| Year |
Citation |
Score |
| 2024 |
Chen C, Kumbhar R, Wang H, Yang X, Gadhave K, Rastegar C, Kimura Y, Behensky A, Kotha S, Kuo G, Katakam S, Jeong D, Wang L, Wang A, Chen R, et al. Lymphocyte-Activation Gene 3 Facilitates Pathological Tau Neuron-to-Neuron Transmission. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2303775. PMID 38327094 DOI: 10.1002/advs.202303775 |
0.308 |
|
| 2023 |
Ubba V, Joseph S, Awe O, Jones D, Dsilva MK, Feng M, Wang J, Fu X, Akbar RJ, Bodnar BH, Hu W, Wang H, Yang X, Yang L, Yang P, et al. Reproductive Profile of Neuronal Androgen Receptor Knockout Female Mice with Low Dose of DHT. Endocrinology. PMID 38156784 DOI: 10.1210/endocr/bqad199 |
0.305 |
|
| 2023 |
Zhou W, Yang X, Wang H, Yao W, Chu D, Wu F. Neuronal aerobic glycolysis exacerbates synapse loss in aging mice. Experimental Neurology. 371: 114590. PMID 37907123 DOI: 10.1016/j.expneurol.2023.114590 |
0.319 |
|
| 2023 |
Ubba V, Joseph S, Awe O, Jones D, Dsilva MK, Feng M, Wang J, Fu X, Akbar RJ, Bodnar BH, Hu W, Wang H, Yang X, Yang L, Yang P, et al. Neuronal AR regulates glucose homeostasis and energy expenditure in lean female mice with androgen excess. Endocrinology. PMID 37738624 DOI: 10.1210/endocr/bqad141 |
0.322 |
|
| 2023 |
Wang J, Gao Y, Xiao L, Lin Y, Huang L, Chen J, Liang G, Li W, Yi W, Lao J, Zhang B, Gao TM, Zhong M, Yang X. Increased NMDARs in neurons and glutamine synthetase in astrocytes underlying autistic-like behaviors of mice. Iscience. 26: 107476. PMID 37599823 DOI: 10.1016/j.isci.2023.107476 |
0.33 |
|
| 2023 |
Korff A, Yang X, O'Donovan K, Gonzalez A, Teubner BJ, Nakamura H, Messing J, Yang F, Carisey AF, Wang YD, Patni T, Sheppard H, Zakharenko SS, Chook YM, Taylor JP, et al. A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1. The Journal of Clinical Investigation. 133. PMID 37463454 DOI: 10.1172/JCI160309 |
0.309 |
|
| 2023 |
O'Reilly D, Belgrad J, Ferguson C, Summers A, Sapp E, McHugh C, Mathews E, Boudi A, Buchwald J, Ly S, Moreno D, Furgal R, Luu E, Kennedy Z, Hariharan V, ... ... Yang XW, et al. Di-valent siRNA Mediated Silencing of MSH3 Blocks Somatic Repeat Expansion in Mouse Models of Huntington's Disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 37177784 DOI: 10.1016/j.ymthe.2023.05.006 |
0.321 |
|
| 2023 |
Yu J, Yang X, Zheng J, Sgobio C, Sun L, Cai H. Deficiency of Perry syndrome-associated p150 in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities. Npj Parkinson's Disease. 9: 35. PMID 36879021 DOI: 10.1038/s41531-023-00478-0 |
0.334 |
|
| 2022 |
Wang B, Zhao M, Su Z, Jin B, Yang X, Zhang C, Guo B, Li J, Hong W, Liu J, Zhao Y, Hou Y, Lai F, Zhang W, Qin L, et al. RIIβ-PKA in GABAergic Neurons of Dorsal Median Hypothalamus Governs White Adipose Browning. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2205173. PMID 36529950 DOI: 10.1002/advs.202205173 |
0.319 |
|
| 2022 |
Yang X, Yin H, Wang X, Sun Y, Bian X, Zhang G, Li A, Cao A, Li B, Ebrahimi-Fakhari D, Yang Z, Meisler MH, Liu Q. Social Deficits and Cerebellar Degeneration in Purkinje Cell Knockout Mice. Frontiers in Molecular Neuroscience. 15: 822129. PMID 35557557 DOI: 10.3389/fnmol.2022.822129 |
0.301 |
|
| 2022 |
