Jacob D. Estes, Ph.D. - Publications

Affiliations: 
2003 Brigham Young University, Provo, UT, United States 
Area:
Microbiology Biology, Molecular Biology, Pathology, Immunology

190 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dubé M, Tastet O, Dufour C, Sannier G, Brassard N, Delgado GG, Pagliuzza A, Richard C, Nayrac M, Routy JP, Prat A, Estes JD, Fromentin R, Chomont N, Kaufmann DE. Spontaneous HIV expression during suppressive ART is associated with the magnitude and function of HIV-specific CD4 and CD8 T cells. Cell Host & Microbe. 31: 1507-1522.e5. PMID 37708853 DOI: 10.1016/j.chom.2023.08.006  0.472
2023 Viox EG, Hoang TN, Upadhyay AA, Nchioua R, Hirschenberger M, Strongin Z, Tharp GK, Pino M, Nguyen K, Harper JL, Gagne M, Marciano S, Boddapati AK, Pellegrini KL, Pradhan A, ... ... Estes JD, et al. Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques. Science Immunology. 8: eadg0033. PMID 37506197 DOI: 10.1126/sciimmunol.adg0033  0.314
2023 Angelovich TA, Cochrane CR, Zhou J, Tumpach C, Byrnes SJ, Jamal Eddine J, Waring E, Busman-Sahay K, Deleage C, Jenkins TA, Hearps AC, Turville S, Gorry PR, Lewin SR, Brew BJ, ... Estes JD, et al. Regional Analysis of Intact and Defective HIV Proviruses in the Brain of Viremic and Virally Suppressed People with HIV. Annals of Neurology. PMID 37493435 DOI: 10.1002/ana.26750  0.333
2023 Smedley J, Turkbey B, Bernardo ML, Del Prete GQ, Estes JD, Griffiths GL, Kobayashi H, Choyke PL, Lifson JD, Keele BF. Correction: Tracking the Luminal Exposure and Lymphatic Drainage Pathways of Intravaginal and Intrarectal Inocula Used in Nonhuman Primate Models of HIV Transmission. Plos One. 18: e0288566. PMID 37418480 DOI: 10.1371/journal.pone.0288566  0.552
2023 Wu HL, Busman-Sahay K, Weber WC, Waytashek CM, Boyle CD, Bateman KB, Reed JS, Hwang JM, Shriver-Munsch C, Swanson T, Northrup M, Armantrout K, Price H, Robertson-LeVay M, Uttke S, ... ... Estes JD, et al. Allogeneic immunity clears latent virus following allogeneic stem cell transplantation in SIV-infected ART-suppressed macaques. Immunity. PMID 37236188 DOI: 10.1016/j.immuni.2023.04.019  0.437
2023 Samer S, Chowdhury A, Wiche Salinas TR, Estrada PMDR, Reuter M, Tharp G, Bosinger S, Cervasi B, Auger J, Gill K, Ablanedo-Terrazas Y, Reyes-Teran G, Estes JD, Betts MR, Silvestri G, et al. Lymph-Node-Based CD3 CD20 Cells Emerge from Membrane Exchange between T Follicular Helper Cells and B Cells and Increase Their Frequency following Simian Immunodeficiency Virus Infection. Journal of Virology. e0176022. PMID 37223960 DOI: 10.1128/jvi.01760-22  0.533
2023 Bochart RM, Busman-Sahay K, Bondoc S, Morrow DW, Ortiz AM, Fennessey CM, Fischer MB, Shiel O, Swanson T, Shriver-Munsch CM, Crank HB, Armantrout KM, Barber-Axthelm AM, Langner C, Moats CR, ... ... Estes JD, et al. Correction: Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques. Plos Pathogens. 19: e1011343. PMID 37075022 DOI: 10.1371/journal.ppat.1011343  0.48
2023 Byrnes SJ, Busman-Sahay K, Angelovich TA, Younger S, Taylor-Brill S, Nekorchuk M, Bondoc S, Dannay R, Terry M, Cochrane CR, Jenkins TA, Roche M, Deleage C, Bosinger SE, Paiardini M, ... ... Estes JD, et al. Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques. Plos Pathogens. 19: e1011290. PMID 36989320 DOI: 10.1371/journal.ppat.1011290  0.453
2023 Le Hingrat Q, Sette P, Xu C, Rahmberg AR, Tarnus L, Annapureddy H, Kleinman A, Brocca-Cofano E, Sivanandham R, Sivanandham S, He T, Capreri DJ, Ma D, Estes JD, Brenchley JM, et al. Prolonged experimental CD4 T-cell depletion does not cause disease progression in SIV-infected African green monkeys. Nature Communications. 14: 979. PMID 36813761 DOI: 10.1038/s41467-023-36379-2  0.49
2023 Jensen BO, Knops E, Cords L, Lübke N, Salgado M, Busman-Sahay K, Estes JD, Huyveneers LEP, Perdomo-Celis F, Wittner M, Gálvez C, Mummert C, Passaes C, Eberhard JM, Münk C, et al. In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation. Nature Medicine. PMID 36807684 DOI: 10.1038/s41591-023-02213-x  0.452
2022 Hoang TN, Viox EG, Upadhyay AA, Strongin Z, Tharp GK, Pino M, Nchioua R, Hirschenberger M, Gagne M, Nguyen K, Harper JL, Marciano S, Boddapati AK, Pellegrini KL, Tisoncik-Go J, ... ... Estes JD, et al. Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques. Biorxiv : the Preprint Server For Biology. PMID 36324810 DOI: 10.1101/2022.10.21.512606  0.328
2022 Byrnes SJ, Angelovich TA, Busman-Sahay K, Cochrane CR, Roche M, Estes JD, Churchill MJ. Non-Human Primate Models of HIV Brain Infection and Cognitive Disorders. Viruses. 14. PMID 36146803 DOI: 10.3390/v14091997  0.401
2022 Baharlou H, Canete N, Vine EE, Hu K, Yuan D, Sandgren KJ, Bertram KM, Nasr N, Rhodes JW, Gosselink MP, Di Re A, Reza F, Ctercteko G, Pathma-Nathan N, Collins G, ... ... Estes JD, et al. An in situ analysis pipeline for initial host-pathogen interactions reveals signatures of human colorectal HIV transmission. Cell Reports. 40: 111385. PMID 36130503 DOI: 10.1016/j.celrep.2022.111385  0.519
2022 Beura LK, Scott MC, Pierson MJ, Joag V, Wijeyesinghe S, Semler MR, Quarnstrom CF, Busman-Sahay K, Estes JD, Hamilton SE, Vezys V, O'Connor DH, Masopust D. Novel Lymphocytic Choriomeningitis Virus Strain Sustains Abundant Exhausted Progenitor CD8 T Cells without Systemic Viremia. Journal of Immunology (Baltimore, Md. : 1950). PMID 36122933 DOI: 10.4049/jimmunol.2200320  0.401
2022 Cochrane CR, Angelovich TA, Byrnes SJ, Waring E, Guanizo AC, Trollope GS, Zhou J, Vue J, Senior L, Wanicek E, Jamal Eddine J, Gartner MJ, Jenkins TA, Gorry PR, Brew BJ, ... ... Estes JD, et al. Intact HIV proviruses persist in the brain despite viral suppression with ART. Annals of Neurology. PMID 35867351 DOI: 10.1002/ana.26456  0.403
2022 Devanathan AS, White NR, Desyaterik Y, De la Cruz G, Nekorchuk M, Terry M, Busman-Sahay K, Adamson L, Luciw P, Fedoriw Y, Estes JD, Rosen EP, Kashuba ADM. Quantitative Imaging Analysis of the Spatial Relationship between Antiretrovirals, Reverse Transcriptase Simian-Human Immunodeficiency Virus RNA, and Fibrosis in the Spleens of Nonhuman Primates. Antimicrobial Agents and Chemotherapy. e0060922. PMID 35856680 DOI: 10.1128/aac.00609-22  0.353
2022 Jiang S, Chan CN, Rovira-Clavé X, Chen H, Bai Y, Zhu B, McCaffrey E, Greenwald NF, Liu C, Barlow GL, Weirather JL, Oliveria JP, Nakayama T, Lee IT, Matter MS, ... ... Estes JD, et al. Combined protein and nucleic acid imaging reveals virus-dependent B cell and macrophage immunosuppression of tissue microenvironments. Immunity. PMID 35447093 DOI: 10.1016/j.immuni.2022.03.020  0.41
2022 Rosen EP, Deleage C, White N, Sykes C, Brands C, Adamson L, Luciw P, Estes JD, Kashuba ADM. Antiretroviral drug exposure in lymph nodes is heterogeneous and drug dependent. Journal of the International Aids Society. 25: e25895. PMID 35441468 DOI: 10.1002/jia2.25895  0.363
2022 Varco-Merth BD, Brantley W, Marenco A, Duell DD, Fachko DN, Richardson B, Busman-Sahay K, Shao D, Flores W, Engelman K, Fukazawa Y, Wong SW, Skalsky RL, Smedley J, Axthelm MK, ... ... Estes JD, et al. Rapamycin limits CD4+ T cell proliferation in simian immunodeficiency virus-infected rhesus macaques on antiretroviral therapy. The Journal of Clinical Investigation. PMID 35316218 DOI: 10.1172/JCI156063  0.47
2022 Harper J, Ribeiro SP, Chan CN, Aid M, Deleage C, Micci L, Pino M, Cervasi B, Raghunathan G, Rimmer E, Ayanoglu G, Wu G, Shenvi N, Barnard RJ, Del Prete GQ, ... ... Estes JD, et al. Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy. The Journal of Clinical Investigation. PMID 35230978 DOI: 10.1172/JCI155251  0.376
