| Year |
Citation |
Score |
| 2023 |
Weld ED, McGowan I, Anton P, Fuchs EJ, Ho K, Carballo-Dieguez A, Rohan LC, Giguere R, Brand R, Edick S, Bakshi RP, Parsons T, Manohar M, Seigel A, Engstrom J, et al. Tenofovir Douche as HIV Pre-Exposure Prophylaxis for Receptive Anal Intercourse: Safety, Acceptability, Pharmacokinetics, & Pharmacodynamics (DREAM 01). The Journal of Infectious Diseases. PMID 38019657 DOI: 10.1093/infdis/jiad535 |
0.318 |
|
| 2023 |
Patel SK, Agashe H, Patton DL, Sweeney Y, Beamer MA, Hendrix CW, Hillier SL, Rohan LC. Tenofovir vaginal film as a potential MPT product against HIV-1 and HSV-2 acquisition: formulation development and preclinical assessment in non-human primates. Frontiers in Reproductive Health. 5: 1217835. PMID 37638127 DOI: 10.3389/frph.2023.1217835 |
0.408 |
|
| 2022 |
Tong X, Patel SK, Li J, Patton D, Xu E, Anderson PL, Parikh U, Sweeney Y, Strizki J, Hillier SL, Rohan LC. Development and Evaluation of Nanoparticles-in-Film Technology to Achieve Extended In Vivo Exposure of MK-2048 for HIV Prevention. Polymers. 14. PMID 35335526 DOI: 10.3390/polym14061196 |
0.41 |
|
| 2021 |
Jhunjhunwala K, Dobard CW, Sharma S, Makarova N, Holder A, Dinh C, Mitchell J, Wang L, Zhang J, Patel SK, Heneine W, Rohan LC. Development, Characterization and In Vivo Pharmacokinetic Assessment of Rectal Suppositories Containing Combination Antiretroviral Drugs for HIV Prevention. Pharmaceutics. 13. PMID 34452070 DOI: 10.3390/pharmaceutics13081110 |
0.417 |
|
| 2021 |
McGowan IM, Chawki S, Hendrix CW, Anton PA, Marzinke MA, Brand RM, Engstrom JC, Rohan LC, Abebe KZ, Richardson-Harman N, Siegel A, Rinehart A, Steytler J, Stall R, Spiegel H, et al. A Randomized, Open Label, Crossover Phase 1 Safety and Pharmacokinetic Study of Oral Maraviroc and Maraviroc 1% Gel (the CHARM-03 Study). Aids Research and Human Retroviruses. PMID 34384282 DOI: 10.1089/AID.2021.0096 |
0.319 |
|
| 2021 |
Kramzer LF, Hamorsky KT, Graebing PW, Wang L, Fuqua JL, Matoba N, Lasnik AB, Moncla BJ, Zhang J, Palmer KE, Rohan LC. Preformulation Characterization of Griffithsin, a Biopharmaceutical Candidate for HIV Prevention. Aaps Pharmscitech. 22: 83. PMID 33625602 DOI: 10.1208/s12249-021-01931-0 |
0.36 |
|
| 2020 |
Guthrie KM, Fava JL, Vargas S, Rosen RK, Shaw JG, Kojic EM, Ham A, Rohan LC, Katz D, Panameño A, Colleran C, Friend DF, Buckheit KW, Buckheit RW. The role of volume in the perceptibility of topical vaginal formulations: User sensory perceptions and experiences (USPEs) of heterosexual couples during vaginal sex. Aids Research and Human Retroviruses. PMID 32988214 DOI: 10.1089/AID.2020.0138 |
0.343 |
|
| 2019 |
Li J, Regev G, Patel SK, Patton D, Sweeney Y, Graebing P, Grab S, Wang L, Sant V, Rohan LC. Rational Design of a Multipurpose Bioadhesive Vaginal Film for Co-Delivery of Dapivirine and Levonorgestrel. Pharmaceutics. 12. PMID 31861267 DOI: 10.3390/Pharmaceutics12010001 |
0.497 |
|
| 2019 |
Günaydın G, Edfeldt G, Garber DA, Asghar M, Noȅl-Romas L, Burgener A, Wählby C, Wang L, Rohan LC, Guenthner P, Mitchell J, Matoba N, McNicholl JM, Palmer KE, Tjernlund A, et al. Impact of Q-Griffithsin anti-HIV microbicide gel in non-human primates: In situ analyses of epithelial and immune cell markers in rectal mucosa. Scientific Reports. 9: 18120. PMID 31792342 DOI: 10.1038/S41598-019-54493-4 |
0.337 |
|
| 2019 |
McKinley D, Patel SK, Regev G, Rohan LC, Akil A. Delineating the Effects of Hot-Melt Extrusion on the Performance of a Polymeric Film using Artificial Neural Networks and an Evolutionary Algorithm. International Journal of Pharmaceutics. 118715. PMID 31560958 DOI: 10.1016/J.Ijpharm.2019.118715 |
0.337 |
|
| 2019 |