Su XJ, Shen BD, Wang K, Song QX, Yang X, Wu DS, Shen HX, Zhu C. Roles of the Neuron-Restrictive Silencer Factor in the Pathophysiological Process of the Central Nervous System. Frontiers in Cell and Developmental Biology. 10: 834620. PMID 35300407 DOI: 10.3389/fcell.2022.834620 |
0.31 |
|
| 2022 |
Gu X, Richman J, Langfelder P, Wang N, Zhang S, Bañez-Coronel M, Wang HB, Yang L, Ramanathan L, Deng L, Park CS, Choi CR, Cantle JP, Gao F, Gray M, ... ... Yang XW, et al. Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice. Neuron. PMID 35114102 DOI: 10.1016/j.neuron.2022.01.006 |
0.554 |
|
| 2020 |
Victor MB, Richner M, Olsen HE, Lee SW, Monteys AM, Ma C, Huh CJ, Zhang B, Davidson BL, Yang XW, Yoo AS. Author Correction: Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Nature Neuroscience. PMID 32879483 DOI: 10.1038/S41593-020-00714-3 |
0.366 |
|
| 2020 |
Veldman MB, Park CS, Eyermann CM, Zhang JY, Zuniga-Sanchez E, Hirano AA, Daigle TL, Foster NN, Zhu M, Langfelder P, Lopez IA, Brecha NC, Zipursky SL, Zeng H, Dong HW, ... Yang XW, et al. Brainwide Genetic Sparse Cell Labeling to Illuminate the Morphology of Neurons and Glia with Cre-Dependent MORF Mice. Neuron. PMID 32795398 DOI: 10.1016/J.Neuron.2020.07.019 |
0.426 |
|
| 2020 |
Lee CYD, Yang XW. Huntington's Disease: Genome-wide Neuroprotection Screening Goes Viral. Neuron. 106: 4-6. PMID 32272066 DOI: 10.1016/J.Neuron.2020.03.020 |
0.36 |
|
| 2019 |
Tian X, Richard A, El-Saadi MW, Bhandari A, Latimer B, Van Savage I, Holmes K, Klein RL, Dwyer D, Goeders NE, Yang XW, Lu XH. Dosage sensitivity intolerance of VIPR2 microduplication is disease causative to manifest schizophrenia-like phenotypes in a novel BAC transgenic mouse model. Molecular Psychiatry. PMID 31444475 DOI: 10.1038/S41380-019-0492-3 |
0.712 |
|
| 2019 |
Li R, Zhu M, Li J, Bienkowski MS, Foster NN, Xu H, Ard T, Bowman I, Zhou C, Veldman MB, Yang XW, Hintiryan H, Zhang J, Dong HW. Precise segmentation of densely interweaving neuron clusters using G-Cut. Nature Communications. 10: 1549. PMID 30948706 DOI: 10.1038/S41467-019-09515-0 |
0.339 |
|
| 2019 |
Wang N, Yang XW. Huntington Disease's Glial Progenitor Cells Hit the Pause Button in the Mouse Brain. Cell Stem Cell. 24: 3-4. PMID 30609397 DOI: 10.1016/J.Stem.2018.12.004 |
0.322 |
|
| 2018 |
Lee CYD, Daggett A, Gu X, Jiang LL, Langfelder P, Li X, Wang N, Zhao Y, Park CS, Cooper Y, Ferando I, Mody I, Coppola G, Xu H, Yang XW. Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models. Neuron. 97: 1032-1048.e5. PMID 29518357 DOI: 10.1016/J.Neuron.2018.02.002 |
0.435 |
|
| 2018 |
Victor MB, Richner M, Olsen HE, Lee SW, Monteys AM, Ma C, Huh CJ, Zhang B, Davidson BL, Yang XW, Yoo AS. Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Nature Neuroscience. PMID 29403030 DOI: 10.1038/S41593-018-0075-7 |
0.439 |
|
| 2018 |
Langfelder P, Gao F, Wang N, Howland D, Kwak S, Vogt TF, Aaronson JS, Rosinski J, Coppola G, Horvath S, Yang XW. MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice. Plos One. 13: e0190550. PMID 29324753 DOI: 10.1371/Journal.Pone.0190550 |
0.374 |
|
| 2017 |