2022 Swainson LA, Sharma AA, Ghneim K, Ribeiro SP, Wilkinson P, Dunham RM, Albright RG, Wong S, Estes JD, Piatak M, Deeks SG, Hunt PW, Sekaly RP, McCune JM. IFNα-blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health. Jci Insight. PMID 35104248 DOI: 10.1172/jci.insight.153046  0.417
2022 Burdick RC, Deleage C, Duchon A, Estes JD, Hu WS, Pathak VK. Intranuclear Positions of HIV-1 Proviruses Are Dynamic and Do Not Correlate with Transcriptional Activity. Mbio. e0325621. PMID 35012348 DOI: 10.1128/mbio.03256-21  0.373
2022 Busman-Sahay K, Nekorchuk MD, Starke CE, Chan CN, Estes JD. In Situ Multiplexing to Identify, Quantify, and Phenotype the HIV-1/SIV Reservoir Within Lymphoid Tissue. Methods in Molecular Biology (Clifton, N.J.). 2407: 277-290. PMID 34985671 DOI: 10.1007/978-1-0716-1871-4_19  0.492
2021 Richardson ZA, Deleage C, Tutuka CSA, Walkiewicz M, Del Río-Estrada PM, Pascoe RD, Evans VA, Reyesteran G, Gonzales M, Roberts-Thomson S, González-Navarro M, Torres-Ruiz F, Estes JD, Lewin SR, Cameron PU. Multiparameter immunohistochemistry analysis of HIV DNA, RNA and immune checkpoints in lymph node tissue. Journal of Immunological Methods. 113198. PMID 34863818 DOI: 10.1016/j.jim.2021.113198  0.492
2021 Buckley S, Byrnes S, Cochrane C, Roche M, Estes JD, Selemidis S, Angelovich TA, Churchill MJ. The role of oxidative stress in HIV-associated neurocognitive disorders. Brain, Behavior, & Immunity - Health. 13: 100235. PMID 34589750 DOI: 10.1016/j.bbih.2021.100235  0.316
2021 Lee MY, Upadhyay AA, Walum H, Chan CN, Dawoud RA, Grech C, Harper JL, Karunakaran KA, Nelson SA, Mahar EA, Goss KL, Carnathan DG, Cervasi B, Gill K, Tharp GK, ... ... Estes JD, et al. Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection. Plos Pathogens. 17: e1009674. PMID 34181694 DOI: 10.1371/journal.ppat.1009674  0.504
2021 Busman-Sahay K, Starke CE, Nekorchuk MD, Estes JD. Eliminating HIV reservoirs for a cure: the issue is in the tissue. Current Opinion in Hiv and Aids. 16: 200-208. PMID 34039843 DOI: 10.1097/COH.0000000000000688  0.464
2021 Bochart RM, Busman-Sahay K, Bondoc S, Morrow DW, Ortiz AM, Fennessey CM, Fischer MB, Shiel O, Swanson T, Shriver-Munsch CM, Crank HB, Armantrout KM, Barber-Axthelm AM, Langner C, Moats CR, ... ... Estes JD, et al. Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques. Plos Pathogens. 17: e1009565. PMID 33970966 DOI: 10.1371/journal.ppat.1009565  0.601
2021 Scholz EMB, Mwangi JN, De la Cruz G, Nekorchuk M, Chan CN, Busman-Sahay K, Adamson L, Luciw P, Fedoriw Y, Estes JD, Rosen EP, Kashuba ADM. Quantitative Imaging Analysis of the Spatial Relationship between Antiretrovirals, RT-SHIV RNA, and Collagen in the Mesenteric Lymph Nodes of Nonhuman Primates. Antimicrobial Agents and Chemotherapy. PMID 33782003 DOI: 10.1128/AAC.00019-21  0.313
2021 Gern BH, Adams KN, Plumlee CR, Stoltzfus CR, Shehata L, Moguche AO, Busman-Sahay K, Hansen SG, Axthelm MK, Picker LJ, Estes JD, Urdahl KB, Gerner MY. TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma. Cell Host & Microbe. PMID 33711270 DOI: 10.1016/j.chom.2021.02.005  0.37
2021 Okoye AA, Duell DD, Fukazawa Y, Varco-Merth B, Marenco A, Behrens H, Chaunzwa TM, Selseth AN, Gilbride RM, Shao J, Edlefsen PT, Geleziunas R, Pinkevych M, Davenport MP, Busman-Sahay K, ... ... Estes JD, et al. CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification. The Journal of Clinical Investigation. PMID 33630764 DOI: 10.1172/JCI141677  0.643
2021 Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, ... ... Estes JD, et al. Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity . Journal of Virology. PMID 33536176 DOI: 10.1128/JVI.02393-20  0.431
2021 Uruena A, Cassetti I, Kashyap N, Deleage C, Estes JD, Trindade C, Hammoud DA, Burbelo PD, Natarajan V, Dewar R, Imamichi H, Ward AJ, Poole A, Ober A, Rehm C, et al. Prolonged Posttreatment Virologic Control and Complete Seroreversion After Advanced Human Immunodeficiency Virus-1 Infection. Open Forum Infectious Diseases. 8: ofaa613. PMID 33511235 DOI: 10.1093/ofid/ofaa613  0.46
2021 Swanstrom AE, Immonen TT, Oswald K, Pyle C, Thomas JA, Bosche WJ, Silipino L, Hull M, Newman L, Coalter V, Wiles A, Wiles R, Kiser J, Morcock DR, Shoemaker R, ... ... Estes JD, et al. Antibody-mediated depletion of viral reservoirs is limited in SIV-infected macaques treated early with antiretroviral therapy. The Journal of Clinical Investigation. PMID 33465055 DOI: 10.1172/JCI142421  0.684
2020 Taher H, Mahyari E, Kreklywich C, Uebelhoer LS, McArdle MR, Moström MJ, Bhusari A, Nekorchuk M, E X, Whitmer T, Scheef EA, Sprehe LM, Roberts DL, Hughes CM, Jackson KA, ... ... Estes JD, et al. In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome. Plos Pathogens. 16: e1008666. PMID 33232376 DOI: 10.1371/journal.ppat.1008666  0.339
2020 Hoang TN, Pino M, Boddapati AK, Viox EG, Starke CE, Upadhyay AA, Gumber S, Busman-Sahay K, Strongin Z, Harper JL, Tharp GK, Pellegrini KL, Kirejczyk S, Zandi K, Tao S, ... ... Estes JD, et al. Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques. Biorxiv : the Preprint Server For Biology. PMID 32995780 DOI: 10.1101/2020.09.16.300277  0.311
2020 Singh KP, Zerbato JM, Zhao W, Braat S, Deleage C, Tennakoon GS, Mason H, Dantanarayana A, Rhodes A, Rhodes JW, Torresi J, Harman AN, Revill PA, Crane M, Estes JD, et al. Intrahepatic CXCL10 is strongly associated with liver fibrosis in HIV-Hepatitis B co-infection. Plos Pathogens. 16: e1008744. PMID 32898182 DOI: 10.1371/Journal.Ppat.1008744  0.534
2020 Abdel-Mohsen M, Richman D, Siliciano RF, Nussenzweig MC, Howell BJ, Martinez-Picado J, Chomont N, Bar KJ, Yu XG, Lichterfeld M, Alcami J, Hazuda D, Bushman F, Siliciano JD, Betts MR, ... ... Estes JD, et al. Recommendations for measuring HIV reservoir size in cure-directed clinical trials. Nature Medicine. PMID 32895573 DOI: 10.1038/S41591-020-1022-1  0.412
2020 Tostanoski LH, Wegmann F, Martinot AJ, Loos C, McMahan K, Mercado NB, Yu J, Chan CN, Bondoc S, Starke CE, Nekorchuk M, Busman-Sahay K, Piedra-Mora C, Wrijil LM, Ducat S, ... ... Estes JD, et al. Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters. Nature Medicine. PMID 32884153 DOI: 10.1038/S41591-020-1070-6  0.336
2020 Om K, Paquin-Proulx D, Montero M, Peachman K, Shen X, Wieczorek L, Beck Z, Weiner JA, Kim D, Li Y, Mdluli T, Shubin Z, Bryant C, Sharma V, Tokarev A, ... ... Estes JD, et al. Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge. Plos Pathogens. 16: e1008764. PMID 32881968 DOI: 10.1371/Journal.Ppat.1008764  0.379
2020 Stevens DM, Adiseshaiah P, Dasa SSK, Potter TM, Skoczen SL, Snapp KS, Cedrone E, Patel N, Busman-Sahay K, Rosen EP, Sykes C, Cottrell M, Dobrovolskaia MA, Estes JD, Kashuba ADM, et al. Application of a Scavenger Receptor A1 Targeted Polymeric Prodrug Platform for Lymphatic Drug Delivery in HIV. Molecular Pharmaceutics. PMID 32841040 DOI: 10.1021/Acs.Molpharmaceut.0C00562  0.333
2020 Chandrashekar A, Liu J, Martinot AJ, McMahan K, Mercado NB, Peter L, Tostanoski LH, Yu J, Maliga Z, Nekorchuk M, Busman-Sahay K, Terry M, Wrijil LM, Ducat S, Martinez DR, ... ... Estes JD, et al. SARS-CoV-2 infection protects against rechallenge in rhesus macaques. Science (New York, N.Y.). PMID 32434946 DOI: 10.1126/Science.Abc4776  0.456
2020 Harper J, Gordon S, Chan CN, Wang H, Lindemuth E, Galardi C, Falcinelli SD, Raines SLM, Read JL, Nguyen K, McGary CS, Nekorchuk M, Busman-Sahay K, Schawalder J, King C, ... ... Estes JD, et al. CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption. Nature Medicine. 26: 519-528. PMID 32284611 DOI: 10.1038/S41591-020-0782-Y  0.487
2020 Mavigner M, Habib J, Deleage C, Rosen E, Mattingly C, Bricker K, Kashuba A, Amblard F, Schinazi RF, Lawson B, Vanderford TH, Jean S, Cohen J, McGary C, Paiardini M, ... ... Estes J, et al. Correction for Mavigner et al., "Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques". Journal of Virology. 94. PMID 32234801 DOI: 10.1128/Jvi.01742-19  0.303
