Amir Shlomai, Ph.D. - Publications

Affiliations: 
2009 MGV Molecular Genetics Weizmann Institute of Science, Rehovot, Israel 
Area:
Genetics, Virology Biology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yu Y, Kass MA, Zhang M, Youssef N, Freije CA, Brock KP, Aguado LC, Seifert LL, Venkittu S, Hong X, Shlomai A, de Jong YP, Marks DS, Rice CM, Schneider WM. Deep mutational scanning of hepatitis B virus reveals a mechanism for cis-preferential reverse transcription. Cell. PMID 38723628 DOI: 10.1016/j.cell.2024.04.008  0.393
2023 Yu Y, Schneider WM, Kass MA, Michailidis E, Acevedo A, Pamplona Mosimann AL, Bordignon J, Koenig A, Livingston CM, van Gijzel H, Ni Y, Ambrose PM, Freije CA, Zhang M, Zou C, ... ... Shlomai A, et al. An RNA-based system to study hepatitis B virus replication and evaluate antivirals. Science Advances. 9: eadg6265. PMID 37043562 DOI: 10.1126/sciadv.adg6265  0.471
2022 Mao X, Cheung KS, Peng C, Mak LY, Cheng HM, Fung J, Peleg N, Leung HH, Kumar R, Lee JH, Shlomai A, Yuen MF, Seto WK. Steatosis, HBV-related hepatocellular carcinoma, cirrhosis & HBsAg seroclearance: a systematic review and meta-analysis. Hepatology (Baltimore, Md.). PMID 36111362 DOI: 10.1002/hep.32792  0.376
2021 Shafran N, Issachar A, Shochat T, Shafran IH, Bursztyn M, Shlomai A. Abnormal liver tests in patients with SARS-CoV-2 or influenza - prognostic similarities and temporal disparities. Jhep Reports : Innovation in Hepatology. 100258. PMID 33644724 DOI: 10.1016/j.jhepr.2021.100258  0.336
2020 Deutsch L, Houri I, Ben-Ari Z, Shlomai A, Veitsman E, Cohen-Ezra O, Issachar A, Mor O, Gozlan Y, Bruck R, Menachem Y, Zelber-Sagi S, Katchman H, Shibolet O. Ombitasvir/paritaprevir/ritonavir & dasabuvir ± ribavirin following protease inhibitors failure - a prospective multi-centre trial. Bmc Infectious Diseases. 20: 264. PMID 32245397 DOI: 10.1186/S12879-020-4921-3  0.404
2020 Taylor RS, Taylor RJ, Bayliss S, Hagstrom H, Nasr P, Schattenberg JM, Ishigami M, Toyoda H, Wai-Sun Wong V, Peleg N, Shlomai A, Sebastiani G, Seko Y, Bhala N, Younossi ZM, et al. Association Between Fibrosis Stage and Outcomes of Patients with Non-Alcoholic Fatty Liver Disease: a Systematic Review and Meta-Analysis. Gastroenterology. PMID 32027911 DOI: 10.1053/J.Gastro.2020.01.043  0.334
2020 Michailidis E, Vercauteren K, Mancio-Silva L, Andrus L, Jahan C, Ricardo-Lax I, Zou C, Kabbani M, Park P, Quirk C, Pyrgaki C, Razooky B, Verhoye L, Zoluthkin I, Lu WY, ... ... Shlomai A, et al. Expansion, in vivo-ex vivo cycling, and genetic manipulation of primary human hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31915293 DOI: 10.1073/Pnas.1919035117  0.381
2020 Berger T, Reisler I, Shochat T, Raanani P, Nesher E, Mor E, Gafter-Gvili A, Shlomai A. Post-Liver Transplantation Anemia and Its Correlation with Mortality and Graft Failure. Digestive Diseases and Sciences. PMID 31900712 DOI: 10.1007/S10620-019-06021-7  0.306
2019 Peleg N, Issachar A, Sneh Arbib O, Cohen-Naftaly M, Braun M, Leshno M, Barsheshet A, Shlomai A. Liver steatosis is a strong predictor of mortality and cancer in chronic hepatitis B regardless of viral load. Jhep Reports (Online). 1: 9-16. PMID 32039349 DOI: 10.1016/j.jhepr.2019.02.002  0.432
