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Jeffrey D. Winkler - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
New Synthetic Pathways
Website:
http://webdev.chem.upenn.edu/chem/research/faculty.php?id=39

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Jeon H, Winkler JD. Synthesis of Cyclohexane-Angularly-Fused Triquinanes. Synthesis. 53: 475-488. PMID 34334830 DOI: 10.1055/s-0040-1705953  0.308
2021 Doytchinova K, Winkler JD. Synthesis of the Core Ring System of the Antiosteoporotic Citrofulvicin. Organic Letters. PMID 34085522 DOI: 10.1021/acs.orglett.1c01216  0.33
2020 Higgins T, Winkler JD. Synthesis and Applications of the C2-Symmetrical Diamine, 2,7-diazabicyclo[4.4.1]undecane. The Journal of Organic Chemistry. PMID 32353240 DOI: 10.1021/Acs.Joc.0C00829  0.426
2020 Crocker KE, Pei Y, Robertson ES, Winkler JD. Synthesis of a novel bruceantin analog via intramolecular etherification Canadian Journal of Chemistry. 98: 270-272. DOI: 10.1139/Cjc-2019-0437  0.517
2019 Yan Q, Carroll PJ, Gau MR, Winkler JD, Joullié MM. A Transannular Rearrangement Reaction of a Pyrroloindoline Diketopiperazine. Organic Letters. PMID 31414824 DOI: 10.1021/Acs.Orglett.9B02084  0.722
2019 Wangtrakuldee P, Adeniji AO, Zang T, Duan L, Khatri B, Twenter BM, Estrada MA, Higgins TF, Winkler JD, Penning TM. A 3-(4-Nitronaphthen-1-yl) amino-benzoate analog as a Bifunctional AKR1C3 Inhibitor with AR Antagonist Activity: Head to Head Comparison with Other Advanced AKR1C3 Targeted Therapeutics. The Journal of Steroid Biochemistry and Molecular Biology. PMID 30641225 DOI: 10.1016/J.Jsbmb.2019.01.001  0.306
2018 Goldstein SR, Liu C, Safo MK, Nakagawa A, Zapol WM, Winkler JD. Design, Synthesis, and Biological Evaluation of Allosteric Effectors That Enhance CO Release from Carboxyhemoglobin. Acs Medicinal Chemistry Letters. 9: 714-718. PMID 30034606 DOI: 10.1021/Acsmedchemlett.8B00166  0.58
2018 Estrada MA, Zhao X, Lorent K, Kriegermeier A, Nagao SA, Berritt S, Wells RG, Pack M, Winkler JD. Synthesis and Structure-Activity Relationship Study of Biliatresone, a Plant Isoflavonoid That Causes Biliary Atresia. Acs Medicinal Chemistry Letters. 9: 61-64. PMID 29348813 DOI: 10.1021/Acsmedchemlett.7B00479  0.376
2017 Nakamura E, Winkler JD, Aggarwal VK. Gilbert Stork (1921-2017). Angewandte Chemie (International Ed. in English). PMID 29193592 DOI: 10.1002/Anie.201711474  0.648
2017 Rebecca VW, Nicastri MC, McLaughlin N, Fennelly C, McAfee Q, Ronghe A, Nofal M, Lim CY, Witze E, Chude CI, Zhang G, Alicea GM, Piao S, Murugan S, Ojha R, ... ... Winkler JD, et al. A unified approach to targeting the lysosome's degradative and growth signaling roles. Cancer Discovery. PMID 28899863 DOI: 10.1158/2159-8290.Cd-17-0741  0.302
2015 Nishimura Y, McLaughlin NP, Pan J, Goldstein S, Hafenstein S, Shimizu H, Winkler JD, Bergelson JM. The Suramin Derivative NF449 Interacts with the 5-fold Vertex of the Enterovirus A71 Capsid to Prevent Virus Attachment to PSGL-1 and Heparan Sulfate. Plos Pathogens. 11: e1005184. PMID 26430888 DOI: 10.1371/Journal.Ppat.1005184  0.522