2020 Webb GM, Molden J, Busman-Sahay K, Abdulhaqq S, Wu HL, Weber WC, Bateman KB, Reed JS, Northrup M, Maier N, Tanaka S, Gao L, Davey B, Carpenter BL, Axthelm MK, ... ... Estes JD, et al. The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques. Plos Pathogens. 16: e1008339. PMID 32163523 DOI: 10.1371/Journal.Ppat.1008339  0.581
2020 Raehtz KD, Barrenäs F, Xu C, Busman-Sahay K, Valentine A, Law L, Ma D, Policicchio BB, Wijewardana V, Brocca-Cofano E, Trichel A, Gale M, Keele BF, Estes JD, Apetrei C, et al. African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity. Plos Pathogens. 16: e1008333. PMID 32119719 DOI: 10.1371/Journal.Ppat.1008333  0.702
2020 Wang Y, Lifshitz L, Gellatly K, Vinton CL, Busman-Sahay K, McCauley S, Vangala P, Kim K, Derr A, Jaiswal S, Kucukural A, McDonel P, Hunt PW, Greenough T, Houghton J, ... ... Estes JD, et al. HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells. Nature Immunology. PMID 32066947 DOI: 10.1038/S41590-020-0593-9  0.484
2020 McBrien JB, Mavigner M, Franchitti L, Smith SA, White E, Tharp GK, Walum H, Busman-Sahay K, Aguilera-Sandoval CR, Thayer WO, Spagnuolo RA, Kovarova M, Wahl A, Cervasi B, Margolis DM, ... ... Estes JD, et al. Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8 cells. Nature. PMID 32015546 DOI: 10.1038/S41586-020-2002-9  0.486
2020 McBrien JB, Mavigner M, Franchitti L, Smith SA, White E, Tharp GK, Walum H, Busman-Suhay K, Aguilera-Sandoval CR, Thayer WO, Spagnuolo RA, Kovarova M, Wahl A, Cervasi B, Margolis DM, ... ... Estes JD, et al. Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8 cells. Nature. PMID 31969705 DOI: 10.1038/S41586-020-1946-0  0.632
2019 Nguyen S, Deleage C, Darko S, Ransier A, Truong DP, Agarwal D, Japp AS, Wu VH, Kuri-Cervantes L, Abdel-Mohsen M, Del Rio Estrada PM, Ablanedo-Terrazas Y, Gostick E, Hoxie JA, Zhang NR, ... ... Estes JD, et al. Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8 T cells. Science Translational Medicine. 11. PMID 31852798 DOI: 10.1126/Scitranslmed.Aax4077  0.592
2019 Pino M, Paganini S, Deleage C, Padhan K, Harper JL, King CT, Micci L, Cervasi B, Mudd JC, Gill KP, Jean SM, Easley K, Silvestri G, Estes JD, Petrovas C, et al. Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence. Plos Pathogens. 15: e1008081. PMID 31626660 DOI: 10.1371/Journal.Ppat.1008081  0.585
2019 McQueen P, Busman-Sahay K, Rieder F, Noël-Romas L, McCorrister S, Westmacott G, Estes JD, Burgener A. Intestinal proteomic analysis of a novel non-human primate model of experimental colitis reveals signatures of mitochondrial and metabolic dysfunction. Mucosal Immunology. PMID 31481749 DOI: 10.1038/S41385-019-0200-2  0.436
2019 Schleimann MH, Kobberø ML, Vibholm LK, Kjær K, Giron LB, Busman-Sahay K, Chan CN, Nekorchuk M, Schmidt M, Wittig B, Damsgaard TE, Ahlburg P, Hellfritzsch MB, Zuwala K, Rothemejer FH, ... ... Estes JD, et al. TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodes. Ebiomedicine. PMID 31300344 DOI: 10.1016/J.Ebiom.2019.07.005  0.342
2019 Swainson LA, Ahn H, Pajanirassa P, Khetarpal V, Deleage C, Estes JD, Hunt PW, Munoz-Sanjuan I, McCune JM. Kynurenine 3-Monooxygenase Inhibition during Acute Simian Immunodeficiency Virus Infection Lowers PD-1 Expression and Improves Post-Combination Antiretroviral Therapy CD4 T Cell Counts and Body Weight. Journal of Immunology (Baltimore, Md. : 1950). PMID 31285277 DOI: 10.4049/Jimmunol.1801649  0.579
2019 Thompson CG, Rosen EP, Prince HMA, White N, Sykes C, de la Cruz G, Mathews M, Deleage C, Estes JD, Charlins P, Mulder LR, Kovarova M, Adamson L, Arora S, Dellon ES, et al. Heterogeneous antiretroviral drug distribution and HIV/SHIV detection in the gut of three species. Science Translational Medicine. 11. PMID 31270274 DOI: 10.1126/Scitranslmed.Aap8758  0.498
2019 Bertram KM, Botting RA, Baharlou H, Rhodes JW, Rana H, Graham JD, Patrick E, Fletcher J, Plasto TM, Truong NR, Royle C, Doyle CM, Tong O, Nasr N, Barnouti L, ... ... Estes JD, et al. Identification of HIV transmitting CD11c human epidermal dendritic cells. Nature Communications. 10: 2759. PMID 31227717 DOI: 10.1038/S41467-019-10697-W  0.56
2019 Peterson CW, Adair JE, Wohlfahrt ME, Deleage C, Radtke S, Rust B, Norman KK, Norgaard ZK, Schefter LE, Sghia-Hughes GM, Repetto A, Baldessari A, Murnane RD, Estes JD, Kiem HP. Autologous, Gene-Modified Hematopoietic Stem and Progenitor Cells Repopulate the Central Nervous System with Distinct Clonal Variants. Stem Cell Reports. PMID 31204301 DOI: 10.1016/J.Stemcr.2019.05.016  0.386
2019 Del Prete GQ, Alvord WG, Li Y, Deleage C, Nag M, Oswald K, Thomas JA, Pyle C, Bosche WJ, Coalter V, Wiles A, Wiles R, Berkemeier B, Hull M, Chipriano E, ... ... Estes JD, et al. TLR7 agonist administration to SIV-infected macaques receiving early initiated cART does not induce plasma viremia. Jci Insight. 4. PMID 31167974 DOI: 10.1172/Jci.Insight.127717  0.583
2019 Deleage C, Immonen TT, Fennessey CM, Reynaldi A, Reid C, Newman L, Lipkey L, Schlub TE, Camus C, O'Brien S, Smedley J, Conway JM, Del Prete GQ, Davenport MP, Lifson JD, ... Estes JD, et al. Defining early SIV replication and dissemination dynamics following vaginal transmission. Science Advances. 5: eaav7116. PMID 31149634 DOI: 10.1126/Sciadv.Aav7116  0.673
2019 Jiang G, Maverakis E, Cheng MY, Elsheikh MM, Deleage C, Méndez-Lagares G, Shimoda M, Yukl SA, Hartigan-O'Connor DJ, Thompson GR, Estes JD, Wong JK, Dandekar S. Disruption of latent HIV in vivo during the clearance of actinic keratosis by ingenol mebutate. Jci Insight. 4. PMID 30944245 DOI: 10.1172/Jci.Insight.126027  0.527
2019 Mavigner M, Habib J, Deleage C, Rosen E, Mattingly C, Bricker K, Kashuba A, Amblard F, Schinazi RF, Lawson B, Vanderford TH, Jean S, Cohen J, McGary C, Paiardini M, ... ... Estes J, et al. Correction for Mavigner et al., "Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques". Journal of Virology. 93. PMID 30655382 DOI: 10.1128/Jvi.01814-18  0.324
2018 Mudd JC, Busman-Sahay K, DiNapoli SR, Lai S, Sheik V, Lisco A, Deleage C, Richardson B, Palesch DJ, Paiardini M, Cameron M, Sereti I, Reeves RK, Estes JD, Brenchley JM. Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells. Nature Communications. 9: 3967. PMID 30262807 DOI: 10.1038/S41467-018-05528-3  0.631
2018 Mylvaganam GH, Chea LS, Tharp GK, Hicks S, Velu V, Iyer SS, Deleage C, Estes JD, Bosinger SE, Freeman GJ, Ahmed R, Amara RR. Combination anti-PD-1 and antiretroviral therapy provides therapeutic benefit against SIV. Jci Insight. 3. PMID 30232277 DOI: 10.1172/Jci.Insight.122940  0.487
2018 Ortiz AM, Flynn JK, DiNapoli SR, Vujkovic-Cvijin I, Starke CE, Lai SH, Long ME, Sortino O, Vinton CL, Mudd JC, Johnston L, Busman-Sahay K, Belkaid Y, Estes JD, Brenchley JM. Experimental microbial dysbiosis does not promote disease progression in SIV-infected macaques. Nature Medicine. PMID 30061696 DOI: 10.1038/S41591-018-0132-5  0.51
2018 Marshall VA, Labo N, Hao XP, Holdridge B, Thompson M, Miley W, Brands C, Coalter V, Kiser R, Anver M, Golubeva Y, Warner A, Jaffe ES, Piatak M, Wong SW, ... ... Estes JD, et al. Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV. Plos Pathogens. 14: e1007130. PMID 30001436 DOI: 10.1371/Journal.Ppat.1007130  0.513
2018 Mavigner M, Habib J, Deleage C, Rosen E, Mattingly C, Bricker K, Kashuba A, Amblard F, Schinazi RF, Jean S, Cohen J, McGary C, Paiardini M, Wood MP, Sodora DL, ... ... Estes J, et al. SIV persistence in cellular and anatomic reservoirs in ART-suppressed infant rhesus macaques. Journal of Virology. PMID 29997216 DOI: 10.1128/Jvi.00562-18  0.513