Gong T, Patel SK, Parniak MA, Ballou B, Rohan LC. Nanocrystal Formulation Improves Vaginal Delivery of CSIC for HIV Prevention. Aaps Pharmscitech. 20: 286. PMID 31410664 DOI: 10.1208/S12249-019-1503-Z |
0.484 |
|
| 2019 |
Regev G, Patel SK, Moncla BJ, Twist J, Devlin B, Rohan LC. Novel Application of Hot Melt Extrusion for the Manufacturing of Vaginal Films Containing Microbicide Candidate Dapivirine. Aaps Pharmscitech. 20: 239. PMID 31243640 DOI: 10.1208/S12249-019-1442-8 |
0.382 |
|
| 2019 |
Yang H, Li J, Patel SK, Palmer KE, Devlin B, Rohan LC. Design of Poly(lactic--glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis. Pharmaceutics. 11. PMID 30995761 DOI: 10.3390/Pharmaceutics11040184 |
0.555 |
|
| 2018 |
Grab S, Rohan LC. A Quantitative Disintegration Method for Polymeric Films. Journal of Pharmaceutical Innovation. 13: 321-329. PMID 30559901 DOI: 10.1007/S12247-018-9325-1 |
0.341 |
|
| 2018 |
Koppolu S, Wang L, Mathur A, Nigam JA, Dezzutti CS, Isaacs C, Meyn L, Bunge KE, Moncla BJ, Hillier SL, Rohan LC, Mahal LK. Vaginal Product Formulation Alters the Innate Anti-viral Activity and Glycome of Cervicovaginal Fluids with Implications for Viral Susceptibility. Acs Infectious Diseases. PMID 30183260 DOI: 10.1021/Acsinfecdis.8B00157 |
0.431 |
|
| 2018 |
Bunge KE, Dezzutti CS, Hendrix CW, Marzinke MA, Spiegel HML, Moncla BJ, Schwartz JL, Meyn LA, Richardson-Harman N, Rohan LC, Hillier SL. FAME-04: A Phase 1 trial to assess the safety, acceptability, pharmacokinetics and pharmacodynamics of film and gel formulations of tenofovir. Journal of the International Aids Society. 21: e25156. PMID 30101439 DOI: 10.1002/Jia2.25156 |
0.419 |
|
| 2018 |
Hillier SL, Cummins JE, Rohan LC. Charlene Susan Dezzutti (1964-2018) Virologist with a Passion for HIV Prevention. Aids Research and Human Retroviruses. 34: 475-476. PMID 29888975 DOI: 10.1089/Aid.2018.29003.Hil |
0.45 |
|
| 2018 |
Feturi FG, Weinstock M, Zhao W, Zhang W, Schnider JT, Erbas VE, Oksuz S, Plock JA, Rohan L, Spiess AM, Ferreira LM, Solari MG, Venkataramanan R, Gorantla VS. Mycophenolic Acid for Topical Immunosuppression in Vascularized Composite Allotransplantation: Optimizing Formulation and Preliminary Evaluation of Bioavailability and Pharmacokinetics. Frontiers in Surgery. 5: 20. PMID 29868602 DOI: 10.3389/Fsurg.2018.00020 |
0.34 |
|
| 2018 |
Hoang T, Date AA, Ortiz Ortiz J, Young TW, Bensouda S, Xiao P, Marzinke M, Rohan L, Fuchs EJ, Hendrix C, Gumber S, Villinger F, Cone RA, Hanes J, Ensign LM. Development of rectal enema as microbicide (DREAM): Preclinical progressive selection of a tenofovir prodrug enema. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 29802984 DOI: 10.1016/J.Ejpb.2018.05.030 |
0.454 |
|
| 2018 |
Girard L, Birse K, Holm JB, Gajer P, Humphrys MS, Garber D, Guenthner P, Noël-Romas L, Abou M, McCorrister S, Westmacott G, Wang L, Rohan LC, Matoba N, McNicholl J, et al. Impact of the griffithsin anti-HIV microbicide and placebo gels on the rectal mucosal proteome and microbiome in non-human primates. Scientific Reports. 8: 8059. PMID 29795295 DOI: 10.1038/S41598-018-26313-8 |
0.425 |
|
| 2018 |
Kay K, Shah DK, Rohan L, Bies R. Physiologically-based pharmacokinetic model of vaginally administered dapivirine ring and film formulations. British Journal of Clinical Pharmacology. PMID 29714824 DOI: 10.1111/Bcp.13625 |
0.415 |
|
| 2017 |
Robinson JA, Marzinke MA, Fuchs EJ, Bakshi RP, Spiegel HML, Coleman JS, Rohan LC, Hendrix CW. Comparison Of The Pharmacokinetics And Pharmacodynamics Of Single-Dose Tenofovir Vaginal Film And Gel Formulation (Fame-05). Journal of Acquired Immune Deficiency Syndromes (1999). PMID 29135651 DOI: 10.1097/Qai.0000000000001587 |
0.464 |
|