Veldman MB, Yang XW. Molecular insights into cortico-striatal miscommunications in Huntington's disease. Current Opinion in Neurobiology. 48: 79-89. PMID 29125980 DOI: 10.1016/J.Conb.2017.10.019 |
0.434 |
|
| 2017 |
Veldman MB, Yang XW. Huntington's Disease: Nuclear Gatekeepers Under Attack. Neuron. 94: 1-4. PMID 28384467 DOI: 10.1016/J.Neuron.2017.03.032 |
0.335 |
|
| 2017 |
Lu XH, Yang XW. Genetically-directed Sparse Neuronal Labeling in BAC Transgenic Mice through Mononucleotide Repeat Frameshift. Scientific Reports. 7: 43915. PMID 28272512 DOI: 10.1038/Srep43915 |
0.738 |
|
| 2016 |
Yang XW. Life and death rest on a bivalent chromatin state. Nature Neuroscience. 19: 1271-1273. PMID 27669984 DOI: 10.1038/Nn.4396 |
0.398 |
|
| 2016 |
Xu J, Bernstein AM, Wong A, Lu XH, Khoja S, Yang XW, Davies DL, Micevych P, Sofroniew MV, Khakh BS. P2X4 Receptor Reporter Mice: Sparse Brain Expression and Feeding-Related Presynaptic Facilitation in the Arcuate Nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8902-20. PMID 27559172 DOI: 10.1523/Jneurosci.1496-16.2016 |
0.721 |
|
| 2016 |
Kratter IH, Zahed H, Lau A, Tsvetkov AS, Daub AC, Weiberth KF, Gu X, Saudou F, Humbert S, Yang XW, Osmand A, Steffan JS, Masliah E, Finkbeiner S. Serine 421 regulates mutant huntingtin toxicity and clearance in mice. The Journal of Clinical Investigation. PMID 27525439 DOI: 10.1172/Jci80339 |
0.444 |
|
| 2016 |
Hintiryan H, Foster NN, Bowman I, Bay M, Song MY, Gou L, Yamashita S, Bienkowski MS, Zingg B, Zhu M, Yang XW, Shih JC, Toga AW, Dong HW. The mouse cortico-striatal projectome. Nature Neuroscience. PMID 27322419 DOI: 10.1038/Nn.4332 |
0.306 |
|
| 2016 |
Chandra A, Sharma A, Calingasan NY, White JM, Shurubor Y, Yang XW, Beal MF, Johri A. Enhanced Mitochondrial Biogenesis Ameliorates Disease Phenotype in a Full-Length Mouse Model of Huntington's Disease. Human Molecular Genetics. PMID 27008868 DOI: 10.1093/Hmg/Ddw095 |
0.442 |
|
| 2016 |
Langfelder P, Cantle JP, Chatzopoulou D, Wang N, Gao F, Al-Ramahi I, Lu XH, Ramos EM, El-Zein K, Zhao Y, Deverasetty S, Tebbe A, Schaab C, Lavery DJ, Howland D, ... ... Yang XW, et al. Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice. Nature Neuroscience. PMID 26900923 DOI: 10.1038/Nn.4256 |
0.713 |
|
| 2015 |
Veldman MB, Rios-Galdamez Y, Lu XH, Gu X, Qin W, Li S, Yang XW, Lin S. The N17 domain mitigates nuclear toxicity in a novel zebrafish Huntington's disease model. Molecular Neurodegeneration. 10: 67. PMID 26645399 DOI: 10.1186/S13024-015-0063-2 |
0.706 |
|
| 2015 |
Park CS, Yang XW. Probing the stress and depression circuits with a disease gene. Elife. 4. PMID 26371507 DOI: 10.7554/Elife.10829 |
0.314 |
|
| 2015 |
Estrada-Sánchez AM, Burroughs CL, Cavaliere S, Barton SJ, Chen S, Yang XW, Rebec GV. Cortical efferents lacking mutant huntingtin improve striatal neuronal activity and behavior in a conditional mouse model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4440-51. PMID 25762686 DOI: 10.1523/JNEUROSCI.2812-14.2015 |
0.4 |
|
| 2015 |
Gu X, Cantle JP, Greiner ER, Lee CY, Barth AM, Gao F, Park CS, Zhang Z, Sandoval-Miller S, Zhang RL, Diamond M, Mody I, Coppola G, Yang XW. N17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic mice. Neuron. 85: 726-41. PMID 25661181 DOI: 10.1016/J.Neuron.2015.01.008 |