2019 Peleg N, Issachar A, Sneh-Arbib O, Cohen-Naftaly M, Harif Y, Oxtrud E, Braun M, Leshno M, Barsheshet A, Shlomai A. Liver steatosis is a major predictor of poor outcomes in chronic hepatitis C patients with sustained virologic response. Journal of Viral Hepatitis. PMID 31243878 DOI: 10.1111/Jvh.13167  0.393
2019 Gozlan Y, Bucris E, Shirazi R, Rakovsky A, Ben-Ari Z, Davidov Y, Veizman E, Saadi T, Braun M, Cohen-Naftaly M, Shlomai A, Shibolet O, Zigmond E, Katchman H, Menachem Y, et al. High frequency of multiclass HCV resistance-associated mutations in patients failing direct-acting antivirals: real-life data. Antiviral Therapy. PMID 30880684 DOI: 10.3851/Imp3301  0.346
2019 Michailidis E, Park P, Kabbani M, Silva LM, Yu Y, Schneider WM, Andrus L, Zou C, Vercauteren K, Jahan C, Razooky B, Quirk C, Shlomai A, Bhatia S, Rice C, et al. SAT-188-Expansion and genetic modification of primary hepatocytes to study long-term hepatitis B virus infection Journal of Hepatology. 70: e712. DOI: 10.1016/S0618-8278(19)31423-9  0.455
2019 Issachar A, Cohen-Naftaly M, Arbib OS, Tur-Kaspa R, Shlomai A, Braun M, Mei-Zahav M. FRI-433-Bevacizumab for the treatment of liver involvement in patients with hereditary hemorrhagic telangiectasia Journal of Hepatology. 70: e584-e585. DOI: 10.1016/S0618-8278(19)31170-3  0.371
2019 Peleg N, Issachar A, Cohen-Naftaly M, Arbib OS, Braun M, leshno m, barsheshet a, Shlomai A. THU-341-Liver steatosis is a strong predictor of mortality and cancer in chronic hepatitis B regardless of viral load Journal of Hepatology. 70. DOI: 10.1016/S0618-8278(19)30604-8  0.466
2019 Zuckerman E, Ashkenazi E, Kovalev Y, Cohen-ezra O, Veitsman E, Saadi T, Carlebach M, Hazzan DR, Safadi R, Goldberg T, Oren R, Ashur Y, Carmiel M, Kitay Y, Hadary R, ... ... Shlomai A, et al. THU-200-The Real-Eorld Israeli experience of treating mild and severe chronic hepatitis C patients with elbasvir/grazoprevir: A large multi-center cohort study Journal of Hepatology. 70: e251-e252. DOI: 10.1016/S0618-8278(19)30475-X  0.381
2018 Peleg N, Sneh Arbib O, Issachar A, Cohen-Naftaly M, Braun M, Shlomai A. Noninvasive scoring systems predict hepatic and extra-hepatic cancers in patients with nonalcoholic fatty liver disease. Plos One. 13: e0202393. PMID 30106985 DOI: 10.1371/Journal.Pone.0202393  0.428
2018 Shirin D, Peleg N, Sneh-Arbib O, Cohen-Naftaly M, Braun M, Shochat T, Issachar A, Shlomai A. The Pattern of Elevated Liver Function Tests in Nonalcoholic Fatty Liver Disease Predicts Fibrosis Stage and Metabolic-Associated Comorbidities. Digestive Diseases (Basel, Switzerland). 1-8. PMID 30016799 DOI: 10.1159/000491428  0.38
2018 Dukhovny A, Shlomai A, Sklan EH. The antiviral protein Viperin suppresses T7 promoter dependent RNA synthesis-possible implications for its antiviral activity. Scientific Reports. 8: 8100. PMID 29802323 DOI: 10.1038/S41598-018-26516-Z  0.335
2018 Witt-Kehati D, Fridkin A, Alaluf MB, Zemel R, Shlomai A. Inhibition of pMAPK14 Overcomes Resistance to Sorafenib in Hepatoma Cells with Hepatitis B Virus. Translational Oncology. 11: 511-517. PMID 29524828 DOI: 10.1016/J.Tranon.2018.02.015  0.515
2018 Shirazi R, Ram D, Rakovsky A, Bucris E, Gozlan Y, Lustig Y, Shaked-Mishan P, Picard O, Shemer-Avni Y, Ben-Zvi H, Halutz O, Lurie Y, Veizman E, Carlebach M, Braun M, ... ... Shlomai A, et al. Characterization of hepatitis B and delta coinfection in Israel. Bmc Infectious Diseases. 18: 97. PMID 29486716 DOI: 10.1186/S12879-018-3008-X  0.52