| 2017 |
Xiao P, Gumber S, Marzinke MA, Date AA, Hoang T, Hanes J, Ensign LM, Wang L, Rohan L, Fuchs EJ, Hendrix C, Villinger F. Hypo-osmolar formulation of TFV enema promotes uptake and metabolism of TFV in tissues and leading to prevention of SHIV/SIV infection. Antimicrobial Agents and Chemotherapy. PMID 29084755 DOI: 10.1128/Aac.01644-17 |
0.387 |
|
| 2017 |
Gong T, Zhang W, Parniak MA, Graebing PW, Moncla B, Gupta P, Empey KM, Rohan LC. Preformulation and Vaginal Film Formulation Development of Microbicide Drug Candidate CSIC for HIV prevention. Journal of Pharmaceutical Innovation. 12: 142-154. PMID 28983328 DOI: 10.1007/S12247-017-9274-0 |
0.529 |
|
| 2017 |
Chuchuen O, Maher JR, Henderson MH, Desoto M, Rohan LC, Wax A, Katz DF. Label-free analysis of tenofovir delivery to vaginal tissue using co-registered confocal Raman spectroscopy and optical coherence tomography. Plos One. 12: e0185633. PMID 28961280 DOI: 10.1371/Journal.Pone.0185633 |
0.361 |
|
| 2017 |
M Guthrie K, Rohan L, Rosen RK, Vargas SE, Ham AS, Friend D, Katz D, Shaw JG, Kojic EM, Buckheit KW, Buckheit RW. Vaginal Film for Prevention of HIV: Using Visual and Tactile Evaluations among Potential Users to Inform Product Design. Pharmaceutical Development and Technology. 1-12. PMID 28592183 DOI: 10.1080/10837450.2017.1339085 |
0.372 |
|
| 2017 |
Patel SK, Rohan LC. On-demand microbicide products: design matters. Drug Delivery and Translational Research. PMID 28589452 DOI: 10.1007/S13346-017-0385-4 |
0.415 |
|
| 2016 |
Robinson JA, Marzinke MA, Bakshi RP, Fuchs EJ, Radebaugh C, Aung WS, Spiegel H, Coleman JS, Rohan LC, Hendrix CW. Comparison of dapivirine vaginal gel and film formulation pharmacokinetics and pharmacodynamics (FAME 02B). Aids Research and Human Retroviruses. PMID 27809557 DOI: 10.1089/Aid.2016.0040 |
0.505 |
|
| 2016 |
Hu M, Zhou T, Dezzutti CS, Rohan LC. The Effect of Commonly Used Excipients on the Epithelial Integrity of Human Cervicovaginal Tissue. Aids Research and Human Retroviruses. PMID 27611224 DOI: 10.1089/Aid.2016.0014 |
0.509 |
|
| 2016 |
Fan MD, Kramzer LF, Hillier SL, Chang JC, Meyn LA, Rohan LC. Preferred Physical Characteristics of Vaginal Film Microbicides for HIV Prevention in Pittsburgh Women. Archives of Sexual Behavior. PMID 27571742 DOI: 10.1007/S10508-016-0816-1 |
0.454 |
|
| 2016 |
Zhou T, Hu M, Pearlman A, Rohan LC. Expression, Regulation, and Function of Drug Transporters in Cervicovaginal Tissues of a Mouse Model Used for Microbicide Testing. Biochemical Pharmacology. PMID 27453435 DOI: 10.1016/J.Bcp.2016.07.009 |
0.308 |
|
| 2016 |
Dezzutti CS, Richardson-Harman N, Rohan LC, Marzinke MA, Hoesley CJ, Panther L, Johnson S, Nuttall JP, Nel A, Chen BA. Pharmacodynamic correlations using fresh and cryopreserved tissue following use of vaginal rings containing dapivirine and/or maraviroc in a randomized, placebo controlled trial. Medicine. 95: e4174. PMID 27428211 DOI: 10.1097/Md.0000000000004174 |
0.402 |
|
| 2015 |
Bunge KE, Dezzutti CS, Rohan LC, Hendrix CW, Marzinke MA, Richardson-Harman N, Moncla BJ, Devlin B, Meyn LA, Spiegel HM, Hillier SL. A Phase 1 trial to assess the safety, acceptability, pharmacokinetics and pharmacodynamics of a novel dapivirine vaginal film. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 26565716 DOI: 10.1097/Qai.0000000000000897 |
0.404 |
|
| 2015 |
Hu M, Patel SK, Zhou T, Rohan LC. Drug transporters in tissues and cells relevant to sexual transmission of HIV: Implications for drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26278511 DOI: 10.1016/J.Jconrel.2015.08.018 |
0.427 |
|
| 2015 |