2015 Chatwichien J, Basu S, Murphy ME, Hamann MT, Winkler JD. Design, Synthesis and Biological Evaluation of β-Carboline Dimers Based on the Structure of Neokauluamine. Tetrahedron Letters. 56: 3515-3517. PMID 26257442 DOI: 10.1016/J.Tetlet.2015.01.142  0.348
2015 Vasilevskaya IA, Selvakumaran M, Hierro LC, Goldstein SR, Winkler JD, O'Dwyer PJ. Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNA-Damaging Agents. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26023085 DOI: 10.1158/1078-0432.Ccr-15-0352  0.523
2012 Winkler JD, Twenter BM, Gendrineau T. A NEW APPROACH TO THE SYNTHESIS OF SUBSTITUTED PHENAZINES VIA PALLADIUM-CATALYZED ARYL LIGATION(i.) Heterocycles. 84. PMID 24403722 DOI: 10.3987/Com-11-S(P)76  0.474
2012 Chen M, Adeniji AO, Twenter BM, Winkler JD, Christianson DW, Penning TM. Crystal structures of AKR1C3 containing an N-(aryl)amino-benzoate inhibitor and a bifunctional AKR1C3 inhibitor and androgen receptor antagonist. Therapeutic leads for castrate resistant prostate cancer. Bioorganic & Medicinal Chemistry Letters. 22: 3492-7. PMID 22507964 DOI: 10.1016/J.Bmcl.2012.03.085  0.303
2012 Adeniji AO, Twenter BM, Byrns MC, Jin Y, Chen M, Winkler JD, Penning TM. Development of potent and selective inhibitors of aldo-keto reductase 1C3 (type 5 17β-hydroxysteroid dehydrogenase) based on N-phenyl-aminobenzoates and their structure-activity relationships. Journal of Medicinal Chemistry. 55: 2311-23. PMID 22263837 DOI: 10.1021/Jm201547V  0.365
2011 Winkler JD, Isaacs AK, Xiang C, Baubet V, Dahmane N. Design, synthesis, and biological evaluation of estrone-derived hedgehog signaling inhibitors. Tetrahedron. 67: 10261-10266. PMID 22199406 DOI: 10.1016/J.Tet.2011.10.028  0.787
2011 Haimowitz T, Fitzgerald ME, Winkler JD. STUDIES DIRECTED TOWARD THE SYNTHESIS OF NAKADOMARIN A. Tetrahedron Letters. 52: 2162-2164. PMID 22013283 DOI: 10.1016/J.Tetlet.2010.11.134  0.815
2011 Isaacs AK, Xiang C, Baubet V, Dahmane N, Winkler JD. Studies directed toward the elucidation of the pharmacophore of steroid-based Sonic Hedgehog signaling inhibitors. Organic Letters. 13: 5140-3. PMID 21905689 DOI: 10.1021/Ol202020C  0.784
2011 Zhang Z, Baubet V, Ventocilla C, Xiang C, Dahmane N, Winkler JD. Stereoselective synthesis of F-ring saturated estrone-derived inhibitors of Hedgehog signaling based on cyclopamine. Organic Letters. 13: 4786-9. PMID 21842835 DOI: 10.1021/Ol2017966  0.354
2011 Adeniji AO, Twenter BM, Byrns MC, Jin Y, Winkler JD, Penning TM. Discovery of substituted 3-(phenylamino)benzoic acids as potent and selective inhibitors of type 5 17β-hydroxysteroid dehydrogenase (AKR1C3). Bioorganic & Medicinal Chemistry Letters. 21: 1464-8. PMID 21277203 DOI: 10.1016/J.Bmcl.2011.01.010  0.31
2011 Yano T, Kassovska-Bratinova S, Teh JS, Winkler J, Sullivan K, Isaacs A, Schechter NM, Rubin H. Reduction of clofazimine by mycobacterial type 2 NADH:quinone oxidoreductase: a pathway for the generation of bactericidal levels of reactive oxygen species. The Journal of Biological Chemistry. 286: 10276-87. PMID 21193400 DOI: 10.1074/Jbc.M110.200501  0.759