2017 Michailidis E, Pabon J, Xiang K, Park P, Ramanan V, Hoffmann HH, Schneider WM, Bhatia SN, de Jong YP, Shlomai A, Rice CM. A robust cell culture system supporting the complete life cycle of hepatitis B virus. Scientific Reports. 7: 16616. PMID 29192196 DOI: 10.1038/S41598-017-16882-5  0.492
2017 Peleg N, Issachar A, Sneh-Arbib O, Shlomai A. AST to Platelet Ratio Index and fibrosis 4 calculator scores for non-invasive assessment of hepatic fibrosis in patients with non-alcoholic fatty liver disease. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. PMID 28572039 DOI: 10.1016/J.Dld.2017.05.002  0.432
2017 Nesher E, Mor E, Shlomai A, Naftaly-Cohen M, Yemini R, Yussim A, Brown M, Keidar A. Simultaneous Liver Transplantation and Sleeve Gastrectomy: Prohibitive Combination or a Necessity? Obesity Surgery. PMID 28281236 DOI: 10.1007/S11695-017-2634-5  0.311
2017 Gozlan Y, Ben-Ari Z, Moscona R, Shirazi R, Rakovsky A, Kabat A, Veizman E, Berdichevski T, Weiss P, Cohen-Ezra O, Lurie Y, Gafanovich I, Braun M, Cohen-Naftaly M, Shlomai A, et al. HCV genotype-1 subtypes and resistance-associated substitutions in drug-naive and in direct-acting antiviral treatment failure patients. Antiviral Therapy. PMID 28067632 DOI: 10.3851/Imp3123  0.362
2017 Leibovici-Weissman Y, Mor E, Leshno M, Shlomai A. Patients' Age Rather Than Model of End-Stage Liver Disease Score Predicts Survival After Liver Transplantation. Digestive Diseases and Sciences. PMID 28054162 DOI: 10.1007/S10620-016-4423-8  0.332
2016 Hasin Y, Shteingart S, Dahari H, Gafanovich I, Floru S, Braun M, Shlomai A, Verstandig A, Dery I, Uprichard SL, Cotler SJ, Lurie Y. Hepatitis C virus cures after direct acting antiviral-related drug-induced liver injury: Case report. World Journal of Hepatology. 8: 858-62. PMID 27458506 DOI: 10.4254/Wjh.V8.I20.858  0.456
2016 Billerbeck E, Mommersteeg MC, Shlomai A, Xiao JW, Andrus L, Bhatta A, Vercauteren K, Michailidis E, Dorner M, Krishnan A, Charlton MR, Chiriboga L, Rice CM, de Jong YP. Humanized mice efficiently engrafted with fetal hepatoblasts and syngeneic immune cells develop human monocytes and NK cells. Journal of Hepatology. PMID 27151182 DOI: 10.1016/J.Jhep.2016.04.022  0.44
2016 Scheel TK, Luna JM, Liniger M, Nishiuchi E, Rozen-Gagnon K, Shlomai A, Auray G, Gerber M, Fak J, Keller I, Bruggmann R, Darnell RB, Ruggli N, Rice CM. A Broad RNA Virus Survey Reveals Both miRNA Dependence and Functional Sequestration. Cell Host & Microbe. 19: 409-423. PMID 26962949 DOI: 10.1016/J.Chom.2016.02.007  0.338
2016 Alaluf MB, Shlomai A. New therapies for chronic hepatitis B. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 26854115 DOI: 10.1111/Liv.13086  0.511
2016 Witt-Kehati D, Bitton Alaluf M, Shlomai A. Advances and Challenges in Studying Hepatitis B Virus In Vitro. Viruses. 8. PMID 26784218 DOI: 10.3390/V8010021  0.524
2016 Witt-Kehati D, Zemel R, Shlomai A. Hepatitis B Virus Antagonizes Sorafenib in Hepatoma Cells through Indirect Induction of the RAF-MEK-ERK Pathway Journal of Hepatology. 64: S556. DOI: 10.1016/S0168-8278(16)01001-1  0.503
2015 March S, Ramanan V, Trehan K, Ng S, Galstian A, Gural N, Scull MA, Shlomai A, Mota MM, Fleming HE, Khetani SR, Rice CM, Bhatia SN. Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens. Nature Protocols. 10: 2027-2053. PMID 26584444 DOI: 10.1038/Nprot.2015.128  0.381