Hiruy H, Fuchs EJ, Marzinke MA, Bakshi RP, Breakey JC, Aung WS, Manohar M, Yue C, Caffo BS, Du Y, Abebe KZ, Spiegel H, Rohan LC, McGowan I, Hendrix CW. A Phase 1 Randomized, Blinded Comparison of the Pharmacokinetics and Colonic Distribution of Three Candidate Rectal Microbicide Formulations of Tenofovir 1% Gel with Simulated Unprotected Sex (CHARM-02). Aids Research and Human Retroviruses. PMID 26227279 DOI: 10.1089/Aid.2015.0098 |
0.367 |
|
| 2015 |
Dezzutti CS, Yandura S, Wang L, Moncla B, Teeple EA, Devlin B, Nuttall J, Brown ER, Rohan LC. Pharmacodynamic Activity of Dapivirine and Maraviroc Single Entity and Combination Topical Gels for HIV-1 Prevention. Pharmaceutical Research. PMID 26078001 DOI: 10.1007/S11095-015-1738-7 |
0.472 |
|
| 2015 |
Dobard CW, Taylor A, Sharma S, Anderson PL, Bushman LR, Chuong D, Pau CP, Hanson D, Wang L, Garcia-Lerma JG, McGowan I, Rohan L, Heneine W. Protection Against Rectal Chimeric Simian/Human Immunodeficiency Virus Transmission in Macaques by Rectal-Specific Gel Formulations of Maraviroc and Tenofovir. The Journal of Infectious Diseases. PMID 26071566 DOI: 10.1093/Infdis/Jiv334 |
0.494 |
|
| 2015 |
Leyva FJ, Fuchs EJ, Bakshi RP, Carballo-Diéguez A, Ventuneac A, Yue C, Caffo BS, Du Y, Torbenson MS, Li L, Mullin GE, Lee LA, Rohan LC, Anton PA, Hendrix CW. Simultaneous evaluation of safety, acceptability, peri-coital kinetics, and ex vivo pharmacodynamics comparing four rectal microbicide vehicle candidates. Aids Research and Human Retroviruses. PMID 26066390 DOI: 10.1089/Aid.2015.0086 |
0.481 |
|
| 2015 |
Kramzer LF, Cohen J, Schubert J, Dezzutti CS, Moncla BJ, Friend D, Rohan LC. Assessing the potential of the Woman's Condom for vaginal drug delivery. Contraception. 92: 254-60. PMID 25998936 DOI: 10.1016/J.Contraception.2015.05.005 |
0.349 |
|
| 2015 |
Holt JD, Cameron D, Dias N, Holding J, Muntendam A, Oostebring F, Dreier P, Rohan L, Nuttall J. The Sheep as a Model of Preclinical Safety and Pharmacokinetic Evaluations of Candidate Microbicides. Antimicrobial Agents and Chemotherapy. 59: 3761-70. PMID 25845860 DOI: 10.1128/Aac.04954-14 |
0.406 |
|
| 2015 |
Zhang W, Hu M, Shi Y, Gong T, Dezzutti CS, Moncla B, Sarafianos SG, Parniak MA, Rohan LC. Vaginal Microbicide Film Combinations of Two Reverse Transcriptase Inhibitors, EFdA and CSIC, for the Prevention of HIV-1 Sexual Transmission. Pharmaceutical Research. PMID 25794967 DOI: 10.1007/S11095-015-1678-2 |
0.499 |
|
| 2015 |
Akil A, Agashe H, Dezzutti CS, Moncla BJ, Hillier SL, Devlin B, Shi Y, Uranker K, Rohan LC. Formulation and characterization of polymeric films containing combinations of antiretrovirals (ARVs) for HIV prevention. Pharmaceutical Research. 32: 458-68. PMID 25079391 DOI: 10.1007/S11095-014-1474-4 |
0.532 |
|
| 2014 |
Dezzutti CS, Russo J, Wang L, Abebe KZ, Li J, Friend DR, McGowan IM, Rohan LC. Development of HIV-1 rectal-specific microbicides and colonic tissue evaluation. Plos One. 9: e102585. PMID 25025306 DOI: 10.1371/Journal.Pone.0102585 |
0.5 |
|
| 2014 |
Michailidis E, Huber AD, Ryan EM, Ong YT, Leslie MD, Matzek KB, Singh K, Marchand B, Hagedorn AN, Kirby KA, Rohan LC, Kodama EN, Mitsuya H, Parniak MA, Sarafianos SG. 4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) inhibits HIV-1 reverse transcriptase with multiple mechanisms. The Journal of Biological Chemistry. 289: 24533-48. PMID 24970894 DOI: 10.1074/Jbc.M114.562694 |
0.408 |
|
| 2014 |
Zhou T, Hu M, Pearlman A, Patton D, Rohan L. Expression and localization of p-glycoprotein, multidrug resistance protein 4, and breast cancer resistance protein in the female lower genital tract of human and pigtailed macaque. Aids Research and Human Retroviruses. 30: 1106-16. PMID 24803409 DOI: 10.1089/Aid.2013.0281 |
0.314 |
|
| 2014 |