2009 Winkler JD, Isaacs A, Holderbaum L, Tatard V, Dahmane N. Design and synthesis of inhibitors of Hedgehog signaling based on the alkaloid cyclopamine. Organic Letters. 11: 2824-7. PMID 19552464 DOI: 10.1021/Ol900974U  0.787
2009 Choi S, Isaacs A, Clements D, Liu D, Kim H, Scott RW, Winkler JD, DeGrado WF. De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers. Proceedings of the National Academy of Sciences of the United States of America. 106: 6968-73. PMID 19359494 DOI: 10.1073/Pnas.0811818106  0.749
2009 Jo H, Fitzgerald ME, Winkler JD. An unusual pathway to cyclobutane formation via desulfurative intramolecular photocycloaddition of an enone benzothiazoline pair. Organic Letters. 11: 1685-7. PMID 19301922 DOI: 10.1021/Ol900186Y  0.378
2009 Winkler JD, Fitzgerald ME. Stereoselective synthesis of 8-substituted 6-azabicyclo[3.2.1]octan-3-ones Synlett. 562-564. DOI: 10.1055/S-0028-1087561  0.503
2007 Winkler JD, Londregan AT, Hamann MT. Synthetic modification of manzamine A via Grubbs metathesis. Novel structures with enhanced antibacterial and antiprotozoal properties. Organic Letters. 9: 4467-9. PMID 17918854 DOI: 10.1021/Ol701799C  0.702
2007 Jiang W, Mikochik PJ, Ra JH, Lei H, Flaherty KT, Winkler JD, Spitz FR. HIV protease inhibitor nelfinavir inhibits growth of human melanoma cells by induction of cell cycle arrest. Cancer Research. 67: 1221-7. PMID 17283158 DOI: 10.1158/0008-5472.Can-06-3377  0.747
2006 Ragains JR, Winkler JD. Pseudosymmetry in azabicyclo[2.1.1]hexanes. A stereoselective construction of the bicyclic core of peduncularine. Organic Letters. 8: 4437-40. PMID 16986919 DOI: 10.1021/Ol061577+  0.758
2006 Winkler JD, Ragains JR. Intramolecular photoaddition of vinylogous amides with allenes: a novel approach to the synthesis of pyrroles. Organic Letters. 8: 4031-3. PMID 16928066 DOI: 10.1021/Ol061453X  0.725
2006 Winkler JD, Asselin SM. Synthesis of novel heterocyclic structures via reaction of isocyanides with S-trans-enones. Organic Letters. 8: 3975-7. PMID 16928052 DOI: 10.1021/Ol061451C  0.805
2006 Winkler JD, Londregan AT, Ragains JR, Hamann MT. Synthesis and biological evaluation of manzamine analogues. Organic Letters. 8: 3407-9. PMID 16836417 DOI: 10.1021/Ol061320B  0.8
2006 Winkler JD, Lee EC. Photochemical route to the synthesis of thiolane 1-oxides. Journal of the American Chemical Society. 128: 9040-1. PMID 16834370 DOI: 10.1021/Ja060962R  0.61
2006 Winkler JD, Londregan AT, Hamann MT. Antimalarial activity of a new family of analogues of manzamine A. Organic Letters. 8: 2591-4. PMID 16737321 DOI: 10.1021/Ol060848D  0.724
2005 Winkler JD, Oh K. A one-step synthesis of 2,3-dihydro-4H-pyran-4-ones from 3-ethoxy alpha,beta-unsaturated lactones. Organic Letters. 7: 2421-3. PMID 15932213 DOI: 10.1021/Ol050702Z  0.43
2005 Winkler JD, Lee EC, Nevels LI. A Pauson-Khand approach to the synthesis of ingenol. Organic Letters. 7: 1489-91. PMID 15816734 DOI: 10.1021/Ol050103S  0.759