2018 Aid M, Dupuy FP, Moysi E, Moir S, Haddad EK, Estes JD, Sekaly RP, Petrovas C, Ribeiro SP. Follicular CD4 T Helper Cells As a Major HIV Reservoir Compartment: A Molecular Perspective. Frontiers in Immunology. 9: 895. PMID 29967602 DOI: 10.3389/Fimmu.2018.00895  0.563
2018 Hensley-McBain T, Berard AR, Manuzak JA, Miller CJ, Zevin AS, Polacino P, Gile J, Agricola B, Cameron M, Hu SL, Estes JD, Reeves RK, Smedley J, Keele BF, Burgener AD, et al. Intestinal damage precedes mucosal immune dysfunction in SIV infection. Mucosal Immunology. PMID 29907866 DOI: 10.1038/S41385-018-0032-5  0.614
2018 Rothenberger M, Wagner JE, Haase A, Richman D, Grzywacz B, Strain M, Lada S, Estes J, Fletcher CV, Podany AT, Anderson J, Schmidt T, Wietgrefe S, Schacker T, Verneris MR. Transplantation of CCR5∆32 Homozygous Umbilical Cord Blood in a Child With Acute Lymphoblastic Leukemia and Perinatally Acquired HIV Infection. Open Forum Infectious Diseases. 5: ofy090. PMID 29868623 DOI: 10.1093/Ofid/Ofy090  0.47
2018 Peterson CW, Wang J, Deleage C, Reddy S, Kaur J, Polacino P, Reik A, Huang ML, Jerome KR, Hu SL, Holmes MC, Estes JD, Kiem HP. Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy. Plos Pathogens. 14: e1006956. PMID 29672640 DOI: 10.1371/Journal.Ppat.1006956  0.542
2018 Hsu DC, Sunyakumthorn P, Wegner M, Schuetz A, Silsorn D, Estes JD, Deleage C, Tomusange K, Lakhashe SK, Ruprecht RM, Lombardini E, Im-Erbsin R, Kuncharin Y, Phuang-Ngern Y, Inthawong D, et al. Central Nervous System Inflammation and Infection During Early, Non-Accelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques. Journal of Virology. PMID 29563297 DOI: 10.1128/Jvi.00222-18  0.627
2018 Estes JD, Wong SW, Brenchley JM. Nonhuman primate models of human viral infections. Nature Reviews. Immunology. PMID 29556017 DOI: 10.1038/S41577-018-0005-7  0.49
2018 Estes JD, LeGrand R, Petrovas C. Visualizing the Immune System: Providing Key Insights into HIV/SIV Infections. Frontiers in Immunology. 9: 423. PMID 29552017 DOI: 10.3389/Fimmu.2018.00423  0.449
2018 Watson DC, Moysi E, Valentin A, Bergamaschi C, Devasundaram S, Fortis SP, Bear J, Chertova E, Bess J, Sowder R, Venzon DJ, Deleage C, Estes JD, Lifson JD, Petrovas C, et al. Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes. Plos Pathogens. 14: e1006902. PMID 29474450 DOI: 10.1371/Journal.Ppat.1006902  0.552
2018 Utay NS, Kitch DW, Yeh E, Fichtenbaum CJ, Lederman MM, Estes JD, Deleage C, Magyar C, Nelson SD, Klingman KL, Bastow B, Luque AE, McComsey GA, Douek DC, Currier JS, et al. Telmisartan Does Not Improve Lymph Node or Adipose Tissue Fibrosis More Than Continued ART Alone. The Journal of Infectious Diseases. PMID 29401318 DOI: 10.1093/Infdis/Jiy064  0.365
2018 Deleage C, Chan CN, Busman-Sahay K, Estes JD. Next-generation in situ hybridization approaches to define and quantify HIV and SIV reservoirs in tissue microenvironments. Retrovirology. 15: 4. PMID 29316956 DOI: 10.1186/S12977-017-0387-9  0.508
2018 Rieder F, Busman-Sahay K, Patil DT, Mao R, Kurada S, Estes JD. Tu1831 - A Novel Model of Intestinal Fibrosis in Non-Human Primates is Independent of Cd4+ Cells Gastroenterology. 154: S-1031-S-1032. DOI: 10.1016/S0016-5085(18)33457-7  0.357
2017 McGary CS, Deleage C, Harper J, Micci L, Ribeiro SP, Paganini S, Kuri-Cervantes L, Benne C, Ryan ES, Balderas R, Jean S, Easley K, Marconi V, Silvestri G, Estes JD, et al. CTLA-4(+)PD-1(-) Memory CD4(+) T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques. Immunity. 47: 776-788.e5. PMID 29045906 DOI: 10.1016/J.Immuni.2017.09.018  0.552
2017 Estes JD, Kityo C, Ssali F, Swainson L, Makamdop KN, Del Prete GQ, Deeks SG, Luciw PA, Chipman JG, Beilman GJ, Hoskuldsson T, Khoruts A, Anderson J, Deleage C, Jasurda J, et al. Defining total-body AIDS-virus burden with implications for curative strategies. Nature Medicine. PMID 28967921 DOI: 10.1038/Nm.4411  0.587
2017 Del Prete GQ, Keele BF, Fode J, Thumar K, Swanstrom AE, Rodriguez A, Raymond A, Estes JD, LaBranche CC, Montefiori DC, KewalRamani VN, Lifson JD, Bieniasz PD, Hatziioannou T. A single gp120 residue can affect HIV-1 tropism in macaques. Plos Pathogens. 13: e1006572. PMID 28945790 DOI: 10.1371/Journal.Ppat.1006572  0.685
2017 Cockerham LR, Yukl SA, Harvill K, Somsouk M, Joshi SK, Sinclair E, Liegler T, Hoh R, Lyons S, Hunt PW, Rupert A, Sereti I, Morcock DR, Rhodes A, Emson C, ... ... Estes JD, et al. A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals. Pathogens & Immunity. 2: 310-334. PMID 28936485 DOI: 10.20411/pai.v2i3.207  0.423
2017 Hansen SG, Piatak M, Ventura AB, Hughes CM, Gilbride RM, Ford JC, Oswald K, Shoemaker R, Li Y, Lewis MS, Gilliam AN, Xu G, Whizin N, Burwitz BJ, Planer SL, ... ... Estes JD, et al. Addendum: Immune clearance of highly pathogenic SIV infection. Nature. PMID 28636599 DOI: 10.1038/Nature22984  0.614
2017 Fennessey CM, Pinkevych M, Immonen TT, Reynaldi A, Venturi V, Nadella P, Reid C, Newman L, Lipkey L, Oswald K, Bosche WJ, Trivett MT, Ohlen C, Ott DE, Estes JD, et al. Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy. Plos Pathogens. 13: e1006359. PMID 28472156 DOI: 10.1371/Journal.Ppat.1006359  0.691
2017 Vinton CL, Ortiz AM, Calantone N, Mudd JC, Deleage C, Morcock DR, Whitted S, Estes JD, Hirsch VM, Brenchley JM. Cytotoxic T Cell Functions Accumulate When CD4 Is Downregulated by CD4(+) T Cells in African Green Monkeys. Journal of Immunology (Baltimore, Md. : 1950). PMID 28438898 DOI: 10.4049/Jimmunol.1700136  0.454
2017 Ayala VI, Deleage C, Trivett MT, Jain S, Coren LV, Breed MW, Kramer JA, Thomas JA, Estes JD, Lifson JD, Ott DE. CXCR5 Dependent Entry of CD8 T Cells into Rhesus Macaque B-Cell Follicles Achieved Through T-Cell Engineering. Journal of Virology. PMID 28298605 DOI: 10.1128/Jvi.02507-16  0.497
2017 Petrovas C, Ferrando-Martinez S, Gerner MY, Casazza JP, Pegu A, Deleage C, Cooper A, Hataye J, Andrews S, Ambrozak D, Del Río Estrada PM, Boritz E, Paris R, Moysi E, Boswell KL, ... ... Estes JD, et al. Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies. Science Translational Medicine. 9. PMID 28100833 DOI: 10.1126/Scitranslmed.Aag2285  0.642
2016 Ericsen AJ, Lauck M, Mohns MS, DiNapoli SR, Mutschler JP, Greene JM, Weinfurter JT, Lehrer-Brey G, Prall TM, Gieger SM, Buechler CR, Crosno KA, Peterson EJ, Reynolds MR, Wiseman RW, ... ... Estes JD, et al. Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication. Plos Pathogens. 12: e1006048. PMID 27926931 DOI: 10.1371/Journal.Ppat.1006048  0.57
2016 Osuna CE, Lim SY, Deleage C, Griffin BD, Stein D, Schroeder LT, Omage R, Best K, Luo M, Hraber PT, Andersen-Elyard H, Ojeda EF, Huang S, Vanlandingham DL, Higgs S, ... ... Estes JD, et al. Zika viral dynamics and shedding in rhesus and cynomolgus macaques. Nature Medicine. PMID 27694931 DOI: 10.1038/Nm.4206  0.484
2016 Jensen K, Dela Pena-Ponce MG, Piatak M, Shoemaker R, Oswald K, Jacobs WR, Fennelly G, Lucero C, Mollan KR, Hudgens MG, Amedee A, Kozlowski PA, Estes JD, Lifson JD, Van Rompay KK, et al. Balancing trained immunity with persistent immune activation and the risk of SIV infection in infant macaques vaccinated with attenuated Mycobacterium tuberculosis or BCG vaccines. Clinical and Vaccine Immunology : Cvi. PMID 27655885 DOI: 10.1128/Cvi.00360-16  0.35
2016 Cartwright EK, Spicer L, Smith SA, Lee D, Fast R, Paganini S, Lawson BO, Nega M, Easley K, Schmitz JE, Bosinger SE, Paiardini M, Chahroudi A, Vanderford TH, Estes JD, et al. CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy. Immunity. 45: 656-68. PMID 27653601 DOI: 10.1016/J.Immuni.2016.08.018  0.6
2016 Deleage C, Turkbey B, Estes JD. Imaging lymphoid tissues in nonhuman primates to understand SIV pathogenesis and persistence. Current Opinion in Virology. 19: 77-84. PMID 27490446 DOI: 10.1016/J.Coviro.2016.07.002  0.607