Rinehart M, Grab S, Rohan L, Katz D, Wax A. Analysis of vaginal microbicide film hydration kinetics by quantitative imaging refractometry. Plos One. 9: e95005. PMID 24736376 DOI: 10.1371/Journal.Pone.0095005 |
0.374 |
|
| 2014 |
Akil A, Devlin B, Cost M, Rohan LC. Increased Dapivirine tissue accumulation through vaginal film codelivery of dapivirine and Tenofovir. Molecular Pharmaceutics. 11: 1533-41. PMID 24693866 DOI: 10.1021/Mp4007024 |
0.519 |
|
| 2014 |
Zhang W, Parniak MA, Sarafianos SG, Empey PE, Rohan LC. In vitro transport characteristics of EFdA, a novel nucleoside reverse transcriptase inhibitor using Caco-2 and MDCKII cell monolayers. European Journal of Pharmacology. 732: 86-95. PMID 24690257 DOI: 10.1016/J.Ejphar.2014.03.022 |
0.414 |
|
| 2014 |
Zhang W, Parniak MA, Sarafianos SG, Cost MR, Rohan LC. Development of a vaginal delivery film containing EFdA, a novel anti-HIV nucleoside reverse transcriptase inhibitor. International Journal of Pharmaceutics. 461: 203-13. PMID 24333452 DOI: 10.1016/J.Ijpharm.2013.11.056 |
0.465 |
|
| 2014 |
Rohan LC, Devlin B, Yang H. Microbicide dosage forms. Current Topics in Microbiology and Immunology. 383: 27-54. PMID 24220751 DOI: 10.1007/82_2013_357 |
0.526 |
|
| 2014 |
Zhang W, Parniak MA, Mitsuya H, Sarafianos SG, Graebing PW, Rohan LC. Preformulation studies of EFdA, a novel nucleoside reverse transcriptase inhibitor for HIV prevention. Drug Development and Industrial Pharmacy. 40: 1101-11. PMID 23841536 DOI: 10.3109/03639045.2013.809535 |
0.412 |
|
| 2013 |
Rohan LC, Yang H, Wang L. Rectal pre-exposure prophylaxis (PrEP). Antiviral Research. 100: S17-24. PMID 24188705 DOI: 10.1016/J.Antiviral.2013.09.023 |
0.579 |
|
| 2013 |
Hachiya A, Reeve AB, Marchand B, Michailidis E, Ong YT, Kirby KA, Leslie MD, Oka S, Kodama EN, Rohan LC, Mitsuya H, Parniak MA, Sarafianos SG. Evaluation of combinations of 4'-ethynyl-2-fluoro-2'-deoxyadenosine with clinically used antiretroviral drugs. Antimicrobial Agents and Chemotherapy. PMID 23796932 DOI: 10.1128/Aac.00283-13 |
0.344 |
|
| 2013 |
Obitte NC, Rohan LC, Adeyeye CM, Parniak MA, Esimone CO. The utility of self-emulsifying oil formulation to improve the poor solubility of the anti HIV drug CSIC. Aids Research and Therapy. 10: 14. PMID 23721408 DOI: 10.1186/1742-6405-10-14 |
0.463 |
|
| 2013 |
Zhou T, Hu M, Cost M, Poloyac S, Rohan L. Short communication: expression of transporters and metabolizing enzymes in the female lower genital tract: implications for microbicide research. Aids Research and Human Retroviruses. 29: 1496-503. PMID 23607746 DOI: 10.1089/Aid.2013.0032 |
0.34 |
|
| 2013 |
Tasoglu S, Rohan LC, Katz DF, Szeri AJ. Transient swelling, spreading, and drug delivery by a dissolved anti-HIV microbicide-bearing film. Physics of Fluids (Woodbury, N.Y. : 1994). 25: 31901. PMID 23554549 DOI: 10.1063/1.4793598 |
0.434 |
|
| 2013 |
Nixon B, Stefanidou M, Mesquita PM, Fakioglu E, Segarra T, Rohan L, Halford W, Palmer KE, Herold BC. Griffithsin protects mice from genital herpes by preventing cell-to-cell spread. Journal of Virology. 87: 6257-69. PMID 23536670 DOI: 10.1128/Jvi.00012-13 |
0.432 |
|
| 2013 |
Wood MP, Cole AL, Ruchala P, Waring AJ, Rohan LC, Marx P, Tarwater PM, Gupta P, Cole AM. A compensatory mutation provides resistance to disparate HIV fusion inhibitor peptides and enhances membrane fusion. Plos One. 8: e55478. PMID 23393582 DOI: 10.1371/Journal.Pone.0055478 |
0.372 |
|
| 2013 |
Gao X, Huang Y, Makhov AM, Epperly M, Lu J, Grab S, Zhang P, Rohan L, Xie XQ, Wipf P, Greenberger J, Li S. Nanoassembly of surfactants with interfacial drug-interactive motifs as tailor-designed drug carriers. Molecular Pharmaceutics. 10: 187-98. PMID 23244299 DOI: 10.1021/Mp300319M |