2005 Winkler JD, Oh K, Asselin SM. Synthesis of highly functionalized furanones via aldol reaction of 3-silyloxyfurans. Organic Letters. 7: 387-9. PMID 15673246 DOI: 10.1021/Ol047810Q  0.807
2005 Winkler JD, McLaughlin EC. Intramolecular photocycloaddition of dioxenones with alkynes: formation of secondary photoproducts from cyclobutene photoadducts. Organic Letters. 7: 227-9. PMID 15646964 DOI: 10.1021/Ol047795P  0.755
2004 Winkler JD, Asselin SM, Shepard S, Yuan J. Metathesis approach to the synthesis of polyheterocyclic structures from oxanorbornenes. Organic Letters. 6: 3821-4. PMID 15469358 DOI: 10.1021/Ol0484106  0.812
2004 Winkler JD, Mikochik PJ. Synthesis of cyclic hemiketals and spiroketals from dioxanorbornanes. Organic Letters. 6: 3735-7. PMID 15469336 DOI: 10.1021/Ol048578R  0.824
2003 Winkler JD, Quinn KJ, MacKinnon CH, Hiscock SD, McLaughlin EC. Tandem Diels-Alder/fragmentation approach to the synthesis of eleutherobin. Organic Letters. 5: 1805-8. PMID 12735782 DOI: 10.1021/Ol0345226  0.776
2002 Winkler JD, Rouse MB, Greaney MF, Harrison SJ, Jeon YT. The first total synthesis of (+/-)-ingenol. Journal of the American Chemical Society. 124: 9726-8. PMID 12175229 DOI: 10.1021/Ja026600A  0.805
2002 Winkler JD, Harrison SJ, Greaney MF, Rouse MB. Mechanistic observations on the unusual reactivity of dioxenone photosubstrates in the synthesis of ingenol Synthesis. 2150-2154. DOI: 10.1055/S-2002-34370  0.779
2002 Weiner W, Winkler J, Zimmerman SC, Czarnik AW, Breslow R. Mimics of tryptophan synthetase and of biochemical dehydroalanine formation Cheminform. 16. DOI: 10.1002/Chin.198543345  0.726
2001 Kwak YS, Winkler JD. Synthesis of 6-aza-bicyclo[3,2,1]octan-3-ones via vinylogous imide photochemistry: an approach to the synthesis of the hetisine alkaloids. Journal of the American Chemical Society. 123: 7429-30. PMID 11472177 DOI: 10.1021/Ja010542W  0.667
2001 Ichinose F, Erana-Garcia J, Hromi J, Raveh Y, Jones R, Krim L, Clark MW, Winkler JD, Bloch KD, Zapol WM. Nebulized sildenafil is a selective pulmonary vasodilator in lambs with acute pulmonary hypertension. Critical Care Medicine. 29: 1000-5. PMID 11378612 DOI: 10.1097/00003246-200105000-00024  0.61
1999 Winkler JD, Doherty EM. The first total synthesis of (±)-Saudin [11] Journal of the American Chemical Society. 121: 7425-7426. DOI: 10.1021/Ja9916198  0.506
1999 Axten JM, Ivy R, Krim L, Winkler JD. Enantioselective synthesis of D-threo-methylphenidate [8] Journal of the American Chemical Society. 121: 6511-6512. DOI: 10.1021/Ja991466O  0.679
1999 Winkler JD, Kim S, Harrison S, Lewin NE, Blumberg PM. Synthesis and biological evaluation of highly functionalized analogues of ingenol Journal of the American Chemical Society. 121: 296-300. DOI: 10.1021/Ja9741842  0.639
1999 Winkler JD, Holland JM, Kasparec J, Axelsen PH. Design and synthesis of constrained epothilone analogs: The efficient synthesis of eleven-membered rings by olefin metathesis Tetrahedron. 55: 8199-8214. DOI: 10.1016/S0040-4020(99)00301-4  0.456