2016 Leong YA, Chen Y, Ong HS, Wu D, Man K, Deleage C, Minnich M, Meckiff BJ, Wei Y, Hou Z, Zotos D, Fenix KA, Atnerkar A, Preston S, Chipman JG, ... ... Estes JD, et al. CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles. Nature Immunology. PMID 27487330 DOI: 10.1038/Ni.3543  0.484
2016 Deleage C, Schuetz A, Alvord WG, Johnston L, Hao XP, Morcock DR, Rerknimitr R, Fletcher JL, Puttamaswin S, Phanuphak N, Dewar R, McCune JM, Sereti I, Robb M, Kim JH, ... ... Estes JD, et al. Impact of early cART in the gut during acute HIV infection. Jci Insight. 1. PMID 27446990 DOI: 10.1172/Jci.Insight.87065  0.61
2016 DeGottardi MQ, Okoye AA, Vaidya M, Talla A, Konfe AL, Reyes MD, Clock JA, Duell DM, Legasse AW, Sabnis A, Park BS, Axthelm MK, Estes JD, Reiman KA, Sekaly RP, et al. Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques. Journal of Immunology (Baltimore, Md. : 1950). PMID 27430715 DOI: 10.4049/Jimmunol.1600065  0.311
2016 Deleage C, Wietgrefe SW, Del Prete G, Morcock DR, Hao XP, Piatak M, Bess J, Anderson JL, Perkey KE, Reilly C, McCune JM, Haase AT, Lifson JD, Schacker TW, Estes JD. Defining HIV and SIV Reservoirs in Lymphoid Tissues. Pathogens & Immunity. 1: 68-106. PMID 27430032  0.455
2016 Lopker MJ, Del Prete GQ, Estes JD, Li H, Reid C, Newman L, Lipkey L, Camus C, Easlick JL, Wang S, Decker JM, Bar KJ, Learn G, Pal R, Weiss DE, et al. Derivation and characterization of pathogenic transmitted/founder molecular clones from SIVsmE660 and SIVmac251 following mucosal infection. Journal of Virology. PMID 27412591 DOI: 10.1128/Jvi.00718-16  0.666
2016 Younes SA, Freeman ML, Mudd JC, Shive CL, Reynaldi A, Panigrahi S, Estes JD, Deleage C, Lucero C, Anderson J, Schacker TW, Davenport MP, McCune JM, Hunt PW, Lee SA, et al. IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection. The Journal of Clinical Investigation. PMID 27322062 DOI: 10.1172/Jci85996  0.586
2016 Li H, Wang S, Kong R, Ding W, Lee FH, Parker Z, Kim E, Learn GH, Hahn P, Policicchio B, Brocca-Cofano E, Deleage C, Hao X, Chuang GY, Gorman J, ... ... Estes JD, et al. Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America. PMID 27247400 DOI: 10.1073/Pnas.1606636113  0.71
2016 Utay NS, Roque A, Timmer JK, Morcock DR, DeLeage C, Somasunderam A, Weintrob AC, Agan BK, Estes JD, Crum-Cianflone NF, Douek DC. MRSA Infections in HIV-Infected People Are Associated with Decreased MRSA-Specific Th1 Immunity. Plos Pathogens. 12: e1005580. PMID 27093273 DOI: 10.1371/Journal.Ppat.1005580  0.616
2016 Moysi E, Estes JD, Petrovas C. Novel Imaging Methods for Analysis of Tissue Resident Cells in HIV/SIV. Current Hiv/Aids Reports. 13: 38-43. PMID 26830285 DOI: 10.1007/S11904-016-0300-5  0.384
2016 Manuzak JA, Hensley-McBain T, Zevin AS, Miller C, Cubas R, Agricola B, Gile J, Richert-Spuhler L, Patilea G, Estes JD, Langevin S, Reeves RK, Haddad EK, Klatt NR. Enhancement of Microbiota in Healthy Macaques Results in Beneficial Modulation of Mucosal and Systemic Immune Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 26826246 DOI: 10.4049/Jimmunol.1502470  0.419
2016 Mavigner M, Deleage C, Habib J, Rosen E, Kashuba A, Amblard F, Schinazi R, Geleziunas R, Hesselgesser J, Li B, Hattersley J, Mcgary C, Paiardini M, Wood M, Sodora D, ... ... Estes J, et al. Simian Immunodeficiency Virus (SIV) Persistence in Antiretroviral Therapy (ART)-Treated Infant Rhesus Macaques Open Forum Infectious Diseases. 3. DOI: 10.1093/Ofid/Ofw172.09  0.37
2015 Del Prete GQ, Oswald K, Lara A, Shoemaker R, Smedley J, Macallister R, Coalter V, Wiles A, Wiles R, Li Y, Fast R, Kiser R, Lu B, Zheng J, Alvord WG, ... ... Estes JD, et al. Elevated plasma viral loads in romidepsin treated SIV-infected rhesus macaques on suppressive combination antiretroviral therapy. Antimicrobial Agents and Chemotherapy. PMID 26711758 DOI: 10.1128/Aac.02625-15  0.702
2015 Sheikh V, Porter BO, DerSimonian R, Kovacs SB, Thompson WL, Perez-Diez A, Freeman AF, Roby G, Mican J, Pau A, Rupert A, Adelsberger J, Higgins J, Bourgeois JS, Jensen SM, ... ... Estes JD, et al. Administration of interleukin-7 increases CD4 T cells in idiopathic CD4 lymphocytopenia. Blood. PMID 26675348 DOI: 10.1182/Blood-2015-05-645077  0.466
2015 Micci L, Ryan ES, Fromentin R, Bosinger SE, Harper JL, He T, Paganini S, Easley KA, Chahroudi A, Benne C, Gumber S, McGary CS, Rogers KA, Deleage C, Lucero C, ... ... Estes JD, et al. Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques. The Journal of Clinical Investigation. PMID 26551680 DOI: 10.1172/Jci81400  0.559
2015 Ortiz AM, Klase ZA, DiNapoli SR, Vujkovic-Cvijin I, Carmack K, Perkins MR, Calantone N, Vinton CL, Riddick NE, Gallagher J, Klatt NR, McCune JM, Estes JD, Paiardini M, Brenchley JM. IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation, and microbiome in ARV-treated, SIV-infected macaques. Mucosal Immunology. PMID 26286233 DOI: 10.1038/Mi.2015.75  0.59
2015 Hao XP, Lucero CM, Turkbey B, Bernardo ML, Morcock DR, Deleage C, Trubey CM, Smedley J, Klatt NR, Giavedoni LD, Kristoff J, Xu A, Del Prete GQ, Keele BF, Rao SS, ... ... Estes JD, et al. Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection. Nature Communications. 6: 8020. PMID 26282376 DOI: 10.1038/Ncomms9020  0.679
2015 Evans TI, Li H, Schafer JL, Klatt NR, Hao XP, Traslavina RP, Estes JD, Brenchley JM, Reeves RK. SIV-induced Translocation of Bacterial Products in the Liver Mobilizes Myeloid Dendritic and Natural Killer Cells Associated With Liver Damage. The Journal of Infectious Diseases. PMID 26238685 DOI: 10.1093/Infdis/Jiv404  0.352
2015 Fennessey CM, Reid C, Lipkey L, Newman L, Oswald K, Piatak M, Roser JD, Chertova E, Smedley J, Gregory Alvord W, Del Prete GQ, Estes JD, Lifson JD, Keele BF. Generation and characterization of a SIVmac239 clone corrected at four suboptimal nucleotides. Retrovirology. 12: 49. PMID 26076651 DOI: 10.1186/S12977-015-0175-3  0.624
2015 Chowdhury A, Hayes TL, Bosinger SE, Lawson BO, Vanderford T, Schmitz JE, Paiardini M, Betts M, Chahroudi A, Estes JD, Silvestri G. Differential impact of in vivo CD8+ T-lymphocyte depletion in controller versus progressor SIV-infected macaques. Journal of Virology. PMID 26063417 DOI: 10.1128/Jvi.00869-15  0.489
2015 Kovacs SB, Sheikh V, Thompson WL, Morcock DR, Perez-Diez A, Yao MD, Rupert AW, Utay NS, Roby G, Freeman AF, Estes JD, Sereti I. T-Cell Depletion in the Colonic Mucosa of Patients With Idiopathic CD4+ Lymphopenia. The Journal of Infectious Diseases. PMID 25995198 DOI: 10.1093/Infdis/Jiv282  0.467
2015 Schafer JL, Li H, Evans TI, Estes JD, Reeves RK. Accumulation of Cytotoxic CD16+ NK Cells in Simian Immunodeficiency Virus-Infected Lymph Nodes Associated with In Situ Differentiation and Functional Anergy. Journal of Virology. 89: 6887-94. PMID 25903330 DOI: 10.1128/Jvi.00660-15  0.538
2015 Rothenberger MK, Keele BF, Wietgrefe SW, Fletcher CV, Beilman GJ, Chipman JG, Khoruts A, Estes JD, Anderson J, Callisto SP, Schmidt TE, Thorkelson A, Reilly C, Perkey K, Reimann TG, et al. Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption. Proceedings of the National Academy of Sciences of the United States of America. 112: E1126-34. PMID 25713386 DOI: 10.1073/Pnas.1414926112  0.734
2015 Fukazawa Y, Lum R, Okoye AA, Park H, Matsuda K, Bae JY, Hagen SI, Shoemaker R, Deleage C, Lucero C, Morcock D, Swanson T, Legasse AW, Axthelm MK, Hesselgesser J, ... ... Estes JD, et al. B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers. Nature Medicine. 21: 132-9. PMID 25599132 DOI: 10.1038/Nm.3781  0.617