0.457 |
|
| 2015 |
Peñagarikano O, Lázaro MT, Lu XH, Gordon A, Dong H, Lam HA, Peles E, Maidment NT, Murphy NP, Yang XW, Golshani P, Geschwind DH. Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism. Science Translational Medicine. 7: 271ra8. PMID 25609168 DOI: 10.1126/Scitranslmed.3010257 |
0.707 |
|
| 2014 |
Lu XH, Mattis VB, Wang N, Al-Ramahi I, van den Berg N, Fratantoni SA, Waldvogel H, Greiner E, Osmand A, Elzein K, Xiao J, Dijkstra S, de Pril R, Vinters HV, Faull R, ... ... Yang XW, et al. Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease. Science Translational Medicine. 6: 268ra178. PMID 25540325 DOI: 10.1126/Scitranslmed.3010523 |
0.718 |
|
| 2014 |
Wang N, Gray M, Lu XH, Cantle JP, Holley SM, Greiner E, Gu X, Shirasaki D, Cepeda C, Li Y, Dong H, Levine MS, Yang XW. Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease. Nature Medicine. 20: 536-41. PMID 24784230 DOI: 10.1038/Nm.3514 |
0.776 |
|
| 2014 |
Haustein MD, Kracun S, Lu XH, Shih T, Jackson-Weaver O, Tong X, Xu J, Yang XW, O'Dell TJ, Marvin JS, Ellisman MH, Bushong EA, Looger LL, Khakh BS. Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway. Neuron. 82: 413-29. PMID 24742463 DOI: 10.1016/J.Neuron.2014.02.041 |
0.634 |
|
| 2014 |
Cui Y, Ostlund SB, James AS, Park CS, Ge W, Roberts KW, Mittal N, Murphy NP, Cepeda C, Kieffer BL, Levine MS, Jentsch JD, Walwyn WM, Sun YE, Evans CJ, ... ... Yang XW, et al. Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward. Nature Neuroscience. 17: 254-61. PMID 24413699 DOI: 10.1038/Nn.3622 |
0.781 |
|
| 2013 |
Wang N, Lu XH, Sandoval SV, Yang XW. An independent study of the preclinical efficacy of C2-8 in the R6/2 transgenic mouse model of Huntington's disease. Journal of Huntington's Disease. 2: 443-51. PMID 25062731 DOI: 10.3233/Jhd-130074 |
0.692 |
|
| 2013 |
Daggett A, Yang XW. Huntington's disease: easing the NMDAR traffic jam. Nature Medicine. 19: 971-3. PMID 23921742 DOI: 10.1038/Nm.3283 |
0.365 |
|
| 2013 |
Lee CY, Cantle JP, Yang XW. Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis. The Febs Journal. 280: 4382-94. PMID 23829302 DOI: 10.1111/Febs.12418 |
0.472 |
|
| 2013 |
Southwell AL, Warby SC, Carroll JB, Doty CN, Skotte NH, Zhang W, Villanueva EB, Kovalik V, Xie Y, Pouladi MA, Collins JA, Yang XW, Franciosi S, Hayden MR. A fully humanized transgenic mouse model of Huntington disease. Human Molecular Genetics. 22: 18-34. PMID 23001568 DOI: 10.1093/Hmg/Dds397 |
0.426 |
|
| 2012 |
Yu-Taeger L, Petrasch-Parwez E, Osmand AP, Redensek A, Metzger S, Clemens LE, Park L, Howland D, Calaminus C, Gu X, Pichler B, Yang XW, Riess O, Nguyen HP. A novel BACHD transgenic rat exhibits characteristic neuropathological features of Huntington disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15426-38. PMID 23115180 DOI: 10.1523/Jneurosci.1148-12.2012 |
0.412 |
|
| 2012 |
Shirasaki DI, Greiner ER, Al-Ramahi I, Gray M, Boontheung P, Geschwind DH, Botas J, Coppola G, Horvath S, Loo JA, Yang XW. Network organization of the huntingtin proteomic interactome in mammalian brain. Neuron. 75: 41-57. PMID 22794259 DOI: 10.1016/J.Neuron.2012.05.024 |