1998 Winkler JD, Axten JM. The First Total Syntheses of Ircinol A, Ircinal A, and Manzamines A and D. Journal of the American Chemical Society. 120: 6425-6426. PMID 25170173 DOI: 10.1021/Ja981303K  0.429
1998 Axten JM, Krim L, Kung HF, Winkler JD. A stereoselective synthesis of dl-threo-methylphenidate: Preparation and biological evaluation of novel analogues Journal of Organic Chemistry. 63: 9628-9629. DOI: 10.1021/Jo982214T  0.725
1998 Winkler JD, Kwak YS. An approach to controlled oligomerization via iterative Diels-Alder cycloadditions on solid supports Journal of Organic Chemistry. 63: 8634-8635. DOI: 10.1021/Jo9816358  0.554
1998 Winkler JD, McCoull W. Diels-alder reaction on solid supports using polymer-bound oxazolidinones Tetrahedron Letters. 39: 4935-4936. DOI: 10.1016/S0040-4039(98)00960-5  0.347
1998 Winkler JD, Doherty EM. Control of relative stereochemistry of quaternary carbon centers via the intramolecular dioxenone photocycloaddition: An approach to the synthesis of saudin Tetrahedron Letters. 39: 2253-2256. DOI: 10.1016/S0040-4039(98)00285-8  0.388
1998 Winkler JD, Axten J, Hammach AH, Kwak YS, Lengweiler U, Lucero MJ, Houk KN. Stereoselective synthesis of the tetracyclic core of manzamine via the vinylogous amide photocycloaddition cascade Tetrahedron. 54: 7045-7056. DOI: 10.1016/S0040-4020(98)00346-9  0.672
1997 Winkler JD, Kim HS, Kim S, Ando K, Houk KN. Stereoselective Synthesis of the Taxane Ring System via the Tandem Diels-Alder Cycloaddition. The Journal of Organic Chemistry. 62: 2957-2962. PMID 11671659 DOI: 10.1021/Jo961620E  0.486
1997 Kim S, Winkler JD. Approaches to the synthesis of ingenol Chemical Society Reviews. 26: 387-399. DOI: 10.1039/Cs9972600387  0.437
1997 Winkler JD, Stelmach JE, Siegel MG, Haddad N, Axten J, Dailey WP. An approach to the synthesis of the manzamine alkaloids via the vinylogous amide pHotocycloAddition/retro-mannich fragmentation/Mannich closure cascade (pharM) Israel Journal of Chemistry. 37: 47-67. DOI: 10.1002/Ijch.199700008  0.473
1996 Winkler JD. Tandem Dielsminus signAlder Cycloadditions in Organic Synthesis. Chemical Reviews. 96: 167-176. PMID 11848748 DOI: 10.1021/Cr950029Z  0.359
1996 Winkler JD, Holland JM, Peters DA. Synthesis of cyclopropyl taxane analogs via sequential Diels-Alder reactions Journal of Organic Chemistry. 61: 9074-9075. DOI: 10.1021/Jo961617V  0.475
1996 Winkler JD, Bhattacharya SK, Batey RA. Synthesis of a taxinine analog via the intramolecular Diels-Alder cycloaddition Tetrahedron Letters. 37: 8069-8072. DOI: 10.1016/0040-4039(96)01841-2  0.809
1996 Winkler JD, Stelmach JE, Axten J. Two highly efficient syntheses of scalemic azocines Tetrahedron Letters. 37: 4317-4318. DOI: 10.1016/0040-4039(96)00834-9  0.47
1995 Winkler JD, Hong B, Kim S, Lewin NE, Blumberg PM. On the Protein Kinase C Pharmacophore: Synthesis and Biological Activity of 4-Hydroxylated Analogs of Ingenol Synlett. 1995: 533-535. DOI: 10.1055/S-1995-5288  0.635