2015 Shlomai A. Hepatitis C virus addiction to liver miR-122 takes its Toll on the host. Hepatology (Baltimore, Md.). 62: 1633-5. PMID 26096908 DOI: 10.1002/Hep.27947  0.436
2015 Ramanan V, Shlomai A, Cox DB, Schwartz RE, Michailidis E, Bhatta A, Scott DA, Zhang F, Rice CM, Bhatia SN. CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus. Scientific Reports. 5: 10833. PMID 26035283 DOI: 10.1038/Srep10833  0.513
2015 Ricardo-Lax I, Ramanan V, Michailidis E, Shamia T, Reuven N, Rice CM, Shlomai A, Shaul Y. Hepatitis B virus induces RNR-R2 expression via DNA damage response activation. Journal of Hepatology. PMID 26026873 DOI: 10.1016/J.Jhep.2015.05.017  0.672
2014 Shlomai A, Schwartz RE, Ramanan V, Bhatta A, de Jong YP, Bhatia SN, Rice CM. Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems. Proceedings of the National Academy of Sciences of the United States of America. 111: 12193-8. PMID 25092305 DOI: 10.1073/Pnas.1412631111  0.494
2014 Shlomai A, Rice CM. Virology. Getting rid of a persistent troublemaker to cure hepatitis. Science (New York, N.Y.). 343: 1212-3. PMID 24626921 DOI: 10.1126/Science.1252186  0.542
2014 Shlomai A, de Jong YP, Rice CM. Virus associated malignancies: the role of viral hepatitis in hepatocellular carcinoma. Seminars in Cancer Biology. 26: 78-88. PMID 24457013 DOI: 10.1016/J.Semcancer.2014.01.004  0.482
2014 Billerbeck E, Mommersteeg M, Xiao J, Dorner M, Fung C, Andrus L, Bhatta A, Shlomai A, Chiriboga L, Rice C, de Jong Y. O112 GENERATION OF MICE WITH SYNGENEIC HUMAN LIVER AND IMMUNE SYSTEM TO STUDY CELLULAR IMMUNITY TO HEPATITIS B VIRUS Journal of Hepatology. 60: S46. DOI: 10.1016/S0168-8278(14)60114-8  0.44
2013 Adamovich Y, Shlomai A, Tsvetkov P, Umansky KB, Reuven N, Estall JL, Spiegelman BM, Shaul Y. The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1. Molecular and Cellular Biology. 33: 2603-13. PMID 23648480 DOI: 10.1128/Mcb.01672-12  0.632
2013 Shlomai A, Halfon P, Goldiner I, Zelber-Sagi S, Halpern Z, Oren R, Bruck R. Serum bile acid levels as a predictor for the severity of liver fibrosis in patients with chronic hepatitis C Journal of Viral Hepatitis. 20: 95-102. PMID 23301544 DOI: 10.1111/J.1365-2893.2012.01628.X  0.425
2013 Mouler Rechtman M, Burdelova EO, Bar-Yishay I, Ben-Yehoyada M, Fishman S, Halpern Z, Shlomai A. The metabolic regulator PGC- 1α links anti- cancer cytotoxic chemotherapy to reactivation of hepatitis B virus Journal of Viral Hepatitis. 20: 34-41. PMID 23231082 DOI: 10.1111/J.1365-2893.2012.01622.X  0.475
2013 Halfon P, Goldiner I, Zelber-Sagi S, Halpern Z, Oren R, Shlomai A, Bruck R. P1: New non-invasive model, based on serum bile acid levels and patient's parameters for liver fibrosis assessment in patients with chronic hepatitis C Journal of Viral Hepatitis. 20: 16-16. DOI: 10.1111/Jvh.12166  0.437
2012 Shlomai A. Targeting late SV40 factor: is the achilles heel of hepatocarcinogenesis revealed? World Journal of Gastroenterology. 18: 6709-11. PMID 23239907 DOI: 10.3748/Wjg.V18.I46.6709  0.371
2012 Shlomai A, Rechtman MM, Burdelova EO, Zilberberg A, Hoffman S, Solar I, Fishman S, Halpern Z, Sklan EH. The metabolic regulator PGC-1α links hepatitis C virus infection to hepatic insulin resistance. Journal of Hepatology. 57: 867-73. PMID 22732512 DOI: 10.1016/J.Jhep.2012.06.021  0.44