0.484 |
|
| 2012 |
Lu XH, Yang XW. "Huntingtin holiday": progress toward an antisense therapy for Huntington's disease. Neuron. 74: 964-6. PMID 22726826 DOI: 10.1016/J.Neuron.2012.06.001 |
0.686 |
|
| 2012 |
Gafni J, Papanikolaou T, Degiacomo F, Holcomb J, Chen S, Menalled L, Kudwa A, Fitzpatrick J, Miller S, Ramboz S, Tuunanen PI, Lehtimäki KK, Yang XW, Park L, Kwak S, et al. Caspase-6 activity in a BACHD mouse modulates steady-state levels of mutant huntingtin protein but is not necessary for production of a 586 amino acid proteolytic fragment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7454-65. PMID 22649225 DOI: 10.1523/Jneurosci.6379-11.2012 |
0.387 |
|
| 2012 |
Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, ... ... Yang XW, et al. Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nature Medicine. 18: 153-8. PMID 22179319 DOI: 10.1038/Nm.2558 |
0.457 |
|
| 2012 |
Yang XW. Novel circuitry and molecular pathogenic mechanisms in Huntington's disease Molecular Neurodegeneration. 7: 1-1. DOI: 10.1186/1750-1326-7-S1-L18 |
0.468 |
|
| 2012 |
Miller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, ... ... Yang XW, et al. Erratum: Corrigendum: Identifying polyglutamine protein species in situ that best predict neurodegeneration Nature Chemical Biology. 8: 318-318. DOI: 10.1038/Nchembio0312-318A |
0.427 |
|
| 2012 |
Cantle JP, Lu XH, Gu X, Yang XW. Cellular and molecular mechanisms implicated in pathogenesis of selective neurodegeneration in Huntington's disease Frontiers in Biology. 7: 459-476. DOI: 10.1007/S11515-012-1246-7 |
0.722 |
|
| 2011 |
Miller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, ... ... Yang XW, et al. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nature Chemical Biology. 7: 925-34. PMID 22037470 DOI: 10.1038/Nchembio.694 |
0.497 |
|
| 2011 |
Greiner ER, Yang XW. Huntington's disease: flipping a switch on huntingtin. Nature Chemical Biology. 7: 412-4. PMID 21685885 DOI: 10.1038/Nchembio.604 |
0.343 |
|
| 2011 |
Tao J, Wu H, Lin Q, Wei W, Lu XH, Cantle JP, Ao Y, Olsen RW, Yang XW, Mody I, Sofroniew MV, Sun YE. Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8306-19. PMID 21632951 DOI: 10.1523/Jneurosci.0567-11.2011 |
0.703 |
|
| 2011 |
Wilburn B, Rudnicki DD, Zhao J, Weitz TM, Cheng Y, Gu X, Greiner E, Park CS, Wang N, Sopher BL, La Spada AR, Osmand A, Margolis RL, Sun YE, Yang XW. An antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington's disease-like 2 mice. Neuron. 70: 427-40. PMID 21555070 DOI: 10.1016/J.Neuron.2011.03.021 |
0.748 |
|
| 2011 |
Yang XW, Lu XH. Molecular and cellular basis of obsessive-compulsive disorder-like behaviors: emerging view from mouse models. Current Opinion in Neurology. 24: 114-8. PMID 21386675 DOI: 10.1097/Wco.0B013E32834451Fb |
0.687 |
|
| 2011 |
André VM, Cepeda C, Fisher YE, Huynh M, Bardakjian N, Singh S, Yang XW, Levine MS. Differential electrophysiological changes in striatal output neurons in Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1170-82. PMID 21273402 DOI: 10.1523/Jneurosci.3539-10.2011 |
0.403 |
|
| 2011 |