1995 Winkler JD, Hong B, Bahador A, Kazanietz MG, Blumberg PM. Inside-outside stereoisomerism. VII. Methodology for the Synthesis of 3-Oxygenated Ingenanes. The First Ingenol Analogs with High Affinity for Protein Kinase C The Journal of Organic Chemistry. 60: 1381-1390. DOI: 10.1021/Jo00110A048  0.619
1995 Winkler JD, Bowen CM, Liotta F. [2 + 2] Photocycloaddition/fragmentation strategies for the synthesis of natural and unnatural products Chemical Reviews. 95: 2003-2020. DOI: 10.1021/Cr00038A010  0.388
1995 Winkler JD, Bhattacharya SK, Liotta F, Batey RA, Heffernan GD, Cladingboel DE, Kelly RC. Stereoselective synthesis of a synthon for the A-ring of taxol from R-(+)-verbenone Tetrahedron Letters. 36: 2211-2214. DOI: 10.1016/0040-4039(95)00257-D  0.789
1995 Winkler JD, Kim HS, Kim S. A highly efficient synthesis of taxanes via the tandem Diels-Alder reaction Tetrahedron Letters. 36: 687-690. DOI: 10.1016/0040-4039(94)02353-D  0.485
1995 Winkler JD, Hong BC. Transannular radical reactions in bicycloalkanes with 'inside-outside' stereochemistry. An unusual bridgehead hydroxylation Tetrahedron Letters. 36: 683-686. DOI: 10.1016/0040-4039(94)02352-C  0.641
1994 Winkler JD, Kim S, Condroski KR, Asensio A, Houk KN. Stereoselective Synthesis of Polycyclic Ring Systems via the Tandem Diels-Alder Reaction Journal of Organic Chemistry. 59: 6879-6881. DOI: 10.1021/Jo00102A002  0.46
1994 Winkler JD, Henegar KE, Hong BC, Williard PG. Inside-outside stereoisomerism. 6. + synthesis of trans-bicyclo[4.4.1]undecan-11-one and the first stereoselective construction of the tricyclic nucleus of the ring system of the ingenane diterpenes Journal of the American Chemical Society. 116: 4183-4188. DOI: 10.1021/Ja00089A006  0.741
1994 Winkler JD, Kim S, Condroski KR, Asensio A, Houk KN. Stereoselective synthesis of polycyclic ring systems via the tandem Diels-Alder reaction Journal of Organic Chemistry. 59: 6879-6881.  0.353
1993 Winkler JD, Gretler EA, Williard PG. Studies directed toward the synthesis of the ingenane diterpenes. An unexpected synthesis of trans-bicyclo[5.3.0]decanes Journal of Organic Chemistry. 58: 1973-1975. DOI: 10.1021/Jo00059A067  0.657
1993 Winkler JD, Hong BC, Bahador A, Kazanietz MG, Blumberg PM. Synthesis of ingenol analogs wth affinity for protein kinase C Bioorganic and Medicinal Chemistry Letters. 3: 577-580. DOI: 10.1016/S0960-894X(01)81232-4  0.642
1993 Winkler JD, Shao B. On the stereoselectivity of the intramolecular dioxenone photocycloaddition Tetrahedron Letters. 34: 3355-3358. DOI: 10.1016/S0040-4039(00)79154-4  0.343
1993 Winkler JD, Siegel MG. A novel photochemical synthesis of pyrroles from β-ketovinylogous amides Tetrahedron Letters. 34: 7697-7700. DOI: 10.1016/S0040-4039(00)61542-3  0.348
1993 Winkler JD, Siegel MG, Stelmach JE. A highly stereoselective approach to the synthesis of the manzamine alkaloids via the intramolecular vinylogous amide photocycloaddition Tetrahedron Letters. 34: 6509-6512. DOI: 10.1016/0040-4039(93)88091-V  0.458
