptide delivery. Advanced Drug Delivery Reviews. 62: 1486-96. PMID 20478348 DOI: 10.1016/J.Addr.2010.05.003 |
0.776 |
|
2010 |
Bidwell GL, Whittom AA, Thomas E, Lyons D, Hebert MD, Raucher D. A thermally targeted peptide inhibitor of symmetrical dimethylation inhibits cancer-cell proliferation. Peptides. 31: 834-41. PMID 20167239 DOI: 10.1016/J.Peptides.2010.02.007 |
0.698 |
|
2010 |
Massodi I, Moktan S, Rawat A, Bidwell GL, Raucher D. Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier. International Journal of Cancer. 126: 533-44. PMID 19588502 DOI: 10.1002/Ijc.24725 |
0.809 |
|
2010 |
Moktan S, Raucher D. Abstract 5520: Thermally targeted proapoptotic peptide for cancer therapy Cancer Research. 70: 5520-5520. DOI: 10.1158/1538-7445.Am10-5520 |
0.844 |
|
2010 |
Bidwell GL, Hughes J, Perkins E, Raucher D. Abstract 5516: A cell penetrating c-Myc inhibitory polypeptide accumulates in brain tumors in rats and inhibits tumor growth Cancer Research. 70: 5516-5516. DOI: 10.1158/1538-7445.Am10-5516 |
0.746 |
|
2010 |
Thomas EH, Raucher D. Abstract 2659: A thermally targeted carrier of p50 NLS peptide inhibits cancer cell proliferation by preventing NFκB nuclear translocation Cancer Research. 70: 2659-2659. DOI: 10.1158/1538-7445.Am10-2659 |
0.538 |
|
2010 |
Robinson L, Kratz F, Raucher D. Abstract 2653: Thermally targeted delivery of an acid-labile derivative of doxorubicin by elastin-like polypeptide Cancer Research. 70: 2653-2653. DOI: 10.1158/1538-7445.Am10-2653 |
0.612 |
|
2009 |
Raucher D, Moktan S, Massodi I, Bidwell GL. Therapeutic peptides for cancer therapy. Part II - cell cycle inhibitory peptides and apoptosis-inducing peptides. Expert Opinion On Drug Delivery. 6: 1049-64. PMID 19743895 DOI: 10.1517/17425240903158909 |
0.793 |
|
2009 |
Bidwell GL, Raucher D. Therapeutic peptides for cancer therapy. Part I - peptide inhibitors of signal transduction cascades. Expert Opinion On Drug Delivery. 6: 1033-47. PMID 19637980 DOI: 10.1517/17425240903143745 |
0.724 |
|
2009 |
Massodi I, Thomas E, Raucher D. Application of thermally responsive elastin-like polypeptide fused to a lactoferrin-derived peptide for treatment of pancreatic cancer. Molecules (Basel, Switzerland). 14: 1999-2015. PMID 19513001 DOI: 10.3390/Molecules14061999 |
0.828 |
|
2009 |
Massodi I, Bidwell GL, Davis A, Tausend A, Credit K, Flessner M, Raucher D. Inhibition of ovarian cancer cell metastasis by a fusion polypeptide Tat-ELP. Clinical & Experimental Metastasis. 26: 251-60. PMID 19169893 DOI: 10.1007/S10585-009-9237-Z |
0.796 |
|
2009 |
Bidwell GL, Davis AN, Raucher D. Targeting a c-Myc inhibitory polypeptide to specific intracellular compartments using cell penetrating peptides. Journal of Controlled Release : Official Journal of the Controlled Release Society. 135: 2-10. PMID 19095020 DOI: 10.1016/j.jconrel.2008.11.015 |
0.739 |
|
2008 |
Raucher D, Massodi I, Bidwell GL. Thermally targeted delivery of chemotherapeutics and anti-cancer peptides by elastin-like polypeptide. Expert Opinion On Drug Delivery. 5: 353-69. PMID 18318656 DOI: 10.1517/17425247.5.3.353 |
0.827 |
|
2007 |
Massodi I, Raucher D. A thermally responsive Tat-elastin-like polypeptide fusion protein induces membrane leakage, apoptosis, and cell death in human breast cancer cells. Journal of Drug Targeting. 15: 611-22. PMID 17968715 DOI: 10.1080/10611860701502780 |
0.817 |
|
2007 |
Bidwell GL, Davis AN, Fokt I, Priebe W, Raucher D. A thermally targeted elastin-like polypeptide-doxorubicin conjugate overcomes drug resistance. Investigational New Drugs. 25: 313-26. PMID 17483874 DOI: 10.1007/S10637-007-9053-8 |
0.67 |
|
2007 |
Bidwell GL, Fokt I, Priebe W, Raucher D. Development of elastin-like polypeptide for thermally targeted delivery of doxorubicin. Biochemical Pharmacology. 73: 620-31. PMID 17161827 DOI: 10.1016/J.Bcp.2006.10.028 |
0.75 |
|
2006 |
Bidwell GL, Raucher D. Enhancing the antiproliferative effect of topoisomerase II inhibitors using a polypeptide inhibitor of c-Myc. Biochemical Pharmacology. 71: 248-56. PMID 16316634 DOI: 10.1016/J.Bcp.2005.10.041 |
0.689 |
|
2005 |
Massodi I, Bidwell GL, Raucher D. Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 108: 396-408. PMID 16157413 DOI: 10.1016/J.Jconrel.2005.08.007 |
0.817 |
|
2005 |
Bidwell GL, Raucher D. Application of thermally responsive polypeptides directed against c-Myc transcriptional function for cancer therapy. Molecular Cancer Therapeutics. 4: 1076-85. PMID 16020665 DOI: 10.1158/1535-7163.Mct-04-0253 |
0.723 |
|
2003 |
Dreher MR, Raucher D, Balu N, Michael Colvin O, Ludeman SM, Chilkoti A. Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 91: 31-43. PMID 12932635 DOI: 10.1016/S0168-3659(03)00216-5 |
0.437 |
|
2002 |
Chilkoti A, Dreher MR, Meyer DE, Raucher D. Targeted drug delivery by thermally responsive polymers. Advanced Drug Delivery Reviews. 54: 613-30. PMID 12204595 DOI: 10.1016/S0169-409X(02)00041-8 |
0.504 |
|
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