0.348 |
|
| 2013 |
Eade CR, Cole AL, Diaz C, Rohan LC, Parniak MA, Marx P, Tarwater PM, Gupta P, Cole AM. The anti-HIV microbicide candidate RC-101 inhibits pathogenic vaginal bacteria without harming endogenous flora or mucosa. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 69: 150-8. PMID 23167830 DOI: 10.1111/Aji.12036 |
0.482 |
|
| 2013 |
Gupta P, Lackman-Smith C, Snyder B, Ratner D, Rohan LC, Patton D, Ramratnam B, Cole AM. Antiviral activity of retrocyclin RC-101, a candidate microbicide against cell-associated HIV-1. Aids Research and Human Retroviruses. 29: 391-6. PMID 22924614 DOI: 10.1089/Aid.2012.0135 |
0.467 |
|
| 2013 |
Cole AM, Patton DL, Rohan LC, Cole AL, Cosgrove-Sweeney Y, Rogers NA, Ratner D, Sassi AB, Lackman-Smith C, Tarwater P, Ramratnam B, Ruchala P, Lehrer RI, Waring AJ, Gupta P. Colposcopy of the cervicovagina reveals no adverse effects of RC-101 films. Plos One. DOI: 10.1371/Journal.Pone.0015111.G003 |
0.742 |
|
| 2013 |
Patton DL, Sweeney YC, Rohan LC, Hillier SL. P3.365 Tenofovir Vaginal Film: Safety Assessment in the Macaque Model Sexually Transmitted Infections. 89: A263.2-A263. DOI: 10.1136/Sextrans-2013-051184.0818 |
0.405 |
|
| 2012 |
Yang H, Parniak MA, Hillier SL, Rohan LC. A thermodynamic study of the cyclodextrin-UC781 inclusion complex using a HPLC method. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 72: 459-465. PMID 26097403 DOI: 10.1007/S10847-011-0019-2 |
0.502 |
|
| 2012 |
Dezzutti CS, Brown ER, Moncla B, Russo J, Cost M, Wang L, Uranker K, Kunjara Na Ayudhya RP, Pryke K, Pickett J, Leblanc MA, Rohan LC. Is wetter better? An evaluation of over-the-counter personal lubricants for safety and anti-HIV-1 activity. Plos One. 7: e48328. PMID 23144863 DOI: 10.1371/Journal.Pone.0048328 |
0.504 |
|
| 2012 |
Huang Y, Lu J, Gao X, Li J, Zhao W, Sun M, Stolz DB, Venkataramanan R, Rohan LC, Li S. PEG-derivatized embelin as a dual functional carrier for the delivery of paclitaxel. Bioconjugate Chemistry. 23: 1443-51. PMID 22681537 DOI: 10.1021/Bc3000468 |
0.33 |
|
| 2012 |
Gupta P, Ratner D, Ding M, Patterson B, Rohan LC, Reinhart TA, Ayyavoo V, Huang X, Patton DL, Ramratnam B, Cole AM. Retrocyclin RC-101 blocks HIV-1 transmission across cervical mucosa in an organ culture. Journal of Acquired Immune Deficiency Syndromes (1999). 60: 455-61. PMID 22592582 DOI: 10.1097/Qai.0B013E318258B420 |
0.428 |
|
| 2012 |
Dezzutti CS, Rohan LC, Wang L, Uranker K, Shetler C, Cost M, Lynam JD, Friend D. Reformulated tenofovir gel for use as a dual compartment microbicide. The Journal of Antimicrobial Chemotherapy. 67: 2139-42. PMID 22581908 DOI: 10.1093/Jac/Dks173 |
0.425 |
|
| 2012 |
Cost M, Dezzutti CS, Clark MR, Friend DR, Akil A, Rohan LC. Characterization of UC781-tenofovir combination gel products for HIV-1 infection prevention in an ex vivo ectocervical model. Antimicrobial Agents and Chemotherapy. 56: 3058-66. PMID 22430977 DOI: 10.1128/Aac.06284-11 |
0.526 |
|
| 2012 |
Ham AS, Rohan LC, Boczar A, Yang L, W Buckheit K, Buckheit RW. Vaginal film drug delivery of the pyrimidinedione IQP-0528 for the prevention of HIV infection. Pharmaceutical Research. 29: 1897-907. PMID 22392331 DOI: 10.1007/S11095-012-0715-7 |
0.541 |
|
| 2012 |
Agashe H, Hu M, Rohan L. Formulation and delivery of microbicides. Current Hiv Research. 10: 88-96. PMID 22264050 DOI: 10.2174/157016212799304599 |
0.466 |
|
| 2012 |
Moncla BJ, Pryke K, Rohan LC, Yang H. Testing of viscous anti-HIV microbicides using Lactobacillus. Journal of Microbiological Methods. 88: 292-6. PMID 22226641 DOI: 10.1016/j.mimet.2011.12.013 |
0.592 |
|
| 2012 |