1992 Winkler JD, Subrahmanyam D. Studies directed towards the synthesis of taxol: Preparation of C-13 oxygenated taxane congeners Tetrahedron. 48: 7049-7056. DOI: 10.1016/S0040-4020(01)91213-X  0.393
1991 Winkler JD, Hong BC, Hey JP, Williard PG. Inside-Outside Stereoisomerism. 5. Synthesis and Reactivity of trans-Bicycle( n.3.1 Ialkanones Prepared via the Intramolecular Photocycloaddition of Dioxenonest9S Journal of the American Chemical Society. 113: 8839-8846. DOI: 10.1021/Ja00023A037  0.668
1991 Winkler JD, Gretler EA. Stereoselective cyclopropanation of homoallylic alcohols. Formal attachment of a cyclopropane to a preexisting ring Tetrahedron Letters. 32: 5733-5736. DOI: 10.1016/S0040-4039(00)93542-1  0.366
1991 Winkler JD, Hong BC, Hey JP, Williard PG. Inside-outside stereoisomerism. 5. Synthesis and reactivity of trans-bicyclo[n.3.1]alkanones prepared via the intramolecular photocycloaddition of dioxenones Journal of the American Chemical Society. 113: 8839-8846.  0.566
1990 Winkler JD, Scott RD, Williard PG. Asymmetric induction in the vinylogous amide photocycloaddition reaction. A formal synthesis of vindorosine Journal of the American Chemical Society. 112: 8971-8975. DOI: 10.1021/Ja00180A049  0.666
1989 Winkler JD, Lee CS, Rubo L, Muller CL, Squattrito PJ. Stereoselective synthesis of the tricyclic skeleton of the taxane diterpenes. The first C-silylation of a ketone enolate Journal of Organic Chemistry. 54: 4491-4493. DOI: 10.1021/Jo00280A007  0.355
1989 Winkler JD, Muller CL, Hey JP, Ogilvie RJ, Haddad N, Squattrito PJ, Williard PG. The effect of chromophore transposition on the stereochemical outcome of the intramolecular dioxenone photocycloaddition reaction Tetrahedron Letters. 30: 5211-5214. DOI: 10.1016/S0040-4039(01)93744-X  0.636
1989 Winkler JD, Sridar V, Siegel MG. Ten-membered ring templates for stereoselective radical cyclizations Tetrahedron Letters. 30: 4943-4946. DOI: 10.1016/S0040-4039(01)80549-9  0.376
1989 Winkler JD, Haddad N, Ogilvie RJ. Intramolecular photocycloaddition and retro-mannich fragmentation of acyclic tertiary vinylogous amides Tetrahedron Letters. 30: 5703-5704. DOI: 10.1016/S0040-4039(00)76175-2  0.369
1988 Winkler JD, Muller CL, Scott RD. A new method for the formation of nitrogen-containing ring systems via the intramolecular photocycloaddition of vinylogous amides. A synthesis of mesembrine Journal of the American Chemical Society. 110: 4831-4832. DOI: 10.1021/Ja00222A053  0.421
1988 Winkler JD, Hey JP, Williard PG. Inside-outside stereoisomerism III: The synthesis of trans-bicyclo[4.3.1]decan-10-one+ Tetrahedron Letters. 29: 4691-4694. DOI: 10.1016/S0040-4039(00)80582-1  0.654
1987 Winkler JD, Hey JP, Hannon FJ, Williard PG. Intramolecular photocycloadditions on dioxolenones: An efficient method for the synthesis of medium-sized rings Heterocycles. 25: 55-60. DOI: 10.3987/S-1987-01-0055  0.603
1987 Winkler JD, Henegar KE, Williard PG. Inside-outside stereoisomerism. 2. Synthesis of the carbocyclic ring system of the ingenane diterpenes via the intramolecular dioxolenone photocycloaddition Journal of the American Chemical Society. 109: 2850-2851. DOI: 10.1021/Ja00243A062  0.639