Yang Z, Jiang H, Chaichanasakul T, Gong S, Yang XW, Heintz N, Lin S. Corrigendum to " Modified bacterial artificial chromosomes for zebrafish transgenesis" Methods 39 (2006) 183-188 Methods. 53: 327. DOI: 10.1016/J.Ymeth.2010.11.001 |
0.395 |
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| 2010 |
Graham RK, Deng Y, Carroll J, Vaid K, Cowan C, Pouladi MA, Metzler M, Bissada N, Wang L, Faull RL, Gray M, Yang XW, Raymond LA, Hayden MR. Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15019-29. PMID 21068307 DOI: 10.1523/Jneurosci.2071-10.2010 |
0.536 |
|
| 2010 |
Pouladi MA, Xie Y, Skotte NH, Ehrnhoefer DE, Graham RK, Kim JE, Bissada N, Yang XW, Paganetti P, Friedlander RM, Leavitt BR, Hayden MR. Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expression. Human Molecular Genetics. 19: 1528-38. PMID 20097678 DOI: 10.1093/Hmg/Ddq026 |
0.352 |
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| 2010 |
Karsten SL, Parfenova L, Lau K, Vi N, Hui M, Gray M, Yang XW, Hui K, Kudo LC. P1-369: Overexpression of puromycin sensitive aminopeptidase (PSA/NPEPPS) reduces soluble tau and delays development of neuropathology in PSA/TAU-P301L double transgenic mice Alzheimer's & Dementia. 6: S280-S280. DOI: 10.1016/J.Jalz.2010.05.923 |
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| 2009 |
Gu X, Greiner ER, Mishra R, Kodali R, Osmand A, Finkbeiner S, Steffan JS, Thompson LM, Wetzel R, Yang XW. Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice. Neuron. 64: 828-40. PMID 20064390 DOI: 10.1016/J.Neuron.2009.11.020 |
0.46 |
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| 2009 |
Menalled L, El-Khodor BF, Patry M, Suárez-Fariñas M, Orenstein SJ, Zahasky B, Leahy C, Wheeler V, Yang XW, MacDonald M, Morton AJ, Bates G, Leeds J, Park L, Howland D, et al. Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models. Neurobiology of Disease. 35: 319-36. PMID 19464370 DOI: 10.1016/J.Nbd.2009.05.007 |
0.39 |
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| 2009 |
Hutnick LK, Golshani P, Namihira M, Xue Z, Matynia A, Yang XW, Silva AJ, Schweizer FE, Fan G. DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Human Molecular Genetics. 18: 2875-88. PMID 19433415 DOI: 10.1093/Hmg/Ddp222 |
0.614 |
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| 2009 |
Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1962-76. PMID 19228951 DOI: 10.1523/Jneurosci.5351-08.2009 |
0.728 |
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| 2009 |
Kudo LC, Vi N, Lau K, Parfenova L, Hui M, Gray M, Yang X, Wiedau-Pazos M, Hui K, Karsten S. P3-205: Effect of puromycin sensitive aminopeptidase overexpression on TAU protein metabolism in vivo Alzheimer's & Dementia. 5: P403-P403. DOI: 10.1016/J.Jalz.2009.04.978 |
0.447 |
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| 2008 |
Spampanato J, Gu X, Yang XW, Mody I. Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease. Neuroscience. 157: 606-20. PMID 18854207 DOI: 10.1016/J.Neuroscience.2008.09.020 |
0.318 |
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| 2008 |
Gray M, Shirasaki DI, Cepeda C, André VM, Wilburn B, Lu XH, Tao J, Yamazaki I, Li SH, Sun YE, Li XJ, Levine MS, Yang XW. Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6182-95. PMID 18550760 DOI: 10.1523/Jneurosci.0857-08.2008 |