Wang L, Sassi AB, Patton D, Isaacs C, Moncla BJ, Gupta P, Rohan LC. Development of a liposome microbicide formulation for vaginal delivery of octylglycerol for HIV prevention. Drug Development and Industrial Pharmacy. 38: 995-1007. PMID 22149387 DOI: 10.3109/03639045.2011.637048 |
0.799 |
|
| 2011 |
Akil A, Parniak MA, Dezzuitti CS, Moncla BJ, Cost MR, Li M, Rohan LC. Development and Characterization of a Vaginal Film Containing Dapivirine, a Non- nucleoside Reverse Transcriptase Inhibitor (NNRTI), for prevention of HIV-1 sexual transmission. Drug Delivery and Translational Research. 1: 209-222. PMID 22708075 DOI: 10.1007/S13346-011-0022-6 |
0.523 |
|
| 2011 |
Ferguson LM, Rohan LC. The importance of the vaginal delivery route for antiretrovirals in HIV prevention. Therapeutic Delivery. 2: 1535-50. PMID 22468220 DOI: 10.4155/tde.11.126 |
0.445 |
|
| 2011 |
Rinehart MT, Drake TK, Robles FE, Rohan LC, Katz D, Wax A. Time-resolved imaging refractometry of microbicidal films using quantitative phase microscopy. Journal of Biomedical Optics. 16: 120510. PMID 22191912 DOI: 10.1117/1.3665439 |
0.304 |
|
| 2011 |
Li M, Patton DL, Cosgrove-Sweeney Y, Ratner D, Rohan LC, Cole AM, Tarwater PM, Gupta P, Ramratnam B. Incorporation of the HIV-1 microbicide cyanovirin-N in a food product. Journal of Acquired Immune Deficiency Syndromes (1999). 58: 379-84. PMID 21926631 DOI: 10.1097/Qai.0B013E31823643Fe |
0.439 |
|
| 2011 |
Mahalingam A, Jay JI, Langheinrich K, Shukair S, McRaven MD, Rohan LC, Herold BC, Hope TJ, Kiser PF. Inhibition of the transport of HIV in vitro using a pH-responsive synthetic mucin-like polymer system. Biomaterials. 32: 8343-55. PMID 21875751 DOI: 10.1016/J.Biomaterials.2011.05.001 |
0.357 |
|
| 2011 |
Sassi AB, Bunge KE, Hood BL, Conrads TP, Cole AM, Gupta P, Rohan LC. Preformulation and stability in biological fluids of the retrocyclin RC-101, a potential anti-HIV topical microbicide. Aids Research and Therapy. 8: 27. PMID 21801426 DOI: 10.1186/1742-6405-8-27 |
0.765 |
|
| 2011 |
Wang L, Schnaare RL, Dezzutti C, Anton PA, Rohan LC. Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations. Aids Research and Therapy. 8: 12. PMID 21385339 DOI: 10.1186/1742-6405-8-12 |
0.313 |
|
| 2011 |
Sassi AB, Cost MR, Cole AL, Cole AM, Patton DL, Gupta P, Rohan LC. Formulation development of retrocyclin 1 analog RC-101 as an anti-HIV vaginal microbicide product. Antimicrobial Agents and Chemotherapy. 55: 2282-9. PMID 21321138 DOI: 10.1128/Aac.01190-10 |
0.791 |
|
| 2011 |
Mahalingam A, Simmons AP, Ugaonkar SR, Watson KM, Dezzutti CS, Rohan LC, Buckheit RW, Kiser PF. Vaginal microbicide gel for delivery of IQP-0528, a pyrimidinedione analog with a dual mechanism of action against HIV-1. Antimicrobial Agents and Chemotherapy. 55: 1650-60. PMID 21245437 DOI: 10.1128/Aac.01368-10 |
0.473 |
|
| 2011 |
Fan M, Ferguson L, Rohan L, Meyn L, Hillier S. P2-S9.06 Vaginal film microbicides for HIV prevention: a mixed methods study of women's preferences Sexually Transmitted Infections. 87: A263-A263. DOI: 10.1136/Sextrans-2011-050108.392 |
0.467 |
|
| 2010 |
Cole AM, Patton DL, Rohan LC, Cole AL, Cosgrove-Sweeney Y, Rogers NA, Ratner D, Sassi AB, Lackman-Smith C, Tarwater P, Ramratnam B, Ruchala P, Lehrer RI, Waring AJ, Gupta P. The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques. Plos One. 5: e15111. PMID 21124745 DOI: 10.1371/Journal.Pone.0015111 |
0.791 |
|
| 2010 |
Garg S, Goldman D, Krumme M, Rohan LC, Smoot S, Friend DR. Advances in development, scale-up and manufacturing of microbicide gels, films, and tablets. Antiviral Research. 88: S19-29. PMID 21109064 DOI: 10.1016/J.Antiviral.2010.09.010 |
0.513 |
|
| 2010 |
Mallipeddi R, Rohan LC. Progress in antiretroviral drug delivery using nanotechnology. International Journal of Nanomedicine. 5: 533-47. PMID 20957115 |