1987 Henegar KE, Winkler JD. A new method for the synthesis of dioxolenones via the carboxylation of ketone enolates with anisyl cyanoformate Tetrahedron Letters. 28: 1051-1054. DOI: 10.1016/S0040-4039(00)95908-2  0.439
1986 Winkler JD, Hey JP, Williard PG. Inside-outside stereoisomerism: The synthesis of trans-bicyclo[5.3.1]undecan-11-one Journal of the American Chemical Society. 108: 6425-6427. DOI: 10.1021/Ja00280A071  0.651
1986 Breslow R, Czarnik AW, Lauer M, Leppkes R, Winkler J, Zimmerman S. Mimics of transaminase enzymes Journal of the American Chemical Society. 108: 1969-1979. DOI: 10.1021/Ja00268A040  0.679
1986 Winkler JD, Sridar V. Stereochemical control of transannular radical cyclizations. A new approach to the synthesis of linearly fused cyclopentanoids Journal of the American Chemical Society. 108: 1708-1709. DOI: 10.1021/Ja00267A061  0.326
1986 Winkler JD, Hey JP, Darling SD. Studies directed towards the synthesis of taxane diterpenes: A remarkable rearrangement Tetrahedron Letters. 27: 5959-5962. DOI: 10.1016/S0040-4039(00)85372-1  0.41
1986 Winkler JD, Hershberger PM, Springer JP. A stereoselective synthesis of the azaspiboundecane ring system of (-)-histrionicotoxin from (+)-glutamic acid Tetrahedron Letters. 27: 5177-5180. DOI: 10.1016/S0040-4039(00)85162-X  0.37
1986 Breslow R, Czarnik AW, Lauer M, Leppkes R, Winkler J, Zimmerman S. Mimics of Transaminase Enzymes. Cheminform. 17. DOI: 10.1002/Chin.198632320  0.679
1985 Weiner W, Winkler J, Zimmerman SC, Czarnik AW, Breslow R. Mimics of Tryptophan Synthetase and of Biochemical Dehydroalanine Formation Journal of the American Chemical Society. 107: 4093-4094. DOI: 10.1021/Ja00299A064  0.726
1984 Winkler J, Coutouli-Argyropoulou E, Leppkes R, Breslow R. Artificial Transaminase Carrying A Synthetic Macrocyclic Binding Group Cheminform. 15. DOI: 10.1002/Chin.198409127  0.442
1983 Winkler J, Coutouli-Argyropoulou E, Leppkes R, Breslow R. Artificial transaminase carrying a synthetic macrocyclic binding group Journal of the American Chemical Society. 105: 7198-7199. DOI: 10.1021/Ja00362A045  0.442
1983 Stork G, Winkler JD, Saccomano NA. Stereochemical control in the construction of vicinally substituted cyclopentanes and cyclohexanes. Intramolecular conjugate addition of β-ketoester anions. Tetrahedron Letters. 24: 465-468. DOI: 10.1016/S0040-4039(00)81438-0  0.763
1982 Stork G, Winkler JD, Shiner CS. Stereochemical control of intramolecular conjugate addition. A short, highly stereoselective synthesis of adrenosterone Journal of the American Chemical Society. 104: 3767-3768. DOI: 10.1021/Ja00377A058  0.606
1982 Stork G, Shiner CS, Winkler JD. Stereochemical control of the internal Michael reaction. A new construction of trans-hydrindane systems Journal of the American Chemical Society. 104: 310-312. DOI: 10.1021/Ja00365A067  0.544
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