2015 Klase Z, Ortiz A, Deleage C, Mudd JC, Quiñones M, Schwartzman E, Klatt NR, Canary L, Estes JD, Brenchley JM. Dysbiotic bacteria translocate in progressive SIV infection. Mucosal Immunology. 8: 1009-20. PMID 25586559 DOI: 10.1038/Mi.2014.128  0.58
2015 Somsouk M, Estes JD, Deleage C, Dunham RM, Albright R, Inadomi JM, Martin JN, Deeks SG, McCune JM, Hunt PW. Gut epithelial barrier and systemic inflammation during chronic HIV infection. Aids (London, England). 29: 43-51. PMID 25387317 DOI: 10.1097/Qad.0000000000000511  0.612
2015 Estes JD, Reilly C, Trubey CM, Fletcher CV, Cory TJ, Piatak M, Russ S, Anderson J, Reimann TG, Star R, Smith A, Tracy RP, Berglund A, Schmidt T, Coalter V, et al. Antifibrotic therapy in simian immunodeficiency virus infection preserves CD4+ T-cell populations and improves immune reconstitution with antiretroviral therapy. The Journal of Infectious Diseases. 211: 744-54. PMID 25246534 DOI: 10.1093/Infdis/Jiu519  0.527
2015 Hao XP, Lucero CM, Turkbey B, Bernardo ML, Morcock DR, Deleage C, Trubey CM, Smedley J, Klatt NR, Giavedoni LD, Kristoff J, Xu A, Del Prete GQ, Keele BF, Rao SS, ... ... Estes JD, et al. Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection Nature Communications. 6. DOI: 10.1038/ncomms9020  0.588
2014 Li H, Richert-Spuhler LE, Evans TI, Gillis J, Connole M, Estes JD, Keele BF, Klatt NR, Reeves RK. Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection. Plos Pathogens. 10: e1004551. PMID 25503264 DOI: 10.1371/Journal.Ppat.1004551  0.661
2014 Schuetz A, Deleage C, Sereti I, Rerknimitr R, Phanuphak N, Phuang-Ngern Y, Estes JD, Sandler NG, Sukhumvittaya S, Marovich M, Jongrakthaitae S, Akapirat S, Fletscher JL, Kroon E, Dewar R, et al. Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation. Plos Pathogens. 10: e1004543. PMID 25503054 DOI: 10.1371/Journal.Ppat.1004543  0.579
2014 Micci L, Alvarez X, Iriele RI, Ortiz AM, Ryan ES, McGary CS, Deleage C, McAtee BB, He T, Apetrei C, Easley K, Pahwa S, Collman RG, Derdeyn CA, Davenport MP, ... Estes JD, et al. CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells. Plos Pathogens. 10: e1004467. PMID 25356757 DOI: 10.1371/Journal.Ppat.1004467  0.59
2014 Calantone N, Wu F, Klase Z, Deleage C, Perkins M, Matsuda K, Thompson EA, Ortiz AM, Vinton CL, Ourmanov I, Loré K, Douek DC, Estes JD, Hirsch VM, Brenchley JM. Tissue myeloid cells in SIV-infected primates acquire viral DNA through phagocytosis of infected T cells. Immunity. 41: 493-502. PMID 25238099 DOI: 10.1016/J.Immuni.2014.08.014  0.582
2014 Del Prete GQ, Ailers B, Moldt B, Keele BF, Estes JD, Rodriguez A, Sampias M, Oswald K, Fast R, Trubey CM, Chertova E, Smedley J, LaBranche CC, Montefiori DC, Burton DR, et al. Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins. Cell Host & Microbe. 16: 412-8. PMID 25211081 DOI: 10.1016/J.Chom.2014.08.003  0.69
2014 Del Prete GQ, Shoemaker R, Oswald K, Lara A, Trubey CM, Fast R, Schneider DK, Kiser R, Coalter V, Wiles A, Wiles R, Freemire B, Keele BF, Estes JD, Quiñones OA, et al. Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques. Antimicrobial Agents and Chemotherapy. 58: 6790-806. PMID 25182644 DOI: 10.1128/Aac.03746-14  0.697
2014 Sandler NG, Bosinger SE, Estes JD, Zhu RT, Tharp GK, Boritz E, Levin D, Wijeyesinghe S, Makamdop KN, del Prete GQ, Hill BJ, Timmer JK, Reiss E, Yarden G, Darko S, et al. Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. Nature. 511: 601-5. PMID 25043006 DOI: 10.1038/Nature13554  0.722
2014 Do T, Murphy G, Earl LA, Del Prete GQ, Grandinetti G, Li GH, Estes JD, Rao P, Trubey CM, Thomas J, Spector J, Bliss D, Nath A, Lifson JD, Subramaniam S. Three-dimensional imaging of HIV-1 virological synapses reveals membrane architectures involved in virus transmission. Journal of Virology. 88: 10327-39. PMID 24965444 DOI: 10.1128/Jvi.00788-14  0.56
2014 Hatziioannou T, Del Prete GQ, Keele BF, Estes JD, McNatt MW, Bitzegeio J, Raymond A, Rodriguez A, Schmidt F, Mac Trubey C, Smedley J, Piatak M, KewalRamani VN, Lifson JD, Bieniasz PD. HIV-1-induced AIDS in monkeys. Science (New York, N.Y.). 344: 1401-5. PMID 24948736 DOI: 10.1126/Science.1250761  0.737
2014 Del Prete GQ, Park H, Fennessey CM, Reid C, Lipkey L, Newman L, Oswald K, Kahl C, Piatak M, Quiñones OA, Alvord WG, Smedley J, Estes JD, Lifson JD, Picker LJ, et al. Molecularly tagged simian immunodeficiency virus SIVmac239 synthetic swarm for tracking independent infection events. Journal of Virology. 88: 8077-90. PMID 24807714 DOI: 10.1128/Jvi.01026-14  0.636
2014 Smedley J, Turkbey B, Bernardo ML, Del Prete GQ, Estes JD, Griffiths GL, Kobayashi H, Choyke PL, Lifson JD, Keele BF. Tracking the luminal exposure and lymphatic drainage pathways of intravaginal and intrarectal inocula used in nonhuman primate models of HIV transmission. Plos One. 9: e92830. PMID 24667371 DOI: 10.1371/Journal.Pone.0092830  0.592
2014 Shive CL, Mudd JC, Funderburg NT, Sieg SF, Kyi B, Bazdar DA, Mangioni D, Gori A, Jacobson JM, Brooks AD, Hardacre J, Ammori J, Estes JD, Schacker TW, Rodriguez B, et al. Inflammatory cytokines drive CD4+ T-cell cycling and impaired responsiveness to interleukin 7: implications for immune failure in HIV disease. The Journal of Infectious Diseases. 210: 619-29. PMID 24585897 DOI: 10.1093/Infdis/Jiu125  0.581
2014 Sereti I, Estes JD, Thompson WL, Morcock DR, Fischl MA, Croughs T, Beq S, Lafaye de Micheaux S, Yao MD, Ober A, Wilson EM, Natarajan V, Imamichi H, Boulassel MR, Lederman MM, et al. Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration. Plos Pathogens. 10: e1003890. PMID 24497828 DOI: 10.1371/Journal.Ppat.1003890  0.54
2014 Hansen SG, Piatak M, Ventura AB, Hughes CM, Gilbride RM, Ford JC, Oswald K, Shoemaker R, Li Y, Lewis MS, Gilliam AN, Xu G, Whizin N, Burwitz BJ, Planer SL, ... ... Estes JD, et al. Erratum: Corrigendum: Immune clearance of highly pathogenic SIV infection Nature. 514: 654-654. DOI: 10.1038/Nature13840  0.582
2013 Ault A, Tennant SM, Gorres JP, Eckhaus M, Sandler NG, Roque A, Livio S, Bao S, Foulds KE, Kao SF, Roederer M, Schmidlein P, Boyd MA, Pasetti MF, Douek DC, ... Estes JD, et al. Safety and tolerability of a live oral Salmonella typhimurium vaccine candidate in SIV-infected nonhuman primates. Vaccine. 31: 5879-88. PMID 24099872 DOI: 10.1016/J.Vaccine.2013.09.041  0.372
2013 Hansen SG, Piatak M, Ventura AB, Hughes CM, Gilbride RM, Ford JC, Oswald K, Shoemaker R, Li Y, Lewis MS, Gilliam AN, Xu G, Whizin N, Burwitz BJ, Planer SL, ... ... Estes JD, et al. Immune clearance of highly pathogenic SIV infection. Nature. 502: 100-4. PMID 24025770 DOI: 10.1038/Nature12519  0.73
2013 Pallikkuth S, Micci L, Ende ZS, Iriele RI, Cervasi B, Lawson B, McGary CS, Rogers KA, Else JG, Silvestri G, Easley K, Estes JD, Villinger F, Pahwa S, Paiardini M. Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21. Plos Pathogens. 9: e1003471. PMID 23853592 DOI: 10.1371/Journal.Ppat.1003471  0.5
2013 Estes JD. Pathobiology of HIV/SIV-associated changes in secondary lymphoid tissues. Immunological Reviews. 254: 65-77. PMID 23772615 DOI: 10.1111/Imr.12070  0.616
2013 Cubas RA, Mudd JC, Savoye AL, Perreau M, van Grevenynghe J, Metcalf T, Connick E, Meditz A, Freeman GJ, Abesada-Terk G, Jacobson JM, Brooks AD, Crotty S, Estes JD, Pantaleo G, et al. Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nature Medicine. 19: 494-9. PMID 23475201 DOI: 10.1038/Nm.3109  0.552
2013 Canary LA, Vinton CL, Morcock DR, Pierce JB, Estes JD, Brenchley JM, Klatt NR. Rate of AIDS progression is associated with gastrointestinal dysfunction in simian immunodeficiency virus-infected pigtail macaques. Journal of Immunology (Baltimore, Md. : 1950). 190: 2959-65. PMID 23401593 DOI: 10.4049/Jimmunol.1202319  0.566