0.402 |
|
| 2010 |
Rohan LC, Moncla BJ, Kunjara Na Ayudhya RP, Cost M, Huang Y, Gai F, Billitto N, Lynam JD, Pryke K, Graebing P, Hopkins N, Rooney JF, Friend D, Dezzutti CS. In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide. Plos One. 5: e9310. PMID 20174579 DOI: 10.1371/Journal.Pone.0009310 |
0.438 |
|
| 2010 |
Mallipeddi R, Rohan LC. Nanoparticle-based vaginal drug delivery systems for HIV prevention. Expert Opinion On Drug Delivery. 7: 37-48. PMID 20017659 DOI: 10.1517/17425240903338055 |
0.488 |
|
| 2010 |
Mallipeddi R, Rohan LC. Progress in antiretroviral drug delivery using nanotechnology International Journal of Nanomedicine. 5: 533-547. DOI: 10.2147/Ijn.S7681 |
0.498 |
|
| 2009 |
Rohan LC, Sassi AB. Vaginal drug delivery systems for HIV prevention. The Aaps Journal. 11: 78-87. PMID 19194802 DOI: 10.1208/S12248-009-9082-7 |
0.782 |
|
| 2009 |
Ham AS, Cost MR, Sassi AB, Dezzutti CS, Rohan LC. Targeted delivery of PSC-RANTES for HIV-1 prevention using biodegradable nanoparticles. Pharmaceutical Research. 26: 502-11. PMID 19002569 DOI: 10.1007/S11095-008-9765-2 |
0.78 |
|
| 2008 |
Romano J, Malcolm RK, Garg S, Rohan LC, Kaptur PE. Microbicide delivery: formulation technologies and strategies. Current Opinion in Hiv and Aids. 3: 558-66. PMID 19373022 DOI: 10.1097/Coh.0B013E328305B96E |
0.407 |
|
| 2008 |
Yang H, Parniak MA, Isaacs CE, Hillier SL, Rohan LC. Characterization of cyclodextrin inclusion complexes of the anti-HIV non-nucleoside reverse transcriptase inhibitor UC781. The Aaps Journal. 10: 606-13. PMID 19089644 DOI: 10.1208/S12248-008-9070-3 |
0.481 |
|
| 2008 |
Sassi AB, Isaacs CE, Moncla BJ, Gupta P, Hillier SL, Rohan LC. Effects of physiological fluids on physical-chemical characteristics and activity of topical vaginal microbicide products. Journal of Pharmaceutical Sciences. 97: 3123-39. PMID 17922539 DOI: 10.1002/Jps.21192 |
0.793 |
|
| 2007 |
Rohan LC, Hillier SL, Dezzutti CS. Preventing the sexual transmission of HIV-1 with topical microbicides: another piece of the equation. The Journal of Infectious Diseases. 196: 1285-7. PMID 17922391 DOI: 10.1086/522610 |
0.423 |
|
| 2007 |
Patton DL, Cosgrove Sweeney YT, Balkus JE, Rohan LC, Moncla BJ, Parniak MA, Hillier SL. Preclinical safety assessments of UC781 anti-human immunodeficiency virus topical microbicide formulations Antimicrobial Agents and Chemotherapy. 51: 1608-1615. PMID 17353240 DOI: 10.1128/Aac.00984-06 |
0.451 |
|
| 2006 |
Gupta P, Ratner D, Patterson BK, Kulka K, Rohan LC, Parniak MA, Isaacs CE, Hillier S. Use of frozen-thawed cervical tissues in the organ culture system to measure anti-HIV activities of candidate microbicides. Aids Research and Human Retroviruses. 22: 419-24. PMID 16706618 DOI: 10.1089/Aid.2006.22.419 |
0.434 |
|
| 2004 |
Sassi AB, McCullough KD, Cost MR, Hillier SL, Rohan LC. Permeability of tritiated water through human cervical and vaginal tissue. Journal of Pharmaceutical Sciences. 93: 2009-16. PMID 15236450 DOI: 10.1002/Jps.20107 |
0.747 |
|
| 2004 |
Rohan LC, Ratner D, McCullough K, Hiller SL, Gupta P. Measurement of anti-HIV activity of marketed vaginal products and excipients using a PBMC-based in vitro assay. Sexually Transmitted Diseases. 31: 143-8. PMID 15076925 DOI: 10.1097/01.Olq.0000114655.79109.Ed |
0.452 |
|
| 2003 |
Olmsted SS, Meyn LA, Rohan LC, Hillier SL. Glycosidase and proteinase activity of anaerobic gram-negative bacteria isolated from women with bacterial vaginosis. Sexually Transmitted Diseases. 30: 257-61. PMID 12616147 DOI: 10.1097/00007435-200303000-00016 |
0.336 |
|
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