0.78 |
|
| 2008 |
Lobo MK, Yeh C, Yang XW. Pivotal role of early B-cell factor 1 in development of striatonigral medium spiny neurons in the matrix compartment. Journal of Neuroscience Research. 86: 2134-46. PMID 18338816 DOI: 10.1002/Jnr.21666 |
0.665 |
|
| 2007 |
Lobo MK, Cui Y, Ostlund SB, Balleine BW, Yang XW. Genetic control of instrumental conditioning by striatopallidal neuron-specific S1P receptor Gpr6. Nature Neuroscience. 10: 1395-7. PMID 17934457 DOI: 10.1038/Nn1987 |
0.77 |
|
| 2007 |
Gu X, André VM, Cepeda C, Li SH, Li XJ, Levine MS, Yang XW. Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease. Molecular Neurodegeneration. 2: 8. PMID 17470275 DOI: 10.1186/1750-1326-2-8 |
0.456 |
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| 2006 |
Yang Z, Jiang H, Chaichanasakul T, Chachainasakul T, Gong S, Yang XW, Heintz N, Lin S. Modified bacterial artificial chromosomes for zebrafish transgenesis. Methods (San Diego, Calif.). 39: 183-8. PMID 16828309 DOI: 10.1016/j.ymeth.2006.04.011 |
0.469 |
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| 2006 |
Lobo MK, Karsten SL, Gray M, Geschwind DH, Yang XW. FACS-array profiling of striatal projection neuron subtypes in juvenile and adult mouse brains. Nature Neuroscience. 9: 443-52. PMID 16491081 DOI: 10.1038/Nn1654 |
0.698 |
|
| 2005 |
Gong S, Yang XW. Modification of bacterial artificial chromosomes (BACs) and preparation of intact BAC DNA for generation of transgenic mice. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.21. PMID 18428623 DOI: 10.1002/0471142301.Ns0521S31 |
0.37 |
|
| 2005 |
Yang XW, Gong S. An overview on the generation of BAC transgenic mice for neuroscience research. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.20. PMID 18428622 DOI: 10.1002/0471142301.Ns0520S31 |
0.434 |
|
| 2005 |
Gu X, Li C, Wei W, Lo V, Gong S, Li SH, Iwasato T, Itohara S, Li XJ, Mody I, Heintz N, Yang XW. Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. Neuron. 46: 433-44. PMID 15882643 DOI: 10.1016/J.Neuron.2005.03.025 |
0.629 |
|
| 2002 |
Gong S, Yang XW, Li C, Heintz N. Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication. Genome Research. 12: 1992-8. PMID 12466304 DOI: 10.1101/Gr.476202 |
0.46 |
|
| 2001 |
Misulovin Z, Yang XW, Yu W, Heintz N, Meffre E. A rapid method for targeted modification and screening of recombinant bacterial artificial chromosome. Journal of Immunological Methods. 257: 99-105. PMID 11687243 DOI: 10.1016/S0022-1759(01)00452-5 |
0.446 |
|
| 1999 |
Yang XW, Wynder C, Doughty ML, Heintz N. BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin. Nature Genetics. 22: 327-35. PMID 10431235 DOI: 10.1038/11896 |
0.529 |
|
| 1997 |
Yang XW, Model P, Heintz N. Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome. Nature Biotechnology. 15: 859-65. PMID 9306400 DOI: 10.1038/Nbt0997-859 |
0.513 |
|
| 1996 |
Yang XW, Zhong R, Heintz N. Granule cell specification in the developing mouse brain as defined by expression of the zinc finger transcription factor RU49. Development (Cambridge, England). 122: 555-66. PMID 8625807 |
0.527 |
|
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