2013 Klatt NR, Canary LA, Sun X, Vinton CL, Funderburg NT, Morcock DR, Quiñones M, Deming CB, Perkins M, Hazuda DJ, Miller MD, Lederman MM, Segre JA, Lifson JD, Haddad EK, ... Estes JD, et al. Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques. The Journal of Clinical Investigation. 123: 903-7. PMID 23321668 DOI: 10.1172/Jci66227  0.595
2013 Tabb B, Morcock DR, Trubey CM, Quiñones OA, Hao XP, Smedley J, Macallister R, Piatak M, Harris LD, Paiardini M, Silvestri G, Brenchley JM, Alvord WG, Lifson JD, Estes JD. Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection. The Journal of Infectious Diseases. 207: 880-92. PMID 23087435 DOI: 10.1093/Infdis/Jis643  0.586
2013 Sandler NG, Zhu RT, Estes JD, Boritz E, Rao S, Lifson JD, Levin D, Schreiber G, Langer JA, Douek DC. 223 Cytokine. 63: 296. DOI: 10.1016/J.Cyto.2013.06.226  0.402
2012 Brenchley JM, Vinton C, Tabb B, Hao XP, Connick E, Paiardini M, Lifson JD, Silvestri G, Estes JD. Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections. Blood. 120: 4172-81. PMID 22990012 DOI: 10.1182/Blood-2012-06-437608  0.605
2012 Micci L, Cervasi B, Ende ZS, Iriele RI, Reyes-Aviles E, Vinton C, Else J, Silvestri G, Ansari AA, Villinger F, Pahwa S, Estes JD, Brenchley JM, Paiardini M. Paucity of IL-21-producing CD4(+) T cells is associated with Th17 cell depletion in SIV infection of rhesus macaques. Blood. 120: 3925-35. PMID 22990011 DOI: 10.1182/Blood-2012-04-420240  0.459
2012 Klatt NR, Estes JD, Sun X, Ortiz AM, Barber JS, Harris LD, Cervasi B, Yokomizo LK, Pan L, Vinton CL, Tabb B, Canary LA, Dang Q, Hirsch VM, Alter G, et al. Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection. Mucosal Immunology. 5: 646-57. PMID 22643849 DOI: 10.1038/Mi.2012.38  0.501
2012 Estes JD. Enhancing immune responses to limit chronic immune activation during SIV. The Journal of Clinical Investigation. 122: 1611-4. PMID 22523060 DOI: 10.1172/Jci63389  0.53
2012 Del Prete GQ, Kearney MF, Spindler J, Wiegand A, Chertova E, Roser JD, Estes JD, Hao XP, Trubey CM, Lara A, Lee K, Chaipan C, Bess JW, Nagashima K, Keele BF, et al. Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques. Journal of Virology. 86: 3152-66. PMID 22238316 DOI: 10.1128/Jvi.06886-11  0.662
2012 Sips M, Sciaranghella G, Diefenbach T, Dugast AS, Berger CT, Liu Q, Kwon D, Ghebremichael M, Estes JD, Carrington M, Martin JN, Deeks SG, Hunt PW, Alter G. Altered distribution of mucosal NK cells during HIV infection. Mucosal Immunology. 5: 30-40. PMID 21993602 DOI: 10.1038/Mi.2011.40  0.603
2011 Terio KA, Kinsel MJ, Raphael J, Mlengeya T, Lipende I, Kirchhoff CA, Gilagiza B, Wilson ML, Kamenya S, Estes JD, Keele BF, Rudicell RS, Liu W, Patton S, Collins A, et al. Pathologic lesions in chimpanzees (Pan trogylodytes schweinfurthii) from Gombe National Park, Tanzania, 2004-2010. Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians. 42: 597-607. PMID 22204054 DOI: 10.1638/2010-0237.1  0.573
2011 Ortiz AM, Klatt NR, Li B, Yi Y, Tabb B, Hao XP, Sternberg L, Lawson B, Carnathan PM, Cramer EM, Engram JC, Little DM, Ryzhova E, Gonzalez-Scarano F, Paiardini M, ... ... Estes JD, et al. Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques. The Journal of Clinical Investigation. 121: 4433-45. PMID 22005304 DOI: 10.1172/Jci46023  0.622
2011 Klatt NR, Vinton CL, Lynch RM, Canary LA, Ho J, Darrah PA, Estes JD, Seder RA, Moir SL, Brenchley JM. SIV infection of rhesus macaques results in dysfunctional T- and B-cell responses to neo and recall Leishmania major vaccination. Blood. 118: 5803-12. PMID 21960586 DOI: 10.1182/Blood-2011-07-365874  0.492
2011 Denton PW, Othieno F, Martinez-Torres F, Zou W, Krisko JF, Fleming E, Zein S, Powell DA, Wahl A, Kwak YT, Welch BD, Kay MS, Payne DA, Gallay P, Appella E, ... Estes JD, et al. One percent tenofovir applied topically to humanized BLT mice and used according to the CAPRISA 004 experimental design demonstrates partial protection from vaginal HIV infection, validating the BLT model for evaluation of new microbicide candidates. Journal of Virology. 85: 7582-93. PMID 21593172 DOI: 10.1128/Jvi.00537-11  0.448
2011 Keele BF, Estes JD. Barriers to mucosal transmission of immunodeficiency viruses. Blood. 118: 839-46. PMID 21555745 DOI: 10.1182/Blood-2010-12-325860  0.687
2011 Zeng M, Smith AJ, Wietgrefe SW, Southern PJ, Schacker TW, Reilly CS, Estes JD, Burton GF, Silvestri G, Lifson JD, Carlis JV, Haase AT. Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections. The Journal of Clinical Investigation. 121: 998-1008. PMID 21393864 DOI: 10.1172/Jci45157  0.792
2010 Gordon SN, Cervasi B, Odorizzi P, Silverman R, Aberra F, Ginsberg G, Estes JD, Paiardini M, Frank I, Silvestri G. Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals. Journal of Immunology (Baltimore, Md. : 1950). 185: 5169-79. PMID 20889546 DOI: 10.4049/Jimmunol.1001801  0.582
2010 Estes JD, Harris LD, Klatt NR, Tabb B, Pittaluga S, Paiardini M, Barclay GR, Smedley J, Pung R, Oliveira KM, Hirsch VM, Silvestri G, Douek DC, Miller CJ, Haase AT, et al. Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections. Plos Pathogens. 6: e1001052. PMID 20808901 DOI: 10.1371/Journal.Ppat.1001052  0.573
2010 Harris LD, Klatt NR, Vinton C, Briant JA, Tabb B, Ladell K, Lifson J, Estes JD, Price DA, Hirsch VM, Brenchley JM. Mechanisms underlying γδ T-cell subset perturbations in SIV-infected Asian rhesus macaques. Blood. 116: 4148-57. PMID 20660793 DOI: 10.1182/Blood-2010-05-283549  0.552
2010 Felts RL, Narayan K, Estes JD, Shi D, Trubey CM, Fu J, Hartnell LM, Ruthel GT, Schneider DK, Nagashima K, Bess JW, Bavari S, Lowekamp BC, Bliss D, Lifson JD, et al. 3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 13336-41. PMID 20624966 DOI: 10.1073/Pnas.1003040107  0.536
2010 Harris LD, Tabb B, Sodora DL, Paiardini M, Klatt NR, Douek DC, Silvestri G, Müller-Trutwin M, Vasile-Pandrea I, Apetrei C, Hirsch V, Lifson J, Brenchley JM, Estes JD. Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques. Journal of Virology. 84: 7886-91. PMID 20484518 DOI: 10.1128/Jvi.02612-09  0.458
2010 Klatt NR, Harris LD, Vinton CL, Sung H, Briant JA, Tabb B, Morcock D, McGinty JW, Lifson JD, Lafont BA, Martin MA, Levine AD, Estes JD, Brenchley JM. Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection Mucosal Immunology. 3: 387-398. PMID 20357762 DOI: 10.1038/Mi.2010.14  0.512
2010 Klatt NR, Shudo E, Ortiz AM, Engram JC, Paiardini M, Lawson B, Miller MD, Else J, Pandrea I, Estes JD, Apetrei C, Schmitz JE, Ribeiro RM, Perelson AS, Silvestri G. CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells. Plos Pathogens. 6: e1000747. PMID 20126441 DOI: 10.1371/Journal.Ppat.1000747  0.578
2010 Denton PW, Krisko JF, Powell DA, Mathias M, Kwak YT, Martinez-Torres F, Zou W, Payne DA, Estes JD, Garcia JV. Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice. Plos One. 5: e8829. PMID 20098623 DOI: 10.1371/Journal.Pone.0008829  0.508
2010 Minang JT, Trivett MT, Bolton DL, Trubey CM, Estes JD, Li Y, Smedley J, Pung R, Rosati M, Jalah R, Pavlakis GN, Felber BK, Piatak M, Roederer M, Lifson JD, et al. Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous simian immunodeficiency virus-specific CD8+ T cell clones in rhesus macaques during acute infection. Journal of Immunology (Baltimore, Md. : 1950). 184: 315-26. PMID 19949091 DOI: 10.4049/Jimmunol.0902410  0.579
2009 Sodora DL, Allan JS, Apetrei C, Brenchley JM, Douek DC, Else JG, Estes JD, Hahn BH, Hirsch VM, Kaur A, Kirchhoff F, Muller-Trutwin M, Pandrea I, Schmitz JE, Silvestri G. Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts. Nature Medicine. 15: 861-5. PMID 19661993 DOI: 10.1038/Nm.2013  0.522
2009 Keele BF, Jones JH, Terio KA, Estes JD, Rudicell RS, Wilson ML, Li Y, Learn GH, Beasley TM, Schumacher-Stankey J, Wroblewski E, Mosser A, Raphael J, Kamenya S, Lonsdorf EV, et al. Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz. Nature. 460: 515-9. PMID 19626114 DOI: 10.1038/Nature08200  0.752