2012 Ben-Shlomo S, Einstein FH, Zvibel I, Atias D, Shlomai A, Halpern Z, Barzilai N, Fishman S. Perinephric and epididymal fat affect hepatic metabolism in rats. Obesity (Silver Spring, Md.). 20: 151-6. PMID 21818154 DOI: 10.1038/Oby.2011.261  0.352
2011 Zelber-Sagi S, Yeshua H, Shlomai A, Blendis L, Leshno M, Levit S, Halpern Z, Oren R. Sampling variability of transient elastography according to probe location. European Journal of Gastroenterology & Hepatology. 23: 507-14. PMID 21537125 DOI: 10.1097/Meg.0B013E328346C0F7  0.354
2011 Bar-Yishay I, Shaul Y, Shlomai A. Hepatocyte metabolic signalling pathways and regulation of hepatitis B virus expression. Liver International : Official Journal of the International Association For the Study of the Liver. 31: 282-90. PMID 21281428 DOI: 10.1111/J.1478-3231.2010.02423.X  0.719
2011 Ben-Shlomo S, Zvibel I, Shnell M, Shlomai A, Chepurko E, Halpern Z, Barzilai N, Oren R, Fishman S. Glucagon-like peptide-1 reduces hepatic lipogenesis via activation of AMP-activated protein kinase. Journal of Hepatology. 54: 1214-23. PMID 21145820 DOI: 10.1016/J.Jhep.2010.09.032  0.351
2011 Mouler Rechtman M, Bar-Yishay I, Ben-Yehoyada M, Halpern Z, Shlomai A. 1122 THE METABOLIC REGULATOR PGC-1 ALPHA LINKS CANCER CHEMOTHERAPY TO HEPATITIS B VIRUS REACTIVATION Journal of Hepatology. 54: S444. DOI: 10.1016/S0168-8278(11)61124-0  0.456
2010 Rechtman MM, Har-Noy O, Bar-Yishay I, Fishman S, Adamovich Y, Shaul Y, Halpern Z, Shlomai A. Curcumin inhibits hepatitis B virus via down-regulation of the metabolic coactivator PGC-1alpha. Febs Letters. 584: 2485-90. PMID 20434445 DOI: 10.1016/J.Febslet.2010.04.067  0.705
2010 Rechtman MM, Har-Noy O, Bar-Yishay I, Fishman S, Adamovich Y, Shaul Y, Halpern Z, Shlomai A. Erratum to “Curcumin inhibits hepatitis B virus via down-regulation of the metabolic coactivator PGC-1α” [FEBS Lett. 584 (2010) 2485-2490] Febs Letters. 584: 3239-3239. DOI: 10.1016/J.Febslet.2010.05.041  0.669
2009 Shlomai A, Lubelsky Y, Har-Noy O, Shaul Y. The "Trojan horse" model-delivery of anti-HBV small interfering RNAs by a recombinant HBV vector. Biochemical and Biophysical Research Communications. 390: 619-23. PMID 19818740 DOI: 10.1016/J.Bbrc.2009.10.016  0.739
2009 Shlomai A, Shaul Y. The metabolic activator FOXO1 binds hepatitis B virus DNA and activates its transcription. Biochemical and Biophysical Research Communications. 381: 544-8. PMID 19233123 DOI: 10.1016/J.Bbrc.2009.02.078  0.688
2008 Shlomai A, Shaul Y. The "metabolovirus" model of hepatitis B virus suggests nutritional therapy as an effective anti-viral weapon. Medical Hypotheses. 71: 53-7. PMID 18334285 DOI: 10.1016/J.Mehy.2007.08.032  0.713
2006 Shlomai A, Paran N, Shaul Y. PGC-1alpha controls hepatitis B virus through nutritional signals. Proceedings of the National Academy of Sciences of the United States of America. 103: 16003-8. PMID 17043229 DOI: 10.1073/Pnas.0607837103  0.684
2004 Shlomai A, Shaul Y. RNA interference--small RNAs effectively fight viral hepatitis. Liver International : Official Journal of the International Association For the Study of the Liver. 24: 526-31. PMID 15566500 DOI: 10.1111/J.1478-3231.2004.0960.X  0.632
2003 Shlomai A, Shaul Y. Inhibition of hepatitis B virus expression and replication by RNA interference. Hepatology (Baltimore, Md.). 37: 764-70. PMID 12668968 DOI: 10.1053/Jhep.2003.50146  0.651
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