2009 Aksentijevich I, Masters SL, Ferguson PJ, Dancey P, Frenkel J, van Royen-Kerkhoff A, Laxer R, TedgÃ¥rd U, Cowen EW, Pham TH, Booty M, Estes JD, Sandler NG, Plass N, Stone DL, et al. An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. The New England Journal of Medicine. 360: 2426-37. PMID 19494218 DOI: 10.1056/Nejmoa0807865  0.331
2009 Li Q, Estes JD, Schlievert PM, Duan L, Brosnahan AJ, Southern PJ, Reilly CS, Peterson ML, Schultz-Darken N, Brunner KG, Nephew KR, Pambuccian S, Lifson JD, Carlis JV, Haase AT. Glycerol monolaurate prevents mucosal SIV transmission. Nature. 458: 1034-8. PMID 19262509 DOI: 10.1038/Nature07831  0.612
2009 Hatziioannou T, Ambrose Z, Chung NP, Piatak M, Yuan F, Trubey CM, Coalter V, Kiser R, Schneider D, Smedley J, Pung R, Gathuka M, Estes JD, Veazey RS, KewalRamani VN, et al. A macaque model of HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. 106: 4425-9. PMID 19255423 DOI: 10.1073/Pnas.0812587106  0.6
2009 Estes JD. Role of collagen deposition in lymphatic tissues and immune reconstruction during HIV-1 and SIV infections. Current Hiv/Aids Reports. 6: 29-35. PMID 19149994 DOI: 10.1007/S11904-009-0005-0  0.604
2009 Thacker TC, Zhou X, Estes JD, Jiang Y, Keele BF, Elton TS, Burton GF. Follicular dendritic cells and human immunodeficiency virus type 1 transcription in CD4+ T cells. Journal of Virology. 83: 150-8. PMID 18971284 DOI: 10.1128/Jvi.01652-08  0.843
2009 Harris LD, Estes JD, Klatt NR, Taft B, Barclay R, Douek DC, Silvestri G, Liffson J, Brenchley J. P11-01. Extensive intestinal damage underlies microbial translocation in the GI tract of chronically SIV-infected Rhesus macaques Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P146  0.362
2008 Estes J, Baker JV, Brenchley JM, Khoruts A, Barthold JL, Bantle A, Reilly CS, Beilman GJ, George ME, Douek DC, Haase AT, Schacker TW. Collagen deposition limits immune reconstitution in the gut. The Journal of Infectious Diseases. 198: 456-64. PMID 18598193 DOI: 10.1086/590112  0.546
2008 Estes JD, Haase AT, Schacker TW. The role of collagen deposition in depleting CD4+ T cells and limiting reconstitution in HIV-1 and SIV infections through damage to the secondary lymphoid organ niche. Seminars in Immunology. 20: 181-6. PMID 18595731 DOI: 10.1016/J.Smim.2008.04.002  0.569
2008 Klatt NR, Villinger F, Bostik P, Gordon SN, Pereira L, Engram JC, Mayne A, Dunham RM, Lawson B, Ratcliffe SJ, Sodora DL, Else J, Reimann K, Staprans SI, Haase AT, ... Estes JD, et al. Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys Journal of Clinical Investigation. 118: 2039-2049. PMID 18497876 DOI: 10.1172/Jci33814  0.537
2008 Estes JD, Gordon SN, Zeng M, Chahroudi AM, Dunham RM, Staprans SI, Reilly CS, Silvestri G, Haase AT. Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques. Journal of Immunology (Baltimore, Md. : 1950). 180: 6798-807. PMID 18453600 DOI: 10.4049/Jimmunol.180.10.6798  0.463
2008 Keele BF, Tazi L, Gartner S, Liu Y, Burgon TB, Estes JD, Thacker TC, Crandall KA, McArthur JC, Burton GF. Characterization of the follicular dendritic cell reservoir of human immunodeficiency virus type 1. Journal of Virology. 82: 5548-61. PMID 18385252 DOI: 10.1128/Jvi.00124-08  0.826
2008 Gordon SN, Dunham RM, Engram JC, Estes J, Wang Z, Klatt NR, Paiardini M, Pandrea IV, Apetrei C, Sodora DL, Lee HY, Haase AT, Miller MD, Kaur A, Staprans SI, et al. Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis. Journal of Virology. 82: 3725-35. PMID 18216113 DOI: 10.1128/Jvi.02408-07  0.642
2008 Li Q, Estes JD, Duan L, Jessurun J, Pambuccian S, Forster C, Wietgrefe S, Zupancic M, Schacker T, Reilly C, Carlis JV, Haase AT. Simian immunodeficiency virus-induced intestinal cell apoptosis is the underlying mechanism of the regenerative enteropathy of early infection Journal of Infectious Diseases. 197: 420-429. PMID 18199035 DOI: 10.1086/525046  0.57
2008 Denton PW, Estes JD, Sun Z, Othieno FA, Wei BL, Wege AK, Powell DA, Payne D, Haase AT, Garcia JV. Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice. Plos Medicine. 5: e16. PMID 18198941 DOI: 10.1371/Journal.Pmed.0050016  0.52
2008 Estes JD, Gordon SN, Zeng M, Chahroudi AM, Dunham RM, Staprans SI, Reilly CS, Silvestri G, Haase AT. Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques (Journal of Immunology (2008) 180, (6798-6807)) Journal of Immunology. 181: 2934.  0.308
2007 Sun Z, Denton PW, Estes JD, Othieno FA, Wei BL, Wege AK, Melkus MW, Padgett-Thomas A, Zupancic M, Haase AT, Garcia JV. Intrarectal transmission, systemic infection, and CD4+ T cell depletion in humanized mice infected with HIV-1. The Journal of Experimental Medicine. 204: 705-14. PMID 17389241 DOI: 10.1084/Jem.20062411  0.625
2007 Estes JD, Wietgrefe S, Schacker T, Southern P, Beilman G, Reilly C, Milush JM, Lifson JD, Sodora DL, Carlis JV, Haase AT. Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection. The Journal of Infectious Diseases. 195: 551-61. PMID 17230415 DOI: 10.1086/510852  0.481
2006 Melkus MW, Estes JD, Padgett-Thomas A, Gatlin J, Denton PW, Othieno FA, Wege AK, Haase AT, Garcia JV. Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1. Nature Medicine. 12: 1316-22. PMID 17057712 DOI: 10.1038/Nm1431  0.406
2006 Estes JD, Li Q, Reynolds MR, Wietgrefe S, Duan L, Schacker T, Picker LJ, Watkins DI, Lifson JD, Reilly C, Carlis J, Haase AT. Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection. The Journal of Infectious Diseases. 193: 703-12. PMID 16453267 DOI: 10.1086/500368  0.565
2005 Li Q, Lifson JD, Duan L, Schacker TW, Reilly C, Carlis J, Estes JD, Haase AT. Potential roles of follicular dendritic cell-associated osteopontin in lymphoid follicle pathology and repair and in B cell regulation in HIV-1 and SIV infection. The Journal of Infectious Diseases. 192: 1269-76. PMID 16136472 DOI: 10.1086/444430  0.571
2005 Li Q, Duan L, Estes JD, Ma ZM, Rourke T, Wang Y, Reilly C, Carlis J, Miller CJ, Haase AT. Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells. Nature. 434: 1148-52. PMID 15793562 DOI: 10.1038/Nature03513  0.575
2004 Estes JD, Thacker TC, Hampton DL, Kell SA, Keele BF, Palenske EA, Druey KM, Burton GF. Follicular dendritic cell regulation of CXCR4-mediated germinal center CD4 T cell migration. Journal of Immunology (Baltimore, Md. : 1950). 173: 6169-78. PMID 15528354 DOI: 10.4049/Jimmunol.173.10.6169  0.782
2002 Estes JD, Keele BF, Tenner-Racz K, Racz P, Redd MA, Thacker TC, Jiang Y, Lloyd MJ, Gartner S, Burton GF. Follicular dendritic cell-mediated up-regulation of CXCR4 expression on CD4 T cells and HIV pathogenesis. Journal of Immunology (Baltimore, Md. : 1950). 169: 2313-22. PMID 12193696 DOI: 10.4049/Jimmunol.169.5.2313  0.832
2002 Burton GF, Keele BF, Estes JD, Thacker TC, Gartner S. Follicular dendritic cell contributions to HIV pathogenesis. Seminars in Immunology. 14: 275-84. PMID 12163303 DOI: 10.1016/S1044-5323(02)00060-X  0.848
2002 Smith-Franklin BA, Keele BF, Tew JG, Gartner S, Szakal AK, Estes JD, Thacker TC, Burton GF. Follicular dendritic cells and the persistence of HIV infectivity: the role of antibodies and Fcgamma receptors. Journal of Immunology (Baltimore, Md. : 1950). 168: 2408-14. PMID 11859132 DOI: 10.4049/Jimmunol.168.5.2408  0.842
1976 Klement V, Gardner MB, Lhle JN, Henderson BE, Gilden RV, Estes JD, Stanley AG. Inefficient humoral immune response of lymphoma-prone wild mice to persistent leukemia virus infection Journal of the National Cancer Institute. 57: 1169-1173. PMID 187795 DOI: 10.1093/jnci/57.5.1169  0.318
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